発動分子科学：エネルギー変換が拓く自律的機能の設計（総括）

• Project Area: Molecular Engine: Design of Autonomous Functions through Energy Conversion
• Project/Area Number: 18H05418
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Complex systems
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: 金原 数 東京工業大学, 生命理工学院, 教授 (30282578)
• Co-Investigator(Kenkyū-buntansha): 上野 隆史 東京工業大学, 生命理工学院, 教授 (70332179)
• Project Period (FY): 2018-06-29 – 2023-03-31
• Project Status: Completed (Fiscal Year 2022)
• Budget Amount: ¥105,170,000 (Direct Cost: ¥80,900,000、Indirect Cost: ¥24,270,000); Fiscal Year 2022: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000); Fiscal Year 2021: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000); Fiscal Year 2020: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000); Fiscal Year 2019: ¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000); Fiscal Year 2018: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
• Keywords: 発動分子 / 分子機械 / 分子モーター / ソフトロボット / エネルギー変換 / 集団運動 / アクティブマター / ハイブリッド分子 / 分子エンジン / 人工分子機械 / 生体分子機械

Outline of Annual Research Achievements

領域最終年度の活動として，以下を実施した。（１）領域の研究成果報告と将来的な研究連携推進のための領域会議を2022年5月と2022年11月に対面形式で実施した。これにより領域期間全体の成果について意識共有することができた。（2）昨年度に引き続き，産官学連携活動（ME-Innov）として，領域の研究内容の相互に理解し，連携活動を円滑に推進することを目的として，複数の企業研究者と領域参加メンバーによるセミナーおよび意見交換会を実施した。また，発動分子科学終了後の将来的な長期展望を決めるための情報収集を行った。（3）昨年度に引き続き，関連分野の最新動向と，共同研究，連携研究推進のための情報を得ることを目的として，各分野で活躍する研究者を講師とした発動分子科学セミナーを実施した。対面形式とオンラインとを併用することにより，海外の研究者を含め多様な講師を招くことができた。（４）領域メンバーの自由闊達な意見交換の場として，オンライン形式での「発動分子懇談会」を定期的に開催した。（５）SNSおよび領域ホームページを通じて領域の活動状況と研究成果の公開を行った。（６）昨年度に引き続き，関連学会におけるシンポジウムや研究会を主催・共催し，領域活動の周知につとめた。（７）領域期間全体の成果を公開することを目的として，成果発表会を2023年3月および2023年9月に実施した。（８）領域期間全体の研究成果および活動実績をまとめた報告書を作成し，関係者に配付することで成果の発信につとめた。

Research Progress Status

令和4年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和4年度が最終年度であるため、記入しない。

Research Products

• [Int'l Joint Research] Bordeaux大(フランス)
• [Int'l Joint Research] Manchester大(英国)
• [Int'l Joint Research] Bristol大学(英国)
• [Int'l Joint Research] IECB(フランス)
• [Int'l Joint Research] IECB(フランス)
• [Int'l Joint Research] Bristol大学(英国)
• [Int'l Joint Research] ボルド－大学(フランス)
• [Int'l Joint Research] アイルランド国立大学(アイルランド)
• [Int'l Joint Research] 精華大学(中国)
• [Int'l Joint Research] マサチューセッツ工科大学(米国)
• [Int'l Joint Research] ボルドー大学/CNRS/IECB(フランス)
• [Int'l Joint Research] アイルランド国立大学(アイルランド)
• [Journal Article] Sensitivity Tuning of 9,10-Di(piperazinyl)anthracene Derivatives for Amphiphilic Assemblies by pH and Side-chain Modification with Monodisperse Oligo(ethylene glycol)s (2023)
  • Author(s): Adachi Junya、Kinbara Kazushi
  • Journal Title: Chemistry Letters Volume: 52 Issue: 3 Pages: 218-221
  • DOI: 10.1246/cl.230025
  • Peer Reviewed
• [Journal Article] Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection (2023)
  • Author(s): Adachi Junya、Oda Haruka、Fukushima Toshiaki、Lestari Beni、Kimura Hiroshi、Sugai Hiroka、Shiraki Kentaro、Hamaguchi Rei、Sato Kohei、Kinbara Kazushi
