Promotion of the Transcription Cycle Area

• Project Area: Integral understanding of the mechanism of transcription cycle through quantitative, high-resolution approaches
• Project/Area Number: 24118001
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: YAMAGUCHI Yuki 東京工業大学, 生命理工学院, 教授 (50345360)
• Co-Investigator(Kenkyū-buntansha): 十川 久美子 東京工業大学, 生命理工学院, 准教授 (20291073) ; 中村 春木 大阪大学, たんぱく質研究所, 教授 (80134485) ; 松本 直通 横浜市立大学, 医学(系)研究科(研究院), 教授 (80325638) ; 高橋 陽介 広島大学, 理学(系)研究科(研究院), 教授 (90183855) ; 緒方 一博 横浜市立大学, 医学(系)研究科(研究院), 教授 (90260330) ; 伊藤 敬 長崎大学, 医歯(薬)学総合研究科, 教授 (90306275)
• Research Collaborator: ISHI Shunsuke 理化学研究所, 主任研究員 ; TANAKA Kiyoji 大阪大学, 教授 ; HIROSE Susumu 国立遺伝学研究所, 教授 ; SHIOMI Haruhiko 慶応義塾大学, 教授 ; SATO Fumitoshi 東京大学, 教授
• Project Period (FY): 2012-06-28 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥119,340,000 (Direct Cost: ¥91,800,000、Indirect Cost: ¥27,540,000); Fiscal Year 2016: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000); Fiscal Year 2015: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000); Fiscal Year 2014: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000); Fiscal Year 2013: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000); Fiscal Year 2012: ¥81,250,000 (Direct Cost: ¥62,500,000、Indirect Cost: ¥18,750,000)
• Keywords: 転写サイクル / 遺伝子 / 発現制御 / 生体生命情報学 / 分子認識 / １分子計測

Outline of Final Research Achievements

The goal of the Transcription Cycle Area is to gain an integrative perspective on multiple steps and layers of transcription using “high-resolution approaches,” in which leading edge technology and computational science are combined with conventional methodology. To facilitate research activity of the area toward this goal, the following support programs were conducted as planned: (1) Establishment and management of the Transcription Cycle Core Facility. (2) Promotion of cooperation within the Area and with outside groups. (3) Support of young researchers. (4) Public relations.

Research Products

• [Int'l Joint Research] システムバイオロジー研究所/UT Southwestern Medical Center at Dallas/カーネギー研究所(米国)
• [Int'l Joint Research] オックスフォード大学(英国)
• [Journal Article] 転写反応の生化学 (2017)
  • Author(s): 山口雄輝
  • Journal Title: 生体の科学 Volume: 68(3)
• [Journal Article] Autophosphorylation affects substrate-binding affinity of tobacco Ca2+-dependent protein kinase1 (2017)
  • Author(s): Ito, T., Ishida, S., Oe, S., Fukazawa, J. and Takahashi, Y.
  • Journal Title: Plant Physiol. Volume: 印刷中
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] DELLA-GAF1 complex is a main component in gibberellin feedback regulation of GA20ox2 in Arabidopsis (2017)
  • Author(s): Fukazawa, J., Mori, M., Watanabe, S., Miyamoto, C., Ito, T. and Takahashi, Y.
  • Journal Title: Plant Physiol. Volume: 印刷中
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Conformational changes in inhibitory PAS domain protein associated with binding of HIF-1α and Bcl-xL in living cells (2017)
  • Author(s): S. Kasai, S. Kajimoto, Y. Ito, T. Saito, K. Yasumoto, M. Tokunaga, K. Sakata-Sogawa, H. Fukumura, K. Sogawa
  • Journal Title: J. Biochem. Volume: 161 Pages: 291-296
  • DOI: 10.1093/jb/mvw068
  • NAID: 40021162091
  • Peer Reviewed / Open Access
• [Journal Article] MKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses (2017)
  • Author(s): Shin C, Ito Y, Ichikawa S, Tokunaga M, Sakata-Sogawa K, Tanaka T
  • Journal Title: Scientific Reports Volume: 7 Issue: 1 Pages: 46097-46097
  • DOI: 10.1038/srep46097
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A novel GFI1B mutation at the first zinc finger domain causes congenital macrothrombocytopenia (2017)
  • Author(s): Uchiyama Y, Ogawa Y, Kunishima S, Shiina M, Nakashima M, Yanagisawa K, Yokohama A, Imagawa E, Miyatake S, Mizuguchi T, Takata A, Miyake N, Ogata K, Handa H, Matsumoto N
  • Journal Title: British Journal of Haematology Volume: 印刷中 Issue: 6 Pages: 843-847
  • DOI: 10.1111/bjh.14710
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Molecular mechanisms of cooperative binding of transcription factors Runx1-CBFβ-Ets1 on the TCRα gene enhancer (2017)
  • Author(s): Kasahara K, Shiina M, Fukuda I, Ogata K, Nakamura H
  • Journal Title: PloS One Volume: 12 Issue: 2 Pages: e0172654-e0172654
  • DOI: 10.1371/journal.pone.0172654
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing (2017)
  • Author(s): Lardelli RM, Schaffer AE, Eggens VR, ... Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG
  • Journal Title: Nature Genetics Volume: 49 Issue: 3 Pages: 457-464
  • DOI: 10.1038/ng.3762
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] PARS2 and NARS2 mutations in infantile-onset neurodegenerative disorder (2017)
  • Author(s): Mizuguchi T, Nakashima M, Kato M, Yamada K, Okanishi T, Ekhilevitch N, Mandel H, Eran A, Toyono M, Sawaishi Y, Motoi H, Shiina M, Ogata K, Miyatake S, Miyake N, Saitsu H, Matsumoto N
  • Journal Title: Journal of Human Genetics Volume: 62 Issue: 5 Pages: 525-529
  • DOI: 10.1038/jhg.2016.163
  • NAID: 40021210259
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Biallelic mutations in MYPN, encoding Myopalladin, are associated with childhood-onset, slowly progressive nemaline myopathy (2017)
  • Author(s): Miyatake S, Mitsuhashi S, Hayashi YK, Purevjav E, Nishikawa A, Koshimizu E, Suzuki M, Yatabe K, Tanaka Y, Ogata K, Kuru S, Shiina M, Tsurusaki Y, Nakashima M, Mizuguchi T, Miyake N, Saitsu H, Ogata K, Kawai M, Towbin J, Nonaka I, Nishino I, Matsumoto N
  • Journal Title: American Journal of Human Genetics Volume: 100 Issue: 1 Pages: 169-178
  • DOI: 10.1016/j.ajhg.2016.11.017
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Distal arthrogryposis with variable clinical expression caused by TNNI2 mutation (2017)
  • Author(s): Culic V, Miyake N, Jankovic S, Petrovic D, Simunovic M, Dapic T, Shiina M, Ogata K, Matsumoto N
  • Journal Title: Human Genome Variation Volume: 3 Issue: 1 Pages: 16035-16035
  • DOI: 10.1038/hgv.2016.35
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] The first report of Japanese patients with asparagine synthetase deficiency (2017)
  • Author(s): Yamamoto T, Endo W, Ohnishi H, Kubota K, Kawamoto N, Inui T, Imamura A, Takanashi JI, Shiina M, Saitsu H, Ogata K, Matsumoto N, Haginoya K, Fukao T
  • Journal Title: Brain Development Volume: 39 Issue: 3 Pages: 236-242
  • DOI: 10.1016/j.braindev.2016.09.010
  • Peer Reviewed
• [Journal Article] Biallelic TBCD mutations cause early-onset neurodegenerative encephalopathy (2017)
  • Author(s): Miyake N, Fukai R, Ohba C, ... Shiina M, Ogata K, Okuno-Yuguchi J, Fueki N, Ogiso Y, Suzumura H, Watabe Y, Imataka G, Leong HY, Fattal-Valevski A, Kramer U, Miyatake S, Kato M, Okamoto N, Sato Y, Mitsuhashi S, Nishino I, Kaneko N, Nishiyama A, Tamura T, Mizuguchi T, Nakashima M, Tanaka F, Saitsu H, Matsumoto N
  • Journal Title: American Journal of Human Genetics Volume: 99 Issue: 4 Pages: 950-961
  • DOI: 10.1016/j.ajhg.2016.08.005
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Enhancement of canonical sampling by virtual-state transitions (2017)
  • Author(s): Junichi Higo, Kota Kasahara, Bhaskar Dasgupta, Haruki Nakamura
  • Journal Title: J. Chem. Phys. Volume: 146 Issue: 4 Pages: 44104-44104
  • DOI: 10.1063/1.4974087
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Ultra-sensitive droplet digital PCR for detecting a low-prevalence somatic GNAQ mutation in Sturge-Weber syndrome. (2016)
  • Author(s): Uchiyama Y, Nakashima M, Watanabe S, Miyajima M, Taguri M, Miyatake S, Miyake N, Saitsu H, Mishima H, Kinoshita A, Arai H, Yoshiura K, Matsumoto N.
  • Journal Title: Scientific Reports Volume: 6 Issue: 1 Pages: 22985-22985
  • DOI: 10.1038/srep22985
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] FDG-PET study of patients with Leigh syndrome (2016)
  • Author(s): Haginoya K, Kaneta T, Togashi N, Hino-Fukuyo N, Kobayashi T, Uematsu M, Kitamura T, Inui T, Okubo Y, Takezawa Y, Anzai M, Endo W, Miyake N, Saitsu H, Matsumoto N, Kure S.
  • Journal Title: J Neurol Sci Volume: 362 Pages: 309-313
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Pathogenic Variants in PIGG Cause Intellectual Disability with Seizures and Hypotonia (2016)
  • Author(s): Makrythanasis P, Kato M, Zaki MS, Saitsu H, Nakamura K, Santoni FA, Miyatake S, Nakashima M, Issa MY, Guipponi M, Letourneau A, Logan CV, Roberts N, Parry DA, Johnson CA, Matsumoto N, Hamamy H, Sheridan E, Kinoshita T, Antonarakis SE, Murakami Y.
  • Journal Title: Am J Hum Genet Volume: 98 Issue: 4 Pages: 615-626
  • DOI: 10.1016/j.ajhg.2016.02.007
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Mislocalization of syntaxin-1 and impaired neurite growth observed in a human iPSC model for STXBP1-related epileptic encephalopathy. (2016)
  • Author(s): Yamashita S, Chiyonobu T, Yoshida M, Maeda H, Zuiki M, Kidowaki S, Isoda K, Morimoto M, Kato M, Saitsu H, Matsumoto N, Nakahata T, Saito MK, Hosoi H
  • Journal Title: Epilepsia Volume: 57 Issue: 4
  • DOI: 10.1111/epi.13338
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Detection of low-prevalence somatic TSC2 mutations in sporadic pulmonary lymphangioleiomyomatosis tissues by deep sequencing. (2016)
  • Author(s): Fujita A, Ando K, Kobayashi E, Mitani K, Okudera K, Nakashima M, Miyatake S, Tsurusaki Y, Saitsu H, Seyama K, Miyake N, Matsumoto N.
  • Journal Title: Hum Genet. Volume: 135(1) Issue: 1 Pages: 61-68
  • DOI: 10.1007/s00439-015-1611-0
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A novel homozygous mutation in HSF4 causing autosomal recessive congenital cataract. (2016)
  • Author(s): Behnam M, Imagawa E, Chaleshtori AR, Ronasian F, Salehi M, Miyake N, Matsumoto N.
  • Journal Title: J Hum Genet. Volume: 61 Issue: 2 Pages: 177-179
  • DOI: 10.1038/jhg.2015.127
  • NAID: 40020742278
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Novel COL4A1 mutation in an infant with severe dysmorphic syndrome with schizencephaly, periventricular calcifications, and cataract resembling congenital infection. (2016)
  • Author(s): Smigiel R, Cabala M, Jakubiak A, Kodera H, Sasiadek MJ, Matsumoto N, Sasiadek MM, Saitsu H.
  • Journal Title: Birth Defects Res A Clin Mol Teratol Volume: 106 Issue: 4 Pages: 304-307
  • DOI: 10.1002/bdra.23488
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Homozygous p.V116* mutation in C12orf65 results in Leigh syndrome. (2016)
  • Author(s): Imagawa E, Fattal-Valevski A, Eyal O, Miyatake S, Saada A, Nakashima M, Tsurusaki Y, Saitsu H, Miyake N, Matsumoto N.
  • Journal Title: J Neurol Neurosurg Psychiatry. Volume: 87(2) Pages: 212-216
  • DOI: 10.1136/jnnp-2014-310084
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] De novo missense mutations in NALCN cause developmental and intellectual impairment with hypotonia (2016)
  • Author(s): Fukai R, Saitsu H, Okamoto N, Sakai Y, Fattal-Valevski A, Masaaki S, Kitai Y, Torio M, Kojima-Ishii K, Ihara K, Nakashima M, Miyatake S, Tanaka F, Miyake N, Matsumoto N
  • Journal Title: J Hum Genet Volume: 61 Issue: 5 Pages: 451-455
  • DOI: 10.1038/jhg.2015.163
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Dyschromatosis symmetrica hereditaria and Aicardi-Goutires syndrome 6 are phenotypic variants caused by ADAR1 mutations. (2016)
  • Author(s): Kono M, Matsumoto F, Suzuki Y, Suganuma M, Saitsu H, Ito Y, Fujiwara S, Matsumoto K, Moriwaki S, Matsumoto N, Tomita Y, Sugiura K, Akiyama M.
  • Journal Title: J Invest Dermatol. Volume: 136 Issue: 4 Pages: 875-8
  • DOI: 10.1016/j.jid.2015.12.034
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Vein of Galen Aneurysmal malformation in monozygotic twin (2016)
  • Author(s): Komiyama M, Miyatake M Watanabe Y, Terada A, Ishiguro T, Ichiba H, Matsumoto M
  • Journal Title: World Neurosurg Volume: 91:672 Pages: 672.e11-672.e15
  • DOI: 10.1016/j.wneu.2016.04.031
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] De novo KCNH1 mutations in four patients with syndromic developmental delay, hypotonia and seizures. (2016)
  • Author(s): Fukai R, Saitsu H, Tsurusaki Y, Sakai Y, Haginoya K, Takahashi K, Hubshman MW, Okamoto N, Nakashima M, Tanaka F, Miyake N, Matsumoto N
  • Journal Title: J Hum Genet Volume: 61 Issue: 5 Pages: 381-387
  • DOI: 10.1038/jhg.2016.1
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Two cases of early-onset myoclonic seizures with continuous parietal delta activity caused by EEF1A2 mutations. (2016)
  • Author(s): Inui T, Kobayashi S, Ashikari Y, Sato R, Endo W, Uematsu M, Oba H, Saitsu H, Matsumoto N, Kure S, Haginoya K.
  • Journal Title: Brain Dev. Volume: 38 Issue: 5 Pages: 520-4
  • DOI: 10.1016/j.braindev.2015.11.003
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Impaired neuronal KCC2 function by biallelic SLC12A5 mutations in migrating focal seizures and severe developmental delay. (2016)
  • Author(s): Saitsu H, Watanabe M, Akita T, Ohba C, Sugai K, Ong WP, Shiraishi H, Yuasa S, Matsumoto H, Beng KT, Saitoh S, Miyatake S, Nakashima M, Miyake N, Kato M, Fukuda A. and Matsumoto N.
  • Journal Title: Scientific Reports Volume: 6 Issue: 1 Pages: 30072-30072
  • DOI: 10.1038/srep30072
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] De novo truncating mutation of TRIM8 causes early-onset epileptic encephalopathy (2016)
  • Author(s): Sakai Y#, Fukai R# (# denotes equal contribution), Matsushita Y, Miyake N, Saitsu H, Akamine S, Torio M, Sasazaki M, Ishizaki Y, Sanefuji M, Torisu H, Shaw CA, Matsumoto N, Hara T
  • Journal Title: Ann Hum Genet Volume: 80 Issue: 4 Pages: 235-240
  • DOI: 10.1111/ahg.12157
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] SMARCE1, a rare cause of Coffin-Siris Syndrome: Clinical description of three additional cases (2016)
  • Author(s): Zarate YA, Bhoj E, Kaylor J, Li D, Tsurusaki Y, Miyake N, Matsumoto N, Phadke S, Escobar L, Irani A, Hakonarson H, Schrier Vergano SA
  • Journal Title: Am J Med Genet A Volume: 170 Issue: 8 Pages: 1967-1973
  • DOI: 10.1002/ajmg.a.37722
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] SAMD9 mutations cause a novel multisystem disorder, MIRAGE syndrome, and are associated with loss of chromosome 7 (2016)
  • Author(s): Narumi S*, et al., Matsumoto N, et al.
  • Journal Title: Nat Genet Volume: 48 Issue: 7 Pages: 792-797
  • DOI: 10.1038/ng.3569
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] De novo p.Arg756Cys mutation of ATP1A3 causes an atypical form of alternating hemiplegia of childhood with prolonged paralysis and choreoathetosis (2016)
  • Author(s): Kanemasa H, Fukai R, Sakai Y, Torio M, Miyake N, Lee S, Ono H, Akamine S, Nishiyama K, Sanefuji M, Ishizaki Y, Torisu H, Saitsu H, Matsumoto N, Hara T
  • Journal Title: BMC Neurol Volume: 16 Issue: 1 Pages: 174-174
  • DOI: 10.1186/s12883-016-0680-6
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The first genetically confirmed Japanese patient with mucolipidosis type IV (2016)
  • Author(s): Saijo H, Hayashi M, Ezoe T, Ohba C, Saitsu H, Kurata K, Matsumoto N
  • Journal Title: Clin Case Rep Volume: 4 Issue: 5 Pages: 509-512
  • DOI: 10.1002/ccr3.540
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The first Japanese case of leukodystrophy with ovarian failure arising from novel compound heterozygous AARS2 mutations (2016)
  • Author(s): Hamatani M, Jingami N, Tsurusaki Y, Shimada S, Shimojima K, Asada-Utsugi M, Yoshinaga K, Uemura N, Yamashita H, Uemura K, Takahashi R, Matsumoto N, Yamamoto T
  • Journal Title: J Hum Genet Volume: 61 Issue: 10 Pages: 899-902
  • DOI: 10.1038/jhg.2016.64
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Molecular genetic analysis of 30 families with Joubert syndrome (2016)
  • Author(s): Suzuki T, et al., Matsumoto N
  • Journal Title: Clin Genet Volume: 90 Issue: 6 Pages: 526-535
  • DOI: 10.1111/cge.12836
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Distinct but milder phenotypes with choreiform movements in siblings with compound heterozygous mutations in the transcription preinitiation mediator complex subunit 17 (MED17) (2016)
  • Author(s): Hirabayashi S, Saitsu H, Matsumoto N
  • Journal Title: Brain Dev Volume: 38 Issue: 1 Pages: 118-123
  • DOI: 10.1016/j.braindev.2015.05.004
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Diagnosis of pancreatic lesions collected by endoscopic ultrasound-guided fine-needle aspiration using next-generation sequencing (2016)
  • Author(s): Kameta E, Sugimori K, Kaneko T, Ishii T, Miwa H, Sato T, Ishii Y, Sue S, Sasaki T, Yamashita Y, Shibata W, Matsumoto N, Maeda S
  • Journal Title: Oncol Lett Volume: 12 Issue: 5 Pages: 3875-3881
  • DOI: 10.3892/ol.2016.5168
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Autosomal-recessive mutations in AP3B2, adaptor-related protein complex 3 beta 2 subunit, cause an early-onset epileptic encephalopathy with optic atrophy (2016)
  • Author(s): Assoum M, Philippe C, et al., Matsumoto N, et al.
  • Journal Title: Am J Hum Genet Volume: 99 Issue: 6 Pages: 1368-1376
  • DOI: 10.1016/j.ajhg.2016.10.009
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The molecular and phenotypic spectrum of IQSEC2-related epilepsy (2016)
  • Author(s): Zerem A, et al., Matsumoto N, et al.
  • Journal Title: Epilepsia Volume: 57 Issue: 11 Pages: 1858-1869
  • DOI: 10.1111/epi.13560
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Association between invisible basal ganglia and ZNF335 mutations: a case report (2016)
  • Author(s): Sato R, Takanashi J, Tsuyusaki Y, Kato M, Saitsu H, Matsumoto N, Takahashi T
  • Journal Title: Pediatrics Volume: 138 Issue: 3
  • DOI: 10.1542/peds.2016-0897
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Megalencephaly, polymicrogyria and ribbon-like band heterotopia: A new cortical malformation (2016)
  • Author(s): Kobayashi Y, Magara S, Okazaki K, Komatsubara T, Saitsu H, Matsumoto N, Kato M, Tohyama J
  • Journal Title: Brain Dev Volume: 38 Issue: 10 Pages: 950-953
  • DOI: 10.1016/j.braindev.2016.06.004
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] A female case of aromatic l-amino acid decarboxylase deficiency responsive to MAO-B inhibition (2016)
  • Author(s): Kojima K, Anzai R, Ohba C, Goto T, Miyauchi A, Thony B, Saitsu H, Matsumoto N, Osaka H, Yamagata T
  • Journal Title: Brain Dev Volume: 38 Issue: 10 Pages: 959-963
  • DOI: 10.1016/j.braindev.2016.06.002
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Clinical features of SMARCA2 duplication overlap with Coffin-Siris syndrome (2016)
  • Author(s): Miyake N, Abdel-Salam G, Yamagata T, Eid MM, Osaka H, Okamoto N, Mohamed AM, Ikeda T, Afifi HH, Piard J, van Maldergem L, Mizuguchi T, Miyatake S, Tsurusaki Y, Matsumoto N
  • Journal Title: Am J Med Genet A Volume: 170 Issue: 10 Pages: 2662-2670
  • DOI: 10.1002/ajmg.a.37778
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] De novo MEIS2 mutation causes syndromic developmental delay with persistent gastro-esophageal reflux (2016)
  • Author(s): Fujita A, Isidor B, Piloquet H, Corre P, Okamoto N, Nakashima M, Tsurusaki Y, Saitsu H, Miyake N, Matsumoto N
  • Journal Title: J Hum Genet Volume: 61 Issue: 9 Pages: 835-838
  • DOI: 10.1038/jhg.2016.54
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] First Japanese variant of late infantile neuronal ceroid lipofuscinosis caused by novel CLN6 mutations (2016)
  • Author(s): Sato R, Inui T, Endo W, Okubo Y, Takezawa Y, Anzai M, Morita H, Saitsu H, Matsumoto N, Haginoya K
  • Journal Title: Brain Dev Volume: 38 Issue: 9 Pages: 852-826
  • DOI: 10.1016/j.braindev.2016.04.007
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Identification of biallelic LRRK1 mutations in osteosclerotic metaphyseal dysplasia and evidence for locus heterogeneity (2016)
  • Author(s): Iida A, Xing W, Docx MK, Nakashima T, Wang Z, Kimizuka M, Van Hul W, Rating D, Spranger J, Ohashi H, Miyake N, Matsumoto N, Mohan S, Nishimura G, Mortier G, Ikegawa S
  • Journal Title: J Med Genet Volume: 53 Issue: 8 Pages: 568-574
  • DOI: 10.1136/jmedgenet-2016-103756
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] High prevalence of genetic alterations in early-onset epileptic encephalopathies associated with infantile movement disorders. (2016)
  • Author(s): Kobayashi Y, Tohyama J, Kato M, Akasaka N, Magara S, Kawashima H, Ohashi T, Shiraishi H, Nakashima M, Saitsu H, Matsumoto N.
  • Journal Title: Brain Dev. Volume: 38 Issue: 7 Pages: 285-92
  • DOI: 10.1038/jhg.2016.27
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Milder progressive cerebellar atrophy caused by biallelic SEPSECS mutations (2016)
  • Author(s): Iwama K, Sasaki M, Hirabayashi S, Ohba C, Iwabuchi E, Miyatake S, Nakashima M, Miyake N, Ito S, Saitsu H, Matsumoto N
  • Journal Title: J Hum Genet Volume: 61 Issue: 6 Pages: 527-531
  • DOI: 10.1038/jhg.2016.9
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Dermatan 4-O-sulfotransferase 1-deficient Ehlers-Danlos syndrome complicated by a large subcutaneous hematoma on the back. (2016)
  • Author(s): Mochida K, Amano M, Miyake N, Matsumoto N, Hatamochi A, Kosho T.
