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Cell competition: a mechanism for survival of the fittest in the multi-cellular community

Administrative Group

Project AreaCell competition: a mechanism for survival of the fittest in the multi-cellular community
Project/Area Number 26114001
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionHokkaido University

Principal Investigator

Fujita Yasuyuki  北海道大学, 遺伝子病制御研究所, 教授 (50580974)

Co-Investigator(Kenkyū-buntansha) 一條 秀憲  東京大学, 大学院薬学系研究科(薬学部), 教授 (00242206)
井垣 達吏  京都大学, 生命科学研究科, 教授 (00467648)
鈴木 聡  神戸大学, 医学研究科, 教授 (10311565)
石谷 太  九州大学, 生体防御医学研究所, 共同研究員 (40448428)
高井 義美  神戸大学, 医学研究科, 特命教授 (60093514)
倉永 英里奈  東北大学, 生命科学研究科, 教授 (90376591)
Project Period (FY) 2014-07-10 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥48,750,000 (Direct Cost: ¥37,500,000、Indirect Cost: ¥11,250,000)
Fiscal Year 2018: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2017: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2016: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2015: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2014: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Keywords細胞競合
Outline of Final Research Achievements

We organized 1st, 2nd, 3rd Cell Competition International Symposium in 2015 (Kyoto), 2016 (Madrid) and 2017 (Sapporo), respectively. Also we held general meeting for this reseach area, and 'Cell Competition colloquium’ to boost education for young scientists. In addition, to facilitate research collaboration between young scientists, we set up specific research funding and support 6 pairs of intra-area collaborations. Furtheremore, by technical support center organized by 6 main researchers, we support the research and collborative studies within the area.

Academic Significance and Societal Importance of the Research Achievements

本領域では、世界的にも類を見ない細胞競合の統合的融合研究拠点を構築し、多角的かつ包括的に細胞競合研究を強力に推進する。それによって、細胞競合を制御する分子メカニズムの全貌を解明し、それらがどのように多細胞生命体の個体発生や恒常性維持に関わっているのか、またその破綻がどのような疾患や病態を引き起こすのかを明らかにする。
本研究総括班は、上記融合研究の活動を円滑に推進するために、研究の効率化と研究グループ間の有機的な結合を積極的に支援・調整する役割を担った。

Report

(6 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (72 results)

All 2018 2017 2016 2015 2014 Other

All Int'l Joint Research (10 results) Journal Article (22 results) (of which Int'l Joint Research: 9 results,  Peer Reviewed: 22 results,  Open Access: 18 results,  Acknowledgement Compliant: 4 results) Presentation (35 results) (of which Int'l Joint Research: 29 results,  Invited: 34 results) Remarks (2 results) Patent(Industrial Property Rights) (1 results) Funded Workshop (2 results)

  • [Int'l Joint Research] University College London/Imperial College/Oxford University(英国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of San Francisco/Marine Biological Laboratory(MBL)(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] EPFL(スイス)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University College London/Imperial Colledge London(英国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Swiss Institute of Technology Lausanne(スイス)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Stowers Institute for Medical Research(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University College London/University of Cardiff/University of Exeter(英国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] dkfz/Hubrecht Institute(ドイツ)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] University of Bern/ETH Zurich(スイス)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] University of Tronto/Cambell Family Institute(カナダ)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues2018

    • Author(s)
      Sasaki Ayana、Nagatake Takahiro、Egami Riku、Gu Guoqiang、Takigawa Ichigaku、Ikeda Wataru、Nakatani Tomoya、Kunisawa Jun、Fujita Yasuyuki
    • Journal Title

      Cell Reports

      Volume: 23 Issue: 4 Pages: 974-982

    • DOI

      10.1016/j.celrep.2018.03.104

    • NAID

      120006489805

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells2018

    • Author(s)
      Watanabe Hirotaka、Ishibashi Kojiro、Mano Hiroki、Kitamoto Sho、Sato Nanami、Hoshiba Kazuya、Kato Mugihiko、Matsuzawa Fumihiko、Takeuchi Yasuto、Shirai Takanobu、Ishikawa Susumu、Morioka Yuka、Imagawa Toshiaki、Sakaguchi Kazuyasu、Yonezawa Suguru、Kon Shunsuke、Fujita Yasuyuki
    • Journal Title