  • Journal Title: Analytical Chemistry Volume: 95 Issue: 12 Pages: 5196-5204
  • DOI: 10.1021/acs.analchem.2c04133
  • Peer Reviewed / Open Access
• [Journal Article] Synthesis and properties of multiblock amphiphilic cyclophanes with chiral aromatic units (2023)
  • Author(s): Matsuda Ryoto、Otake Haruki、Sato Kohei、Kinbara Kazushi
  • Journal Title: Polymer Journal Volume: 55 Issue: 11 Pages: 1225-1229
  • DOI: 10.1038/s41428-023-00812-6
  • Peer Reviewed
• [Journal Article] Supramolecular Mechanosensitive Potassium Channel Formed by Fluorinated Amphiphilic Cyclophane (2022)
  • Author(s): Sato Kohei、Sasaki Ryo、Matsuda Ryoto、Nakagawa Mayuko、Ekimoto Toru、Yamane Tsutomu、Ikeguchi Mitsunori、Tabata Kazuhito V.、Noji Hiroyuki、Kinbara Kazushi
  • Journal Title: Journal of the American Chemical Society Volume: 144 Issue: 26 Pages: 11802-11809
  • DOI: 10.1021/jacs.2c04118
  • Peer Reviewed
• [Journal Article] Multiblock Amphiphilic Triptycene toward Bioinspired Molecular Rotor in Membrane (2022)
  • Author(s): Yospanya Wijak、Sato Kohei、Kinbara Kazushi
  • Journal Title: Chemistry Letters Volume: 51 Issue: 10 Pages: 1026-1028
  • DOI: 10.1246/cl.220360
  • Peer Reviewed
• [Journal Article] Calcium-induced reversible assembly of phosphorylated amphiphile within lipid bilayer membranes (2021)
  • Author(s): Shimizu Yusuke、Sato Kohei、Kinbara Kazushi
  • Journal Title: Chemical Communications Volume: 57 Issue: 34 Pages: 4106-4109
  • DOI: 10.1039/d1cc01111a
  • Peer Reviewed
• [Journal Article] Properties of Imidazolinium-containing Multiblock Amphiphile in Lipid Bilayer Membranes (2021)
  • Author(s): Mori Miki Mori, Kinbara Kazushi
  • Journal Title: Journal of Photopolymer Science and Technology Volume: 34 Pages: 161-165
  • NAID: 130008119674
  • Peer Reviewed
• [Journal Article] Supramolecular Transmembrane Ion Channels Formed by Multiblock Amphiphiles (2021)
  • Author(s): Sato Kohei、Muraoka Takahiro、Kinbara Kazushi
  • Journal Title: Accounts of Chemical Research Volume: 54 Issue: 19 Pages: 3700-3709
  • DOI: 10.1021/acs.accounts.1c00397
  • Peer Reviewed
• [Journal Article] Chemical Molecular Machines and Robots (2021)
  • Author(s): Kinbara Kazushi
  • Journal Title: Encyclopedia of Robotics Volume: 1 Pages: 1-13
  • DOI: 10.1007/978-3-642-41610-1_211-1
  • ISBN: 9783642416101
  • Peer Reviewed
• [Journal Article] Synthetic Ion Channel Formed by Multiblock Amphiphile with Anisotropic Dual-Stimuli-Responsiveness (2021)
  • Author(s): Sasaki Ryo、Sato Kohei、Tabata Kazuhito V.、Noji Hiroyuki、Kinbara Kazushi
  • Journal Title: Journal of the American Chemical Society Volume: 143 Issue: 3 Pages: 1348-1355
  • DOI: 10.1021/jacs.0c09470
  • Peer Reviewed
• [Journal Article] Imidazolinium‐based Multiblock Amphiphile as Transmembrane Anion Transporter (2020)
  • Author(s): Mori Miki、Sato Kohei、Ekimoto Toru、Okumura Shinichi、Ikeguchi Mitsunori、Tabata Kazuhito V.、Noji Hiroyuki、Kinbara Kazushi
