KAKEN — Research Projects | Researcher Number: 00292277

1. Transcranial Whole Brain Imaging by Microwave-induced Thermoacoustics

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Review Section	Basic Section 90130:Medical systems-related Basic Section 90140:Medical technology assessment-related Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
Research Institution	Tohoku University
Principal Investigator	西條芳文東北大学, 医工学研究科, 教授
Project Period (FY)	2023-04-01 – 2026-03-31Granted
Keywords	熱音響イメージング / 経頭蓋イメージング / マイクロ波
Outline of Research at the Start	医学的・社会的に重要な課題である脳卒中の治癒経過を従来のfMRIやPETなどのマクロレベルだけではなく、細胞レベルでも観察できるマルチスケールなイメージングが期待されている。光音響イメージングはごく短時間の強力パルス光照射による組織の熱膨張で発生する光音響波に基づき細胞レベルのイメージングを可能にす ...

2. ジラジカル錯体をがん認識光熱変換プローブとするがんの未来型セラノスティクス

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Review Section	Basic Section 34020:Analytical chemistry-related
Research Institution	Tohoku University
Principal Investigator	壹岐伸彦東北大学, 環境科学研究科, 教授
Project Period (FY)	2022-04-01 – 2025-03-31Granted
Keywords	セラノスティクス / プローブ / イメージング / ジラジカル錯体 / 白金錯体 / 近赤外光 / 光音響イメージング / 光熱治療 / 光熱変換プローブ / ミセル / 葉酸 / 金属錯体 / 近赤外吸収 / 光熱療法
Outline of Research at the Start	生体透過性の高い近赤外(NIR)光を強く吸収し，高効率に光熱変換するジラジカルPt(II)錯体をがん細胞に送達できれば，がんの光音響(PA)イメージング(PAI)と光熱治療(PTT)とを組み合わせた，セラノスティクスにつながる．本研究ではジラジカル錯体を基に，生体中で安定で，がんに選択的に送達され， ...
Outline of Annual Research Achievements	本年度は次の①から③を重点的に検討し，それぞれ成果を得た．
Current Status of Research Progress	2: Research has progressed on the whole more than it was originally planned.

Research Products of this project	Journal Article (5 results, of which Peer Reviewed: 5 results) Presentation (13 results, of which Invited: 1 results) Remarks (1 results)

3. Development of 3D acoustic CT with multi-channel phonocardiogram for lung lesion detection

Research Project

Research Category	Grant-in-Aid for Challenging Research (Exploratory)
Review Section	Medium-sized Section 90:Biomedical engineering and related fields
Research Institution	Tohoku University
Principal Investigator	Saijo Yoshifumi 東北大学, 医工学研究科, 教授
Project Period (FY)	2021-07-09 – 2024-03-31Completed
Keywords	心音図 / 音響CT / 新型コロナウイルス / 肺
Outline of Research at the Start	特別な設備・技術を要さずに安全・簡便に施行でき、かつX線CT検査に匹敵する局所病変検出能のある肺のイメージング手法は、新型コロナウイルス感染のみならず、高齢化社会における老健施設や在宅介護における誤嚥性肺炎の早期診断法としてもその適用範囲は広い。本研究では、心臓で発生した心音を体表に装着した多数の心 ...
Outline of Final Research Achievements	A multichannel heart sound measurement system was developed. Heart sound from a point sound source in the heart passes through the surrounding lung pa ...

Research Products of this project	Journal Article (3 results, of which Int'l Joint Research: 1 results, Peer Reviewed: 3 results, Open Access: 2 results) Remarks (1 results)

4. Ultrasonic signed echo imaging to distinguish bwtween vulnerable and stable plaques

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Review Section	Basic Section 90130:Medical systems-related
Research Institution	Tohoku University
Principal Investigator	Umemura Shin-ichiro 東北大学, 医工学研究科, 学術研究員
Project Period (FY)	2021-04-01 – 2024-03-31Completed
Keywords	符号付きエコー像 / 基本波 / 2倍周波 / 不安定プラーク / 2Dアレイプローブ / 基本周波 / 安定プラーク / 2Dアレイ・プローブ / 音響インピーダンス / 反射エコー / 第2高調波 / アレイ受信器 / 位相検出 / 有限要素法 / 反射体モデル / 超音波イメージング / 符号付きエコー / 1.5Dアレイプローブ
Outline of Research at the Start	動脈硬化症をクリーニングするにあたり，頸動脈エコー検査は，有効であり広く用いられている．そこで発見されるプラークについて，それが不安定性であるか否かを判別することは，治療方針を決定するにあたってきわめて重要である．頸動脈の不安定プラークは，それが破綻して脳梗塞を直接引き起こす危険性があるだけでなく， ...
Outline of Final Research Achievements	The purpose of this study is to distinguish reflectors with acoustic impedances lower and higher than the surrounding medium, which correspond to unst ...

