KAKEN — Research Projects | Researcher Number: 60282620

Search Results: 14 results / Researcher Number: 60282620

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1. 電場電位の位相構築マップから読み解く霊長類大脳連合野の構造-機能連関

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Review Section	Medium-sized Section 51:Brain sciences and related fields
Research Institution	Niigata University
Principal Investigator	長谷川功新潟大学, 医歯学系, 教授
Project Period (FY)	2023-04-01 – 2027-03-31Granted
Keywords	マカクザル / 皮質脳波 / 前頭前野
Outline of Research at the Start	マカクザル、ヒト、マーモセットの前頭前野における電場電位の位相の機能構築と細胞構築との構造機能連関やfMRIの機能ネットワークとの関係、位相構築の種差や認知課題による変化を調べ、さらに位相が逆相な部位間の結合を化学遺伝学/組織学/生理学の手法により評価する。

2. 非侵襲的かつ脳深部へ適応可能な新規刺激法を用いたヒト記憶脳回路の解明

Research Project

Research Category	Grant-in-Aid for Challenging Research (Pioneering)
Review Section	Medium-sized Section 51:Brain sciences and related fields
Research Institution	Kochi University of Technology
Principal Investigator	竹田真己高知工科大学, 総合研究所, 特任教授
Project Period (FY)	2021-07-09 – 2025-03-31Granted
Keywords	記憶 / 脳波 / 超音波 / 電気生理 / fMRI
Outline of Research at the Start	経頭蓋集束超音波刺激を用いて、深部脳活動をコントロールした際の記憶パフォーマンスを検証することで、ヒトにおける記憶脳回路の因果的役割を解明する。（１）脳深部の内因性脳活動の位相にあわせた刺激が可能か、（２）刺激の効果範囲を十分に限定できるか、といった技術的課題をクリアするために、サルを対象に、経頭蓋 ...
Outline of Annual Research Achievements	経頭蓋集束超音波刺激を用いて、深部脳活動をコントロールした際の記憶パフォーマンスを検証することで、ヒトにおける記憶脳回路の因果的役割を解明する。（１）脳深部の内因性脳活動の位相にあわせた刺激が可能か、（２）刺激の効果範囲を十分に限定できるか、といった技術的課題をクリアするために、サルを対象に、経頭蓋 ...
Current Status of Research Progress	2: Research has progressed on the whole more than it was originally planned.

Research Products of this project	Journal Article (7 results, of which Peer Reviewed: 4 results, Open Access: 7 results) Presentation (7 results, of which Int'l Joint Research: 4 results)

3. 記憶形成を促進する睡眠中の脳回路メカニズムの因果的解明

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Review Section	Medium-sized Section 51:Brain sciences and related fields
Research Institution	Kochi University of Technology
Principal Investigator	竹田真己高知工科大学, 情報学群, 教授
Project Period (FY)	2020-04-01 – 2024-03-31Granted
Keywords	記憶 / 睡眠 / fMRI / EEG / tCS
Outline of Research at the Start	記憶想起中に出現する周波数依存的な協調的脳活動が睡眠中にもリプレイされることで記憶固定が促進されるか検証する。本検証を行うために、高い時空間スケールの脳活動計測と脳活動の位相に合わせたclosed-loop電流刺激法を組み合わせる。記憶想起に関連する脳活動パターンの特徴を深層学習デコーディングネット ...
Outline of Annual Research Achievements	睡眠中には、記憶の固定とよばれる起きている際に経験した事柄を長期記憶として貯蔵するための情報処理が行われていると考えられているが、いまだ全容解明されていない。我々は、記憶想起中に出現する周波数依存的な協調的脳活動が睡眠中にも再現（リプレイ）されることで記憶固定が促進されるとの仮説を立てた。本研究計画 ...
Current Status of Research Progress	2: Research has progressed on the whole more than it was originally planned.

Research Products of this project	Journal Article (10 results, of which Peer Reviewed: 7 results, Open Access: 7 results) Presentation (7 results, of which Int'l Joint Research: 4 results)

4. Brain organization for theory-of-mind and letter recognition-like behaviors in macaques—comparing homology with humans

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Review Section	Medium-sized Section 51:Brain sciences and related fields
Research Institution	Niigata University
Principal Investigator	長谷川功新潟大学, 医歯学系, 教授
Project Period (FY)	2019-04-01 – 2023-03-31Granted
Keywords	霊長類 / 心の理論 / 皮質脳波 / 言語 / 文字 / マカクザル / 誤信念
Outline of Research at the Start	我々は、脳科学のモデル動物としてヒトに最も近縁なマカクザルが、心の理論や言語等のヒトに固有と信じられてきた高次認知能力の下位機能に類似した行動を学習できることを示唆する手がかりを得た。しかし、これらの能力がヒトと相同の脳回路基盤を有するとは限らない。この問題を検証するため、マカクザルを対象として皮質 ...
Outline of Annual Research Achievements	目標(1)のDREADDsの分子イメージングでは、脳画像データの標準化とDREADDs発現部位の特定を進め、前頭前野と視床枕下部の結合が示唆された。しかしベクター注入前のデータの集団解析では、内在性信号強度の個体差が非常に大きいことが判明し、同一個体の導入前後での比較の必要性が示唆された。電気生理実 ...
Current Status of Research Progress	2: Research has progressed on the whole more than it was originally planned.

