| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
We tried to generate iPS cells from our transgenic rat having drug-inducible reprogramming factors. However, there were some difficulties in mating. Then, as a first step to generate iPS cells and to analyze the reprogramming mechanisms, I focused on Oct4-binding sites in the nanog gene which is a marker gene of ES cells. I identified novel 9 novel Oct4-binding sequences in the rat nanog gene.
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