KAKEN — Research Projects | Researcher Number: 70135838

Search Results: 17 results / Researcher Number: 70135838

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1. ネオウイルス学：生命の源流から超個体、そしてエコ・スフィアーへ

Compiling the Research Achievements

Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Review Section	Biological Sciences
Research Institution	The University of Tokyo
Principal Investigator	河岡義裕東京大学, 医科学研究所, 特任教授
Project Period (FY)	2021-04-01 – 2022-03-31Completed
Keywords	ウイルス / 宿主との共生 / 多様性 / 生態系
Outline of Research at the Start	本研究提案では、ネオウイルス学で得られた研究成果を広く公開することによって、ネオウイルス学という学術分野が、今後の我が国の学術発展に貢献することを目的とする。具体的には、本研究における業績を取りまとめて、国内外の学術研究分野、および一般国民に向けて広く公開するために、(1) 「ネオウイルス学」業績集 ...
Outline of Annual Research Achievements	「ネオウイルス学」領域内の計画研究および公募研究で得られた各班それぞれの研究テーマについて研究成果を取りまとめ、さらに班間、あるいは、「共進化」、「共生」、「多様性」ユニット間の連携テーマの重要性・意義を考慮しつつ、領域全体の研究成果を取りまとめた。業績集を作成し、冊子体として印刷して領域内外で配布 ...
Project Area	Neo-virology: the raison d'etre of viruses

Research Products of this project	Remarks (1 results)

2. Surveillance of viruses causing zoonotic infections across three continents

Research Project

Research Category	Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
Review Section	Medium-sized Section 49:Pathology, infection/immunology, and related fields
Research Institution	The University of Tokyo
Principal Investigator	河岡義裕東京大学, 医科学研究所, 特任教授
Project Period (FY)	2018-10-09 – 2024-03-31Granted
Keywords	ウイルス / 人獣共通感染症 / 野生動物 / アフリカ / 南米 / アジア
Outline of Annual Research Achievements	地球レベルでの環境変化や野生動物との生活圏域の近接化により、新興感染症となりうる人獣共通感染症が、ヒト社会に侵入する可能性は増大している。最近の研究から、アフリカ、南米、アジア等の国々が、人獣共通感染症が発生しやすいホットスポットであると予測されているが、その実態は未だ不明である。そこで本研究では、 ...
Current Status of Research Progress	2: Research has progressed on the whole more than it was originally planned.

Research Products of this project	Int'l Joint Research (12 results) Journal Article (2 results, of which Int'l Joint Research: 1 results, Peer Reviewed: 2 results) Presentation (6 results, of which Int'l Joint Research: 3 results, Invited: 4 results) Remarks (2 results)

3. Neo-virology: the raison d'etre of viruses

Research Areas

Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Area Organizer	河岡義裕東京大学, 医科学研究所, 特任教授
Project Period (FY)	2016-06-30 – 2021-03-31
Ex-post Assessment Comments (Rating)	A: In light of the aim of introducing the research area into the research categories, expected outcomes of research have been produced.
Interim Assessment Comments (Rating)	A: In light of the aim of introducing the research area into the research categories, the expected progress has been made in research.

4. Neo-virology: the raison d'etre of viruses

International Activities Supporting Group

Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Review Section	Biological Sciences
Research Institution	The University of Tokyo
Principal Investigator	Kawaoka Yoshihiro 東京大学, 医科学研究所, 特任教授
Project Period (FY)	2016-06-30 – 2023-03-31Completed
Keywords	ウイルス / 国際共同研究 / ネットワーク構築 / 宿主との共生 / 生態
Outline of Final Research Achievements	We have developed and strengthened an international research network, supported and provided smooth overseas collection of research samples, promoted ...
Project Area	Neo-virology: the raison d'etre of viruses

Research Products of this project	Int'l Joint Research (24 results) Journal Article (447 results, of which Int'l Joint Research: 204 results, Peer Reviewed: 429 results, Open Access: 206 results) Book (3 results) Remarks (4 results) Patent(Industrial Property Rights) (4 results) Funded Workshop (14 results)

5. Symbiotic Relationship between Influenza Virus and Waterfowl in Nature

Planned Research

Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Review Section	Biological Sciences
Research Institution	Osaka University (2020, 2022) The University of Tokyo (2016-2019)
Principal Investigator	Watanabe Tokiko 大阪大学, 微生物病研究所, 教授
Project Period (FY)	2016-06-30 – 2021-03-31Completed
Keywords	インフルエンザウイルス / 共生 / バイローム解析 / ウイルスー宿主の共生関係 / ウイルス―宿主の共生関係
Outline of Final Research Achievements	We infected mallard ducks, the natural host of influenza viruses, with avian influenza viruses and found that they were asymptomatic, but innate immun ...
Project Area	Neo-virology: the raison d'etre of viruses

