宇宙からひも解く新たな生命制御機構の統合的理解

• Project Area: "LIVING IN SPACE" - Integral Understanding of life-regulation mechanism from "SPACE"
• Project/Area Number: 15H05935
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Complex systems
• Research Institution: Japan Aerospace EXploration Agency
• Principal Investigator: 古川 聡 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 上席研究開発員 (20726260)
• Co-Investigator(Kenkyū-buntansha): 根井 充 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 人材育成センター, センター長(定常) (10164659) ; 松崎 一葉 筑波大学, 医学医療系, 教授 (10229453) ; 日出間 純 東北大学, 生命科学研究科, 准教授 (20250855) ; 東端 晃 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主任研究開発員 (30360720) ; 東谷 篤志 東北大学, 生命科学研究科, 教授 (40212162) ; 成瀬 恵治 岡山大学, 医歯薬学総合研究科, 教授 (40252233) ; 瀬原 淳子 京都大学, ウイルス・再生医科学研究所, 教授 (60209038) ; 高橋 昭久 群馬大学, 重粒子線医学推進機構, 教授 (60275336) ; 井上 夏彦 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主任研究開発員 (60277811) ; 長瀬 博 筑波大学, 国際統合睡眠医科学研究機構, 教授 (70383651) ; 森田 啓之 岐阜大学, 大学院医学系研究科, 教授 (80145044) ; 岩崎 賢一 日本大学, 医学部, 教授 (80287630) ; 那須 正夫 大阪大谷大学, 薬学部, 客員教授 (90218040) ; 村井 正 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 参事 (10748958) ; 嶋津 徹 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主幹研究開発員 (20639158) ; 村上 敬司 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主幹研究開発員 (40421870)
• Project Period (FY): 2015-06-29 – 2020-03-31
• Project Status: Granted (Fiscal Year 2019)
• Budget Amount: ¥72,410,000 (Direct Cost: ¥55,700,000、Indirect Cost: ¥16,710,000); Fiscal Year 2019: ¥14,820,000 (Direct Cost: ¥11,400,000、Indirect Cost: ¥3,420,000); Fiscal Year 2018: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000); Fiscal Year 2017: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000); Fiscal Year 2016: ¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000); Fiscal Year 2015: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
• Keywords: 特殊環境 / 社会医学 / ストレス / 微小重力 / 放射線 / 宇宙 / 無重力 / 微生物

Outline of Annual Research Achievements

長期宇宙滞在時、無重力の物理ストレスは筋萎縮や骨密度低下を、閉鎖環境の精神的ストレスは体内リズム不調を、放射線被ばく等の環境リスクはDNA 変異等をきたす。有人宇宙探査での超長期宇宙滞在に挑戦する時代にあって、これらは今解決すべき課題である。同時にこれら課題への深い理解は、地上の高齢化・ストレス社会における生命維持・恒常性の担保に貢献し、健康長寿社会につながる。
本領域では[A01～03]に横断・補完的研究[B01]を加えた11の計画研究と30の公募研究の相乗的展開により、上記目的達成を目指している。H30年度は新たに78本の論文が発行された。
これまで[A01]宇宙からひも解かれる生命分子基盤の理解では、細胞の重力応答をリアルタイム観察できる遠心蛍光顕微鏡システム開発(成瀬)、微小重力下で線虫TGF-β/DBL-1の発現低下(東谷)、神経筋接合部の維持因子活性化の検出プローブを開発(瀬原)、骨代謝における重力応答機構の発見(茶谷)、視床下部摂食中枢活動のライブイメージ化(川上)等、[A02]生命体個体の高次恒常性・適応機構と生命医学への展開では、重力負荷による脳血流量の低下(岩崎)、宇宙飛行で前庭系を介した血圧調節機能低下(森田)、オレキシン1型受容体特異的拮抗薬リード化合物の発見、睡眠を制御する2遺伝子を世界に先駆け発見(長瀬)、閉鎖環境によるストレスマーカー候補の検出(古川)、宇宙長期飼育マウスの破骨細胞による骨破壊が亢進(篠原)等、[A03]宇宙環境によるリスク因子研究では、模擬無重力装置に放射線同期照射システムを構築 (高橋)、国際宇宙ステーションでの微生物モニタリング(那須)等、[B01]では、クマムシの放射線耐性メカニズム解明(國枝)、放射線被ばくによる細胞ダメージの可視化(沢野)等があり、宇宙滞在はじめ極限的環境での生体維持機構やその基盤的研究が進んでいる。

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

各班とも、ほぼ予定通り研究が進捗している。また、例えば以下のような、単独の研究チームではできないようなサイエンスを行うクリエイティブは研究領域ができてきている。
・A01-1班開発の、3Dクリノスタットや遠心装置に搭載可能な高性能・コンパクトな蛍光顕微鏡システム、あるいはA03-2班開発の放射線照射用クリノスタットを使用した上に、バイオイメージングも導入し、模擬微小重力と放射線両者の相互作用を調べる。
・横断的なオミックス解析
さらに、外国への研究者派遣や、外国からの研究者招聘により、国際共同研究が始まっている。かつ、若手研究者合宿実施は、若手研究者交流促進や人材育成に貢献している。
以上の理由により、現状おおむね順調に進展していると考える。

Strategy for Future Research Activity

[A01][A02][A03]という研究の縦串に加え、横串として、H28年度から公募班として領域課題の横断・補完的研究[B01]が加わった。H30年度から新たな公募班30班が参画して本領域は41班となり、さらに「睡眠―リズム」、「メンタルストレス」、「脳―循環系」、「骨―運動」、「免疫系―微生物」、「生命維持―物質生産」、「重力―メカノ応答」、「代謝変化」、「筋―萎縮」、「宇宙放射線―損傷」という横串の階層を導入することで各研究を有機的にオーバーラップさせ、総花的になることなく、実質的な連携・共同研究ができる組織とし、研究を推進する。

Research Products

• [Int'l Joint Research] バージニア大学/コロラド州立大学/Prairie View A&M University(米国)
• [Int'l Joint Research] ドイツ航空宇宙センター(ドイツ)
• [Int'l Joint Research] パスツール研究所(フランス)
• [Int'l Joint Research] バルセロナ大学/Pompeu Fabra University(スペイン)
• [Int'l Joint Research] ベルゲン大学(ノルウェー)
• [Int'l Joint Research]
• [Int'l Joint Research] スタンフォード大学/ハーバード大学/バージニア大学(アメリカ合衆国)
• [Int'l Joint Research] ドイツ航空宇宙センター/マールブルグ大学/Institute of Aerospace Medicine(ドイツ)
• [Int'l Joint Research] パスツール研究所(フランス)
• [Int'l Joint Research] Institute of Science and Technology(オーストリア)
• [Int'l Joint Research] スウェーデン農業科学大学(スウェーデン)
• [Int'l Joint Research] スタンフォード大学/フロリダ州立大学/バージニア大学(アメリカ合衆国)
• [Int'l Joint Research] German Aerospace Center/マールブルグ大学/Institute of Aerospace Medicine(ドイツ)
• [Int'l Joint Research] パスツール研究所(フランス)
• [Int'l Joint Research] Institute of Science and Technology(オーストリア)
• [Journal Article] Development of a simple thermal method for measuring sap flow in plants for space experiments (2019)
  • Author(s): A. Tokuda, Y. Kitaya, H. Hirai,
  • Journal Title: Biol. Sci. Space Volume: Vol.32 Issue: 0 Pages: 17-21
  • DOI: 10.2187/bss.32.17
  • NAID: 130007543443
  • Year and Date: 2019-01-08
  • Peer Reviewed
• [Journal Article] Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/reperfusion injury in the kidney (2019)
  • Author(s): Inoue T,Abe C, Kohro T, Tanaka S, Huang L, Yao J, Zheng S, Ye H, Inagi R, Stornetta RL, Rosin DL, Nangaku M, Wada Y, Okusa MD
  • Journal Title: Kidney International Volume: 95(3) Pages: 563-576
  • DOI: 10.1016/j.kint.2018.09.020
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Increased Hematopoietic Stem Cells Measured as Endogenous Spleen Colonies in Radiation-Induced Adaptive Response in Mice (Yonezawa Effect) (2019)
  • Author(s): Cuihua Liu, Hirokazu Hirakawa, Kaoru Tanaka, Fazliana Mohd Saaya, Mitsuru Nenoi, Akira Fujimori, Bing Wang
  • Journal Title: Dose-Response Volume: - Pages: 1-10
  • DOI: 10.1177/1559325818790152
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A Small Fish Model for Quantitative Analysis of Radiation Effects Using Visualized Thymus Responses in GFP Transgenic Medaka (2019)
  • Author(s): Maruyama K., Iwanami N., Maruyama-Hayakawa T., Doi K., Wang B.
  • Journal Title: International Journal of Radiation Biology Volume: - Pages: 1-16
  • DOI: 10.1080/09553002.2019.1589019
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Radiobiological Characterization of Canine Malignant Melanoma Cell Lines with Different Types of Ionizing Radiation and Efficacy Evaluation with Cytotoxic Agents. (2019)
  • Author(s): Yoshikawa Hiroto、Sunada Shigeaki、Hirakawa Hirokazu、Fujimori Akira、Elmegerhi Suad、Leary Del、Kato Takamitsu
  • Journal Title: International Journal of Molecular Sciences Volume: 20 Pages: 1-12
  • DOI: 10.3390/ijms20040841
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Extracellular adenosine and slow-wave sleep are increased after ablation of nucleus accumbens core astrocytes and neurons in mice (2019)
  • Author(s): Zhou X, Oishi Y, Cherasse Y, Korkutata M, Fujii S, Lee CY, Lazarus M
  • Journal Title: Neurochem Int Volume: 124 Pages: 256-263
  • DOI: 10.1016/j.neuint.2019.01.020
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function (2019)
  • Author(s): Korkutata M, Saitoh T, Cherasse Y, Ioka S, Duo F, Qin R, Murakoshi N, Fujii S, Zhou X, Sugiyama F, Chen JF, Kumagai H, Nagase H, Lazarus M
  • Journal Title: Neuropharmacology Volume: 144 Pages: 122-132
  • DOI: 10.1016/j.neuropharm.2018.10.022
  • NAID: 120006583051
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Aqueous/Aqueous Micro Phase Separation: Construction of an Artificial Model of Cellular Assembly (2019)
  • Author(s): Sakuta Hiroki、Fujimoto Tadashi、Yamana Yusuke、Hoda Yusuke、Tsumoto Kanta、Yoshikawa Kenichi
  • Journal Title: Frontiers in Chemistry Volume: 7 Pages: 44-44
  • DOI: 10.3389/fchem.2019.00044
  • Peer Reviewed / Open Access
• [Journal Article] Circumnutational movement in rice coleoptiles involves the gravitropic response: analysis of an agravitropic mutant and space-grown seedlings (2019)
  • Author(s): Kobayashi Akie、Kim Hye-Jeong、Tomita Yuta、Miyazawa Yutaka、Fujii Nobuharu、Yano Sachiko、Yamazaki Chiaki、Kamada Motoshi、Kasahara Haruo、Miyabayashi Sachiko、Shimazu Toru、Fusejima Yasuo、Takahashi Hideyuki
  • Journal Title: Physiologia Plantarum Volume: 165 Pages: 464-475
  • DOI: 10.1111/ppl.12824
  • Peer Reviewed
• [Journal Article] FRET-based tension measurement across actin-associated mechanotransductive structures using Lima1. (2019)
  • Author(s): Hirano S, Yamamoto T, Michiue T
  • Journal Title: Int. J. Dev. Biol. Volume: 62 Pages: 631-636
  • DOI: 10.1387/ijdb.180110tm
  • Peer Reviewed
• [Journal Article] Progression of peripheral vestibular dysfunctions in patients with a mitochondrial A3243G mutation. (2019)
  • Author(s): Inoue Aki、Iwasaki Shinichi、Fujimoto Chisato、Kinoshita Makoto、Yamasoba Tatsuya
  • Journal Title: Otol Neurotol Volume: 40 Pages: 359-364
  • DOI: 10.1097/mao.0000000000002091
  • Peer Reviewed / Open Access
• [Journal Article] Plasminogen activator inhibitor‐1 deficiency suppresses osteoblastic differentiation of mesenchymal stem cells in mice (2019)
  • Author(s): Takafuji Y, Tatsumi K, Ishida M, Kawao N, Okada K, Matsuo O, Kaji H.
  • Journal Title: Journal of Cellular Physiology Volume: 234 Pages: 9687-9697
  • DOI: 10.1002/jcp.27655
  • Peer Reviewed
• [Journal Article] Increased chromosome aberrations in cells exposed simultaneously to simulated microgravity and radiation. (2019)
  • Author(s): Hada M, Ikeda H, Rhone JR, Beitman AJ, Plante I, Souda H, Yoshida Y, Held KD, Fujiwara K, Saganti PB, Takahashi A.
  • Journal Title: Int J Mol Sci Volume: 20 Pages: 43-43
  • DOI: 10.3390/ijms20010043
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Nucleolar protein nucleolin functions in replication stress-induced DNA damage responses. (2019)
  • Author(s): Kawamura K, Qi F, Meng Q, Hayashi I, Kobayashi J.
  • Journal Title: J Radiat Res. Volume: -
  • DOI: 10.1093/jrr/rry114
  • NAID: 120006647310
  • Peer Reviewed / Open Access
• [Journal Article] G9a-dependent histone methylation can be induced in G1 phase of cell cycle. (2019)
  • Author(s): Fukuda M, Sakaue-Sawano A, Shimura C, Tachibana M, Miyawaki A, Shinkai Y.
  • Journal Title: Sci. Rep. Volume: 9 Pages: 956-956
  • DOI: 10.1038/s41598-018-37507-5
  • Peer Reviewed / Open Access
• [Journal Article] Quantitative phosphoproteomic analysis of the molecular substrates of sleep need. (2018)
  • Author(s): Z. Wang, J. Ma, C. Miyoshi, Y. Li, M Sato, Y. Ogawa, T. Lou, C. Ma, X. Gao, C. Lee, T. Fujiyama, X. Yang, S. Zhou, N. Hotta-Hirashima, D. Klewe-Nebenus, A. Ikkyu, M. Kakizaki, S. Kanno, L. Cao, S. Takahashi, J. Peng, Y. Yu, H. Funato, M. Yanagisawa, Q. Liu
  • Journal Title: Nature Volume: 558 Pages: 435-439
  • DOI: 10.1038/s41586-018-0218-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Combating herpesvirus encephalitis by potentiating a TLR3?mTORC2 axis (2018)
  • Author(s): Sato R, Kato A, Chimura T, Saitoh SI, Shibata T, Murakami Y, Fukui R, Liu K, Zhang Y, Arii J, Sun-Wada GH, Wada Y, Ikenoue T, Barber GN, Manabe T, Kawaguchi Y, Miyake K.
  • Journal Title: Nature immunology. Volume: 19 Pages: 1071-1082
  • DOI: 10.1038/s41590-018-0203-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression (2018)
  • Author(s): Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M
  • Journal Title: Nature Communications Volume: 9 Pages: 4832-4832
  • DOI: 10.1038/s41467-018-07305-8
  • NAID: 120006583017
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice. (2018)
  • Author(s): Ford MJ, Yeyati PL, Mali GR, Keighren MA, Waddell SH, Mjoseng HK, Douglas AT, Hall EA, Sakaue-Sawano A, Miyawaki A, Meehan RR, Boulter L, Jackson IJ, Mill P, Mort RL.
  • Journal Title: Dev Cell Volume: 47 Pages: 509-523
  • DOI: 10.1016/j.devcel.2018.10.027
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The choroid plexus is an important circadian clock component. (2018)
  • Author(s): Myung Jihwan、Schmal Christoph、Hong Sungho、Tsukizawa Yoshiaki、Rose Pia、Zhang Yong、Holtzman Michael J.、De Schutter Erik、Herzel Hanspeter、Bordyugov Grigory、Takumi Toru
  • Journal Title: Nat Commun Volume: 9 Pages: 1062-1062
  • DOI: 10.1038/s41467-018-03507-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis (2018)
  • Author(s): Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E.
  • Journal Title: Development. Volume: 145 Pages: 164004-164004
  • DOI: 10.1242/dev.164004
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Reactive oxygen species up-regulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells. (2018)
  • Author(s): Uchida, T., Sakashita, Y., Kitahata, K., Yamashita, Y., Tomida, C., Kimori, Y., Komatsu, A., Hirasaka, K., Ohno, A., Nakao, R., Higashitani, A., Higashibata, A., Ishioka, N., Shimazu, T., Kobayashi, T., Okumura, Y., Choi, I., Oarada, M., Mills, E. M., Teshima-Kondo, S., Takeda, S., Tanaka, E., Tanaka, K., Sokabe, M., and Nikawa, T.
  • Journal Title: Am J Physiol: Cell Physiol Volume: 印刷中
  • DOI: 10.1152/ajpcell.00184.2017
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] TRPC5-eNOS axis negatively regulates ATP-induced cardiomyocyte hypertrophy (2018)
  • Author(s): Sunggip C, Shimoda K, Oda S, Tanaka T, Nishiyama K, Mangmool S, Nishimura A, Numaga-Tomita T and Nishida M
  • Journal Title: Frontiers in pharmacology Volume: 9 Pages: 1-10
  • DOI: 10.3389/fphar.2018.00523
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish (2018)
  • Author(s): Lal P, Tanabe H, Suster ML, Ailani D, Kotani Y, Muto A, Itoh M, Iwasaki M, Wada H, Yaksi E, Kawakami K.
  • Journal Title: BMC Biology Volume: 16 Pages: 45-45
  • DOI: 10.1186/s12915-018-0502-y
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of C1 neurons in anti-inflammatory reflex: Mediation between afferents and efferents. (2018)
  • Author(s): Chikara Abe, Tsuyoshi Inoue
  • Journal Title: Neuroscience Research Volume: 136 Pages: 6-12
  • DOI: 10.1016/j.neures.2018.05.001
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Manganese in toenails is associated with hearing loss at high frequencies in humans (2018)
  • Author(s): Ohgami N, Li X, Yajima I, Oshino R, Ohgami K, Kato Y, Ahsan N, Akhand AA, Kato M
  • Journal Title: Biomarkers Volume: 23 Pages: 533-539
  • DOI: 10.1080/1354750x.2018.1458153
  • NAID: 120006536930
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Arsenic level in toenails is associated with hearing loss in humans (2018)
  • Author(s): Li X, Ohgami N, Yajima I, Xu H, Iiida M, Ohino R, Ninomiya H, Shen D, Ahsan N, Akhand AA, Kato M
  • Journal Title: PLOS ONE Volume: 13
  • DOI: 10.1371/journal.pone.0198743
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise (2018)
  • Author(s): Ninomiya H, Ohgami N, Oshino R, Kato M, Ohgami K, Li X, Shen D, Iida M, Yajima I, Angelidis CE, Adachi H, Katsuno M, Sobue G, Kato M.
  • Journal Title: Hearing Res Volume: - Pages: 49-54
  • DOI: 10.1016/j.heares.2018.02.006
  • NAID: 120006517664
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Palmitoyl ascorbic acid 2-glucoside has the potential to protect mammalian cells from high-LET carbon-ion radiation (2018)
  • Author(s): Alexis H. Haskins, Dylan J. Buglewicz, Hirakawa Hirokazu, Akira Fujimori, Yasushi Aizawa, Takamitsu A. Kato
  • Journal Title: Scientific Reports Volume: 8(1) Pages: 1-7
  • DOI: 10.1038/s41598-018-31747-1
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] DNA Repair Deficient Chinese Hamster Ovary Cells Exhibiting Differential Sensitivity to Charged Particle Radiation under Aerobic and Hypoxic Conditions (2018)
  • Author(s): Cartwright Ian M.、Su Cathy、Haskins Jeremy S.、Salinas Victoria A.、Sunada Shigeaki、Yu Hao、Uesaka Mitsuru、Hirakawa Hirokazu、Chen David J.、Fujimori Akira、Kato Takamitsu A.
  • Journal Title: International Journal of Molecular Sciences Volume: 19 Pages: 1-12
  • DOI: 10.3390/ijms19082228
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Apoptosis Induction by Iron Radiation via Inhibition of Autophagy in Trp53+/- Mouse Testes: Is Chronic Restraint-Induced Stress a Modifying Factor? (2018)
  • Author(s): Hongyan Li, Bing Wang, Hong Zhang, Takanori Katsube, Yi Xie, Lu Gan.
  • Journal Title: International Journal of Biological Sciences Volume: 14(9) Pages: 1109-1121
  • DOI: 10.7150/ijbs.22805
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Sleep and Wakefulness Are Controlled by Ventral Medial Midbrain/Pons GABAergic Neurons in Mice (2018)
  • Author(s): Takata Y, Oishi Y, Zhou XZ, Hasegawa E, Takahashi K, Cherasse Y, Sakurai T, Lazarus M
  • Journal Title: J Neurosci Volume: 0598-18 Pages: 10080-10092
  • DOI: 10.1523/jneurosci.0598-18.2018
  • NAID: 120006582772
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Encoding seasonal information in a two-oscillator model of the multi-oscillator circadian clock (2018)
  • Author(s): Jihwan Myung, Scott D Pauls
  • Journal Title: European Journal of Neuroscience Volume: In press Pages: 1-10
  • DOI: 10.1111/ejn.13697
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] A tRNA-based multiplex sgRNA expression system in zebrafish and its application to generation of transgenic albino fish. (2018)
  • Author(s): Tomoya Shiraki, Koichi Kawakami
  • Journal Title: Scientific reports Volume: 8 Pages: 13366-13366
  • DOI: 10.1038/s41598-018-31476-5
  • Peer Reviewed / Open Access
• [Journal Article] Integrin β1 activity is required for cardiovascular formation in zebrafish (2018)
  • Author(s): Iida A, Wang Z, Hirata H, Sehara-Fujisawa A
  • Journal Title: Genes to Cells Volume: 23 Pages: 938-951
  • DOI: 10.1111/gtc.12641
  • Peer Reviewed
• [Journal Article] Nematode Muscles Project in Spaceflight Experiment (2018)
  • Author(s): Surabhi Sudevan, Toko Hashizume, Sachiko Yano, Kana Kuriyama, Kenta Momma, Shunsuke Harada, Masumi Umehara, Akira Higashibata, Atsushi Higashitani
  • Journal Title: Biol. Sci. Space Volume: 768:00:00 Issue: 0 Pages: 6-10
  • DOI: 10.2187/bss.32.6
  • NAID: 130007430368
  • Peer Reviewed / Open Access
• [Journal Article] Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis (2018)
  • Author(s): Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Manabe T, Ishigaki Y, Ohno M, Hinoi E.
