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Molecular Engine: Design of Autonomous Functions through Energy Conversion (Administration)

Administrative Group

Project AreaMolecular Engine: Design of Autonomous Functions through Energy Conversion
Project/Area Number 18H05418
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionTokyo Institute of Technology

Principal Investigator

Kazushi Kinbara  東京工業大学, 生命理工学院, 教授 (30282578)

Co-Investigator(Kenkyū-buntansha) 上野 隆史  東京工業大学, 生命理工学院, 教授 (70332179)
Project Period (FY) 2018-06-29 – 2023-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥105,170,000 (Direct Cost: ¥80,900,000、Indirect Cost: ¥24,270,000)
Fiscal Year 2022: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2021: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2019: ¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2018: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
Keywords分子機械 / エネルギー変換 / 集団運動 / 分子モーター / 超分子化学 / アクティブマター / ハイブリッド分子 / 分子集合体 / 発動分子 / ソフトロボット / 分子エンジン / 人工分子機械 / 生体分子機械
Outline of Final Research Achievements

In order to support establishing the academic principles of molecular engine, group meetings, research meetings, and symposia were held. Also, collaborative researches were promoted through joint research proposals and technical support. In addition, ME-Hub was established as a support organization to promote collaborative research in this area, and actively supported interdisciplinary research. The ME-Hub provided advice, technical support, and information on the construction of molecular engines, and supported collaboration among researchers in different fields. In parallel with this, support for international activities was provided and outreach activities were conducted. In addition, with the cooperation of companies, ME-Innov was established to encourage industry-government-academia collaboration in molecular engines.

Academic Significance and Societal Importance of the Research Achievements

「発動分子科学」において得られた研究成果は,エネルギー変換を実現する分子システムに対する理解を飛躍的に深化させるものである。さらには,これまでに想定されてこなかった,生体分子ー合成分子ハイブリッド型分子により革新的な機能を実現できる可能性を示すことができた。分子レベルでのエネルギー変換技術は,将来的に社会の省エネルギー化につながる極めて重要な研究課題であり,本研究における成果は,これを支援する上で必須の活動を主体としており,その意義は極めて大きかったといえる。

Report

(6 results)
  • 2023 Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (109 results)

All 2023 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (12 results) Journal Article (22 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 22 results,  Open Access: 6 results) Presentation (69 results) (of which Int'l Joint Research: 19 results,  Invited: 15 results) Remarks (3 results) Funded Workshop (3 results)

  • [Int'l Joint Research] Bordeaux大(フランス)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Manchester大(英国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Bristol大学(英国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] IECB(フランス)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] IECB(フランス)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Bristol大学(英国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] ボルド-大学(フランス)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] アイルランド国立大学(アイルランド)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] 精華大学(中国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] マサチューセッツ工科大学(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] ボルドー大学/CNRS/IECB(フランス)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] アイルランド国立大学(アイルランド)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Sensitivity Tuning of 9,10-Di(piperazinyl)anthracene Derivatives for Amphiphilic Assemblies by pH and Side-chain Modification with Monodisperse Oligo(ethylene glycol)s2023

    • Author(s)
      Adachi Junya、Kinbara Kazushi
    • Journal Title

      Chemistry Letters

      Volume: 52 Issue: 3 Pages: 218-221

    • DOI

      10.1246/cl.230025

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection2023

    • Author(s)
      Adachi Junya、Oda Haruka、Fukushima Toshiaki、Lestari Beni、Kimura Hiroshi、Sugai Hiroka、Shiraki Kentaro、Hamaguchi Rei、Sato Kohei、Kinbara Kazushi
    • Journal Title

      Analytical Chemistry

      Volume: 95 Issue: 12 Pages: 5196-5204

    • DOI

      10.1021/acs.analchem.2c04133

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Synthesis and properties of multiblock amphiphilic cyclophanes with chiral aromatic units2023

    • Author(s)
      Matsuda Ryoto、Otake Haruki、Sato Kohei、Kinbara Kazushi
    • Journal Title

      Polymer Journal

      Volume: 55 Issue: 11 Pages: 1225-1229

    • DOI

      10.1038/s41428-023-00812-6

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Supramolecular Mechanosensitive Potassium Channel Formed by Fluorinated Amphiphilic Cyclophane2022