  • Journal Title: Chemistry - An Asian Journal Volume: 16 Issue: 2 Pages: 147-157
  • DOI: 10.1002/asia.202001106
  • Peer Reviewed
• [Journal Article] Thermo-driven self-assembly of a PEG-containing amphiphile in a bilayer membrane (2020)
  • Author(s): Li Rui、Muraoka Takahiro、Kinbara Kazushi
  • Journal Title: RSC Advances Volume: 10 Issue: 43 Pages: 25758-25762
  • DOI: 10.1039/d0ra03920a
  • Peer Reviewed / Open Access
• [Journal Article] A synthetic ion channel with anisotropic ligand response (2020)
  • Author(s): Muraoka Takahiro, Noguchi Daiki, Kasai Rinshi, Sato Kohei, Sasaki Ryo, Tabata Kazuhito, Ekimoto Toru, Ikeguchi Mitsunori, Kamagata Kiyoto, Hoshino Norihisa, Noji Hiroyuki, Akutagawa Tomoyuki, Ichimura Kazuaki, Kinbara Kazushi
  • Journal Title: Nature Communications Volume: 11 Issue: 1 Pages: 2924-2924
  • DOI: 10.1038/s41467-020-16770-z
  • NAID: 120006878529
  • Peer Reviewed / Open Access
• [Journal Article] Reversible formation of multiple stimuli-responsive polymeric materials through processing control of trifunctional amphiphilic molecules (2020)
  • Author(s): Muraoka Takahiro、Honda Hidetaka、Nabeya Kota、Kinbara Kazushi
  • Journal Title: Chemical Communications Volume: 56 Issue: 57 Pages: 7881-7884
  • DOI: 10.1039/d0cc02716b
  • Peer Reviewed
• [Journal Article] タンパク質を模倣した人工発動分子の創製に向けて -膜タンパク質を模倣した合成化学的アプローチ-, (2020)
  • Author(s): 金原 数
  • Journal Title: 化学と工業 Volume: 73 Pages: 457-459
  • Peer Reviewed
• [Journal Article] Aromatic Fluorination of Multiblock Amphiphile Enhances Its Incorporation into Lipid Bilayer Membranes (2020)
  • Author(s): Sasaki Ryo, Sato Kohei, Kinbara Kazushi
  • Journal Title: ChemistryOpen Volume: 9 Issue: 3 Pages: 301-303
  • DOI: 10.1002/open.201900374
  • Peer Reviewed / Open Access
• [Journal Article] New Modified Deoxythymine with Dibranched Tetraethylene Glycol Stabilizes G-quadruplex Structures (2020)
  • Author(s): H. Tateishi-Karimata, T. Ohyama, T. Muraoka, S. Tanaka, K. Kinbara, and N. Sugimoto
  • Journal Title: Molecules Volume: 25 Issue: 3 Pages: 705-705
  • DOI: 10.3390/molecules25030705
  • NAID: 120006811187
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Introduction: Molecular Motors (2020)
  • Author(s): Iino Ryota、Kinbara Kazushi、Bryant Zev
  • Journal Title: Chemical Reviews Volume: 120 Issue: 1 Pages: 1-4
  • DOI: 10.1021/acs.chemrev.9b00819
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Session 2SDA―Nonequilibrium energetics of biological molecular machines (2020)
  • Author(s): Toyabe Shoichi, Li Chun-Biu, Kinbara Kazushi
  • Journal Title: Biophysical Reviews Volume: 12 Issue: 2 Pages: 273-274
  • DOI: 10.1007/s12551-020-00634-3
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 1.Development of an Engineered Photoactive Yellow Protein as a Cross-Linking Junction for Construction of Photoresponsive Protein-Polymer Conjugates (2019)