  • Journal Title: J Dermatol. Volume: Epub ahead of print Issue: 7 Pages: 1-2
  • DOI: 10.1111/1346-8138.13273
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] mDCC_tools: Characterizing Multi-modal Atomic Motions in Molecular Dynamics Trajectories (2016)
  • Author(s): Kota Kasahara, Neetha Mohan, Ikuo Fukuda, Haruki Nakamura
  • Journal Title: Bioinformatics Volume: 32 Issue: 16 Pages: 2531-2533
  • DOI: 10.1093/bioinformatics/btw129
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Elastic properties of dynein motor domain obtained from all-atom molecular dynamics simulations (2016)
  • Author(s): Narutoshi Kamiya, Tadaaki Mashimo, Yu Takano, Takahide Kon, Genji Kurisu, Haruki Nakamura
  • Journal Title: Protein Engineering, Design and Selection Volume: 29 Issue: 8 Pages: 317-325
  • DOI: 10.1093/protein/gzw022
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Rapid and efficient analysis of gene function using CRISPR-Cas9 in Xenopus tropicalis founders (2016)
  • Author(s): Shigeta, Mitsuki; Sakane, Yuto; Iida, Midori; Suzuki, Miyuki; Kashiwagi, Keiko; Kashiwagi, Akihiko; Fujii, Satoshi; Yamamoto, Takashi; Suzuki, Ken-ichi
  • Journal Title: Genes to Cells Volume: in press Issue: 7 Pages: 755-771
  • DOI: 10.1111/gtc.12379
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Revisiting Antibody Modeling Assessment for CDR-H3 loop (2016)
  • Author(s): Hiroshi Nishigami, Narutoshi Kamiya, Haruki Nakamura
  • Journal Title: Protein Engineering, Design and Selection Volume: 29 Issue: 11 Pages: 477-484
  • DOI: 10.1093/protein/gzw028
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Identification of aryl hydrocarbon receptor signaling pathways altered in TCDD- treated red seabream embryos by transcriptome analysis (2016)
  • Author(s): Midori Iida, Satoshi Fujii, Masaya Uchida, , Hiroshi Nakamura, Yoshihiro Kagami, Tetsuro Agusa, Masashi Hirano, Su-Min Bak, Eun-Young Kim, Hisato Iwata
  • Journal Title: Aquatic Toxicology Volume: 177 Pages: 156-170
  • DOI: 10.1016/j.aquatox.2016.05.014
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] myPresto/omegagene: a GPU-accelerated molecular dynamics simulator tailored for enhanced conformational sampling methods with a non-Ewald electrostatic scheme (2016)
  • Author(s): Kota Kasahara, Benson Ma, Kota Goto, Bhaskar Dasgupta, Junichi Higo, Ikuo Fukuda, Tadaaki Mashimo, Yutaka Akiyama, Haruki Nakamura
  • Journal Title: Biophysics and Physicobiology Volume: 13 Issue: 0 Pages: 209-216
  • DOI: 10.2142/biophysico.13.0_209
  • NAID: 130007041560
  • ISSN: 2189-4779
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Variation of Free-Energy Landscape of the p53 C-terminal Domain Induced by Acetylation: Enhanced Conformational Sampling (2016)
  • Author(s): Shinji Iida, Tadaaki Mashimo, Takashi Kurosawa, Hironobu Hojo, Hiroya Muta, Yuji Goto, Yoshifumi Fukunishi, Haruki Nakamura, Junichi Higo
  • Journal Title: J. Comput. Chem. Volume: 37 Issue: 31 Pages: 2687-2700
  • DOI: 10.1002/jcc.24494
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance. (2016)
  • Author(s): Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M.
  • Journal Title: Nature Communications Volume: 7 Issue: 1 Pages: 11030-11030
  • DOI: 10.1038/ncomms11030
  • NAID: 130007529314
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] SMARCAD1 is an ATP-dependent stimulator of nucleosomal H2A acetylation via CBP, resulting in transcriptional regulation. (2016)
  • Author(s): Doiguchi M
  • Journal Title: Sci. Rep. Volume: 6 Issue: 1 Pages: 20179-20179
  • DOI: 10.1038/srep20179
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Phenotypic spectrum of GNAO1 variants: epileptic encephalopathy to involuntary movements with severe developmental delay (2016)
  • Author(s): Saitsu H, Fukai R, Ben-Zeev B, Sakai Y, Mimaki M, Okamoto N, Suzuki Y, Monden Y, Saito H, Tziperman B, Torio M, Akamine S, Takahashi N, Osaka H, Yamagata T, Nakamura K, Tsurusaki Y, Nakashima M, Miyake N, Shiina M, Ogata K, Matsumoto N
  • Journal Title: Eur J Hum Genet Volume: 24(1) Issue: 1 Pages: 129-134
  • DOI: 10.1038/ejhg.2015.92
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2016)
  • Author(s): Klionsky DJ., Abdelmohsen K., Abe A., Abedin MJ.,Inomata M., et al.
  • Journal Title: Autophagy Volume: 12(1) Issue: 1 Pages: 1-222
  • DOI: 10.1080/15548627.2015.1100356
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] FDG-PET study of patients with Leigh syndrome (2016)
  • Author(s): Haginoya K, Kaneta T, Togashi N, Hino-Fukuyo N, Kobayashi T, Uematsu M, Kitamura T, Inui T, Okubo Y, Takezawa Y, Anzai M, Endo W, Miyake M, Saitsu H, Matsumoto N, Kure S
  • Journal Title: Journal of the Neurological Sciences Volume: 362 Pages: 309-313
  • DOI: 10.1016/j.jns.2016.02.008
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Omokage search: shape similarity search service for biomolecular structures in both the PDB and EMDB. (2016)
  • Author(s): Hirofumi Suzuki, Takeshi Kawabata, Haruki Nakamura
  • Journal Title: Ｂｉｏｉｎｆｏｒｍａｔｉｃｓ Volume: 32 Issue: 4 Pages: 619-620
  • DOI: 10.1093/bioinformatics/btv614
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Development of Massive Multilevel Molecular Dynamics Simulation Program, Platypus (PLATform for dYnamic Protein Unified Simulation), for the Elucidation of Protein (2016)
  • Author(s): Takano Y, Nakata K, Yonezawa Y, Nakamura H
  • Journal Title: Journal of Computational Chemistry Volume: 37 Issue: 12 Pages: 1125-1132
  • DOI: 10.1002/jcc.24318
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A critical appraisal of the zero-multipole method: Structural, thermodynamic, dielectrid, and dynamical properties of a water system (2016)
  • Author(s): Wang H, Nakamura H, Fukuda I
  • Journal Title: Journal of Chemical Physics Volume: 144 Issue: 11 Pages: 114503-114503
  • DOI: 10.1063/1.4943956
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Density functional study of molecular interactions in secondary structures of proteins (2016)
  • Author(s): Takano Y, Kusaka A, Nakamura H
  • Journal Title: Biophysics and Physicobiology Volume: 13 Issue: 0 Pages: 27-35
  • DOI: 10.2142/biophysico.13.0_27
  • NAID: 130005126232
  • ISSN: 2189-4779
  • Peer Reviewed / Open Access
• [Journal Article] De novo GABRA1 mutations in Ohtahara and West syndromes (2015)
  • Author(s): ○Hirofumi Kodera, et al, Hirotomo Saitsu and Naomichi Matsumoto
  • Journal Title: Epilepsia Volume: 57 Issue: 4 Pages: 566-573
  • DOI: 10.1111/epi.13344
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Panventriculomegaly with a wide foramen of Magendie and large cisterna magna. (2015)
  • Author(s): Hiroshi Kageyama, Masakazu Miyajima, Ikuko Ogino, Madoka Nakajima, Kazuaki Shimoji, Ryoko Fukai, Noriko Miyake, Kenichi Nishiyama, Naomichi Matsumoto, Hajime Arai
  • Journal Title: Journal of Neurosurgery Volume: E-pub Issue: 6 Pages: 1-9
  • DOI: 10.3171/2015.6.jns15162
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Non-overlapping Functions of Rtf1 and the Paf1 Complex. (2015)
  • Author(s): Cao, Q. F., C., Yamamoto, J., Isobe, T., Tateno, S., Murase, Y., Chen, Y., Handa, H. and Yamaguchi, Y.
  • Journal Title: Mol Cell. Biol. Volume: 35 Issue: 20 Pages: 3459-3470
  • DOI: 10.1128/mcb.00601-15
  • Peer Reviewed / Open Access
• [Journal Article] CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription. (2015)
  • Author(s): Laitem, C., Zaborowska, J., Tellier, M., Yamaguchi, Y., Cao. Q.-F., Egloff, S., Handa, H., and Murphy, S.
  • Journal Title: Transcription Volume: 6 Pages: 79-90
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Enhancer of Acetyltransferase Chameau(EAChm) Is a Novel Transcriptional Co-Activator (2015)
  • Author(s): Takeya Nakagawa, Tsuyoshi Ikehara, Masamichi Doiguchi, Yuko Imamura, Miki Higashi, Mitsuhiro Yoneda, Takashi Ito
  • Journal Title: PLoS ONE Volume: 10(11) Issue: 11 Pages: e0142305-e0142305
  • DOI: 10.1371/journal.pone.0142305
  • NAID: 120006987224
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation. (2015)
  • Author(s): Inoue D, Aihara H, Sato T, Mizusaki H, Doiguchi M, Higashi M, Imamura Y, Yoneda M, Miyanishi T, Fujii S, Okuda A, Nakagawa T, Ito T
  • Journal Title: Scientific Reports Volume: 5 Issue: 1 Pages: 16567-16567
  • DOI: 10.1038/srep16567
  • NAID: 120006986837
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Binding of GID1 to DELLAs Promotes Dissociation of GAF1 from DELLA in GA Dependent Manner (2015)
  • Author(s): Fukazawa, J., Ito, T., Yoshida, M., Kamiya, Y., Yamaguchi, S., and Takahashi, Y.
  • Journal Title: Plant Signaling and Behavior Volume: 10 Issue: 10 Pages: e1052923-e1052923
  • DOI: 10.1080/15592324.2015.1052923
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Short-lasting unilateral neuralgiform headache attacks with ispilateral facial flushing is a new variant of paroxysmal extreme pain disorder (2015)
  • Author(s): Imai N, Miyake N, Saito Y, Kobayashi E, Ikawa M, Manaka S, Shiina M, Ogata K, Matsumoto N
  • Journal Title: J Headache Pain Volume: 16(1) Issue: 1 Pages: 519-519
  • DOI: 10.1186/s10194-015-0519-3
  • Peer Reviewed / Open Access
• [Journal Article] A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions (2015)
  • Author(s): Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Uchiyama A, Baba S, Sato K, Yamamoto M, Ogata K
  • Journal Title: J Mol Biol Volume: 427(8) Issue: 8 Pages: 1655-1669
  • DOI: 10.1016/j.jmb.2014.07.020
  • Peer Reviewed / Open Access
• [Journal Article] Novel compound heterozygous LIAS mutations cause glycine encephalopathy (2015)
  • Author(s): Tsurusaki Y, Tanaka R, Shimada S, Shimojima K, Shiina M, Nakashima M, Saitsu H, Miyake N, Ogata K, Yamamoto T, Matsumoto N
  • Journal Title: J Hum Genet Volume: 60(10) Issue: 10 Pages: 631-635
  • DOI: 10.1038/jhg.2015.72
  • Peer Reviewed / Open Access
• [Journal Article] De novo SHANK3 mutation causes a female patient with Rett syndrome like phenotype. (2015)
  • Author(s): Hara M, Ohba C, Yamashita Y, Saitsu H, Matsumoto N, Matsuishi T.
  • Journal Title: J Med Genet Part A Volume: 167(7) Issue: 7 Pages: 1593-1596
  • DOI: 10.1002/ajmg.a.36775
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Japanese familial case of myoclonus-dystonia syndrome with a splicing mutation in SGCE. (2015)
  • Author(s): Wada T, Takano K, Tsurusaki Y, Miyake N, Nakashima M, Saitsu H, Matsumoto N, Osaka H.
  • Journal Title: Pediatr Int. Volume: 57 Issue: 2 Pages: 324-326
  • DOI: 10.1111/ped.12613
  • NAID: 120005666180
  • Peer Reviewed / Open Access
• [Journal Article] A family of distal arthrogryposis type 5 due to a novel PIEZO2 mutation (2015)
  • Author(s): Okubo M, Fujita A, Saito Y, Komaki H, Ishiyama A, Kojima E, Koichihara R, Saito T, Nakagawa E, Sugai K, Yamazaki H, Kusaka K, Tanaka H, Matsumoto N, Sasaki M
  • Journal Title: Am J Med Genet Part A Volume: 167(5) Issue: 5 Pages: 1100-1106
  • DOI: 10.1002/ajmg.a.36881
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Mutations in the glutaminyl-tRNA synthetase gene cause early-onset epileptic encephalopathy. (2015)
  • Author(s): Kodera H, Osaka H, Iai M, Aida N, Yamashita A, Tsurusaki Y, Nakashima M, Miyake N, Saitsu H, Matsumoto N.
  • Journal Title: J Hum Genet. Volume: 60(2) Issue: 2 Pages: 97-101
  • DOI: 10.1038/jhg.2014.103
  • Peer Reviewed / Open Access
• [Journal Article] Detecting copy number variations in whole exome sequencing data using exome hidden markov model - an expectation of “exome-first” approach. (2015)
  • Author(s): Miyatake S, Koshimizu E, Fujita A, Fukai R, Imagawa E, Ohba C, Kuki I, Makita Y, Ogata T, Nakashima M, Tsurusaki Y, Miyake N, Saitsu H, Matsumoto N
  • Journal Title: J Hum Genet Volume: 1 Issue: 4 Pages: 124-124
  • DOI: 10.1038/jhg.2014.124
  • Peer Reviewed / Open Access
• [Journal Article] SPTAN1 encephalopathy: distinct phenotypes and genotypes (2015)
  • Author(s): Tohyama J, Nakashima M, Nabatame S, Gaik-Siew C, Miyata R, Rener-Primec Z, Kato M, Matsumoto N, Saitsu H
  • Journal Title: Journal of Human Genetics Volume: 60(4) Issue: 4 Pages: 167-173
  • DOI: 10.1038/jhg.2015.5
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] GRIN1 mutations cause encephalopathy with infantile-onset epilepsy, and hyperkinetic and stereotyped movement disorders (2015)
  • Author(s): Ohba C, Shiina M, Tohyama J, Haginoya K, Lerman-Sagie T, Okamoto N, Blumkin L, Lev D, Mukaida S, Nozaki F, Uematsu M, Onuma A, Kodera H, Nakashima M, Tsurusaki Y, Miyake N, Tanaka F, Kato M, Ogata K, Saitsu H, Matsumoto N
  • Journal Title: Epilepsia Volume: 印刷中 Issue: 6 Pages: 841-848
  • DOI: 10.1111/epi.12987
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Sporadic infantile-onset spinocerebellar ataxia caused by missense mutations of the inositol 1,4,5-triphosphate receptor type 1 gene. (2015)
  • Author(s): Sasaki M, Ohba C, Iai M, Hirabayashi S, Osaka H, Hiraide T, Saitsu H, Matsumoto N
  • Journal Title: J Neurol Volume: 262(5) Issue: 5 Pages: 1278-1284
  • DOI: 10.1007/s00415-015-7705-8
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A Japanese case of cerebellar ataxia, spastic paraparesis and deep sensory impairment associated with a novel homozygous TTC19 mutation (2015)
  • Author(s): Kunii M, Doi H, Higashiyama Y, Kugimoto C, Ueda N, Hirata J, Tomita-Katsumoto A, Kashikura-Kojima M, Kubota S, Taniguchi M, Murayama K, Nakashima M, Tsurusaki Y, Miyake N, Saitsu H, Matsumoto N, Tanaka F.
  • Journal Title: J Hum Genet Volume: 60 Issue: 4 Pages: 187-191
  • DOI: 10.1038/jhg.2015.7
  • NAID: 40020433141
  • Peer Reviewed / Open Access
• [Journal Article] A case of autism spectrum disorder arising from a de novo missense mutation in POGZ. (2015)
  • Author(s): Fukai R, Hiraki Y, Yofune H, Tsurusaki Y, Nakashima M, Saitsu H, Tanaka F, Miyake N, Matsumoto N.
  • Journal Title: J Hum Genet. Volume: 60(5) Issue: 5 Pages: 277-279
  • DOI: 10.1038/jhg.2015.13
  • Peer Reviewed / Open Access
• [Journal Article] An Aberrant Splice Acceptor Site Due to a Novel Intronic Nucleotide Substitution in MSX1 Gene Is the Cause of Congenital Tooth Agenesis in a Japanese Family (2015)
  • Author(s): Tatematsu T, Kimura M, Nakashima M, Machida J, Yamaguchi S, Shibata A, Goto H, Nakayama A, Higashi Y, Miyachi H, Shimozato K, Matsumoto N, Tokita Y
  • Journal Title: Plos One Volume: 10(6) Issue: 6 Pages: e0128227-e0128227
  • DOI: 10.1371/journal.pone.0128227
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A novel mutation in ELOVL4 leading to spinocerebellar ataxia (SCA) with the hot cross bun sign but lacking erythrokeratodermia: a broadened spectrum of SCA34. (2015)
  • Author(s): Ozaki K, Doi H, Mitsui J, Sato N, Iikuni Y, Majima T, Yamane K, Irioka T, Ishiura H, Doi K, Morishita S, Higashi M, Sekiguchi T, Koyama K, Ueda N, Miura Y, Miyatake S, Matsumoto N, Yokota T, Tanaka F, Tsuji S, Mizusawa H, Ishikawa K.
  • Journal Title: JAMA Neurology Volume: 72 Issue: 7 Pages: 797-805
  • DOI: 10.1001/jamaneurol.2015.0610
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Novel rare variations of the oxytocin receptor (OXTR) gene in autism spectrum disorder individuals. (2015)
  • Author(s): Liu X, Kawashima M, Miyagawa T, Otowa T, Latt KZ, Thiri M, Nishida H, Sugiyama T, Tsurusaki Y, Matsumoto N, Mabuchi A, Tokunaga K, Sasaki T.
  • Journal Title: Human Genome Variation Volume: 2 Issue: 1 Pages: 15024-15024
  • DOI: 10.1038/hgv.2015.24
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Predominant cerebellar phenotype in spastic paraplegia 7 (SPG7). (2015)
  • Author(s): Yahikozawa H, Yoshida K, Shunichi S, Hanyu N, Doi H, Miyatake S, Matsumoto N.
  • Journal Title: Human Genome Variation Volume: 2 Issue: 1 Pages: 15015-15015
  • DOI: 10.1038/hgv.2015.12
  • Peer Reviewed / Open Access
• [Journal Article] Somatic Mutations in the MTOR gene cause focal cortical dysplasia type IIb (2015)
  • Author(s): Nakashima M, Saitsu H, Takei N, Tohyama J, Kato M, Kitaura H, Shiina M, Shirozu H, Masuda H, Watanabe K, Ohba C, Tsurusaki Y, Miyake N, Zheng Y, Sato T, Takebayashi H, Ogata K, Kameyama S, Kakita A, Matsumoto N
  • Journal Title: Ann. Neurol. Volume: 78 Issue: 3 Pages: 375-386
  • DOI: 10.1002/ana.24444
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Two novel homozygous RAB3GAP1 mutations cause Warburg micro syndrome. (2015)
  • Author(s): Imagawa E, Fukai R, Behnam M, Goyal M, Nouri N, Nakashima M, Tsurusaki Y, Saitsu H, Salehi M, Kapoor S, Tanaka F, Miyake N, Matsumoto N.
  • Journal Title: Hum Genome Var. Volume: 2 Issue: 1 Pages: 15034-15034
  • DOI: 10.1038/hgv.2015.34
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Electroclinical features of epileptic encephalopathy caused by SCN8A mutation (2015)
  • Author(s): Takahashi S, Yamamoto S, Okayama A, Araki A, Saitsu H, Matsumoto N, Azuma H
  • Journal Title: Pediatrics International Volume: 57(4) Issue: 4 Pages: 758-762
  • DOI: 10.1111/ped.12622
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis. (2015)
  • Author(s): Kubo N, Toh H, Shirane K, Shirakawa T, Kobayashi H, Sato T, Sone H, Sato Y, Tomizawa S, Tsurusaki Y, Shibata H, Saitsu H, Suzuki Y, Matsumoto N, Suyama M, Kono T, Ohbo K, Sasaki H.
  • Journal Title: BMC Genomics. Volume: 16 Issue: 1 Pages: 624-624
  • DOI: 10.1186/s12864-015-1833-5
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] De Novo 17q24.2-q24.3 microdeletion presenting with generalized hypertrichosis terminalis, gingival fibromatous hyperplasia, and distinctive facial features (2015)
  • Author(s): Afifi H, Fukai R, Miyake N, Gamal E, Din A, Eid M, Eid O, Thomas M, El-Badry T, Tosson A, Abdel-Salam G, Matsumoto N
  • Journal Title: Am J Med Genet Part A Volume: 167(10) Issue: 10 Pages: 2418-2424
  • DOI: 10.1002/ajmg.a.37185
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Biallelic mutations in nuclear pore complex subunit NUP107 cause early-childhood-onset steroid-resistant nephrotic syndrome (2015)
  • Author(s): Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N
  • Journal Title: Am J Hum Genet Volume: 97(4) Issue: 4 Pages: 555-566
  • DOI: 10.1016/j.ajhg.2015.08.013
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Identification of HOXD4 Mutations in Spinal Extradural Arachnoid Cyst (2015)
  • Author(s): Ogura Y, Miyake N, Kou I, Iida A, Nakajima M, Takeda K, Fujibayashi S, Shiina M, Okada E, Toyama Y, Iwanami A, Ishii K, Ogata K, Asahara H, Matsumoto N, Nakamura M, Matsumoto M, Ikegawa S
  • Journal Title: PLoS One Volume: 10(11) Issue: 11 Pages: e0142126-e0142126
  • DOI: 10.1371/journal.pone.0142126
  • NAID: 120005763410
  • Peer Reviewed / Open Access
• [Journal Article] De novo KCNB1 mutations in infantile epilepsy inhibit repetitive neuronal firing. (2015)
  • Author(s): Saitsu, H., T. Akita, J. Tohyama, H. Goldberg-Stern, Y. Kobayashi, R. Cohen, M. Kato, C. Ohba, S. Miyatake, Y. Tsurusaki, M. Nakashima, N. Miyake, A. Fukuda, and N. Matsumoto
  • Journal Title: Sci Rep Volume: 5 Issue: 1 Pages: 15199-15199
  • DOI: 10.1038/srep15199
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] De novo DNM1 mutations in two cases of epileptic encephalopathy. (2015)
  • Author(s): Nakashima M, Kouga T, Lourenço CM, Shiina M, Goto T, Tsurusaki Y, Miyatake S, Miyake N, Saitsu H, Ogata K, Osaka H, Matsumoto N.
