KAKEN — Research Projects | Researcher Number: 10037385

Search Results: 16 results / Researcher Number: 10037385

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1. Toward an elucidation of transmission mechanisms and pathological conditions of leishmaniasis

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Parasitology (including sanitary zoology)
Research Institution	Jichi Medical University (2016-2017) Hokkaido University (2013-2015)
Principal Investigator	KATO Hirotomo 自治医科大学, 医学部, 教授
Project Period (FY)	2013-04-01 – 2017-03-31Completed
Keywords	リーシュマニア症 / リーシュマニア原虫 / ベクター / サシチョウバエ / リザーバー / 分子疫学 / 血清診断 / エクアドル / ペルー / タイ / リーシュマニア / 疫学 / 診断
Outline of Final Research Achievements	Countrywide epidemiological study on leishmaniasis was performed using FTA cards as a sample collection tool, and causative parasite species as well a ...

Research Products of this project	Int'l Joint Research (3 results) Journal Article (31 results, of which Int'l Joint Research: 12 results, Peer Reviewed: 30 results, Open Access: 4 results, Acknowledgement Compliant: 6 results) Presentation (26 results, of which Int'l Joint Research: 1 results, Invited: 4 results)

2. Molecular epidemiology and pathobiology of New World leishmaniases

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Parasitology (including Sanitary zoology)
Research Institution	Kochi University
Principal Investigator	HASHIGUCHI YOSHIHISA 高知大学, その他部局等, 名誉教授
Project Period (FY)	2011-04-01 – 2015-03-31Completed
Keywords	国際交流研究 / エクアドル：ペルー：アルゼンチン / リーシュマニア症 / 媒介サシチョウバエ / 伝播疫学 / 分子生物学 / 病態生理 / Leishmania原虫感染 / エクアドル / ペルー / リーシュマニア原虫 / サシチョウバエ / 遺伝子解析 / 分子疫学 / 原虫感染症 / ペル- / リ-シュマニア症 / ロ-ション / 局所療法 / ペル‐ / リ－シュマニア症 / ロ－ション / 国際研究者交流 / エクアドル:ペルー:アルゼンチン:ベネズエラ / FTAカード
Outline of Final Research Achievements	Leishmaniasis is one of the protozoan infectious diseases transmitted by blood-sucking insects, sandflies. The disease is widely distributed, affectin ...

Research Products of this project	Journal Article (41 results, of which Peer Reviewed: 38 results, Open Access: 6 results, Acknowledgement Compliant: 11 results) Presentation (33 results, of which Invited: 9 results) Book (1 results)

3. Basic and applied studies for early diagnosis and early treatment of visceral leishmaniasis

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Parasitology (including Sanitary zoology)
Research Institution	Aichi Medical University
Principal Investigator	ITOH Makoto Aichi Medical University
Project Period (FY)	2006 – 2008Completed
Keywords	内臓リーシュマニア症 / 診断 / 尿 / バングラデシュ / LAMP / 国際研究者交流 / リーシュマニア症 / 免疫診断 / 尿検体 / LAMP法
Research Abstract	(1)内臓リーシュマニア症(VL症)の早期発見のための診断法を開発した。尿を用いた免疫診断法と、原虫由来DNAを検出する遺伝子診断法(LAMP法)である。バングラデシュ・マメンシン地区の4,800人の調査から、この地区では年間約7%の住民がLeishmania原虫の感染を受け、その約半数がVL症を発 ...

Research Products of this project	Journal Article (24 results, of which Peer Reviewed: 18 results) Presentation (22 results)

4. Studies on the transmission and pathobiology of New and Old World leishmaniases

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	Parasitology (including Sanitary zoology)
Research Institution	Kochi University
Principal Investigator	HASHIGUCHI Yoshihisa Kochi University
Project Period (FY)	2006 – 2009Completed
Keywords	国際交流研究 / エクアドル:ペルー:アルゼンチン:パキスタン:バングラデシュ / リーシュマニア症 / 媒介サシチョウバエ / 伝播疫学 / 分子生物学 / 病態生理 / Leishmania原虫感染 / 国際研究者交流 / エクアドル:ペルー:パキスタン:バングラデシュ / サシチョウバエ / リーシュマニア原虫 / LAMP法 / エクアドル / ペルー / アルゼンチン / パキスタン / バングラデシュ / ウタ症 / バルトネラ症 / アマスチゴート抗原 / ONO-4007
Research Abstract	Leishmaniasis is one of the protozoan infectious diseases transmitted by blood-sucking insects, sandflies. The disease is widely distributed, affectin ...