  • Author(s): Ui, Mihoko; Miyauchi, Yusuke; Inoue, Masataka; Murakami, Makoto; Araki, Yasuyuki; Wada, Takehiko; Kinbara, Kazushi
  • Journal Title: ChemPhotoChem Volume: 3 Issue: 6 Pages: 356-360
  • DOI: 10.1002/cptc.201900024
  • Peer Reviewed
• [Journal Article] Heat-Triggered Crystallization of Liquid Crystalline Macrocycles Allowing for Conductance Switching through Hysteretic Thermal Phase Transitions (2018)
  • Author(s): Muraoka Takahiro、Shima Tatsuya、Kajitani Takashi、Hoshino Norihisa、Morvan Estelle、Grelard Axelle、Dufourc Erick J.、Fukushima Takanori、Akutagawa Tomoyuki、Nabeya Kota、Kinbara Kazushi
  • Journal Title: Chemistry - An Asian Journal Volume: 14 Issue: 1 Pages: 141-148
  • DOI: 10.1002/asia.201801372
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Localization of transmembrane multiblock amphiphilic molecules in phase-separated vesicles (2018)
  • Author(s): Kazushi Kinbara, Kaori Umetsu, Hiroki Sonobe, Takahiro Muraoka, Naofumi Shimokawa, Masahiro Takagi
  • Journal Title: Faraday Discussions Volume: 印刷中 Pages: 315-328
  • DOI: 10.1039/c8fd00022k
  • Peer Reviewed
• [Presentation] Development of Anthracene-Based Fluorescent Probes for Application in Cellular Systems (2022)
  • Author(s): Junya Adachi, Toshiaki Fukushima, Haruka Oda, Hiroka Sugai, Kohei Sato, Hiroshi Kimura, Kazushi Kinbara
  • Organizer: The 19th International Symposium on Novel Aromatic Compounds
  • Int'l Joint Research
• [Presentation] Multiblock Amphiphilic Molecules as Synthetic Mimics of Transmembrane Channel-forming Proteins (2022)
  • Author(s): Kazushi Kinbara
  • Organizer: 10th Asian Biological Inorganic Chemistry Conference (AsBIC10)
  • Int'l Joint Research / Invited
• [Presentation] Design of Multiblock Amphiphilic Molecules for Ion Transportation Across Membranes (2022)
  • Author(s): Kazushi Kinbara
  • Organizer: 4th International Conference on Emerging Advanced Nanomaterials (ICEAN 2022)
  • Int'l Joint Research / Invited
• [Presentation] 非TICT型粘度応答性蛍光プローブの開発と生細胞イメージングへの適用 (2022)
  • Author(s): 足立惇弥, 福嶋 俊明, 小田 春佳, 菅井 祥加, 佐藤 浩平, 木村 宏, 金原 数
  • Organizer: 2022年光化学討論会
• [Presentation] Development of cyclic oligo(ethylene glycol) for suppression of amyloid protein fibrillation, (2022)
  • Author(s): Thirasara Sammani, Wijak Yospanya, Adam M. Wawro, Kohei Sato, Kazushi Kinbara
  • Organizer: 第71回高分子討論会
• [Presentation] Amphiphilic oligo(ethylene glycol)s as protein stabilizers: effect of structure (2022)
  • Author(s): Wijak Yospanya, Thirasara Sammani, Kohei Sato, Adam M. Wawro, Kazushi Kinbara
  • Organizer: 第71回高分子討論会
• [Presentation] Development of multiblock amphiphilic cyclophanes and their functions within lipid bilayer membranes (2022)
  • Author(s): Ryoto Matsuda, Kohei Sato, Kazushi Kinbara
  • Organizer: 第71回高分子討論会
• [Presentation] Thermal diffusivity of structured poly(ethylene glycols) (2022)
  • Author(s): Mitsuhiro Matsumoto, Meguya Ryu, Kohei Sato, Anna Ishikawa, Takashi Kajitani, Yoshihisa Sei, Nobutaka Honma, Katsuhiko Nakajima, Junzo Ukai, Junko Morikawa, Kazushi Kinbara