  • Journal Title: Epilepsia Volume: Epub 2015 Nov 27. Issue: 1
  • DOI: 10.1111/epi.13257
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Virtual-system coupled adaptive umbrella sampling to compute free-energy landscape for flexible molecular docking (2015)
  • Author(s): Higo J, Dasgupta B, Mashimo T, Kasahara K, Fukunishi Y, Nakamura H
  • Journal Title: Journal of Computational Chemistry Volume: 36 Issue: 20 Pages: 1489-1501
  • DOI: 10.1002/jcc.23948
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Computational Study of Drug Binding Affinity to Influenza A Neuraminidase Using Smooth Reaction Path Generation (SRPG) Method (2015)
  • Author(s): Nguyen H, Tran T, Fukunishi Y, Higo J, Nakamura H, Le L
  • Journal Title: Journal of Chemical Information and Modeling Volume: 55 Issue: 9 Pages: 1936-1943
  • DOI: 10.1021/acs.jcim.5b00319
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes (2015)
  • Author(s): M.-A. Kawano, K. Doi, H. Fukuda, Y. Kita, K. Imai, T. Inoue, T. Enomoto, M. Matsui, M. Hatakeyama, Y. Yamaguchi, H. Handa
  • Journal Title: Biotechnol. Rep. Volume: 5 Pages: 105-111
  • DOI: 10.1016/j.btre.2014.12.008
  • Peer Reviewed / Open Access
• [Journal Article] Phosphatase protection assay: 14-3-3 binding protects the phosphate group of RSG from λ protein phosphatase (2015)
  • Author(s): Ito, T. and Takahashi, Y.
  • Journal Title: Bio-Protocol Volume: 5
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Identification of diphtheria toxin R domain mutants with enhanced inhibitory activity against HB-EGF (2015)
  • Author(s): Suzuki K, Mizushima H, Abe H, Iwamoto R, Nakamura H, Mekada E
  • Journal Title: J Biochem Volume: mvu079 Issue: 5 Pages: 331-343
  • DOI: 10.1093/jb/mvu079
  • NAID: 40020461422
  • Peer Reviewed / Open Access
• [Journal Article] A Japanese girl with an early-infantile onset vanishing white matter disease resembling Cree leukoencephalopathy. (2014)
  • Author(s): Takano K, Tsuyusaki Y, Sato M, Takagi M, Anzai R, Okuda M, Iai M, Yamashita S,
  • Journal Title: Brain Dev. Volume: 37(6) Issue: 6 Pages: 638-42
  • DOI: 10.1016/j.braindev.2014.10.002
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Dominant mutations in ORAI1 cause tubular-aggregate-myopathy with hypocalcemia by constitutive activation of store-operated Ca2+ channel (2014)
  • Author(s): Endo Y, Noguchi S, Hara Y, Hayashi YK, Motomura K, Murakami N, Tanaka S, Yamashita S, Kizu R, Bamba M, Goto Y, Matsumoto N, Nonaka I, Nishino I.
  • Journal Title: Hum Mol Genet Volume: 24（3） Issue: 3 Pages: 637-648
  • DOI: 10.1093/hmg/ddu477
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Identification and in vivo functional characterization of novel compound heterozygous BMP1 variants in osteogenesis imperfecta. (2014)
  • Author(s): Cho SY, Asharani PV, Kim OH, Iida A, Miyake N, Matsumoto N, Nishimura G, Ki CS, Hong G, Kim SJ, Sohn YB, Park SW, Lee J, Kwun Y, Carney TJ, Huh R, Ikegawa S, Jin DK.
  • Journal Title: Hum Mutat Volume: 36（2） Issue: 2 Pages: 191-5
  • DOI: 10.1002/humu.22731
  • Peer Reviewed / Open Access
• [Journal Article] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes (2014)
  • Author(s): J. Yamamoto, Y. Hagiwara, K. Chiba, T. Isobe, T. Narita, H. Handa, Y. Yamaguchi
  • Journal Title: Nat. Commun. Volume: 5 Issue: 1 Pages: 4263-4263
  • DOI: 10.1038/ncomms5263
  • Peer Reviewed / Open Access
• [Journal Article] Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata (2014)
  • Author(s): M. Takemoto, Y. Kawamura, M. Hirohama, Y. Yamaguchi, H. Handa, H. Saitoh, Y. Nakao, M. Kawada, K. Khalid, H. Koshino, K. Kimura, A. Ito, M. Yoshida
  • Journal Title: J. Antibiot. (Tokyo) Volume: 67 Issue: 4 Pages: 335-338
  • DOI: 10.1038/ja.2013.142
  • Peer Reviewed / Open Access
• [Journal Article] Magnetically promoted rapid immunoreactions using functionalized fluorescent magnetic beads: a proof of principle (2014)
  • Author(s): S. Sakamoto, K. Omagari, Y. Kita, Y. Mochizuki, Y. Naito, S. Kawata, S. Matsuda, O. Itano, H. Jinno, H. Takeuchi, Y. Yamaguchi, Y. Kitagawa, H. Handa
  • Journal Title: Clin Chem. Volume: 60 Issue: 4 Pages: 610-620
  • DOI: 10.1373/clinchem.2013.211433
  • Peer Reviewed
• [Journal Article] Scaffold function of Ca2+-dependent protein kinase: NtCDPK1 transfers 14-3-3 to the substrate RSG after phosphorylation (2014)
  • Author(s): Ito T, Nakata M, Fukazawa J, Ishida S, Takahashi Y.
  • Journal Title: Plant Physiol. Volume: 165 Issue: 4 Pages: 1737-1750
  • DOI: 10.1104/pp.114.236448
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] DELLAs function as coactivators of GAI ASSOCIATED FACTOR1 in regulation of GA homeostasis and signaling in Arabidopsis (2014)
  • Author(s): Fukazawa J, Teramura H, Murakoshi S, Nasuno K, Nishida N, Ito T, Yoshida M, Kamiya Y, Yamaguchi S, Takahashi Y.
  • Journal Title: Plant Cell Volume: 26 Issue: 7 Pages: 2920-2938
  • DOI: 10.1105/tpc.114.125690
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Phosphorylation-independent binding of 14-3-3 to NtCDPK1 by a new mode (2014)
  • Author(s): Ito T, Nakata M, Fukazawa J, Ishida S, Takahashi Y.
  • Journal Title: Plant Signal Behav. Volume: 9 Issue: 12 Pages: e977721-e977721
  • DOI: 10.4161/15592324.2014.977721
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Crystallization of the Ets1-Runx1-CBFβ-DNA complex formed on the TCRα gene enhancer (2014)
  • Author(s): Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Baba S, Sato K, Ogata K
  • Journal Title: Acta Crystallogr F Struct Biol Commun Volume: 70 Issue: 10 Pages: 1380-1384
  • DOI: 10.1107/s2053230x14018470
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] A hemizygous GYG2 mutation and Leigh syndrome: a possible link? (2014)
  • Author(s): Imagawa E, Osaka H, Yamashita A, Shiina M, Takahashi E, Sugie H, Nakashima M, Tsurusaki Y, Saitsu H, Ogata K, Matsumoto N, Miyake N.
  • Journal Title: Hum Genet. Volume: 133(2 Issue: 2 Pages: 225-34
  • DOI: 10.1007/s00439-013-1372-6
  • Peer Reviewed / Open Access
• [Journal Article] Regulation of RNA polymerase II activation by histone acetylation in single living cells (2014)
  • Author(s): Stasevich TJ, Hayashi-Takanaka Y, Sato Y, Maehara K, Ohkawa Y, Sakata-Sogawa K, Tokunaga M, Nagase T, Nozaki N, McNally JG, Kimura H
  • Journal Title: Nature Volume: 516 Issue: 7530 Pages: 272-275
  • DOI: 10.1038/nature13714
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A Facile Preparation of Glass-supported Lipid Bilayers for Analyzing Molecular Dynamics (2014)
  • Author(s): Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga
  • Journal Title: Analytical Sciences Volume: 30 Issue: 12 Pages: 1103-1106
  • DOI: 10.2116/analsci.30.1103
  • NAID: 130004704345
  • ISSN: 0910-6340, 1348-2246
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Nuclear actin activates human transcription factor genes including the OCT4 gene (2014)
  • Author(s): Yamazaki S., Yamamoto K., Tokunaga M., Sakata-Sogawa K., Harata M.
  • Journal Title: Biosci Biotechnol Biochem Volume: 79 Pages: 242-246
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Clinical exome sequencing in neurology practice (2014)
  • Author(s): Miyatake S,Matsumoto N.
  • Journal Title: Nat Rev Neurol Volume: 10（12） Issue: 12 Pages: 676-678
  • DOI: 10.1038/nrneurol.2014.213
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] De novo SOX11 mutations cause Coffin-Siris syndrome (2014)
  • Author(s): Tsurusaki Y, Ohashi H, Phadke S, Koshimizu E, Kou I, Shiina M, Suzuki T, Okamoto N, Imamura S, Yamashita M, Watanabe S, Yoshiura K-i, Kodera H, Miyatake S, Nakashima N, Saitsu H, Ogata K, Ikegawa S, Miyake N, and Matsumoto N.
  • Journal Title: Nat Commun Volume: 5 Issue: 1 Pages: 4011-4011
  • DOI: 10.1038/ncomms5011
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Expanding the phenotypic spectrum of TUBB4A-associated (2014)
  • Author(s): Miyatake S, Osaka H, Shiina M, Sasaki M, Takanashi J, Haginoya K, Wada T,
  • Journal Title: Neurology Volume: 82(24) Issue: 24 Pages: 2230-7
  • DOI: 10.1212/wnl.0000000000000535
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] PIGA mutations cause early-onset epileptic encephalopathies and distinctive features (2014)
  • Author(s): Kato M, Saitsu H, Murakami Y , Kikuchi K, Watanabe S, Iai M, Miya K, Matsuura R, Takayama R, Ohba C, Nakashima M, Tsurusaki Y, Miyake N, Hamano S, Osaka H, Hayasaka K, Kinoshita T, Matsumoto N.
  • Journal Title: Neurology Volume: 82（18） Issue: 18 Pages: 1587-1596
  • DOI: 10.1212/wnl.0000000000000389
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] AKT3 and PIK3R2 mutations in two patients with megalencephaly-related syndromes (2014)
  • Author(s): Nakamura K, Kato M, Tohyama J, Shiohama T, Hayasaka K, Nishiyama K, Kodera H, Nakashima M, Tsurusaki Y, Miyake N, Matsumoto N, Saitsu H.
  • Journal Title: Clin Genet Volume: 85（4） Issue: 4 Pages: 396-398
  • DOI: 10.1111/cge.12188
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] PIGN mutations cause congenital anomalies, developmental delay, hypotonia, epilepsy, and progressive cerebellar atrophy (2014)
  • Author(s): Ohba C, Okamoto N, Murakami Y, Kawato K, Suzuki Y, Ikeda T, Tsurusaki Y, Nakashima M, Miyake N, Tanaka F, Kinoshita T, Matsumoto N, Saitsu H .
  • Journal Title: Neurogenet Volume: 15（2） Issue: 2 Pages: 85-92
  • DOI: 10.1007/s10048-013-0384-7
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Early onset epileptic encephalopathy caused by de novo SCN8A mutations (2014)
  • Author(s): Ohba C, Kato M, Takahashi S, Lerman-Sagie T, Lev D, Terashima H, Kubota M, Kawawaki H, Matsufuji M, Kojima Y, Tateno A, Goldberg-Stern H, Straussberg R, Marom D, Leshinsky-Silver E, Nakashima M, Nishiyama K, Tsurusaki Y, Miyake N, Tanaka F, Matsumoto N, Saitsu H:
  • Journal Title: Epilepsia Volume: 55 Issue: 7 Pages: 994-1000
  • DOI: 10.1111/epi.12668
  • Peer Reviewed
• [Journal Article] De novo WDR45 mutation in a patient showing clinically Rett syndrome with childhood iron deposition in brain (2014)
  • Author(s): Ohba C, Nabatame S, Iijima Y, Nishiyama K, Tsurusaki Y, Nakashima M, Miyake N, Tanaka F, Ozono K, Saitsu H, Matsumoto N.
  • Journal Title: J Hum Genet Volume: 59（5） Issue: 5 Pages: 292-295
  • DOI: 10.1038/jhg.2014.18
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Deep sequencing detects very low-grade somatic mosaicism in the unaffected mother of siblings with nemaline myopathy (2014)
  • Author(s): Miyatake S, Koshimizu E, Hayashi YK, Miya K, Shiina M, Nakashima M, Tsurusaki Y, Miyake N, Saitsu H, Ogata K, Nishino I, Matsumoto N.
  • Journal Title: Neuromuscul Disord Volume: 24（7） Issue: 7 Pages: 642-647
  • DOI: 10.1016/j.nmd.2014.04.002
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Novel compound heterozygous PIGT mutations caused multiple congenital anomalies-hypotonia-seizures syndrome 3 (2014)
  • Author(s): Nakashima M, Kashii H, Murakami Y, Kato M, Tsurusaki Y, Miyake N, Kubota M, Kinoshita T, Saitsu H, Matsumoto N.
  • Journal Title: Neurogenet Volume: 15（3） Issue: 3 Pages: 193-200
  • DOI: 10.1007/s10048-014-0408-y
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Numerous BAF complex genes are mutated in Coffin-Siris syndrome (2014)
  • Author(s): Miyake N, Tsurusaki Y, Matsumoto N.
  • Journal Title: Am J Med Genet Part C Volume: 166c（3） Issue: 3 Pages: 257-261
  • DOI: 10.1002/ajmg.c.31406
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Causative novel PNKP mutations and concomitant PCDH15 mutations in a patient with microcephaly with early-onset seizures and developmental delay syndrome and hearing loss (2014)
  • Author(s): Nakashima M, Takano K, Osaka H, Aida N, Tsurusaki Y, Miyake N, Saitsu H, Matsumoto N.
  • Journal Title: J Hum Genet Volume: 59（8） Issue: 8 Pages: 471-474
  • DOI: 10.1038/jhg.2014.51
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Whole exome analysis identifies frequent CNGA1 mutations in Japanese population with autosomal recessive retinitis pigmentosa (2014)
  • Author(s): Katagiri S, Akahori M, Sergeev Y, Yoshitake K, Ikeo K, Furuno M, Hayashi T, Kondo M, Ueno S, Tsunoda K, Shinoda K, Kuniyoshi K, Tsurusaki Y, Matsumoto N, Tsuneoka H, Iwata T.
  • Journal Title: Plos One Volume: 9（9） Issue: 9 Pages: e108721-e108721
  • DOI: 10.1371/journal.pone.0108721
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Whole exome sequencing revealed biallelic IFT122 mutations in a family with CED1 and recurrent pregnancy loss. (2014)
  • Author(s): Tsurusaki Y, Yonezawa R, Furuya M, Nishimura G, Pooh R, Nakashima M, Saitsu H, Miyake N, Saito S, Matsumoto N.
  • Journal Title: Clin Genet. Volume: 85 Issue: 6 Pages: 592-594
  • DOI: 10.1111/cge.12215
  • Peer Reviewed
• [Journal Article] Coffin-Siris syndrome is a SWI/SNF complex disorder (2014)
  • Author(s): Tsurusaki Y, Okamoto N, Ohashi H, Mizuno S, Matsumoto N, Makita Y, Fukuda M, Isidor B, Perrier J, Aggarwal S, Al-Kindy A, Liebelt J, Mowat D, Nakashima M, Saitsu H, Miyake N, Matsumoto N.
  • Journal Title: Clin Genet Volume: 85（6） Issue: 6 Pages: 548-554
  • DOI: 10.1111/cge.12225
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] De novo EEF1A2 mutations in patients with characteristic facial features, intellectual disability and, autistic behaviors and epilepsy (2014)
  • Author(s): Nakajima J, Okamoto N, Tohyama J, Kato M, Arai H, Funahashi O, Tsurusakia Y, Nakashima M, Kawashima H, Saitsu H, Matsumoto N, Miyake N.
  • Journal Title: Clin Genet Volume: 87(4) Issue: 4 Pages: 356-361
  • DOI: 10.1111/cge.12394
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Late-onset spastic ataxia phenotype in a patient with a homozygous DDHD2 mutation (2014)
  • Author(s): Doi H, Ushiyama M, Baba T, Tani K, Shiina M, Ogata K, Miyatake S, Yuzawa YF, Tsuji S, Nakashima M, Tsurusaki Y, Miyake N, Saitsu H, Ikeda S, Tanaka F, Matsumoto N, Yoshida K
  • Journal Title: Sci Rep Volume: 4 Issue: 1 Pages: 7132-7132
  • DOI: 10.1038/srep07132
  • NAID: 120007100602
  • Peer Reviewed / Open Access
• [Journal Article] Atypical giant axonal neuropathy arising from a homozygous mutation by uniparental isodisomy (2014)
  • Author(s): Miyatake S, Koshimizu E, Tada H, Satoshi Moriya S, Takanashi J, Hirano Y, Hayashi M, Nakashima M, Tsurusaki Y, Miyake N, Matsumoto N, Saitsu H.
  • Journal Title: Clin Genet Volume: 87（4） Issue: 4 Pages: 395-397
  • DOI: 10.1111/cge.12455
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] High-resolution modeling of antibody structures by a combination of bioinformatics, expert knowledge, and molecular simulations. (2014)
  • Author(s): Hiroki Shirai, Kazuyoshi Ikeda, Kazuo Yamashita, Yuko Tsuchiya, Jamica Sarmiento, Shide Liang, Tatsuaki Morokata, Kenji Mizuguchi, Junichi Higo, Daron M. Standley, Haruki Nakamura
  • Journal Title: Proteins Volume: 印刷中 Issue: 8 Pages: 1624-1635
  • DOI: 10.1002/prot.24591
  • Peer Reviewed / Open Access
• [Journal Article] The Zero-multipole summation method for estimating electrostatic interactions in molecular dynamics : analysis of the accuracy and application to liquid systems (2014)
  • Author(s): Fukuda I, Kamiya N, Nakamura H
  • Journal Title: J. Chem. Phys Volume: 140 Issue: 19 Pages: 194307-194307
  • DOI: 10.1063/1.4875693
  • NAID: 120005596268
  • Peer Reviewed / Open Access
• [Journal Article] 3D flexible alignment using 2D maximum common substructure: dependence of prediction accuracy on target-reference chemical similarity (2014)
  • Author(s): Takeshi Kawabata, Haruki Nakamura
  • Journal Title: Journal of Chemical Information and Modeling Volume: 54 (7) Issue: 7 Pages: 1850-1863
  • DOI: 10.1021/ci500006d
  • Peer Reviewed
• [Journal Article] Structure of the entire stalk region of the dynein motor domain (2014)
  • Author(s): Yosuke Nishikawa, Takuji Oyama, Narutoshi Kamiya, Takahide Kon, Yoko Y. Toyoshima, Haruki Nakamura, Genji Kurisu
  • Journal Title: Journal of Molecular Biology Volume: 426 Issue: 19 Pages: 3232-3245
  • DOI: 10.1016/j.jmb.2014.06.023
  • Peer Reviewed
• [Journal Article] Kotai Antibody Builder: Automated, high-resolution structural modeling of antibodies (2014)
  • Author(s): Kazuo Yamashita, Kazuyoshi Ikeda, Karlou Amada, Shide Liang, Yuko Tsuchiya,Haruki Nakamura, Hiroki Shirai, Daron M Standley
  • Journal Title: Bioinformatics Volume: 30 (22) Pages: 3279-3280
  • Peer Reviewed
• [Journal Article] A Novel Approach of Dynamic Cross Correlation Analysis on Molecular Dynamics Simulations and its Application to Ets1 dimer–DNA Complex (2014)
  • Author(s): Kota Kasahara, Ikuo Fukuda, Haruki Nakamura
  • Journal Title: PLoS One Volume: 9 (11) Issue: 11 Pages: e112419-e112419
  • DOI: 10.1371/journal.pone.0112419
  • NAID: 120005596267
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The specification and global reprogramming of histone epigenetic marks during gamete formation and early embryo development in C. elegans (2014)
  • Author(s): Samson M, Jow MM, Wong CC, Fitzpatrick C, Aslanian A, Saucedo I, Estrada R, Ito T, Park SK, Yates JR, Chu, DS
  • Journal Title: PLoS Genet Volume: 10 Issue: 10 Pages: e1004588-e1004588
  • DOI: 10.1371/journal.pgen.1004588
  • NAID: 120006986360
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe (2014)
  • Author(s): Asakawa H, Yang HJ, Yamamoto T G, Ohtsuki C, Chikashige Y, Sakata-Sogawa K, Tokunaga M, Iwamoto M, Hiraoka Y, Haraguchi T.
  • Journal Title: Nucleus Volume: 5(印刷中) Issue: 2 Pages: 1-14
  • DOI: 10.4161/nucl.28487
  • Peer Reviewed / Open Access
• [Journal Article] Scaffold function of Ca2+-dependent protein kinase: NtCDPK1 transfers 14-3-3 to the substrate RSG after phosphorylation (2014)
  • Author(s): Ito, T., Nakata, M., Fukazawa, J., Ishida, S. and Takahashi, Y.
  • Journal Title: Plant Physiol. Volume: in press
  • Peer Reviewed
• [Journal Article] Vesnarinone Suppresses TNF α mRNA Expression by Inhibiting Valosin-containing Protein (2013)
  • Author(s): Hotta K, Nashimoto A, Yasumura E, Suzuki M, Azuma M, Iizumi Y, Shima D, Nabeshima R, Hiramoto M, Okada A, Sakata-Sogawa K, Tokunaga M, Ito T, Ando H, Sakamoto S, Kabe Y, Aizawa S, Imai T, Yamaguchi Y, Watanabe H, Handa H
  • Journal Title: Mol Pharmacol Volume: Vol.83 Issue: 5 Pages: 930-938
  • DOI: 10.1124/mol.112.081935
  • Peer Reviewed
• [Journal Article] Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1 (2013)
  • Author(s): T. Enomoto, M.-A. Kawano, H. Fukuda, W. Sawada, T. Inoue, K. C. Haw, Y. Kita, S. Sakamoto, Y. Yamaguchi, T. Imai, M. Hatakeyama, S. Saito, A. Sandhu, M. Matsui, I. Aoki, H. Handa
  • Journal Title: J. Biotechnol. Volume: 167 Issue: 1 Pages: 8-15
  • DOI: 10.1016/j.jbiotec.2013.06.005
  • Peer Reviewed
• [Journal Article] Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression (2013)
  • Author(s): Isobe, T., Song, S.-N. J., Tiwari, P., Ito, H., Yamaguchi, Y., and Yoshizaki, K.
  • Journal Title: FEBS Letters Volume: 587 Issue: 16 Pages: 2487-2492
  • DOI: 10.1016/j.febslet.2013.06.028
  • Peer Reviewed
• [Journal Article] Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity (2013)
  • Author(s): V. Gupta, S. Liu, H. Ando, R. Ishii, S. Tateno, Y. Kaneko, M. Yugami, S. Sakamoto, Y. Yamaguchi, O. Nureki, H. Handa
  • Journal Title: Mol. Pharmacol. Volume: 84 Issue: 6 Pages: 824-833
  • DOI: 10.1124/mol.113.087940
  • Peer Reviewed
• [Journal Article] Mitochondrial complex III deficiency caused by a homozygous UQCRC2 mutation presenting with neonatal-onset recurrent metabolic decompensation (2013)
  • Author(s): Miyake N^<#>, Yano S^<#> (# denotes equal contribution), Sakai C, Hatakeyama H, Shiina M, Watanabe Y, Bartley J, Abdenur JE, Wang RY, Chang R, Tsurusaki Y, Doi H, Saitsu H, Ogata K, Goto Y, *Matsumoto N
  • Journal Title: Hum Mut Volume: 34(3):446-452 Issue: 3 Pages: 446-452
  • DOI: 10.1002/humu.22257
  • Peer Reviewed
• [Journal Article] Exome sequencing identifies a novel INPPL1 mutation in opsismodysplasia (2013)
  • Author(s): Iida A, Okamoto N, Miyake N, Nishimura G, Minami S, Sugimoto T, Nakashima M, Tsurusaki Y, Saitsu H, Shiina M, Ogata K, Watanabe S, Ohashi H, Matsumoto N, Ikegawa S
  • Journal Title: J Hum Genet Volume: 58 Issue: 6 Pages: 391-394
  • DOI: 10.1038/jhg.2013.25
  • NAID: 10031184228
  • Peer Reviewed
• [Journal Article] Identification of KLHL41 mutations implicates BTB-Kelch-mediated ubiquitination as an alternate pathway to myofibrillar disruption in nemaline myopathy (2013)
  • Author(s): Gupta V, Shiina M, Ogata K, Matsumoto N, Beggs N et al.
