Precise Formation of a Catalyst Having a Specified Field for Use in Extremely Difficult Substrate Conversion Reactions

• Project Area: Precise Formation of a Catalyst Having a Specified Field for Use in Extremely Difficult Substrate Conversion Reactions
• Project/Area Number: 15K21707
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Multi-year Fund
• Review Section: Science and Engineering
• Research Institution: Osaka University
• Principal Investigator: Mashima Kazushi 大阪大学, 基礎工学研究科, 教授 (70159143)
• Co-Investigator(Kenkyū-buntansha): 野崎 京子 東京大学, 大学院工学系研究科(工学部), 教授 (60222197) ; 岩澤 伸治 東京工業大学, 理学院, 教授 (40168563) ; 林 高史 大阪大学, 工学研究科, 教授 (20222226)
• Project Period (FY): 2015-11-06 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥82,420,000 (Direct Cost: ¥63,400,000、Indirect Cost: ¥19,020,000); Fiscal Year 2019: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000); Fiscal Year 2018: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000); Fiscal Year 2017: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000); Fiscal Year 2016: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000); Fiscal Year 2015: ¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
• Keywords: 精密制御反応場 / 触媒反応 / 高難度物質変換 / 国際共同研究 / 国際シンポジウム / 海外講演支援 / 白金錯体触媒 / C-H結合活性化 / カルボキシル化反応 / ボロン酸反応場 / 選択的アシル化 / 二酸化炭素固定化

Outline of Final Research Achievements

Our international activity supporting group promoted international joint research, invitation of overseas researchers, hiring foreign post-doctoral researchers to continuously conduct multiple international joint research with the aid of International Advisory Board of this program, resulted in publishing many international co-authored papers. In addition, through joint research with foreign post-doctoral researchers, it has made a significant contribution to the development of English skill (discussions and presentations in English) for PhD course students.

Academic Significance and Societal Importance of the Research Achievements

国外の第一線で活躍する研究者との交流および国際共同研究を強力に推進することにより、本学術領域研究の目的である学際的融合を誘起し「精密制御反応場」の創出に大きく寄与する結果となった。これらの活動を通じて、我が国の触媒開発力を含めた有機合成化学の国際的なリーダーシップの獲得に繋がるとともに、国際的な舞台で活躍する若手研究者の育成にもつながったという観点で意義深いものである。