  • Organizer: 第71回高分子討論会
• [Presentation] 非対称構造を有する膜貫通型両親媒性分子の開発 (2022)
  • Author(s): 大熊 葵, 佐藤 浩平, 金原 数
  • Organizer: 第71回高分子学会年次大会
• [Presentation] 構造化大環状ポリアミドによる超分子構造体の構築 (2022)
  • Author(s): 中村 彰吾, 玉田 浩之, 佐藤 浩平, 金原 数
  • Organizer: 第71回高分子学会年次大会
• [Presentation] 水中における過渡的な両親媒性分子生成サイクルの構築 (2022)
  • Author(s): 中川 優芽, 森 未妃, 佐藤 浩平, 金原 数
  • Organizer: 第71回高分子学会年次大会
• [Presentation] Hybrid kinesin-1 dimer conjugated with synthetic PEG linker shows processive and fast motion with robust hand-over-hand mechanism (2022)
  • Author(s): Jakia Jannat Keya, Akasit Visootsat, Kimitoshi Takeda, Akihiro Otomo, Wijak Yospanya, Sanghun Han, Kazushi Kinbara, Ryota Iino
  • Organizer: 第60回日本生物物理学会年会
• [Presentation] QM/MM simulations of cyclic artificial ion channel in membrane-water system (2022)
  • Author(s): Mayuko Nakagawa, Toru Ekimoto, Tsutomu Yamane, Kohei Sato, Kazushi Kinbara, Mitsunori Ikeguchi
  • Organizer: 第60回日本生物物理学会年会
• [Presentation] フッ素化人工チャネルによる膜間物質輸送 (2022)
  • Author(s): 佐藤 浩平, 金原 数
  • Organizer: 第16回バイオ関連化学シンポジウム
• [Presentation] Development of functional anthracene-based multiblock fluorophore for visualization of biological environment (2022)
  • Author(s): Junya Adachi , Kohei Sato , Kazushi Kinbara
  • Organizer: 日本化学会 第102春季年会
• [Presentation] 両親媒性分子の過渡的な生成に基づく化学反応サイクルの構築 (2022)
  • Author(s): 中川 優芽 , 森 未妃 , 佐藤 浩平 , 金原 数
  • Organizer: 日本化学会 第102春季年会
• [Presentation] 構造化大環状ポリアミドの自己集合 (2022)
  • Author(s): 中村 彰吾 , 玉田 浩之 , 佐藤 浩平 , 金原 数
  • Organizer: 日本化学会 第102春季年会
• [Presentation] An artificial ion channel studied by all-atom molecular dynamics simulations (2021)
  • Author(s): 中川真由子 , 浴本亨 , 山根努 , 村岡貴博 , 佐藤浩平 , 金原数 , 池口満徳
  • Organizer: 第21回日本蛋白質科学会年会
• [Presentation] 発光性マルチブロック両親媒性分子の合成と発光特性 (2021)
  • Author(s): 足立 惇弥 , 佐藤 浩平 , 金原 数
  • Organizer: 発動分子科学研究会
• [Presentation] フッ素化交互両親媒性分子による超分子イオンチャネルの構築 (2021)
  • Author(s): 佐藤 浩平 , 佐々木 崚 , 田端 和仁 , 野地 博行 , 金原 数
  • Organizer: 第 31 回バイオ・高分子シンポジウム
• [Presentation] Development of cyclic oligo(ethylene glycol) for suppression of amyloid protein fibrillation (2021)
  • Author(s): Thirasara Sammani , Wijak Yospanya , Adam M. Wawro , Kohei Sato , Kazushi Kinbara
  • Organizer: 発動分子科学研究会
• [Presentation] Transmembrane Ion Transport by Fluorinated Amphiphilic Cyclophanes (2021)
  • Author(s): Kohei Sato , Ryo Sasaki , Ryoto Matsuda , Kazuhito V. Tabata , Hiroyuki Noji , Kazushi Kinbara
  • Organizer: 発動分子科学研究会
• [Presentation] 膜タンパク質を模倣した交互両親媒性分子の階層的集合化と機能発現 (2021)
  • Author(s): 佐藤浩平 , 佐々木崚 , 田端和仁 , 野地博行 , 金原数
  • Organizer: 第70回高分子討論会
• [Presentation] Fluorinated multiblock amphiphiles and their transmembrane ion transport properties (2021)
  • Author(s): Kohei Sato , Ryo Sasaki , Kazuhito Tabata , Hiroyuki Noji , Kazushi Kinbara
  • Organizer: Pacifichem 2021
• [Presentation] Development of chiral multiblock amphiphiles and their functions within lipid bilayer membranes (2021)