    • Author(s)
      Sato Kohei、Sasaki Ryo、Matsuda Ryoto、Nakagawa Mayuko、Ekimoto Toru、Yamane Tsutomu、Ikeguchi Mitsunori、Tabata Kazuhito V.、Noji Hiroyuki、Kinbara Kazushi
    • Journal Title

      Journal of the American Chemical Society

      Volume: 144 Issue: 26 Pages: 11802-11809

    • DOI

      10.1021/jacs.2c04118

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiblock Amphiphilic Triptycene toward Bioinspired Molecular Rotor in Membrane2022

    • Author(s)
      Yospanya Wijak、Sato Kohei、Kinbara Kazushi
    • Journal Title

      Chemistry Letters

      Volume: 51 Issue: 10 Pages: 1026-1028

    • DOI

      10.1246/cl.220360

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Calcium-induced reversible assembly of phosphorylated amphiphile within lipid bilayer membranes2021

    • Author(s)
      Shimizu Yusuke、Sato Kohei、Kinbara Kazushi
    • Journal Title

      Chemical Communications

      Volume: 57 Issue: 34 Pages: 4106-4109

    • DOI

      10.1039/d1cc01111a

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Properties of Imidazolinium-containing Multiblock Amphiphile in Lipid Bilayer Membranes2021

    • Author(s)
      Mori Miki Mori, Kinbara Kazushi
    • Journal Title

      Journal of Photopolymer Science and Technology

      Volume: 34 Pages: 161-165

    • NAID

      130008119674

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Supramolecular Transmembrane Ion Channels Formed by Multiblock Amphiphiles2021

    • Author(s)
      Sato Kohei、Muraoka Takahiro、Kinbara Kazushi
    • Journal Title

      Accounts of Chemical Research

      Volume: 54 Issue: 19 Pages: 3700-3709

    • DOI

      10.1021/acs.accounts.1c00397

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemical Molecular Machines and Robots2021

    • Author(s)
      Kinbara Kazushi
    • Journal Title

      Encyclopedia of Robotics

      Volume: 1 Pages: 1-13

    • DOI

      10.1007/978-3-642-41610-1_211-1

    • ISBN
      9783642416101
    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthetic Ion Channel Formed by Multiblock Amphiphile with Anisotropic Dual-Stimuli-Responsiveness2021

    • Author(s)
      Sasaki Ryo、Sato Kohei、Tabata Kazuhito V.、Noji Hiroyuki、Kinbara Kazushi
    • Journal Title

      Journal of the American Chemical Society

      Volume: 143 Issue: 3 Pages: 1348-1355

    • DOI

      10.1021/jacs.0c09470

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imidazolinium‐based Multiblock Amphiphile as Transmembrane Anion Transporter2020

    • Author(s)
      Mori Miki、Sato Kohei、Ekimoto Toru、Okumura Shinichi、Ikeguchi Mitsunori、Tabata Kazuhito V.、Noji Hiroyuki、Kinbara Kazushi
    • Journal Title

      Chemistry - An Asian Journal

      Volume: 16 Issue: 2 Pages: 147-157

    • DOI

      10.1002/asia.202001106

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thermo-driven self-assembly of a PEG-containing amphiphile in a bilayer membrane2020

    • Author(s)
      Li Rui、Muraoka Takahiro、Kinbara Kazushi
    • Journal Title

      RSC Advances

      Volume: 10 Issue: 43 Pages: 25758-25762

    • DOI

      10.1039/d0ra03920a

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A synthetic ion channel with anisotropic ligand response2020

    • Author(s)
      Muraoka Takahiro, Noguchi Daiki, Kasai Rinshi, Sato Kohei, Sasaki Ryo, Tabata Kazuhito, Ekimoto Toru, Ikeguchi Mitsunori, Kamagata Kiyoto, Hoshino Norihisa, Noji Hiroyuki, Akutagawa Tomoyuki, Ichimura Kazuaki, Kinbara Kazushi
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 2924-2924

    • DOI

      10.1038/s41467-020-16770-z

    • NAID

      120006878529

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reversible formation of multiple stimuli-responsive polymeric materials through processing control of trifunctional amphiphilic molecules2020

    • Author(s)
      Muraoka Takahiro、Honda Hidetaka、Nabeya Kota、Kinbara Kazushi
    • Journal Title

