| Budget Amount *help |
¥368,550,000 (Direct Cost: ¥283,500,000、Indirect Cost: ¥85,050,000)
Fiscal Year 2014: ¥68,120,000 (Direct Cost: ¥52,400,000、Indirect Cost: ¥15,720,000)
Fiscal Year 2013: ¥71,370,000 (Direct Cost: ¥54,900,000、Indirect Cost: ¥16,470,000)
Fiscal Year 2012: ¥74,880,000 (Direct Cost: ¥57,600,000、Indirect Cost: ¥17,280,000)
Fiscal Year 2011: ¥74,230,000 (Direct Cost: ¥57,100,000、Indirect Cost: ¥17,130,000)
Fiscal Year 2010: ¥79,950,000 (Direct Cost: ¥61,500,000、Indirect Cost: ¥18,450,000)
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| Outline of Final Research Achievements |
We introduced next generation sequencers, and developed various tools and algorithms for genome informatics to analyze data generated by next generation sequencers. These facilities and genome informatics are shared by the researchers in this research project.To establish reference genome sequence of Japanese genome, we developed a new algorithm employing long reads obtained using the Pacific Biosciences sequencer along with error correction using short reads obtained using HiSeq sequencers. This algorithm facilitated detection of structural variations. To detect expanded short tandem repeats that are frequently associated with neurodegenerative diseases, a new algorithm to detect expanded short tandem repeats was debeloped, which was shared by the researchers in this research project.
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