  • Author(s): Ryoto Matsuda , Kohei Sato , Ryo Sasaki , Kazuhito Tabata , Hiroyuki Noji , Kazushi Kinbara
  • Organizer: Pacifichem 2021
• [Presentation] Multiblock amphiphile bearing imidazolinium as transmembrane anion transporter (2021)
  • Author(s): Miki Mori , Kohei Sato , Toru Ekimoto , Shinichi Okumura , Mitsunori Ikeguchi , Kazuhito Tabata , Hiroyuki Noji , Kazushi Kinbara
  • Organizer: Pacifichem 2021
• [Presentation] Synthesis of anthracene-based multiblock amphiphile and its stimuli-responsiveness within phospholipid membranes (2021)
  • Author(s): Junya Adachi , Kohei Sato , Kazushi Kinbara
  • Organizer: Pacifichem 2021
• [Presentation] 発光性マルチブロック両親媒性分子の合成と環境応答特性 (2021)
  • Author(s): 足立惇弥, 佐藤浩平, 金原数
  • Organizer: 日本化学会 第101春季年会
• [Presentation] Transmembrane Anion Transport by Imidazolinium-based Multiblock Amphiphile (2021)
  • Author(s): Miki Mori,Kohei Sato,Toru Ekimoto,Shinichi Okumura,Mitsunori Ikeguchi,Kazuhito Tabata,Hiroyuki Noji,Kazushi Kinbara
  • Organizer: 日本化学会 第101春季年会
• [Presentation] Synthetic Ion Channel with Dual Stimuli-responsiveness (2021)
  • Author(s): Ryo Sasaki,Kohei Sato,Kazuhito Tabata,Hiroyuki Noji,Kazushi Kinbara
  • Organizer: 日本化学会 第101春季年会
• [Presentation] 生体分子を模倣した人工発動分子 の設計に向けて (2020)
  • Author(s): 金原 数
  • Organizer: 「細胞を創る」研究会13.0
  • Invited
• [Presentation] 単分散PEGを利用した熱応答性機能分子の創成 (2020)
  • Author(s): 金原 数
  • Organizer: 第６９回高分子討論会
  • Invited
• [Presentation] Design of stimuli-responsive molecules mimicking dynamic functions of transmembrane proteins (2020)
  • Author(s): Kazushi Kinbara
  • Organizer: SPIE Optics + Photonics 2020
  • Int'l Joint Research / Invited
• [Presentation] 両親媒性ポリサルコシンの合成と物性 (2020)
  • Author(s): 林 虹太 , 佐藤 浩平 , 金原 数
  • Organizer: 第30回バイオ・高分子シンポジウム
  • Invited
• [Presentation] Development of PEG-based Stimuli-Responsive Molecules (2020)
  • Author(s): Kazushi Kinbara
  • Organizer: 2nd International Conference on Materials Design and Applications
  • Int'l Joint Research / Invited
• [Presentation] Fluorinated multiblock amphiphiles that transport ions across lipid bilayers (2020)
  • Author(s): Kohei Sato, Kota Nabeya, Takahiro Muraoka, Norihisa Hoshino, Tomoyuki Akutagawa, Kazushi Kinbara
  • Organizer: ACS Spring 2020 National Meeting & Expo
  • Int'l Joint Research
• [Presentation] Transmembrane ion transport by asymmetric multiblock amphiphiles (2020)
  • Author(s): Ryo Sasaki, Kohei Sato, Kazuhito Tabata, Hiroyuki Noji, Kazushi Kinbara
  • Organizer: ACS Spring 2020 National Meeting & Expo
  • Int'l Joint Research
• [Presentation] Development of amphiphilic linker for protein labeling and polymerization (2020)
  • Author(s): Sanghun Han, Yusuke Aoki, Kohei Sato, Kazushi Kinbara
  • Organizer: 日本化学会第100春季年会
• [Presentation] カチオン部位を導入した交互両親媒性分子による膜間イオン輸送 (2020)
  • Author(s): 森 未妃・佐藤浩平・田端和仁・ 野地博行・金原 数
  • Organizer: 日本化学会第100春季年会