      Chemical Communications

      Volume: 56 Issue: 57 Pages: 7881-7884

    • DOI

      10.1039/d0cc02716b

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] タンパク質を模倣した人工発動分子の創製に向けて -膜タンパク質を模倣した合成化学的アプローチ-,2020

    • Author(s)
      金原 数
    • Journal Title

      化学と工業

      Volume: 73 Pages: 457-459

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aromatic Fluorination of Multiblock Amphiphile Enhances Its Incorporation into Lipid Bilayer Membranes2020

    • Author(s)
      Sasaki Ryo, Sato Kohei, Kinbara Kazushi
    • Journal Title

      ChemistryOpen

      Volume: 9 Issue: 3 Pages: 301-303

    • DOI

      10.1002/open.201900374

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] New Modified Deoxythymine with Dibranched Tetraethylene Glycol Stabilizes G-quadruplex Structures2020

    • Author(s)
      H. Tateishi-Karimata, T. Ohyama, T. Muraoka, S. Tanaka, K. Kinbara, and N. Sugimoto
    • Journal Title

      Molecules

      Volume: 25 Issue: 3 Pages: 705-705

    • DOI

      10.3390/molecules25030705

    • NAID

      120006811187

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Introduction: Molecular Motors2020

    • Author(s)
      Iino Ryota、Kinbara Kazushi、Bryant Zev
    • Journal Title

      Chemical Reviews

      Volume: 120 Issue: 1 Pages: 1-4

    • DOI

      10.1021/acs.chemrev.9b00819

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Session 2SDA―Nonequilibrium energetics of biological molecular machines2020

    • Author(s)
      Toyabe Shoichi, Li Chun-Biu, Kinbara Kazushi
    • Journal Title

      Biophysical Reviews

      Volume: 12 Issue: 2 Pages: 273-274

    • DOI

      10.1007/s12551-020-00634-3

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 1.Development of an Engineered Photoactive Yellow Protein as a Cross-Linking Junction for Construction of Photoresponsive Protein-Polymer Conjugates2019

    • Author(s)
      Ui, Mihoko; Miyauchi, Yusuke; Inoue, Masataka; Murakami, Makoto; Araki, Yasuyuki; Wada, Takehiko; Kinbara, Kazushi
    • Journal Title

      ChemPhotoChem

      Volume: 3 Issue: 6 Pages: 356-360

    • DOI

      10.1002/cptc.201900024

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Heat-Triggered Crystallization of Liquid Crystalline Macrocycles Allowing for Conductance Switching through Hysteretic Thermal Phase Transitions2018

    • Author(s)
      Muraoka Takahiro、Shima Tatsuya、Kajitani Takashi、Hoshino Norihisa、Morvan Estelle、Grelard Axelle、Dufourc Erick J.、Fukushima Takanori、Akutagawa Tomoyuki、Nabeya Kota、Kinbara Kazushi
    • Journal Title

      Chemistry - An Asian Journal

      Volume: 14 Issue: 1 Pages: 141-148

    • DOI

      10.1002/asia.201801372

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Localization of transmembrane multiblock amphiphilic molecules in phase-separated vesicles2018

    • Author(s)
      Kazushi Kinbara, Kaori Umetsu, Hiroki Sonobe, Takahiro Muraoka, Naofumi Shimokawa, Masahiro Takagi
    • Journal Title

      Faraday Discussions

      Volume: 印刷中 Pages: 315-328

    • DOI

      10.1039/c8fd00022k

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Presentation] Development of Anthracene-Based Fluorescent Probes for Application in Cellular Systems2022

    • Author(s)
      Junya Adachi, Toshiaki Fukushima, Haruka Oda, Hiroka Sugai, Kohei Sato, Hiroshi Kimura, Kazushi Kinbara
    • Organizer
      The 19th International Symposium on Novel Aromatic Compounds
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Multiblock Amphiphilic Molecules as Synthetic Mimics of Transmembrane Channel-forming Proteins2022

    • Author(s)
      Kazushi Kinbara
    • Organizer
      10th Asian Biological Inorganic Chemistry Conference (AsBIC10)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Design of Multiblock Amphiphilic Molecules for Ion Transportation Across Membranes2022

    • Author(s)
      Kazushi Kinbara
    • Organizer
      4th International Conference on Emerging Advanced Nanomaterials (ICEAN 2022)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 非TICT型粘度応答性蛍光プローブの開発と生細胞イメージングへの適用2022