Research Products of this project	Journal Article (12 results, of which Peer Reviewed: 12 results, Open Access: 1 results) Presentation (3 results, of which Int'l Joint Research: 3 results)

5. Evaluation of soft tissue sarcoma reaction layer using arc-type photoacoustic transducer

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Review Section	Basic Section 56020:Orthopedics-related
Research Institution	Tohoku University
Principal Investigator	Watanuki Munenori 東北大学, 医学系研究科, 非常勤講師
Project Period (FY)	2021-04-01 – 2024-03-31Completed
Keywords	骨軟部肉腫 / 軟部肉腫 / アーク型光音響トランスデューサー
Outline of Research at the Start	「光音響イメージング」は物質にレーザー光を照射する時に発生する超音波を検出することで従来の超音波イメージングより優れた解像度で生体組織内部を描出することができる。本研究では①指用に開発されたアーク型光音響トランスデューサーを用いたラット脂肪組織炎症モデルでの計測、②同装置を使用した軟部肉腫組織の計測 ...
Outline of Final Research Achievements	Soft tissue sarcoma is a non-epithelial malignant tumor that occurs in soft tissue, and the standard treatment is wide excision, which involves removi ...

6. Development of photoacoustic endoscope using wideband microarray for advanced intraoperative vascularity diagnosis

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Review Section	Medium-sized Section 90:Biomedical engineering and related fields
Research Institution	Shibaura Institute of Technology
Principal Investigator	椎名毅芝浦工業大学, 工学(系)研究科(研究院), 教授
Project Period (FY)	2021-04-05 – 2025-03-31Granted
Keywords	光超音波イメージング / 内視鏡 / がん診断 / 可視化 / 内視鏡・腹腔鏡下手術 / 術中診断支援
Outline of Research at the Start	内視鏡下や腹腔鏡下手術は、患者負担が少なく術後回復の早い点で、がんの外科的治療法の有力選択肢となっているが、カメラ画像による内視鏡は組織表面の観察であり深部への癌の進展や良悪性の鑑別は困難である。本研究は、光超音波イメージングの先進技術を導入した光超音波内視鏡システムを開発し、それにより術中にリアル ...
Outline of Annual Research Achievements	本研究は、低侵襲性が利点で適用が進んでいる内視鏡や腹腔鏡下の手術において、精度の高い治療を行う上で必要とされる術中の診断情報を、現状のシステムでは十分に獲得できていないという課題を解決するため、光超音波イメージングの先進技術を導入することで、術中での腫瘍良悪性の鑑別、がん浸潤範囲、リンパ節転移等の診 ...
Current Status of Research Progress	3: Progress in research has been slightly delayed.

Research Products of this project	Journal Article (28 results, of which Int'l Joint Research: 6 results, Peer Reviewed: 23 results, Open Access: 14 results) Presentation (35 results, of which Int'l Joint Research: 2 results, Invited: 6 results) Book (2 results)

7. Development of transcranical four-dimensional ultrasound imaging

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Review Section	Basic Section 90130:Medical systems-related
Research Institution	Tohoku University
Principal Investigator	Saijo Yoshifumi 東北大学, 医工学研究科, 教授
Project Period (FY)	2020-04-01 – 2023-03-31Completed
Keywords	超音波 / 経頭蓋 / ４次元 / マウス / 微小血流 / 4次元 / 微小血管 / 脳
Outline of Research at the Start	脳の病態生理解明には、CT、MRI、PETなど既存の医用イメージングに加えて、高空間＋高時間分解能とリアルタイム性を実現した手法が必要である。これらの条件をすべて備えた超音波は新たな脳機能診断モダリティーとなることが期待されるが、従来は頭蓋骨における超音波の減衰や屈折により脳の微細構造および微小血流 ...
Outline of Final Research Achievements	In order to observe the micro blood flow in the mouse brain through the skull, we developed three-dimensional imaging using a low-frequency hemispheri ...