• [Presentation] Rectified Ion Transport by Asymmetric Multiblock Amphiphiles (2019)
  • Author(s): Ryo Sasaki, Kohei Sato, Kazuhito V. Tabata, Hiroyuki Noji, Kazushi Kinbara
  • Organizer: CEMSupra 2019
  • Int'l Joint Research
• [Presentation] 交互両親媒性分子のオリゴマー化 (2019)
  • Author(s): 三栖 花梨, 佐藤 浩平, 金原 数
  • Organizer: 第68回高分子討論会
• [Presentation] 大環状両親媒性 PEG によるタンパク質の凝集抑制 (2019)
  • Author(s): 中川 優大, アダム ヴァヴロ, 佐藤 浩平, 金原 数
  • Organizer: 第68回高分子討論会
• [Presentation] Asymmetric Multiblock Amphiphiles for Transmembrane Ion Transport (2019)
  • Author(s): Ryo Sasaki, Kohei Sato, Kazushi Kinbara
  • Organizer: 第68回高分子討論会
• [Presentation] Transmembrane Ion Transport by Multiblock Arene-Perfluoroarene Macrocycle (2019)
  • Author(s): Kohei Sato, Kota Nabeya, Takahiro Muraoka, Norihisa Hoshino, Tomoyuki Akutagawa, Kazushi Kinbara
  • Organizer: 第68回高分子討論会
• [Presentation] 膜タンパク質を模倣したマルチブロック分子の機能開拓 (2019)
  • Author(s): 金原 数
  • Organizer: 第68回高分子討論会
• [Presentation] 屈曲型交互両親媒性分子の開発 (2019)
  • Author(s): 森 未妃, 佐藤 浩平, 田端 和仁, 野地 博行, 金原 数
  • Organizer: 第13回バイオ関連化学シンポジウム
• [Presentation] 主鎖置換によるタンパク質のサイボーグ化 (2019)
  • Author(s): 青木 祐輔, 宇井 美穂子, 松井 崇, 田中 良和, 村岡 貴博, 佐藤 浩平, 金原 数
  • Organizer: 第68回高分子学会年次大会
• [Presentation] 構造化された大環状ポリアミド誘導体の開発 (2019)
  • Author(s): 玉田 浩之, 佐藤 浩平, 金原 数
  • Organizer: 第68回高分子学会年次大会
• [Presentation] リン酸基を有する双頭型両親媒性分子の開発 (2019)
  • Author(s): 清水 友輔, 佐藤 浩平, 金原 数
  • Organizer: 第68回高分子学会年次大会
• [Presentation] Design of Engineered PEGs for Biomaterial Developments (2019)
  • Author(s): Kazushi Kinbara
  • Organizer: 10th International Conference on Materials for Advanced Technologies
  • Int'l Joint Research / Invited
• [Presentation] Development of Amphiphilic Multiblock Molecule Bearing Cationic Moiety (2019)
  • Author(s): Miki Mori, Kohei Sato, Kazushi Kinbara
  • Organizer: 10th International Conference on Materials for Advanced Technologies
  • Int'l Joint Research
• [Presentation] Synthetic Multiblock Molecules Mimicking Structure and Function of Membrane Proteins (2019)
  • Author(s): Kazushi Kinbara
  • Organizer: 2nd International Conference on Molecular Systems Engineering
  • Int'l Joint Research
• [Presentation] Design of synthetic chiral receptor molecules inspired by structure and function of membrane proteins (2019)
  • Author(s): Kazushi Kinbara, Takahiro Muraoka, Daiki Noguchi, Takahiro Endo
  • Organizer: Chirality2019
  • Int'l Joint Research
• [Presentation] Design of PEG-Based Functional Molecules for Biorelated Applications (2019)
  • Author(s): Kazushi Kinbara
  • Organizer: Japan-BIOCEV Symposium
  • Int'l Joint Research / Invited
• [Presentation] Development of PEG-based Stimuli-Responsive Molecules (2019)
  • Author(s): Kauzhi Kinbara
  • Organizer: 2nd International Conference on Materials Design and Applications
  • Int'l Joint Research / Invited
• [Presentation] Protein Cyborgization by Main Chain Substitution (2019)