  • Journal Title: Stem Cell Reports. Volume: 11 Pages: 228-241
  • DOI: 10.1016/j.stemcr.2018.05.020
  • Peer Reviewed / Open Access
• [Journal Article] Specific Spatial Localization of Actin and DNA in a?Water/WaterMicrodroplet: Self‐Emergence of a Cell‐Like Structure (2018)
  • Author(s): Nakatani Naoki、Sakuta Hiroki、Hayashi Masahito、Tanaka Shunsuke、Takiguchi Kingo、Tsumoto Kanta、Yoshikawa Kenichi
  • Journal Title: ChemBioChem Volume: 19 Pages: 1370-1374
  • DOI: 10.1002/cbic.201800066
  • Peer Reviewed / Open Access
• [Journal Article] Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus. (2018)
  • Author(s): Kazuhide Asakawa, Koichi Kawakami
  • Journal Title: Cell Reports Volume: 576:00:00 Pages: 1562-1572
  • DOI: 10.1016/j.celrep.2018.07.024
  • Peer Reviewed / Open Access
• [Journal Article] Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire). (2018)
  • Author(s): Horie K, Kudo T, Yoshinaga R, Akiyama N, Sasanuma H, Kobayashi TJ, Shimbo M, Jeon H, Miyao T, Miyauchi M, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T.
  • Journal Title: Biochem Biophys Res Commun. Volume: 501 Pages: 754-750
  • Peer Reviewed
• [Journal Article] Anti-mouse RANKL Antibodies Inhibit Alveolar Bone Destruction in Periodontitis Model Mice (2018)
  • Author(s): Kuritani M, Sakai N, Karakawa A, Isawa M, Chatani M, Negishi-Koga T, Funatsu T, Takami M.
  • Journal Title: Biol. Pharm. Bull. Volume: 41 Issue: 4 Pages: 637-643
  • DOI: 10.1248/bpb.b18-00026
  • NAID: 130006602562
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Aging is a risk factor for utricular dysfunction in idiopathic benign paroxysmal positional vertigo. (2018)
  • Author(s): Fujimoto Chisato、Kawahara Takuya、Kinoshita Makoto、Kikkawa Yayoi S.、Sugasawa Keiko、Yagi Masato、Yamasoba Tatsuya、Iwasaki Shinichi、Murofushi Toshihisa
  • Journal Title: Front Neurol Volume: 9 Pages: 1049-1049
  • DOI: 10.3389/fneur.2018.01049
  • Peer Reviewed / Open Access
• [Journal Article] Dynamic cerebral autoregulation after confinement in an isolated environment for 14?days (2018)
  • Author(s): Tomokazu Kato, Ryo Yanagida, Chiharu Takko, Takuya Kurazumi, Natsuhiko Inoue, Go Suzuki, Yojiro Ogawa, Satoshi Furukawa, Ken-ichi Iwasaki
  • Journal Title: Environmental Health and Preventive Medicine Volume: 23 Pages: 61-61
  • DOI: 10.1186/s12199-018-0751-y
  • NAID: 210000130314
  • Peer Reviewed / Open Access
• [Journal Article] Improvement of balance in young adults by a sound component at 100 Hz in music. (2018)
  • Author(s): Xu H, Ohgami N, He T, Hashimoto K, Tazaki, A, Ohgami K, Takeda K, Kato M
  • Journal Title: Sci Rep Volume: 8(1) Pages: 16894-16894
  • DOI: 10.1038/s41598-018-35244-3
  • Peer Reviewed / Open Access
• [Journal Article] Noisy galvanic vestibular stimulation sustainably improves posture in bilateral vestibulopathy (2018)
  • Author(s): Fujimoto Chisato、Egami Naoya、Kawahara Takuya、Uemura Yukari、Yamamoto Yoshiharu、Yamasoba Tatsuya、Iwasaki Shinichi
  • Journal Title: Front Neurol Volume: 9 Pages: 1-9
  • DOI: 10.3389/fneur.2018.00900
  • Peer Reviewed / Open Access
• [Journal Article] A disadvantageous effect of adsorption of barium by melanin on transforming activity. (2018)
  • Author(s): Omata Y, Yoshinaga M, Yajima I, Ohgami N, Hashimoto K, Higashimura K, Tazaki A, Kato M
  • Journal Title: Chemosphere Volume: 210 Pages: 384-391
  • DOI: 10.1016/j.chemosphere.2018.07.022
  • Peer Reviewed / Open Access
• [Journal Article] The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity. (2018)
  • Author(s): Srinontong Piyarat、Wu Zhiliang、Sato Katsuya、Nagaoka Hitoshi、Maekawa Yoichi
  • Journal Title: BBRC Volume: 506 Pages: 20-26
  • DOI: 10.1016/j.bbrc.2018.10.055
  • Peer Reviewed / Open Access
• [Journal Article] Amount of daily exercise is an essential stimulation to alter the epigenome of skeletal muscle in rats (2018)
  • Author(s): Ohsawa I, Konno R, Masuzawa R, and Kawano F
  • Journal Title: Journal of Applied Physiology Volume: 125 Pages: 1097-1104
  • DOI: 10.1152/japplphysiol.00074.2018
  • Peer Reviewed
• [Journal Article] Muscle type-specific RNA polymerase II recruitment during PGC-1α gene transcription after acute exercise in adult rats (2018)
  • Author(s): Masuzawa R, Konno R, Ohsawa I. Watanabe A, and Kawano F
  • Journal Title: Journal of Applied Physiology Volume: 125 Pages: 1238-1245
  • DOI: 10.1152/japplphysiol.00202.2018
  • Peer Reviewed
• [Journal Article] Serpina3n, dominantly expressed in female osteoblasts, suppresses the phenotypes of differentiated osteoblasts in mice (2018)
  • Author(s): Ishida M, Kawao N, Okada K, Tatsumi K, Sakai K, Nishio K, Kaji H.
  • Journal Title: Endocrinology. Volume: 159 Pages: 3775-3790
  • DOI: 10.1210/en.2018-00639
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The effect of mild decrement in plasma volume simulating short-duration spaceflight on intracranial pressure (2018)
  • Author(s): Takuya Kurazumi, Yojiro Ogawa, Hiroshi Morisaki, Ken-ichi Iwasaki
  • Journal Title: npj Microgravity Volume: 4
  • DOI: 10.1038/s41526-018-0053-0
  • Peer Reviewed / Open Access
• [Journal Article] Plasminogen activator inhibitor-1 is involved in interleukin-1β-induced matrix metalloproteinase expression in murine chondrocytes (2018)
  • Author(s): Moritake A, Kawao N, Okada K, Ishida M, Tatsumi K, Matsuo O, Akagi M, Kaji H.
  • Journal Title: Modern Rheumatology Volume: 28 Pages: 1-5
  • DOI: 10.1080/14397595.2018.1525018
  • Peer Reviewed / Open Access
• [Journal Article] Time-Dependent Changes in Cerebral Blood Flow and Arterial Pressure During Mild +Gz Hypergravity (2018)
  • Author(s): Toru Konishi, Takuya Kurazumi, Tomokazu Kato, Chiharu Takko, Yojiro Ogawa, Ken-ichi Iwasaki
  • Journal Title: Aerospace Medicine and Human Performance Volume: 87：5 Pages: 787-791
  • DOI: 10.3357/amhp.5106.2018
  • Peer Reviewed
• [Journal Article] Ablation of Central Serotonergic Neurons Decreased REM Sleep and Attenuated Arousal Response (2018)
  • Author(s): Iwasaki Kanako、Komiya Haruna、Kakizaki Miyo、Miyoshi Chika、Abe Manabu、Sakimura Kenji、Funato Hiromasa、Yanagisawa Masashi
  • Journal Title: Frontiers in Neuroscience Volume: 12 Pages: 1-13
  • DOI: 10.3389/fnins.2018.00535
  • Peer Reviewed / Open Access
• [Journal Article] Noisy vestibular stimulation increases gait speed in normals and in bilateral vestibulopathy. (2018)
  • Author(s): Iwasaki Shinichi、Fujimoto Chisato、Egami Naoya、Kinoshita Makoto、Togo Fumiharu、Yamamoto Yoshiharu、Yamasoba Tatsuya
  • Journal Title: Brain Stimul Volume: - Pages: 709-715
  • DOI: 10.1016/j.brs.2018.03.005
  • Peer Reviewed
• [Journal Article] Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain (2018)
  • Author(s): T Fujiyama, S Miyashita, Y Tsuneoka, K Kanemaru, M Kakizaki, S Kanno, Y Ishikawa, M Yamashita, T Owa, M Nagaoka, Y Kawaguchi, Y Yanagawa, M A. Magnuson, A Shibuya, Y Nabeshima, M Yanagisawa, H Funato*, M Hoshino*
  • Journal Title: Cell Rep Volume: 24 Pages: 79-94
  • DOI: 10.1016/j.celrep.2018.06.010
  • NAID: 120006523922
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Meal rich in rapeseed oil increases 24-h fat oxidation more than meal rich in palm oil. (2018)
  • Author(s): Katsuhiko Yajima, Kaito Iwayama, Hitomi Ogata, Insung Park, Kumpei Tokuyama
  • Journal Title: PLoS ONE Volume: 13
  • DOI: 10.1371/journal.pone.0198858
  • NAID: 120006496520
  • Peer Reviewed / Open Access
• [Journal Article] Immunolocalization of muscarinic M1 receptor in the rat medial prefrontal cortex, Journal of Comparative Neurology (2018)
  • Author(s): Oda Satoko、Tsuneoka Yousuke、Yoshida Sachine、Adachi-Akahane Satomi、Ito Masanori、Kuroda Masaru、Funato Hiromasa
  • Journal Title: J Comp Neurol. Volume: 526 Pages: 1329-1350
  • DOI: 10.1002/cne.24409
  • Peer Reviewed / Open Access
• [Journal Article] Sleep disorder risk factors among student athletes. (2018)
  • Author(s): Monma T, Ando A, Asanuma T, Yoshitake Y, Yoshida G, Miyazawa T, Ebine N, Takeda S, Omi N, Satoh M, Tokuyama K, Takeda F.
  • Journal Title: Sleep Medicine 44 Volume: 44 Pages: 76-81
  • DOI: 10.1016/j.sleep.2017.11.1130
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Synthesis of novel 1,3-dioxa-5-thiazatriquinane and 1-oxa-3,5-dithiazatriquinane derivatives and their pharmacologies (2018)
  • Author(s): Ohshita R, Kutsumura N, and Nagase H, et al
  • Journal Title: Heterocycles Volume: 97 Pages: 687-695
  • DOI: 10.3987/com-18-s(t)40
  • Peer Reviewed / Open Access
• [Journal Article] Non-invasive intracranial pressure estimation during combined exposure to CO2 and head-down tilt (2018)
  • Author(s): Kurazumi T., Ogawa Y., Yanagida R., Morisaki H., Iwasaki K.
  • Journal Title: Aerospace Medicine and Human Performance Volume: 89 Pages: 365-370
  • DOI: 10.3357/amhp.5015.2018
  • Peer Reviewed
• [Journal Article] Role of macrophages and plasminogen activator inhibitor-1 in delayed bone repair in diabetic female mice. (2018)
  • Author(s): Shimoide Takeshi、Kawao Naoyuki、Tamura Yukinori、Okada Kiyotaka、Horiuchi Yoshitaka、Okumoto Katsumi、Kurashimo Shinji、Ishida Masayoshi、Tatsumi Kohei、Matsuo Osamu、Kaji Hiroshi
  • Journal Title: Hendocrinology Volume: 159 Pages: 1875-1885
  • DOI: 10.1210/en.2018-00085
  • Peer Reviewed / Open Access
• [Journal Article] Temporary loading prevents cancer progression and immune organ atrophy induced by hind-limb unloading in mice (2018)
  • Author(s): Takahashi A, Wakihata S, Ma L, Adachi T, Hirose H, Yoshida Y, Ohira Y.
  • Journal Title: Int J Mol Sci Volume: 19 Pages: 3959-3959
  • DOI: 10.3390/ijms19123959
  • Peer Reviewed / Open Access
• [Journal Article] Albatross/FBF1 contributes to both centriole duplication and centrosome separation. (2018)
  • Author(s): Akihito Inoko, Tomoki Yano, Tatsuo Miyamoto, Shinya Matsuura, Tohru Kiyono, Naoki Goshima, Masaki Inagaki, Yuko Hayashi
  • Journal Title: Genes Cells. Volume: 23 Pages: 1023-1042
  • DOI: 10.1111/gtc.12648
  • Peer Reviewed
• [Journal Article] Selective elimination of membrane-damaged chloroplasts via microautophagy (2018)
  • Author(s): Sakuya Nakamura, Jun Hidema, Wataru Sakamoto, Hiroyuki Ishida, Masanori Izumi
  • Journal Title: Plant Physiology Volume: 177 Pages: 1007-1026
  • DOI: 10.1104/pp.18.00444
  • Peer Reviewed / Open Access
• [Journal Article] Cell behavior of the highly sticky bacterium Acinetobacter sp. Tol 5 during adhesion in laminar flows (2018)
  • Author(s): Yoshihide Furuichi, Keita Iwasaki, Katsutoshi Hori
  • Journal Title: Scientific Reports Volume: 8 Pages: 8285-8285
  • DOI: 10.1038/s41598-018-26699-5
  • Peer Reviewed / Open Access
• [Journal Article] Possibility of co-culturing Euglena gracilis and Lactuca sativa L. with biogas digestate (2018)
  • Author(s): K. Takemura, R. Endo and Y. Kitaya
  • Journal Title: Environmental Technology Volume: 39
  • DOI: 10.1080/09593330.2018.1516803
  • Peer Reviewed / Open Access
• [Journal Article] Roles of the Phosphorylation of Herpes Simplex Virus 1 UL51 at a Specific Site in Viral Replication and Pathogenicity (2018)
  • Author(s): Kato A, Oda S, Watanabe M, Oyama M, Kozuka-Hata H, Koyanagi N, Maruzuru Y, Arii J, Kawaguchi Y.
  • Journal Title: J Virol Volume: 92
  • DOI: 10.1128/jvi.01035-18
  • Peer Reviewed / Open Access
• [Journal Article] Effects of gravity on stem sap flow and water and heat exchange in the leaves of sweetpotato (2018)
  • Author(s): A. Tokuda, Y. Kitaya, H. Hirai, H. Hashimoto and Y. Inatomi
  • Journal Title: Int. J. Microgravity Sci. Appl. Volume: 35（3）
  • Peer Reviewed / Open Access
• [Journal Article] Optical clearing of the pancreas for visualization of mature β-cells and vessels in mice (2018)
  • Author(s): Nishimura W, Sakaue-Sawano A, Takahashi S, Miyawaki A, Yasuda K, Noda Y.
  • Journal Title: Islets. Volume: 10 Pages: 106-112
  • DOI: 10.1080/19382014.2018.1451282
  • Peer Reviewed
• [Journal Article] Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons. (2018)
  • Author(s): Mochizuki S, Miki H, Zhou R, Kido Y, Nishimura W, Kikuchi M, Noda Y.
  • Journal Title: Exp Cell Res Volume: 370 Pages: 601-612
  • DOI: 10.1016/j.yexcr.2018.07.025
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide profiling of histone H3K27 acetylation featured fatty acid signalling in pancreatic beta cells in diet-induced obesity in mice (2018)
  • Author(s): Nammo T, Udagawa H, Funahashi N, Kawaguchi M, Uebanso T, Hiramoto M, Nishimura W, Yasuda K.
  • Journal Title: Diabetologia Volume: 61 Pages: 2608-2620
  • DOI: 10.1007/s00125-018-4735-7
  • Peer Reviewed / Open Access
• [Journal Article] A Novel iRFP-Incorporated in vivo Murine Atherosclerosis Imaging System (2018)
  • Author(s): Kulathunga K, Hamada M, Hiraishi Y, Otake M, Tran MTN, Cheng O, Tanaka J, Sakasai T, Sakaguchi S, Sugiyama Y, Fleischmann BK, Takahashi S, Miwa Y
  • Journal Title: Scientific Reports Volume: 8 Pages: 14515-14515
  • DOI: 10.1038/s41598-018-32456-5
  • NAID: 120006542254
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog (2018)
  • Author(s): Katagiri Tomohiro、Kobayashi Minoru、Yoshimura Michio、Morinibu Akiyo、Itasaka Satoshi、Hiraoka Masahiro、Harada Hiroshi
  • Journal Title: Oncotarget Volume: 9 Pages: 10525-10535
  • DOI: 10.18632/oncotarget.24156
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Sleep/Wake Behaviors in Mice During Pregnancy and Pregnancy-Associated Hypertensive Mice (2018)
  • Author(s): Haruna Komiya, Chika Miyoshi, Kanako Iwasaki, Noriko Hotta-Hirashima, Aya Ikkyu, Satomi Kanno, Takato Honda, Masahiro Gosho, Hiromi Hamada, Toyomi Satoh, Akiyoshi Fukamizu, Hiromasa Funato, Masashi Yanagisawa
  • Journal Title: Sleep Volume: 41 Issue: 3 Pages: 1-1
  • DOI: 10.1093/sleep/zsx209
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of follistatin in muscle and bone alterations induced by gravity change in mice (2018)
  • Author(s): Kawao N, Morita H, Obata K, Tatsumi K, Kaji H.
  • Journal Title: J Cell Physiol Volume: 233 Pages: 1191-1201
  • DOI: 10.1002/jcp.25986
  • Peer Reviewed
• [Journal Article] Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge (2018)
  • Author(s): Koyasu Sho、Kobayashi Minoru、Goto Yoko、Hiraoka Masahiro、Harada Hiroshi
  • Journal Title: Cancer Science Volume: 109 Pages: 560-571
  • DOI: 10.1111/cas.13483
  • NAID: 120006454672
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Clinical features of otolith organ-specific vestibular dysfunction. (2018)
  • Author(s): Fujimoto Chisato、Suzuki Sayaka、Kinoshita Makoto、Egami Naoya、Sugasawa Keiko、Iwasaki Shinichi
  • Journal Title: Clin Neurophysiol Volume: 129 Pages: 238-245
  • DOI: 10.1016/j.clinph.2017.11.006
  • Peer Reviewed
• [Journal Article] Subclinical maternal depressive symptoms modulate right inferior frontal response to inferring affective mental states of adults but not of infants. (2018)
  • Author(s): Shimada K, Kasaba R, Fujisawa TX, Sakakibara N, Takiguchi S, Tomoda A
  • Journal Title: Journal of Affective Disorders Volume: 229 Pages: 32-40
  • DOI: 10.1016/j.jad.2017.12.031
  • Peer Reviewed / Open Access
• [Journal Article] Roles of irisin in the linkage from muscle to bone during mechanical unloading in mice. (2018)
  • Author(s): Kawao Naoyuki、Moritake Akihiro、Tatsumi Kohei、Kaji Hiroshi
  • Journal Title: Calcif Tissue Int. Volume: ? Pages: 24-34
  • DOI: 10.1007/s00223-018-0387-3
  • Peer Reviewed / Open Access
• [Journal Article] Comparison among ultrasonic, electrical apparatus, and toxic chemicals for vestibular lesion in mice (2018)
  • Author(s): Yamaoka Yusuke、Abe Chikara、Morita Hironobu
  • Journal Title: Journal of Neuroscience Methods Volume: 295 Pages: 58-67
  • DOI: 10.1016/j.jneumeth.2017.11.021
  • Peer Reviewed / Open Access
• [Journal Article] Effects of hypergravity on the gene levels in anti-gravity muscle and bone through the vestibular system in mice (2018)
  • Author(s): Kawao N, Morita H, Nishida K, Obata K, Tatsumi K, Kaji H.
  • Journal Title: J Physiol Sci Volume: － Pages: 609-616
  • DOI: 10.1007/s12576-017-0566-4
  • NAID: 40021645358
  • Peer Reviewed
• [Journal Article] Increased oxytocin-monomeric red fluorescent protein 1 fluorescent intensity with urocortin-like immunoreactivity in the hypothalamo-neurohypophysial system of aged transgenic rats. (2018)
  • Author(s): Ohno Shigeo、Hashimoto Hirofumi、Fujihara Hiroaki、Fujiki Nobuhiro、Yoshimura Mitsuhiro、Maruyama Takashi、Motojima Yasuhito、Saito Reiko、Ueno Hiromichi、Sonoda Satomi、Ohno Motoko、Umezu Yuichi、Hamamura Akinori、Saeki Satoru、Ueta Yoichi
  • Journal Title: Neurosci Res. Volume: 128 Pages: 40-49
  • DOI: 10.1016/j.neures.2017.08.001
  • Peer Reviewed / Open Access
• [Journal Article] Promoting Stem Sap Flow of Sweetpotatoes under Low Gravity with Forced Air Movements (2018)
  • Author(s): Tokuda, A., Kitaya, Y., Hirai, H., Yano, S
  • Journal Title: AEROSPACE TECHNOLOGY JAPAN Volume: 16(1) Issue: 1 Pages: 53-56
  • DOI: 10.2322/tastj.16.53
  • NAID: 130006301931
  • Peer Reviewed
• [Journal Article] A New System for Three-dimensional Clinostat Synchronized X-irradiation with a High-speed Shutter for Space Radiation Research (2017)
  • Author(s): Ikeda H, Hidema J and Takahashi A et al.