Research Products of this project	Int'l Joint Research (13 results) Journal Article (106 results, of which Int'l Joint Research: 50 results, Peer Reviewed: 84 results, Open Access: 9 results, Acknowledgement Compliant: 7 results) Presentation (99 results, of which Int'l Joint Research: 53 results, Invited: 55 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

6. Neo-virology: the raison d'etre of viruses

Administrative Group

Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Review Section	Biological Sciences
Research Institution	The University of Tokyo
Principal Investigator	Kawoaka Yoshihiro 東京大学, 医科学研究所, 特任教授
Project Period (FY)	2016-06-30 – 2021-03-31Completed
Keywords	ウイルス / 生態系 / 共進化 / 共生 / 多様性 / 宿主との共生 / 生態
Outline of Final Research Achievements	We have established a new academic field, designated as ‘Neo-virology’, in which we define a virus as a component of the global ecosystem and aim to e ...
Project Area	Neo-virology: the raison d'etre of viruses

Research Products of this project	Int'l Joint Research (28 results) Journal Article (503 results, of which Int'l Joint Research: 232 results, Peer Reviewed: 478 results, Open Access: 277 results, Acknowledgement Compliant: 22 results) Presentation (901 results, of which Int'l Joint Research: 268 results, Invited: 224 results) Book (11 results) Remarks (8 results) Patent(Industrial Property Rights) (5 results) Funded Workshop (2 results)

Research Products of this project

Int'l Joint Research (28 results) Journal Article (503 results, of which Int'l Joint Research: 232 results, Peer Reviewed: 478 results, Open Access: 277 results, Acknowledgement Compliant: 22 results) Presentation (901 results, of which Int'l Joint Research: 268 results, Invited: 224 results) Book (11 results) Remarks (8 results) Patent(Industrial Property Rights) (5 results) Funded Workshop (2 results)

7. インフルエンザウイルスのゲノムパッケージング機構の解明

Research Project

Research Category	Grant-in-Aid for JSPS Fellows
Research Field	Virology
Research Institution	The University of Tokyo
Principal Investigator	河岡義裕東京大学, 医科学研究所, 教授
Project Period (FY)	2016-11-07 – 2019-03-31Completed
Keywords	Influenza virus / Viral genome packaging / Virus budding / Virus-host interaction / Nanoscopy / Single-molecule FISH
Outline of Annual Research Achievements	In this project, we employed a nanoscopic approach that combines a cell unroofing method, freeze-etching electron microscopy and live atomic force mic ...

Research Products of this project	Journal Article (2 results, of which Int'l Joint Research: 2 results, Peer Reviewed: 2 results) Presentation (3 results)

8. 新型インフルエンザウイルスの出現機構とその制圧

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Virology
Research Institution	The University of Tokyo
Principal Investigator	河岡義裕東京大学, 医科学研究所, 教授
Project Period (FY)	2006 – 2007Completed
Keywords	インフルエンザ / パンデミック / 薬剤耐性ウイルス / パッケージング
Research Abstract	薬剤耐性H5N1ウイルスの病原性を調べるため、マウスおよびフェレットを用いた感染実験を進めていたが、同課題名で応募していた特別推進研究が採択されたため、そちらで引続き研究を進めていくこととなった。

9. Mechanism of emergence of new influenza viruses and their control

Research Project

Research Category	Grant-in-Aid for Specially Promoted Research
Review Section	Biological Sciences
Research Institution	The University of Tokyo
Principal Investigator	KAWAOKA Yoshihiro 東京大学, 医科学研究所, 教授
Project Period (FY)	2006 – 2010Completed
Keywords	インフルエンザ / 抗ウイルス薬 / 薬剤耐性ウイルス / レセプター / ウイルス粒子形成 / オセルタミビル / タミフル
Research Abstract	We studied the mechanisms by which H5N1 avian influenza viruses are transmitted to humans. We identified several amino acids that support efficient av ...

Research Products of this project	Journal Article (99 results, of which Peer Reviewed: 68 results) Presentation (36 results) Book (6 results) Remarks (39 results)

10. Ecology and pandemic planning of animal influenza virus

Research Project

Research Category	Grant-in-Aid for Scientific Research (S)
Research Field	Applied veterinary science
Research Institution	Hokkaido University
Principal Investigator	KIDA Hiroshi Hokkaido University, Graduate School of Veterinary Medicine, Professor
Project Period (FY)	2003 – 2006Completed
Keywords	influenza viruses / global surveillance / vaccine / antiviral / diagnosis
Research Abstract	H5N1 highly pathogenic avian influenza (HPAI) virus has spread in poultry from Southeast Asia to the north, Europe, and Africa. We have been conductin ...