  • Journal Title: Am J Hum Genet Volume: 93 Issue: 6 Pages: 1108-1117
  • DOI: 10.1016/j.ajhg.2013.10.020
  • Peer Reviewed
• [Journal Article] Mutations in KLHL40 are a frequent cause of severe autosomal-recessive nemaline myopathy (2013)
  • Author(s): Ravenscroft G, Ogata K, Shiina M, Matsumoto N, Laing NG et al.
  • Journal Title: Am J Hum Genet Volume: 93 Issue: 1 Pages: 6-18
  • DOI: 10.1016/j.ajhg.2013.05.004
  • Peer Reviewed
• [Journal Article] De Novo Mutations in GNAO1, Encoding a Gαo Subunit of Heterotrimeric G Proteins, Cause Epileptic Encephalopathy. (2013)
  • Author(s): Nakamura, K., et al.,
  • Journal Title: Am. J. Hum. Genet. Volume: 93 Issue: 3 Pages: 496-505
  • DOI: 10.1016/j.ajhg.2013.07.014
  • Peer Reviewed
• [Journal Article] De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (2013)
  • Author(s): Saitsu H, Nishimura T, Muramatsu K, Kodera H, Kumada S, Sugai K, Kasai-Yoshida E, Sawaura N, Nishida H, Hoshino A, Ryujin F, Yoshioka S, Nishiyama K, Kondo Y, Tsurusaki Y, Nakashima M, Miyake N, Arakawa H, Kato M, Mizushima, Matsumoto N
  • Journal Title: Nat Genet Volume: 45 Issue: 4 Pages: 445-449
  • DOI: 10.1038/ng.2562
  • Peer Reviewed
• [Journal Article] Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. (2013)
  • Author(s): Daisuke Kurotaki et al.
  • Journal Title: Blood Volume: 121 Issue: 10 Pages: 1839-1849
  • DOI: 10.1182/blood-2012-06-437863
  • Peer Reviewed
• [Journal Article] Whole genome sequencing in patients with retinitis pigmentosa reveals pathogenic DNA structural changes and NEK2 as a new disease gene (2013)
  • Author(s): Nishiguchi KM, Tearle RG, Liu YP, Oh EC, Miyake N, Benaglio P, Harper S, Koskiniemi-Kuendig H, Venturini G, Sharon D, Koenekoop RK, Nakamura M, Kondo M, Ueno S, Yasuma TR, Beckmann JS, Ikegawa S, Matsumoto N, Terasaki H, Berson EL, Katsanis N, Rivolta C
  • Journal Title: Proc Natl Acad Sci U S A Volume: 110 Issue: 40 Pages: 16139-16144
  • DOI: 10.1073/pnas.1308243110
  • Peer Reviewed
• [Journal Article] MLL2 and KDM6A mutations in patients with Kabuki syndrome. (2013)
  • Author(s): Miyake N*, Koshimizu E, Okamoto N, Mizuno S, Ogata T,at all
  • Journal Title: Am J Med Genet A Volume: 161 Issue: 9 Pages: 2234-2243
  • DOI: 10.1002/ajmg.a.36072
  • Peer Reviewed
• [Journal Article] The USP21 short variant (USP21SV) lacking NES, located mostly in the nucleus in vivo, activates transcription by deubiquitylating ubH2A in vitro (2013)
  • Author(s): Okuda H, Ohdan H, Nakayama M, Koseki H, Nakagawa T, Ito T.
  • Journal Title: PLoS One Volume: 8 Issue: 11 Pages: 1-9
  • DOI: 10.1371/journal.pone.0079813
  • NAID: 120006986685
  • Peer Reviewed
• [Journal Article] A virtual-system coupled multicanonical molecular dynamics simulation : Principles and applications to free-energy landscape of protein-protein interaction with an all-atom model in explicit solvent (2013)
  • Author(s): J. Higo, K. Umezawa, H. Nakamura
  • Journal Title: Journal of Chemical Physics Volume: 138 Issue: 18 Pages: 184106-184106
  • DOI: 10.1063/1.4803468
  • Peer Reviewed / Open Access
• [Journal Article] LigandBox: A database for 3D structures of chemical compounds (2013)
  • Author(s): Takeshi Kawabata, Yusuke Sugihara, Yoshifumi Fukunishi, Haruki Nakamura
  • Journal Title: BIOPHYSICS Volume: 9 Issue: 0 Pages: 113-121
  • DOI: 10.2142/biophysics.9.113
  • NAID: 130003366038
  • ISSN: 1349-2942
  • Peer Reviewed / Open Access
• [Journal Article] Exhaustive comparison and classification of ligand-binding surfaces in proteins (2013)
  • Author(s): Murakami Y, Kinoshita K, Kinjo AR, Nakamura H
  • Journal Title: Protein Science Volume: 22 Issue: 10 Pages: 1379-1391
  • DOI: 10.1002/pro.2329
  • Peer Reviewed / Open Access
• [Journal Article] Molecular dynamics simulations of a double-stranded DNA in an explicit solvent model with zero-dipole summation method (2013)
  • Author(s): Arakawa T, Kamiya N, Nakamura H, Fukuda I
  • Journal Title: PLoS ONE Volume: 8 Issue: 10 Pages: e76606-e76606
  • DOI: 10.1371/journal.pone.0076606
  • Peer Reviewed / Open Access
• [Journal Article] Vitamin K2 covalently binds to Bak and induces Bak-mediated apoptosis. (2013)
  • Author(s): Karasawa S, Azuma M, Kasama T, Sakamoto S, Kabe Y, Imai T, Yamaguchi Y, Miyazawa K, Handa H
  • Journal Title: Mol Pharmacol Volume: 83 Issue: 3 Pages: 613-620
  • DOI: 10.1124/mol.112.082602
  • Peer Reviewed
• [Journal Article] NYC4, the rice ortholog of Arabidopsis THF1, is involved in the degradation of chlorophyll-protein complexes during leaf senescence. (2013)
  • Author(s): Yamatani, H.
  • Journal Title: Plant J. Volume: 74 Issue: 4 Pages: 652-662
  • DOI: 10.1111/tpj.12154
  • Peer Reviewed
• [Journal Article] Application of zero-dipole summation method to molecular dynamics (2013)
  • Author(s): Narutoshi Kamiya
  • Journal Title: Chem. Phys. Lett. Volume: 568-569 Pages: 26-32
  • DOI: 10.1016/j.cplett.2013.03.014
  • Peer Reviewed
• [Journal Article] NF-E2 p45 activates genes involved in the regulation of platelet function (2013)
  • Author(s): Fujita, R.
  • Journal Title: Molecular and Cellular Biology Volume: 印刷中
  • Peer Reviewed
• [Journal Article] KDM6A point mutations cause Kabuki syndrome (2012)
  • Author(s): Miyake N, Mizuno S, Okamoto N, Ohashi H, Shiina M, Ogata K, Tsurusaki Y, Nakashima M, Saitsu H, *Matsumoto N (*: co-corresponding)
  • Journal Title: Hum Mut Volume: 34(1):108-110 Issue: 1 Pages: 108-110
  • DOI: 10.1002/humu.22229
  • Peer Reviewed
• [Journal Article] Systematic changes to the apparent diffusion tensor of in vivo rat brain measured with an oscillating-gradient spin-echo sequence. (2012)
  • Author(s): Kershaw J, Leuze C, Aoki I, Obata I, Kanno I, Ito H, Yamaguchi Y, Handa H.
  • Journal Title: Neuroimage. Volume: 70 Pages: 10-20
  • DOI: 10.1016/j.neuroimage.2012.12.036
  • Peer Reviewed
• [Journal Article] Identification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a novel target of Bisphenol A. (2012)
  • Author(s): Ito, Y., Ito, T., Karasawa, S., Enomoto, T., Nashimoto, A., Hase, Y., Sakamoto, S., Ito, T., Mimori, T., Matsumoto, Y., Yamaguchi, Y., Handa, H.
  • Journal Title: PLos ONE Volume: 7(12) Issue: 12 Pages: e50481-e50481
  • DOI: 10.1371/journal.pone.0050481
  • Peer Reviewed
• [Journal Article] DSIF restricts NF-kappa B signaling by coordinating elongation with mRNA Processing of negative feedback genes (2012)
  • Author(s): Diamant, G.
  • Journal Title: Cell Reports Volume: 2 Issue: 4 Pages: 722-731
  • DOI: 10.1016/j.celrep.2012.08.041
  • Peer Reviewed
• [Journal Article] Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond (2012)
  • Author(s): Yamaguchi, Y.
  • Journal Title: Biochim. Biophys. Acta Volume: 1829 Issue: 1 Pages: 98-104
  • DOI: 10.1016/j.bbagrm.2012.11.007
  • Peer Reviewed
• [Journal Article] Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity. (2012)
  • Author(s): Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA, Vidal M, Bernstein BE, Koseki H.
  • Journal Title: PLoS Genet. Volume: 8 Issue: 7 Pages: e1002774-e1002774
  • DOI: 10.1371/journal.pgen.1002774
  • NAID: 120006985569
  • Peer Reviewed
• [Journal Article] Histone Monoubiquitylation Position Determines Specificity and Direction of Enzymatic Cross-talk with Histone Methyltransferases Dot1L and PRC2. (2012)
  • Author(s): Whitcomb, S.J., Fierz, B., McGinty, R.K., Holt, M., Ito, T., Muir, T.W., and Allis, C.D.
  • Journal Title: J Biol Chem Volume: 287 Issue: 28 Pages: 23718-23725
  • DOI: 10.1074/jbc.m112.361824
  • Peer Reviewed
• [Journal Article] Rapid detection of gene mutations responsible for non-syndromic aortic aneurysm and dissection using two different methods : resequencing microarray technology and next-generation sequencing (2012)
  • Author(s): Sakai H, Suzuki S, Mizuguchi T, Imoto K, Yamashita Y, Doi H, Kikuchi M, Tsurusaki Y, Saitsu H, Miyake N, Masuda M, Matsumoto N
  • Journal Title: Hum Genet Volume: 131巻 Issue: 4 Pages: 591-599
  • DOI: 10.1007/s00439-011-1105-7
  • Peer Reviewed
• [Journal Article] A family of oculofaciocardiodental syndrome(OFCD) with a novel BCOR mutation and genomic rearrangements involving NHS (2012)
  • Author(s): Kondo Y, Saitsu H, Miyamoto T, Nishiyama K, Tsurusaki Y, Doi H, Miyake N, Ryoo NK, Kim JH, Yu YS, Matsumoto N
  • Journal Title: J Hum Genet Volume: 57巻 Issue: 3 Pages: 197-201
  • DOI: 10.1038/jhg.2012.4
  • NAID: 10030712110
  • Peer Reviewed
• [Journal Article] Missense mutations in the DNA-binding/dimerization domain of NFIX cause Sotos-like features (2012)
  • Author(s): Yoneda Y, Saitsu H, Touyama M, Makita Y, Miyamoto A, Hamada K, Kurotaki N, Tomita H, Nishiyama K, Tsurusaki Y, Doi H, Miyake N, Ogata K, Naritomi K, Matsumoto N
  • Journal Title: J Hum Genet Volume: 57巻 Issue: 3 Pages: 207-211
  • DOI: 10.1038/jhg.2012.7
  • NAID: 10030712151
  • Peer Reviewed
• [Journal Article] A girl with early-onset epileptic encephalopathy associated with microdeletion involving CDKL5 (2012)
  • Author(s): *Saitsu H et al.
  • Journal Title: Brain Dev Volume: 34(5):364-7 Issue: 5 Pages: 364-367
  • DOI: 10.1016/j.braindev.2011.07.004
  • NAID: 10031050724
  • Peer Reviewed
• [Journal Article] Homozygous c. 14576G> A Variant of<I> RNF213</I> Predicts Early-Onset and Severe Form of Moyamoya Disease (2012)
  • Author(s): Miyatake S, Miyake N, Touho H, Nishimura-T, A, Kondo Y, Okada ; I, Tsurusaki ; Y, Doi H, Sakai H, Saitsu ; H, Shimojima K, Yamamoto T, Higurashi M, Kawahara, N, Kawauchi, H, Nagasaka, K, Okamoto N, Mori, T, Koyano S, Kuroiwa Y, Taguri M, Morita S, Matsuba S, Kure S, Matsumoto N
  • Journal Title: Neurology Volume: 78(11) Issue: 11 Pages: 803-10
  • DOI: 10.1212/wnl.0b013e318249f71f
  • Peer Reviewed
• [Journal Article] Identification of a novel in-frame de novo mutation in SPTAN1 in intellectual disability and pontocerebellar atrophy (2012)
  • Author(s): Hamdan F, Saitsu H (Co-first Author) et al.
  • Journal Title: Eur J Hum Genet Volume: 20(7):796-800 Issue: 7 Pages: 796-800
  • DOI: 10.1038/ejhg.2011.271
  • Peer Reviewed
• [Journal Article] Association of genomic deletions in the STXBP1 gene with Ohtahara syndrome (2012)
  • Author(s): *Saitsu H et al.
  • Journal Title: Clinical Genetics Volume: 81(4):399-402 Issue: 4 Pages: 86-90
  • DOI: 10.1111/j.1399-0004.2011.01733.x
  • Peer Reviewed
• [Journal Article] Neurodevelopmental features in 2q23.1 microdeletion syndrome: Report of a new patient with intractable seizures and review of literature (2012)
  • Author(s): Motobayashi, M.
  • Journal Title: Am. J. Med. Genet. Part A Volume: 158 Issue: 4 Pages: 861-868
  • DOI: 10.1002/ajmg.a.35235
  • Peer Reviewed
• [Journal Article] Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome (2012)
  • Author(s): Tsurusaki Y, Okamoto N, Ohashi H, Kosho T, Imai Y, Hibi-Ko Y, Kaname T, Naritomi K, Kawame H, Wakui K, Fukushima Y, Homma T, Kato M, Hiraki Y, Yamagata T, Yano S, Mizuno S, Sakazume S, Ishii T, Nagai T, Shiina M, Ogata K, Ohta T, Niikawa N, Miyatake S, Okada I, Mizuguchi T, Doi H, Saitsu H, Miyake N, Matsumoto N
  • Journal Title: Nat Genet Volume: 44 Issue: 4 Pages: 376-378
  • DOI: 10.1038/ng.2219
  • Peer Reviewed
• [Journal Article] Contiguous deletion of SLC6A8 and BAP31 in a patient with severe dystonia and sensorineural deafness (2012)
  • Author(s): Osaka, H.
  • Journal Title: Mol. Genet. Metab. Volume: 106 Issue: 1 Pages: 43-47
  • DOI: 10.1016/j.ymgme.2012.02.018
  • Peer Reviewed
• [Journal Article] Early onset West syndrome with severe hypomyelination and coloboma-like optic discs in a girl with SPTAN1 mutation (2012)
  • Author(s): Writzl K,…Saitsu H.
  • Journal Title: Epilepsia Volume: 53(6):e106-10 Issue: 6
  • DOI: 10.1111/j.1528-1167.2012.03437.x
  • Peer Reviewed
• [Journal Article] Whole exome sequencing identifies KCNQ2 mutations in Ohtahara syndrome (2012)
  • Author(s): *Saitsu H et al.
  • Journal Title: Ann Neurol Volume: 72(2):298-300 Issue: 2 Pages: 298-300
  • DOI: 10.1002/ana.23620
  • Peer Reviewed
• [Journal Article] Diffuse central hypomyelination presenting as4H syndrome caused by compound heterozygous mutations in POLR3A encoding the catalytic subunit of polymerase III. (2012)
  • Author(s): Terao Y, Saitsu H, Segawa M, Kondo Y, Sakamoto K, Matsumoto N et al.
  • Journal Title: J Neurol Sci Volume: 320(1-2) Issue: 1-2 Pages: 102-5
  • DOI: 10.1016/j.jns.2012.07.005
  • Peer Reviewed
• [Journal Article] CASK aberrations in male patients with Ohtahara syndrome and cerebellar hypoplasia (2012)
  • Author(s): *Saitsu H et al.
  • Journal Title: Epilepsia Volume: 53(8):1441-1449 Issue: 8 Pages: 1441-1449
  • DOI: 10.1111/j.1528-1167.2012.03548.x
  • Peer Reviewed
• [Journal Article] PAPSS2 mutations cause autosomal recessive brachyolmia (2012)
  • Author(s): Miyake N^<#>, Elcioglu NH^<#> (# denotes equal contribution), Iida A, Isguven P, Dai J, Murakami N, Takamura K, Cho T-J, Kim O-H, Nagai T, Ohashi H, Nishimura G, Matsumoto N, Ikegawa S
  • Journal Title: J Med Genet Volume: 49(8): 533-538 Issue: 8 Pages: 533-538
  • DOI: 10.1136/jmedgenet-2012-101039
  • Peer Reviewed
• [Journal Article] A novel SACS mutation in a Japanese family with atypical phenotype of autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) (2012)
  • Author(s): Miyatake, S.
  • Journal Title: Intern. Med. Volume: 51 Pages: 2221-2226
  • Peer Reviewed
• [Journal Article] A DYNC1H1 mutation causes a dominant spinal muscular atrophy with lower extremity. (2012)
  • Author(s): Tsurusaki Y, Saitoh S, Tomizawa K, Sudo A, Asahina N, Shiraishi H, Ito J, Tanaka H, Doi H, Saitsu H, Miyake N, Matsumoto N.
  • Journal Title: Neurogenetics. Volume: 13 Issue: 4 Pages: 327-332
  • DOI: 10.1007/s10048-012-0337-6
  • Peer Reviewed
• [Journal Article] Simple and Accurate Scheme to Compute Electrostatic Interactions: Zero-dipole Summation Technique for Molecular System and Application to Bulk Water. (2012)
  • Author(s): Ikuo Fukuda, Narutoshi Kamiya, Yasushige Yonezawa, Haruki Nakamura
  • Journal Title: Journal of Chemical Physics Volume: 137 Issue: 5 Pages: 54314-54314
  • DOI: 10.1063/1.4739789
  • NAID: 120005647641
  • Peer Reviewed
• [Journal Article] Non-Ewald methods : Theory and Applications to Molecular Systems (2012)
  • Author(s): Fukuda I, Nakamura H
  • Journal Title: Biophysical Reviews Volume: 4 Issue: 3 Pages: 161-170
  • DOI: 10.1007/s12551-012-0089-4
  • Peer Reviewed
• [Journal Article] De Novo and Inherited Mutations in COL4A2, Encoding the Type IV Collagen alpha2 Chain Cause Porencephaly (2011)
  • Author(s): Yoneda Y, et al.