  • Journal Title: Biol. Sci. Space Volume: 30 Issue: 0 Pages: 8-16
  • DOI: 10.2187/bss.30.8
  • NAID: 130005306533
  • Year and Date: 2017-01-31
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle (2017)
  • Author(s): Sakaue-Sawano Asako、Yo Masahiro、Komatsu Naoki、Hiratsuka Toru、Kogure Takako、Hoshida Tetsushi、Goshima Naoki、Matsuda Michiyuki、Miyoshi Hiroyuki、Miyawaki Atsushi
  • Journal Title: Mol. Cell Volume: 68 Pages: 626-640
  • DOI: 10.1016/j.molcel.2017.10.001
  • Peer Reviewed
• [Journal Article] Activation of the hypothalamic feeding centre upon visual prey detection (2017)
  • Author(s): Muto Akira、Lal Pradeep、Ailani Deepak、Abe Gembu、Itoh Mari、Kawakami Koichi
  • Journal Title: Nature Communications Volume: 8 Pages: 15029-15029
  • DOI: 10.1038/ncomms15029
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice. (2017)
  • Author(s): Oishi Yo、Xu Qi、Wang Lu、Zhang Bin-Jia、Takahashi Koji、Takata Yohko、Luo Yan-Jia、Cherasse Yoan、Schiffmann Serge N.、de Kerchove d’Exaerde Alban、Urade Yoshihiro、Qu Wei-Min、Huang Zhi-Li、Lazarus Michael
  • Journal Title: Nat. Commun Volume: 8 Pages: 1-12
  • DOI: 10.1038/s41467-017-00781-4
  • NAID: 120006355834
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus (2017)
  • Author(s): Yoshida Yuki、Koutsovoulos Georgios、Laetsch Dominik R.、Stevens Lewis、Kumar Sujai、Horikawa Daiki D.、Ishino Kyoko、Komine Shiori、Kunieda Takekazu、Tomita Masaru、Blaxter Mark、Arakawa Kazuharu
  • Journal Title: PLOS Biology Volume: 15
  • DOI: 10.1371/journal.pbio.2002266
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A novel perivascular cell population in the zebrafish brain (2017)
  • Author(s): Galanternik Marina Venero、Castranova Daniel、Gore Aniket V、Blewett Nathan H、Jung Hyun Min、Stratman Amber N、Kirby Martha R、Iben James、Miller Mayumi F、Kawakami Koichi、Maraia Richard J、Weinstein Brant M
  • Journal Title: eLife Volume: 6
  • DOI: 10.7554/elife.24369
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Moran’s I quantifies spatio-temporal pattern formation in neural imaging data (2017)
  • Author(s): Schmal Christoph、Myung Jihwan、Herzel Hanspeter、Bordyugov Grigory
  • Journal Title: Bioinformatics Volume: 33 Pages: 3072-3079
  • DOI: 10.1093/bioinformatics/btx351
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Arsenic-mediated hyperpigmented skin via NF-kappa B/Endothelin1 signaling in an originally developed hairless mouse model (2017)
  • Author(s): Yajima I, Kumasaka MY, Iida M, Osino R, Tanihata H, Al Hossain A MM, Ohgami N, Kato M.
  • Journal Title: Archives Toxicology Volume: 91 Pages: 3507-16
  • DOI: 10.1007/s00204-017-1975-0
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The emerging roles of the ubiquitination/deubiquitination system in tumor radioresistance regarding DNA damage responses, cell cycle regulation, hypoxic responses, and antioxidant properties: Insight into the development of novel radiosensitizing strategies (2017)
  • Author(s): Goto Yoko、Koyasu Sho、Kobayashi Minoru、Harada Hiroshi
  • Journal Title: Mutation Research Volume: 803-805 Pages: 76-81
  • DOI: 10.1016/j.mrfmmm.2017.07.007
  • Peer Reviewed
• [Journal Article] Neurotransmitters and neuropeptides in gonadal steroid receptor-expressing cells in medial preoptic area subregions of the male mouse (2017)
  • Author(s): Tsuneoka Yousuke、Yoshida Sachine、Takase Kenkichi、Oda Satoko、Kuroda Masaru、Funato Hiromasa
  • Journal Title: Scientific Reports Volume: 7 Pages: 1-13
  • DOI: 10.1038/s41598-017-10213-4
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Nuclear factor (erythroid derived 2)-like 2 activation increases exercise endurance capacity via redox modulation in skeletal muscles. (2017)
  • Author(s): Oh S, Komine S, Warabi E, Akiyama K, Ishii A, Ishige K, Mizokami Y, Kuga K, Horie M, Miwa Y, Iwawaki T, Yamamoto M, Shoda J
  • Journal Title: Sci Rep. Volume: 7 Pages: 12902-12902
  • DOI: 10.1038/s41598-017-12926-y
  • NAID: 120006355828
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Activation of endogenous arginine vasopressin neurons inhibit food intake: by using a novel transgenic rat line with DREADDs system. (2017)
  • Author(s): Yoshimura Mitsuhiro、Nishimura Kazuaki、Nishimura Haruki、Sonoda Satomi、Ueno Hiromichi、Motojima Yasuhito、Saito Reiko、Maruyama Takashi、Nonaka Yuki、Ueta Yoichi
  • Journal Title: Sci Rep. Volume: 7 Pages: 1-10
  • DOI: 10.1038/s41598-017-16049-2
  • Peer Reviewed / Open Access
• [Journal Article] Oral exposure to arsenic causes hearing loss in young people aged 12-29 years and in young mice (2017)
  • Author(s): Li X, Ohgami N, Omata Y, Yajima I, Iida M, Oshino R, Ohnuma S, Ahsan N, Akhand AA, Kato M.
  • Journal Title: Scientific Reports Volume: 7 Pages: 6844-6844
  • DOI: 10.1038/s41598-017-06096-0
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization (2017)
  • Author(s): Nakashima Ryota、Goto Yoko、Koyasu Sho、Kobayashi Minoru、Morinibu Akiyo、Yoshimura Michio、Hiraoka Masahiro、Hammond Ester M.、Harada Hiroshi
  • Journal Title: Scientific Reports Volume: 7 Pages: 6879-6879
  • DOI: 10.1038/s41598-017-06605-1
  • NAID: 120006355750
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Heat-Induced Calcium Leakage Causes Mitochondrial Damage inCaenorhabditis elegansBody-Wall Muscles (2017)
  • Author(s): Momma Kenta、Homma Takashi、Isaka Ruri、Sudevan Surabhi、Higashitani Atsushi
  • Journal Title: Genetics Volume: 206 Pages: 1985-1994
  • DOI: 10.1534/genetics.117.202747
  • Peer Reviewed / Open Access
• [Journal Article] Cryptoendolithic Antarctic Black Fungus Cryomyces antarcticus Irradiated with Accelerated Helium Ions: Survival and Metabolic Activity, DNA and Ultrastructural Damage (2017)
  • Author(s): Claudia Pacelli, Ralf Moeller, Akira Fujimori et al.
  • Journal Title: Frontiers in Microbiology Volume: 8 Pages: 2002-2002
  • DOI: 10.3389/fmicb.2017.02002
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes (2017)
  • Author(s): Kobayashi Minoru、Morinibu Akiyo、Koyasu Sho、Goto Yoko、Hiraoka Masahiro、Harada Hiroshi
  • Journal Title: The FEBS Journal Volume: 284 Pages: 3804-3816
  • DOI: 10.1111/febs.14280
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Growth responses of wasabi plantlets under different temperature regimes during photoautotrophic micropropagation (2017)
  • Author(s): Hoang NN, Kitaya Y, Endo R et al.
  • Journal Title: Eco-Engineering Volume: 29(4) Pages: 125-129
  • Peer Reviewed
• [Journal Article] Running training experience attenuates disuse atrophy in fast-twitch skeletal muscles of rats (2017)
  • Author(s): Nakamura Keisuke、Ohsawa Ikumi、Masuzawa Ryo、Konno Ryotaro、Watanabe Atsuya、Kawano Fuminori
  • Journal Title: Journal of Applied Physiology Volume: 123 Pages: 902-913
  • DOI: 10.1152/japplphysiol.00289.2017
  • Peer Reviewed / Open Access
• [Journal Article] Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice. (2017)
  • Author(s): Konishi H, Ohgami N, Matsushita A, Kondo Y, Aoyama Y, Kobayashi M, Nagai T, Ugawa S, Yamada K, Kato M, Kiyama H
  • Journal Title: Neuroscience. Volume: 印刷中 Pages: 15-23
  • DOI: 10.1016/j.neuroscience.2017.03.028
  • NAID: 120006331816
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Upregulation of matrix metalloproteinase triggers transdifferentiation of retinal pigmented epithelial cells in Xenopus laevis: A Link between inflammatory response and regeneration (2017)
  • Author(s): Naitoh Hanako、Suganuma Yukari、Ueda Yoko、Sato Takahiko、Hiramuki Yosuke、Fujisawa-Sehara Atsuko、Taketani Shigeru、Araki Masasuke
  • Journal Title: Developmental Neurobiology Volume: 77 Pages: 1086-1100
  • DOI: 10.1002/dneu.22497
  • Peer Reviewed / Open Access
• [Journal Article] Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro (2017)
  • Author(s): Kumasaka MY, Yajima I, Ohgami N, Ninomiya H, Iida M, Li X, Oshino R, Tanihata H, Yoshinaga M, Kato M.
  • Journal Title: Neurotoxicity Research Volume: 32 Pages: 661-670
  • DOI: 10.1007/s12640-017-9783-0
  • NAID: 120006367974
  • Peer Reviewed
• [Journal Article] Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptor (2017)
  • Author(s): Yamamoto Naoshi、Ohrui Sayaka、Okada Takahiro、Yata Masahiro、Saitoh Tsuyoshi、Kutsumura Noriki、Nagumo Yasuyuki、Irukayama-Tomobe Yoko、Ogawa Yasuhiro、Ishikawa Yukiko、Watanabe Yurie、Hayakawa Daichi、Gouda Hiroaki、Yanagisawa Masashi、Nagase Hiroshi
  • Journal Title: Bioorganic & medicinal chemistry letters Volume: 27 Pages: 4176-4179
  • DOI: 10.1016/j.bmcl.2017.07.011
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Low and High LET Ionizing Radiation-Induced Delayed Homologous Recombination Persists for Two Weeks Before Resolving. (2017)
  • Author(s): Allen Christopher P.、Hirakawa Hirokazu、Nakajima Nakako Izumi、Moore Sophia、Nie Jingyi、Sharma Neelam、Sugiura Mayumi、Hoki Yuko、Araki Ryoko、Abe Masumi、Okayasu Ryuichi、Fujimori Akira、Nickoloff Jac A.
  • Journal Title: Radiation Research Volume: 188 Pages: 82-93
  • DOI: 10.1667/rr14748.1
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Radiation exposure enhances hepatocyte proliferation in neonatal mice but not in adult mice (2017)
  • Author(s): Shang Yi、Sawa Yurika、Blyth Benjamin J.、Tsuruoka Chizuru、Nogawa Hiroyuki、Shimada Yoshiya、Kakinuma Shizuko
  • Journal Title: Radiation Research Volume: 188 Pages: 235-241
  • DOI: 10.1667/rr14563.1
  • Peer Reviewed
• [Journal Article] Antiangiogenic agent sunitinib induces epithelial to mesenchymal transition and accelerates motility of colorectal cancer cells (2017)
  • Author(s): Chisato Tomida, Naoko Yamagishi, Hikaru Nagano, Takayuki Uchida, Ayako Ohno, Katsuya Hirasaka, Takeshi Nikawa, Shigetada Teshima-Kondo
  • Journal Title: J. Med. Invest. Volume: 64 Issue: 3.4 Pages: 250-254
  • DOI: 10.2152/jmi.64.250
  • NAID: 130006105181
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Regorafenib induces adaptive resistance of colorectal cancer cells via inhibition of vascular endothelial growth factor receptor (2017)
  • Author(s): Tomida Chisato、Nagano Hikaru、Yamagishi Naoko、Uchida Takayuki、Ohno Ayako、Hirasaka Katsuya、Nikawa Takeshi、Teshima-Kondo Shigetada
  • Journal Title: J. Med. Invest. Volume: 64 Issue: 3.4 Pages: 262-265
  • DOI: 10.2152/jmi.64.262
  • NAID: 130006105177
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Oxygen Enhancement Ratio in Radiation-Induced Initial DSBs by an Optimized Flow Cytometry-based Gamma-H2AX Analysis in A549 Human Cancer Cells. (2017)
  • Author(s): Sunada Shigeaki、Hirakawa Hirokazu、Fujimori Akira、Uesaka Mitsuru、Okayasu Ryuichi
  • Journal Title: Radiation Research Volume: 188 Pages: 591-594
  • DOI: 10.1667/rr14824.1
  • Peer Reviewed
• [Journal Article] Investigation of the relative biological effectiveness and uniform isobiological killing effects of irradiation with a clinical carbon SOBP beam on DNA repair deficient CHO cells. (2017)
  • Author(s): Sunada Shigeaki、Cartwright Ian M.、Hirakawa Hirokazu、Fujimori Akira、Uesaka Mitsuru、Kato Takamitsu A.
  • Journal Title: Oncology Letters Volume: 13 Pages: 4911-4916
  • DOI: 10.3892/ol.2017.6072
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Simple generation of hairless mice for in vivo imaging. (2017)
  • Author(s): Hoshino Y, Mizuno S, Kato K, Mizuno-Iijima S, Tanimoto Y, Ishida M, Kajiwara N, Sakasai T, Miwa Y, Takahashi S, Yagami KI, Sugiyama F
  • Journal Title: Exp. Anim. Volume: 66(4) Issue: 4 Pages: 437-445
  • DOI: 10.1538/expanim.17-0049
  • NAID: 130006187194
  • Peer Reviewed / Open Access
• [Journal Article] Research and development of radioprotective agents: A mini-review (2017)
  • Author(s): Fazliana Mohd Saaya, Takanori Katsube, Yi Xie, Kaoru Tanaka, Kazuko Fujita, Bing Wang
  • Journal Title: International Journal of Radiology Volume: 4 (2-3) Pages: 128-138
  • Peer Reviewed
• [Journal Article] Forward genetic analysis of sleep in randomly mutagenized mice. (2017)
  • Author(s): Funato H, et al.
  • Journal Title: Nature. Volume: 539(7629) Issue: 46 Pages: 378-383
  • DOI: 10.1038/nature20142
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein (2017)
  • Author(s): Hashimoto T, Horikawa DD, Saito Y, Kuwahara H, Kozuka-Hata H, Shin-I T, Minakuchi Y, Ohishi K, Motoyama A, Aizu T, Enomoto A, Kondo K, Tanaka S, Hara Y, Koshikawa S, Sagara H, Miura T, Yokobori S, Miyagawa K, Suzuki Y, Kubo T, Oyama M, Kohara Y, Fujiyama A, Arakawa K, Katayama T, Toyoda A and Kunieda T
  • Journal Title: Nat Commun. Volume: 7 Pages: 12808-12808
  • DOI: 10.1038/ncomms12808
  • NAID: 120005971035
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Entire photodamaged chloroplasts are transported to the central vacuole by autophagy. (2017)
  • Author(s): Izumi M, Ishida H, Nakamura S and Hidema J
  • Journal Title: The Plant Cell Volume: 29(2) Pages: 377-394
  • DOI: 10.1105/tpc.16.00637
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Moxd1 is a marker for sexual dimorphism in the medial preoptic area, bed nucleus of the stria terminalis and medial amygdala. (2017)
  • Author(s): Tsuneoka Y and Funato H et al.
  • Journal Title: Frontiers in Ｎeuroanatomy Volume: 11 Pages: 1-13
  • DOI: 10.3389/fnana.2017.00026
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Secretome analysis to elucidate metalloprotease-dependent ectodomain shedding of glycoproteins during neuronal differentiation. (2017)
  • Author(s): Tsumagari K, Shirakabe K, Ogura M, Sato F, Ishihama Y and Sehara-Fujisawa A
  • Journal Title: Genes to Cells Volume: 22(2) Pages: 237-244
  • DOI: 10.1111/gtc.12466
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Impact of a simulated gravity load for atmospheric reentry-10 g for 2 minutes-on conscious mouse (2017)
  • Author(s): Morita H, Yamaguchi A, Shiba D, Shirakawa M and Takahashi S
  • Journal Title: J Physiol Sci Volume: Epub ahead of print Pages: 531-537
  • DOI: 10.1007/s12576-017-0526-z
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Design and Synthesis of Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton and their Pharmacologies (2017)
  • Author(s): Nagase H and Yanagisawa M et al.
  • Journal Title: Journal of Medicinal Chemistry Volume: 60 Pages: 1018-1040
  • DOI: 10.1021/acs.jmedchem.6b01418
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system. (2017)
  • Author(s): Ikeda H, Hidema J and Takahashi A et al.
  • Journal Title: Life Sci Space Res (Amst). Volume: 12 Pages: 51-60
  • DOI: 10.1016/j.lssr.2017.01.003
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Risk assessment of neonatal exposure to low frequency noise based on balance in mice. (2017)
  • Author(s): Ohgami N et al.
  • Journal Title: Frontiers in Behavioral Neuroscience Volume: 11 Pages: 30-30
  • DOI: 10.3389/fnbeh.2017.00030
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] denti cation of mutations through dominant screening for obesity using C57BL/6 substrains (2016)
  • Author(s): Hossain MS., Funato H, and Yanagisawa M et al.
  • Journal Title: Scientific Report Volume: 6 Pages: 1-15
  • DOI: 10.1038/srep32453
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Long-term exposure to microgravity impairs vestibulo-cardiovascular reflex (2016)
  • Author(s): Morita H, Abe C and Tanaka K
  • Journal Title: Scientific Reports Volume: 6 Pages: 33405-33405
  • DOI: 10.1038/srep33405
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Acute transcriptional up-regulation specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity. (2016)
  • Author(s): Chatani M et al.
  • Journal Title: Scientific Reports Volume: 6 Pages: 1-14
  • DOI: 10.1038/srep39545
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Manganese-mediated acceleration of age-related hearing loss in mice (2016)
  • Author(s): Ohgami N et al.
  • Journal Title: Sci Rep Volume: 6 Pages: 36306-36306
  • DOI: 10.1038/srep36306
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] The vestibular system is critical for the changes in muscle and bone induced by hypergravity in mice. (2016)
  • Author(s): Kawao N, Morita H, Obata K, Tamura Y, Okumoto K and Kaji H
  • Journal Title: Physiol Rep. Volume: 4(19) Pages: 12979-12979
  • DOI: 10.14814/phy2.12979
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator. (2016)
  • Author(s): Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, Yoshinaga R, Kurihara M, Demizu Y, Yasuda H, Yagi S, Wu G, Matsumoto M, Sakamoto R, Yoshida N, Penninger JM, Kobayashi Y, Inoue J, Akiyama T.
  • Journal Title: J Exp Med Volume: 213 Pages: 1441-1458
  • DOI: 10.1084/jem.20151780
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis. (2016)
  • Author(s): Harada H et al.
  • Journal Title: Oncotargets Volume: 7(40) Pages: 11670-11670
  • DOI: 10.18632/oncotarget.11670
  • NAID: 120005980808
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage without developmental defects (2016)
  • Author(s): Tokumasu Y, Iida A, Wang Z, Ansai S, Kinoshita M, and Sehara-Fujisawa A
  • Journal Title: Development, Growth & Differentiation Volume: 58(4) Pages: 409-421
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Novel roles of FKBP5 in muscle alteration induced by gravity change in mice. (2016)
  • Author(s): Shimode T, Kawao N, Tamura Y, Morita H and Kaji H
  • Journal Title: Biochem Biophys Res Commun. Volume: 479 Pages: 602-606
  • DOI: 10.1016/j.bbrc.2016.09.126
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Characterization of Fungi Isolated from the Equipment Used in the International Space Station or Space Shuttle (2016)
  • Author(s): Satoh K, Yamazaki T and Makimura K et al.
  • Journal Title: Microbiology and Immunology Volume: 60(5) Pages: 295-302
  • DOI: 10.1111/1348-0421.12375
  • NAID: 40020832338
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Fluorescence-activated cell sorting and gene expression profiling of GFP-positive cells from transgenic zebrafish lines (2016)
  • Author(s): Tanabe H and Kawakami K et al.
  • Journal Title: Methods in Molecular Biology Volume: 1451 Pages: 93-106
  • DOI: 10.1007/978-1-4939-3771-4_7
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans. (2016)
  • Author(s): Higashibata A., Hashizume T., Nemoto K., Higashitani N., Etheridge T., Mori C., Harada S., Sugimoto T., Szewczyk NJ., Baba SA., Mogami Y., Fukui K., Higashitani A.
  • Journal Title: npj Microgravity Volume: 2 Pages: 15022-15022
  • DOI: 10.1038/npjmgrav.2015.22
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Fluid dynamics alter Caenorhabditis elegans body length via TGF-β/DBL-1 neuromuscular signaling. (2016)
  • Author(s): Harada S., Hashizume T., Nemoto K., Shao Z., Higashitani N., Etheridge T., Szewczyk NJ., Fukui K., Higashibata A., Higashitani A.
  • Journal Title: npj Microgravity Volume: 2 Pages: 16006-16006
  • DOI: 10.1038/npjmgrav.2016.6
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] The relationship between widespread changes in gravity and cerebral blood flow. (2016)
  • Author(s): Ogawa Y, Yanagida R, Ueda K, Aoki K, Iwasaki K
  • Journal Title: Environmental Health and Preventive Medicine Volume: in press
  • DOI: 10.1007/s12199-016-0513-7
  • NAID: 210000000435
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Intrathecal morphine-3-glucuronide-induced nociceptive behavior via Delta-2 opioid receptors in the spinal cord (2016)
  • Author(s): Takaaki Komatsu, Soh Katsuyama, Hiroshi Nagase, Hirokazu Mizoguchi, Chikai Sakurada, Minoru Tsuzuki, Shinobu Sakurada, Tsukasa Sakurada
  • Journal Title: Pharmacol. Biochem. Be. Volume: 140 Pages: 68-74
  • DOI: 10.1016/j.pbb.2015.10.010
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Opioid System in the Lateral Hypothalamus Regulate Feeding Behavior Through Orexin and GABA Neurons (2016)
  • Author(s): Ardianto C, Yonemochi N, Yamamoto S, Yang L, Takenoya F, Shioda S, Nagase H, Ikeda H, Kamei J.
  • Journal Title: NeuroScience Volume: 320 Pages: 183-193
  • DOI: 10.1016/j.neuroscience.2016.02.002
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] High-fat diet feeding alters olfactory-, social- and reward-related behaviors of mice independent of obesity (2016)
  • Author(s): Takase K, Tsuneoka Y, Oda S, Kuroda M, Funato H
  • Journal Title: Obesity (Silver Spring, Md.) Volume: 4 Pages: 886-894
  • DOI: 10.1002/oby.21441
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Sleep as a biological problem: an overview of frontiers in sleep research. (2016)
  • Author(s): Kanda T, Tsujino N, Kuramoto E, Koyama Y, Susaki EA, Chikahisa S, Funato H
  • Journal Title: The Journal of Physiological Sciences Volume: 66 Pages: 1-13
  • DOI: 10.1007/s12576-015-0414-3
  • NAID: 40020697820
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Nighttime Administration of Nicotine Improves Hepatic Glucose Metabolism via the Hypothalamic Orexin System in Mice (2016)
  • Author(s): Tsuneki H, Nagata T, Fujita M, Kon K, Wu N, Takatsuki M, Yamaguchi K, Wada T, Nishijo H, Yanagisawa M, Sakurai T, Sasaoka T.