Research Products of this project	Journal Article (59 results, of which Peer Reviewed: 48 results) Presentation (23 results) Book (8 results)

5. Basic and applied research for early diagnosis and early treatment of visceral leishmaniasis

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Parasitology (including Sanitary zoology)
Research Institution	Aichi Medical University School of Medicine
Principal Investigator	ITOH Makoto Aichi Medical University School of Medicine, Department of Parasitology, Associate Professor
Project Period (FY)	2003 – 2005Completed
Keywords	leishmaniasis / Immunodiagnosis / urine / recombinant protein / Bangladesh / sandfly / international collaboration / GPS
Research Abstract	The aim of this study was to develop simple diagnostic tools for visceral leishmaniasis (VL) using urine samples for early diagnosis and early treatme ...

Research Products of this project	Journal Article (25 results) Book (3 results) Publications (7 results)

6. Differential function of antigen-presenting cells induced by IL-3 in host protective immunity against Trichinella spiralis infection

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	寄生虫学(含医用動物学)
Research Institution	Kochi University(Medical School)
Principal Investigator	KORENAGA Masataka Kochi University(Medical School), Associate professor
Project Period (FY)	2002 – 2003Completed
Keywords	Trichinella spiralis / IL-3 / IL-4 / IL-10 / IL-2 / CD11b+ cells / protective immunity
Research Abstract	We have reported that both Th2 responses and protective immunity were accelerated in mice treated with rIL-3 after an infection of Trichinella spirali ...

Research Products of this project	Publications (6 results)

7. Pathophysiological studies on the New and Old World leishmaniases and their transmission

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	寄生虫学(含医用動物学)
Research Institution	Kochi Univerfsity
Principal Investigator	HASHIGUCHI Yoshihisa KOCHI UNIVERSITY, MEDICAL SCHOOL, PROFESSOR
Project Period (FY)	2002 – 2005Completed
Keywords	leishmaniasis / Ecuador / Argentina / Pakistan / transmission / pathobiology / amastigote-antigen / ONO-4007
Research Abstract	The following findings on the pathobiology and transmission on the New and Old World leishmaniases were obtained from Ecuador, Argentina and Pakistan, ...

Research Products of this project	Journal Article (69 results) Book (11 results) Publications (15 results)

8. 節足動物媒介性疾患及び媒介動物の防圧戦略と研究者ネットワークの構築

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	寄生虫学(含医用動物学)
Research Institution	Mie University
Principal Investigator	鎮西康雄三重大学, 医学部, 教授
Project Period (FY)	2000Completed
Keywords	節足動物媒介性疾患 / ベクター / 新興・再興感染症 / アルボウイルス / 熱帯病
Research Abstract	本企画研究ではこれまで国内で個別に行われてきた媒介動物とその感染症の研究者を発掘し、協力体制を整え、組織的計画的に研究を進めるための予備的な調査と組織化を目的として、班会議、研究集会、国際シンポジウムを企画し、将来の特別領域研究発足を視野に入れた企画を実行した。

9. A study on protective immunity in mice infected with Trichinella spiralis : A new role of IL-3 as Th2 amplifier in immune response to parasite infection

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	寄生虫学(含医用動物学)
Research Institution	Kochi Medical School
Principal Investigator	KORENAGA Masataka Faculty of Medicine, Department of Parasitology, Associate Professor
Project Period (FY)	1998 – 2000Completed
Keywords	Trichinella spiralis / Th2 responses / IL-3 / IL-4 / Protective immunity / Mast cells / aly mouse / Nuclear factor inducing kinase
Research Abstract	Cytokine balance is a key factor for the generation of protective immunity and pathology in nematode infections. Infection with Trichinella spiralis e ...

Research Products of this project	Publications (6 results)

10. Studies on leishmaniasis and its transmission in Central and South Americas

Research Project

Research Category	Grant-in-Aid for Scientific Research (A).
Research Field	寄生虫学(含医用動物学)
Research Institution	Kochi Medical School
Principal Investigator	HASHIGUCHI Yoshihisa Kochi Medical School, Parasitology, Prof.
Project Period (FY)	1998 – 2000Completed
Keywords	cutaneous leishmaniasis / Ecuador / PCR / diagnosis / treatment / Leishmania / Lutzomyia / sandfly
Research Abstract	In order to have an information on the New World leishmaniasis, especially in Ecuador, an intensive study has been done from the multidisciplinary vie ...