  • Journal Title: Am J Hum Genet Volume: 90 Issue: 1 Pages: 86-90
  • DOI: 10.1016/j.ajhg.2011.11.016
  • Peer Reviewed
• [Presentation] GAF1 とその相互作用因子によるジベレリン生合成酵素遺伝転写制御（優秀発表賞受賞） (2017)
  • Author(s): 勝部隆義，伊藤岳，深澤壽太郎，高橋陽介
  • Organizer: 第74回中国四国植物学会
  • Place of Presentation: 高知大学（高知県高知市）
  • Year and Date: 2017-05-14
• [Presentation] ホメオドメインタンパク質によるジベレリン生合成遺伝子の転写制御機構の解析 (2017)
  • Author(s): 中村駿志，深澤壽太郎，高橋陽介
  • Organizer: 第74回中国四国植物学会
  • Place of Presentation: 高知大学（高知県高知市）
  • Year and Date: 2017-05-13
• [Presentation] ジベレリンによるシロイヌナズナの花成制御（優秀発表賞受賞） (2017)
  • Author(s): 大橋由紀，髙橋竜平，伊藤岳，深澤壽太郎，高橋陽介
  • Organizer: 第74回中国四国植物学会
  • Place of Presentation: 高知大学（高知県高知市）
  • Year and Date: 2017-05-13
• [Presentation] DELLA を介したジベレリンとジャスモン酸のクロストーク制御 (2017)
  • Author(s): 森 亮太，藤井麻耶，伊藤 岳，深澤壽太郎，高橋陽介
  • Organizer: 第74回中国四国植物学会
  • Place of Presentation: 高知大学（高知県高知市）
  • Year and Date: 2017-05-13
• [Presentation] Search for anti-leukemic drugs targeting the transcription factor Runx1 by INTENDD (2017)
  • Author(s): Shiina M, Baba S, Uchiyama A, Okada C, Tanaka T, Ikeda K, Kawakita S, Matsuzaki T, Komatsu H, Hosoda M, Ogata K
  • Organizer: The 137th Annual Meeting of the Pharmaceutical Society of Japan, 3rd International Symposium for Medicinal Sciences
  • Place of Presentation: 仙台国際センター・東北大学川内北キャンパス(宮城県仙台市)
  • Year and Date: 2017-03-24
  • Int'l Joint Research / Invited
• [Presentation] ジベレリン信号伝達におけるDELLA-GAF1複合体による新たな標的遺伝子の制御 (2017)
  • Author(s): 深澤壽太郎、大橋由紀、森亮太、高橋陽介
  • Organizer: 日本植物生理学会 第58回年会
  • Place of Presentation: 鹿児島大学（鹿児島県鹿児島市）
  • Year and Date: 2017-03-17
• [Presentation] 細胞分化における核内アクチンの機能解析 (2017)
  • Author(s): 横山吟司, 山本浩志, 山崎祥他, 十川久美子, 徳永万喜洋, 原田昌彦
  • Organizer: 日本農芸化学会2017年度大会
  • Place of Presentation: 京都女子大学（京都府京都市）
  • Year and Date: 2017-03-17
• [Presentation] 抗炎症薬サリチル酸が示す生体内作用メカニズムの解析 (2017)
  • Author(s): 坂本 聡、Gupta Vipul、劉 舒捷、安藤秀樹、舘野峻平、金子裕生、湯上真人、石井亮平、濡木 理、山口雄輝、半田 宏
  • Organizer: 日本化学会第97春季年会
  • Place of Presentation: 慶應義塾大学（神奈川県横浜市）
  • Year and Date: 2017-03-16
• [Presentation] ＲＮＡポリメラーゼⅡ転写産物の長さを決める３’末端プロセシングの制御メカニズムの解明 (2017)
  • Author(s): 瑞慶覧 安里、舘野 峻平、山本 淳一、山口 雄輝
  • Organizer: 新学術領域研究「転写サイクル」冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ(千葉県一宮町)
  • Year and Date: 2017-01-30
• [Presentation] マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析 (2017)
  • Author(s): 鈴木 翔子、柴田 紘孝、山口 雄輝
  • Organizer: 新学術領域研究「転写サイクル」冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ(千葉県一宮町)
  • Year and Date: 2017-01-30
• [Presentation] E3ユビキチンリガーゼCRBNの細胞内局在が免疫調整薬IMiDsの薬効に及ぼす影響 (2017)
  • Author(s): 徳山 遥香、片山 美樹、山口 雄輝
  • Organizer: 新学術領域研究「転写サイクル」冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ(千葉県一宮町)
  • Year and Date: 2017-01-30
• [Presentation] ターゲット因子の解析を基盤とする生物活性物質が示す作用機構の解明 (2017)
  • Author(s): 坂本 聡、山口 雄輝、半田 宏
  • Organizer: 新学術領域研究「転写サイクル」冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ(千葉県一宮町)
  • Year and Date: 2017-01-30
• [Presentation] DNA損傷時に誘導される転写制御の生理的意義とTLPの役割 (2017)
  • Author(s): 鈴木 秀文、前田 亮、木村 宏、浦 聖恵、山口 雄輝、田村 隆明
  • Organizer: 新学術領域研究「転写サイクル」冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ(千葉県一宮町)
  • Year and Date: 2017-01-30
• [Presentation] 多発性骨髄腫における Pomalidomide 標的因子の網羅的探索 (2017)
  • Author(s): 舘野 峻平 、飯田 緑 、藤井 聡 、佐倉 絵里、山口 雄輝
  • Organizer: 新学術領域研究「転写サイクル」冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ(千葉県一宮町)
  • Year and Date: 2017-01-30
• [Presentation] ウェットとドライの真の融合を目指して (2017)
  • Author(s): 藤井 聡
  • Organizer: 冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ（千葉県長生郡）
  • Year and Date: 2017-01-30
• [Presentation] 転写因子とヒストン修飾の関連性を提示するためのデータベース構築 (2017)
  • Author(s): 飯田 緑、藤井 聡
  • Organizer: 冬の若手ワークショップ2017
  • Place of Presentation: 一宮シーサイドオーツカ（千葉県長生郡）
  • Year and Date: 2017-01-30
• [Presentation] Multi-modal Dynamic Cross Correlation (mDCC) 法の開発と転写因子- DNA 複合体におけ る動的相関ネットワークの解析 (2017)
  • Author(s): 笠原 浩太
  • Organizer: 名古屋大学 IGER セミナー
  • Place of Presentation: 名古屋大学(愛知県名古屋市)
• [Presentation] 天然変性領域による転写制御の分子機構 (2017)
  • Author(s): 笠原 浩太
  • Organizer: 第5回 関西4私大 生命科学シンポジウム
  • Place of Presentation: 関西学院会館光の間(兵庫県西宮市)
• [Presentation] １分子イメージングとFRAPによるINO80クロマチン再構成複合体の核内動態解析 (2016)
  • Author(s): 伊藤由馬, 原田昌彦, 木村宏, 十川久美子, 徳永万喜洋
  • Organizer: 第8回「光塾」
  • Place of Presentation: 東京工業大学すずかけ台キャンパス（神奈川県横浜市）
  • Year and Date: 2016-12-17
• [Presentation] How Pol II termination and 3' processing sites are precisely determined in higher eukaryotes.高等真核生物においてPol IIの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか (2016)
  • Author(s): Ari Zukeran, Junichi Yamamoto, and Yuki Yamaguchi
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-11-30
  • Invited
• [Presentation] NELFを中心としたポリ(A)付加部位選択のメカニズム (2016)
  • Author(s): 瑞慶覧 安里、山本 淳一、山口 雄輝
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-11-30
• [Presentation] パートナー因子によるEts1のコンフォーメーション分布の変化と活性制御機構の解析 (2016)
  • Author(s): 内山晃子，椎名政昭，浜田恵輔，馬場しほ，岡田千佳子，鈴木香絵，佐藤 光，緒方一博
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜 (神奈川県横浜市)
  • Year and Date: 2016-11-30
• [Presentation] 転写因子Ets1の天然変性領域のリン酸化によるDNA結合制御機構の速度論的解析 (2016)
  • Author(s): 椎名政昭，笠原浩太，肥後順一，馬場しほ，内山晃子，岡田千佳子，浜田恵輔，佐藤 光，中村春木，緒方一博
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜 (神奈川県横浜市)
  • Year and Date: 2016-11-30
• [Presentation] Single-molecule imaging of the INO80 chromatin remodeling complex in the living cell nucleus (2016)
  • Author(s): 伊藤 由馬, 原田 昌彦, 十川久美子, 徳永万喜洋
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] CLIP-170 phosphorylation mediates repositioning of microtubule-organizing center during T cell activation (2016)
  • Author(s): 林 偉銘, 伊藤 由馬, 徳永万喜洋, 十川久美子
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] Single molecule imaging and quantitative analysis of nucleolar-localized protein dynamics (2016)
  • Author(s): 松本 大輝, 伊藤 由馬, 斉藤 典子，徳永万喜洋, 十川久美子
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] Super-resolution analysis of microtubule dynamics on T cell activation (2016)
  • Author(s): 史 恒宇, 伊藤 由馬, 林 偉銘， 十川久美子, 徳永万喜洋
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] Fluorescence recovery after photobleaching(FRAP) analysis of INO80 chromatin remodeling complex (2016)
  • Author(s): 磯垣 翼, 伊藤 由馬, 市川 翔太, 木村 宏, 原田 昌彦, 十川久美子, 徳永万喜洋
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] PDLIM2-interacting protein MKRN2 functions as a novel E3 ligase for p65 subunit of NF-κB (2016)
  • Author(s): 申 纂暎, 伊藤 由馬, 徳永万喜洋, 田中 貴志, 十川久美子
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] Live cell imaging and quantitative analysis of anti-inflammatory protein PDLIM2 activation upon LPS stimulation (2016)
  • Author(s): 市川 翔太, 伊藤 由馬, 田中 貴志, 徳永万喜洋, 十川久美子
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] Quantitative image analysis of dynamics of promoter-proximal pausing related proteins (2016)
  • Author(s): 國見 慎之介, 伊藤 由馬, 山口 雄輝, 十川久美子, 徳永万喜洋
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場（ 茨城県つくば市）
  • Year and Date: 2016-11-25
• [Presentation] Flexible docking between cyclin-dependent kinase 2 and its inhibitor using multicanonical MD (2016)
  • Author(s): Gert-Jan Bekker, Narutoshi Kamiya, Mitsugu Araki, Yasushi Okuno, Haruki Nakamura
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場(茨城県つくば市)
  • Year and Date: 2016-11-25
• [Presentation] 分子シミュレーションにおける静電相互作用計算法:零多重極子法の理論と実際 (2016)
  • Author(s): 福田 育夫, Wang Han, 神谷 成敏, 笠原 浩太, 寺田 透, 櫻庭 俊, 中村 春木
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場(茨城県つくば市)
  • Year and Date: 2016-11-25
• [Presentation] Oct4の2つのDNA結合サブドメインを結ぶ柔軟なlinker領域の自由エネルギー地形 (2016)
  • Author(s): 速水 智教、高田 彰二、中村 春木、肥後 順一
  • Organizer: 第54回日本生物物理学会年会
  • Place of Presentation: つくば国際会議場(茨城県つくば市)
  • Year and Date: 2016-11-25
• [Presentation] 巨大生体分子の長時間 MD シミュレーションの開発と生体分子の構造機能相関の解明 (2016)
  • Author(s): 鷹野 優、Neetha Mohan、草鹿 あゆみ、川端 猛、笠原 浩太、真下 忠彰、神谷 成敏、中村 春木
  • Organizer: 第8回「学際計算科学による新たな知の発展・統合・創出」 シンポジウム
  • Place of Presentation: 筑波大学計算科学研究センター(茨城県つくば市)
  • Year and Date: 2016-10-17
• [Presentation] 高等真核生物においてPOL Ⅱの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか (2016)
  • Author(s): 瑞慶覧 安里、長谷川 冴妃子、館野 峻平、山本 淳一、山口 雄輝
  • Organizer: 新学術領域研究「転写サイクル」班会議2016
  • Place of Presentation: 松島一の坊（宮城県宮城郡）
  • Year and Date: 2016-09-05
• [Presentation] ＴＢＰ類似因子ＴＬＰによるＤＮＡ損傷応答時の転写抑制と細胞死誘導機構の解析 (2016)
  • Author(s): 鈴木 秀文、前田 亮、浦 聖恵、木村 宏、山口 雄輝、田村 隆明
  • Organizer: 新学術領域研究「転写サイクル」班会議2016
  • Place of Presentation: 松島一の坊（宮城県宮城郡）
  • Year and Date: 2016-09-05
• [Presentation] NELFを中心としたポリ(A)付加部位選択のメカニズム (2016)
  • Author(s): 瑞慶覧 安里、館野 峻平、山本 淳一、山口 雄輝
  • Organizer: 新学術領域研究「転写サイクル」班会議2016
  • Place of Presentation: 松島一の坊（宮城県宮城郡）
  • Year and Date: 2016-09-05
• [Presentation] 公共ChIP-Seqデータの統合解析による転写制御の解析 (2016)
  • Author(s): 藤井 聡
  • Organizer: 転写サイクル合同班会議2016
  • Place of Presentation: 松島一の坊(宮城県宮城郡)
  • Year and Date: 2016-09-05
• [Presentation] 転写産物とPolIIエンリッチメントプロファイリングによるDecapping exoribonuclease (Dom3z) の機能解析 (2016)
  • Author(s): 飯田 緑、磯部 智康、山口 雄輝、藤井 聡
  • Organizer: 転写サイクル合同班会議2016
  • Place of Presentation: 松島一の坊(宮城県宮城郡)
  • Year and Date: 2016-09-05
• [Presentation] 計算・情報科学による 転写サイクルにおける情報変換機構の解明 (2016)
  • Author(s): 笠原 浩太、Neetha Mohan、中村 春木
  • Organizer: 転写サイクル合同班会議2016
  • Place of Presentation: 松島一の坊(宮城県宮城郡)
  • Year and Date: 2016-09-05
• [Presentation] Molecular behavior of a higher-order complex of multiple transcription factors on enhancer site upon phosphorylation (2016)
  • Author(s): Ogata K, Shiina M, Kasahara K, Higo J, Hamada K, Nakamura H
  • Organizer: 6th International Conference on Structural Biology (Structural Biology 2016)
  • Place of Presentation: Hilton New Orleans Airport Hotel (米国ルイジアナ州)
  • Year and Date: 2016-08-22
  • Int'l Joint Research / Invited
• [Presentation] DELLA-GAF1/IDD2 complex regulates gibberellin homeostasis and signaling (2016)
  • Author(s): Fukazawa, J., Ito, T., Takahashi, Y.
  • Organizer: 22nd International Plant Growth Substances Association Conference
  • Place of Presentation: トロント（カナダ）
  • Year and Date: 2016-06-21
  • Int'l Joint Research
• [Presentation] CRBNに対するサリドマイド光学異性体の結合基盤解析 (2016)
  • Author(s): 坂本 聡、伊藤 拓水、森 智行、安藤 秀樹、山口 雄輝、箱嶋 敏雄、半田 宏
  • Organizer: 日本ケミカルバイオロジー学会第11回年会
  • Place of Presentation: 京都テルサ（京都府京都市）
  • Year and Date: 2016-06-15
• [Presentation] リガンド依存的ユビキチンリガーゼＣＲＢＮの制御機構 (2016)
  • Author(s): 伊藤 拓水、朝妻 知子、山本 淳一 安藤 秀樹、佐藤 智美、山口 雄輝、半田 宏
  • Organizer: 日本ケミカルバイオロジー学会第11回年会
  • Place of Presentation: 京都テルサ（京都府京都市）
  • Year and Date: 2016-06-15
• [Presentation] p53 C末端ドメインのアセチル化およびヒスチジンの荷電状態の変化がその立体構造集団に及ぼす影響 (2016)
  • Author(s): 飯田 慎仁, 牟田 寛弥, 後藤 祐児, 北條 裕信, 中村 春木, 肥後 順一
  • Organizer: 第16回日本蛋白質科学会年会
  • Place of Presentation: 福岡国際会議場(福岡県福岡市)
  • Year and Date: 2016-06-07
• [Presentation] 天然変性領域の過渡的な相互作用による転写制御の分子機構 (2016)
  • Author(s): 笠原 浩太、椎名 政昭、肥後 順一、緒方 一博、中村 春木
  • Organizer: 第16回日本蛋白質科学会年会
  • Place of Presentation: 福岡国際会議場(福岡県福岡市)
  • Year and Date: 2016-06-07
• [Presentation] Insights Derived from Molecular Dynamics Simulations into the Subunit Assembly and Clamp Motions of Thermococcus kodakarensis RNA Polymerase (2016)
  • Author(s): Neetha Mohan, Kota Kasahara, Akira Hirata, Haruki Nakamura
  • Organizer: 第16回日本蛋白質科学会年会
  • Place of Presentation: 福岡国際会議場(福岡県福岡市)
  • Year and Date: 2016-06-07
• [Presentation] An efficient new methodology for path elucidation and binding free energy calculation (2016)
  • Author(s): Gert-Jan Bekker, Narutoshi Kamiya, Haruki Nakamura
  • Organizer: 第16回日本蛋白質科学会年会
  • Place of Presentation: 福岡国際会議場(福岡県福岡市)
  • Year and Date: 2016-06-07
• [Presentation] Molecular mechanism for modulation of a multiple transcription factor complex formed on enhancer site up on phosphorylation (2016)
  • Author(s): Ogata K, Shiina M, Kasahara K, Higo J, Hamada K, Nakamura H
  • Organizer: 5th International Conference and Exhibition on Metabolomics
  • Place of Presentation: ハイアットリージェンシー大阪（大阪府大阪市）
  • Year and Date: 2016-05-16
  • Int'l Joint Research / Invited
• [Presentation] GAF1複合体によるGA生合成酵素遺伝子の転写抑制機構の解析（優秀発表賞受賞） (2016)
  • Author(s): 勝部隆義, 伊藤岳, 深澤壽太郎, 高橋陽介
  • Organizer: 第73回 中国四国植物学会
  • Place of Presentation: 米子コンベンションセンター（島根県）
  • Year and Date: 2016-05-15
• [Presentation] ジベレリンとオーキシンによる茎部の伸長制御機構の解析（優秀発表賞受賞） (2016)
  • Author(s): 伊東裕太, 伊藤岳, 高橋陽介
  • Organizer: 第73回 中国四国植物学会
  • Place of Presentation: 米子コンベンションセンター（島根県）
  • Year and Date: 2016-05-15
• [Presentation] DELLA-GAF1複合体によるジベレリン信号伝達の制御機構 (2016)
  • Author(s): 深澤壽太郎、高橋竜平、藤井麻弥、高橋陽介
  • Organizer: 第73回 中国四国植物学会
  • Place of Presentation: 米子コンベンションセンター（島根県）
  • Year and Date: 2016-05-15
• [Presentation] DELLA-GAF1複合体によるジベレリン信号伝達の制御機構 (2016)
  • Author(s): 深澤 壽太郎、高橋 竜平、藤井 麻弥、高橋 陽介
  • Organizer: 第73回中国四国植物学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
  • Year and Date: 2016-05-15
• [Presentation] ジベレリンとオーキシンによる茎部の伸長制御機構の解析 (2016)
  • Author(s): 伊東 裕太, 伊藤 岳, 高橋 陽介
  • Organizer: 第73回中国四国植物学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
  • Year and Date: 2016-05-14
• [Presentation] GAF1複合体によるGA生合成酵素遺伝子の転写抑制機構の解析 (2016)
  • Author(s): 勝部 隆義, 伊藤 岳, 深澤 壽太郎, 高橋 陽介
  • Organizer: 第73回中国四国植物学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
  • Year and Date: 2016-05-14
• [Presentation] カルシウム依存性タンパク質リン酸化酵素NtCDPK1の自己リン酸化による機能制御の解析 (2016)
  • Author(s): 伊藤 岳, 石田 さらみ, 高橋 陽介
  • Organizer: 第57回日本植物生理学会
  • Place of Presentation: 岩手大学（岩手県岩手市）
  • Year and Date: 2016-03-19
• [Presentation] ヒストンH2Aのリン酸化と癌化 (2016)
  • Author(s): 伊藤 敬
  • Organizer: 生物多様性コロキウム
  • Place of Presentation: 京都大学（京都府京都市）
  • Year and Date: 2016-03-14
• [Presentation] BigData to Knowledge to Wisdom (2016)
  • Author(s): Haruki Nakamura
  • Organizer: Data Sharing Symposium
  • Place of Presentation: 一橋大学一橋講堂（東京都千代田区）
  • Year and Date: 2016-02-29
  • Int'l Joint Research / Invited
• [Presentation] ヒストン翻訳後修飾と癌化 (2016)
  • Author(s): 伊藤 敬
  • Organizer: Science Medical Frontier Forum
  • Place of Presentation: 御茶ノ水ソラシティカンファレンスセンター（東京都千代田区）
  • Year and Date: 2016-02-08
• [Presentation] 多発性骨髄腫におけるPomalidomide標的因子の網羅的探索 (2016)
  • Author(s): 舘野 峻平、飯田 緑、藤井 聡、山口 雄輝
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] 新規抗がん剤の作用機構の解明 (2016)
  • Author(s): 佐倉 絵里、舘野 峻平、山口 雄輝
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] PolⅡ複合体をモデルとしたタンパク質間相互作用の実験系の評価 (2016)
  • Author(s): 新垣 貴之、徳山 遥香、山口 雄輝
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] NELFを中心としたRNAの品質管理のメカニズム (2016)
  • Author(s): 瑞慶覧 安里、山本 淳一、磯部 智康、山口 雄輝
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] サリドマイド標的タンパク質CRBNの相互作用因子の探索 (2016)
  • Author(s): 徳山 遥香、新垣 貴之、山口雄輝
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析 (2016)
  • Author(s): 鈴木 翔子、柴田 紘孝、山口 雄輝
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] サリドマイドの多様な薬理作用の分子メカニズム (2016)
  • Author(s): 山口 雄輝、伊藤 巧水、山本 淳一、半田 宏
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] snRNA3'末端プロセシング因子インテグレーターの構造・機能解析 (2016)
  • Author(s): 外山 黛、荻原 裕里、Thiengtrong, Benjarat、山口 雄輝
  • Organizer: 冬の若手ワークショップ2016
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-05
• [Presentation] Decapping exoribonuclease(DOX:Dom3z)の転写制御における機能解析 (2016)
  • Author(s): 飯田緑、磯部智康、山口雄輝、藤井聡
  • Organizer: 冬の若手ワークショップ2015
  • Place of Presentation: ホテル清渓（山梨県南都留郡）
  • Year and Date: 2016-02-04
• [Presentation] Computational approaches to analyze and predict protein-protein interactions (2016)
  • Author(s): Haruki Nakamura
  • Organizer: IPR International Workshop
  • Place of Presentation: 大阪大学蛋白質研究所 (大阪府吹田市)
  • Year and Date: 2016-02-02
  • Int'l Joint Research / Invited
• [Presentation] 細胞核内アクチンフィラメントのゲノム機能への関与 (2016)
  • Author(s): 山崎祥他，山本浩二，十川久美子，徳永万喜洋，原田昌彦
  • Organizer: 第33回染色体ワークショップ・第14回核ダイナミクス研究会
  • Place of Presentation: 一の坊（宮城県宮城郡）
  • Year and Date: 2016-01-12
• [Presentation] 細胞分化における核内アクチンの機能解析 (2016)
  • Author(s): 山本浩二，山崎祥他，十川久美子，徳永万喜洋，原田昌彦
  • Organizer: 第33回染色体ワークショップ・第14回核ダイナミクス研究会
  • Place of Presentation: 一の坊（宮城県宮城郡）
  • Year and Date: 2016-01-12
• [Presentation] Somatic mutation in Sturge Weber syndrome (2016)
  • Author(s): Naomichi Matsumoto
  • Organizer: The 11th Asisan & Oceanian Epilepsy Congress(AOEC)
  • Place of Presentation: Hong Kong Convention & Exhibition Centre（香港）
  • Int'l Joint Research / Invited
• [Presentation] Rare variants in human diseases (2016)
  • Author(s): Naomichi Matsumoto
  • Organizer: International Symposium on Genomic Medicine 2016
  • Place of Presentation: Samsung Medical Center（韓国ソウル市）
  • Int'l Joint Research / Invited
• [Presentation] Mendelian Exome in Japan (2016)
  • Author(s): Naomichi Matsumoto
  • Organizer: LMCE2016, Symposium 13
  • Place of Presentation: The-K Hotel（韓国ソウル市）
  • Int'l Joint Research / Invited
• [Presentation] Rare variants in human diseases (2016)
  • Author(s): Naomichi Matsumoto
  • Organizer: The 2016 Annual Meeting of the Chinese Society of Medical Genetics (CSMG)
  • Place of Presentation: 中国杭州市
  • Int'l Joint Research / Invited
• [Presentation] New Methods for Structure Guided Drug Development (2016)
  • Author(s): Haruki Nakamura
  • Organizer: JCUP VII
  • Place of Presentation: 大手町サンスカイルーム朝日生命大手町ビル(東京都千代田区)
  • Int'l Joint Research / Invited
• [Presentation] Computational Approaches to Coupled Folding and Binding in Protein-Protein Interactions (2016)
  • Author(s): Haruki Nakamura
  • Organizer: 21st Biophysics Conference
  • Place of Presentation: Hsinchu (台湾)
  • Int'l Joint Research / Invited
• [Presentation] Computational analysis on electrostatic properties of protein and Protein-Protein Interactions (2016)
  • Author(s): Haruki Nakamura
  • Organizer: Asia Pacific Protein Association (APPA), IPR International Seminar
  • Place of Presentation: 大阪大学蛋白質研究所(大阪府吹田市)
  • Int'l Joint Research / Invited
• [Presentation] バイオインフォマティクスの世界へようこそ (2016)
  • Author(s): 飯田 緑
  • Organizer: 第3回LaMer 特別講演会
  • Place of Presentation: 愛媛大学(愛媛県松山市)
• [Presentation] Computational Approaches to Coupled Folding and Binding in Protein-Protein Interactions (2016)
  • Author(s): Haruki Nakamura
  • Organizer: The 11th International Symposium of the Protein Society of Thailand
  • Place of Presentation: Bangkok (タイ)
  • Int'l Joint Research / Invited
• [Presentation] Computational Approaches to Protein Interactions (2016)
  • Author(s): Haruki Nakamura
  • Organizer: Japan-Slovenia JSPS Bilateral scientific exchange
  • Place of Presentation: Koper（スロベニア）
  • Int'l Joint Research / Invited
• [Presentation] １分子顕微鏡で観る免疫細胞活性化の初期過程 (2015)
  • Author(s): 十川久美子
  • Organizer: 宇都宮大学 オプト－バイオシンポジウム
  • Place of Presentation: 宇都宮大学（栃木県宇都宮市）
  • Year and Date: 2015-12-21
  • Invited
• [Presentation] 最先端テクノロジーによる疾患ゲノム解析 (2015)