  • Journal Title: Endocrinology Volume: 157 Pages: 195-206
  • DOI: 10.1210/en.2015-1488
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Plant nuclei move to escape ultraviolet-induced DNA damage and cell death (2016)
  • Author(s): Iwabuchi K., Hidema J., Tamura K., Takagi S., and Hara-Nishimura I.
  • Journal Title: Plant Physiol. Volume: 170 Issue: 2 Pages: 678-685
  • DOI: 10.1104/pp.15.01400
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A critical role of Dectin-1 in hypersensitivity pneumonitis. (2016)
  • Author(s): Higashino-Kameda M, Yabe-Wada T, Matsuba S, Takeda K, Anzawa K, Mochizuki T, Makimura K, Saijo S, Iwakura Y, Toga H, Nakamura A
  • Journal Title: Inflamm Res. Volume: 65 Pages: 235-244
  • DOI: 10.1007/s00011-015-0910-1
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Comprehensive analysis of the skin fungal microbiota of astronauts during a half-year stay at the International Space Station (2016)
  • Author(s): Sugita T, Yamazaki T, Makimura K, Cho O, Yamada S, Ohshima H, Mukai C
  • Journal Title: Medical Mycology Volume: published online Pages: 232-239
  • DOI: 10.1093/mmy/myv121
  • Peer Reviewed / Open Access
• [Journal Article] Phylogenetic analysis of dermatophyte species using DNA sequence polymorphism in calmodulin gene (2016)
  • Author(s): Ahmadi B, Mirhendi H, Makimura K, de Hoog GS, Shidfar MR, Nouripour-Sisakht S, Jalalizand N
  • Journal Title: Med Mycol Volume: published online
  • DOI: 10.1093/mmy/myw004
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Fatal Cyberlindnera fabianii fungemia in a patient with mixed phenotype acute leukemia after umbilical cord blood transplantation (2016)
  • Author(s): Katagiri S, Gotoh M, Tone K, Akahane D, Ito Y, Ohyashiki K, Makimura K
  • Journal Title: Int J Hematol Volume: published online
  • DOI: 10.1007/s12185-016-1953-y
  • Peer Reviewed
• [Journal Article] Epidemiological aspects of Dermatophytosis in Khusestan, southwestern Iran, an update (2016)
  • Author(s): Razaei-Matehkolaei A, Rafiei A, Makimura K, Graser Y, Gharghani M, Sadeghi-Nejad B
  • Journal Title: Mycopathologia Volume: published online
  • DOI: 10.1007/s11046-016-9990-x
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Mest but not miR-335 affects skeletal muscle growth and regeneration (2015)
  • Author(s): Hiramuki Y, Sato T, Furuta Y, Surani A, Sehara-Fujisawa A
  • Journal Title: PLoS One Volume: 10
  • DOI: 10.1371/journal.pone.0130436
  • NAID: 120005756262
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] High-resolution live imaging reveals axon-glia interactions during peripheral nerve injury and repair (2015)
  • Author(s): Xiao Y, Faucherre A, Pola-Morell L, Heddleston J, Liu T, Chew T, Sato F, Sehara-Fujisawa A, Kawakami K, Lopez-Schier H
  • Journal Title: Disease Models & Mechanisms Volume: 8 Pages: 553-564
  • DOI: 10.1242/dmm.018184
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells. (2015)
  • Author(s): Shoji E, Sakurai H, Nishino T, Nakahata T, Heike T, Awaya T, Fujii N, Manabe Y, Matsuo M, Sehara-Fujisawa A
  • Journal Title: Scientific Reports. Volume: 5 Pages: 12831-12831
  • DOI: 10.1038/srep12831
  • NAID: 120005649326
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Molecular dynamics study on protein–water interplay in the mechanogating of the bacterial mechanosensitive channel MscL (2015)
  • Author(s): Sawada Y, Sokabe M
  • Journal Title: Eur J Biophys Volume: 44 Pages: 531-43
  • DOI: 10.1007/s00249-015-1065-2
  • Peer Reviewed / Open Access
• [Journal Article] Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes (2015)
  • Author(s): Nomura T, Cox CD, Bavi N, Sokabe M and Martinac B
  • Journal Title: FASEB J Volume: 29 Pages: 4334-4345
  • DOI: 10.1096/fj.15-275198
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Ion Channels Activated by Mechanical Forces in Bacterial and Eukaryotic Cells (2015)
  • Author(s): Sokabe M, Sawada M, Kobayashi T
  • Journal Title: Subcell Biochem: high Pressure Bioscience-Basic Concepts, Applications and Frontiers Volume: 72 Pages: 613-26
  • DOI: 10.1007/978-94-017-9918-8_28
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice. (2015)
  • Author(s): Tateishi R, Akiyama N, Miyauchi M, Yoshinaga R, Sasanuma H, Kudo T, Shimbo M, Shinohara M, Obata K, Inoue J, Shirakawa M, Shiba D, Asahara H, Yoshida N, Takahashi S, Morita H, Akiyama T
  • Journal Title: PLoS One Volume: 10 Pages: 1-17
  • DOI: 10.1371/journal.pone.0141650
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Feasibility of a Short-Arm Centrifuge for Mouse Hypergravity Experiments. (2015)
  • Author(s): Morita H, et al.
  • Journal Title: PLoS One Volume: 10(7): e133981 Pages: 1-14
  • DOI: 10.1371/journal.pone.0133981
  • NAID: 120005656590
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Role of osteoclasis in the heterotopic ossification enhanced by fobrodysplasia ossificans progressiva-related activin-like kinase 2 mutation in mice (2015)
  • Author(s): Kawao N, Yano M, Tamura Y, Okumoto K, Okada K, Kaji H
  • Journal Title: J Bone Miner Metab Volume: epub
  • Peer Reviewed
• [Journal Article] Clinical charasteristics of patients with abnornal ocular/cervical vestibular evoked myogenic potentials in the presence of normal caloric responses (2015)
  • Author(s): Iwasaki S, Fujimoto C, Kinoshita M, Kamogashira T, Egami N, Yamasoba T
  • Journal Title: Ann Otol Rhinol Laryngol Volume: 124 Pages: 458-65
  • Peer Reviewed
• [Journal Article] The effect of aging on the center-of-pressure power spectrum in foam posturography (2015)
  • Author(s): Fujimoto C, Egami N, Demura S, Yamasoba T, Iwasaki S.
  • Journal Title: Neuroscience letters Volume: 585 Pages: 92-7
  • DOI: 10.1016/j.neulet.2014.11.033
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Transformation of naltrexone into mesembrane and investigation of the binding properties of its intermediate derivatives to opioid receptors (2015)
  • Author(s): Konoura K, Fujii H, Imaide S, Gouda H, Hirayama S, Hirono S, Nagase H
  • Journal Title: Bioorg. Med. Chem. Volume: 23 Pages: 439-448
  • DOI: 10.1016/j.bmc.2014.12.032
  • NAID: 120005555623
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo. (2015)
  • Author(s): Masami Suzuki, Fumiko Chiwaki, Yumi Sawada, Maho Ashikawa, Kazuhiko Aoyagi, Takeshi Fujita, Kazuyoshi Yanagihara, Masayuki Komatsu, Minoru Narita, Tsutomu Suzuki, Hiroshi Nagase, Ryoji Kushima, Hiromi Sakamoto, Takeo Fukagawa, Hitoshi Katai, Hitoshi Nakagama, Teruhiko Yoshida, Yasuhito Uezono, Hiroki Sasaki
  • Journal Title: PLoS One. Volume: 10(4) Pages: 1-18
  • DOI: 10.1371/journal.pone.0123407
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Naltrindole derivatives with fluorinated ethyl substituents on 17-nitrogen as delta opioid receptor inverse agonist (2015)
  • Author(s): Nemoto T, Iihara Y, Hirayama S, Iwai T, Higashi E, Fujii H, Nagase H
  • Journal Title: Bioorg Med Chem Lett Volume: 25 Pages: 2927-30
  • DOI: 10.1016/j.bmcl.2015.05.038
  • Peer Reviewed
• [Journal Article] Naltrindole derivatives with fluorinated ethyl substituents on 17-nitrogen as δ opioid receptor inverse agonist (2015)
  • Author(s): Kutsumura, N.; Nakajima, R.; Koyama, Y.; Miyata, Y.; Saitoh, T.; Yamamoto, N.; Iwata, S.; Fujii, H.; Nagase, H.
  • Journal Title: Bioorg. Med. Chem. Lett Volume: 25 Pages: 4890-2
  • DOI: 10.1016/j.bmcl.2015.06.002
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Inhibition of opioid systems in the hypothalamus as well as the mesolimbic area suppresses feeding behavior of mice (2015)
  • Author(s): Ikeda H, Ardianto C, Yonemochi N, Yang L, Ohashi T, Ikegami M, Nagase H, Kamei J
  • Journal Title: NeuroScience Volume: 311 Pages: 9-21
  • DOI: 10.1016/j.neuroscience.2015.10.002
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Design and synthesis of non-peptide, selective orexin receptor 2 agonists (2015)
  • Author(s): Nagahara T, Saitoh T, Kutsumura N, Irukayama-Tomobe Y, Ogawa Y, Kuroda D, Gouda H, Kumagai H, Fujii H, Yanagisawa M, Nagase H
  • Journal Title: J Med Chem. Volume: 58 Pages: 7931-37
  • DOI: 10.1021/acs.jmedchem.5b00988
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: Part 5, novel pentacyclic propellane derivatives with a 6-amide side chain (2015)
  • Author(s): Nakajima R, Yamamoto N, Hirayama S, Iwai T, Saitoh A, Nagumo Y, Fujii H, Nagase H.
  • Journal Title: Bioorg. Med. Chem. Volume: 23 Pages: 6271-6279
  • DOI: 10.1016/j.bmc.2015.08.036
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Endothelin-1 as a master regulator of whole-body Na+ homeostasis (2015)
  • Author(s): Speed JS, Heimlich JB, Hyndman KA, Fox BM, Patel V, Yanagisawa M, Pollock JS, Titze JM, Pollock DM
  • Journal Title: FASEB J Volume: 29 Pages: 4937-44
  • DOI: 10.1096/fj.15-276584
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Functional ETA-ETB receptor cross-talk in basilar artery in situ from ETB receptor deficient rats (2015)
  • Author(s): Yoon S, Gariepy CE, Yanagisawa M, Zuccarello M, Rapoport RM
  • Journal Title: J Cardiovasc Pharmacol Volume: epub
  • Peer Reviewed
• [Journal Article] 長期宇宙滞在時に解決すべき医学的課題～循環制御関連を中心に～ (2015)
  • Author(s): 古川聡
  • Journal Title: 循環制御 Volume: 36 Pages: 66-8
  • Open Access
• [Journal Article] UV-B-Induced CPD Photolyase Gene Expression is Regulated by UVR8-Dependent and -Independent Pathways in Arabidopsis (2015)
  • Author(s): Li N, Teranishi M, Yamaguchi Ｈ, Matsushita T, Watahiki MK, Tsuge T, Li SS, Hidema J
  • Journal Title: Plant Cell Physiol. Volume: 56 Pages: 2014-2023
  • DOI: 10.1093/pcp/pcv121
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] From Arabidopsis to cereal crops: Conservation of chloroplast protein degradation by autophagy indicates its fundamental role in plant productivity (2015)
  • Author(s): Izumi M, Hidema J, Ishida H
  • Journal Title: Plant Signal Behav. Volume: 10
  • DOI: 10.1080/15592324.2015.1101199
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells (2015)
  • Author(s): Ma H, Takahashi A, Yoshida Y, Adachi A, Kanai T, Ohno T, Nakano T.
  • Journal Title: Radiat Oncol Volume: 10 Pages: 225-225
  • DOI: 10.1186/s13014-015-0536-z
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Targeting of Carbon Ion-Induced G2 Checkpoint Activation in Lung Cancer Cells Using Wee-1 Inhibitor MK-1775 (2015)
  • Author(s): Ma H, Takahashi A, Sejimo Y, Adachi A, Kubo N, Isono M, Yoshida Y, Kanai T, Ohno T, Nakano T.
  • Journal Title: Radiat Res Volume: 184 Pages: 660-669
  • DOI: 10.1667/rr14171.1
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Genetic and phenotypic analyses of Calcineurin A subunit in Arthroderma vanbreuseghemii (2015)
  • Author(s): Alshahni MM, Shimizu K, Yoshimoto M, Yamada T, Nishiyama Y, Arai T, Makimura K
  • Journal Title: Med Mycol Volume: 54 Pages: 207-18
  • DOI: 10.1093/mmy/myv088
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Dermatophytosis due to Microsporum incurvatum: notification and identification of a neglected pathogenic species (2015)
  • Author(s): Rezaei-Matehkolaei A, Makimura K, Graser Y, Seyedmousavi S, Abastabar M, Rafiei A, Zhan P, Ronagh A, Jafarpour S
  • Journal Title: Mycopathologia Volume: 181 Pages: 107-13
  • DOI: 10.1007/s11046-015-9946-6
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Microbes and crewed space habitat (2015)
  • Author(s): Yamaguchi N, Nasu M
  • Journal Title: J Dis Res Volume: 10 Pages: 1022-4
  • NAID: 130007673462
• [Journal Article] Microbial observatory research in the International Space Station and Japanese Experiment Module "Kibo" (2015)
  • Author(s): Shirakawa M, Tanigaki F, Yamazaki T
  • Journal Title: J Dis Res Volume: 10 Pages: 1025-30
• [Journal Article] Significance of changes in the skin fungal microbiomes of astronauts staying on the International Space Station (2015)
  • Author(s): Sugita T, Cho O
  • Journal Title: J Dis Res Volume: 10 Pages: 1031-4
• [Journal Article] Bacterial Monitoring in the International Space Station (2015)
  • Author(s): Ichijo T, Yamaguchi N, nasu M
  • Journal Title: J Dis Res Volume: 10 Pages: 1035-9
• [Presentation] 新しい溶液内区画化法を用いた「膜なし型」分子ロボットの提案 (2019)
  • Author(s): Masahito Hayashi, Naoki Nakatani, Hiroki Sakuta, Shunsuke Tanaka, Kingo Takiguchi, Kanta Tsumoto, Kenichi Yoshikawa
  • Organizer: 第2回分子ロボティクス年次大会
• [Presentation] TRPC6 plays a critical role in phenotype switching of vascular smooth muscle cells by physical and functional coupling with PTEN via membrane potential (2019)
  • Author(s): 冨田 拓郎
  • Organizer: 第92回日本薬理学会年会
• [Presentation] Importance of receptor-activated Ca2+ influx in wound healing (2019)
  • Author(s): 冨田 拓郎
  • Organizer: 第9回アジア・オセアニア生理学会連合大会（FAOPS2019）
  • Int'l Joint Research
• [Presentation] Physiological and pathophysiological significance of TRPC3-Nox2 coupling in the heart (2019)
  • Author(s): 冨田 拓郎
  • Organizer: 第9回アジア・オセアニア生理学会連合大会（FAOPS2019）
  • Int'l Joint Research
• [Presentation] Towards spatial and temporal control of gene knockout: transgenic approaches (2019)
  • Author(s): Koichi Kawakami
  • Organizer: The 8th Strategic Conference of Zebrafish Investigators
  • Int'l Joint Research
• [Presentation] 大規模マウス睡眠ステージ解析のための深層学習モデルの開発 (2019)
  • Author(s): 山部 剛士, 堀江 和正, 塩川 浩昭, 柳沢 正史, 北川 博之
  • Organizer: 第11回データ工学と情報マネジメントに関するフォーラム(DEIM2019)
• [Presentation] 哺乳類中枢概日時計の神経メカニズム (2019)
  • Author(s): 三枝理博
  • Organizer: 明治大学現象数理学共同研究集会
  • Invited
• [Presentation] Analysis of the central circadian clock in AVP neuron-specific VGAT deficient mice (2019)
  • Author(s): 前島隆司, 長谷川恵美, 津野祐輔, 三枝理博
  • Organizer: 第９回アジア・オセアニア生理学会連合（FAOPS）2019年大会
  • Int'l Joint Research
• [Presentation] 敵対的生成ネットワークを用いたマウスEEGのノイズ削減手法の提案 (2019)
  • Author(s): 住谷 雄樹, 堀江 和正, 塩川 浩昭, 北川 博之
  • Organizer: 第11回データ工学と情報マネジメントに関するフォーラム(DEIM2019)
• [Presentation] PAI-1 is crucial in osteoblastic differentiation of mesenchymal stem cells. (2019)
  • Author(s): Yoshimasa Takafuji, Kohei Tatsumi, Masayoshi Ishida, Naoyuki Kawao, Kiyotaka Okada, Osamu Matsuo, Hiroshi Kaji
  • Organizer: 9th Federation of the Asian and Oceanian Physiological Societies
  • Int'l Joint Research
• [Presentation] Roles of macrophages and PAI-1 in diabetic delayed bone repair in female mice. (2019)
  • Author(s): Naoyuki Kawao, Takeshi Shimoide, Yukinori Tamura, Kiyotaka Okada, Katsumi Okumoto, Shinji Kurashimo, Yoshitaka Horiuchi, Kohei Tatsumi, Osamu Matsuo, Hiroshi Kaji
  • Organizer: 9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
  • Int'l Joint Research
• [Presentation] Dominantly expressed Serpina3n suppresses the phenotypes of osteoblasts of female mice. (2019)
  • Author(s): Masayoshi Ishida,Naoyuki Kawao,Kiyotaka Okada,Kohei Tatsumi,Kazuko Sakai,KazutoNishio,Hiroshi Kaji
  • Organizer: 9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
  • Int'l Joint Research
• [Presentation] PAI-1は間葉系幹細胞から骨芽細胞への分化過程に重要である (2019)
  • Author(s): 高藤義正、辰巳公平、石田昌義、河尾直之、岡田清孝、松尾理、梶博史
  • Organizer: 第18回日本再生医療学会総会
• [Presentation] Fos expression in the hypothalamic nuclei after changes from hypergravity to normal gravity in mice (2019)
  • Author(s): Yoichi Ueta, Mitsuhiro Yoshimura, Satomi Sonoda, Takashi Maruyama, Chikara Abe, Hironobu Morita
  • Organizer: 9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
  • Int'l Joint Research
• [Presentation] Impact of long-term stay in micro-gravity on vestibular function (2019)
  • Author(s): Hironobu Morita, Chikara Abe, Kunihiko Tanaka
  • Organizer: 9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
  • Int'l Joint Research
• [Presentation] 重力変化後のマウス視床下部摂食関連ペプチド遺伝子発現の変化 (2019)
  • Author(s): 園田里美、吉村充弘、橋本弘史、眞田賢哉、西村和朗、西村春来、田中健太郎、上野啓通、丸山 崇、安部 力、森田啓之、上田陽一
  • Organizer: 第14回環境生理学プレコングレス
• [Presentation] 前庭系を介する自律神経調節 (2019)
  • Author(s): 安部 力
  • Organizer: 第1回日本医学会連合「Rising Star」リトリート
  • Invited
• [Presentation] 急速輸液投与による血液希釈を伴う循環血液量増加が頭蓋内圧に与える影響 (2019)
  • Author(s): 倉住拓弥、小川洋二郎、田子智晴、加藤智一、小西透、岩﨑賢一
  • Organizer: 第46回日本集中治療医学会学術集会
• [Presentation] 遠心人工重力装置を用いた過重力環境曝露時の脳血流と脳内酸素飽和度の変化 (2019)
  • Author(s): 小西透、倉住拓弥、加藤智一、田子智晴、柳田亮、小川洋二郎、岩﨑賢一
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] 特別講演「宇宙医学 ～心と体の変化を探る～」 (2019)
  • Author(s): 小川洋二郎
  • Organizer: 第130回 日本心身医学会関東地方会
  • Invited
• [Presentation] 前庭障害モデルマウスを用いた前庭機能の解析 (2019)
  • Author(s): 押野玲奈、大神信孝、李香、He Tingchao、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] 生体サンプル中のヒ素レベルと聴力異常の関連 (2019)
  • Author(s): 大神信孝、李香、Xu Huadong、He Tingchao、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] 生体サンプル中の鉄レベルと聴力異常の相関解析 (2019)
  • Author(s): He Tingchao、大神信孝、李香、Xu Huadong、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] 可聴域の騒音ストレスによるラセン神経節への影響 (2019)
  • Author(s): 大神信孝、He Tingchao、Xu Huadong、押野玲奈、李香、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] 音楽に含まれる音成分と平衡感覚の関連 (2019)
  • Author(s): Xu Huadong、大神信孝、He Tingchao、李香、武田湖州恵、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] 延髄C1ニューロンを介する急性腎不全の軽減効果 (2019)
  • Author(s): 安部 力
  • Organizer: 第21回UTPシンポジウム
  • Invited
• [Presentation] 宇宙放射線研究におけるGatewayへの期待 (2019)
  • Author(s): 高橋昭久，日出間純，保田浩志
  • Organizer: 国際宇宙探査ワークショップ
• [Presentation] 低酸素環境下で発現上昇する新規低酸素誘導性分泌タンパク質HISP2はがん細胞の放射線抵抗性を誘導する (2019)
  • Author(s): 諏訪達也、小林稔、原田浩
  • Organizer: 第21回菅原・大西記念癌治療増感シンポジウム
• [Presentation] 放射線に対する強さ・弱さの個人差を決める遺伝子変化の探索 (2019)
  • Author(s): 宮本達雄、冨岡啓太、阿久津シルビア夏子、松浦伸也
  • Organizer: ふくしま県民公開大学
• [Presentation] 宇宙での微小重力環境におけるガンの進行 (2019)
  • Author(s): 高橋昭久
  • Organizer: 第33回宇宙環境利用シンポジウム
• [Presentation] 植物における宇宙での微小重力と模擬太陽光の複合影響研究 (2019)
  • Author(s): 日出間純，高橋昭久
  • Organizer: 第33回宇宙環境利用シンポジウム
• [Presentation] Increased chromosome aberrations in cells exposed simultaneously to simulated microgravity and radiation. (2019)
  • Author(s): Rhone JR, Beitman A, Ikeda H, Souda H, Yoshida Y, Held KD, Fujiwara K, Takahashi A, Saganti PB, Hada M.