      Cell Reports

      Volume: 23 Issue: 13 Pages: 3721-3729

    • DOI

      10.1016/j.celrep.2018.05.081

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells2018

    • Author(s)
      Yako Yuta、Hayashi Takashi、Takeuchi Yasuto、Ishibashi Kojiro、Kasai Nobuhiro、Sato Nanami、Kuromiya Keisuke、Ishikawa Susumu、Fujita Yasuyuki
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 9639-9639

    • DOI

      10.1038/s41598-018-27469-z

    • NAID

      120006502509

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Accumulation of the myosin-II-spectrin complex plays a positive role in apical extrusion of Src-transformed epithelial cells2018

    • Author(s)
      Mikio Takagi, Masaya Ikegawa, Takashi Shimada, Susumu Ishikawa, Mihoko Kajita, Takeshi Maruyama, Tomoko Kamasaki, Yasuyuki Fujita
    • Journal Title

      Genes to Cells

      Volume: 23 (11) Issue: 11 Pages: 974-981

    • DOI

      10.1111/gtc.12643

    • NAID

      120006734160

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation2018

    • Author(s)
      Kasai Nobuhiro、Kadeer Ailijiang、Kajita Mihoko、Saitoh Sayaka、Ishikawa Susumu、Maruyama Takeshi、Fujita Yasuyuki
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 2097-2097

    • DOI

      10.1038/s41598-018-20146-1

    • NAID

      120006456414

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cell Extrusion: A Stress-Responsive Force for Good or Evil in Epithelial Homeostasis2018

    • Author(s)
      Ohsawa Shizue、Vaughen John、Igaki Tatsushi
    • Journal Title

      Developmental Cell

      Volume: 44 Issue: 3 Pages: 284-296

    • DOI

      10.1016/j.devcel.2018.01.009

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cell competition in mammals; novel homeostatic machinery for embryonic development and cancer prevention2017

    • Author(s)
      Maruyama Takeshi、Fujita Yasuyuki
    • Journal Title

      Current Opinion in Cell Biology

      Volume: 48 Pages: 106-112

    • DOI

      10.1016/j.ceb.2017.06.007

    • NAID

      120006523718

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes.2017

    • Author(s)
      Shunsuke Kon, et al.
    • Journal Title

      Nature Cell Biology

      Volume: 印刷中 Issue: 5 Pages: 530-541

    • DOI

      10.1038/ncb3509

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] YAP determines the cell fate of injured mouse hepatocytes in vivo2017

    • Author(s)
      Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H.
    • Journal Title

      Nat Commun

      Volume: 8 Issue: 1 Pages: 16017-16017

    • DOI

      10.1038/ncomms16017

    • NAID

      120006373756

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nectin-like molecule-4/cell adhesion molecule 4 inhibits the ligand-induced dimerization of ErbB3 with ErbB22017

    • Author(s)
      Mizutani Kiyohito、Kedashiro Shin、Maruoka Masahiro、Ueda Yuki、Takai Yoshimi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 11375-11375

    • DOI

      10.1038/s41598-017-10107-5

    • NAID

      120006373795

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Planar polarized contractile actomyosin networks in dynamic tissue morphogenesis2017

    • Author(s)
      Umetsu Daiki、Kuranaga Erina
    • Journal Title

      Current Opinion in Genetics & Development

      Volume: 45 Pages: 90-96

    • DOI

      10.1016/j.gde.2017.03.012

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Plectin is a novel regulator for apical extrusion of RasV12-transformed cells.2017

    • Author(s)
      Kadeer, A., Maruyama, T., Kajita, M., Morita T., Sasaki, A., Ohoka, A., Ishikawa, S., Ikegawa, M., Shimada, T., and Fujita, Y.
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 44328-44328

    • NAID

      120006219881

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells.2017

    • Author(s)
      S. Saitoh, T. Maruyama, Y. Yako, M. Kajita, Y. Fujioka, Y. Ohba, N. Kasai, N. Sugama, S. Kon, S. Ishikawa, T. Hayashi, T. Yamazaki, M. Tada and Y. Fujita.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A.

