| Project Area | Chromosome Orchestration System |
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| Project/Area Number |
15K21761
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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| Allocation Type | Multi-year Fund |
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| Review Section |
Biological Sciences
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
岩崎 博史 東京工業大学, 科学技術創成研究院, 教授 (60232659)
篠原 彰 大阪大学, 蛋白質研究所, 教授 (00252578)
深川 竜郎 大阪大学, 生命機能研究科, 教授 (60321600)
広田 亨 公益財団法人がん研究会, がん研究所 実験病理部, 部長 (50421368)
平野 達也 国立研究開発法人理化学研究所, 開拓研究本部, 主任研究員 (50212171)
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| Project Period (FY) |
2015-11-06 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥79,820,000 (Direct Cost: ¥61,400,000、Indirect Cost: ¥18,420,000)
Fiscal Year 2019: ¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2018: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
Fiscal Year 2017: ¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2016: ¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2015: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
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| Keywords | 染色体動態 / 染色体機能 / 細胞周期 / 数理モデル / 染色体構築 / 癌 / 老化 / 染色体構造 / 転写 / 組換え / 複製 / 染色体ダイナミクス / ３次元構造 / ４次元構造 / 3次元構造 / 4次元構造 |
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| Outline of Final Research Achievements |
International group meetings were held every other year with the participation of foreign advisors (evaluator; Dr. John Difley, Frank Uhlmann, Susan Gasser, Camilla Sjogren). Through international joint research, including the overseas exchange of researchers from CNRS (France), Karolinska Research Institute (Sweden), Philadelphia Children's Hospital (USA), Crick Institute (UK), Oxford University (UK), IMP (Austria), CIB (Spain), FMI (Switzerland), etc., publication of 53 internationally co-authored papers were supported. Several conferences were held jointly with EMBO and GRC to enhance the presence of Japan in the field of chromosome research. These joint conferences offered the opportunities to exchange information and to broaden the experience of young promising Japanese researchers.
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| Academic Significance and Societal Importance of the Research Achievements |
国際共同研究、国際班会議、国際シンポジウム、EMBO WorkshopやGRC(Gordon Reserch Conference)の共催、国際共著論文（53編）の発表を通じ、染色体分野での我が国のプレゼンスを示すとともに、海外での研究交流の機会を数多く提供した。特に、外国人アドバイザーの存在は領域研究が海外に開かれ、さらに若手研究者が海外に目を向ける機会ともなり、日本の将来を担う研究者の育成に貢献できた。
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