Molecular Transformation by Metal catalyst with new Ligand changing Volume

• Project Area: Precise Formation of a Catalyst Having a Specified Field for Use in Extremely Difficult Substrate Conversion Reactions
• Project/Area Number: 15H05803
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Osaka University
• Principal Investigator: Ogoshi Sensuke 大阪大学, 工学研究科, 教授 (30252589)
• Project Period (FY): 2015-06-29 – 2020-03-31
• Project Status: Completed (Fiscal Year 2020)
• Budget Amount: ¥43,160,000 (Direct Cost: ¥33,200,000、Indirect Cost: ¥9,960,000); Fiscal Year 2019: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2018: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2017: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2016: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2015: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
• Keywords: 触媒 / 分子変換 / 地球温暖化ガス対策 / 触媒的結合形成反応 / 二酸化炭素の有効利用 / 典型元素 / 合成化学 / 触媒化学 / 有機金属化学 / N-ヘテロサイクリックカルベン / 二酸化炭素 / 混合酸無水物 / Ｎ-ヘテロサイクリックカルベン / フラストレイトルイスペア / 小分子活性化 / 外部刺激応答

Outline of Final Research Achievements

Direct synthesis of carboxylic-phosphinic mixed anhydrides has been achieved by treating carbon dioxide with
Recently,wereported the synthesis ofN-phosphine oxideN-phosphine oxide-substituted imidazolylidenes (PoxIms) that contain both nucleophilic carbene and electrophilic phosphorus moieties.This novel mixed anhydride was efficiently derivatized into an ester,anamide,and an unsymmetrical ketone via transformation into its corresponding imidazolium salt followed by adual substitution reaction. The presented work used well-designed multifunctional carbene reagents to establish anovel utility for carbon dioxide in organic synthesis.

Academic Significance and Societal Importance of the Research Achievements

地球温暖化は確実に進行しており、ここ数年の気候変動はその端緒に過ぎないと考えられる。この様な背景のもと我々科学者は地球温暖化ガスの削減に対して積極的に関与する事がもとめられている。本研究においては二酸化炭素の有効利用利用だけに留まる温暖化温暖化能が二酸化炭素の１万５千倍のフルオロホルムの有効利用にも役立つ新触媒の開発にもとりくんでいまｓ。

Research Products

• [Int'l Joint Research] University of Barcelona(スペイン)
• [Int'l Joint Research] Laboratoire de Chimie de Coordination(フランス)
• [Journal Article] Development of Metal Complexes Equipped with Structurally Flexible Carbenes (2021)
  • Author(s): Yoichi Hoshimoto * and Sensuke Ogoshi *
  • Journal Title: Bulletin of the Chemical Society of Japan Volume: 94 Issue: 1 Pages: 323-338
  • DOI: 10.1246/bcsj.20200293
  • NAID: 130007968755
  • Peer Reviewed / Open Access
• [Journal Article] Direct Transformation of Tetrafluoroethylene to Trifluorovinylzinc via sp(2) C-F Bond Activation (2020)
  • Author(s): Kikushima, K. Etou, Y. Kamura, R. Takeda, I. Ito, H. Ohashi, M. Ogoshi, S.
  • Journal Title: Organic Letters Volume: 22 Issue: 20 Pages: 8167-8172
  • DOI: 10.1021/acs.orglett.0c03189
  • Peer Reviewed
• [Journal Article] Enantioselective Synthesis of Polycyclic gamma-Lactams with Multiple Chiral Carbon Centers via Ni(0)-Catalyzed Asymmetric Carbonylative Cycloadditions without Stirring (2020)
  • Author(s): Ashida, K. Hoshimoto, Y. Tohnai, N. Scott, D. E. Ohashi, M. Imaizumi, H. Tsuchiya, Y. Ogoshi, S.
  • Journal Title: Journal of the American Chemical Society Volume: 142 Issue: 45 Pages: 1594-1602
  • DOI: 10.1021/jacs.0c09639
  • Peer Reviewed
• [Journal Article] Rotation-Triggered Transmetalation on a Heterobimetallic Cu/Al N-Phosphine-Oxide-Substituted Imidazolylidene Complex (2020)
  • Author(s): Asada, T. Hoshimoto, Y. Ogoshi, S.