      Volume: 114 Issue: 12

    • DOI

      10.1073/pnas.1602349114

    • NAID

      120006346108

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status.2016

    • Author(s)
      Chiba, T., Ishihara, E., Miyamura, N., Narumi, R., Kajita, M., Fujita, Y., Suzuki, A., Ogawa, Y. and *Nishina, H.
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 28383-28383

    • DOI

      10.1038/srep28383

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] EphA2 Drives the Segregation of Ras-Transformed Epithelial Cells from Normal Neighbors.2016

    • Author(s)
      Porazinski,S., Navascues, J., Yako, Y., Hill, W., Jones, M.R., Maddison, R., Fujita, Y., and Hogan, C.
    • Journal Title

      Current Biology

      Volume: 5 Issue: 23 Pages: 3220-3229

    • DOI

      10.1016/j.cub.2016.09.037

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] A role of the sphingosine-1-phosphate (S1P)- S1P receptor 2 pathway in Epithelial Defense Against Cancer (EDAC)2015

    • Author(s)
      Yamamoto, S., Yako, Y., Fujioka, Y., Kajita, M., Kameyama, T., Kon, S., Ishikawa, S., Ohba, Y., Ohno, Y., Kihara, A., and Fujita, Y.
    • Journal Title

      Molecular Biology of the Cell

      Volume: 27(3) Issue: 3 Pages: 491-499

    • DOI

      10.1091/mbc.e15-03-0161

    • NAID

      120005740332

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia.2015

    • Author(s)
      Yamauchi, H., Matsumaru, T., Morita, T., Ishikawa, S., Maenaka, K., Takigawa, I., Semba, K., Kon, S. and Fujita, Y.
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 15336-15336

    • DOI

      10.1038/srep15336

    • NAID

      120005674073

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] EDAC: Epithelial defence against cancer- cell competition between normal and transformed epithelial cells in mammals.2015

    • Author(s)
      Kajita, M. and Fujita, Y.
    • Journal Title

      Journal of Biochemistry

      Volume: 158(1) Issue: 1 Pages: 15-23

    • DOI

      10.1093/jb/mvv050

    • NAID

      40020522502

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] EPLIN is a crucial regulator for extrusion of RasV12-transformed cells.2015

    • Author(s)
      Ohoka, A., Kajita, M., Ikenouchi, J., Yako, Y., Kitamoto, S., Kon, S., Ikegawa, M., Shimada, T., Ishikawa, S., and Fujita, Y.
    • Journal Title

      Journal of Cell Science

      Volume: 128 Pages: 781-789

    • DOI

      10.1242/jcs.163113

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Filamin acts as a key regulator in epithelial defence against transformed cells.2014

    • Author(s)
      Kajita, M., Sugimura, K., Ohoka, A., Burden, J., Suganuma, H., Ikegawa, M., Shimada, T., Kitamura, T., Shindoh, M., Ishikawa, S., Yamamoto, S., Saitoh, S., Yako, Y., Takahashi, R., Okajima, T., Kikuta, J., Maijima, Y., Ishii, M., Tada, M., and Fujita, Y.
    • Journal Title

      Nature Communications

      Volume: 5:4428

    • NAID

      120005537465

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium.2014

    • Author(s)
      Anton, K. A., Sinclair, J., Ohoka, A., Kajita, M., Ishikawa, S., Benz, P. M., Renne, T., Balda, M., Jorgensen, C., Matter, K., and Fujita, Y.
    • Journal Title

      Journal of Cell Science

      Volume: 127 Pages: 3425-3433

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic and influential interaction of cancer cells with normal epithelial cells in 3D culture.2014

    • Author(s)
      Ivers LP, Cummings B, Owolabi F, Welzel K, Klinger R, Saitoh S, O'Connor D, Fujita Y, Scholz D, Itasaki N.
    • Journal Title

      Cancer Cell International

      Volume: Volume 14 Issue: 1

    • DOI

      10.1186/s12935-014-0108-6

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] Calcium wave triggers cell extrusion2018

