| Co-Investigator(Renkei-kenkyūsha) |
Hanai Taizo 九州大学, 大学院農学研究院, 准教授 (60283397)
Tagawa Yoichi 東京工業大学, 大学院生命理工学研究科, 准教授 (70262079)
Tsuge Kenji 慶応義塾大学, 大学院政策・メディア研究科, 講師 (70399690)
Kiga Daisuke 東京工業大学, 大学院総合理工学研究院, 准教授 (30376587)
Rondelez Yannick 東京大学, 生産技術研究所, 准教授 (10548770)
Suyama Akira 東京大学, 大学院総合文化研究科, 教授 (90163063)
Yamamura Masayuki 東京工業大学, 大学院総合理工学研究院, 教授 (00220442)
Iba Hitoshi 東京大学, 大学院工学系研究院, 教授 (40302773)
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| Budget Amount *help |
¥61,100,000 (Direct Cost: ¥47,000,000、Indirect Cost: ¥14,100,000)
Fiscal Year 2015: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2014: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
Fiscal Year 2013: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Fiscal Year 2012: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Fiscal Year 2011: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
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| Outline of Final Research Achievements |
In order to make the paradigm shift from the concept of “watched and analyzed biology” to that of “synthetic and analyzed or utilized biology”, the innovative research named Synthetic Biology was started from 2000 in US, such as designing synthetic genetic circuit by combining known interrelated biomaterials, realizing a certain bio-functional behaviors
such as switch, oscillation, in vivo, designing synthetic metabolic pathways by incorporating enzyme coded genes from other origins into the cells. The objectives of this research project is to establish the coordination between the fundamental technologies for synthetic biology in order to comprehend biomolecular networks by integrating the following three missions: 1)design synthetic genetic circuit or metabolic pathway with using the methods of computational science, 2) construct the circuit
in vitro with using the method of engineering, 3) construct the circuit in vivo or in the cell with using the methods of molecular biology.
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