  • Journal Title: Journal of the American Chemical Society Volume: 142 Issue: 21 Pages: 9772-9784
  • DOI: 10.1021/jacs.0c03252
  • Peer Reviewed / Open Access
• [Journal Article] Complexation between MOTf (M = Li and Na) and N-Phosphine Oxide-substituted Imidazolylidenes via Coordination of the N-Phosphoryl Groups (2019)
  • Author(s): Kinoshita Takuya、Sakuraba Mahiro、Hoshimoto Yoichi、Ogoshi Sensuke
  • Journal Title: Chemistry Letters Volume: 48 Issue: 3 Pages: 230-233
  • DOI: 10.1246/cl.180930
  • NAID: 130007607701
  • Peer Reviewed / Open Access
• [Journal Article] Main-Group-Catalyzed Reductive Alkylation of Multiply Substituted Amines with Aldehydes Using H2 (2018)
  • Author(s): Hoshimoto Yoichi、Kinoshita Takuya、Hazra Sunit、Ohashi Masato、Ogoshi Sensuke
  • Journal Title: Journal of the American Chemical Society Volume: 140 Issue: 23 Pages: 7292-7300
  • DOI: 10.1021/jacs.8b03626
  • Peer Reviewed
• [Journal Article] Highly Atom Economical Molecular Transformation via Hetero-Nickelacycle (2017)
  • Author(s): Ogoshi Sensuke
  • Journal Title: Bulletin of the Chemical Society of Japan Volume: 90 Issue: 12 Pages: 1401-1406
  • DOI: 10.1246/bcsj.20170268
  • NAID: 130006250396
  • ISSN: 0009-2673, 1348-0634
  • Peer Reviewed / Open Access
• [Journal Article] N-Phosphine Oxide-Substituted Imidazolylidenes (PoxIms): Multifunctional Multipurpose Carbenes (2017)
  • Author(s): Hazra Sunit、Hoshimoto Yoichi、Ogoshi Sensuke
  • Journal Title: Chemistry - A European Journal Volume: 23 Issue: 61 Pages: 15238-15243
  • DOI: 10.1002/chem.201703644
  • Peer Reviewed / Open Access
• [Journal Article] Phosphorylation of Isocyanates and Aldehydes Mediated by Multifunctional <i>N</i>-Phosphine Oxide-substituted Imidazolylidenes (2017)
  • Author(s): Hoshimoto Yoichi、Asada Takahiro、Hazra Sunit、Ohashi Masato、Ogoshi Sensuke
  • Journal Title: Chemistry Letters Volume: 46 Issue: 8 Pages: 1211-1213
  • DOI: 10.1246/cl.170475
  • NAID: 130005906964
  • ISSN: 0366-7022, 1348-0715
  • Peer Reviewed / Open Access
• [Journal Article] Nickel(0)-catalyzed Coupling Reactions of Carbonyls and Alkenes with Reducing Reagents Giving Six- and Seven-membered Benzocycloalkanols (2017)
  • Author(s): Hayashi Yukari、Hoshimoto Yoichi、Kumar Ravindra、Ohashi Masato、Ogoshi Sensuke
  • Journal Title: Chemistry Letters Volume: 46 Issue: 8 Pages: 1096-1098
  • DOI: 10.1246/cl.170394
  • NAID: 130005906982
  • Peer Reviewed / Open Access
• [Journal Article] Two-step synthesis of chiral fused tricyclic scaffolds from phenols via desymmetrization on nickel (2017)
  • Author(s): Kumar Ravindra、Hoshimoto Yoichi、Tamai Eri、Ohashi Masato、Ogoshi Sensuke
  • Journal Title: Nature Communications Volume: 8 Issue: 1 Pages: 32-38
  • DOI: 10.1038/s41467-017-00068-8
  • Peer Reviewed / Open Access
• [Journal Article] Efficient Synthesis of Polycyclic γ-Lactams by Catalytic Carbonylation of Ene-Imines via Nickelacycle Intermediates (2017)
  • Author(s): Hoshimoto Yoichi、Ashida Keita、Sasaoka Yukari、Kumar Ravindra、Kamikawa Ken、Verdaguer Xavier、Riera Antoni、Ohashi Masato、Ogoshi Sensuke
  • Journal Title: Angewandte Chemie International Edition Volume: 56 Issue: 28 Pages: 8206-8210
  • DOI: 10.1002/anie.201703187
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Copolymerisation of ethylene with polar monomers by using palladium catalysts bearing an N-heterocyclic carbene-phosphine oxide bidentate ligand (2017)
  • Author(s): Tao, W.; Akita, S.; Nakano, R.; Ito, S.; Hoshimoto, Y.; Ogoshi, S.; Nozaki, K.
