Journal of Biological Chemistry
Molecular BiophysicsStructural properties determining low K+ affinity of the selectivity filter in the TWIK1 K+ channel
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This work was supported in part by the Japan Society for the Promotion of Science KAKENHI Grants 25840122 and 17K15109 (to H. T.); 16H00778, 16KT0165, and 17K05757 (to M. H.); and 22247024, 22770159, 24650203, 26640047, and 26708002 (to Y. F.); NINS program for cross-disciplinary study (to Y. F. and K. N.); the Cooperative Study Program of National Institute for Physiological Sciences; and JST CREST Grant JPMJCR17N5. The authors declare that they have no conflicts of interest with the contents of this article.
This article contains Figs. S1–S7, supporting Methods, supporting Movies S1–S11, and supporting Refs. 1–2.
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Present address: Dept. of Physiology, Division of Life Sciences, Faculty of Medicine, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan.