KAKEN — Research Projects | Researcher Number: 00220400

Search Results: 16 results / Researcher Number: 00220400

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1. Mechanical elucidation of the migration of endoscopy-guided biliary stents and proposal of measures to prevent migration

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Review Section	Basic Section 18010:Mechanics of materials and materials-related
Research Institution	Kyushu Institute of Technology
Principal Investigator	山田宏九州工業大学, 大学院生命体工学研究科, 教授
Project Period (FY)	2024-04-01 – 2027-03-31Granted
Keywords	ステント / 胆管胃吻合術 / 逸脱 / 材料力学試験 / 有限要素解析
Outline of Research at the Start	超音波内視鏡下の胆管胃吻合術における早期偶発症の一つであるステント逸脱の発生率低下のため，ステントの基本的力学特性や留置形態の知見に加えて，柔らかで動きやすい二つの臓器とそれを繋ぐステントの力学的相互作用の解明を行う．そのため，手術毎の画像解析，と畜解体後のブタ胃・肝臓を用いた材料力学試験，数値シミ ...

2. Investigation of the effect of subcutaneous microstructure and gel-like mat to prevent vascular closure against body surface pressure accompanied with shear

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Review Section	Basic Section 18010:Mechanics of materials and materials-related
Research Institution	Kyushu Institute of Technology
Principal Investigator	Yamada Hiroshi 九州工業大学, 大学院生命体工学研究科, 教授
Project Period (FY)	2020-04-01 – 2023-03-31Completed
Keywords	褥瘡 / 皮下組織 / ゲル / 圧力 / ずれ / マットレス / ゲル素材 / 血管 / 圧縮
Outline of Research at the Start	皮下組織は結合力が弱く，微細構造と力の伝達との関係の解明なしには，皮下組織・骨格筋内の血管閉塞のメカニズムを解明できない．また，ゲル層やウレタンフォーム層からなるマットに圧迫とずれが同時に加わる場合の褥瘡予防効果の評価が不足している．そこで本研究では，褥瘡の発症条件や予防効果を力学的観点から定量的に ...
Outline of Final Research Achievements	In the subcutaneous adipose tissue which contacts with the skeletal muscle of the porcine shoulder, the displacement occurred mainly in the superficia ...

Research Products of this project	Journal Article (2 results) Presentation (17 results, of which Int'l Joint Research: 2 results) Book (1 results)

3. Quantitative elucidation of mechanical factors that cause vascular occlusion in soft tissues and the effect of mattresses on pressure ulcer prevention

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Kyushu Institute of Technology
Principal Investigator	Yamada Hiroshi 九州工業大学, 大学院生命体工学研究科, 教授
Project Period (FY)	2017-04-01 – 2020-03-31Completed
Keywords	皮下組織 / 静脈 / 閉塞 / 有限要素解析 / マットレス / ゲル素材 / ずれ抵抗 / 超弾性 / 軟部組織 / せん断 / 粘弾性 / 横弾性係数 / 血管 / 体表面圧 / ずれ / 変形 / 材料力学 / 生体工学 / 看護学
Outline of Final Research Achievements	When pressure or shear displacement was applied to the skin surface of the forearm of men in their twenties, the vein in the subcutaneous tissue was e ...

Research Products of this project	Journal Article (1 results, of which Int'l Joint Research: 1 results, Peer Reviewed: 1 results) Presentation (16 results, of which Int'l Joint Research: 1 results)

4. Investigation of the effects of inhomogeneity of atheromatous plaques on damage and rupture of the artery with a use of human autopsy samples

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Kyushu Institute of Technology
Principal Investigator	Yamada Hiroshi 九州工業大学, 大学院生命体工学研究科, 教授
Project Period (FY)	2014-04-01 – 2017-03-31Completed
Keywords	粥状動脈硬化 / 線維性被膜 / 石灰化 / プラーク内出血 / バルーン / ひずみ / X線CT / 画像相関法 / 内膜剥離術 / 頸動脈 / 破断 / 単軸引張試験 / 有限要素解析 / バルーンカテーテル / プラーク破裂 / Ｘ線ＣＴ / 伸展
Outline of Final Research Achievements	By identifying the calcified regions by micro X-ray CT, observing cross sections of stained tissues with light microscopy, and performing a strain ana ...