  • Organizer: 2019 NASA Human Research Program Investigators' Workshop
  • Int'l Joint Research
• [Presentation] 分子腫瘍学・構造生物学・理論化学・臨床医学の融合によるがんの悪性進展制御因子に対するドラッグデザイン研究 (2019)
  • Author(s): 原田浩
  • Organizer: 日本医療研究開発機構（AMED) 平成30年度 創薬基盤推進研究事業公開シンポジウム-創薬のための基盤技術研究の推進と産学官連携の必要性-
  • Invited
• [Presentation] Relationship between endogenous ROS accumulation and mitochondria responses under low dose rate irradiation. (2019)
  • Author(s): Kobayashi J, Kawamura K, Qi F, Meng Q, Komatsu K.
  • Organizer: The 3rd International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
  • Int'l Joint Research
• [Presentation] Generation of NBS1 I171V knock-in mice using genome editing technology (2019)
  • Author(s): Tatsuo Miyamoto, Keita Tomioka, Silvia Natsuko Akutsu, Hiroshi Tauchi, Shinya Matsuura
  • Organizer: The 3rd International Symposium of the Next network-type Joint Usage / Research Center for Radiation Disaster Medical Science
  • Int'l Joint Research
• [Presentation] 宇宙での物質循環型植物工場 (2019)
  • Author(s): 北宅善昭
  • Organizer: 日本宇宙航空環境医学会の宇宙基地医学研究会
  • Invited
• [Presentation] Towards Decryption and Application of Tardigrades' resilience mechanisms. (2019)
  • Author(s): 國枝武和
  • Organizer: エンジニアリングネットワーク・ワークショップ
  • Invited
• [Presentation] 閉鎖生態系生命維持システムにおける有力栽培作物候補であるサツマイモ (2019)
  • Author(s): 北宅善昭
  • Organizer: 第33回 宇宙環境利用シンポジウム 一般セッション
• [Presentation] Gateway研究例紹介：生態工学の観点から (2019)
  • Author(s): 北宅善昭・桜井誠人
  • Organizer: 第33回 宇宙環境利用シンポジウム 深宇宙探査ゲートウェイ計画セッション
  • Invited
• [Presentation] Gateway研究例紹介：生態工学 (2019)
  • Author(s): 北宅善昭
  • Organizer: 将来月探査ワークショップ―HERACLES・Gatewayの活用―
  • Invited
• [Presentation] 宿主免疫による単純ヘルペスウイルスの認識機構とウイルスによる免疫回避機構 (2019)
  • Author(s): 川口 寧
  • Organizer: 第12回次世代アジュバント研究会
  • Invited
• [Presentation] ヒトの免疫から逃れる厄介なウイルスのお話し (2019)
  • Author(s): 川口 寧
  • Organizer: 北海道大学人獣共通感染症リサーチセンター市民公開講座「感染症の克服に向けて」
  • Invited
• [Presentation] 網羅的遺伝子発現解析結果に基づく膵β細胞障害メカニズムの解明. (2019)
  • Author(s): 西村 渉
  • Organizer: 岡山大学医歯学総合研究科大学院特別セミナー
  • Invited
• [Presentation] 国際宇宙ステーションにおける超高濃度CO2環境下での植物の生育改善 (2019)
  • Author(s): 古市卓也、松波志帆、加藤彩、中澤映李加、長尾由依、藤田博子
  • Organizer: 第60回日本植物生理学会
• [Presentation] オプトジェネティクス酸化ストレス誘導法による筋萎縮メカニズムの解明と治療薬探索Elucidation of muscle atrohpy mechanism by optogenetic oxidative stress induction method for screening of therapeutic drugs. (2018)
  • Author(s): Fuminori Sato
  • Organizer: 先進ゲノム解析研究推進プラットフォーム（先進ゲノム支援）拡大班会議
• [Presentation] Impacts of space flight and its ground models on the thymus (2018)
  • Author(s): Kenta Horie, Takao Seki, Nobuko Akiyama, Tamotsu Kato, , Hiroshi Ohno, Satoru Takahashi, and Taishin Akiyama
  • Organizer: 第47回日本免疫学会学術総会
• [Presentation] Dependency of thymic dendritic cell maturation on RANK and CD40 signaling (2018)
  • Author(s): Takao Seki, Kenta Horie, Nobuko Akiyama, Taishin Akiyama
  • Organizer: 第47回日本免疫学会学術総会
• [Presentation] Cell-Sized Aqueous/Aqueous Microdroplets: Compartments for Biomacromolecular Assembly Emerging through Micro-Phase Separation (2018)
  • Author(s): K. Tsumoto, H. Sakuta, M. Tomita, K. Takiguchi, K. Yoshikawa
  • Organizer: 12th International Symposium on Nanomedicine (ISNM2018)
  • Int'l Joint Research / Invited
• [Presentation] Monitoring of Calcium Ion Permeation Using Single GUVs Prepared with the Droplet Transfer Method (2018)
  • Author(s): Y. Uno, M. Nishigami, M. Tomita, K. Tsumoto
  • Organizer: 12th International Symposium on Nanomedicine (ISNM2018)
  • Int'l Joint Research
• [Presentation] Specific localization of living cells in water/water microdroplets toward the spontaneous generation of 3D cell-assembly: Experiments with red blood cells and NAMRU mouse mammary gland epithelial cells (2018)
  • Author(s): Y. Hoda, T. Fujimoto, K. Yoshikawa, K. Tsumoto
  • Organizer: 29th 2018 IEEE International Symposium on Micro-NanoMechatronics and Human Science (MHS 2018)
  • Int'l Joint Research
• [Presentation] Direct observation of chondrocytes under high hydrostatic pressure (2018)
  • Author(s): M. Morimatsu, A. Fujita, M. Nishiyama, K. Naruse
  • Organizer: ASCB 2018 米国細胞生物学会議
  • Int'l Joint Research
• [Presentation] Mechanical stress modulates the homeostasis of periodontal ligament (2018)
  • Author(s): Ayano Fujita, Masatoshi Morimatsu, Masayoshi Nishiyama, Shogo Takashiba, Keiji Naruse
  • Organizer: ASCB 2018 米国細胞生物学会議
  • Int'l Joint Research
• [Presentation] Study on gravity-dependent skeletal muscle maintenance mechanisms using Zebrafish, aquatic organisms (2018)
  • Author(s): Fuminori Sato, Minyong Choi, Zi Wang, Kiyomi Imamura, Terumi Horiuchi, Wu Quan, Ikumi Fujita, Satoko Uchida, Mitsuyasu Kato, Fumiaki Tanigaki, Akira Higashibata, Masafumi Muratani, Junya Kobayashi, Akihisa Takahashi, Sumio Sugano, Fumio Matsuzaki, Yutaka Suzuki, Koichi Kawakami, Atsuko Sehara-Fujisawa
  • Organizer: 2018 ASCB EMBO Meeting
  • Int'l Joint Research
• [Presentation] 新規運動耐性改善候補薬の標的因子探索 (2018)
  • Author(s): 矢島大聖、松本健、田中敦、小椋利彦
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] Self-Emergence of Cell-Like Structure of Actin and DNA in Cell-Sized Aqueous/Aqueous Micro Droplets (2018)
  • Author(s): Hiroki Sakuta, Kingo Takiguchi, Kanta Tsumoto, Kenichi Yoshikawa
  • Organizer: International Conference on Advances in Physics of Emergent orders in Fluctuations (APEF 2018)
  • Int'l Joint Research
• [Presentation] 微小重力環境下でのエピジェネティクスによる骨格筋制御因子の探索 (2018)
  • Author(s): 坪内鴻奈、岡田理沙、鈴木 陸、布施谷清香、林 卓杜、中村勇輝、久野朗広、村谷匡史、工藤 崇、高橋 智
  • Organizer: 第41回日本分子生物学会年会
  • Int'l Joint Research
• [Presentation] ユビキチンリガーゼCbl-bは無重力ストレス誘導性の酸化ストレスにより増大する (2018)
  • Author(s): 三木裕加里、内田貴之、木森有希、坂下禎宏、小松明生、真板綾子、内田実佑、藤岡大樹、小林剛、東谷篤志、石原直忠、東端晃、石岡憲昭、武田伸一、曽我部正博、二川健
  • Organizer: 第51回 日本栄養・食糧学会 中国・四国支部大会
• [Presentation] Cbl-b阻害ペプチド高含有米の除神経性筋萎縮改善作用の評価 (2018)
  • Author(s): 佐藤友紀、中尾玲子、赤間一仁、二川健
  • Organizer: 第51回 日本栄養・食糧学会 中国・四国支部大会
• [Presentation] Unloadingストレスに対する筋細胞の初期応：酸化ストレスの重要性 (2018)
  • Author(s): 二川健、内田貴之、中尾玲子、平坂勝也、真板宣夫、東谷篤志、小林剛、石原直忠、曽我部正博
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] 線虫の運動に対する放射線影響とその回復におけるオートファジーの関与 (2018)
  • Author(s): 渡辺 尚、森松 賢順、西山 雅祥、渡邉 賢、鍵 裕之、成瀬 恵治、東谷 篤志
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] 線虫を用いた筋ミトコンドリア研究 (2018)
  • Author(s): 東谷 篤志、小林 剛
  • Organizer: 第41回 日本分子生物科学会
• [Presentation] Unloadingストレスに対する筋細胞の初期応答: 酸化ストレスの重要性 (2018)
  • Author(s): 二川 健、内田 貴之、中尾 玲子、平坂 克也、真板 宣夫、東谷 篤志、小林 剛、石原 直忠、曽我部 正博
  • Organizer: 第41回 日本分子生物科学会
• [Presentation] ゼブラフィッシュ宇宙滞在実験から微小重力の骨格筋への影響とそのメカニズムを探るExploring the effect of microgravity on skeletal muscle and its mechanism from the space experiment using zebrafish (2018)
  • Author(s): 佐藤文規、Choi Minyong、王梓、今村聖実、堀内映美、呉 泉、藤田 生水、内田智子、加藤 充康、谷垣文章、東端 晃、村谷匡史、小林純也、高橋昭久、菅野純夫、松崎 文雄、鈴木穣、川上浩一、瀬原淳子
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] アクチン結合タンパク質Lima1を用いたFRET張力センサーの開発 (2018)
  • Author(s): 平野咲雪、山元孝佳、道上達男
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] 国際宇宙ステーションにおけるマウス実験 (2018)
  • Author(s): 高橋 智
  • Organizer: IETセミナー（東京）
  • Invited
• [Presentation] 静水圧負荷による軟骨細胞の圧力受容応答メカニズムの解明 (2018)
  • Author(s): 寺町一希, 森松賢順, 藤田彩乃, 西山雅祥, 成瀬恵治
  • Organizer: 第41回日本生体医工学会中国四国支部大会
• [Presentation] ゼブラフィッシュにおけるトランスポゾンを用いたゲノムワイド遺伝子トラップスクリーンと脳機能研究への応用 (2018)
  • Author(s): 川上浩一
  • Organizer: 第91回日本生化学会大会
  • Invited
• [Presentation] Response to physical force in C. elegans (2018)
  • Author(s): Atsushi Higashitani
  • Organizer: 日本生物物理学会第56回年会
  • Invited
• [Presentation] Spaceflight experiments using the nematode C. elegans (2018)
  • Author(s): Atsushi Higashitani
  • Organizer: The 15th Korea-Japan Joint Seminar on Space Environment Utilization Research
  • Int'l Joint Research / Invited
• [Presentation] 線虫の物理的力に対する応答 (2018)
  • Author(s): 東谷篤志
  • Organizer: 日本生物物理学会第56回年会
  • Invited
• [Presentation] A Mission Report on: Nematode Muscles Project in Spaceflight Experiment. (2018)
  • Author(s): Sudevan S, Hashizume T, Yano S, Kuriyama K, Momma K, Harada S, Umehara M, Higashibata A, Higashitani A.
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] 微小重力はドーパミンによる神経伝達に影響を及ぼすのか (2018)
  • Author(s): 橋爪藤子、梅原真澄、東端晃、東谷なほ子、東谷篤志
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] A Mission Report on: Epigenetics Project in C. elegans Spaceflight. (2018)
  • Author(s): Higashitani A, Hashizume T, Takiura M, Yano S, Kuriyama K, Umehara M, Higahibata A.
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] 骨格筋維持における重力の役割-ゼブラフィッシュの宇宙滞在から学ぶ事Roles of the gravity in the maintenance of skeletal muscle ? what we can learn from space stay of zebrafish (2018)
  • Author(s): 瀬原 淳子
  • Organizer: 第56回日本生物物理学会年会
  • Invited
• [Presentation] Space stay of zebrafish (2018)
  • Author(s): Atsuko Sehara
  • Organizer: The 15th Korea-Japan Joint Seminar on Space Environment Utilization Research
  • Int'l Joint Research / Invited
• [Presentation] 人工重力発生装置を用いたゼブラフィッシュ宇宙滞在実験 (2018)
  • Author(s): 佐藤文規, Choi Minyong, 王梓, 今村聖実, 堀内映美, 呉泉, 藤田生水, 内田智子, 加藤充康, 谷垣文章, 東端晃, 村谷匡史, 小林純也, 高橋昭久, 菅野純夫, 松崎文雄, 鈴木穣, 川上浩一, 瀬原淳子
  • Organizer: 宇宙生物科学会第32回大会
• [Presentation] Acute transcriptional control specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity (2018)
  • Author(s): Masahiro Chatani
  • Organizer: 15th Korea-Japan Joint Seminar on Space Environment Utilization Research
  • Int'l Joint Research / Invited
• [Presentation] Effects of gravity change on medaka fish hard tissues (2018)
  • Author(s): Masahiro Chatani, Aiko Mitsuhashi, Yusuke Dodo, Yuki Azetsu, Nobuhiro Sakai, Akira Kudo, Masamichi Takami
  • Organizer: 29th Australian and New Zealand Bone and Mineral Society (ANZBMS) ANNUAL SCIENTIFIC MEETING
  • Int'l Joint Research
• [Presentation] Toward the Elucidation of Cell Gravi-Sensing in Space. (2018)
  • Author(s): Masahiro SOKABE, Takeshi Kobayashi, Takeshi Nikawa, Keiji Naruse, Akira Higashibata
  • Organizer: the 15th Korea-Japan Joint Seminar on Space Environment Utilization Research
  • Int'l Joint Research
• [Presentation] 間葉系幹細胞の重力感知における機械刺激受容チャンネルTRPV4を介したシグナル伝達経路の役割 (2018)
  • Author(s): 加藤信靖, 田中瑞奈, 曽我部正博, 小林 剛
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] 生細胞の細胞膜上での機械刺激受容チャンネルTRPV4の動態の解析 (2018)
  • Author(s): 堀池由朗, 田中瑞奈, 加藤信靖, 成瀬恵治, 曽我部正博, 小林 剛
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] Giant vesicles rapidly prepared and purified using a reverse-phase/centrifugation method (2018)
  • Author(s): Kanta Tsumoto, Kohei Nakano, Yuki Hayashi, Masahiro Tomita
  • Organizer: 第56回日本生物物理学会年会
• [Presentation] Spatial Cooperation between DNA and Actin in Micro-Confinement Generated throughSpontaneous Phase Segregation (2018)
  • Author(s): Hiroki Sakuta, Naoki Nakatani, Masahito Hayashi, Kingo Takiguchi, Kanta Tsumoto,Kenichi Yoshikawa
  • Organizer: 第56回日本生物物理学会年会
• [Presentation] 界面通過法により作製したGUVによるカルシウムイオン膜透過性評価 (2018)
  • Author(s): 宇野勇気，西上美佐子，冨田昌弘，湊元幹太
  • Organizer: 第91回日本生化学会大会
• [Presentation] Regulatory mechanism of root hydrotropism for water acquisition in arid environment (2018)
  • Author(s): Hideyuki Takahashi
  • Organizer: International Symposium on Plant Survival Strategies in Extreme Environment at 32nd Annual Meeting of the Japanese Society for Biological Sciences in Space
  • Int'l Joint Research / Invited
• [Presentation] HSP90とNPH3がシロイヌナズナの根の水分屈性をMIZ1と協調的に制御する可能性 (2018)
  • Author(s): 山崎 誠和、小泉 日輪、小林 啓恵、藤井 伸治、宮沢 豊、高橋 大輔、河村 幸男、上村 松生、高橋 秀幸
  • Organizer: 日本植物学会第82回大会
• [Presentation] SnRK2sによるリン酸化に着目したABA-MIZ1シグナリング経路の解明 (2018)
  • Author(s): 里 和希, 小林 啓恵, 藤井 伸治, Dietrich Daniela, Bennett Malcolm, 高橋 秀幸
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] シロイヌナズナの根の水分屈性にMIZ1と共にHSP90とNPH3が機能する (2018)
  • Author(s): 山崎 誠和、小泉 日輪、小林 啓恵、藤井 伸治、宮沢 豊、高橋 大輔、河村 幸男、上村 松生、高橋 秀幸
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] キュウリの芽生えの発芽時の重力条件により発現が変動する遺伝子の探索 (2018)
  • Author(s): 藤井伸治、宮林彩智子、小林啓恵、山崎千秋、宮沢豊、鎌田源司、笠原春夫、長田郁子、嶋津徹、伏島康男、東端晃、山崎丘、石岡憲昭、高橋秀幸
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] 無重力による廃用性筋萎縮におけるROSの重要性 (2018)
  • Author(s): 木森有希
  • Organizer: 第19回運動器科学研究会
• [Presentation] Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells (2018)
  • Author(s): Takayuki Uchida
  • Organizer: 日本宇宙生物科学会第32回大会・第15回宇宙環境利用研究日韓合同セミナー合同国際大会
  • Int'l Joint Research
• [Presentation] 酸化ストレスはラットL6細胞におけるユビキチンリガーゼCbl-bの発現を増大する (2018)
  • Author(s): 三木裕加里、内田貴之、木森有希、坂下禎宏、小松明生、真板綾子、中尾玲子、内田実佑、藤岡大樹、小林剛、東谷篤志、石原直忠、武田伸一、曽我部正博、東端晃、石岡憲昭、二川健
  • Organizer: 日本宇宙生物科学会第32回大会・第15回宇宙環境利用研究日韓合同セミナー合同国際大会
  • Int'l Joint Research
• [Presentation] 廃用性筋萎縮を抑制するユビキチンリガーゼCbl-bの低分子阻害剤の開発 (2018)
  • Author(s): 小松明生、内田貴之、北畑香菜子、真板綾子、中尾玲子、瀬川圭、武田伸一、二川健
  • Organizer: 日本筋学会第4回学術集会
• [Presentation] グーデア科胎生魚において母親から胎仔に供給される栄養分の実態は何か？ (2018)
  • Author(s): 飯田 敦夫
  • Organizer: 第４回ユニークな少数派実験動物を扱う若手が最先端アプローチを勉強する会
• [Presentation] Viviparous telelost: Exploration of the maternal-fetal nutritional transfer in a Goodeidae species Xenotoca eiseni (2018)
  • Author(s): ATSUO IIDA
  • Organizer: 第24回小型魚類研究会
• [Presentation] The ectodomain shedding of NRG1 underlies spatial and temporal regulation of synaptogenesis and myelination of developing motor neurons (2018)
  • Author(s): F. Sato, M. Tabuchi, A. Kamezaki, A. Asakawa, K. Kawakami, A. Sehara-Fujisawa
  • Organizer: 11th meeting of the Zebrafish Disease Models Society (ZDM11)
  • Int'l Joint Research
• [Presentation] 微重力環境下におけるゼブラフィッシュの行動解析及び、遺伝子発現変動解析 (2018)
  • Author(s): Choi Minyong, F Sato and A Sehara
  • Organizer: 平成30年度「宇宙に生きる」若手夏合宿
• [Presentation] 宇宙実験から得た抗筋萎縮栄養法 (2018)
  • Author(s): 二川健
  • Organizer: 第6回日本腎栄養代謝研究会学術集会・総会
• [Presentation] Transcriptome analysis of gravitational effects on muscles of mice (2018)
  • Author(s): 高橋 智
  • Organizer: ISS R&D Conference 2018
  • Int'l Joint Research
• [Presentation] Japan’s first rodent mission using JAXA Mouse Habitat Unit (MHU-1) (2018)
  • Author(s): 高橋 智
  • Organizer: NASA/JAXA Joint Workshop at ISS R&D Conference 2018
  • Int'l Joint Research
• [Presentation] 重力が歯と骨の恒常性に及ぼす作用－メダカを用いた加重力実験 (2018)
  • Author(s): 茶谷 昌宏, 三橋 あい子, 畔津 佑季, 坂井 信裕, 工藤 明, 髙見 正道
  • Organizer: 第36回骨代謝学会学術集会
• [Presentation] Comparison of the regulatory mechanisms for gravitropism and hydrotropism in seedling roots (2018)
  • Author(s): Hideyuki Takahashi
  • Organizer: Cimmission on Space Research (COSPAR) 42nd Assembly
  • Int'l Joint Research
• [Presentation] SnRK2sによるリン酸化シグナルに着目したABA-MIZ1シグナリング経路の解明 (2018)
  • Author(s): 里 和希
  • Organizer: 「宇宙に生きる」夏の学校
• [Presentation] 植物の根が水分勾配を感受するための機能分子の探索 (2018)
  • Author(s): 高橋 弘紀
  • Organizer: 「宇宙に生きる」夏の学校
• [Presentation] 有膜と無膜の区画、形成と機能 (2018)
  • Author(s): 湊元幹太
  • Organizer: 「分子ロボティクス研究会」2018年7月 定例研究会
  • Invited
• [Presentation] Genetic analysis of anxiety-related behavior in zebrafish (2018)
  • Author(s): Kotani, Yuri, and Kawakami, Koichi
  • Organizer: 第４１回日本神経科学大会
  • Int'l Joint Research
• [Presentation] Genetic analysis of anxiety-related behavior in zebrafish (2018)
  • Author(s): Kotani, Yuri, and Kawakami, Koichi
  • Organizer: 11th Annual Zebrafish Disease Models Conference
  • Int'l Joint Research
• [Presentation] 重力が歯と骨の恒常性に及ぼす作用－メダカを用いた加重力実験 (2018)
  • Author(s): 茶谷 昌宏, 三橋 あい子, 畔津 佑季, 坂井 信裕, 工藤 明, 髙見 正道
  • Organizer: 第347回昭和大学学士会例会
• [Presentation] Roles of a transcription factor 19A in the osteoblast development of sternum (2018)
  • Author(s): Mao Kuriki, Fuminori Sato, Kenta Sumiyama, Koichi Kawakami, Atsuko Sehara-Fujisawa
  • Organizer: Joint Annual Meeting of JSDB 51st and JSCB 70th （日本細胞生物学会・日本発生生物学会合同大会）