    • Author(s)
      足立惇弥, 福嶋 俊明, 小田 春佳, 菅井 祥加, 佐藤 浩平, 木村 宏, 金原 数
    • Organizer
      2022年光化学討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Development of cyclic oligo(ethylene glycol) for suppression of amyloid protein fibrillation,2022

    • Author(s)
      Thirasara Sammani, Wijak Yospanya, Adam M. Wawro, Kohei Sato, Kazushi Kinbara
    • Organizer
      第71回高分子討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Amphiphilic oligo(ethylene glycol)s as protein stabilizers: effect of structure2022

    • Author(s)
      Wijak Yospanya, Thirasara Sammani, Kohei Sato, Adam M. Wawro, Kazushi Kinbara
    • Organizer
      第71回高分子討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Development of multiblock amphiphilic cyclophanes and their functions within lipid bilayer membranes2022

    • Author(s)
      Ryoto Matsuda, Kohei Sato, Kazushi Kinbara
    • Organizer
      第71回高分子討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Thermal diffusivity of structured poly(ethylene glycols)2022

    • Author(s)
      Mitsuhiro Matsumoto, Meguya Ryu, Kohei Sato, Anna Ishikawa, Takashi Kajitani, Yoshihisa Sei, Nobutaka Honma, Katsuhiko Nakajima, Junzo Ukai, Junko Morikawa, Kazushi Kinbara
    • Organizer
      第71回高分子討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 非対称構造を有する膜貫通型両親媒性分子の開発2022

    • Author(s)
      大熊 葵, 佐藤 浩平, 金原 数
    • Organizer
      第71回高分子学会年次大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 構造化大環状ポリアミドによる超分子構造体の構築2022

    • Author(s)
      中村 彰吾, 玉田 浩之, 佐藤 浩平, 金原 数
    • Organizer
      第71回高分子学会年次大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 水中における過渡的な両親媒性分子生成サイクルの構築2022

    • Author(s)
      中川 優芽, 森 未妃, 佐藤 浩平, 金原 数
    • Organizer
      第71回高分子学会年次大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Hybrid kinesin-1 dimer conjugated with synthetic PEG linker shows processive and fast motion with robust hand-over-hand mechanism2022

    • Author(s)
      Jakia Jannat Keya, Akasit Visootsat, Kimitoshi Takeda, Akihiro Otomo, Wijak Yospanya, Sanghun Han, Kazushi Kinbara, Ryota Iino
    • Organizer
      第60回日本生物物理学会年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] QM/MM simulations of cyclic artificial ion channel in membrane-water system2022

    • Author(s)
      Mayuko Nakagawa, Toru Ekimoto, Tsutomu Yamane, Kohei Sato, Kazushi Kinbara, Mitsunori Ikeguchi
    • Organizer
      第60回日本生物物理学会年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] フッ素化人工チャネルによる膜間物質輸送2022

    • Author(s)
      佐藤 浩平, 金原 数
    • Organizer
      第16回バイオ関連化学シンポジウム
    • Related Report
      2022 Annual Research Report
  • [Presentation] Development of functional anthracene-based multiblock fluorophore for visualization of biological environment2022

    • Author(s)
      Junya Adachi , Kohei Sato , Kazushi Kinbara
    • Organizer
      日本化学会 第102春季年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 両親媒性分子の過渡的な生成に基づく化学反応サイクルの構築2022

    • Author(s)
      中川 優芽 , 森 未妃 , 佐藤 浩平 , 金原 数
    • Organizer
      日本化学会 第102春季年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 構造化大環状ポリアミドの自己集合2022

    • Author(s)
      中村 彰吾 , 玉田 浩之 , 佐藤 浩平 , 金原 数
    • Organizer
      日本化学会 第102春季年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] An artificial ion channel studied by all-atom molecular dynamics simulations2021

    • Author(s)
      中川真由子 , 浴本亨 , 山根努 , 村岡貴博 , 佐藤浩平 , 金原数 , 池口満徳
    • Organizer
      第21回日本蛋白質科学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 発光性マルチブロック両親媒性分子の合成と発光特性2021

    • Author(s)
      足立 惇弥 , 佐藤 浩平 , 金原 数
    • Organizer
      発動分子科学研究会
    • Related Report
      2021 Annual Research Report
  • [Presentation] フッ素化交互両親媒性分子による超分子イオンチャネルの構築2021