Research Products of this project	Journal Article (1 results, of which Peer Reviewed: 1 results, Open Access: 1 results, Acknowledgement Compliant: 1 results) Presentation (12 results, of which Int'l Joint Research: 3 results)

5. Investigation of the correlation between mechanical information and pathological information on plaque rupture using human carotid arteries obtained at autopsy

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Kyushu Institute of Technology
Principal Investigator	YAMADA Hiroshi 九州工業大学, 生命体工学研究科(研究院), 教授
Project Period (FY)	2011 – 2013Completed
Keywords	粥状動脈硬化 / 応力－ひずみ関係 / 線維性被膜 / プラーク / コラーゲン / エラスチン / 繊維性被膜 / 動脈硬化 / 有限要素解析 / バイオメカニクス / 頸動脈 / 伸展試験
Research Abstract	We compared the fibrous caps, which develop with plaques, with normal regions for human carotid arteries and thoracic aortas obtained at autopsy. A si ...

Research Products of this project	Journal Article (2 results, of which Peer Reviewed: 2 results) Presentation (16 results)

6. Evaluation of time response of skin cells under artificial ischemia condition and a delay of pressure ulcer through an adjustment of physical environment

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Kyushu Institute of Technology
Principal Investigator	YAMADA Hiroshi Kyushu Institute of Technology
Project Period (FY)	2008 – 2010Completed
Keywords	生体力学 / 褥瘡 / 微小血管 / 有限要素解析 / 体積変化 / 粘弾性 / 空気圧 / 周期的負荷 / 線維芽細胞 / 低酸素 / 接着 / 温度 / 二価陽イオン / エネルギ代謝
Research Abstract	Single-layered rabbit fibroblast-like cells in culture are insensitive to a reduction of oxygen and sensitive to the temperature due to the fact that ...

Research Products of this project	Presentation (11 results)

7. Assessment of multiple effects of strain, temperature and oxygen concentration on dermal cells for a delay of occurrence of pressure ulcer

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Kyushu Institute of Technology
Principal Investigator	YAMADA Hiroshi Kyushu Institute of Technology, Graduate School of Life Science and Systems Engineering, Associate professor
Project Period (FY)	2006 – 2007Completed
Keywords	pressure ulcer / dermal fibroblast / temperature / nutrition / compression / oxygen concentration / finite element analysis
Research Abstract	Conditions of nutrition(a nutritious condition with a mixture of Dulbecco's modified eagle medium and Ham's F-12, and a nutrient-free condition with D ...

Research Products of this project	Journal Article (1 results) Presentation (4 results)

8. Effect of mechanical fields in a vascular endothelial cell on the dynamics of the formation of actin cytoskeleton

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Kyushu Institute of Technology
Principal Investigator	YAMADA Hiroshi Kyushu Institute of Technology, School of Life Science and Systems Engineering, Associate professor
Project Period (FY)	2003 – 2004Completed
Keywords	Vascular endothelial cell / Stress fiber / Cyclic deformation / Orientation / Strain / Actin filament / Polymerization / Crosslinking
Research Abstract	Three-dimensional orientation of stress fibers in vascular endothelial cells was observed by confocal scanning laser microscopy after staining actin f ...

Research Products of this project	Journal Article (4 results) Publications (1 results)

9. Analysis of damage phenomena in cells and informatics of vascular microstructure for medical applications

Research Project

Research Category	Grant-in-Aid for Scientific Research on Priority Areas
Review Section	Science and Engineering
Research Institution	Kyushu Institute of Technology
Principal Investigator	YAMADA Hiroshi Kyushu Institute of Technology, Graduate School of Life Science and Systems Engineering, Associate professor
Project Period (FY)	2003 – 2006Completed
Keywords	Vascular endothelial cell / Finite element analysis / Freezing and thawing / Stress strain relationship / Damage / Histological change / Shock wave
Research Abstract	To assist medical diagnosis and treatment of the cardiovascular system, numerical analyses can be used to predict phenomena which cannot be intuitivel ...

Research Products of this project	Journal Article (14 results, of which Peer Reviewed: 2 results) Presentation (16 results) Book (6 results)

10. Evaluation of person-handling techniques in care work

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	体育学
Research Institution	Nagoya University
Principal Investigator	HIRUTA Shuichi Nagoya University, Research Center of Health, Physical Fitness and Sports, Associate Prof.
Project Period (FY)	2001 – 2002Completed
Keywords	care / caregiver / client / bed / wheelchair / workload / security
Research Abstract	Two experimental studies were carried out to compare caregivers' workload and client's evaluation of security among different person-handling techniqu ...