Research Products of this project	Journal Article (27 results, of which Peer Reviewed: 27 results, Open Access: 27 results) Presentation (20 results, of which Int'l Joint Research: 20 results, Invited: 2 results) Remarks (2 results)

5. Investigation of functional roles of ongoing brain activity in cognition and consciousness

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Basic / Social brain science
Research Institution	Kochi University of Technology
Principal Investigator	Nakahara Kiyoshi 高知工科大学, 情報学群, 教授
Project Period (FY)	2017-04-01 – 2021-03-31Completed
Keywords	エピソード記憶 / 記憶記銘 / 自発的脳活動 / 遠隔記憶 / システムレベルの固定化 / 前頭葉機能 / 機能的磁気共鳴画像法 / 皮質脳波法 / 前頭前野 / 脳広域ネットワーク / 記憶 / fMRI / ECoG / MVPA / 大規模脳ネットワーク / 長期記憶 / 近時記憶 / 記憶痕跡 / 陳述記憶 / 記憶の記銘 / 記憶の貯蔵 / 記憶の想起 / 神経科学 / MEG
Outline of Final Research Achievements	In the first half of this research project, we conducted an fMRI study to determine the relationship between encoding performance of episodic memory a ...

Research Products of this project	Journal Article (8 results, of which Peer Reviewed: 8 results, Open Access: 3 results) Presentation (3 results, of which Int'l Joint Research: 2 results, Invited: 1 results)

6. Animal model of cognitive impairments following gelastic seizures with the use of optogenetics

Research Project

Research Category	Grant-in-Aid for Challenging Exploratory Research
Research Field	Neurosurgery
Research Institution	Niigata University
Principal Investigator	Hasegawa Isao 新潟大学, 医歯学系, 教授
Project Period (FY)	2016-04-01 – 2018-03-31Completed
Keywords	笑い発作 / てんかん性脳症 / 視床下部 / 視床 / 光遺伝学 / チャネルロドプシン / 作業記憶 / 視床下部過誤腫 / 手綱核 / 視床背内側核 / ラット / 動物モデル / 前頭葉 / 脳神経外科学 / 脳・神経
Outline of Final Research Achievements	We introduced ChR2 into lateral hypothalamus using AAV9 viral vectors, and photostimulated ChR2-expressing axonal terminals in the dorsomedial and lat ...

Research Products of this project	Journal Article (2 results, of which Peer Reviewed: 2 results, Open Access: 1 results) Presentation (1 results)

7. Does high presence induced by high definition movies affect eye movements, the autonomic system, and sensation of depth?

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Biomedical engineering/Biomaterial science and engineering
Research Institution	Niigata University
Principal Investigator	IIJIMA Atsuhiko 新潟大学, 自然科学系, 教授
Project Period (FY)	2015-04-01 – 2019-03-31Completed
Keywords	輻輳眼球運動 / 映像酔い / 自律神経 / 生体影響 / 立体感 / 奥行き感覚 / 眼球運動 / 視覚情報処理 / 瞳孔 / 高精細映像 / 臨場感 / 立体視 / 資格情報処理 / 自律神経系
Outline of Final Research Achievements	Biological responses to high definition movies were investigated in focusing on vergence eye movements and the autonomic nervous system. The questions ...

Research Products of this project	Journal Article (1 results, of which Peer Reviewed: 1 results) Presentation (3 results)

8. Elucidating the autism pathogenesis through brain networks of "theory of mind" and modeling autism in non-human primates

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Psychiatric science
Research Institution	Niigata University
Principal Investigator	Someya Toshiyuki 新潟大学, 医歯学系, 教授
Project Period (FY)	2014-04-01 – 2019-03-31Completed
Keywords	心の理論 / 非言語的誤信念課題 / DREADD / マカクザル / 自閉スペクトラム症(ASD) / 霊長類動物モデル / 自閉スペクトラム症 / 自閉スぺlクトラム症 / 脳磁図 / 皮質脳波 / 拡散テンソル画像 / 自閉スぺクトラム症 / 皮質脳波（ECoG） / 脳磁図（MEG） / 自閉症スペクトラム障害 / 視線計測
Outline of Final Research Achievements	Human neuroimaging studies using various false-belief (FB) attribution tasks have revealed relationships between theory of mind (ToM) and brain networ ...