Research Products of this project	Journal Article (6 results, of which Int'l Joint Research: 4 results, Peer Reviewed: 6 results, Open Access: 6 results) Presentation (3 results, of which Int'l Joint Research: 3 results, Invited: 1 results) Remarks (1 results)

8. Basic study on high-accuracy acoustic property measurements of biological specimens by ultrasonic microscopy

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Review Section	Basic Section 21030:Measurement engineering-related
Research Institution	Tohoku University
Principal Investigator	ARAKAWA Mototaka 東北大学, 医工学研究科, 准教授
Project Period (FY)	2018-04-01 – 2021-03-31Completed
Keywords	計測工学 / 超音波顕微鏡 / 音速 / 厚さ / 生体試料 / 集束超音波
Outline of Final Research Achievements	In this study, we proposed a robust analysis method for the acoustic properties of biological specimens measured by acoustic microscopy. To obtain the ...

Research Products of this project	Journal Article (13 results, of which Peer Reviewed: 13 results) Presentation (27 results, of which Int'l Joint Research: 6 results) Remarks (5 results)

9. Innovative theranostics system with magnetic carbon nanotube

Research Project

Research Category	Grant-in-Aid for Challenging Research (Exploratory)
Research Field	Biomedical engineering and related fields
Research Institution	Tohoku University
Principal Investigator	Saijo Yoshifumi 東北大学, 医工学研究科, 教授
Project Period (FY)	2017-06-30 – 2019-03-31Completed
Keywords	セラノスティクス / カーボンナノチューブ / 光音響イメージング / 温熱治療
Outline of Final Research Achievements	The basis of innovative theranostics system with magnetic carbon nanotube (M-CNT) was investigated. In the diagnostic side, M-CNT for photoacoustic (P ...

Research Products of this project	Journal Article (6 results, of which Int'l Joint Research: 2 results, Peer Reviewed: 6 results, Open Access: 2 results) Presentation (5 results, of which Int'l Joint Research: 5 results, Invited: 5 results) Remarks (2 results)

10. Research and developments on next-generation harmonic ultrafast ultrasound imaging for accurate analysis of cardiovascular dynamics

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Measurement engineering
Research Institution	University of Toyama
Principal Investigator	Hasegawa Hideyuki 富山大学, 学術研究部工学系, 教授
Project Period (FY)	2017-04-01 – 2020-03-31Completed
Keywords	超音波 / 積層振動子 / 高速イメージング / 積層型振動子
Outline of Final Research Achievements	Cardiovascular diseases are the significant causes of mortality in Japan. Methods for the measurement of the cardiovascular dynamics are required to e ...

Research Products of this project	Journal Article (19 results, of which Peer Reviewed: 19 results) Presentation (106 results, of which Int'l Joint Research: 30 results, Invited: 13 results) Book (1 results) Remarks (3 results)

11. Cancer theranostics using near-infrared absorbing metal complex as a photothermal probe

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Analytical chemistry
Research Institution	Tohoku University
Principal Investigator	Iki Nobuhiko 東北大学, 環境科学研究科, 教授
Project Period (FY)	2017-04-01 – 2020-03-31Completed
Keywords	セラノスティクス / プローブ / 近赤外光 / 白金錯体 / 光音響イメージング / 光熱治療 / ラジカル / がん / イメージング / 光熱療法 / 近赤外吸収プローブ / ジラジカル / デリバリー / スイッチング / ラジカル配位子 / 光熱変換 / 分析試薬 / 金属錯体 / 近赤外プローブ / 分子プローブ
Outline of Final Research Achievements	We studied functions of a series of Pt(II)-diradical complexes aimed at application to a probe for theranostics of cancer to provide accurate but affo ...