    • Author(s)
      佐藤 浩平 , 佐々木 崚 , 田端 和仁 , 野地 博行 , 金原 数
    • Organizer
      第 31 回バイオ・高分子シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] Development of cyclic oligo(ethylene glycol) for suppression of amyloid protein fibrillation2021

    • Author(s)
      Thirasara Sammani , Wijak Yospanya , Adam M. Wawro , Kohei Sato , Kazushi Kinbara
    • Organizer
      発動分子科学研究会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Transmembrane Ion Transport by Fluorinated Amphiphilic Cyclophanes2021

    • Author(s)
      Kohei Sato , Ryo Sasaki , Ryoto Matsuda , Kazuhito V. Tabata , Hiroyuki Noji , Kazushi Kinbara
    • Organizer
      発動分子科学研究会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 膜タンパク質を模倣した交互両親媒性分子の階層的集合化と機能発現2021

    • Author(s)
      佐藤浩平 , 佐々木崚 , 田端和仁 , 野地博行 , 金原数
    • Organizer
      第70回高分子討論会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Fluorinated multiblock amphiphiles and their transmembrane ion transport properties2021

    • Author(s)
      Kohei Sato , Ryo Sasaki , Kazuhito Tabata , Hiroyuki Noji , Kazushi Kinbara
    • Organizer
      Pacifichem 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] Development of chiral multiblock amphiphiles and their functions within lipid bilayer membranes2021

    • Author(s)
      Ryoto Matsuda , Kohei Sato , Ryo Sasaki , Kazuhito Tabata , Hiroyuki Noji , Kazushi Kinbara
    • Organizer
      Pacifichem 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] Multiblock amphiphile bearing imidazolinium as transmembrane anion transporter2021

    • Author(s)
      Miki Mori , Kohei Sato , Toru Ekimoto , Shinichi Okumura , Mitsunori Ikeguchi , Kazuhito Tabata , Hiroyuki Noji , Kazushi Kinbara
    • Organizer
      Pacifichem 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] Synthesis of anthracene-based multiblock amphiphile and its stimuli-responsiveness within phospholipid membranes2021

    • Author(s)
      Junya Adachi , Kohei Sato , Kazushi Kinbara
    • Organizer
      Pacifichem 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] 発光性マルチブロック両親媒性分子の合成と環境応答特性2021

    • Author(s)
      足立惇弥, 佐藤浩平, 金原数
    • Organizer
      日本化学会 第101春季年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Transmembrane Anion Transport by Imidazolinium-based Multiblock Amphiphile2021

    • Author(s)
      Miki Mori,Kohei Sato,Toru Ekimoto,Shinichi Okumura,Mitsunori Ikeguchi,Kazuhito Tabata,Hiroyuki Noji,Kazushi Kinbara
    • Organizer
      日本化学会 第101春季年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Synthetic Ion Channel with Dual Stimuli-responsiveness2021

    • Author(s)
      Ryo Sasaki,Kohei Sato,Kazuhito Tabata,Hiroyuki Noji,Kazushi Kinbara
    • Organizer
      日本化学会 第101春季年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 生体分子を模倣した人工発動分子 の設計に向けて2020

    • Author(s)
      金原 数
    • Organizer
      「細胞を創る」研究会13.0
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 単分散PEGを利用した熱応答性機能分子の創成2020

    • Author(s)
      金原 数
    • Organizer
      第69回高分子討論会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Design of stimuli-responsive molecules mimicking dynamic functions of transmembrane proteins2020

    • Author(s)
      Kazushi Kinbara
    • Organizer
      SPIE Optics + Photonics 2020
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 両親媒性ポリサルコシンの合成と物性2020

    • Author(s)
      林 虹太 , 佐藤 浩平 , 金原 数
    • Organizer
      第30回バイオ・高分子シンポジウム
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Development of PEG-based Stimuli-Responsive Molecules2020

    • Author(s)
      Kazushi Kinbara
    • Organizer
      2nd International Conference on Materials Design and Applications
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Fluorinated multiblock amphiphiles that transport ions across lipid bilayers2020

    • Author(s)
      Kohei Sato, Kota Nabeya, Takahiro Muraoka, Norihisa Hoshino, Tomoyuki Akutagawa, Kazushi Kinbara
    • Organizer
      ACS Spring 2020 National Meeting & Expo
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Transmembrane ion transport by asymmetric multiblock amphiphiles2020