• [Presentation] Metabolic control of skeletal muscle regeneration (2018)
  • Author(s): Shimpei Hori, Fuminori Sato, Atsuko Sehara-Fujisawa
  • Organizer: Joint Annual Meeting of JSDB 51st and JSCB 70th （日本細胞生物学会・日本発生生物学会合同大会）
• [Presentation] 動物が重力を感じるしくみと反応?ヒトは宇宙に長くいるとどうなるのか? (2018)
  • Author(s): 瀬原淳子
  • Organizer: 大隅基礎科学創成財団主催 小中高生と最先端研究者とのふれ合いの集い
  • Invited
• [Presentation] The ectodomein shedding of NRG1 underlies spatial and temporal regulation of synaptogenesis and myelination of developing motor neurons (2018)
  • Author(s): F. Sato, M. Tabuchi, A. Kamezaki, A. Asakawa, K. Kawakami, A. Sehara-Fujisawa
  • Organizer: 22nd Biennial Meeting of the International Society of Developmental Neuroscience
  • Int'l Joint Research / Invited
• [Presentation] Cell-Sized Lipid Vesicles as Microcompartments for Mimicking Cells: Rapid Prepartion and Installation of Recombinant Proteins (2018)
  • Author(s): Kanta Tsumoto, Kohei Nakanishi, Yuki Hayashi, Masahiro Tomita
  • Organizer: The 6th Japan-China Symposimu on Nanomedicine
  • Int'l Joint Research / Invited
• [Presentation] 逆相遠心法による細胞サイズベシクル調製と膜ミクロドメイン形成 (2018)
  • Author(s): 仲野耕平，林佑紀，冨田昌弘，湊元幹太
  • Organizer: 第82回日本生化学会中部支部例会・シンポジウム
• [Presentation] Spontaneous Specific Localization of Actin and DNA in Cell-sized Water/Water Micro Droplet (2018)
  • Author(s): Hiroki Sakuta, Kingo Takiguchi, Kanta Tsumoto, Kenichi Yoshikawa
  • Organizer: International Symposium on “Artificial Cell Reactor Science and Technology”
  • Int'l Joint Research
• [Presentation] Central mechanism of thermoregulation via the vestibular system in mice (2018)
  • Author(s): Chikara Abe, Yusuke Yamaoka, Hironobu Morita
  • Organizer: Society for Neuroscience 2018
  • Int'l Joint Research
• [Presentation] Peripheral mechanism for thermoregulation via the vestibular system in mice (2018)
  • Author(s): Yusuke Yamaoka, Chikara Abe, Hironobu Morita
  • Organizer: Society for Neuroscience 2018
  • Int'l Joint Research
• [Presentation] 前庭神経核ニューロンの可塑による交感神経反射の低下 (2018)
  • Author(s): 安部 力，山岡 優佑，森田 啓之
  • Organizer: 第６５回中部日本生理学会
• [Presentation] OsteocrinはCNPシグナルを制御して皮質骨の形成に関わる (2018)
  • Author(s): 高野晴子
  • Organizer: Skeletal Science Retreat 2018（日本骨代謝学会主催 骨代謝スクール)
• [Presentation] 睡眠導入剤がヒトの脳循環動態に及ぼす影響 (2018)
  • Author(s): 田子 智晴、小川 洋二郎、小西 透、加藤 智一、倉住 拓弥、柳田 亮、岩﨑 賢一
  • Organizer: 第64回日本宇宙航空環境医学会大会
• [Presentation] Exercise can maintain brain function by fNIRS using VFT in confined environment like ISS in Japan - Single case experimental ABA design - (2018)
  • Author(s): Shin-ichiro Sasahara, Yuichi Oi, Yasuhito Hirai, Shotaro Doki, Yuh Ohtaki, Daisuke Hori, Christina-Sylvia Andrea, Tamaki Saito, Ichiyo Matsuzaki
  • Organizer: International Astronautical Congress 2018 (IAC2018)
  • Int'l Joint Research
• [Presentation] AVP神経特異的小胞GABAトランスポーター遺伝子欠損マウスにおける中枢概日時計の解析 (2018)
  • Author(s): 前島隆司、長谷川恵美、津野祐輔、三枝理博
  • Organizer: 第25回日本時間生物学会学術大会
• [Presentation] 宇宙フライトマウス前庭系のエピゲノム解析から見た重力環境応答の可塑性 (2018)
  • Author(s): 村谷匡史、安部力、藤田晋一郎、山岡優佑、工藤崇、高橋智、森田啓之
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] 閉鎖空間の低周波騒音曝露による内耳のストレス関連分子の発現 (2018)
  • Author(s): 李香, 大神信孝, 押野玲奈, 二宮裕将, 加藤昌志
  • Organizer: 日本宇宙生物科学会第 32 回大会
• [Presentation] 運動が引き起こす骨格筋エピジェネティクスと適応限界の仕組み (2018)
  • Author(s): 河野 史倫
  • Organizer: 第4回日本筋学会
  • Invited
• [Presentation] 運動が引き起こす骨格筋エピジェネティクスと適応限界の仕組み (2018)
  • Author(s): 河野 史倫
  • Organizer: 第4回日本筋学会学術集会
  • Invited
• [Presentation] 前庭系が体温調節に与える影響：末梢のメカニズム (2018)
  • Author(s): 山岡優佑
  • Organizer: 第28回日本病態生理学会大会
• [Presentation] 前庭系が体温調節に与える影響：中枢のメカニズム (2018)
  • Author(s): 安部 力
  • Organizer: 第28回日本病態生理学会大会
• [Presentation] Assessing confinement environment stress using fNIRS (2018)
  • Author(s): Christina-Sylvia Andrea, 大井雄一, 平井康仁, 道喜将太郎, 大滝 優, 堀 大介, 高橋 司, 笹原信一朗, 斎藤 環, 松崎 一葉
  • Organizer: International society of Neurobiology & Psychopharmacology
  • Int'l Joint Research
• [Presentation] 閉鎖環境における ストレス対処能力と運動の関連 (2018)
  • Author(s): 髙橋司、道喜将太郎、白木渚、Christina-Sylvia Andrea、大滝優、堀大介、大井雄一、笹原信一朗、松崎一葉
  • Organizer: 「宇宙に生きる」若手の会
• [Presentation] 閉鎖環境での心理的ストレス検出の 光トポグラフィー利用の新しい可能性 (2018)
  • Author(s): 道喜将太郎、笹原信一朗、髙橋司、白木渚、Christina-Sylvia Andrea、大滝優、堀大介、大井雄一、松崎一葉
  • Organizer: 「宇宙に生きる」若手の会
• [Presentation] Osteocrinは長管骨形成を制御する骨膜ホルモンである (2018)
  • Author(s): 高野晴子
  • Organizer: 第36回日本骨代謝学会学術集会
• [Presentation] C1 neurons mediate a stress-induced protection of renal ischemia/reperfusion injury (2018)
  • Author(s): 安部 力
  • Organizer: 第41回日本神経科学大会
  • Invited
• [Presentation] Effects of Hypergravity on the Gene Expression of the Hypothalamic Feedingrelated Neuropeptides in Mice Via Vestibular Inputs (2018)
  • Author(s): Yoichi Ueta, Satomi Sonoda, Mitsuhiro Yoshimura, Chikara Abe, Hironobu Morita, Haruki Nishimura, Kazuaki Nishimura, kentaro Tanaka, Hiromichi Ueno, Ysuhito Motojima, Reiko Saito, Takashi Maruyama
  • Organizer: ICN2018
  • Int'l Joint Research
• [Presentation] 中枢概日時計におけるバソプレシンニューロンの機能 (2018)
  • Author(s): 三枝理博
  • Organizer: 第４３回日本睡眠学会定期学術集会
• [Presentation] Genetic dissection of neural mechanisms underlying the central circadian pacemaker (2018)
  • Author(s): 三枝理博
  • Organizer: Sapporo Symposium on Biological Rhythm in 2018
  • Int'l Joint Research / Invited
• [Presentation] Neural mechanisms underlying the central circadian pacemaker of the SCN (2018)
  • Author(s): 三枝理博
  • Organizer: 第４１回日本神経科学大会
• [Presentation] マンガンの飲水曝露による聴覚系への影響 (2018)
  • Author(s): 大神信孝、李香、押野玲奈、加藤昌志
  • Organizer: 第29回日本微量元素学会学術集会
• [Presentation] ヒトのツメに蓄積するマンガンレベルと聴力の関連 (2018)
  • Author(s): He Tingchao、大神信孝、李香、加藤昌志
  • Organizer: 第29回日本微量元素学会学術集会
• [Presentation] 実験研究と疫学研究によるヒ素曝露の難聴リスクの解析 (2018)
  • Author(s): 李香、大神信孝、押野玲奈、加藤昌志
  • Organizer: 第29回日本微量元素学会学術集会
• [Presentation] Effects of long-term noisy vestibular stimulation on body balance in bilateral vestibulopathy. (2018)
  • Author(s): Iwasaki S, Fujimoto C, Egami N, Kawahara T, Uemura Y, Yamamoto Y, Yamasoba T.
  • Organizer: XXX Barany Society Meeting
  • Int'l Joint Research
• [Presentation] ノイズ前庭電気刺激による前庭障害患者の体平衡機能改善機器の開発 (2018)
  • Author(s): 岩﨑真一
  • Organizer: 第119回 日本耳鼻咽喉科学会総会
  • Invited
• [Presentation] The effects of mild intravascular dehydration on intracranial pressure and cerebral circulation (2018)
  • Author(s): Takuya Kurazumi, Yojiro Ogawa, Chiharu Takko, Tomokazu Kato, Toru Konishi, Ken-ichi Iwasaki
  • Organizer: 8th Meeting of the Cerebral Autoregulation Network (CARNet)
  • Int'l Joint Research
• [Presentation] Deference in dietary fatty acid composition changes energy metabolism, biological rhythm and sleep. (2018)
  • Author(s): Park I, Oosumi H, Zhang S, Ishihara A, Tanaka Y, Yajima K, Iwayama K, Omi N, Tokuyama K, Satoh M
  • Organizer: The 13th Congress Of The International Society For The Study Of Fatty Acids And Lipids.
  • Int'l Joint Research
• [Presentation] 低周波騒音曝露の健康リスクを評価する実験研究 (2018)
  • Author(s): 李香、大神信孝、押野玲奈、二宮裕将、加藤昌志
  • Organizer: 第91回日本産業衛生学会術総会
• [Presentation] PDMSマイクロ流路チップを用いたDNA損傷評価システムの開発 (2018)
  • Author(s): 高橋 健太, 田村 隆大, 鈴木 孝明, 中村 麻子
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] ゲノム編集技術を用いたNBS1 I171Vノックインマウスの作製 (2018)
  • Author(s): 宮本達雄、Silvia Natsuko Akutsu、田内広、松浦伸也
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] Experimental strategies for the chromosome therapy in Down Syndrome cell (2018)
  • Author(s): Silvia Natsuko Akutsu, Tatsuo Miyamoto, Hirofumi Ohashi, Shinya Matsuura
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] ゲノム編集技術を用いたナイミーヘン症候群原因遺伝子NBS1 I171V多型ノックインマウスの作製 (2018)
  • Author(s): 宮本達雄、冨岡啓太、阿久津シルビア夏子、山本卓、田内広、松浦伸也
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] ゲノム不安定性が引き起こす加齢性皮膚疾患の分子病態解析 (2018)
  • Author(s): 久保亮治、藤田春美、佐々木貴史、中林一彦、宮本達雄、小崎健次郎
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] 霊長類細胞を用いた DNA 損傷応答の多様性の解析 (2018)
  • Author(s): QI FEI、河村 香寿美、今井 啓雄、平井 啓久、小林 純也
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] 日本人 AT-LD 患者におけるMRE11 変異部位と DNA 損傷応答異常との 関係 (2018)
  • Author(s): 河村 香寿美、Qi Fei、加藤 竹雄、松浦 伸也、小松 賢志、小林 純也
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] 低線量率照射による DNA 損傷と酸化ストレス応答因子 (2018)
  • Author(s): 孟 慶梅、QI FEI、河村 香寿美、小林 純也
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] 植物の核・ミトコンドリア・葉緑体DNA上のCPD蓄積とUVB感受性ワークショップ：高次の紫外線障害における修復機構 (2018)
  • Author(s): Gonul Dundar、原遵、小松千春、小川裕雅、髙橋有希、寺西美佳、日出間純
  • Organizer: 日本放射線影響学会第61回大会
  • Invited
• [Presentation] 低酸素/HIF-1バイオロジーを基軸とする放射線腫瘍生物学研究-放生研の研究プラットフォームを交えて- (2018)
  • Author(s): 原田浩
  • Organizer: 第61回日本放射線影響学会
  • Invited
• [Presentation] HIF-1 induces HMHA1 expression at transcription initiation and mRNA stability levels under hypoxic conditions (2018)
  • Author(s): Tamao Kameda, Minoru Kobayashi, Akiyo Morinibu, Hiroshi Harada
  • Organizer: The 34th International Symposium for Radiation Biology Center, Kyoto University
  • Int'l Joint Research
• [Presentation] A novel hypoxia-inducible secretory protein, HISP-2, causes radioresistance of cancer cells under hypoxic conditions in an autocrine manner (2018)
  • Author(s): Tatsuya Suwa, Minoru Kobayashi, Hiroshi Harada
  • Organizer: The 34th International Symposium for Radiation Biology Center, Kyoto University
  • Int'l Joint Research
• [Presentation] Accumulation of p53 protein under hypoxia depends on a ribosomal protein L11 (RPL11)-dependent nucleolar stress signaling (2018)
  • Author(s): Ayako Nagao, Minoru Kobayashi, Kouichi Kawahara, Tatsuhiko Furukawa, Hiroshi Harada
  • Organizer: The 34th International Symposium for Radiation Biology Center, Kyoto University
  • Int'l Joint Research
• [Presentation] A Circadian Clock Gene, PER2, Activates HIF-1 as an Effector Molecule for Recruitment of HIF-1α to Promoter Regions of Its Downstream Genes (2018)
  • Author(s): Minoru Kobayashi, Akiyo Morinibu, Sho Koyasu, Yoko Goto, Masahiro Hiraoka, Hiroshi Harada
  • Organizer: The 34th International Symposium for Radiation Biology Center, Kyoto University
  • Int'l Joint Research
• [Presentation] HPF-4: the novel gene that links p53-deficiency to HIF-1 and induces malignant phenotypes of cancer cells (2018)
  • Author(s): Sho Koyasu, Akiyo Morinibu, Toshi Menju, Shoichiro Horita, Ester M Hammond, Hiroshi Ishikita, Hiroshi Harada
  • Organizer: The 34th International Symposium for Radiation Biology Center, Kyoto University
  • Int'l Joint Research
• [Presentation] p53変異型腫瘍の悪性進展を抑制するPPI阻害剤創製に向けた試み (2018)
  • Author(s): 子安 翔、斉藤 圭亮、堀田 彰一朗、石北 央、原田 浩
  • Organizer: 第1回モダリティ創薬デザイン研究会シンポジウム
  • Invited
• [Presentation] ヒト骨髄由来幹細胞を用いた中性子線被ばく影響評価と防護剤効果 (2018)
  • Author(s): 中島徹夫、二宮康晴、丸山耕一、小川原亮、須田充、根井充
  • Organizer: 日本放射線影響学会
• [Presentation] 線質の異なる放射線誘発マウス肺がんの病理組織的評価 (2018)
  • Author(s): 鈴木健之、山崎隼輔、岩田健一、山田裕、森岡孝満、臺野和広、甘崎佳子、小川真里、島田義也、柿沼志津子
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] 鉄イオン線照射後のマウスに発生するリンパ系腫瘍の解析 (2018)
  • Author(s): 小久保結未、森岡孝満、臺野和広、金小海、石川敦子、橘拓孝、小川真里、藤田美鈴、柿沼志津子、田代聡
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] シンポジウム：皮膚マイクロバイオーム研究は何を明らかにしたか。ー健康、疾病、そして宇宙ー (2018)
  • Author(s): 杉田隆
  • Organizer: 日本放線菌学会 第63回学術企画講演会
• [Presentation] Detecting Environmental Fungi with the Loop-mediated Isothermal Amplification Method (2018)
  • Author(s): Takashi Yamazaki, Takako Nakayama, Ayaka Yo, Kazuya Tone, Mohamed Mahdi Alshahni, Ryuichi Fujisaki, Koichi Makimura
  • Organizer: 2018 International Meeting of the Federation of Korean Microbiological Societies
  • Int'l Joint Research
• [Presentation] ヒト培養細胞におけるゲノム編集を用いた遺伝性小頭症の病因・病態解明 (2018)
  • Author(s): 宮本達雄、Silvia Natsuko Akutsu、松浦伸也
  • Organizer: 日本人類遺伝学会 第63回大会
  • Invited
• [Presentation] 腫瘍低酸素に係る基礎研究と臨床応用 (2018)
  • Author(s): 原田浩
  • Organizer: 第31回日本放射線腫瘍学会
  • Invited
• [Presentation] システイン反応性Nrf2誘導剤に対する応答を欠失したKeap1変異体の創出 (2018)
  • Author(s): 鈴木隆史、村松亜紀、斎藤良太, 磯達朗、山本雅之
  • Organizer: 第91回日本生化学大会
• [Presentation] Keap1酸化ストレスセンサーの機能解析 (2018)
  • Author(s): 村松亜紀、鈴木隆史、斎藤良太, 磯達朗、須田博美、守田匡伸、山本雅之
  • Organizer: 第91回日本生化学大会
• [Presentation] 量研高崎研のマイクロビーム生物照射技術を用いた生物局部照射効果研究 (2018)
  • Author(s): 舟山知夫
  • Organizer: 第32回宇宙生物科学会大会
  • Int'l Joint Research / Invited
• [Presentation] 高LET放射線によって生じたマウス肺がんの病理組織学的評価 (2018)
  • Author(s): 鈴木健之、山崎隼輔、岩田健一、森岡孝満、臺野和広、甘崎佳子、小川真里、山田裕、島田義也、柿沼志津子
  • Organizer: 日本宇宙生物科学会第32回大会
  • Int'l Joint Research
• [Presentation] 重粒子線・中性子線施設を用いた宇宙放射線影響研究 (2018)
  • Author(s): 柿沼志津子, 鶴岡千鶴, 尚 奕, 甘崎佳子, 今岡達彦, 西村まゆみ, 島田義也
  • Organizer: 日本宇宙生物科学会第32回大会
  • Int'l Joint Research / Invited
• [Presentation] 尾部懸垂マウスにおける免疫系器官の萎縮と腫瘍の悪性化 (2018)
  • Author(s): 脇畑 庄人，馬 立秋，大平 充宣，神戸 崚輔，吉田 由香里，高橋 昭久
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] 宇宙放射線研究のための今後の展望 (2018)
  • Author(s): 高橋 昭久
  • Organizer: 日本宇宙生物科学会第32回大会
• [Presentation] Developing neurons are sensitive to 0.5 Gy and 1 Gy of X-irradiation which also causes a decrease in the number of un-irradiated neurons in co-culture (2018)
  • Author(s): Anggraeini Puspitasari, Hiroyuki Yamazaki, Akihisa Takahashi, Tomoaki Shirao, Takashi Nakano, Kathryn D Held
  • Organizer: RRS2018
  • Int'l Joint Research
• [Presentation] 微小重力環境は、植物の紫外線障害・修復・応答に影響を及ぼすのか？ (2018)
  • Author(s): 日出間純
  • Organizer: 日本植物学会第82回大会
  • Invited
• [Presentation] Combined effects of microgravity and UVB radiation on plant. (2018)
  • Author(s): Jun Hidema, Akihisa Takahashi
  • Organizer: 第56回日本生物物理学会年会
  • Invited
• [Presentation] Effects of microgravity on UVB-induced damage of plant (2018)
  • Author(s): Jun Hidema
  • Organizer: 日本宇宙生物科学会第32回大会・第15回宇宙環境利用研究日韓合同セミナー合同国際大会
  • Int'l Joint Research / Invited
• [Presentation] PDMSマイクロ流路チップを用いたDNA損傷評価システムの開発 (2018)
  • Author(s): 高橋 健太, 田村 隆大, 鈴木 孝明, 中村 麻子
  • Organizer: 宇宙生物科学会第32回大会
• [Presentation] 一塩基編集技術を用いた遺伝性小頭症の病因・病態解明 (2018)
  • Author(s): 宮本達雄, Silvia Natsuko Akutsu, 松浦伸也
  • Organizer: 日本生化学第91回大会
  • Invited
• [Presentation] p53機能欠失下で作用する新規のHIF-1活性化因子HPF-4について (2018)
  • Author(s): 子安翔、原田浩
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating Shh. (2018)
  • Author(s): 小林稔、片桐幸大、原田浩
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] 臓器間のDNA損傷耐用能の違いから迫る”宇宙放射線克服に向けた基盤構築” (2018)
  • Author(s): 原田浩、小林稔、鶴岡千鶴、柿沼志津子
  • Organizer: 日本宇宙生物科学会第32回大会
  • Invited
• [Presentation] HIF-1 and radioresistance (2018)
  • Author(s): 原田浩
  • Organizer: 東北大学大学院薬学研究科遺伝子制御薬学分野セミナー
  • Invited
• [Presentation] 重粒子線・中性子線施設を用いた宇宙放射線影響研究 (2018)
  • Author(s): 柿沼志津子, 鶴岡千鶴, 尚 奕, 甘崎佳子, 今岡達彦, 西村まゆみ, 島田義也
  • Organizer: 日本宇宙生物科学会
  • Invited
• [Presentation] CPD光回復酵素の葉緑体局在と発現機構の植物種間差 (2018)
  • Author(s): 原遵、小松千春、小川裕雅、髙橋有希、寺西美佳、日出間純
  • Organizer: 第20回光生物学協会年会
• [Presentation] Estimation of carcinogenic risk after exposure to space radiation by pathological and genomic analyses (2018)
  • Author(s): Shizuko Kakinuma, Jin Xiaohai, Hirotaka Tachibana, Takamitsu Morioka, Kazuhiro Daino, Chizuru Tsuruoka, Yi Shang, Yoshiko Amasaki, Yoshiya Shimada
  • Organizer: The 44th European Radiation Research Congress
  • Int'l Joint Research
• [Presentation] Radioresistance of cells under hypoxia (2018)
  • Author(s): Hiroshi Harada
  • Organizer: 2nd Hokkaido Summer Institute
  • Int'l Joint Research / Invited
• [Presentation] FISH analysis of chromosomal aberrations induced by accelerated heavy iron particles in mouse splenocytes (2018)
  • Author(s): Takanori Katsube, Bing Wang, Kaoru Tanaka, Yasuharu Ninomiya, Hirokazu Hirakawa, Cuihua Liu, Kouichi Maruyama, Guillaume Varès, Tetsuo Nakajima, Akira Fujimori, Mitsuru Nenoi.