  • Author(s): AOKI, Yusuke; UI, Mihoko; MATSUI, Takashi;TANAKA, Yoshikazu; MURAOKA, Takahiro; SATO, Kohei; KINBARA, Kazushi
  • Organizer: 日本化学会第99春季年会
• [Presentation] Development of Multiblock Amphiphilic Molecules bearing Dihy- droimidazolium Ion (2019)
  • Author(s): MORI, Miki; SATO, Kohei; KINBARA, Kazushi
  • Organizer: 日本化学会第99春季年会
• [Presentation] Development of multiblock arene-perfluoroarene macrocycle (2019)
  • Author(s): SATO, Kohei; NABEYA, Kota; MURAOKA, Takahiro; HOSHINO, Norihisa; AKUTAGAWA, Tomoyuki; KINBARA, Kazushi
  • Organizer: 日本化学会第99春季年会
• [Presentation] Synthesis and Properties of Multiblock Amphiphilic Ligand Molecules (2018)
  • Author(s): Miki Mori, Kohei Sato, Kazushi Kinbara
  • Organizer: The 12th SPSJ International Polymer Conference (IPC2018)
  • Int'l Joint Research
• [Presentation] Macrocyclic Multiblock Amphiphilic PEGs for Biorelated Applications (2018)
  • Author(s): Yudai Nakagawa, Kohei Sato, Adam M. Wawro, Kazushi Kinbara
  • Organizer: The 12th SPSJ International Polymer Conference (IPC2018)
  • Int'l Joint Research
• [Presentation] Synthetic mimics of transmembrane proteins (2018)
  • Author(s): Kazushi Kinbara
  • Organizer: The 79th Okazaki Conference
  • Int'l Joint Research / Invited
• [Presentation] Approach to molecular engines: Design of stimuli-responsive molecules mimicking dynamic functions of transmembrane proteins (2018)
  • Author(s): Kazushi Kinbara
  • Organizer: Hokkaido-Strasbourg Symposium Biotic and Abiotic Molecular Machines and Motors
  • Int'l Joint Research / Invited
• [Presentation] Design of stimuli-responsive molecules mimicking dynamic functions of transmembrane proteins (2018)
  • Author(s): Kazushi Kinbara
  • Organizer: Tokyo Tech NCCR Molecular Systems Engineering Joint Symposium
  • Int'l Joint Research / Invited
• [Presentation] 膜タンパク質を模倣した人工分子の設計と機能開拓 (2018)
  • Author(s): 金原 数
  • Organizer: 日本生体エネルギー研究会 第44回討論会
  • Invited
• [Presentation] タンパク質構造に学ぶ合成分子機械の設計 (2018)
  • Author(s): 金原 数
  • Organizer: 第15回原子・分子・光科学（AMO）討論会
  • Invited
• [Presentation] 大環状マルチブロック両親媒性PEGの開発と機能開拓 (2018)
  • Author(s): 中川優大・佐藤浩平・Adam M. Wawro・金原 数
  • Organizer: 第8回CSJ化学フェスタ
• [Presentation] リン酸エステル含有交互両親媒性分子の合成と物性評価 (2018)
  • Author(s): 三栖花梨・佐藤浩平・金原 数
  • Organizer: 第8回CSJ化学フェスタ
• [Presentation] 交互両親媒性リガンド分子の合成と物性 (2018)
  • Author(s): 森 水紀・佐藤浩平・金原 数
  • Organizer: 第8回CSJ化学フェスタ
• [Presentation] リガンド型膜貫通分子の構築 (2018)
  • Author(s): 園部宏樹・村岡貴博・金原数
  • Organizer: 第12回バイオ関連化学シンポジウム
• [Remarks] 発動分子科学
  • URL: http://www.molecular-engine.bio.titech.ac.jp/
• [Remarks] 発動分子科学 - エネルギー変換が拓く自律的機能の設計
  • URL: http://www.molecular-engine.bio.titech.ac.jp
• [Remarks] 発動分子科学
  • URL: http://www.molecular-engine.bio.titech.ac.jp
• [Funded Workshop] The 2nd International Workshop on Molecular Engine (2022)
• [Funded Workshop] The 1st International Symposium on Molecular Engine (2020)
• [Funded Workshop] 10th International Conference on Materials for Advanced Technologies (2019)