    • Author(s)
      Ryo Sasaki, Kohei Sato, Kazuhito Tabata, Hiroyuki Noji, Kazushi Kinbara
    • Organizer
      ACS Spring 2020 National Meeting & Expo
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of amphiphilic linker for protein labeling and polymerization2020

    • Author(s)
      Sanghun Han, Yusuke Aoki, Kohei Sato, Kazushi Kinbara
    • Organizer
      日本化学会第100春季年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] カチオン部位を導入した交互両親媒性分子による膜間イオン輸送2020

    • Author(s)
      森 未妃・佐藤浩平・田端和仁・ 野地博行・金原 数
    • Organizer
      日本化学会第100春季年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Rectified Ion Transport by Asymmetric Multiblock Amphiphiles2019

    • Author(s)
      Ryo Sasaki, Kohei Sato, Kazuhito V. Tabata, Hiroyuki Noji, Kazushi Kinbara
    • Organizer
      CEMSupra 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 交互両親媒性分子のオリゴマー化2019

    • Author(s)
      三栖 花梨, 佐藤 浩平, 金原 数
    • Organizer
      第68回高分子討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 大環状両親媒性 PEG によるタンパク質の凝集抑制2019

    • Author(s)
      中川 優大, アダム ヴァヴロ, 佐藤 浩平, 金原 数
    • Organizer
      第68回高分子討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Asymmetric Multiblock Amphiphiles for Transmembrane Ion Transport2019

    • Author(s)
      Ryo Sasaki, Kohei Sato, Kazushi Kinbara
    • Organizer
      第68回高分子討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Transmembrane Ion Transport by Multiblock Arene-Perfluoroarene Macrocycle2019

    • Author(s)
      Kohei Sato, Kota Nabeya, Takahiro Muraoka, Norihisa Hoshino, Tomoyuki Akutagawa, Kazushi Kinbara
    • Organizer
      第68回高分子討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 膜タンパク質を模倣したマルチブロック分子の機能開拓2019

    • Author(s)
      金原 数
    • Organizer
      第68回高分子討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 屈曲型交互両親媒性分子の開発2019

    • Author(s)
      森 未妃, 佐藤 浩平, 田端 和仁, 野地 博行, 金原 数
    • Organizer
      第13回バイオ関連化学シンポジウム
    • Related Report
      2019 Annual Research Report
  • [Presentation] 主鎖置換によるタンパク質のサイボーグ化2019

    • Author(s)
      青木 祐輔, 宇井 美穂子, 松井 崇, 田中 良和, 村岡 貴博, 佐藤 浩平, 金原 数
    • Organizer
      第68回高分子学会年次大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 構造化された大環状ポリアミド誘導体の開発2019

    • Author(s)
      玉田 浩之, 佐藤 浩平, 金原 数
    • Organizer
      第68回高分子学会年次大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] リン酸基を有する双頭型両親媒性分子の開発2019

    • Author(s)
      清水 友輔, 佐藤 浩平, 金原 数
    • Organizer
      第68回高分子学会年次大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Design of Engineered PEGs for Biomaterial Developments2019

    • Author(s)
      Kazushi Kinbara
    • Organizer
      10th International Conference on Materials for Advanced Technologies
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of Amphiphilic Multiblock Molecule Bearing Cationic Moiety2019

    • Author(s)
      Miki Mori, Kohei Sato, Kazushi Kinbara
    • Organizer
      10th International Conference on Materials for Advanced Technologies
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synthetic Multiblock Molecules Mimicking Structure and Function of Membrane Proteins2019

    • Author(s)
      Kazushi Kinbara
    • Organizer
      2nd International Conference on Molecular Systems Engineering
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Design of synthetic chiral receptor molecules inspired by structure and function of membrane proteins2019

    • Author(s)
      Kazushi Kinbara, Takahiro Muraoka, Daiki Noguchi, Takahiro Endo
    • Organizer
      Chirality2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Design of PEG-Based Functional Molecules for Biorelated Applications2019

    • Author(s)
      Kazushi Kinbara
    • Organizer
      Japan-BIOCEV Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of PEG-based Stimuli-Responsive Molecules2019