    • Author(s)
      Yasuyuki Fujita
    • Organizer
      Gordon Research Conferences, Cell Polarity Signaling
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 細胞間コミュニケーションの究極の理解を目指して~Cell Competition and Beyond2018

    • Author(s)
      藤田 恭之
    • Organizer
      第91回日本生化学会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 正常上皮細胞と変異細胞に生じる細胞競合2018

    • Author(s)
      藤田 恭之
    • Organizer
      第77回日本癌学会学術総会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Sequential Oncogene Mutations Profoundly Influence the Outcome of Cell Competition2018

    • Author(s)
      Yasuyuki Fujita
    • Organizer
      Cell Competition in Development and Disease
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 正常上皮細胞と変異細胞に生じる細胞競合2018

    • Author(s)
      藤田 恭之
    • Organizer
      第18回日本再生医療学会総会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Mechanisms and roles of tumor-suppressive cell competition2018

    • Author(s)
      井垣達吏
    • Organizer
      Cell Competition in Development and Cancer” 2018
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 正常上皮細胞と変異細胞間に生じる細胞競合2017

    • Author(s)
      藤田 恭之
    • Organizer
      第16回日本再生医療学会総会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-07
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell competition between normal and transformed epithelial cells2017

    • Author(s)
      藤田 恭之
    • Organizer
      The 15th Stem Cell Research Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 細胞競合を利用した新規がん予防的治療薬の開発2017

    • Author(s)
      藤田 恭之
    • Organizer
      日本ケミカルバイオロジー学会第12回年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Cell competition between Normal and Transformed Epithelial Cells2017

    • Author(s)
      藤田 恭之
    • Organizer
      24th Asia Pacific Cancer Conference (APCC2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 細胞競合とWarburg effect2017

    • Author(s)
      藤田 恭之
    • Organizer
      第6回がんと代謝研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 細胞競合とワールブルグ効果2017

    • Author(s)
      藤田 恭之
    • Organizer
      第42回 日本医用マススペクトル学会年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Cell competition: Cancer-host network in carcinogenesis 細胞競合:発がんにおけるがんー宿主ネットワーク2017

    • Author(s)
      藤田 恭之
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell competition between normal and transformed epithelial cells in mammals2017

    • Author(s)
      藤田 恭之
    • Organizer
      CHAMPALIMAUD RESEARCH SYMPOSIUM 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell Cimpetition between normal and trandformed epithelial cells2017

    • Author(s)
      藤田 恭之
    • Organizer
      12th International Symposium of the Institute Network
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 細胞競合の分子機構と生理的意義:どこまでわかって何がわからないのか2017

    • Author(s)
      藤田 恭之
    • Organizer
      2017年度 生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Collective cell movement during epithelial morphogenesis2017

    • Author(s)
      倉永英里奈
    • Organizer
      Asia-Pacific Drosophila Research Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Mechanical perspective of collective cell movement in looping morphogenesis2017

    • Author(s)
      倉永英里奈
    • Organizer
      EMBO workshop"Dynamics of living systems”
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell competition and Warburg effect2016

    • Author(s)
      藤田 恭之
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell competition and Warburg effect2016

    • Author(s)
      藤田 恭之
    • Organizer
      Cell Competition, Apoptosis and Cancer
    • Place of Presentation
      Fundacion Ramon Areces, Spain
    • Year and Date
      2016-10-25
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 細胞競合がもたらすワーブルグ効果様の代謝変化2016

    • Author(s)
      藤田 恭之
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] EDAC(Epitherial Defence Against Cancer)2016

    • Author(s)
      藤田 恭之
    • Organizer
      第25回日本Cell Death 学会学術集会
    • Place of Presentation
      きゅりあん(品川区立総合区民会館)(東京都品川区)
    • Year and Date
      2016-09-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell competition in mammalian carcinogenesis2016

    • Author(s)
      藤田 恭之
    • Organizer
      CELL COMPETITION IN FLIES AND MICE in The Allied Genetics Conference 2016
    • Place of Presentation
      Orlando World Center Marriott, USA
    • Year and Date
      2016-07-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Competitve interactions between normal and transformed epithelial cells2015