  • Journal Title: Chemical Communications Volume: 53 Issue: 17 Pages: 2630-2633
  • DOI: 10.1039/c7cc00002b
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Kinetic and Theoretical Studies on Ni(0)/N-Heterocyclic Carbene-Catalyzed Intramolecular Alkene Hydroacylation (2017)
  • Author(s): Y. Hoshimoto, Y. Hayashi, M. Ohashi, S. Ogoshi
  • Journal Title: Chem. Asian J. Volume: 12 Issue: 3 Pages: 278-282
  • DOI: 10.1002/asia.201601313
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Strategic Utilization of Multifunctional Carbene for Direct Synthesis of Carboxylic-Phosphinic Mixed Anhydride from CO2 (2016)
  • Author(s): Y. Hoshimoto, T. Asada, S. Hazra, T. Kinoshita, P. Sombut, R. Kumar, M. Ohashi, S. Ogoshi
  • Journal Title: Angew. Chem. Int. Ed. Volume: 55 Issue: 52 Pages: 16075-16079
  • DOI: 10.1002/anie.201609710
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Nickel(0)-Catalyzed Intramolecular Reductive Coupling of Alkenes and Aldehydes or Ketones with Hydrosilanes (2016)
  • Author(s): Yukari Hayashi, Yoichi Hoshimoto, Ravindra Kumar, Masato Ohashi, Sensuke Ogoshi
  • Journal Title: Chemical Communications Volume: 未定 Issue: 37 Pages: 6237-6240
  • DOI: 10.1039/c6cc01915c
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Nickel(0)/N-Heterocyclic Carbene-Catalyzed Asymmetric [2+2+2] Cycloaddition of Two Enones and an Alkyne: Access to Cyclohexenes with Four Contiguous Stereogenic Centers (2015)
  • Author(s): R. Kumar, H. Tokura, A. Nishimura, T. Mori, Y. Hoshimoto, M. Ohashi, S. Ogoshi
  • Journal Title: Org. Lett. Volume: 17 Issue: 24 Pages: 6018-6021
  • DOI: 10.1021/acs.orglett.5b02983
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Copper-Catalyzed Reaction of Trifluoromethylketones with Aldehydes via a Copper Difluoroenolate (2015)
  • Author(s): Doi, R.; Ohashi, M.; Ogoshi, S.
  • Journal Title: Angewandte Chemie International Edition Volume: 55 Issue: 1 Pages: 341-344
  • DOI: 10.1002/anie.201508266
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Nickel(0)-Catalyzed Enantio- and Diastereoselective Synthesis of Benzoxasiloles: Ligand-Controlled Switching from Inter- to Intramolecular Aryl-Transfer Process (2015)
  • Author(s): Kumar, R.; Hoshimoto, Y.; Yabuki, H.; Ohashi, M.; Ogoshi, S.
  • Journal Title: Journal of the American Chemical Society Volume: 137 Issue: 36 Pages: 11838-11845
  • DOI: 10.1021/jacs.5b07827
  • Peer Reviewed
• [Journal Article] A Strategy to Control the Reactivationl of Frustrated Lewis Pairs from Shelf-Stable Carbene-Borane Complexes (2015)
  • Author(s): Yoichi Hoshimoto, Takuya Kinoshita, Masato Ohashi, Sesuke Ogoshi
  • Journal Title: Angew. Chem. Int. Ed. Volume: 54 Issue: 40 Pages: 11666-11671
  • DOI: 10.1002/anie.201505974
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Catalytic Transformation of Aldehydes with Nickel Complexes through η2 Coordination and Oxidative Cyclization (2015)
  • Author(s): Hoshimoto, Y.; Ohashi, M.; Ogoshi, S
  • Journal Title: Accounts of Chemical Research Volume: 48 Issue: 6 Pages: 1746-1755
  • DOI: 10.1021/acs.accounts.5b00061
  • Peer Reviewed
• [Journal Article] Nickel-Catalyzed Formation of Fluorine-Containing Ketones via the Selective Cross-Trimerization Reaction of Tetrafluoroethylene, Ethylene, and Aldehydes (2015)
  • Author(s): Ohashi, M.; Shirataki, H.; Kikushima, K.; Ogoshi, S.