    • Author(s)
      Kauzhi Kinbara
    • Organizer
      2nd International Conference on Materials Design and Applications
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Protein Cyborgization by Main Chain Substitution2019

    • Author(s)
      AOKI, Yusuke; UI, Mihoko; MATSUI, Takashi;TANAKA, Yoshikazu; MURAOKA, Takahiro; SATO, Kohei; KINBARA, Kazushi
    • Organizer
      日本化学会第99春季年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Development of Multiblock Amphiphilic Molecules bearing Dihy- droimidazolium Ion2019

    • Author(s)
      MORI, Miki; SATO, Kohei; KINBARA, Kazushi
    • Organizer
      日本化学会第99春季年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Development of multiblock arene-perfluoroarene macrocycle2019

    • Author(s)
      SATO, Kohei; NABEYA, Kota; MURAOKA, Takahiro; HOSHINO, Norihisa; AKUTAGAWA, Tomoyuki; KINBARA, Kazushi
    • Organizer
      日本化学会第99春季年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Synthesis and Properties of Multiblock Amphiphilic Ligand Molecules2018

    • Author(s)
      Miki Mori, Kohei Sato, Kazushi Kinbara
    • Organizer
      The 12th SPSJ International Polymer Conference (IPC2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Macrocyclic Multiblock Amphiphilic PEGs for Biorelated Applications2018

    • Author(s)
      Yudai Nakagawa, Kohei Sato, Adam M. Wawro, Kazushi Kinbara
    • Organizer
      The 12th SPSJ International Polymer Conference (IPC2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synthetic mimics of transmembrane proteins2018

    • Author(s)
      Kazushi Kinbara
    • Organizer
      The 79th Okazaki Conference
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Approach to molecular engines: Design of stimuli-responsive molecules mimicking dynamic functions of transmembrane proteins2018

    • Author(s)
      Kazushi Kinbara
    • Organizer
      Hokkaido-Strasbourg Symposium Biotic and Abiotic Molecular Machines and Motors
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Design of stimuli-responsive molecules mimicking dynamic functions of transmembrane proteins2018

    • Author(s)
      Kazushi Kinbara
    • Organizer
      Tokyo Tech NCCR Molecular Systems Engineering Joint Symposium
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 膜タンパク質を模倣した人工分子の設計と機能開拓2018

    • Author(s)
      金原 数
    • Organizer
      日本生体エネルギー研究会 第44回討論会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] タンパク質構造に学ぶ合成分子機械の設計2018

    • Author(s)
      金原 数
    • Organizer
      第15回原子・分子・光科学(AMO)討論会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 大環状マルチブロック両親媒性PEGの開発と機能開拓2018

    • Author(s)
      中川優大・佐藤浩平・Adam M. Wawro・金原 数
    • Organizer
      第8回CSJ化学フェスタ
    • Related Report
      2018 Annual Research Report
  • [Presentation] リン酸エステル含有交互両親媒性分子の合成と物性評価2018

    • Author(s)
      三栖花梨・佐藤浩平・金原 数
    • Organizer
      第8回CSJ化学フェスタ
    • Related Report
      2018 Annual Research Report
  • [Presentation] 交互両親媒性リガンド分子の合成と物性2018

    • Author(s)
      森 水紀・佐藤浩平・金原 数
    • Organizer
      第8回CSJ化学フェスタ
    • Related Report
      2018 Annual Research Report
  • [Presentation] リガンド型膜貫通分子の構築2018

    • Author(s)
      園部宏樹・村岡貴博・金原数
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Remarks] 発動分子科学

    • URL

      http://www.molecular-engine.bio.titech.ac.jp/

    • Related Report
      2022 Annual Research Report 2021 Annual Research Report
  • [Remarks] 発動分子科学 - エネルギー変換が拓く自律的機能の設計

    • URL

      http://www.molecular-engine.bio.titech.ac.jp

    • Related Report
      2020 Annual Research Report
  • [Remarks] 発動分子科学

    • URL

      http://www.molecular-engine.bio.titech.ac.jp

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] The 2nd International Workshop on Molecular Engine2022

    • Related Report
      2021 Annual Research Report
  • [Funded Workshop] The 1st International Symposium on Molecular Engine2020

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] 10th International Conference on Materials for Advanced Technologies2019

    • Related Report
      2019 Annual Research Report

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Published: 2018-07-20   Modified: 2025-01-30  

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