Research Products

• [Int'l Joint Research] ETH Zurich(スイス)
• [Int'l Joint Research] UC Berkeley/University of Minnesota(米国)
• [Int'l Joint Research] RWTH Aachen/University of Tubingen(ドイツ)
• [Int'l Joint Research] Stockholm University(スウェーデン)
• [Int'l Joint Research] ETH Zurich(スイス)
• [Int'l Joint Research] ICIQ(Spain)
• [Int'l Joint Research] ETH Zurich(Switzerland)
• [Journal Article] Hydrodehalogenation of alkyl halides catalyzed by a trichloroniobium complex with a redox active α-diimine ligand (2019)
  • Author(s): Nishiyama Haruka、Hosoya Hiromu、Parker Bernard F.、Arnold John、Tsurugi Hayato、Mashima Kazushi
  • Journal Title: Chemical Communications Volume: 55 Issue: 50 Pages: 7247-7250
  • DOI: 10.1039/c9cc03268a
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Asymmetric Hydrogenation of Aryl Perfluoroalkyl Ketones Catalyzed by Rhodium(III) Monohydride Complexes Bearing Josiphos Ligands (2019)
  • Author(s): Bruning Fabian、Nagae Haruki、Kach Daniel、Mashima Kazushi、Togni Antonio
  • Journal Title: Chemistry ? A European Journal Volume: 25 Issue: 46 Pages: 10818-10822
  • DOI: 10.1002/chem.201902585
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] α-Diimine-Niobium Complex-Catalyzed Deoxychlorination of Benzyl Ethers with Silicon Tetrachloride (2019)
  • Author(s): Parker Bernard F.、Hosoya Hiromu、Arnold John、Tsurugi Hayato、Mashima Kazushi
  • Journal Title: Inorganic Chemistry Volume: 58 Issue: 19 Pages: 12825-12831
  • DOI: 10.1021/acs.inorgchem.9b01784
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Synthesis of Pyridylimido Complexes of Tantalum and Niobium by Reductive Cleavage of the N?N Bond of 2,2′-Azopyridine: Precursors for Early?Late Heterobimetallic Complexes (2019)
  • Author(s): Kawakita Kento、Kakiuchi Yuya、Beaumier Evan P.、Tonks Ian A.、Tsurugi Hayato、Mashima Kazushi
  • Journal Title: Inorganic Chemistry Volume: 58 Issue: 22 Pages: 15155-15165
  • DOI: 10.1021/acs.inorgchem.9b02043
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Bis(imido)vanadium(V)-Catalyzed [2+2+1] Coupling of Alkynes and Azobenzenes Giving Multisubstituted Pyrroles (2019)
  • Author(s): Kento Kawakita, Evan P. Beaumier, Yuya Kakiuchi, Hayato Tsurugi, Ian A. Tonks, Kazushi Mashima
  • Journal Title: Journal of the American Chemical Society Volume: 141 Issue: 10 Pages: 4194-4198
  • DOI: 10.1021/jacs.8b13390
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Activation of O2 by Organosilicon Reagents Yields Quantitative Amounts of H2O2 or (Me3Si)2O2 for Efficient O‐Transfer Reactions (2018)
  • Author(s): Keishi Yamamoto, Shinji Tanaka, Hiromu Hosoya, Hayato Tsurugi, Kazushi Mashima, Christophe Coperet
  • Journal Title: Helvetica Chimica Acta Volume: 101 Issue: 12
  • DOI: 10.1002/hlca.201800156
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Silica-Supported Isolated Molybdenum Di-oxo Species: Formation and Activation with Organosilicon Agent for Olefin Metathesis (2018)
  • Author(s): Keishi Yamamoto, Ka Wing Chan, Victor Mougel, Haruki Nagae, Hayato Tsurugi, Olga V. Safonova, Kazushi Mashima, and Christophe Coperet
  • Journal Title: Chem. Commun. Volume: 54 Issue: 32 Pages: 3989-3992
  • DOI: 10.1039/c8cc01876f
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Dehydrogenation of Dimethylamine?Borane Catalyzed by Half-Sandwich Ir and Rh Complexes: Mechanism and the Role of Cp* Noninnocence (2018)
  • Author(s): Pal Shrinwantu、Kusumoto Shuhei、Nozaki Kyoko
  • Journal Title: Organometallics Volume: 37 Issue: 6 Pages: 906-914
  • DOI: 10.1021/acs.organomet.7b00889
  • Peer Reviewed
• [Journal Article] Facile Styrene Formation from Ethylene and a Phenylplatinum(II) Complex Leading to an Observable Platinum(II) Hydride (2017)
  • Author(s): Pal Shrinwantu、Kusumoto Shuhei、Nozaki Kyoko
  • Journal Title: Organometallics Volume: 36 Issue: 3 Pages: 502-505
  • DOI: 10.1021/acs.organomet.6b00892
  • Peer Reviewed
• [Journal Article] Low Temperature Activation of Supported Metathesis Catalysts by Organosilicon Reducing Agents (2016)
  • Author(s): Victor Mougel, Ka-Wing Chan, Georges Siddiqi, Kento Kawakita, Haruki Nagae, Hayato Tsurugi, Kazushi Mashima, Olga Safonova, Christophe Coperet
  • Journal Title: ACS Central Science Volume: 2 Issue: 8 Pages: 569-576
  • DOI: 10.1021/acscentsci.6b00176
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Presentation] 2,2’-アゾピリジンの窒素－窒素二重結合の還元的切断を経たタンタル及びニオブのピリジルイミド錯体の合成とロジウム錯体との複核錯体形成 (2020)
  • Author(s): Yuya Kakiuchi, Kento Kawakita, Evan Beaumier, Takuya Akiyama, Ian Tonks, Hayato Tsurugi, Kazushi Mashima
  • Organizer: 日本化学会第100春季年会
• [Presentation] Bis(imido)vanadium-catalyzed [2+2+1]-Coupling of Alkynes and Azobenzene for Environmentally Benign Synthesis of Multi-Substituted Pyrroles (2019)
  • Author(s): Hayato Tsurugi, Kento Kawakita, Yuya Kakiuchi, Evan Beamuier, Ian A. Tonks, Kazushi Mashima
  • Organizer: OMCOS-2019
  • Int'l Joint Research
• [Presentation] Bis(imido)vanadium(V)-catalyzed Multi-substituted Pyrrole Synthesis From Alkynes and Azobenzene via N=N Double Bond Cleavage (2019)
  • Author(s): Yuya Kakiuchi, Kento Kawakita, Evan Beaumier, Hayato Tsurugi, Ian Tonks, Kazushi Mashima
  • Organizer: 第66回有機金属化学討論会
• [Presentation] [2+2+1] Pyrrole Synthesis from Alkynes and Azobenzene via N=N Bond Cleavage Catalyzed by Vanadium Complexes (2019)
  • Author(s): Yuya Kakiuchi, Kento Kawakita, Evan Beaumier, Hayato Tsurugi, Ian Tonks, Kazushi Mashima
  • Organizer: 27th International Society of Heterocyclic Chemistry Congress
  • Int'l Joint Research
• [Presentation] Dehydrogenation of dimethylamine-borane catalyzed by half-sandwich Ir and Rh complexes: Mechanism and the role of Cp* non-innocence (2018)
  • Author(s): Shrinwantu Pal・楠本 周平・野崎 京子
  • Organizer: 日本化学会第98春季年会
• [Presentation] Preparation and Characterization of Highly Active Olefin Metathesis Catalyst Using Well-defined Tungsten Oxo Surface Species with Organosilicon Reductants (2017)
  • Author(s): Haruki Nagae, Victor Mougel, Ka-Wing Chan, Georges Siddiqi, Kento Kawakita, Hayato Tsurugi, Olga Safonova, Christophe Coperet, Kazushi Mashima
  • Organizer: 日本化学会第97春季年会
  • Place of Presentation: 慶応義塾大学、神奈川県横浜市
  • Year and Date: 2017-03-16
• [Presentation] パラジウム及び光酸化還元触媒を用いるハロゲン化アリールの可視光駆動型カルボキシル化反応 (2017)
  • Author(s): 下牧 克也・村田 慧・マーティン ルーベン・ 岩澤 伸治
  • Organizer: 第６４回有機金属化学討論会
• [Presentation] Reaction of Olefins with Phenylplatinum Complexes Supported by Mixed Donor Ligands (2017)
  • Author(s): Shrinwantu Pal・楠本 周平・野崎 京子
  • Organizer: 日本化学会第97春季年会
• [Remarks] 新学術領域研究 精密制御反応場
  • URL: http://precisely-designed-catalyst.jp/
• [Remarks] 精密制御反応場ＨＰ
  • URL: http://precisely-designed-catalyst.jp/index.html
• [Remarks] 精密制御反応場HP
  • URL: http://precisely-designed-catalyst.jp/
• [Remarks] 精密制御反応場HP
  • URL: http://precisely-designed-catalyst.jp/index-e.html