  • Journal Title: Journal of the American Chemical Society Volume: 137 Issue: 20 Pages: 6496-6499
  • DOI: 10.1021/jacs.5b03587
  • Peer Reviewed
• [Journal Article] Copper-mediated One-pot Synthesis of Trifluorostyrene Derivatives from Tetrafluoroethylene and Arylboronate (2015)
  • Author(s): Kikushima, K.; Sakaguchi, H.; Saijo, H.; Ohashi, M.; Ogoshi, S.
  • Journal Title: Chemistry Letters Volume: 44 Issue: 7 Pages: 1019-1021
  • DOI: 10.1246/cl.150322
  • NAID: 130005085171
  • Peer Reviewed / Open Access
• [Journal Article] 2,2,3,3-Tetrafluoronickelacyclopentanes Generated via the Oxidative Cyclization of Tetrafluoroethylene and Simple Alkenes: A Key Intermediate in Nickel-Catalyzed C-C Bond-Forming Reactions (2015)
  • Author(s): Ohashi, M.; Kawashima, T.; Taniguchi, T. O.; Kikushima, K.; Ogoshi, S.
  • Journal Title: Organometallics Volume: 34 Issue: 9 Pages: 1604-1607
  • DOI: 10.1021/acs.organomet.5b00218
  • Peer Reviewed
• [Journal Article] Aza-nickelacycle key intermediate in nickel(0)-catalyzed transformation reactions (2015)
  • Author(s): Ohashi, M.; Hoshimoto, Y.; Ogoshi, S.
  • Journal Title: Dalton Transactions Volume: 44 Issue: 27 Pages: 12060-12073
  • DOI: 10.1039/c5dt00640f
  • Peer Reviewed
• [Presentation] 高反応性分子会合体を触媒、H2/CO/CO2混合ガスをH2源として用いたカルボニル化合物の水素化反応 (2019)
  • Author(s): 櫻羽真熙、星本陽一、生越專介
  • Organizer: 日本化学会 第99春季年会（2019）
• [Presentation] Ni(0)/Chiral Phosphoramidite-Catalyzed Asymmetric Carbonylative Cycloaddition of Ene-Imines with CO (2019)
  • Author(s): Keita Ashida, Yoichi Hoshimoto, Masato Ohashi, Sensuke Ogoshi
  • Organizer: 日本化学会 第99春季年会（2019）
• [Presentation] Hydrogen Purification Based on Catalytic Hydrogenation/Dehydrogenation of N-Heteroaromatics Mediated by Frustrated Lewis Pairs (2019)
  • Author(s): Takahiro Asada, Yoichi Hoshimoto, Sensuke Ogoshi
  • Organizer: 日本化学会 第99春季年会（2019）
• [Presentation] H2/CO/CO2混合ガス雰囲気化におけるカルボニル化合物の触媒的水素化反応 (2018)
  • Author(s): 櫻羽真熙、星本陽一、生越專介
  • Organizer: 第45回有機典型元素化学討論会
• [Presentation] 窒素上にホスフィンオキシドを導入したN-ヘテロ環状カルベンと典型元素または遷移金属から成る錯体の合成および反応性 (2018)
  • Author(s): 木下拓也、櫻羽真熙、大保政貴、Manussada Ratanasak、星本陽一、長谷川淳也、生越専介
  • Organizer: 第45回有機典型元素化学討論会
• [Presentation] 典型元素による含窒素芳香族化合物の触媒的水素化/脱水素化反応を活用した粗水素からの水素精製 (2018)
  • Author(s): 浅田貴大、星本陽一、生越專介
  • Organizer: 第45回有機典型元素化学討論会
• [Presentation] Base Metal-Catalyzed Reactions of Gaseous Reactant Under No Stirring Condition (2018)
  • Author(s): Sensuke Ogoshi
  • Organizer: The International Symposium on Organic Reactions (ISOR-13)