Research Products of this project	Journal Article (27 results) Book (1 results) Patent(Industrial Property Rights) (1 results) Publications (6 results)

11. Influenza virus : the mechanism of genome packaging

Research Project

Research Category	Grant-in-Aid for Scientific Research on Priority Areas
Review Section	Biological Sciences
Research Institution	University of Tokyo
Principal Investigator	KAWAOKA Yoshihiro University of Tokyo, Institute of Medical Science, Professor
Project Period (FY)	2002 – 2005Completed
Keywords	virus / influenza virus / genome / packaging / reverse genetics
Research Abstract	The genome of influenza A viruses comprises eight negative-strand RNA segments. Although all eight segments must be present in cells for efficient vir ...

Research Products of this project	Journal Article (22 results) Book (1 results) Publications (3 results)

12. 半生インフルエンザウイルスベクターの開発

Research Project

Research Category	Grant-in-Aid for Exploratory Research
Research Field	Virology
Research Institution	The University of Tokyo
Principal Investigator	河岡義裕東京大学, 医科学研究所, 教授
Project Period (FY)	2001Completed
Keywords	インフルエンザウイルス / リバース・ジェネティクス / 変異ウイルス / ワクチン / NS2
Research Abstract	申請者らが開発したリバースジェネティクス法を用いて、安全性の高い不活化ワクチンと、侵入門戸の感染防御に有効な弱毒化生ワクチン双方の長所を兼ね備えたワクチン、すなわち細胞に一度だけ感染してウイルス蛋白質を発現し、粘膜免疫および細胞性免疫は誘導するが新たな感染性粒子は産生しない、"半生"ワクチンの開発を ...

Research Products of this project	Publications (1 results)

13. Development of influenza live vaccine by reverse genetics

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Virology
Research Institution	The University of Tokyo
Principal Investigator	KAWAOKA Yoshihiro University of Tokyo, IMS, Professor
Project Period (FY)	2001 – 2002Completed
Keywords	influenza virus / reverse genetics / live vaccine
Research Abstract	Influenza virus is a highly infectious respiratory pathogen of birds and mammals, including human. It often produces significant mobidity and mortalit ...

Research Products of this project	Journal Article (8 results) Publications (7 results)

14. Study on development of a live attenuated vaccine for equine influenza infection using reverse genetics

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Applied veterinary science
Research Institution	The University of Tokyo
Principal Investigator	GOTO Hideo The University of Tokyo, Institute of Medical Science, Research Associate
Project Period (FY)	2001 – 2003Completed
Keywords	equine influenza virus / live vaccine / reverse genetics / attenuation
Research Abstract	Equine influenza is an important contagious respiratory disease of horses. In the field of veterinary medicine, equine influenza is recognized as a se ...

Research Products of this project	Publications (33 results)

15. インフルエンザウイルス:ゲノム・パッケージングのメカニズム

Research Project

Research Category	Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section	Biological Sciences
Research Institution	The University of Tokyo
Principal Investigator	河岡義裕東京大学, 医科学研究所, 教授
Project Period (FY)	2001Completed
Keywords	インフルエンザウイルス / パッケージング・シグナル / リバース・ジェネティクス / NA蛋白質
Research Abstract	インフルエンザウイルスの粒子は、球形、ひも状、いびつなものなど様々な形をしており、その中には8本のRNA分節が存在している。これら8本のRNA分節がどのようにしてウイルス粒子中へ取り込まれるかについてはほとんど分かっていない。そこで本研究は、リバース・ジェネティクスを駆使してこの古典的命題を解明する ...

16. Ecological study of animal influenza viruses : To prepare for the emergence of pandemic influenza

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Applied veterinary science
Research Institution	Hokkaido University
Principal Investigator	KIDA Hiroshi Hokkaido University, Hokkaido University, Graduate School of Veterinary Medicine, Professor
Project Period (FY)	2000 – 2002Completed
Keywords	Influenza / migratory waterfowls / Pigs / Chickens / Epidemiological surveillance / Receptor specificity / Interspecies transmission
Research Abstract	To provide information on the precursor genes of the next pandemic influenza, epidemiological surveillance of animal and avian influenza viruses was p ...

Research Products of this project	Journal Article (44 results) Publications (24 results)

17. Molecular basis for highly pathogenesis of avian influenza virus in humans.

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Virology
Research Institution	The University of Tokyo
Principal Investigator	KAWAOKA Yoshihiro The University of Tokyo, IMS, Professor
Project Period (FY)	2000 – 2002Completed
Keywords	avian influenza virus / H5N1 / reverse genetics
Research Abstract	Influenza is an example of a disease for which the viral pathogen has emerged into the human population many times over past centuries, sometimes with ...

