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Frontiers in Chemical Communications

Administrative Group

Project AreaFrontier research of chemical communications
Project/Area Number 17H06400
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionKyoto University

Principal Investigator

Kakeya Hideaki  京都大学, 薬学研究科, 教授 (00270596)

Co-Investigator(Kenkyū-buntansha) 松永 茂樹  東京大学, 大学院農学生命科学研究科(農学部), 教授 (60183951)
西尾 和人  近畿大学, 医学部, 教授 (10208134)
入江 一浩  京都大学, 農学研究科, 教授 (00168535)
村田 道雄  大阪大学, 理学研究科, 教授 (40183652)
上田 実  東北大学, 理学研究科, 教授 (60265931)
上杉 志成  京都大学, 化学研究所, 教授 (10402926)
菊地 和也  大阪大学, 工学研究科, 教授 (70292951)
榊原 康文  慶應義塾大学, 理工学部(矢上), 教授 (10287427)
BOONE CHARLES  国立研究開発法人理化学研究所, 環境資源科学研究センター, チームリーダー (70601342)
長田 裕之  国立研究開発法人理化学研究所, 環境資源科学研究センター, グループディレクター (80160836)
河岸 洋和  静岡大学, グリーン科学技術研究所, 教授 (70183283)
Project Period (FY) 2017-06-30 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥158,080,000 (Direct Cost: ¥121,600,000、Indirect Cost: ¥36,480,000)
Fiscal Year 2021: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
Fiscal Year 2020: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
Fiscal Year 2019: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
Fiscal Year 2018: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
Fiscal Year 2017: ¥21,840,000 (Direct Cost: ¥16,800,000、Indirect Cost: ¥5,040,000)
Keywords化学コミュニケーション / 分子社会学 / 天然物化学 / ケミカルバイオロジー / 生物活性リガンド
Outline of Final Research Achievements

Essential roles of natural products as chemical communication molecules among microbes, animals, plants, et cetera have not been fully elucidated. In this research project, we established the innovative high-order analysis platforms including bioimaging, chemical proteomics, chemical genetics/genomics, and AI-driven bioinformatics, clarifying essential roles of natural products/bioactive synthetic ligands as chemical communication molecules in the natural environment. In addition, this research project contributed to the advancement in medical, agricultural, and food sciences by developing useful chemical tools as well as pharmaceuticals/agrochemicals leads, opening up a new discipline, “Molecular Sociology”, which focuses on the frontiers in chemical communications in a variety of biological species. We also performed an international collaboration, leading to international network development and bringing up young scientist broader views and higher expertise.

Academic Significance and Societal Importance of the Research Achievements

本学術領域は、生体分子科学関連分野において、国際的にも格段にリード可能な「生物活性リガンドを起点とした化学コミュニケーションのフロンティア」領域を構築するものとなった。本学術領域の推進により、化学、生物学など理工系学問分野の垣根を超越し、分子科学領域を情報科学・ケミカルバイオロジー・生命科学へリンクさせ、自然環境における生物間コミュニケーションの解明と制御を主体とした新学問分野「分子社会学」の礎が構築されたことは特筆に値する。得られた多くの研究成果は、学術的に意義深いのみならず、今後、医薬品・農薬・食糧などの開発に大きく寄与することが期待される。

Report

(6 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (41 results)

All 2021 2019 2018 Other

All Int'l Joint Research (30 results) Remarks (2 results) Funded Workshop (9 results)

  • [Int'l Joint Research] プリンストン/ミネソタ大学/ストニーブルック大学(米国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] トロント大学/マギル大学(カナダ)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] フランクフルト大学/トリーア大学/ライプニッツ天然有機化合物研究所(ドイツ)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] スイス連邦工科大学(スイス)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] 復旦大学/浙江大学/The National Center for Drug Screening(中国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] プリンストン/ミネソタ大学/ストニーブルック大学(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] トロント大学/マギル大学(カナダ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] フランクフルト大学/トリーア大学/ライプニッツ天然有機化合物研究所(ドイツ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] スイス連邦工科大学(スイス)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] 復旦大学/浙江大学/The National Center for Drug Screening(中国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] プリンストン/ミネソタ大学/ストニーブルック大学(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] トロント大学/マギル大学(カナダ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] フランクフルト大学/トリーア大学/ライプニッツ天然有機化合物研究所(ドイツ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] スイス連邦工科大学(スイス)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] 復旦大学/浙江大学/The National Center for Drug Screening(中国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] プリンストン大学/ミネソタ大学/ストニーブルック大学(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] トロント大学/マギル大学(カナダ)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] フランクフルト大学/トリーア大学/ライプニッツ天然有機化合物研究所(ドイツ)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] スイス連邦工科大学(スイス)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] 復旦大学/浙江大学/The National Center for Drug Screening(中国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] プリンストン大学/ミネソタ大学/ストニーブルック大学(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] トロント大学/マギル大学(カナダ)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] フランクフルト大学/マックスプランク研究所/ライプニッツ天然有機化合物研究所(ドイツ)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] スイス連邦工科大学(スイス)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] 復旦大学/浙江大学/The National Center for Drug Screening(中国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2017 Annual Research Report
  • [Remarks] 「化学コミュニケーションのフロンティア」領域ホームページ

    • URL

      https://www.pharm.kyoto-u.ac.jp/fr_chemcomm/index.html

    • Related Report
      2021 Annual Research Report 2020 Annual Research Report 2019 Annual Research Report
  • [Remarks] 化学コミュニケーションのフロンティア

    • URL

      http://www.pharm.kyoto-u.ac.jp/fr_chemcomm/

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Funded Workshop] The 2nd International Symposium on Chemical Communication (ISCC2021)2021

    • Related Report
      2021 Annual Research Report
  • [Funded Workshop] Asian Chemical Biology Initiative 2021 Jerusalem Meeting (on line)2021

    • Related Report
      2020 Annual Research Report
  • [Funded Workshop] 15th International Symposium on Applied Bioinorganic Chemistry (ISABC19)2019

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] The 27th International Society of Heterocyclic Chemistry Congress (The 27th ISHC Congress))2019

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] Marine Biotechnology Conference 20192019

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] The 1st International Symposium on Chemical Communications2019

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] Asian Chemical Biology Initiative 2019 Yangon Meeting2019

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] The 16th Asia Pacific Bioinformatics Conference 20182019

    • Related Report
      2017 Annual Research Report
  • [Funded Workshop] International Seminar on Biophysics and Chemical Biology of Biomembrane and Lipid Bilayers2018

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2017-07-04   Modified: 2023-01-30  

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