  • Author(s): 松本 直通
  • Organizer: 第1回日本産婦人科遺伝診療学会学術講演会・教育講演
  • Place of Presentation: 長崎ブリックホール（長崎県長崎市）
  • Year and Date: 2015-12-18
  • Invited
• [Presentation] Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads (2015)
  • Author(s): Satoshi Sakamoto, Yuki Yamaguchi, Takumi Ito, Hiroshi Handa
  • Organizer: PACIFCHEM2015
  • Place of Presentation: ホノルル（アメリカ）
  • Year and Date: 2015-12-17
  • Int'l Joint Research
• [Presentation] Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs) (2015)
  • Author(s): Satoshi Sakamoto, Takumi Ito, Yuki Yamaguchi, Hideki Ando, Hiroshi Handa
  • Organizer: PACIFCHEM2015
  • Place of Presentation: ホノルル（アメリカ）
  • Year and Date: 2015-12-16
  • Int'l Joint Research
• [Presentation] ヒト疾患とrare variants (2015)
  • Author(s): 松本 直通
  • Organizer: 第23回食細胞機能異常症研究会
  • Place of Presentation: 東京慈恵医科大学（東京都港区）
  • Year and Date: 2015-12-12
  • Invited
• [Presentation] Computational approach to find a specific interaction among many IDR relating fuzzy complexes (2015)
  • Author(s): Haruki Nakamura
  • Organizer: International Symposium on Structure and Folding of Disease Related Proteins
  • Place of Presentation: ソウル（韓国）
  • Year and Date: 2015-12-04
  • Int'l Joint Research / Invited
• [Presentation] 多発性骨髄腫に対するポマリドマイドの標的因子の網羅的探索 (2015)
  • Author(s): 館野 俊平、飯田 緑、藤井 聡、山口 雄輝
  • Organizer: 第３８回日本分子生物学会年会
  • Place of Presentation: 神戸ポートアイランド（兵庫県神戸市）
  • Year and Date: 2015-12-03
• [Presentation] EPR1の新規転写抑制モチーフの機能解析 (2015)
  • Author(s): 伊藤 岳, 岡村 僚太, 佐久間 哲史, 山本 卓, 高橋 陽介
  • Organizer: 第38回日本分子生物学会
  • Place of Presentation: 神戸ポートアイランド（兵庫県神戸市）
  • Year and Date: 2015-12-03
• [Presentation] ATP依存的なクロマチンリモデリング因子でCBPによるヒストンアセチル化を刺激し転写を亢進する (2015)
  • Author(s): 土井口 真康 、中川 武弥 、伊藤 敬
  • Organizer: 第３８回日本分子生物学会年会
  • Place of Presentation: 神戸ポートピアホテル（兵庫県神戸市）
  • Year and Date: 2015-12-01
• [Presentation] Dzip3はマウス胚性幹細胞において染色体の高次構造を調整することによって発生に関する遺伝子を制御する (2015)
  • Author(s): 井上 大嗣、里 龍晴、相原 仁、水崎 博文、土井口 真康、東 美樹、宮西 隆幸、奥田 晶彦、中川武弥、伊藤 敬
  • Organizer: 第３８回日本分子生物学会年会
  • Place of Presentation: ポートピアホテル（兵庫県神戸市）
  • Year and Date: 2015-12-01
• [Presentation] Ets1とRunx1のエンハンサー上での立体的な位置関係と協調性 (2015)
  • Author(s): 内山 晃子，椎名 政昭，浜田 恵輔，豊後 泰子，嶋村 麻利子，緒方 一博
  • Organizer: BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会）
  • Place of Presentation: 神戸ポートアイランド（兵庫県神戸市）
  • Year and Date: 2015-12-01
• [Presentation] Kinetic characterization of a DNA binding activity of the transcription factor Ets1 and its regulation by phosphorylation in an intrinsically disordered region (2015)
  • Author(s): Shiina M, Kasahara K, Higo J, Baba S, Hamada K, Uchiyama A, Suzuki K, Sato K, Nakamura H, Ogata K
  • Organizer: BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会）
  • Place of Presentation: 神戸ポートアイランド（兵庫県神戸市）
  • Year and Date: 2015-12-01
• [Presentation] 分子構造に基づく転写因子Nuclear factor (erythroid-derived2)-like2(Nrf2)の抗酸化剤応答配列認識機構の解析 (2015)
  • Author(s): 鈴木 香絵，椎名 政昭，浜田 恵輔，石川 涼平，金井 達哉，豊後 泰子，岡田 千佳子，馬場 しほ，鈴木 隆史，太田 力，山本 雅之，緒方 一博
  • Organizer: BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会）
  • Place of Presentation: 神戸ポートアイランド（兵庫県神戸市）
  • Year and Date: 2015-12-01
• [Presentation] Somatic mutations in the MTOR gene cause focal cortical dysplasia type IIb (2015)
  • Author(s): Naomichi Matsumoto
  • Organizer: Biochemistry and Molecular Biology (BMB) 2015
  • Place of Presentation: 神戸ポートピアホテル（兵庫県神戸市）
  • Year and Date: 2015-12-01
  • Int'l Joint Research / Invited
• [Presentation] 遺伝子解析におけるドロップレットディジタルPCRの活用 (2015)
  • Author(s): 松本直通
  • Organizer: 第38回日本分子生物学会年会(第88回日本生化学会大会)BMB2015, ランチョンセミナー
  • Place of Presentation: 神戸ポートピアホテル（兵庫県神戸市）
  • Year and Date: 2015-12-01
  • Invited
• [Presentation] A specific interaction among many fuzzy complexes regulated by phosphorylation: Molecular simulation approach (2015)
  • Author(s): Haruki Nakamura
  • Organizer: RSC/IPR Joint Symposium “Protein Structure and Function”
  • Place of Presentation: キャンベラ（オーストラリア）
  • Year and Date: 2015-11-14
  • Int'l Joint Research / Invited
• [Presentation] Pol IIの転写伸長と運命決定制御のメカニズム (2015)
  • Author(s): 山口 雄輝
  • Organizer: 第２回北陸エピジェネティクス研究会
  • Place of Presentation: 富山大学（富山県富山市）
  • Year and Date: 2015-11-10
  • Invited
• [Presentation] Rare variants in human diseases (2015)
  • Author(s): Naomichi Matsumoto
  • Organizer: University of Split Lecture
  • Place of Presentation: スプリット（クロアチア）
  • Year and Date: 2015-11-09
  • Invited
• [Presentation] Next Generation Sequencing Dissecting Human “Genetic” Diseases (2015)
  • Author(s): Naomichi Matsumoto
  • Organizer: The VI Croatian Congress of Human Genetics
  • Place of Presentation: スプリット（クロアチア）
  • Year and Date: 2015-11-06
  • Int'l Joint Research / Invited
• [Presentation] ジベレリン信号伝達におけるDELLA-GAF1複合体の標的遺伝子の探索 (2015)
  • Author(s): 深澤 壽太郎、高橋 竜平、藤井 麻弥、三島 由佳、高橋 陽介
  • Organizer: 第50回植物化学調節学会大会
  • Place of Presentation: 東京大学（東京都文京区）
  • Year and Date: 2015-10-25
• [Presentation] 低頻度体細胞モザイク変異が惹起するヒト疾患 (2015)
  • Author(s): 松本 直通
  • Organizer: 日本人類遺伝学会第60回大会
  • Place of Presentation: 京王プラザホテル（東京都新宿区）
  • Year and Date: 2015-10-16
• [Presentation] クロマチン動態制御におけるアクチン関連タンパク質Arp4の核内ダイナミクス (2015)
  • Author(s): 伊藤由馬，木村宏，原田昌彦，十川久美子，徳永万喜洋
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] Yeast two hybridおよび定量イメージング解析によるPDLIM2相互作用タンパク質の同定 (2015)
  • Author(s): 申纂暎，伊藤由馬，十川久美子，田中貴志，徳永万喜洋
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] リポ多糖刺激における炎症抑制タンパク質PDLIM2活性化のイメージング定量解析 (2015)
  • Author(s): 市川翔太，伊藤由馬，田中貴志，徳永万喜洋，十川久美子
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] CLIP170 phosphorylation mediates repositioning of microtubule-organizing center during T cell activation (2015)
  • Author(s): 林偉銘，伊藤由馬，徳永万喜洋，十川久美子
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] 蛍光褪色回復法によるINO80クロマチンリモデリング複合体の核内動態解析 (2015)
  • Author(s): 伊藤由馬，磯垣翼，木村宏，原田昌彦，十川久美子，徳永万喜洋
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] １分子イメージングによる転写伸長因子NELFとDSIFのダイナミクス定量解析 (2015)
  • Author(s): 池田大地，伊藤由馬，徳永万喜洋，十川久美子
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] 転写因子Ets1天然変性領域のリン酸化によるDNA認識阻害メカニズムの検討 (2015)
  • Author(s): 笠原浩太、肥後順一、椎名政昭、緒方一博、中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] EMDBとPDBデータの形状類似検索：Omokage検索 (2015)
  • Author(s): 鈴木博文, 川端猛, 中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] ヘムの構造歪みが酸化還元電位に与える影響の計算科学的研究 (2015)
  • Author(s): 今田康博, 中村春木, 鷹野優
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] 抗体CDR-H3ループ領域の立体構造予測 (2015)
  • Author(s): 西上博士, Gert-Jan Bekker, 神谷成敏, 肥後順一, 中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] 天然変性領域であるp53C末端ドメインの構造と物性にアセチル化が及ぼす影響 (2015)
  • Author(s): 飯田慎仁, 北條裕信, 中村春木, 肥後順一
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] On the convergence of binding free-energy landscape calculation by improved virtual-system coupled adaptive umbrella sampling (2015)
  • Author(s): Bhaskar Dasgupta, 肥後順一, 中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] A novel method to determine the optimal unbinding path between receptor and ligand using advanced molecular dynamics simulation (2015)
  • Author(s): Gert-Jan Bekker, 神谷成敏, 中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] 低解像度密度マップへの複数のサブユニットのあてはめ計算-実験情報による拘束の利用- (2015)
  • Author(s): 川端猛, 鈴木博文, 中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] Molecular Tailoring Approach法による蛋白質二次構造内に働く相互作用の量子化学的研究 (2015)
  • Author(s): 草鹿あゆみ, 中村春木, 鷹野優
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] 分子シミュレーションにおける静電相互作用計算のための新規非エバルト法 (2015)
  • Author(s): 福田育夫, 神谷成敏, Han Wang, 笠原浩太、中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] Interaction of two subunits of D/L hetero dimer with catalytic subunits in archaeal RNA polymerase: Insights from MD simulations (2015)
  • Author(s): Neetha Mohan, 笠原浩太、平田章、中村春木
  • Organizer: 第53回日本生物物理学会年会
  • Place of Presentation: 金沢大学角間キャンパス（石川県金沢市）
  • Year and Date: 2015-09-13
• [Presentation] Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes (2015)
  • Author(s): Yuki Yamaguchi and Junichi Yamamoto
  • Organizer: MECHANISM OF EUKARYOTIC TRANSCRIPTION
  • Place of Presentation: Cold Spring Harbor（アメリカ）
  • Year and Date: 2015-08-27
  • Int'l Joint Research
• [Presentation] 転写伸張因子DSIFのCTRを介した転写制御機構の解析 (2015)
  • Author(s): 磯部 智康、山口 雄輝
  • Organizer: 転写サイクル班会議2015
  • Place of Presentation: ホテル暖香園（静岡県伊東市）ホテル暖香園
  • Year and Date: 2015-08-05
• [Presentation] NELFを中心としたmRNAの品質管理のメカニズム (2015)
  • Author(s): 瑞慶覧 安里、山本 淳一、磯部 智康、山口 雄輝
  • Organizer: 転写サイクル班会議2015
  • Place of Presentation: ホテル暖香園（静岡県伊東市）
  • Year and Date: 2015-08-05
• [Presentation] 転写伸長段階の制御メカニズム：新たな制御因子の探索 (2015)
  • Author(s): 山口 雄輝、磯部 智康、曹 青福、山本 淳一
  • Organizer: 転写サイクル班会議2015
  • Place of Presentation: ホテル暖香園（静岡県伊東市）
  • Year and Date: 2015-08-04
• [Presentation] 分子シミュレーションから解き明かす転写因子Ets1のDNA結合調節機構 (2015)
  • Author(s): 笠原浩太、Neetha Mohan、肥後順一、福田育夫、中村春木
  • Organizer: 転写サイクル合同班会議2015
  • Place of Presentation: ホテル暖香園（静岡県伊東市）
  • Year and Date: 2015-08-03
• [Presentation] 転写制御に関係するヒストン修飾パターンの解析 (2015)
  • Author(s): 藤井 聡、西山 晃、田村 智彦
  • Organizer: 転写サイクル合同班会議2015
  • Place of Presentation: ホテル暖香園（静岡県伊東市）
  • Year and Date: 2015-08-03
• [Presentation] RNA polymerase IIのプロファイル解析 (2015)
  • Author(s): 飯田 緑、磯部 智康、山口 雄輝、藤井 聡
  • Organizer: 転写サイクル合同班会議2015
  • Place of Presentation: ホテル暖香園（静岡県伊東市）
  • Year and Date: 2015-08-03
• [Presentation] 遺伝性疾患における話題提供 (2015)
  • Author(s): 松本 直通
  • Organizer: 第22回日本遺伝子診療学会大会・プレシジョン医療と診断情報の質保証
  • Place of Presentation: かながわ労働プラザ（神奈川県横浜市）
  • Year and Date: 2015-07-19
  • Invited
• [Presentation] ヒト疾患とrare variants (2015)
  • Author(s): 松本 直通
  • Organizer: 第33回内分泌代謝学サマーセミナー・続・内分泌至上主義・シンポジスト
  • Place of Presentation: 柳川藩主立花邸（福岡県柳川市）
  • Year and Date: 2015-07-09
  • Invited
• [Presentation] Computational Approaches to Coupled Folding and Binding in Protein-Protein Interactions (2015)
  • Author(s): Haruki Nakamura
  • Organizer: 19th KPPS (Korean Peptide Protein Symposium) Symposium
  • Place of Presentation: 泰安郡（韓国）
  • Year and Date: 2015-07-07
  • Int'l Joint Research / Invited
• [Presentation] ヘムの構造歪みが酸化還元電位に与える影響の計算科学的研究 (2015)
  • Author(s): 今田康博, 中村春木, 鷹野優
  • Organizer: 第15回日本蛋白質科学会年会
  • Place of Presentation: あわぎんホール（徳島県徳島市）
  • Year and Date: 2015-06-24
• [Presentation] p53蛋白質C末端天然変性領域の構造探索 (2015)
  • Author(s): 飯田慎仁, 神谷成敏, 北條裕信, 中村春木, 肥後順一
  • Organizer: 第15回日本蛋白質科学会年会
  • Place of Presentation: あわぎんホール（徳島県徳島市）
  • Year and Date: 2015-06-24
• [Presentation] 転写因子Ets1とパートナー転写因子の協調的結合によるDNA結合活性制御機構の計算科学的検討 (2015)
  • Author(s): 笠原浩太, 福田育夫, 中村春木
  • Organizer: 第15回日本蛋白質科学会年会
  • Place of Presentation: あわぎんホール（徳島県徳島市）
  • Year and Date: 2015-06-24
• [Presentation] FRET法とRAMD法を用いた核内受容体PPARγのリガンド結合に関する実験・理論的研究 (2015)
  • Author(s): 神谷成敏, Gert-Jan Bekker, 白木琢磨, 中村春木
  • Organizer: 第15回日本蛋白質科学会年会
  • Place of Presentation: あわぎんホール（徳島県徳島市）
  • Year and Date: 2015-06-24
• [Presentation] Molecular Tailoring Approachによるタンパク質の二次構造に働く相互作用の量子化学的解析 (2015)
  • Author(s): 鷹野優, 草鹿あゆみ, 中村春木
  • Organizer: 第15回日本蛋白質科学会年会
  • Place of Presentation: あわぎんホール（徳島県徳島市）
  • Year and Date: 2015-06-24
• [Presentation] HOMCOSサーバを用いた複合体立体構造の進化的保存性の解析 (2015)
  • Author(s): 川端猛, 中村春木
  • Organizer: 第15回日本蛋白質科学会年会
  • Place of Presentation: あわぎんホール（徳島県徳島市）
  • Year and Date: 2015-06-24
• [Presentation] EMDBとPDBを対象とした形状類似性検索：Omokage検索 (2015)
  • Author(s): 鈴木博文, 川端猛, 中村春木
  • Organizer: 第15回日本蛋白質科学会年会
  • Place of Presentation: あわぎんホール（徳島県徳島市）
  • Year and Date: 2015-06-24
• [Presentation] 全エクソーム解析データの様々な活用法 (2015)
  • Author(s): 松本 直通
  • Organizer: 2015アジレントゲノミクスフォーラム・招聘講演
  • Place of Presentation: ヒューリックホール浅草橋（東京都台東区）
  • Year and Date: 2015-06-16
  • Invited
• [Presentation] IMiDs標的タンパク質CRBNの生化学的解析 (2015)
  • Author(s): 坂本 聡、伊藤 拓水、安藤 秀樹、山口 雄輝、半田 宏
  • Organizer: 日本ケミカルバイオロジー学会第10回年会
  • Place of Presentation: 東北大学（宮城県仙台市）
  • Year and Date: 2015-06-10
• [Presentation] Deep sequencing detects very low-grade somatic mosaicism in the unaffected mother of siblings with nemaline myopathy (2015)
  • Author(s): Naomichi Matsumoto, Eriko Koshimizu, Satoko Miyatake
  • Organizer: European Human Genetics Conference 2015
  • Place of Presentation: グラスゴー（イギリス）
  • Year and Date: 2015-06-06
  • Int'l Joint Research
• [Presentation] Prediction of protein-protein and protein-ligand interactions, and application to drug discovery (2015)
  • Author(s): Haruki Nakamura
  • Organizer: The 9th Asian Biophysics Association Symposium (ABA2015)
  • Place of Presentation: 瀋陽（中国）
  • Year and Date: 2015-05-10
  • Int'l Joint Research / Invited
• [Presentation] 遺伝性疾患の次世代シーケンス解析 (2015)
  • Author(s): 松本 直通
  • Organizer: 産総研Computational Biology Research Center (CBRC)セミナー
  • Place of Presentation: 産総研・臨海副都心センター別館（東京都江東区）
  • Year and Date: 2015-04-23
  • Invited
• [Presentation] Computational analysis on electrostatic properties of proteins and their assembly (2015)
  • Author(s): Haruki Nakamura
  • Organizer: The first trilateral workshop for frontier protein studies
  • Place of Presentation: 北京（中国）
  • Year and Date: 2015-04-23
  • Int'l Joint Research / Invited
• [Presentation] アフィニティビーズを利用した生物活性物質標的タンパク質の単離・同定・評価 (2015)
  • Author(s): 坂本 聡、山口 雄輝、半田 宏
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学（兵庫県神戸市）
  • Year and Date: 2015-03-28
• [Presentation] DELLA-GAF1/IDD2複合体によるGA信号伝達とフィードバック制御機構 (2015)
  • Author(s): 深澤壽太郎、高橋陽介
  • Organizer: 第56回日本植物生理学会
  • Place of Presentation: 東京農業大学（東京都世田谷区）
  • Year and Date: 2015-03-18
• [Presentation] EPR1の新奇転写抑制モチーフの機能解析 (2015)
  • Author(s): 伊藤岳、高橋陽介
  • Organizer: 第56回日本植物生理学会
  • Place of Presentation: 東京農業大学（東京都世田谷区）
  • Year and Date: 2015-03-17
• [Presentation] 転写因子Ets1の天然変性領域によるDNA認識調節メカニズムに関する計算化学的検討 (2015)
  • Author(s): 笠原浩太
  • Organizer: 第3回天然変性蛋白質計算科学セミナー
  • Place of Presentation: 御殿場高原時之栖（静岡県御殿場市）
  • Year and Date: 2015-03-11
• [Presentation] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes (2015)
  • Author(s): 山本 淳一、半田 宏、山口 雄輝
  • Organizer: 冬の若手ワークショップ2015
  • Place of Presentation: ホテル松本楼（群馬県渋川市）
  • Year and Date: 2015-02-06
• [Presentation] 転写伸長因子DSIFのリン酸化の転写伸長反応への寄与の解析 (2015)
  • Author(s): 磯部 智康、千葉 国俊、山口 雄輝
  • Organizer: 冬の若手ワークショップ2015
  • Place of Presentation: ホテル松本楼（群馬県渋川市）
  • Year and Date: 2015-02-06
• [Presentation] 核内アクチンフィラメントの転写制御への関与とその分子機構の解析 (2014)
  • Author(s): 山崎 祥他, 山本 浩二、十川 久美子, 徳永 万喜洋, 原田 昌彦
  • Organizer: 第32回染色体ワークショップ・第13回核ダイナミクス研究会
  • Place of Presentation: 安芸グランドホテル(広島県廿日市市)
  • Year and Date: 2014-12-15 – 2014-12-17
• [Presentation] 個別化医療を進めるために (2014)
  • Author(s): 松本 直道
  • Organizer: 日本遺伝子診療学会：遺伝子診断・検査技術推進フォーラム公開シンポジウム2014）
  • Place of Presentation: コクヨホール（東京都港区）
  • Year and Date: 2014-12-12
• [Presentation] Coffin-Siris症候群の新規遺伝子探索 (2014)
  • Author(s): 松本 直道
  • Organizer: NCNP（精神・神経疾患研究開発費（後藤班）平成26年度報告会
  • Place of Presentation: ＮＣＮＰ（東京都小平市）
  • Year and Date: 2014-12-09
  • Invited
• [Presentation] TUBB4A変異による先天性白質形成不全症 (2014)
  • Author(s): 松本 直道
  • Organizer: NCNP（精神・神経疾患研究開発費（佐々木班）平成26年度報告会
  • Place of Presentation: ＮＣＮＰ（東京都小平市）
  • Year and Date: 2014-11-30
  • Invited
• [Presentation] “Congenital intellectual disability syndromes arising from mutations of epigenetic regulators”in the symposium for epigenetic dysregulation and disease (2014)
  • Author(s): 松本 直道
  • Organizer: The 37th annual meeting of the molecular biology society of Japan
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市）
  • Year and Date: 2014-11-27
• [Presentation] 発癌誘導に関与するヒストンH2A変異体の解析 (2014)
  • Author(s): 相原 仁, 水崎 博文, 中川 武弥, 伊藤 敬
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市）
  • Year and Date: 2014-11-27
• [Presentation] ジベレリン信号伝達に関与するカルシウム依存性タンパク質リン酸化酵素NtCDPK1の自己リン酸化による機能制御の解析 (2014)
  • Author(s): 伊藤岳、高橋陽介
  • Organizer: 第37回日本分子生物学会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Kinetic characterization of a DNA binding activity of the transcription factor Ets1 and its regulation by phosphorylation at an intrinsically disordered region (2014)
  • Author(s): Shiina M, Hamada K, Bungo-Inoue T, Shimamura M, Uchiyama A, Baba S, Sato K, Suzuki K, Yamamoto M, Ogata K
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市)
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Orientation of Ets1 and Runx1 binding sites on enhancers and their cooperative regulation (2014)
  • Author(s): Uchiyama A, Shiina M, Hamada K, Bungo T, Shimamura M, Ogata K
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市)
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Structure-based analysis for DNA recognition mechanism of the Nrf2-containing transcription factor heterodimer (2014)
  • Author(s): Suzuki K, Shiina M, Hamada K, Bungo T, Okada C, Baba S, Ohta T, Ogata K
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市)
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Microtubules Instability and Dynamics Mediated by CLIP-170 in T Cells (2014)
  • Author(s): Wei Ming Lim,伊藤 由馬, 十川 久美子, 徳永 万喜洋
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Live cell single-molecule imaging of T cell receptor and microcluster with planar lipid bilayers (2014)
  • Author(s): 伊藤 由馬, 十川 久美子, 徳永 万喜洋
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] E3ユビキチンリガーゼの基質認識レセプター CRBNとポマリドマイド依存的な基質Aiolosの生化学的解析 (2014)
  • Author(s): 片山 美樹,伊藤 拓水,安藤 秀樹,山口 雄輝,半田 宏
  • Organizer: 第３７回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-11-25
• [Presentation] Histone H2A Thr 120 phosphorylation results in cancer via up regulation of Cyclin D1 (2014)
  • Author(s): Hirofumi Mizusaki, Hitoshi Aihara, Takashi Ito
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市）
  • Year and Date: 2014-11-25
• [Presentation] Dzip3はマウスES細胞において分化に関与する様々な遺伝子を調節する (2014)
  • Author(s): 井上 大嗣, 相原 仁, 水崎 博文, 土井口 真康, 中山 敏幸, 中川 武弥, 伊藤 敬
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市）
  • Year and Date: 2014-11-25
• [Presentation] Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes (2014)
  • Author(s): 山口雄輝、山本淳一
  • Organizer: 転写サイクル国際シンポジウム2014
  • Place of Presentation: 東工大蔵前会館（東京都目黒区）
  • Year and Date: 2014-11-24
• [Presentation] 人類遺伝学研究におけるデータベースの重要性 (2014)
  • Author(s): 松本 直道
  • Organizer: 日本人類遺伝学会第59回大会・松本直通・NPGランチョンセミナー
  • Place of Presentation: タワーホール船堀・東京（東京都江戸川区）
  • Year and Date: 2014-11-22
• [Presentation] 次世代シーケンサーを用いた染色体・ゲノム構造異常解析 (2014)
  • Author(s): 松本 直道
  • Organizer: 日本人類遺伝学会第59回大会
  • Place of Presentation: タワーホール船堀・東京（東京都江戸川区）
  • Year and Date: 2014-11-21
  • Invited
• [Presentation] 次世代シーケンサーによる遺伝子解析 (2014)
  • Author(s): 松本 直道
  • Organizer: 第56回日本先天代謝異常学会総会
  • Place of Presentation: 江陽グランドホテル・仙台（宮城県仙台市）