Research Products of this project	Journal Article (15 results, of which Peer Reviewed: 13 results, Open Access: 6 results) Presentation (20 results, of which Int'l Joint Research: 10 results, Invited: 1 results)

9. Neural mechanisms of visual communications revealed with electrocorticography.

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Brain biometrics
Research Institution	Niigata University
Principal Investigator	Hasegawa Isao 新潟大学, 医歯学系, 教授
Project Period (FY)	2014-04-01 – 2017-03-31Completed
Keywords	皮質脳波 / 視覚 / 前頭葉 / 信号伝搬 / マカクザル / 側頭葉 / 脳・神経
Outline of Final Research Achievements	We developed a method to quantify the information flow of the cerebral cortex as the local transfer entropy from the spatial pattern of the electrocor ...

Research Products of this project	Journal Article (42 results, of which Int'l Joint Research: 8 results, Peer Reviewed: 41 results, Acknowledgement Compliant: 4 results, Open Access: 16 results) Presentation (17 results, of which Int'l Joint Research: 16 results, Invited: 2 results)

10. How do autistic people recognize wholeness? From cognitive experiment to a nursing model.

Research Project

Research Category	Grant-in-Aid for Young Scientists (B)
Research Field	Kansei informatics
Research Institution	Osaka University (2014) Niigata University (2013)
Principal Investigator	NISHIYAMA Yuta 大阪大学, 学内共同利用施設等, 助教
Project Period (FY)	2013-04-01 – 2015-03-31Completed
Keywords	全体性認識 / 意味形成 / 認知発達 / 社会的認知発達
Outline of Final Research Achievements	Our research focused on a human ability to comprehend wholeness of some event. To examine how people develop a semantic formation and modulation, we c ...

Research Products of this project	Journal Article (1 results, of which Peer Reviewed: 1 results, Acknowledgement Compliant: 1 results) Presentation (8 results)

11. 敵か味方か？心の理論とシミュレーションの生物学的根拠を求めて

Publicly Offered Research

Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Review Section	Complex systems
Research Institution	Niigata University
Principal Investigator	長谷川功新潟大学, 医歯学系, 教授
Project Period (FY)	2012-04-01 – 2014-03-31Completed
Keywords	マカクザル / 社会認知 / 認知科学 / 動物 / 神経科学 / 心の理論
Research Abstract	意図を持って行動する者を助ける味方/邪魔する敵という社会関係の認知を『ミ』/『テ』の記号で報告させる行動実験パラダイムを開発し、ニホンザル2頭に学習させた。1頭で行動実験を進め、意図を持って行動する者とそれを協力/妨害する者の役割が入れ替わっても、場面が代わっても、また同じ場面で助け方や邪魔の仕方の ...
Project Area	Adolescent mind and self-regulation

Research Products of this project	Journal Article (7 results, of which Peer Reviewed: 7 results) Presentation (15 results, of which Invited: 5 results)

12. Neural mechanism of flexible cognition and use of symbols: a comparative macaque ECoG and human fMRI study

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Fusional brain recording science
Research Institution	Niigata University
Principal Investigator	HASEGAWA ISAO 新潟大学, 医歯学系, 教授
Project Period (FY)	2011-04-01 – 2014-03-31Completed
Keywords	マカクザル / 前頭葉 / 視覚 / 記号
Research Abstract	We developed a visual sign system where object categories were symbolically represented by distinct combinations of visual elements. Macaque monkeys ( ...

Research Products of this project	Journal Article (28 results, of which Peer Reviewed: 28 results) Presentation (57 results, of which Invited: 10 results) Patent(Industrial Property Rights) (6 results)

13. Neural activity related to construction of compound images in the macaque prefrontal cortex

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Neurophysiology and muscle physiology
Research Institution	Niigata University
Principal Investigator	HASEGAWA Isao Niigata University
Project Period (FY)	2008 – 2010Completed
Keywords	認知 / 記憶 / マカクザル / 前頭葉 / 電気生理 / 視覚 / 図形 / 大脳
Research Abstract	Japanese monkeys were trained in a symbolic construction matching-to-sample (SCMS) task in which 6 compound figures symbolically represent 6 objects. ...

Research Products of this project	Journal Article (13 results, of which Peer Reviewed: 10 results) Presentation (27 results) Book (2 results) Patent(Industrial Property Rights) (5 results)

14. Neural mechanisms of top-down control in primate prefrontal cortex : from single neuron to functional brain imaging

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	神経・脳内生理学
Research Institution	The University of Tokyo
Principal Investigator	HASEGAWA Isao The University of Tokyo, Graduate School of Medicine, Department of Physiology
Project Period (FY)	1999 – 2001Completed
Keywords	macaque / prefrontal cortex / single unit recording / functional MRI
Research Abstract	It is important to understand the brain mechanisms underlying memory and cognition from cellular events to individual behaviors. Toward this objective ...

Research Products of this project	Publications (38 results)