Research Products of this project	Journal Article (8 results, of which Peer Reviewed: 6 results, Open Access: 4 results) Presentation (45 results, of which Int'l Joint Research: 8 results, Invited: 7 results) Remarks (1 results)

12. Development of 3D photoacoustic CT with arc tran sducer for finger joint

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Medical systems
Research Institution	Tohoku University
Principal Investigator	Saijo Yoshifumi 東北大学, 医工学研究科, 教授
Project Period (FY)	2017-04-01 – 2020-03-31Completed
Keywords	光音響イメージング / 関節リウマチ / 酸素飽和度 / 微小血管 / 慢性関節リウマチ / 高性能レーザー
Outline of Final Research Achievements	Principles of 3D photoacoustic CT were investigated in order to evaluate inflammatory activity of finger joints in rheumatoid arthritis visualized wit ...

Research Products of this project	Journal Article (8 results, of which Int'l Joint Research: 2 results, Peer Reviewed: 8 results, Open Access: 2 results) Presentation (7 results, of which Int'l Joint Research: 6 results, Invited: 7 results) Remarks (4 results)

13. Development of a novel quantitative blood flow sensor for single ventricle disease newborns

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Cardiovascular surgery
Research Institution	Tohoku University
Principal Investigator	Sai Sadahiro 東北大学, 医学系研究科, 非常勤講師
Project Period (FY)	2016-04-01 – 2019-03-31Completed
Keywords	超小型血流測定器 / 体内留置 / 非鉛セラミック / 血流測定装置 / 肺体血流比 / 先天性心疾患 / ピエゾ現象 / 超音波血流計 / 単心室疾患
Outline of Final Research Achievements	Despite the recent improvement in the understanding of pathophysiology and the management of the perioperative neonate, the morbidity and mortality ra ...

14. Development of photoacoustic flow cytometry by employing multi-channel high frequency ultrasonic probe

Research Project

Research Category	Grant-in-Aid for Research Activity Start-up
Research Field	Medical systems
Research Institution	University of Toyama (2017) Tohoku University (2016)
Principal Investigator	Nagaoka Ryo 富山大学, 工学部, 特命助教
Project Period (FY)	2016-08-26 – 2018-03-31Completed
Keywords	超音波計測 / 光音響スペクトロスコピー計測 / 多チャンネル高周波数超音波プローブ / 計測工学 / 光音響計測 / 高周波数超音波プローブ / 光音響波イメージング
Outline of Final Research Achievements	In a traditional photoacoustic flow cytometry, cells in vessels are aligned in one line by laser manipulation, and the photoacoustic signals induced f ...

Research Products of this project	Journal Article (3 results, of which Peer Reviewed: 3 results, Open Access: 1 results) Presentation (8 results, of which Int'l Joint Research: 1 results, Invited: 1 results) Patent(Industrial Property Rights) (1 results)

15. Advanced human thermophysiological model for evaluating health risks due to thermal environments

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Architectural environment/Equipment
Research Institution	Tohoku University
Principal Investigator	GOTO TOMONOBU 東北大学, 工学研究科, 准教授
Project Period (FY)	2016-04-01 – 2019-03-31Completed
Keywords	建築環境・設備 / 温熱生理 / 人体シミュレーション / 体温 / 血圧 / 血流量 / 熱中症 / ヒートショック
Outline of Final Research Achievements	In order to establish a new human thermophysiological model which can predict not only body temperature but also blood pressure and blood flow rate, w ...

Research Products of this project	Presentation (10 results, of which Int'l Joint Research: 2 results)

16. Estimation of three-dimensional blood flow vector by super-harmonic echocardiography

Research Project

Research Category	Grant-in-Aid for Challenging Exploratory Research
Research Field	Cardiovascular medicine
Research Institution	Tohoku University
Principal Investigator	SAIJO Yoshifumi 東北大学, 医工学研究科, 教授
Project Period (FY)	2015-04-01 – 2017-03-31Completed
Keywords	超音波 / 血流ベクトル / 2次元 / 3次元 / 超音波ドプラ法 / スーパーハーモニック
Outline of Final Research Achievements	A broadband sector ultrasound probe with 64 elements was developed and ultrasound was emitted and received by a programmable ultrasound RF signal proc ...