Research Products of this project	Journal Article (10 results) Publications (12 results)

Project Period (Start Year [FY])

1. ネオウイルス学：生命の源流から超個体、そしてエコ・スフィアーへ Compiling the Research Achievements

河岡 義裕 東京大学, 医科学研究所, 特任教授

2. Surveillance of viruses causing zoonotic infections across three continents Research Project

河岡 義裕 東京大学, 医科学研究所, 特任教授

3. Neo-virology: the raison d'etre of viruses Research Areas

河岡 義裕 東京大学, 医科学研究所, 特任教授

4. Neo-virology: the raison d'etre of viruses International Activities Supporting Group

Kawaoka Yoshihiro 東京大学, 医科学研究所, 特任教授

5. Symbiotic Relationship between Influenza Virus and Waterfowl in Nature Planned Research

Watanabe Tokiko 大阪大学, 微生物病研究所, 教授

6. Neo-virology: the raison d'etre of viruses Administrative Group

Kawoaka Yoshihiro 東京大学, 医科学研究所, 特任教授

7. インフルエンザウイルスのゲノムパッケージング機構の解明 Research Project

河岡 義裕 東京大学, 医科学研究所, 教授

8. 新型インフルエンザウイルスの出現機構とその制圧 Research Project

河岡 義裕 東京大学, 医科学研究所, 教授

9. Mechanism of emergence of new influenza viruses and their control Research Project

KAWAOKA Yoshihiro 東京大学, 医科学研究所, 教授

10. Ecology and pandemic planning of animal influenza virus Research Project

KIDA Hiroshi Hokkaido University, Graduate School of Veterinary Medicine, Professor

11. Influenza virus : the mechanism of genome packaging Research Project

KAWAOKA Yoshihiro University of Tokyo, Institute of Medical Science, Professor

12. 半生インフルエンザウイルスベクターの開発 Research Project

河岡 義裕 東京大学, 医科学研究所, 教授

13. Development of influenza live vaccine by reverse genetics Research Project

KAWAOKA Yoshihiro University of Tokyo, IMS, Professor

14. Study on development of a live attenuated vaccine for equine influenza infection using reverse genetics Research Project

GOTO Hideo The University of Tokyo, Institute of Medical Science, Research Associate

15. インフルエンザウイルス:ゲノム・パッケージングのメカニズム Research Project

河岡 義裕 東京大学, 医科学研究所, 教授

16. Ecological study of animal influenza viruses : To prepare for the emergence of pandemic influenza Research Project

KIDA Hiroshi Hokkaido University, Hokkaido University, Graduate School of Veterinary Medicine, Professor

17. Molecular basis for highly pathogenesis of avian influenza virus in humans. Research Project

KAWAOKA Yoshihiro The University of Tokyo, IMS, Professor

1. ネオウイルス学：生命の源流から超個体、そしてエコ・スフィアーへ

Compiling the Research Achievements

河岡義裕東京大学, 医科学研究所, 特任教授

2. Surveillance of viruses causing zoonotic infections across three continents

Research Project

河岡義裕東京大学, 医科学研究所, 特任教授

3. Neo-virology: the raison d'etre of viruses

Research Areas

河岡義裕東京大学, 医科学研究所, 特任教授

4. Neo-virology: the raison d'etre of viruses

International Activities Supporting Group

5. Symbiotic Relationship between Influenza Virus and Waterfowl in Nature

Planned Research

6. Neo-virology: the raison d'etre of viruses

Administrative Group

7. インフルエンザウイルスのゲノムパッケージング機構の解明

Research Project

河岡義裕東京大学, 医科学研究所, 教授

8. 新型インフルエンザウイルスの出現機構とその制圧

Research Project

河岡義裕東京大学, 医科学研究所, 教授

9. Mechanism of emergence of new influenza viruses and their control

Research Project

10. Ecology and pandemic planning of animal influenza virus

Research Project

11. Influenza virus : the mechanism of genome packaging

Research Project

12. 半生インフルエンザウイルスベクターの開発

Research Project

河岡義裕東京大学, 医科学研究所, 教授

13. Development of influenza live vaccine by reverse genetics

Research Project

14. Study on development of a live attenuated vaccine for equine influenza infection using reverse genetics

Research Project

15. インフルエンザウイルス:ゲノム・パッケージングのメカニズム

Research Project

河岡義裕東京大学, 医科学研究所, 教授

16. Ecological study of animal influenza viruses : To prepare for the emergence of pandemic influenza

Research Project

17. Molecular basis for highly pathogenesis of avian influenza virus in humans.

Research Project