| Project Area | Molecular Science for Nanomedicine |
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| Project/Area Number |
23107001
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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| Allocation Type | Single-year Grants |
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| Review Section |
Science and Engineering
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| Research Institution | The University of Tokyo |
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Principal Investigator |
ISHIHARA KAZUHIKO 東京大学, 工学(系)研究科(研究院), 教授 (90193341)
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| Co-Investigator(Kenkyū-buntansha) |
HIGUCHI Hideo 東京大学, 大学院理学系研究科, 教授 (90165093)
IWATA Hiroo 京都大学, 再生医科学研究所, 教授 (30160120)
NATSUME Atsushi 名古屋大学, 大学院医学系研究科, 准教授 (30362255)
URISU Tsuneo 名古屋大学, 未来社会創造機構, 客員教授 (50249950)
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| Co-Investigator(Renkei-kenkyūsha) |
FUKUDA Norio 東京慈恵会医科大学, 医学部, 准教授 (30301534)
YUI Nobuhiko 東京医科歯科大学, 生体材料工学研究所, 教授 (70182665)
MARUYAMA Atsushi 東京工業大学, 生命理工学研究科, 教授 (40190566)
MIYAKE Jun 大阪大学, 基礎工学研究科, 教授 (70344174)
GONDA Kosuke 東北大学, 大学院医学系研究科, 教授 (80375435)
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| Project Period (FY) |
2011-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥100,360,000 (Direct Cost: ¥77,200,000、Indirect Cost: ¥23,160,000)
Fiscal Year 2015: ¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2014: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2013: ¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2012: ¥42,900,000 (Direct Cost: ¥33,000,000、Indirect Cost: ¥9,900,000)
Fiscal Year 2011: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Keywords | ナノメディシン分子科学 / 細胞環境 / 細胞機能 / 分子イメージング / 薬物送達システム / 細胞内診断 / 組織再生医療 / バイオイメージング / 生体材料 / 先端計測 / ナノバイオ / ナノデバイス / 細胞・組織 / 生物物理 / ナノメディシン / 細胞内動態 / 細胞・組織工学 / ナノマテリアル / 分子科学 / 化学反応パラメーター / 分子反応 / 反応パラメーター |
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| Outline of Final Research Achievements |
Nanomedicine molecular science focuses on molecular reactions in the cells, which constitute the living organism and control its biological activities. The cellular environment, however, differs from the chemical reaction environment. The goal of this project is to develop molecular reaction parameters to quantify and examine such reactions. The studies are part of a scientific initiative focusing on cells and have the following main objectives: establishing the theoretical basis of molecular reactions in the cell, and understanding the cellular environment and intracellular chemical reaction mechanisms. They include topics related to the origin of cellular functions, which provide knowledge indispensable for molecular nanomedicine; topics required for establishing molecular nanomedicine; topics that may help integrate the research projects and promote constructive interactions among researchers; and topics that encourage original ideas to solve difficulties in the field.
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