Research Products of this project	Publications (32 results)

11. Studies on New World leishmaniasis and its transmission

Research Project

Research Category	Grant-in-Aid for international Scientific Research
Research Field	寄生虫学(含医用動物学)
Research Institution	Kochi Medical School
Principal Investigator	HASHIGUCHI Yoshihisa Kochi Medical School, Parasitology, Professor
Project Period (FY)	1996 – 1997Completed
Keywords	Ecuador / Cutaneous leishmaniasis / Mephaquin / Artesunate / Treatment / Oral treatment / Skin biopsy / Patients
Research Abstract	In Ecuador, a leishmaniasis project entitled "Studies on New World leishmaniasis and its transmission, with particular refernce to Ecuador" has been c ...

Research Products of this project	Publications (42 results)

12. Examination of drugs effective for Ieishmaniasis

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	寄生虫学(含医用動物学)
Research Institution	Kochi Medical School
Principal Investigator	HASHIGUCHI Yoshihisa Kochi Medical School, Parasitology, Professor
Project Period (FY)	1995 – 1997Completed
Keywords	antimalarial drug / Mephaquin / Artesunate / antileishmanial drug / cutaneous leishmaniasis / PCR / nucleotide sequence / electron-microscopic pathology
Research Abstract	In leishmaniasis, antimonials such as Glucantime and Pentostum are the first choice of treatment for a wide range of clinical forms of the disease in ...

Research Products of this project	Publications (40 results)

13. Studies on New World leishmaniasis and its transmission

Research Project

Research Category	Grant-in-Aid for international Scientific Research
Research Institution	Kochi Medical School
Principal Investigator	HASHIGUCHI Yoshihisa Kochi Medical School, Faculty of Medicine, Professor
Project Period (FY)	1993 – 1995Completed
Keywords	Ecuador / Cutaneous leishmaniasis / Patients / Mephaquin / Plasmotrim / Experimental animals / Oral treatment / Skin biopsy / Antimalarial drugs
Research Abstract	In this fiscal year, the following items were mainly carried out : 1) the treatment of cutaneous leishmaniasis patients with antimalarial drugs ; 2) i ...

Research Products of this project	Publications (29 results)

14. Studies on New World leishmaniasis and its transmisson

Research Project

Research Category	Grant-in-Aid for international Scientific Research
Research Institution	Kochi Medical School
Principal Investigator	HASHIGUCHI Yoshihisa Department of Parasitology, Kochi Medical School, Kochi, Japan
Project Period (FY)	1990 – 1992Completed
Keywords	Leishmaniasis / Vector sandflies / Reservoir hosts / Leishmania parastites / Dermal lesions / Treatment / Molecular boilogy / Ecuador
Research Abstract	In this fiscal year (1992), the data obtained were analyzed from the view of parasitological, immunological, molecular biological, clinical and pathol ...

Research Products of this project	Publications (31 results)

15. Studies on New World leishmaniasis and its transmission

Research Project

Research Category	Grant-in-Aid for Overseas Scientific Survey.
Research Institution	Kochi Medical School
Principal Investigator	HASHIGUCHI Yoshihisa Department of Parasitology Kochi Medical School, Kochi, Japan
Project Period (FY)	1988 – 1989Completed
Keywords	Leishmaniasis / Sandflies / Rreservoirs / Epidemiology / Skin test
Research Abstract	In the present study, American cutaneous and mucocutaneous leishmaniasis was examined. The results obtained are summarized as follows. ...

Research Products of this project	Publications (12 results)

16. Studies on New World leishmaniasis and its transmission

Research Project

Research Category	Grant-in-Aid for Overseas Scientific Research
Research Institution	Kochi Medical School
Principal Investigator	HASHIGUCHI Yoshihisa Department of Parasitology, Kochi Medical School, Dochi, Japan
Project Period (FY)	1986 – 1987Completed
Keywords	Leishmaniasis / sandflies / reservoirs / Leishmania isolates / Transmission / Epidemiological surveys / Skin test
Research Abstract	In order to elucidate epidemiological features of leishmaniasis in Centeal and South Americas, field studies on several aspects of the disease were pe ...

Research Products of this project	Publications (10 results)