Research Products of this project	Publications (2 results)

11. Formulation of hypotheses and numerical simulations for cytoskeletal remodeling in vascular endothelial cells under physiological conditions from the viewpoint of mechanics

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Kyushu Institute of Technology
Principal Investigator	YAMADA Hiroshi Kyushu Institute of Technology, Associate Professor
Project Period (FY)	2001 – 2002Completed
Keywords	Cell mechanics / Vascular endothelial cell / Stress fiber / Cyclic deformation / Orientation / Numerical simulation
Research Abstract	It is hypothesized that a stress fiber in an adherent vascular endothelial cell orients in the direction in which the strain in the stress fiber is sm ...

Research Products of this project	Publications (3 results)

12. Investigation of Mechanical Effect of the Heart Wall on the Coronary Circulation on the Basis of Motion Model with Various Diseases

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Materials/Mechanics of materials
Research Institution	Nagoya University
Principal Investigator	YAMADA Hiroshi Nagoya University, Graduate School of Engineering, Assistant Professor
Project Period (FY)	1999 – 2000Completed
Keywords	Heart / Blood Vessel / MRI / Constitutive Equation / Strain / Motion / Finite Element Analysis / Muscular Tissue
Research Abstract	A set of magnetic resonance (MR) images at a phase of the cardiac cycle were rendered and visualized as a three-dimensional (3-D) model with commercia ...

Research Products of this project	Publications (5 results)

13. 心筋繊維・血管間の力伝達機構の解明と心臓壁の微視的モデル化に関する研究

Research Project

Research Category	Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field	Materials/Mechanics of materials
Research Institution	Nagoya University
Principal Investigator	山田宏名古屋大学, 工学研究科, 講師
Project Period (FY)	1998Completed
Keywords	心筋 / 血管 / 平滑筋 / 脂肪層 / 有限要素解析 / 心臓壁 / 数学モデル / 応力解析
Research Abstract	本年度は生体軟組織を構成する能動的構成要素が心臓・血管系の生理的変形と力の伝達に及ぼす影響について理論的側面から解明した.血管の有限要素モデルは平滑筋組織に相当する能動的要素と弾性・膠原線維組織に相当する受動的要素が交互に層状に存在する円筒モデルとした.能動的要素は平滑筋の配向する血管の円周方向に収 ...

14. 筋線維とその周辺構成要素との相互作用に基づく筋組織の力学的挙動の記述に関する研究

Research Project

Research Category	Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field	Materials/Mechanics of materials
Research Institution	Nagoya University
Principal Investigator	山田宏名古屋大学, 工学部, 講師
Project Period (FY)	1996Completed
Keywords	筋線維 / 筋収縮 / 活性化 / 数学モデル / 力学的挙動
Research Abstract	本研究では平滑筋を豊富に含む筋型動脈等の筋組織を含む生態軟組織の力学的挙動について,筋線維と線維間に存在する結合組織が作る内部構造の力学的挙動への影響を検討した.

15. 毛細血管・筋線維の形成する微細組織が心臓壁の力学的挙動に果たす役割に関する研究

Research Project

Research Category	Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field	Materials/Mechanics of materials
Research Institution	Nagoya University
Principal Investigator	山田宏名古屋大学, 工学部, 講師
Project Period (FY)	1995Completed
Keywords	心臓 / 心筋 / 血管 / 力学的挙動 / 伸展性
Research Abstract	心臓壁を構成する多数の筋線維と毛細血管は微視的レベルで平行に並んだ構造を呈している。毛細血管から見れば、血管の周辺に筋線維が併走しているようにみえる。一方、巨視的なレベルにおいては、冠動脈の一部は局所的に平行な血管要素で、その周りに心筋組織が分布していると言える。本研究ではまず、微細組織の構造特性と ...

16. 心筋内圧の冠動脈圧に対する応答性に関する実験的研究

Research Project

Research Category	Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field	Materials/Mechanics of materials
Research Institution	Nagoya University
Principal Investigator	山田宏名古屋大学, 工学部, 講師
Project Period (FY)	1994Completed
Keywords	心筋内圧 / 二相体 / 圧力分布 / マイクロピペット / 浸透
Research Abstract	心臓壁は心筋線維とその間隙に存在する組織液,それに壁内に分布する血管とその中を流れる血液,結合組織等からなっている.これらの要素は固体要素と液体要素に分けることができる.心筋内圧は上述の心筋線維の間隙にある組織液の圧力と考えられる.本研究で購入した米国IPM社製サーボヌリング・プレッシャーシステムモ ...