  • Int'l Joint Research / Invited
• [Presentation] Cu(I)-Catalyzed Pentafluoroethylation of Iodoarenes with Tetrafluoroethylene (2018)
  • Author(s): Sensuke Ogoshi
  • Organizer: the 13th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-13)
  • Int'l Joint Research
• [Presentation] PoxIms: Multifunctional multipurpose Carbenes (2018)
  • Author(s): Yoichi Hoshimoto, Takuya Kinoshita, Takahiro Asada, Sunit Hazra, Sensuke Ogoshi
  • Organizer: The 18th JAPAN-KOREA Joint Sumposium on Organometallic and Coordination Chemistry
  • Int'l Joint Research
• [Presentation] 温和な条件下での不活性C-F結合のNi(0)錯体への酸化的付加 (2018)
  • Author(s): 西村知華、Orlando Andrella Nicholas、大橋理人、生越專介
  • Organizer: 第8回CSJ化学フェスタ
• [Presentation] 高反応性分子会合体の反応性制御を鍵とするカルボニル化合物の水素化反応 (2018)
  • Author(s): 櫻羽真熙、星本陽一、生越專介
  • Organizer: 第8回CSJ化学フェスタ
• [Presentation] Enantioselective Synthesis of γ-Lactams via Ni(0)-Catalyzed [2+2+1] Carbonylative Cycloaddition of Ene-Imines (2018)
  • Author(s): Keita Ashida, Yoichi Hoshimoto, Masato Ohashi, Sensuke Ogoshi
  • Organizer: JGP Chem & ChemEn International Workshop: Sustainability-Oriented Organic Synthesis
  • Int'l Joint Research
• [Presentation] Nickel-catalyzed Asymmetric Reaction via Oxidative Cyclization with Full Control over Multiple StereogenicCenters (2018)
  • Author(s): Sensuke Ogoshi
  • Organizer: 28th International Conference on Organometallic Chemistry (ICOMC-2018)
  • Int'l Joint Research / Invited
• [Presentation] Efficient Synthesis of Polycyclic γ-Lactams by Ni(0)-Catalyzed [2+2+1] Cycloaddition of Ene-Imines with Carbon Monoxide (2018)
  • Author(s): Keita Ashida, Yoichi Hoshimoto, Masato Ohashi, Sensuke Ogoshi
  • Organizer: the 28th International Conference on Organometallic Chemistry (ICOMC-2018)
  • Int'l Joint Research
• [Presentation] Strategic Use of N-Phosphine Oxide-Substituted Imidazolylidenes for Phosphorylation of Carbon-Oxygen Bond (2018)
  • Author(s): Takahiro Asada, Sunit Hazra, Yoichi Hoshimoto, Sensuke Ogoshi
  • Organizer: the 28th International Conference on Organometallic Chemistry (ICOMC-2018)
  • Int'l Joint Research
• [Presentation] Nickel or Cupper-Catalyzed Reactions of Gaseous Reactant Under No Stirring Condition (2018)
  • Author(s): Sensuke Ogoshi
  • Organizer: 21st International Symposium on Homogeneous Catalysis
  • Int'l Joint Research / Invited
• [Presentation] Ni触媒を用いたエンインのポーソンカーン反応及び環化異性化反応 (2018)
  • Author(s): 西村知華、大西輝、星本陽一、大橋理人、生越專介
  • Organizer: 第51回有機金属若手の会 夏の学校