  • Year and Date: 2014-11-14
• [Presentation] 次世代シーケンサーの活用法 (2014)
  • Author(s): 松本 直道
  • Organizer: 第17回胎児遺伝子診断研究会
  • Place of Presentation: 長崎ハウステンボス（長崎県佐世保市）
  • Year and Date: 2014-11-07
• [Presentation] Zero-dipole summation法を用いたエンハンソソーム制御メカニズムの分子動力学的解析 (2014)
  • Author(s): 笠原浩太、福田育夫
  • Organizer: 第1回「京」を中核とするHPCIシステム利用研究課題成果報告会
  • Place of Presentation: コクヨホール（東京都港区）
  • Year and Date: 2014-10-31
• [Presentation] DELLA-GAF1複合体によるGA信号伝達とフィードバック制御機構の解析 (2014)
  • Author(s): 深澤壽太郎、高橋陽介
  • Organizer: 第49回植物化学調節学会
  • Place of Presentation: 京都大学（京都府京都市）
  • Year and Date: 2014-10-19
• [Presentation] ヒストンシャペロンNap1の構造解析 (2014)
  • Author(s): 浜田恵輔，椎名政昭，中島理沙，斎藤 誠，伊藤 敬，緒方一博
  • Organizer: 第87回日本生化学会大会
  • Place of Presentation: 国立京都国際会館（京都府京都市）
  • Year and Date: 2014-10-15 – 2014-10-18
• [Presentation] Analysis of the function of nuclear actin in cell differentiation (2014)
  • Author(s): 山本 浩志, 山崎 祥他, 十川 久美子, 徳永 万喜洋, 原田 昌彦
  • Organizer: 第87回日本生化学会大会
  • Place of Presentation: 国立京都国際会館・グランドプリンスホテル京都(京都府京都市）
  • Year and Date: 2014-10-15 – 2014-10-18
• [Presentation] Functional regulation of the dynamics of actin in the nucleus (2014)
  • Author(s): 山崎 祥他, 十川 久美子, 徳永 万喜洋, 原田 昌彦
  • Organizer: 第87回日本生化学会大会
  • Place of Presentation: 国立京都国際会館・グランドプリンスホテル京都(京都府京都市）
  • Year and Date: 2014-10-15 – 2014-10-18
• [Presentation] 分子動力学シミュレーション解析のためのMulti-modal Dynamic Cross Correlation法の開発と応用 (2014)
  • Author(s): 笠原浩太、福田育夫、中村春木
  • Organizer: 第3回生命医薬情報学連合大会
  • Place of Presentation: 仙台国際センター（宮城県仙台市）
  • Year and Date: 2014-10-02
• [Presentation] Segmentation & fitting algorithm for multiple submit fitting into a low resolution density map (2014)
  • Author(s): Takeshi Kawabata, Hirofumi Suzuki, Haruki Nakamura
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2014-09-27
• [Presentation] Theoretical analysis of molecular interactions in secondary structures of proteins (2014)
  • Author(s): Yu Takano, Ayumi Kusaka, Haruki Nakamura
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2014-09-27
• [Presentation] Contact number diffusion model for the normal mode analysis of protein structure (2014)
  • Author(s): Bhaskar Dasgupta, Kota Kasahara, Narutoshi Kamiya, Haruki Nakamura, Akira Kinjo
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2014-09-26
• [Presentation] Formation of microclusters of receptor molecules improves signal/noise ratio in cellular signal transduction (2014)
  • Author(s): 深川 暁宏, 十川 久美子, 徳永 万喜洋
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター(北海道札幌市）
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Single molecule imaging and quantitative analysis of dynamics of negative elongation factor NELF (2014)
  • Author(s): 池田 大地, 伊藤 由馬, 徳永 万喜洋, 十川 久美子
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター(北海道札幌市）
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Studies of dynamic chromatin structure and function to understand fundamentals of life (2014)
  • Author(s): 十川 久美子, 伊藤 由馬, 深川 暁宏, 原田 昌彦, 木村 宏, 徳永 万喜洋
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター(北海道札幌市）
  • Year and Date: 2014-09-25 – 2014-09-27
  • Invited
• [Presentation] The elucidation of the molecular mechanism of PDLIM2 activation (2014)
  • Author(s): 鳥山 悟, 伊藤 由馬, 田中 貴志, 徳永 万喜洋, 十川 久美子
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター(北海道札幌市）
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] A series of GECO mutants suitable for calcium imaging in a wide range of calcium concentration (2014)
  • Author(s): 大木 杜生, 伊藤 由馬, 徳永 万喜洋, 十川 久美子
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター(北海道札幌市）
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] T cell receptor on the surface of living cells changes in the dynamics inside microclusters revealed by single-molecule imaging analysis (2014)
  • Author(s): 伊藤 由馬, 十川 久美子, 徳永 万喜洋
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター(北海道札幌市）
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Free-energy landscape of C-terminal negative regulatory domain of p53 (2014)
  • Author(s): Shinji Iida, Haruki Nakamura, Junini Higo
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2014-09-25
• [Presentation] Computational study of the electronic structures of hemes in cytochrome c3 (2014)
  • Author(s): Yasuhiro Imada, Haruki Nakamura, Yu Takano
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2014-09-25
• [Presentation] Elastic properties of dynein motor domain obatined from all-atom molecular dynamics simulations in explicit water (2014)
  • Author(s): Narutoshi Kamiya, Tadaaki Mashimo, Yu Takano, Takahide Kon, Genji Kurisu, Haruki Nakamura
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2014-09-25
• [Presentation] Molecular dynamics study on cooperative binding of Ets1 and partner transcription factors on regulatory elements (2014)
  • Author(s): Kota Kasahara, Ikuo Fukuda, Haruki Nakamura
  • Organizer: 第52回日本生物物理学会年会
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2014-09-25
• [Presentation] Histone H2A Thr 120 phosphorylation results in cancer via up regulation of Cyclin D1 (2014)
  • Author(s): Hirofumi Mizusaki, Hitoshi Aihara, Takashi Ito
  • Organizer: Cold Spring Harbor Laboratory Meeting & Courses Epigenetics & Chromatin
  • Place of Presentation: コールドスプリングハーバー（アメリカ）
  • Year and Date: 2014-09-10
• [Presentation] Histone H2A Mutation Might Play Roles in Carcinogenesis (2014)
  • Author(s): Hitoshi Aihara, Hirofumi Mizusaki, Takeya Nakagawa, Takashi Ito
  • Organizer: Cold Spring Harbor Laboratory Meeting & Courses Epigenetics & Chromatin
  • Place of Presentation: コールドスプリングハーバー（アメリカ）
  • Year and Date: 2014-09-10
• [Presentation] ゲノム解析と医療--1000ドルゲノム時代を迎えて-- (2014)
  • Author(s): 松本 直道
  • Organizer: KOBE内分泌・代謝スキルアップセミナー特別講演
  • Place of Presentation: ホテルクラウンパレス神戸（兵庫県神戸市）
  • Year and Date: 2014-08-23
• [Presentation] A new non-Ewald scheme for molecular dynamics simulation and its application to a free energy landscape for protein-protein interaction (2014)
  • Author(s): Haruki Nakamura
  • Organizer: 2nd International Conference on Computational Science and Engineering (ICCSE 2014)
  • Place of Presentation: ホーチミン（ベトナム）
  • Year and Date: 2014-08-23
  • Invited
• [Presentation] ヒト発生・発達異常の分子探索と診断法の開発 (2014)
  • Author(s): 松本 直道
  • Organizer: 文部科学省イノベーションシステム整備事業先端融合領域イノベーション創出拠点形成プログラム「翻訳後修飾プロテオミクス医療研究拠点の形成」第5回公開シンポジウム
  • Place of Presentation: 県民共済みなとみらいホール（神奈川県横浜市）
  • Year and Date: 2014-08-19
  • Invited
• [Presentation] 難病を解き明かすヒト全遺伝子・全ゲノム解析 (2014)
  • Author(s): 松本 直道
  • Organizer: 横浜市立大学先端医科学研究センター市民講座
  • Place of Presentation: ウイング横浜（神奈川県横浜市）
  • Year and Date: 2014-08-07
  • Invited
• [Presentation] 転写伸長因子DSIFにリン酸化依存的に相互作用する因子の機能解析 (2014)
  • Author(s): 磯部 智康、千葉 国俊、山口 雄輝
  • Organizer: 転写サイクル班会議2014
  • Place of Presentation: 慶山（山梨県笛吹市）
  • Year and Date: 2014-08-05
• [Presentation] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes (2014)
  • Author(s): 山本淳一、半田宏、山口雄輝
  • Organizer: 転写サイクル班会議2014
  • Place of Presentation: 慶山（山梨県笛吹市）
  • Year and Date: 2014-08-05
• [Presentation] 転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割 (2014)
  • Author(s): 柴田 紘孝、半田 宏、山口 雄輝
  • Organizer: 転写サイクル班会議2014
  • Place of Presentation: 慶山（山梨県笛吹市）
  • Year and Date: 2014-08-05
• [Presentation] 新規転写伸長因子ヒトRtf1が関与する転写制御の分子機構 (2014)
  • Author(s): 曹 青福、陳 業熹、半田 宏、山口 雄輝
  • Organizer: 転写サイクル班会議2014
  • Place of Presentation: 慶山（山梨県笛吹市）
  • Year and Date: 2014-08-05
• [Presentation] ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構 (2014)
  • Author(s): 山口 雄輝、山本 淳一、半田 宏
  • Organizer: 転写サイクル班会議2014
  • Place of Presentation: 慶山（山梨県笛吹市）
  • Year and Date: 2014-08-04
• [Presentation] GAF1, A DELLA INTERACTING PROTEIN, REGULATES GIBBERELLIN HOMEOSTASIS AND SIGNALING (2014)
  • Author(s): Fukazawa, J., Takahasi, Y.
  • Organizer: 25th International Conference on Arabidopsis Research
  • Place of Presentation: バンクーバー（カナダ）
  • Year and Date: 2014-07-28 – 2014-08-01
• [Presentation] 共用スパコンを用いた分子動力学シミュレーション研究 (2014)
  • Author(s): 笠原浩太
  • Organizer: 国立遺伝学研究所スーパーコンピュータユーザ会
  • Place of Presentation: 国立遺伝学研究所（静岡県三島市）
  • Year and Date: 2014-07-22
• [Presentation] Scaffold function of Ca2+-dependent protein kinase: NtCDPK1 transfers 14-3-3 to the substrate RSG after phosphorylation (2014)
  • Author(s): Ito, T., Takahashi, Y.
  • Organizer: Plant Biology 2014
  • Place of Presentation: ポートランド（アメリカ）
  • Year and Date: 2014-07-12 – 2014-07-16
• [Presentation] 遺伝性疾患のゲノム解析---1000ドルゲノム時代を迎えて--- (2014)
  • Author(s): 松本 直道
  • Organizer: がん研臨床試験・研究センター 第12回臨床研究セミナー
  • Place of Presentation: がん研究会（東京都江東区）
  • Year and Date: 2014-07-03
• [Presentation] 発達障害のゲノム解析 (2014)
  • Author(s): 松本 直道
  • Organizer: 第110回日本精神神経学会学術総会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-06-27
• [Presentation] fkcombu：2D-MCSを用いた鋳型ベースの低分子化合物ドッキング法の開発 (2014)
  • Author(s): 川端猛、中村春木
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: ワークピア横浜（神奈川県横浜市）
  • Year and Date: 2014-06-27
• [Presentation] 抗原抗体ドッキングのデコイセット評価法 (2014)
  • Author(s): 榛葉教子、神谷成敏、中村春木
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: ワークピア横浜（神奈川県横浜市）
  • Year and Date: 2014-06-26
• [Presentation] Cytochrome c3中のヘムの電子構造制御に関する計算科学的研究 (2014)
  • Author(s): 今田康博、中村春木、鷹野優
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: ワークピア横浜（神奈川県横浜市）
  • Year and Date: 2014-06-26
• [Presentation] Regulation of DNA binding of Ets1 by phosphorylation in an intrinsic disordered region (2014)
  • Author(s): 椎名政昭，浜田恵輔，井上－豊後泰子，嶋村麻利子，馬場しほ，内山晃子，鈴木香絵，タヒロフ タヒール，緒方一博
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: ワークピア横浜（神奈川県横浜市）
  • Year and Date: 2014-06-25 – 2014-06-27
  • Invited
• [Presentation] 蛋白質の二次構造形成に関わる相互作用に関する理論的研究 (2014)
  • Author(s): 鷹野優、中村春木
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: ワークピア横浜（神奈川県横浜市）
  • Year and Date: 2014-06-25
  • Invited
• [Presentation] Free-energy landscape of the C-terminal negative regulatory domain of p53 (2014)
  • Author(s): Sinji Iida, Haruki Nakamura, Junichi Higo
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: ワークピア横浜（神奈川県横浜市）
  • Year and Date: 2014-06-25
• [Presentation] 分子動力学法に基づいた新しい動的相関解析手法の開発と転写因子Ets-1-DNA結合機構解析への応用 (2014)
  • Author(s): 笠原浩太、福田育夫、中村春木
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: ワークピア横浜（神奈川県横浜市）
  • Year and Date: 2014-06-25
• [Presentation] ゲノム解析と医療：1000ドルゲノム時代を迎えて (2014)
  • Author(s): 松本 直道
  • Organizer: 藤田保健衛生大学遺伝子網羅的解析センター開所記念セミナー・特別講演
  • Place of Presentation: 藤田保健衛生大学（愛知県豊明市）
  • Year and Date: 2014-06-21
• [Presentation] New Non-Ewald Scheme for Molecular Dynamics Simulation and Application to Free Energy Calculation (2014)
  • Author(s): Haruki Nakamura
  • Organizer: Bioinformatics in Torun 2014 (BIT14)
  • Place of Presentation: Torun(Poland)
  • Year and Date: 2014-06-12
  • Invited
• [Presentation] 抗炎症薬サリチル酸の生体内作用機構の解析 (2014)
  • Author(s): 坂本 聡、Vipul Gupta、劉 舒捷、安藤 秀樹、舘野 峻平、金子 裕生、湯上 真人、石井 亮平、濡木 理、山口 雄輝、半田 宏
  • Organizer: 日本ケミカルバイオロジー学会第９回年会
  • Place of Presentation: 大阪大学（大阪府豊中市）
  • Year and Date: 2014-06-11
• [Presentation] Neurodegeneration with Brain Iron Accumulation (NBIA): 急速に広がる疾患概念 (2014)
  • Author(s): 松本 直道
  • Organizer: 第55回日本神経病理学会総会学術集会
  • Place of Presentation: 学術総合センター（東京都千代田区）
  • Year and Date: 2014-06-07
• [Presentation] ゲノム解析と医療：1000ドルゲノムシーケンス時代を迎えて (2014)
  • Author(s): 松本 直道
  • Organizer: 信州大学先鋭領域融合研究群バイオメディカル研究所設立記念講演会・記念講演会
  • Place of Presentation: 信州大学医学部（長野県松本市）
  • Year and Date: 2014-05-25
• [Presentation] ゲノム解析と医療：1000ドルゲノム時代を迎えて (2014)
  • Author(s): 松本 直道
  • Organizer: 九州大学産婦人科セミナー
  • Place of Presentation: 第二博多偕成ビルアイクレオ（福岡県福岡市）
  • Year and Date: 2014-05-21
• [Presentation] New Approach to Electrostatic Properties of Proteins and Protein-Protein Interactions (2014)
  • Author(s): Haruki Nakamura
  • Organizer: The 4th Asia Pacific Protein Association (APPA 2014)
  • Place of Presentation: 済州島（韓国）
  • Year and Date: 2014-05-18
  • Invited
• [Presentation] Molecular dynamics study on enhancer recognitions by cooperative binding of Ets1 and partner transcription factors (2014)
  • Author(s): 笠原浩太、福田育夫、中村春木
  • Organizer: The 4th Asia Pacific Protein Association (APPA 2014)
  • Place of Presentation: 済州島（韓国）
  • Year and Date: 2014-05-18
• [Presentation] 植物の新奇転写抑制モチーフ –真核生物に保存された転写抑制機構の解析 (2014)
  • Author(s): 岡村僚太、高橋陽介
  • Organizer: 第71回中国四国植物学会
  • Place of Presentation: 岡山理科大学（岡山県岡山市）
  • Year and Date: 2014-05-10
• [Presentation] 翻訳後修飾によるジベレリン信号伝達制御の解析 (2014)
  • Author(s): 三島由佳、高橋陽介
  • Organizer: 第71回中国四国植物学会
  • Place of Presentation: 岡山理科大学（岡山県岡山市）
  • Year and Date: 2014-05-10
• [Presentation] 遺伝性疾患におけるエクソーム解析の有用性 (2014)
  • Author(s): 松本 直道
  • Organizer: 第382回医学研究の基礎を語り合う集い
  • Place of Presentation: 東京慈恵医科大学（東京都港区）
  • Year and Date: 2014-04-21
• [Presentation] Next generation sequencing dissecting human genetic diseases (2014)
  • Author(s): 松本 直道
  • Organizer: The 9th Cherry Blossom Symposium
  • Place of Presentation: 横浜赤レンガ倉庫（神奈川県横浜市）
  • Year and Date: 2014-04-19
• [Presentation] 次世代シーケンサー解析のポテンシャルと小児医療 (2014)
  • Author(s): 松本 直通
  • Organizer: 第37回日本小児遺伝学会学術集会・シンポジウム
  • Place of Presentation: 名古屋市立大学桜山キャンパス(愛知県名古屋市）
  • Year and Date: 2014-04-10
• [Presentation] Quantitative imaging analysis of molecular dynamics of actin-related protein in the nucleus (2014)
  • Author(s): Yuma Ito, Naomichi Inaba, Masahiko Harata, Hiroshi Kimura, Makio Tokunaga, Kumiko Sakata-Sogawa
  • Organizer: 58th Annual Meeting of Biophysical Society
  • Place of Presentation: Moscone Center（米国カリフォルニア州）
• [Presentation] Molecular imaging analysis of regulatory mechanism of inflammatory response (2014)
  • Author(s): Yuma Ito, Jun Takimoto, Takashi Tanaka, Tsuneyasu Kaisho, Makio Tokunaga, Kumiko Sakata-Sogawa
  • Organizer: 58th Annual Meeting of Biophysical Society
  • Place of Presentation: Moscone Center（米国カリフォルニア州）
• [Presentation] 複数のChIP-Seqデータの統合解析手法の検討 (2014)
  • Author(s): 藤井 聡、西山 晃、田村 智彦
  • Organizer: 冬の若手ワークショップ2014
  • Place of Presentation: 舌切雀のお宿 磯部ガーデン（群馬県）
• [Presentation] 転写因子Ets1のDNA結合制御に関する分子シミュレーション研究 (2014)
  • Author(s): 笠原 浩太，福田 育夫，中村 春木
  • Organizer: 冬の若手ワークショップ2014
  • Place of Presentation: 舌切雀のお宿 磯部ガーデン（群馬県）
• [Presentation] Cellecta社製プール型レンチウイルスshRNAライブラリーを用いたスクリーニングデータ解析法の検討 (2014)
  • Author(s): 飯田 緑, 舘野 峻平, 山口 雄輝, 藤井 聡
  • Organizer: 冬の若手ワークショップ2014
  • Place of Presentation: 舌切雀のお宿 磯部ガーデン（群馬県）
• [Presentation] Transcriptome analysis of red seabream (Pagrus major) embryos treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (2014)
  • Author(s): M. Iida, S. Fujii, M. Uchida, H. Nakamura, Y. Kagami, S.M. Bak, E.Y. Kim, Y. Shima, H. Iwata
  • Organizer: Society of Toxicology
  • Place of Presentation: Phoenix Convention Center（米国アリゾナ州）
• [Presentation] ジベレリンの転写代謝システム及翻訳後修飾制御機構 (2014)
  • Author(s): 深澤壽太郎，森雅彦，増谷優次，宮本知佳，高橋陽介
  • Organizer: 冬の若手ワークショップ
  • Place of Presentation: 磯部ガーデン（群馬県）
• [Presentation] 植物の新奇転写抑制モチーフ –真核生物に保存された転写抑制機構の解析– (2014)
  • Author(s): 伊藤岳，岡村僚太，佐久間哲史，山本卓，高橋陽介
  • Organizer: 第55回日本植物生理学会
  • Place of Presentation: 富山大学（富山県）
• [Presentation] ジベレリン生合成酵素遺伝子 AtGA20ox2 のフィードバック制御機構の解析 (2014)
  • Author(s): 森雅彦，渡辺哲史，深沢寿太郎，伊藤岳，高橋陽介
  • Organizer: 第55回日本植物生理学会
  • Place of Presentation: 富山大学（富山県）
• [Presentation] 分子シミュレーションにおける静電相互作用計算法について： Ewald, Non-Ewald, and Zero-dipole summation (2013)
  • Author(s): 福田育夫
  • Organizer: 京阪奈計算生物物理セミナー
  • Place of Presentation: 京都大学（京都）
  • Year and Date: 2013-03-29
  • Invited
• [Presentation] ジベレリン信号伝達に関与するタンパク質リン酸化酵素NtCDPK1の自己リン酸化による機能制御の解析 (2013)
  • Author(s): 大江 翔太
  • Organizer: 第54回日本植物生理学会
  • Place of Presentation: 岡山大学（岡山）
  • Year and Date: 2013-03-22
• [Presentation] JAシグナルを負に制御するbHLH型転写因子JAM1の解析 (2013)
  • Author(s): 中田 克
  • Organizer: 第54回日本植物生理学会
  • Place of Presentation: 岡山大学（岡山）
  • Year and Date: 2013-03-22
• [Presentation] The mechanism of action of thalidomide, a drug with two faces (2013)
  • Author(s): Yamaguchi, Y.
  • Organizer: International Marine Biotechnology Symposium 2013
  • Place of Presentation: 沖縄産業支援センター（沖縄）
  • Year and Date: 2013-03-18
  • Invited
• [Presentation] Single molecule imaging in living cells and stochastic features of inter- and intra-molecular interactions. (2013)
  • Author(s): Makio Tokunaga
  • Organizer: 1st Bioscience and Biotechnology International symposium “Biomolecular assemblies from nano to micro”
  • Place of Presentation: 東京工業大学（神奈川）
  • Year and Date: 2013-01-30
  • Invited
• [Presentation] Drug Development for a GPCR with in-silico screening (2013)
  • Author(s): Haruki Nakamura
  • Organizer: Nagoya Symposium, Frontiers in Structural Physiology
  • Place of Presentation: 名古屋大学（愛知）
  • Year and Date: 2013-01-24
  • Invited
• [Presentation] Computational Prediction and Analysis of Protein-Protein Interactions: Qualitative and Quantitative Approaches (2013)
  • Author(s): Haruki Nakamura
  • Organizer: Special Seminar at Academia Sinica
  • Place of Presentation: Academia Sinica, Shanghai
  • Year and Date: 2013-01-18
  • Invited
• [Presentation] A simple non-Ewald scheme for calculating electrostatic interactions of charged particle systems: the zero-dipole summation method and the application to molecular systems (2013)
  • Author(s): 福田 育夫
  • Organizer: 2013年ハイパフォーマンスコンピューティングと計算科学シンポジウム
  • Place of Presentation: 東京工業大学（東京）
  • Year and Date: 2013-01-15
• [Presentation] GPUを利用したZero-dipole summation法による静電相互作用計算の高速化 (2013)
  • Author(s): 中村春木
  • Organizer: 2013年ハイパフォーマンスコンピューティングと計算科学シンポジウム
  • Place of Presentation: 東京工業大学（東京）
  • Year and Date: 2013-01-15
• [Presentation] A new non-Ewald scheme: The zero-dipole summation method and its applications to molecular dynamics simulations for homogeneous and inhomogeneous biomolecular systems (2013)
  • Author(s): Haruki Nakamura
  • Organizer: National Symposium on Frontiers of Biophysics, Biotechnology Bioinformatics and 37'th Annual Meeting of Indian Biophysical Society
  • Place of Presentation: University of Mumbai, India
  • Year and Date: 2013-01-14
  • Invited
• [Presentation] Prediction of protein-protein complex structures (2013)
  • Author(s): Haruki Nakamura
  • Organizer: International Conference on Biomolecular Forms and Functions
  • Place of Presentation: Indian Institute of Science Bangalore, India
  • Year and Date: 2013-01-10
  • Invited
• [Presentation] DSIF and NELF interact with Integrator and participate in 3’ processing of snRNA genes: A possible mechanism controlling the fate of Pol II (2013)
  • Author(s): Yamaguchi, Y., Yamamoto, J., and Handa, H.