  • Organizer: The 42nd COSPAR Scientific Assembly
  • Int'l Joint Research
• [Presentation] Induction of genotoxicity by accelerated heavy iron particles in the hematopoietic system in mice (2018)
  • Author(s): Bing Wang, Kaoru Tanaka, Takanori Katsube, Yasuharu Ninomiya, Hirokazu Hirakawa, Cuihua Liu, Kouichi Maruyama, Guillaume Vares, Tetsuo Nakajima, Akira Fujimori, Mitsuru Nenoi.
  • Organizer: The 42nd COSPAR Scientific Assembly
  • Int'l Joint Research
• [Presentation] Exprimental trials for the chromosome aneuploidy correction in Down syndrome cell lines (2018)
  • Author(s): Silvia Natsuko Akutsu, Tatsuo Miyamoto, Hrofumi Ohashi, Shinya Matsuura
  • Organizer: 第43回中国地区放射線影響研究会
• [Presentation] Bioburden and Environmental Microbiome in a Pharmaceutical Manufacturing Facility (2018)
  • Author(s): Mako Kawai, Tomoaki Ichijo, Takashi Sugita, Masao Nasu
  • Organizer: Gordon Research Conference on Microbiology of the Built Environment
• [Presentation] 皮膚マイクロバイオームの解析とその制御戦略 (2018)
  • Author(s): 杉田隆
  • Organizer: 第48回北陸真菌懇談会
  • Invited
• [Presentation] Comprehensive Analysis of the microbiome (2018)
  • Author(s): Takashi Sugita
  • Organizer: 20th Congress of the International Society for Human and Animal Mycology
  • Int'l Joint Research / Invited
• [Presentation] The synergistic effect of simulated microgravity and charged particle radiation on gene expression in human fibroblasts (2018)
  • Author(s): Hiroko Ikeda, Masafumi Muratani, Anggraeini Puspitasari, Kathryn D. Held, Jun Hidema, Yukari Yoshida, Akihisa Takahashi
  • Organizer: COSPAR2018
  • Int'l Joint Research
• [Presentation] Microbial Monitoring in A Pharmaceutical Manufacturing Facility: A Space Habitat Analogue (2018)
  • Author(s): Tomoaki Ichijo, Mako Kawai, Yuji Takahashi, Takashi Sugita, Masao Nasu
  • Organizer: ASM Microbe 2018
• [Presentation] ジアリルジスルフィドの放射線防護効果と宇宙環境での利用について (2018)
  • Author(s): 中島 徹夫, Guillaume Vares, 二宮 康晴, 王 冰, 勝部 孝則, 田中 薫, 劉 翠華, 平川 博一, 丸山 耕一, 藤森 亮, 根井 充
  • Organizer: 第７２回日本栄養・食糧学会大会
• [Presentation] 皮膚マイクロバイオームとしてのマラセチア (2018)
  • Author(s): 杉田隆
  • Organizer: 第117回日本皮膚科学会総会
  • Invited
• [Presentation] クマムシ固有の分泌型熱可溶性タンパク質SAHSの翻訳後修飾の解析Analysis of post-translational modifications of tardigrade-unique secretory heat soluble protein SAHS (2018)
  • Author(s): 田中彬寛、山口志保、國枝武和
  • Organizer: 第19回極限環境生物学会
• [Presentation] 乾燥耐性をもたないクマムシIsohypsibius myropsの放射線耐性 (2018)
  • Author(s): 西郷 永希子, 伊藤 麻紀子, 佐藤 勝也,國枝 武和
  • Organizer: 第19回極限環境生物学会
• [Presentation] 高い放射線耐性を持つクマムシに固有なDNA防護タンパク質DsupのDNA保護メカニズムの解析Analysis of DNA-protection mechanism of a novel DNA-protection protein, Dsup, unique to a radiotolerant tardigrade (2018)
  • Author(s): 柴原 礼良, 日詰 光治, 橋本 拓磨, 荒木 弘之, 國枝 武和
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] クマムシ固有の分泌型熱可溶性タンパク質SAHSの翻訳後修飾の解析Analysis of post-translational modifications of tardigrade-unique secretory heat soluble protein SAHS (2018)
  • Author(s): 田中彬寛、山口志保、國枝武和
  • Organizer: 第41回日本分子生物学会
• [Presentation] 乾燥耐性をもたないクマムシIsohypsibius myropsの放射線耐性 (2018)
  • Author(s): 西郷 永希子, 伊藤 麻紀子, 佐藤 勝也,國枝 武和
  • Organizer: 第41回日本分子生物学会
• [Presentation] Controlled Ecological Life Support System centered upon sweetpotato hydroponic culture in space in Tokushima University, Tokushima, November 1, 2018. (2018)
  • Author(s): Y. Kitaya
  • Organizer: Memorial Symposium for the Establishment of Institute of Space Nutrition
  • Int'l Joint Research / Invited
• [Presentation] Space Farming for Controlled Ecological Life Support (2018)
  • Author(s): Y. Kitaya
  • Organizer: Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences
  • Int'l Joint Research / Invited
• [Presentation] 極限環境に耐えるクマムシの耐性戦略を読み解く (2018)
  • Author(s): 國枝武和
  • Organizer: 第78回日本寄生虫学会東日本支部大会
  • Invited
• [Presentation] Negative regulation of HSV-1 Us3 kinase by tyrosine phosphorylation and its role in viral replication and pathogenesis (2018)
  • Author(s): Nami Kimura, Akihsa Kato, Yuhei Maruzuru, Naoto Koyanagi, Jun Arii, Yasushi Kawaguchi
  • Organizer: The 66th Annual Meeting of the Japanese Society of Virology
• [Presentation] HSV type-specific phosphorylation mediated by Us3 kinase; its role in viral pathogenesis and implication in evolution of herpesvirus (2018)
  • Author(s): Misato Shibazaki, Akihsa Kato, Kosuke Takeshima, Naoto Koyanagi, Yuhei Maruzuru, Jun Arii, Yasushi Kawaguchi
  • Organizer: The 66th Annual Meeting of the Japanese Society of Virology
• [Presentation] A single amino acid substitution in HSV-1 UL31 at an inter-hexamer contact site abrogates primary envelopment and viral growth (2018)
  • Author(s): Jun Arii, Kosuke Takeshima, Yuhei Maruzuru, Naoto Koyanagi, Akihisak Kato, Yasushi Kawaguchi
  • Organizer: The 66th Annual Meeting of the Japanese Society of Virology
• [Presentation] Residues in a-helix 9 of HSV-1 UL31 is critical for interaction with UL25 and incorporation of capsid into vesicles in the perinuclear space (2018)
  • Author(s): Misato Shibazaki, Akihsa Kato, Kosuke Takeshima, Naoto Koyanagi, Yuhei Maruzuru, Jun Arii, Yasushi Kawaguchi
  • Organizer: The 66th Annual Meeting of the Japanese Society of Virology
• [Presentation] The link between REM sleep loss and the desire for junk food (2018)
  • Author(s): Michael Lazarus
  • Organizer: European Sleep Research Society (ESRS)
  • Int'l Joint Research / Invited
• [Presentation] 月面農場における候補作物およびその栽培方法の提案 (2018)
  • Author(s): 北宅善昭, 渡邊博之
  • Organizer: 日本生物環境工学会2018年東京大会
• [Presentation] The rise of tardigrade-unique toolbox for extremotolerance (2018)
  • Author(s): Kunieda T
  • Organizer: 14th International Symposium on Tardigrada
  • Int'l Joint Research / Invited
• [Presentation] Tolerance to gamma radiation in the desiccation-sensitive tardigrade Isohypsibius myrops (Parachela, Eutardigrada) (2018)
  • Author(s): Saigo T, Ito M, Satoh K, Kubo T, Kunieda T
  • Organizer: 14th International Symposium on Tardigrada
  • Int'l Joint Research
• [Presentation] AFM analysis of DNA binding mode of a novel DNA-protection protein, Dsup, unique to a radiotolerant tardigrade (2018)
  • Author(s): Shibahara R, Hizume K, Hashimoto T, Araki H, Kubo T, Knieda T
  • Organizer: 14th International Symposium on Tardigrada
  • Int'l Joint Research
• [Presentation] 極限環境に耐えるクマムシの耐性戦略に迫る (2018)
  • Author(s): 國枝 武和
  • Organizer: 第一回再生学異分野融合研究会
  • Invited
• [Presentation] The link between REM sleep loss and the desire for junk food (2018)
  • Author(s): Michael Lazarus
  • Organizer: Federation of European Neuroscience Societies (FENS)
  • Int'l Joint Research / Invited
• [Presentation] Why do we fall asleep when bored? - The control of sleep and wakefulness by the nucleusaccumbens (2018)
  • Author(s): Michael Lazarus
  • Organizer: Japan Neuroscience Society
  • Int'l Joint Research / Invited
• [Presentation] A HSV-2 specific substrate of Us3 protein kinase dictates viral pathogenesis in mice following vaginal infection. (2018)
  • Author(s): M. Shibazaki, A. Kato, N. Koyanagi, Y. Maruduru, J. Arii, and Y. Kawaguchi
  • Organizer: 43th Annual International Herpesvirus Workshop 2018.
  • Int'l Joint Research
• [Presentation] Importance of air movements for properly controlling gas and heat exchanges between plants and the atmosphere under altered gravity conditions (2018)
  • Author(s): Y. Kitaya and H. Hirai
  • Organizer: COSPAR 2018
  • Int'l Joint Research
• [Presentation] Aquaponics integrated by lettuce hydroponics and loach aquaculture in CELSS (2018)
  • Author(s): Y. Kitaya, Y. Shimakawa, T. Shibuya, R. Endo, T. Wada and K. Nakamura
  • Organizer: COSPAR 2018
  • Int'l Joint Research
• [Presentation] 月面農場における作物栽培とシステムの提案 (2018)
  • Author(s): 渡邊博之、北宅善昭
  • Organizer: 2018生態工学会年次大会
• [Presentation] ドジョウとレタスを組み合わせたアクアポニックスの試行、第2報 気温とドジョウの有無がレタスの生育と成分含量に及ぼす影響 (2018)
  • Author(s): 和田光生、久保裕二、北宅善昭、中村謙治、西口正幸
  • Organizer: 2018生態工学会年次大会
• [Presentation] レタス水耕栽培とドジョウ養殖を組み合わせたアクアポニックスにおける植物成長および窒素フロー (2018)
  • Author(s): 北宅善昭、嶋川遥都波、和田光生、渋谷俊夫、遠藤良輔、中村謙治
  • Organizer: 2018生態工学会年次大会
• [Presentation] レタス栽培とドジョウ養殖を組み合わせたアクアポニックス実用化の可能性 (2018)
  • Author(s): 菊池真澄、中村謙治、和田光生、北宅善昭、西口正幸
  • Organizer: 2018生態工学会年次大会
• [Presentation] 重力拮抗遺伝子YAPによる三次元臓器形成メカニズム (2018)
  • Author(s): 浅岡 洋一, 仁科 博史, Carl-Philipp Heisenberg, 古谷-清木 誠
  • Organizer: 第41回日本分子生物学会年会
  • Invited
• [Presentation] 成熟β細胞で抑制されている遺伝子の解析 (2018)
  • Author(s): 西村 渉, 安田和基, 松本征仁, 岡崎康司, 野田泰子
  • Organizer: 第91回日本生化学会大会
• [Presentation] 閉鎖空間長期滞在モデルマウスの解析 (2018)
  • Author(s): 西村 渉, Tumurkhuu M.
  • Organizer: 宇宙生物科学会第32回大会
• [Presentation] 糖尿病の病態を反映するマーカー分子の探索 (2018)
  • Author(s): 西村 渉, Tumurkhuu M.
  • Organizer: 第8回国際医療福祉大学学会
• [Presentation] 膵β細胞の成熟・脱分化の分子メカニズムに関する研究 (2018)
  • Author(s): 西村 渉
  • Organizer: Islet Biology ’18
  • Invited
• [Presentation] 成熟膵島で抑制されている遺伝子の解析 (2018)
  • Author(s): 西村 渉, 安田和基, 松本征仁, 野田泰子
  • Organizer: 第61回糖尿病学会年次学術集会
• [Presentation] インスリン分泌抑制因子Necab1のGRを介した発現調節機構 (2018)
  • Author(s): 宇田川陽秀, 舟橋伸昭, 西村 渉, 平本正樹, 南茂隆生, 安田和基
  • Organizer: 第61回糖尿病学会年次学術集会
• [Presentation] Wolfram症候群をモデルとした細胞内ストレスによる膵β細胞可塑性制御の解明 (2018)
  • Author(s): 椎木幾久子, 田部勝也, 幡中雅行, 西村 渉, 佐藤吉彦, 駒津光久, 増谷 弘, 谷澤幸生
  • Organizer: 第61回糖尿病学会年次学術集会
• [Presentation] 高脂肪食にて活性増加する遺伝子cis調節領域の網羅的検討から見出された結合因子Nuclear respiratory factor 1 (Nrf1)の機能的検討 (2018)
  • Author(s): 南茂隆生, 宇田川陽秀, 舟橋伸昭, 川口美穂, 上番増喬, 平本正樹, 西村 渉, 安田和基
  • Organizer: 第61回糖尿病学会年次学術集会
• [Presentation] もうすぐ百周年の教室へ： 2年目の分子生物学教室の挑戦 (2018)
  • Author(s): 西村 渉
  • Organizer: 第84回岡山大学第一外科教室開講記念会
  • Invited
• [Presentation] 糖尿病における膵β細胞機能の回復と維持 (2018)
  • Author(s): 西村 渉
  • Organizer: 平成30年度鶴翔会（岡山医学同窓会）東京支部総会
  • Invited
• [Presentation] Sleep-dependent and independent brain clearance and the choroid plexus circadian rhythm (2018)
  • Author(s): Jihwan Myung
  • Organizer: 16th Annual meeting of Taiwan Society of Sleep Medicine (TSSM)
  • Int'l Joint Research / Invited
• [Presentation] 脳科学は養育者の潜在的な援助希求のサインを検出できるか？（公募シンポジウムS-57『それぞれの養育者にふさわしい支援を: 多職種・公私連携への提言』） (2018)
  • Author(s): 島田浩二
  • Organizer: 日本子ども虐待防止学会第24回学術集会
• [Presentation] 養育者の抑うつ気分を見える化して子育て困難の予防を図る: 社会脳の活動を計測し養育ストレスが深刻化する前兆を早期発見する評価法 (2018)
  • Author(s): 島田浩二, 友田明美
  • Organizer: JSTフェア2018
• [Presentation] 放射線によって生じるクラスターダメージの原子力間顕微鏡による解析 (2018)
  • Author(s): 中野敏彰，Xu Xu，金本僚太，平山亮一，鵜澤玲子，井出博
  • Organizer: 日本放射線影響学会第61回大会
• [Presentation] 原子間力顕微鏡を用いたクラスターDNA損傷の可視化 (2018)
  • Author(s): 中野敏彰，Xu Xu，金本僚太，平山亮一，鵜澤玲子，井出博
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] Direct observation of damage clustering in irradiated DNA (2018)
  • Author(s): Hiroshi Ide
  • Organizer: 15th International workshop on radiation damage to DNA
  • Int'l Joint Research / Invited
• [Presentation] コラーゲンが見えると培養が変わる！？ (2018)
  • Author(s): 三輪佳宏
  • Organizer: 平成30年度天然物化学セミナー
  • Invited
• [Presentation] コラーゲンが見えると培養が変わる！？ (2018)
  • Author(s): 三輪佳宏
  • Organizer: In vivoイメージングフォーラム2018
  • Invited
• [Presentation] 新規イメージング技術による線維化の定量的・経時的解析 (2018)
  • Author(s): 三輪佳宏、森夕海、田中順子、逆井智貴、水野聖哉、杉山文博、村谷匡史、高橋智
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] 睡眠・生体リズムの個人差 (2018)
  • Author(s): 北村真吾
  • Organizer: 日本生理人類学会第77回大会
  • Invited
• [Presentation] Molecular physiology in C. elegans body-wall muscles (2018)
  • Author(s): Higashitani A
  • Organizer: INDO-JAPAN Conference: Epigenetics, Human Microbiomes and Disease
  • Int'l Joint Research / Invited
• [Presentation] Development of 3D clinostat synchronized irradiation system for simulating space conditions (2018)
  • Author(s): Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Yoshida Y, Kanai T, Hada M, Saganti P, Takahashi A
  • Organizer: 2018 NASA Human Research Program Investigators' Workshop
  • Int'l Joint Research
• [Presentation] Effects of air velocities on photosynthesis, transpiration, and water use efficiencies of a plant canopy and single leaves (2018)
  • Author(s): Kitaya Y, Shibuya T, Tsuruyama J
  • Organizer: International Symposium on Agricultural Meteorology (ISAM2018)
  • Int'l Joint Research
• [Presentation] Decoding the Molecular Strategy of Radiotolerance in Extremotolerant Animal Model, Tardigrades (2018)
  • Author(s): Kunieda T
  • Organizer: The Endocrine Society’s 100th Annual Meeting
  • Int'l Joint Research / Invited
• [Presentation] ディープラーニングによる脳波/筋電データを用いたマウスの睡眠ステージ判定 (2018)
  • Author(s): 山部 剛士、堀江 和正、塩川 浩昭、柳沢 正史、北川 博之
  • Organizer: 第10回データ工学と情報マネジメントに関するフォーラム(DEIM2018)
• [Presentation] 宇宙環境に対する植物反応解析のための模擬太陽光人工光源ユニットの開発 (2018)
  • Author(s): 日出間純, 北宅善昭, 髙橋昭久
  • Organizer: 第32回宇宙環境利用シンポジウム
• [Presentation] 宇宙居住と宇宙放射線研究 (2018)
  • Author(s): 髙橋昭久
  • Organizer: 第32回宇宙環境利用シンポジウム
  • Invited
• [Presentation] Studies on skeletal muscle regeneration and atrophy; what zebrafish experienced in a space tour (2017)
  • Author(s): Sehara-Fujisawa A
  • Organizer: 第12回東京大学医科学研究所ネットワーク国際シンポジウム
  • Int'l Joint Research / Invited
• [Presentation] Muscle molecular physiology in spaceflown C. elegan (2017)
  • Author(s): Higashitani A
  • Organizer: 14th Japan-Korea Joint Seminar on Space Environment Utilization Research
  • Int'l Joint Research
• [Presentation] A heatstroke model in C. elegans (2017)
  • Author(s): Momma K, Homma T, Isaka R, Sudevan S, Higashitani A
  • Organizer: The 21th International C. elegans Meeting
  • Int'l Joint Research
• [Presentation] Mitochondrial dysfunction mediated ECM degradation in C. elegans (2017)
  • Author(s): Sudevan S, Takiura M, Kubota Y, Higashitani N, Higashitani A
  • Organizer: The 21th International C. elegans Meeting
  • Int'l Joint Research
• [Presentation] Forward genetic analysis of sleep in mice (2017)
  • Author(s): Hiromasa Funato, Masashi Yanagisawa
  • Organizer: Keystone symposia "State of the Brain"
  • Int'l Joint Research
• [Presentation] Hypothalamic Ptf1a is required for sexual differentiation of the brain and behavior (2017)
  • Author(s): Tomoyuki Fujiyama, Satoshi Miyashita, Yousuke Tsuneoka, Mai Nagaoka, Miyo Kakizaki, Satomi Kanno, Yukiko Ishikawa, Yoshiya Kawaguchi, Yuchio Yanagawa, Mark A. Magnuson, Yo-ichi Nabeshima, Masashi Yanagisawa, Hiromasa Funato, Mikio Hoshino
  • Organizer: Neuroscience 2017
  • Int'l Joint Research
• [Presentation] Incidence of circadian misalignment during stay in low-level light environments (2017)
  • Author(s): Shingo Kitamura, Akiko Hida, Michitaka Yoshimura, Kazuo Mishima
  • Organizer: 2017 Symposium of the Society for the Study of Human Biology & International Association of Physiological Anthropology
  • Int'l Joint Research
• [Presentation] Design and synthesis of orexin receptor selective ligands (2017)
  • Author(s): Nagase H
  • Organizer: 26th French-Japanese Symposium on Medicinal and Fine Chemistry
  • Int'l Joint Research / Invited
• [Presentation] Long term effects of noisy galvanic vestibular stimulation on postural stability in elderly adult (2017)
  • Author(s): Iwasaki S
  • Organizer: IFOS ENT World Congress
  • Int'l Joint Research
• [Presentation] Novel transgenic rat lines regulating the neuronal activity in rat vasopressin neuron by using Optogenetics and DREADDs technology (2017)
  • Author(s): Yoshimura M
  • Organizer: International Society for Autonomic Neuroscience (ISAN)
  • Int'l Joint Research
• [Presentation] C1 neurons mediate a stress-induced protection of renal ischemia/reperfusion injury (2017)
  • Author(s): Abe C
  • Organizer: International Society for Autonomic Neuroscience (ISAN)
  • Int'l Joint Research
• [Presentation] Comprehensive gene expression analysis of human fibroblasts after combined exposure to microgravity and heavy-ions for simulating space conditions (2017)