    • Author(s)
      藤田 恭之
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸国際会議場(神戸市、兵庫県)
    • Year and Date
      2015-12-01
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] EDAC(Epitherial Defence Against Cancer)2015

    • Author(s)
      藤田 恭之
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋市、愛知県)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell Competition and Warburg effect2015

    • Author(s)
      藤田 恭之
    • Organizer
      第1回国際シンポジウム Cell Competition in Development and Cancer
    • Place of Presentation
      京都大学(京都市、京都府)
    • Year and Date
      2015-09-10
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] EDAC(Epitherial Defence Against Cancer)2015

    • Author(s)
      藤田 恭之
    • Organizer
      第33回日本ヒト細胞学会学術集会
    • Place of Presentation
      ホテルスカイタワー(宮崎市、宮崎県)
    • Year and Date
      2015-08-22
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 細胞競合とWarburg effect2015

    • Author(s)
      藤田 恭之
    • Organizer
      第3回がんと代謝研究会
    • Place of Presentation
      石川県立音楽堂(金沢市、石川県)
    • Year and Date
      2015-07-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] EDAC(Epitherial Defence Against Cancer)2015

    • Author(s)
      藤田 恭之
    • Organizer
      第67回日本細胞生物学会
    • Place of Presentation
      タワーホール船堀(江戸川区、東京都)
    • Year and Date
      2015-06-29
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cell to Cell competition: survival of the fittest as a system of a cellular society2015

    • Author(s)
      藤田 恭之
    • Organizer
      RISK-IR MEETING「Integration and Conceptual Framework Meeting」
    • Place of Presentation
      BIOPARK(パリ、フランス)
    • Year and Date
      2015-04-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] EDAC:Epithelial Defense Against Cancer2014

    • Author(s)
      藤田 恭之
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-11-25
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] EDAC:Epithelial Defense Against Cancer2014

    • Author(s)
      藤田 恭之
    • Organizer
      Cold Spring Harbor Conference Asia
    • Place of Presentation
      蘇州市、中国
    • Year and Date
      2014-11-17
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Interface between normal and transformed epithlial cells2014

    • Author(s)
      藤田 恭之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      グランドプリンスホテル京都(京都市)
    • Year and Date
      2014-10-15
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 正常上皮細胞と変異細胞の相互作用-新規がん治療法の確立を目指して-2014

    • Author(s)
      藤田 恭之
    • Organizer
      第33回 分子病理学研究会~宮城蔵王シンポジウム~
    • Place of Presentation
      宮城蔵王ロイヤルホテル(宮城県刈田郡蔵王町)
    • Year and Date
      2014-07-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Interface between normal and transformed epithlial cells - A road to a novel type of cancer treatment -2014

    • Author(s)
      藤田 恭之
    • Organizer
      国際シンポジウム COMMON MOLECULAR BASIS OF CANCER AND NEURODEGENERATIVE DISEASES, TWO MAJOR HURDLES TO OVERCOME FOR GOOD QUALITY OF LONGEVITY
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-06-27
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Remarks] 北海道大学 遺伝子病制御研究所 分子腫瘍分野

    • URL

      http://www.igm.hokudai.ac.jp/oncology/index.html

    • Related Report
      2018 Annual Research Report
  • [Remarks] 北海道大学 遺伝子病制御研究所 分子腫瘍分野のホームページ

    • URL

      http://www.igm.hokudai.ac.jp/oncology/index.html

    • Related Report
      2015 Annual Research Report
  • [Patent(Industrial Property Rights)] トランスジェニック非ヒト哺乳動物及び該動物を用いたがん治療薬のスクリーニング方法2016

    • Inventor(s)
      藤田 恭之
    • Industrial Property Rights Holder
      藤田 恭之
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-054719
    • Filing Date
      2016-03-18
    • Related Report
      2015 Annual Research Report
  • [Funded Workshop] 3rd International symposium on cell competition2017

    • Related Report
      2017 Annual Research Report
  • [Funded Workshop] 第1回国際シンポジウム Cell Competition in Development and Cancer2015

    • Place of Presentation
      京都大学(京都市、京都府)
    • Year and Date
      2015-09-10
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2014-11-20   Modified: 2022-03-29  

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