  • Organizer: CSHL Meeting on Mechanisms of Eukaryotic Transcription
  • Place of Presentation: Cold Spring Harbor Laboratory（米国ニューヨーク州）
• [Presentation] The diverse pharmacological effects of thalidomide (2013)
  • Author(s): Yamaguchi, Y.
  • Organizer: BioJapan 2013 World Business Forum
  • Place of Presentation: パシフィコ横浜（神奈川県）
  • Invited
• [Presentation] １分子研究が明かす動的でエントロピー的な分子間・分子内相互作用 (2013)
  • Author(s): 徳永万喜洋、深川暁弘、十川久美子
  • Organizer: 日本顕微鏡学会第69回学術講演会・シンポジウム“超解像顕微鏡技術と生物応用”
  • Place of Presentation: ホテル阪急エキスポパーク(大阪府)
• [Presentation] Single molecule analysis of signaling membrane proteins in T cell microcluster by multicolor live cell imaging (2013)
  • Author(s): 伊藤由馬、十川久美子、徳永万喜洋
  • Organizer: 第51回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館(京都府)
• [Presentation] FRET - based analysis of interactions between elongin B and elongin C (2013)
  • Author(s): 大山浩史、伊藤由馬、十川久美子、徳永万喜洋
  • Organizer: 第51回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館(京都府)
• [Presentation] Quantification of calcium concentration in cells by imaging analysis using GEM-GECO. (2013)
  • Author(s): 大木杜生、伊藤由馬、十川久美子、徳永万喜洋
  • Organizer: 第51回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館(京都府)
• [Presentation] Why do cells use signaling cascades with a variety of the number of steps? (2013)
  • Author(s): 深川暁弘、梶田真司、十川久美子、徳永万喜洋
  • Organizer: 第51回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館(京都府)
• [Presentation] Quantitative molecular imaging analysis of molecular dynamics of Arp4β upon transcriptional activation. (2013)
  • Author(s): 稲葉直道、伊藤由馬、原田昌彦、木村宏、徳永万喜洋、十川久美子
  • Organizer: 第51回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館(京都府)
• [Presentation] The elucidation of the mechanism of PDLIM2 localization regulation (2013)
  • Author(s): 鳥山悟、伊藤由馬、徳永万喜洋、十川久美子
  • Organizer: 第51回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館(京都府)
• [Presentation] Structural analyses for the effects of Ets1 phosphorylation on Ets1-containing TF-DNA assemblies (2013)
  • Author(s): Shiina M
  • Organizer: HUPO 2013（12th Human Proteome Organization Annual World Congress）
  • Place of Presentation: パシフィコ横浜（神奈川県）
• [Presentation] Cooperative Formation of a Multiple Transcription Factor Assembly on an Enhancer DNA and Its Regulation by Phosphorylation of a Transcription Factor via a Cell Signaling (2013)
  • Author(s): Shiina M
  • Organizer: HUPO 2013（12th Human Proteome Organization Annual World Congress）
  • Place of Presentation: パシフィコ横浜（神奈川県）
• [Presentation] DNA-mediated allosteric regulation in a complex of multiple transcription factors with DNA (2013)
  • Author(s): Shiina M
  • Organizer: 4th International Symposium on Diffraction Structural Biology
  • Place of Presentation: 名古屋市中小企業振興会館（愛知県）
• [Presentation] Crystal structural analysis of drosophila nucleosome assembly protein (2013)
  • Author(s): Hamada K
  • Organizer: 4th International Symposium on Diffraction Structural Biology
  • Place of Presentation: 名古屋市中小企業振興会館（愛知県）
• [Presentation] Allosteric Regulation of a Multiple Transcription Factor Assembly on an Enhancer DNA (2013)
  • Author(s): Shiina M
  • Organizer: 第36回日本分子生物学会
  • Place of Presentation: 神戸ポートアイランド（兵庫県）
• [Presentation] Mechanisms of DNA recognition by the Nrf2-containing transcription factor heterodimer (2013)
  • Author(s): Suzuki K
  • Organizer: 第36回日本分子生物学会
  • Place of Presentation: 神戸ポートアイランド（兵庫県）
• [Presentation] The cooperative activity of Ets1 and Runx1 on various target gene enhancers and the effect of phosphorylation of Ets1 on the cooperation (2013)
  • Author(s): Uchiyama A
  • Organizer: 第36回日本分子生物学会
  • Place of Presentation: 神戸ポートアイランド（兵庫県）
• [Presentation] Mendelian Exome Analysis (2013)
  • Author(s): Naomichi Matsumoto
  • Organizer: The 10th International Workshop on Advanced Genomics
  • Place of Presentation: National Center of Sciences（東京都）
  • Invited
• [Presentation] De novo mutations in the autophagy gene encoding WDR45 (WIPI4) cause static encephalopathy of childhood with neurodegeneration in adulthood (2013)
  • Author(s): N. Matsumoto, T. Nishimura, K. Muramatsu, H. Kodera, S. Kumada, K. Sugai, E. Kasai-Yoshida, N. Sawaura, H. Nishida, A. Hoshino, F. Ryujin, S. Yoshioka, H. Arakawa, M. Kato, N. Mizushima, H. Saitsu
  • Organizer: European Conference of Human Genetic 2013
  • Place of Presentation: Palais des Congres（フランス・パリ）
• [Presentation] 次世代シーケンサーを用いてわかってきたこと (2013)
  • Author(s): 松本直通
  • Organizer: 第17回小児分子内分泌研究会
  • Place of Presentation: 札幌北広島クラッセホテル（北海道）
  • Invited
• [Presentation] 疾患ゲノム解析における次世代シーケンサーの有用性 (2013)
  • Author(s): 松本直通
  • Organizer: 第20回日本遺伝子診療学会大会
  • Place of Presentation: アクトシティ―浜松コングレスセンター（静岡県）
  • Invited
• [Presentation] 次世代シーケンサーを用いた疾患ゲノム解析 (2013)
  • Author(s): 松本直通
  • Organizer: CiRA genomics epigenomics and bioinformatics seminar series VIII
  • Place of Presentation: CiRA京都大学（京都府）
  • Invited
• [Presentation] NGSがもたらしたヒト疾患ゲノム解析のパラダイムシフト (2013)
  • Author(s): 松本直通
  • Organizer: 現場の会第三回研究会
  • Place of Presentation: 神戸国際会議場（兵庫県）
  • Invited
• [Presentation] 次世代シーケンサーを用いた疾患ゲノム解析：現状と限界 (2013)
  • Author(s): 松本直通
  • Organizer: 第22回発達腎研究会
  • Place of Presentation: 高槻市生涯学習センター（大阪府）
  • Invited
• [Presentation] 次世代シーケンス解析で分かってきたこと (2013)
  • Author(s): 松本直通
  • Organizer: 第18回山形小児神経研究会
  • Place of Presentation: パレスグランデール（山形県）
  • Invited
• [Presentation] ヒト疾患エクソーム解析の現状と課題 (2013)
  • Author(s): 松本直通
  • Organizer: 第58回日本人類遺伝学会大会
  • Place of Presentation: 江陽グランドホテル仙台（宮城県）
  • Invited
• [Presentation] 希少疾患・難病の全エクソーム解析-現状と課題- (2013)
  • Author(s): 松本直通
  • Organizer: 日経バイオテク「希少疾患・難病の治療薬開発におけるゲノム活用」
  • Place of Presentation: 秋葉原コンベンションホ―ル（東京都）
  • Invited
• [Presentation] ATP-Dependent Stimulator of Nucleosomal Histone Acetylation (ASNA) plays a role in transcriptional regulation together with CBP/p300. (2013)
  • Author(s): Takashi Ito
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸国際会議場（兵庫県）
• [Presentation] Measuring similarity of binding modes between 3D structures of protein-small ligand complexes (2013)
  • Author(s): 笠原 浩太
  • Organizer: JCUP IV
  • Place of Presentation: 大手町サンスカイルーム（東京都）
• [Presentation] All-atomic molecular dynamics simulations of dynein motor domain in explicit water (2013)
  • Author(s): Narutoshi Kamiya, Tadaaki Mashimo, Yu Takano, Takahide Kon, Genji Kurisu, Haruki Nakamura
  • Organizer: 第13回日本蛋白質科学会年会
  • Place of Presentation: とりぎん文化会館（鳥取県）
• [Presentation] GIANT: a database for pattern analysis of protein-small ligand atomic contacts (2013)
  • Author(s): Kota Kasahara, Kengo Kinoshita
  • Organizer: 第13回日本蛋白質科学会年会
  • Place of Presentation: とりぎん文化会館（鳥取県）
• [Presentation] Prediction of Protein-Protein Interactions: Structural Approaches (2013)
  • Author(s): Haruki Nakamura
  • Organizer: The 2nd HD Physiology International Symposium
  • Place of Presentation: 丸の内MY PLAZAホール（東京都）
  • Invited
• [Presentation] The zero-dipole summation method and its application to molecular simulation with homogenous and inhomogeneous systems (2013)
  • Author(s): Ikuo Fukuda, Narutoshi Kamiya, Kota Kasahara, Haruki Nakamura
  • Organizer: The 12th Asia Pacific Physics Conference (APPC12)
  • Place of Presentation: 幕張メッセ（千葉県）
• [Presentation] GIANT: a web-server for analyzing protein-small ligand interactions based on statistically preferred patterns of atomic contacts (2013)
  • Author(s): Kota Kasahara, Kengo Kinoshita
  • Organizer: ISMB/ECCB 2013
  • Place of Presentation: ICC Berlin（ドイツ・ベルリン）
• [Presentation] All-atom molecular dynamics simulations of dynein motor domain in explicit water (2013)
  • Author(s): Narutoshi Kamiya, Tadaaki Mashimo, Yu Takano, Takahide Kon, Genji Kurisu, Haruki Nakamura
  • Organizer: Protein Society the 27th Annual Symposium
  • Place of Presentation: Boston Marriott, Copley Place（米国マサチューセッツ州）
• [Presentation] Gene Expression Changes Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) in Early Developmental Stage Embryos of Red Seabream (Pagrus major) (2013)
  • Author(s): M. Iida, Y. Murakami, Y. Shima, H. Nakamura, Y. Kagami, S. Fujii, A. Srai, H. Iwata
  • Organizer: 転写サイクル合同班会議
  • Place of Presentation: ホテルおかだ（神奈川県）
• [Presentation] ゲノム情報（1D）から蛋白質の動的構造情報（4D）へ (2013)
  • Author(s): 中村 春木
  • Organizer: 日本学術会議公開シンポジウム
  • Place of Presentation: 日本学術会議講堂（東京都）
  • Invited
• [Presentation] 分子動力学法を用いた転写因子アロステリック制御機構の検討 (2013)
  • Author(s): 笠原 浩太
  • Organizer: 計算タンパク質科学研究会
  • Place of Presentation: 鳴子観光ホテル（宮城県）
• [Presentation] Zero-dipole summation method for evaluating eletrostatic interaction in molecular simulation of biomolecular system (2013)
  • Author(s): Ikuo Fukuda, Narutoshi Kamiya, Haruki Nakamura
  • Organizer: 第51回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館（京都府）
• [Presentation] PDBnet: Integration of Structural and Biochemical Information into Protein Interaction Network (2013)
  • Author(s): Satoshi Fujii, Yuji Kawakami, Satoshi komori, Akinori Sarai
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸国際会議場（兵庫県）
• [Presentation] New approaches to dynamic properties of proteins and their applications to drug discovery of GPCR (2013)
  • Author(s): Haruki Nakamura
  • Organizer: CADD’13
  • Place of Presentation: Institut Teknologi Bandung（インドネシア・バンドン）
  • Invited
• [Presentation] TCDD曝露したマダイ胚のトランスクリプトーム解析 (2013)
  • Author(s): 飯田 緑, 藤井 聡, 内田 雅也, 中村 浩, 鏡 良弘, Bak, Su-Min, 金 恩英, 島 康洋, 岩田久人
  • Organizer: 日本内分泌撹乱化学物質学会
  • Place of Presentation: 東京大学（東京都）
• [Presentation] Computational protein science: structural bioinformatics and molecular simulations (2013)
  • Author(s): Haruki Nakamura
  • Organizer: CDAST symposium
  • Place of Presentation: Jember University（インドネシア・ジャワ）
  • Invited
• [Presentation] GAF1, a DELLA interacting protein, regulates gibberellin signaling in Arabidopsis (2013)
  • Author(s): Fukazawa J, Fujiki T, Mori M, Miyamoto C, Kamiya Y, Yamaguchi S, Takahashi Y.
  • Organizer: 21th International Plant Growth Substances Association Conference
  • Place of Presentation: 中国・上海
• [Presentation] ジベレリンによる転写制御に関与するGAF1の解析 (2013)
  • Author(s): 宮本知佳, 深澤壽太郎, 高橋陽介
  • Organizer: 第70回中国四国植物学会
  • Place of Presentation: 徳島大学（徳島県）
• [Presentation] DELLA とSCL3 によるGA 生合成酵素遺伝子の転写制御機構の解析 (2013)
  • Author(s): 寺脇綾香, 伊藤岳, 高橋陽介
  • Organizer: 第70回中国四国植物学会
  • Place of Presentation: 徳島大学（徳島県）
• [Presentation] Ca2+を介する新しいGA 信号伝達経路の探索 (2013)
  • Author(s): 岡田佳那子, 伊藤岳, 高橋陽介
  • Organizer: 第70回中国四国植物学会
  • Place of Presentation: 徳島大学（徳島県）
• [Presentation] 植物の新奇転写抑制ドメイン –真核生物に保存された転写抑制機構の解析– (2013)
  • Author(s): 伊藤岳, 岡村僚太, 高橋陽介
  • Organizer: 第36回日本分子生物学会
  • Place of Presentation: 神戸国際会議場（兵庫県）
• [Presentation] エピジェネティック制御における核内アクチン骨格の関与の解析 (2012)
  • Author(s): 山崎 祥他
  • Organizer: 第30回染色体ワークショップ・第11回核ダイナミクス研究会
  • Place of Presentation: 淡路夢舞台（兵庫）
  • Year and Date: 2012-12-19
• [Presentation] 光で観る計る生体分子のダイナミックな姿 (2012)
  • Author(s): 徳永 万喜洋
  • Organizer: 東京大学 光量子科学研究センター・レーザーアライアンス合同シンポジウム／第17回 先端光量子科学アライアンスセミナー
  • Place of Presentation: 東京大学（東京）
  • Year and Date: 2012-12-18
  • Invited
• [Presentation] ジベレリンによるDELLA-GAF1複合体を介した転写調節制御機構の解析 (2012)
  • Author(s): 深澤 壽太郎
  • Organizer: 第35回日本分子生物学会年会ワークショップ
  • Place of Presentation: 福岡国際会議場（福岡）
  • Year and Date: 2012-12-12
  • Invited
• [Presentation] 神経細胞における生体膜ラフトの動作メカニズムの解明 (2012)
  • Author(s): 戸田 収
  • Organizer: 第35回 日本分子生物学会年会
  • Place of Presentation: 福岡国際会議場（福岡）
  • Year and Date: 2012-12-12
• [Presentation] 3D-RISMを用いた酵素-DNA 複合体中の水和水分布計算 (2012)
  • Author(s): 入佐正幸
  • Organizer: 第35回溶液化学シンポジウム
  • Place of Presentation: 早稲田大学(東京）
  • Year and Date: 2012-11-12
• [Presentation] A simple non-Ewald scheme: the zero-dipole summation method and its application to molecular systems (2012)
  • Author(s): Ikuo Fukuda
  • Organizer: Conference on Computational Physics (CCP2012)
  • Place of Presentation: 神戸ポートアイランドセンター（兵庫）
  • Year and Date: 2012-10-17
• [Presentation] GAF1, A DELLA interacting protein, regulates gibberellin signaling in Arabidops (2012)
  • Author(s): Fukazawa
  • Organizer: Nature conference “Frontiers in plant biology: From discovery to applications”
  • Place of Presentation: Ghent, Belgium
  • Year and Date: 2012-10-04
• [Presentation] Molecular Dynamics Simulations of Ets1-DNA complexes using Zero-Dipole Summation Method (2012)
  • Author(s): 中村 春木
  • Organizer: 第50回日本生物物理学会年会
  • Place of Presentation: 名古屋大学(愛知）
  • Year and Date: 2012-09-24
• [Presentation] Spatial-temporal dynamics of calcium signaling and organelles in T cell activation (2012)
  • Author(s): 下沢 将啓
  • Organizer: 第50回日本生物物理学会年会
  • Place of Presentation: 名古屋大学（愛知）
  • Year and Date: 2012-09-23
• [Presentation] Single molecule analysis of T cell activation with stimulatory lipid bilayers by live cell imaging (2012)
  • Author(s): 伊藤 由馬
  • Organizer: 第50回日本生物物理学会年会
  • Place of Presentation: 名古屋大学（愛知）
  • Year and Date: 2012-09-23
• [Presentation] Quantitative analysis of changes in molecular dynamics of Arp4 upon transcriptional activation using single-molecule fluorescence imaging (2012)
  • Author(s): 一宮 勝雄
  • Organizer: 第50回日本生物物理学会年会
  • Place of Presentation: 名古屋大学（愛知）
  • Year and Date: 2012-09-23
• [Presentation] Dynamics of intracellular Ca2+ distribution measured by genetically encoded Ca2+ indicators (2012)
  • Author(s): 大山 浩史
  • Organizer: 第50回日本生物物理学会年会
  • Place of Presentation: 名古屋大学（愛知）
  • Year and Date: 2012-09-23
• [Presentation] Multifocal plane microscopy for three-dimensional molecular imaging and quantification in living cells (2012)
  • Author(s): 稲葉 直道
  • Organizer: 第50回日本生物物理学会年会
  • Place of Presentation: 名古屋大学（愛知）
  • Year and Date: 2012-09-23
• [Presentation] Quantitative analysis of single molecule imaging of physicochemical field for genetic activities (2012)
  • Author(s): 十川 久美子
  • Organizer: 第50回日本生物物理学会年会シンポジウム
  • Place of Presentation: 名古屋大学（愛知）
  • Year and Date: 2012-09-22
  • Invited
• [Presentation] The influence of solvent condition on DNA structures studied by molecular dynamics simulations (2012)
  • Author(s): Satoshi Fujii
  • Organizer: 第50回日本生物物理学会年会
  • Place of Presentation: 名古屋大学(愛知）
  • Year and Date: 2012-09-22
• [Presentation] Ion distribution in the EcoRV(restriction enzyme)-DNA complexcalculated by using 3D-RISM (2012)
  • Author(s): Masayuki Irisa
  • Organizer: Foundations of Molecular Modeling and Simulation
  • Place of Presentation: Mt. Hood, Oregon, USA
  • Year and Date: 2012-07-22
• [Presentation] Dynamics of Spatial-temporal regulation of inflammatory signaling by single molecule analysis (2012)
  • Author(s): Kumiko Sakata
  • Organizer: Gordon Research Conference Single Molecule Approaches To Biology
  • Place of Presentation: West Dover, USA
  • Year and Date: 2012-07-18
• [Presentation] Quantitative spatiotemoporal dynamics of T cell signaling using single molecule imaging (2012)
  • Author(s): Makio Tokunaga
  • Organizer: Gordon Research Conference Single Molecule Approaches To Biology
  • Place of Presentation: West Dover, USA
  • Year and Date: 2012-07-18
• [Presentation] Development of stimulatory lipid bilayer system for quantitative analysis of T cell activation by single molecule imaging (2012)
  • Author(s): Yuma Ito
  • Organizer: Gordon Research Conference Single Molecule Approaches To Biology
  • Place of Presentation: West Dover, USA
  • Year and Date: 2012-07-18
• [Book] 遺伝子発現制御機構 クロマチン，転写制御，エピジェネティクス (2017)
  • Author(s): 田村隆明、浦清恵、山口雄輝ほか
  • Total Pages: 264
  • Publisher: 東京化学同人
• [Book] 植物生理学概論第二版 (2017)
  • Author(s): 桜井英博、柴岡弘郎、高橋陽介、小関良宏、藤田知道
  • Publisher: 培風館
• [Book] 生命のメカニズム - 美しいイメージで学ぶ構造生命科学入門 (2015)
  • Author(s): 中村春木（監訳）、工藤高裕、西川建、中村春木（訳）
  • Total Pages: 168
  • Publisher: シナジー
• [Book] １分子生物学 (2014)
  • Author(s): 原田 慶恵、石渡 信一、宝谷 紘一、船津 高志、城口 克之、吉田 賢右、上村 想太郎、井出 徹、佐甲 靖志、上田 昌宏、十川 久美子、樋口 秀男、多田隈 尚史、渡邉 朋信、徳永 万喜洋、石島 秋彦、安藤 敏夫、岡田 康志、他
  • Total Pages: 7
  • Publisher: 化学同人
• [Book] 見てわかる構造生命科学 - 生命科学研究へのタンパク質構造の利用 - (2014)
  • Author(s): 椎名政昭，緒方一博
  • Total Pages: 28
  • Publisher: 化学同人
• [Book] 見てわかる構造生命科学 - 生命科学研究へのタンパク質構造の利用 - (2014)
  • Author(s): 中村春木（編）、中村春木他9名
  • Total Pages: 326
  • Publisher: 化学同人
• [Book] 生命科学から創薬へのイノベーション (2014)
  • Author(s): 米田悦啓、堤康央、石井健（編）、中村春木他45名
  • Total Pages: 202
  • Publisher: 南山堂
• [Book] 基礎からしっかり学ぶ生化学 (2014)
  • Author(s): 山口雄輝、成田央
  • Total Pages: 245
  • Publisher: 羊土社
• [Book] Fundamentals of Chromatin (Chapter 8 Histone Phosphorylation and Chromatin Dynamics) (2014)
  • Author(s): Mizusaki H, Aihara H, Ito T.
  • Total Pages: 587
  • Publisher: Springer Science+Business Media New York
• [Book] Biomolecular Forms and Functions (2013)
  • Author(s): Eiji Kanamori
  • Total Pages: 502
  • Publisher: World Scientific Publishing
• [Remarks] 新学術領域研究「転写サイクル」ウェブサイト
  • URL: http://transcriptioncycle.org
• [Remarks] 新学術領域研究「転写サイクル」
  • URL: http://transcriptioncycle.org/
• [Remarks] 新学術領域「転写サイクル」
  • URL: http://transcriptioncycle.org
• [Remarks] 新学術領域「転写サイクル」
  • URL: http://transcriptioncycle.org
• [Patent(Industrial Property Rights)] 重度の知的障害及び運動発達遅滞を伴う難治性てんかんの検出方法 (2014)
  • Inventor(s): 松本直通・才津浩智
  • Industrial Property Rights Holder: 横浜市立大学
  • Industrial Property Rights Type: 特許
  • Filing Date: 2014-06-09
  • Overseas
• [Patent(Industrial Property Rights)] コフィン－シリス症候群の検出方法 (2014)
  • Inventor(s): 松本直通・三宅紀子・鶴崎美徳
  • Industrial Property Rights Holder: 横浜市立大学
  • Industrial Property Rights Type: 特許
  • Filing Date: 2014-07-14
• [Patent(Industrial Property Rights)] 孔脳症又は脳出血のリスクを予測する方法 (2014)
  • Inventor(s): 松本直通・才津浩智
  • Industrial Property Rights Holder: 横浜市立大学
  • Industrial Property Rights Type: 特許
  • Filing Date: 2014-05-09
  • Overseas
• [Patent(Industrial Property Rights)] Coffin-Siris症候群の新規遺伝子診断法 (2013)
  • Inventor(s): 鶴崎美徳、松本直通
  • Industrial Property Rights Holder: 鶴崎美徳、松本直通
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2013-252720
  • Filing Date: 2013-12-06