Research Products of this project	Journal Article (3 results, of which Peer Reviewed: 3 results) Presentation (3 results, of which Int'l Joint Research: 1 results) Remarks (1 results)

17. Intra-operative imaging of soft tissue sarcoma with photoacoustic imaging

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Orthopaedic surgery
Research Institution	Tohoku University
Principal Investigator	Watanuki Munenori 東北大学, 大学病院, 講師
Project Period (FY)	2015-04-01 – 2018-03-31Completed
Keywords	軟部肉腫 / 光音響顕微鏡 / 光音響効果 / ヌードマウス / 担癌マウス / IR780 / イメージング装置 / MG63 / 肉腫モデルマウス / 蛍光イメージング / 光音響顕微鏡装置 / 術中イメージング
Outline of Final Research Achievements	Surgery of soft tissue sarcoma is wide resection, which means macroscopically and microscopically complete sarcoma resection with reactive layer and n ...

18. Atrial natriuretic peptide induces peroxisome proliferator

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Cardiovascular surgery
Research Institution	Tohoku University
Principal Investigator	Kawamoto Shunsuke 東北大学, 医学系研究科, 非常勤講師
Project Period (FY)	2015-04-01 – 2018-03-31Completed
Keywords	心筋虚血再灌流 / ANP / PPARγ / 心筋虚血再灌流障害 / hANP
Outline of Final Research Achievements	Atrial natriuretic peptide is a cardiac atriumderived hormone and its cardioprotective effects have recently been confirmed, but the actual mechanism ...

Research Products of this project	Journal Article (2 results, of which Peer Reviewed: 1 results, Open Access: 1 results)

19. Non-invasive visco-elastic imaging for living cells by ultrasound

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Measurement engineering
Research Institution	Toyohashi University of Technology
Principal Investigator	Hozumi Naohiro 豊橋技術科学大学, 工学(系)研究科(研究院), 教授
Project Period (FY)	2015-04-01 – 2018-03-31Completed
Keywords	超音波顕微鏡 / 生体細胞 / 粘弾性イメージング
Outline of Final Research Achievements	In this study, we developed an observatoin system that displays quantitatively and continuously the cultured cells continuously and non-invasively usi ...

Research Products of this project	Journal Article (10 results, of which Int'l Joint Research: 1 results, Peer Reviewed: 10 results, Open Access: 5 results) Presentation (23 results, of which Int'l Joint Research: 8 results, Invited: 1 results) Book (1 results) Remarks (2 results)

20. Clarification of fluid dynamical effect of near-wall flow field on enrtherial cell damage by measurement-integrated-simulation

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Fluid engineering
Research Institution	Tohoku University
Principal Investigator	Hayase Toshiyuki 東北大学, 流体科学研究所, 教授
Project Period (FY)	2015-04-01 – 2018-03-31Completed
Keywords	バイオ流体力学 / 計測融合シミュレーション
Outline of Final Research Achievements	It is known that damage on endothelial cells on the surface of a blood vessel causes diseases of blood vessels such as atherosclerosis or aneurisms. H ...

Research Products of this project	Journal Article (3 results, of which Peer Reviewed: 3 results, Open Access: 2 results, Acknowledgement Compliant: 3 results) Presentation (20 results, of which Int'l Joint Research: 7 results)

Project Period (Start Year [FY])

1. Transcranial Whole Brain Imaging by Microwave-induced Thermoacoustics Research Project

西條 芳文 東北大学, 医工学研究科, 教授

2. ジラジカル錯体をがん認識光熱変換プローブとするがんの未来型セラノスティクス Research Project

壹岐 伸彦 東北大学, 環境科学研究科, 教授

3. Development of 3D acoustic CT with multi-channel phonocardiogram for lung lesion detection Research Project

Saijo Yoshifumi 東北大学, 医工学研究科, 教授

4. Ultrasonic signed echo imaging to distinguish bwtween vulnerable and stable plaques Research Project

Umemura Shin-ichiro 東北大学, 医工学研究科, 学術研究員

5. Evaluation of soft tissue sarcoma reaction layer using arc-type photoacoustic transducer Research Project

Watanuki Munenori 東北大学, 医学系研究科, 非常勤講師

6. Development of photoacoustic endoscope using wideband microarray for advanced intraoperative vascularity diagnosis Research Project

椎名 毅 芝浦工業大学, 工学(系)研究科(研究院), 教授

7. Development of transcranical four-dimensional ultrasound imaging Research Project

Saijo Yoshifumi 東北大学, 医工学研究科, 教授

8. Basic study on high-accuracy acoustic property measurements of biological specimens by ultrasonic microscopy Research Project

