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Multicellular Neurobiocomputing (Administrative Group)

Administrative Group

Project AreaMulticellular neurobiocomputing
Project/Area Number 21H05162
Research Category

Grant-in-Aid for Transformative Research Areas (B)

Allocation TypeSingle-year Grants
Review Section Transformative Research Areas, Section (IV)
Research InstitutionTohoku University

Principal Investigator

Yamamoto Hideaki  東北大学, 電気通信研究所, 准教授 (10552036)

Co-Investigator(Kenkyū-buntansha) 香取 勇一  公立はこだて未来大学, システム情報科学部, 教授 (20557607)
松井 鉄平  同志社大学, 脳科学研究科, 教授 (10725948)
正水 芳人  同志社大学, 脳科学研究科, 教授 (90608530)
Project Period (FY) 2021-08-23 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Fiscal Year 2023: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2022: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2021: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords多細胞バイオ計算 / 予測符号化 / リザバーコンピューティング / 培養神経回路 / 大脳皮質 / バイオイメージング / カルシウムイメージング / 自発活動
Outline of Research at the Start

総括班は,領域代表者・計画研究代表者・領域アドバイザーより構成される.領域代表者と計画研究代表者は総括班の一員として,領域の運営方針の策定,各計画班間の連携の効率化,研究成果の発信を行う.領域アドバイザーからは,研究計画を確実に遂行するために領域の計画や方針に関する評価・助言を受ける.

Outline of Final Research Achievements

This Research Area aimed to establish a new platform for interdisciplinary collaboration that transcends the boundaries of academic disciplines in order to understand and model the mechanism by which the brain (especially the mammalian neocortex) realizes information processing using multicellular networks. We promoted interdisciplinary research that crosses the boundaries of life science, engineering, and information science, and succeeded in: (1) proposing a bio-plausible model that mimics information processing in the neocortex, (2) showing a proof-of-concept experiment for reservoir computing using cultured neuronal networks, (3) clarifying a self-organization principle of the visual cortical circuitry in mice, and (4) constructing a novel setup to study the self-repair process in the model animal brain after a localized injury.

Academic Significance and Societal Importance of the Research Achievements

本領域活動により,生物の脳を構成する多細胞ネットワークを対象として,モデル動物を使った研究(in vivo)・培養細胞を使った研究(in vitro)・数理モデルを使った研究(in silico)の有機的な連携体制が構築できた.このような連携によって脳神経回路の計算機構の理解が深まることは学術的に重要なことはもちろんのこと,現代のAIや脳型ハードウェアが直面する電力効率や学習効率などの課題の解決にも結びつく可能性がある.

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • Research Products

    (24 results)

All 2024 2023 2022 Other

All Int'l Joint Research (11 results) Presentation (4 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results) Remarks (6 results) Funded Workshop (3 results)

  • [Int'l Joint Research] ミネソタ大学(米国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] ボルドー大学(フランス)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] カルガリー大学(カナダ)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] バルセロナ大学(スペイン)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] ミネソタ大学(米国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] バルセロナ大学(スペイン)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Cortical Labs(オーストラリア)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] ミネソタ大学(米国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] カルガリー大学(カナダ)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] ボルドー大学(フランス)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] バルセロナ大学(スペイン)

    • Related Report
      2021 Annual Research Report
  • [Presentation] "Multicellular Neurobiocomputing" and beyond2024

    • Author(s)
      H. Yamamoto, Y. Katori, T. Matsui, Y. Masamizu
    • Organizer
      The 12th RIEC International Symposium on Brain Functions and Brain Computer
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 「多細胞バイオ計算」領域のご紹介(シンポジウム:若手が切り開く脳科学の未来)2023

    • Author(s)
      山本 英明
    • Organizer
      第33回日本神経回路学会全国大会
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 趣旨説明(シンポジウム「次世代ICTと未来医療を支える神経科学・神経工学・脳型コンピューティング」)2022

    • Author(s)
      山本 英明
    • Organizer
      第83回応用物理学会秋季学術講演会
    • Related Report
      2022 Annual Research Report
  • [Presentation] The launch of "Multicellular Neurobiocomputing"2022

    • Author(s)
      H. Yamamoto, Y. Katori, T. Matsui, Y. Masamizu
    • Organizer
      The 1st Symposium on Multicellular Neurobiocomputing (The 10th RIEC International Symposium on Brain Functions and Brain Computer)
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Remarks] 領域ホームページ

    • URL

      https://www.mnbc.riec.tohoku.ac.jp/

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report
  • [Remarks] 第3回領域国際シンポジウムホームページ

    • URL

      https://www.mnbc.riec.tohoku.ac.jp/symposium2023.html

    • Related Report
      2023 Annual Research Report
  • [Remarks] 第2回領域国際シンポジウムホームページ

    • URL

      https://www.mnbc.riec.tohoku.ac.jp/symposium2022.html

    • Related Report
      2022 Annual Research Report
  • [Remarks] シンポジウム「次世代ICTと未来医療を支える神経科学・神経工学・脳型コンピューティング」(開催報告)

    • URL

      https://www.jsap.or.jp/docs/jsap-meeting/report2022a/report2022a-symposiumT14.pdf

    • Related Report
      2022 Annual Research Report
  • [Remarks] 領域ホームページ

    • URL

      https://www.mnbc.riec.tohoku.ac.jp/index.html

    • Related Report
      2021 Annual Research Report
  • [Remarks] キックオフ国際シンポジウムホームページ

    • URL

      https://www.mnbc.riec.tohoku.ac.jp/symposium2021.html

    • Related Report
      2021 Annual Research Report
  • [Funded Workshop] The 3rd Symposium on Multicellular Neurobiocomputing2024

    • Related Report
      2023 Annual Research Report
  • [Funded Workshop] The 2nd Symposium on Multicellular Neurobiocomputing2023

    • Related Report
      2022 Annual Research Report
  • [Funded Workshop] The 1st Symposium on Multicellular Neurobiocomputing2022

    • Related Report
      2021 Annual Research Report

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Published: 2021-10-22   Modified: 2025-01-30  

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