  • Author(s): Ikeda I, Muratani M, Puspitasari A, Held KD, Hidema J, Yoshida Y, Takahashi A
  • Organizer: The 7th International Society of Radiation Neurobiology Conference
  • Int'l Joint Research
• [Presentation] Effects of the combination of CO2 and cephalad fluid shift on dynamic cerebral autoregulation (2017)
  • Author(s): Kurazumi T, Iwasaki K, Ogawa Y, Yanagida R, Aoki K
  • Organizer: 16th International Symposium on Intracranial Pressure and Neuromonitoring in conjunction with the 6th Annual Meeting of the Cerebral Autoregulation Research Network
  • Int'l Joint Research
• [Presentation] Role of mechanosensitive channel in gravity sensing and responses against environmental stresses in ISS (2017)
  • Author(s): Furuichi T, Nakano M and Tatsumi H
  • Organizer: Plant Signaling and Behavior 2017 (PSB2017)
  • Int'l Joint Research
• [Presentation] Effects of long term running training on the responsiveness of genes to unloading in hindlimb muscles of rats (2017)
  • Author(s): Kawano F., Nakamura K., Ohsawa I., Masuzawa R., Konno R., Watanabe A., and Nakata K
  • Organizer: Cell Symposia: Exercise Metabolism
  • Int'l Joint Research
• [Presentation] Response of Pol II distribution to acute running in fast- and slow-twitch muscles of adult rats (2017)
  • Author(s): Masuzawa R., Tagawa D., Takemoto K., Ohsawa I., Watanabe A., and Kawano F
  • Organizer: Cell Symposia: Exercise Metabolism
  • Int'l Joint Research
• [Presentation] Workshop: Skin fungal microbiome of patients with Malassezia-related skin disease (2017)
  • Author(s): Sugita T, Cho O
  • Organizer: 15th International Congress of Mycology and Eukaryotic Microbiology
  • Int'l Joint Research
• [Presentation] Gene expression profile changes of human fibroblasts using device to synchronize carbon-ion irradiation and simulated microgravity (2017)
  • Author(s): Ikeda H, Muratani M, Puspitasari A, Held KD, Hidema J, Yoshida Y, Takahashi A
  • Organizer: ISSRPRT2017
  • Int'l Joint Research
• [Presentation] RNAseq profiling to analyze the combined effects on radiation under simulated microgravity for space biosciences (2017)
  • Author(s): Takahashi A, Ikeda H, Muratani M, Puspitasari A, Held KD, Hidema J, Yoshida Y
  • Organizer: 63rd Annual RRS Meeting
  • Int'l Joint Research
• [Presentation] Biological significance of CPD photolyase in rice grown under natural sunlight: UVB sensitivity and gene expression and subcellular localization of CPD photolyase (2017)
  • Author(s): Hidema J
  • Organizer: Symposium entitled DNA repair since the Nobel Prize, European Society of Photobiology Congress
  • Int'l Joint Research / Invited
• [Presentation] Effects of simulated microgravity on UV resistance of plants (2017)
  • Author(s): Hidema J
  • Organizer: 14th Japan-Korea Joint Seminar on Space Environment Utilization Research
  • Int'l Joint Research / Invited
• [Presentation] Acute effects of low-LET and high-LET radiation on fear memory formation and its underlying mechanisms (2017)
  • Author(s): Puspitasari A, Koganezawa N, Shirao T, Kojima N, Held KD, Takahashi A, Nakano T
  • Organizer: ISSRPRT2017
  • Int'l Joint Research
• [Presentation] How can we overcome tumor radioresistance; lessons from hypoxia biology (2017)
  • Author(s): Harada H
  • Organizer: 1st International Symposium on Radiation Therapeutics and Biology (isRTB-2017)
  • Int'l Joint Research / Invited
• [Presentation] The Causal Relationship between DNA Damage Induction in Bovine Lymphocytes and the Fukushima Nuclear Power Plant Accident (2017)
  • Author(s): Nakamura AJ, Suzuki M, Redon CE, Kuwahara Y, Yamashiro H, Abe Y, Takahashi S, Fukuda T, Isogai E, Bonner WM, Fukumoto M
  • Organizer: 2nd International Symposium of Quantum Beam Science at Ibaraki University
  • Int'l Joint Research
• [Presentation] Relative Effectiveness of Heavy Ion Irradiations from Accelerated Iron-56 Particles for Induction of Genotoxicity in the Hematopoietic System in Mice: Hematological Abnormality in the Peripheral Blood and Residual Damage in the Bone Marrow Erythrocytes (Part II) (2017)
  • Author(s): B.Wang, K.Tanaka, T.Katsube, Y.Ninomiya, H.Hirakawa, C.Liu, K.Maruyama, G.Vares, T.Nakajima, A.Nagamatsu, A.Fujimori, M.Nenoi
  • Organizer: The 63rd Annual International Meeting, Radiation Research Society
  • Int'l Joint Research
• [Presentation] FISH analysis of chromosomal aberrations in mouse splenocytes following total body irradiation with heavy ions (iron-56 ions) and X-rays (2017)
  • Author(s): T.Katsube, B.Wang, K.Tanaka, Y.Ninomiya, H.Hirakawa, C.Liu, K.Maruyama, G.Vares, T.Nakajima, A.Nagamatsu, A.Fujimori, M.Nenoi
  • Organizer: The 63rd Annual International Meeting, Radiation Research Society
  • Int'l Joint Research
• [Presentation] Evaluation of novel radiaoprotective drug and development of DNA damage monitoring micro-nano device for triage of radiation exposure (2017)
  • Author(s): Nakamura AJ, Tetsuka R, Takahashi K, Tamura T, Suzuki T and Hirayama R
  • Organizer: The 63rd Annual International Meeting, Radiation Research Society
  • Int'l Joint Research
• [Presentation] Hypoxia and radioresistance (2017)
  • Author(s): Harada H
  • Organizer: The 3rd Bordeaux Symposium
  • Int'l Joint Research
• [Presentation] Comparative exploration of biomarkers in mice exposed to X-ray or Fe-ion radiation (2017)
  • Author(s): T. Nakajima, G. Vares, Y. Ninomiya, B. Wang, T. Katsube, K. Tanaka, C. Liu, H.Hirakawa, K. Maruyama, A. Fujimori
  • Organizer: The 56th Annual Conference of the particle thrapy co-operative group
  • Int'l Joint Research
• [Presentation] Visualization of In Vivo DNA damage responses to galactic cosmic radiation (2017)
  • Author(s): A.Fujimori, H.Hirakawa, and L.Cuihua
  • Organizer: The 5th International Symposium on Space Radiation and Particle Radiotherapy
  • Int'l Joint Research
• [Presentation] Radiation-induced DNA-protein cross-links: mechanisms and significance (2017)
  • Author(s): Ide H
  • Organizer: US-Japan DNA Repair Meeting
  • Int'l Joint Research / Invited
• [Presentation] Closed plant factory in controlled ecological life support system in space (2017)
  • Author(s): Kitaya Y, Hirai H, Endo R, Shibuya T
  • Organizer: 2017 World Workshop of International Commission of Agricultural and Biosystems Engineering
  • Int'l Joint Research
• [Presentation] Decoding of unique strategy for extreme tolerance in tardigrades (2017)
  • Author(s): Kunieda T
  • Organizer: Vienna Biocenter Seminar
  • Int'l Joint Research / Invited
• [Presentation] 筋維持・萎縮機構の研究：宇宙から学ぶこと (2017)
  • Author(s): 瀬原淳子
  • Organizer: 第6回実験動物科学シンポジウム-宇宙における動物実験-
  • Invited
• [Presentation] 宇宙滞在が骨格筋に及ぼす影響―重力負荷減少だけではなさそう？ (2017)
  • Author(s): 佐藤文規、Choi Minyong、王梓，岩瀬海里、今村聖実、堀内映美、内田智子、小林純也、高橋昭久、菅野純夫、鈴木穣、川上浩一、瀬原淳子
  • Organizer: 日本宇宙生物科学会第３１回大会
• [Presentation] 筋タイプ特有のエピゲノムと遺伝子転写応答 (2017)
  • Author(s): 河野史倫
  • Organizer: Consortium of Biological Sciences 2017
• [Presentation] 14日間の閉鎖環境が循環調節機能に与える影響 (2017)
  • Author(s): 加藤智一、柳田亮、田子智晴、倉住拓弥、井上夏彦、鈴木豪、小川洋二郎、古川聡、岩崎賢一
  • Organizer: 第63回日本宇宙航空環境医学会大会
• [Presentation] 宇宙での身体の変化と宇宙医学（シンポジウム：宇宙環境における生体影響） (2017)
  • Author(s): 古川聡
  • Organizer: 第65回日本職業・災害医学会学術大会
  • Invited
• [Presentation] 宇宙環境における循環調節の変化（シンポジウム：宇宙環境における生体影響） (2017)
  • Author(s): 岩崎賢一
  • Organizer: 第65回日本職業・災害医学会学術大会
  • Invited
• [Presentation] ラット足底筋のヒストン修飾を変化させる運動条件の検討 (2017)
  • Author(s): 大沢育未、河野史倫
  • Organizer: 第72回日本体力医学会大会
• [Presentation] PGC-1遺伝子座における遅筋・速筋のエピゲノム相違と急性走運動に対する特異的転写制御 (2017)
  • Author(s): 増澤諒、大沢育未、田川大智、竹元玖乙、山田達也、河野史倫
  • Organizer: 第72回日本体力医学会大会
• [Presentation] 走運動歴を持つラットの後肢筋における廃用性萎縮応答の変化 (2017)
  • Author(s): 河野史倫、中村圭介、大沢育未、金野遼太朗、増澤諒
  • Organizer: 第72回日本体力医学会大会
• [Presentation] 経皮的ノイズ前庭電気刺激が歩行に及ぼす影響：両側前庭障害症例の検討 (2017)
  • Author(s): 岩﨑真一，藤本千里，木下淳，江上直也，鴨頭輝，牛尾宗貴，菅澤恵子，山岨達也
  • Organizer: 第117回日本耳鼻咽喉科学会総会
• [Presentation] 低周波騒音曝露が誘発する平衡感覚障害の解析 (2017)
  • Author(s): 大神信孝
  • Organizer: 第86回日本衛生学会学術総会
• [Presentation] ヒトの糖尿病においてβ細胞脱分化はβ細胞不全に関連する (2017)
  • Author(s): 椎木幾久子、田部勝也、幡中雅行、近藤 学、西村 渉、木村徳広、池田栄二、水上浩哉、佐藤吉彦、駒津光久、谷澤幸生
  • Organizer: 第60回日本糖尿病学会年次学術集
• [Presentation] シンポジウム：大気と宇宙微生物生態学の幕開け、国際宇宙ステーション与圧部の微生物モニタリングと群集構造 ---宇宙居住と地上応用--- (2017)
  • Author(s): 那須正夫、一條知昭、杉田隆
  • Organizer: 環境微生物系学会合同大会2017
• [Presentation] 新学術領域研究「宇宙に生きる」 (2017)
  • Author(s): 古川聡
  • Organizer: ConBio2017
  • Invited
• [Presentation] 植物の太陽粒子線障害に微小重力環境が及ぼす影響解析 (2017)
  • Author(s): 日出間純
  • Organizer: ConBio2017
  • Invited
• [Presentation] 搭載凍結受精卵から発生するマウスを用いた宇宙放射線の影響解析 (2017)
  • Author(s): 柿沼志津子、鶴岡千鶴、塚本智史、鬼頭靖司、小久保年章、和田彩子、島田義也、矢野幸子、鈴木智美、東端晃、多田基紀、鈴木ひろみ、嶋津徹
  • Organizer: 日本放射線影響学会第60回大会
  • Invited
• [Presentation] ISS搭載凍結受精卵から発生するマウスの宇宙放射線影響の解析Ⅱ (2017)
  • Author(s): 鶴岡千鶴、柿沼志津子、塚本智史、鬼頭靖司、小久保年章、和田彩子、島田義也、矢野幸子、鈴木智美、東端晃、多田紀、鈴木ひろみ、嶋津徹
  • Organizer: 日本宇宙生物科学会第31回大会
• [Presentation] 宇宙環境における宿主-病原体の相互作用の解析に向けた感染モデルの構築 (2017)
  • Author(s): 浅岡 洋一, 荻野 英賢, 白井 睦訓
  • Organizer: 第70回日本細菌学会中国・四国支部総会
• [Presentation] ヒト細胞の高LET放射線に対する応答におけるArtemisとXRCC4の機能 (2017)
  • Author(s): 勝部孝則、 劉 強、 謝 、王 冰
  • Organizer: 第40回日本分子生物学会年会・第90回日本生化学会大会
• [Presentation] 放射線が誘発するDNA-タンパク質クロスリンク損傷の解析 (2017)
  • Author(s): 松坂智幸，西村夕紀，徐徐，中野敏彰，平山亮一，鵜澤玲子，井出博
  • Organizer: 第40回日本分子生物学会年会
• [Presentation] DNA-タンパク質クロスリンク：検出と生物影響 (2017)
  • Author(s): 井出博
  • Organizer: 日本環境変異原学会第46回大会
• [Presentation] 酸化剤が誘発するDNA-タンパク質クロスリンク損傷の検出 (2017)
  • Author(s): 瀬畑敬文，久保山政弥，徐徐，Amir Salem，Mahmoud Shoulkamy，井出博，中野敏彰
  • Organizer: 第39回日本分子生物学会年会
• [Presentation] 放射線が誘発するクラスターDNA損傷の性状解析 (2017)
  • Author(s): 徐徐，金本僚太，松坂智幸，中野敏彰，平山亮一，鵜澤玲子，井出博
  • Organizer: 日本放射線影響学会第60回大会
• [Presentation] 宇宙滞在における放射線防護のためのバイオマーカーと防護剤の探索 (2017)
  • Author(s): 中島徹夫
  • Organizer: 日本放射線影響学会第60回大会
• [Presentation] X線照射後の生体応答に対する低酸素環境の役割に関する研究 (2017)
  • Author(s): 劉 翠華, 平川博一, 藤森 亮, 平山亮一
  • Organizer: 日本放射線影響学会第60回大会
• [Presentation] Piceatannolによる放射線防護効果の検討 (2017)
  • Author(s): 手塚諒哉、平山亮一、下川卓志、中村麻子
  • Organizer: 日本放射線影響学会第60回大会
• [Presentation] PDMSチップを用いたDNA損傷モニタリングシステムの開発 (2017)
  • Author(s): 高橋健太、田村隆大、鈴木孝明、中村麻子
  • Organizer: 日本放射線影響学会第60回大会
• [Presentation] 抗酸化剤による高LET放射線に対するDNA損傷防護効果の検討 (2017)
  • Author(s): 中村麻子、手塚諒哉、笹谷めぐみ、志村勉、神谷研二
  • Organizer: 日本宇宙生物科学会第31回大会
• [Presentation] 航空機放物飛行実験による微小重力下での植物栽培システム水循環 (2017)
  • Author(s): 北宅善昭、遠藤良輔、髙橋昭久、日出間純、橋本博文、稲富裕光
  • Organizer: 第32回宇宙環境利用シンポジウム
• [Presentation] 疑似宇宙環境における基本的生命現象の可視化 (2017)
  • Author(s): 沢野朝子
  • Organizer: 日本宇宙生物科学会第31回大会
• [Presentation] ベールを脱ぎ始めたクマムシの極限環境耐性メカニズム (2017)
  • Author(s): 國枝武和、橋本拓磨、堀川大樹、近藤小雪、田中冴、柴原礼良、桑原宏和、秦裕子、尾山大明、榎本敦、宮川清、原雄一郎、横堀伸一、小原雄治、藤山秋佐夫、久保健雄、荒川和晴、片山俊明
  • Organizer: ConBio2017
  • Invited
• [Presentation] 動物の極限環境耐性から生命の本質を探 (2017)
  • Author(s): 國枝武和
  • Organizer: 未来へのバイオ技術勉強会-超絶生物イノベーション
  • Invited
• [Presentation] 養育者の対乳幼児発話に関与する神経基盤の検討 (2017)
  • Author(s): 笠羽涼子, 島田浩二, 友田明美
  • Organizer: 第118回日本小児精神神経学会
• [Presentation] 養育者の抑うつ気分が社会的認知とその脳機能に及ぼす影響に関する実験的研究: 養育者支援によって子育て困難を低減するシステムの構築に向けた取り組み (2017)
  • Author(s): 島田浩二, 笠羽涼子, 藤澤隆史, 榊原信子, 滝口慎一郎, 友田明美
  • Organizer: 第118回日本小児精神神経学会
• [Presentation] 擬似微小重力環境における高精度重粒子線同期照射システムの開発 (2016)
  • Author(s): 高橋昭久 他
  • Organizer: 第62回日本宇宙航空環境医学会大会・日本宇宙生物科学会第30回大会
  • Place of Presentation: 名古屋
  • Year and Date: 2016-10-13
• [Presentation] 植物の重力感知・適応におけるカルシウムシグナルの役割 (2016)
  • Author(s): 古市卓也 他
  • Organizer: 第62回日本宇宙航空環境医学会大会・日本宇宙生物科学会第30回大会
  • Place of Presentation: 名古屋
  • Year and Date: 2016-10-13
• [Presentation] ISSを利用した植物の太陽粒子線による障害とその修復機構に微小重力環境が及ぼす影響解析 (2016)
  • Author(s): 日出間純 他
  • Organizer: 第62回日本宇宙航空環境医学会大会・日本宇宙生物科学会第30回大会
  • Place of Presentation: 名古屋
  • Year and Date: 2016-10-13
• [Presentation] 閉鎖環境ストレス下におけるストレス対処力の指標としてのSOC(Sence of Coherence)連続測定の試み (2016)
  • Author(s): 笹原信一朗
  • Organizer: 第62回日本宇宙航空環境医学会大会・日本宇宙生物科学会第30回大会
  • Place of Presentation: 名古屋
  • Year and Date: 2016-10-13
• [Presentation] c-fmsトランスジェニックメダカとc-fmsノックアウトメダカの駆使により明らかになった生体内破骨前駆細胞の動態 (2016)
  • Author(s): 茶谷昌宏 他
  • Organizer: 第34回日本骨代謝学会学術集会
  • Place of Presentation: 大阪
  • Year and Date: 2016-07-20
• [Presentation] Space Flight Experiment: Temporal Changes in the Skin Fungal Microbiomes of Astronauts in the International Space Station (2016)
  • Author(s): Sugita T et al.
  • Organizer: 30th International Symposium on Space Technology and Science
  • Place of Presentation: Kobe, Japan
  • Year and Date: 2016-07-04
  • Int'l Joint Research
• [Presentation] Effects of the combination of CO2 and cephalad fluid shift on dynamic cerebral autoregulation (2016)
  • Author(s): Kurazumi T and Iwasaki K et al.
  • Organizer: 16th International Symposium on Intracranial Pressure and Neuromonitoring in conjunction with the 6th Annual Meeting of the Cerebral Autoregulation Research Network
  • Place of Presentation: Cambridge, MA, USA
  • Year and Date: 2016-06-28
  • Int'l Joint Research
• [Presentation] 宇宙微生物学への招待～国際宇宙ステーションにおけるgene ecology～ (2016)
  • Author(s): 那須正夫
  • Organizer: 第14回日本予防医学会学術総会
  • Place of Presentation: 東京
  • Year and Date: 2016-06-18
  • Invited
• [Presentation] 宇宙で過ごした魚の骨格筋はやせるのか？ -宇宙実験の結果より- (2016)
  • Author(s): 佐藤文規
  • Organizer: 第14回日本予防医学会学術総会
  • Place of Presentation: 東京
  • Year and Date: 2016-06-18
• [Presentation] 国際宇宙ステーション「きぼう」における細菌モニタリング (2016)
  • Author(s): 一條知昭
  • Organizer: 第14回日本予防医学会学術総会
  • Place of Presentation: 東京
  • Year and Date: 2016-06-18
• [Presentation] 有人閉鎖環境滞在研究におけるNIRS活用の試み (2016)
  • Author(s): 村井正
  • Organizer: 第14回日本予防医学会学術総会
  • Place of Presentation: 東京
  • Year and Date: 2016-06-18
• [Presentation] Symposium Bone I Biomarker in skeletomusucular system: Muscle-derived factor affecting bone metabolism (2016)
  • Author(s): Kaji H
  • Organizer: The 4th Seoul International Congress of Endocrinology and Metabolism (SICEM 2016)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-04-28
  • Int'l Joint Research
• [Presentation] 新たな視点で環境中の微生物をとらえる ―家庭から宇宙居住まで― (2016)
  • Author(s): 那須正夫
  • Organizer: 第33回空気清浄とコンタミネーションコントロール研究大会
  • Place of Presentation: 東京
  • Year and Date: 2016-04-19
• [Presentation] Roles of Meltrin β/ADAM19 in development of the heart (2016)
  • Author(s): Atsuko Sehara-Fujisawa
  • Organizer: Swiss-Kyoto Joint Symposium of Life Science 2016
  • Place of Presentation: Kyoto, Japan
  • Int'l Joint Research / Invited
• [Presentation] Introduction of a project study entitled “Modification Effect from Chronic Restraint-Induced Stress on Mouse Radiosusceptibility (2016)
  • Author(s): Wang B and Nenoi M et al.
  • Organizer: Workshop of Radiation Medicine and Protection
  • Place of Presentation: Tianjin, P.R. China
  • Int'l Joint Research / Invited
• [Presentation] The potential of medaka fish to uncover mechanisms of osteoclastogenesis (2016)
  • Author(s): Chatani M
  • Organizer: 13th Meeting of Bone Biology Forum
  • Place of Presentation: Chiba, Japan
  • Int'l Joint Research / Invited
• [Presentation] Effects of chronic restraint-induced stress on radiation-induced chromosomal aberrations in mouse splenocytes (2016)
  • Author(s): Katsube T and Nenoi M et al.
  • Organizer: Workshop of Radiation Medicine and Protection
  • Place of Presentation: Tianjin, P.R. China.
  • Int'l Joint Research
• [Presentation] Effect of noisy galvanic vestibular stimulation on locomotion in patients with bilateral vestibular dysfunction (2016)
  • Author(s): Iwasaki S and Morita H et al.
  • Organizer: 2016 Annual CORLAS Meeting
  • Place of Presentation: Bordeaux, France