ARAKAWA Mototaka 東北大学, 医工学研究科, 准教授

9. Innovative theranostics system with magnetic carbon nanotube Research Project

Saijo Yoshifumi 東北大学, 医工学研究科, 教授

10. Research and developments on next-generation harmonic ultrafast ultrasound imaging for accurate analysis of cardiovascular dynamics Research Project

Hasegawa Hideyuki 富山大学, 学術研究部工学系, 教授

11. Cancer theranostics using near-infrared absorbing metal complex as a photothermal probe Research Project

Iki Nobuhiko 東北大学, 環境科学研究科, 教授

12. Development of 3D photoacoustic CT with arc tran sducer for finger joint Research Project

Saijo Yoshifumi 東北大学, 医工学研究科, 教授

13. Development of a novel quantitative blood flow sensor for single ventricle disease newborns Research Project

Sai Sadahiro 東北大学, 医学系研究科, 非常勤講師

14. Development of photoacoustic flow cytometry by employing multi-channel high frequency ultrasonic probe Research Project

Nagaoka Ryo 富山大学, 工学部, 特命助教

15. Advanced human thermophysiological model for evaluating health risks due to thermal environments Research Project

GOTO TOMONOBU 東北大学, 工学研究科, 准教授

16. Estimation of three-dimensional blood flow vector by super-harmonic echocardiography Research Project

SAIJO Yoshifumi 東北大学, 医工学研究科, 教授

17. Intra-operative imaging of soft tissue sarcoma with photoacoustic imaging Research Project

Watanuki Munenori 東北大学, 大学病院, 講師

18. Atrial natriuretic peptide induces peroxisome proliferator Research Project

Kawamoto Shunsuke 東北大学, 医学系研究科, 非常勤講師

19. Non-invasive visco-elastic imaging for living cells by ultrasound Research Project

Hozumi Naohiro 豊橋技術科学大学, 工学(系)研究科(研究院), 教授

20. Clarification of fluid dynamical effect of near-wall flow field on enrtherial cell damage by measurement-integrated-simulation Research Project

Hayase Toshiyuki 東北大学, 流体科学研究所, 教授

1. Transcranial Whole Brain Imaging by Microwave-induced Thermoacoustics

Research Project

西條芳文東北大学, 医工学研究科, 教授

2. ジラジカル錯体をがん認識光熱変換プローブとするがんの未来型セラノスティクス

Research Project

壹岐伸彦東北大学, 環境科学研究科, 教授

3. Development of 3D acoustic CT with multi-channel phonocardiogram for lung lesion detection

Research Project

4. Ultrasonic signed echo imaging to distinguish bwtween vulnerable and stable plaques

Research Project

5. Evaluation of soft tissue sarcoma reaction layer using arc-type photoacoustic transducer

Research Project

6. Development of photoacoustic endoscope using wideband microarray for advanced intraoperative vascularity diagnosis

Research Project

椎名毅芝浦工業大学, 工学(系)研究科(研究院), 教授

7. Development of transcranical four-dimensional ultrasound imaging

Research Project

8. Basic study on high-accuracy acoustic property measurements of biological specimens by ultrasonic microscopy

Research Project

9. Innovative theranostics system with magnetic carbon nanotube

Research Project

10. Research and developments on next-generation harmonic ultrafast ultrasound imaging for accurate analysis of cardiovascular dynamics

Research Project

11. Cancer theranostics using near-infrared absorbing metal complex as a photothermal probe

Research Project

12. Development of 3D photoacoustic CT with arc tran sducer for finger joint

Research Project

13. Development of a novel quantitative blood flow sensor for single ventricle disease newborns

Research Project

14. Development of photoacoustic flow cytometry by employing multi-channel high frequency ultrasonic probe

Research Project

15. Advanced human thermophysiological model for evaluating health risks due to thermal environments

Research Project

16. Estimation of three-dimensional blood flow vector by super-harmonic echocardiography

Research Project

17. Intra-operative imaging of soft tissue sarcoma with photoacoustic imaging

Research Project

18. Atrial natriuretic peptide induces peroxisome proliferator

Research Project

19. Non-invasive visco-elastic imaging for living cells by ultrasound

Research Project

20. Clarification of fluid dynamical effect of near-wall flow field on enrtherial cell damage by measurement-integrated-simulation

Research Project