• [Presentation] キノリン誘導体の効率的な水素化を指向した新規有機ホウ素の合成 (2018)
  • Author(s): 浅田貴大、星本陽一、生越專介
  • Organizer: 第51回有機金属若手の会 夏の学校
• [Presentation] FLP触媒MHBの開発と反応性 (2018)
  • Author(s): 櫻羽真熙、星本陽一、生越專介
  • Organizer: 第51回有機金属若手の会 夏の学校
• [Presentation] 普遍金属を利用するテトラフルオロエチレンの1,2-官能基化 (2018)
  • Author(s): 生越專介
  • Organizer: 創薬懇話会2018
  • Invited
• [Presentation] 二酸化炭素からの非対称ケトンの直接合成を指向したN-ヘテロ環状カルベンの活用 (2018)
  • Author(s): 浅田貴大、星本陽一、生越專介
  • Organizer: 第7回JACI/GSCシンポジウム
• [Presentation] Ni-NHC 錯体によるC-F 結合切断反応 (2018)
  • Author(s): 生越專介
  • Organizer: 新学術領域研究「精密制御反応場」 第２回全体会議・第５回公開シンポジウムプログラム
• [Presentation] Ni(0)/NHC 錯体を用いた炭素-フッ素結合切断反応 (2018)
  • Author(s): 井宮弘人、Andrella Nicholas Orlando、星本陽一、大橋理人、生越専介
  • Organizer: 日本化学会 第98春季年会 (2018)
• [Presentation] Phosphorylation of Carbon-Oxygen Bond with N-Phosphine Oxide-Substituted Imidazolylidenes (2018)
  • Author(s): ASADA,Takahiro; HAZRA, Sunit; HOSHIMOTO, Yoichi; OGOSHI, Sensuke
  • Organizer: 日本化学会 第98春季年会 (2018)
• [Presentation] Ni(0)触媒を用いたエンインのポーソンカーン反応及び環化異性化反応 (2018)
  • Author(s): 西村知華、大西輝、星本陽一、大橋理人、生越専介
  • Organizer: 日本化学会 第98春季年会 (2018)
• [Presentation] 6員環アザニッケルエノラートを経由するシクロプロピルイミン類の変換反応 (2018)
  • Author(s): 植田雄剛、玉置喬士、星本陽一、大橋 理人、生越専介
  • Organizer: 日本化学会 第98春季年会 (2018)
• [Presentation] C(sp3)－F Bond Cleavage of α-Fluorocarbonyl Compounds with Ni(0)/NHC Complex (2017)
  • Author(s): Tinghui, Y.; Sakaguchi, H.; Ohashi, M.; Ogoshi, S.
  • Organizer: 日本化学会 第97春季年会 (2017)
  • Place of Presentation: 慶応義塾大学日吉キャンパス（神奈川県、横浜市）
  • Year and Date: 2017-03-18
• [Presentation] 窒素上にホスフィンイミドを有するN-ヘテロ環状カルベンとLewis酸との反応 (2017)
  • Author(s): 日野上貴哉、Hazra Sunit、星本陽一、大橋理人、生越専介
  • Organizer: 日本化学会 第97春季年会 (2017)
  • Place of Presentation: 慶応義塾大学日吉キャンパス（神奈川県、横浜市）
  • Year and Date: 2017-03-17
• [Presentation] Controlling Generation of Frustrated Lewis Pairs from Carbene-Borane Complexes: Mechanism and Application (2017)
  • Author(s): Kinoshita, T.; Hoshimoto, Y.; Ohashi, M.; Ogoshi, S.
  • Organizer: 日本化学会 第97春季年会 (2017)
  • Place of Presentation: 慶応義塾大学日吉キャンパス（神奈川県、横浜市）
  • Year and Date: 2017-03-17
• [Presentation] 窒素上のアリール基にスルホニル基を導入したN-ヘテロ環状 カルベンの合成 (2017)
  • Author(s): 石本和也、KUMAR Ravindra、星本陽 一、大橋理人、生越専介
  • Organizer: 日本化学会 第97春季年会 (2017)
  • Place of Presentation: 慶応義塾大学日吉キャンパス（神奈川県、横浜市）
  • Year and Date: 2017-03-17
• [Presentation] Strategic Utilization of N-Phosphine Oxide-Substituted Imidazolylidenes for Transformation of Carbonyl Compounds (2017)
  • Author(s): HAZRA, S.; HOSHIMOTO, Y.; ASADA, T.; OHASHI, M.; Ogoshi, S.
  • Organizer: 日本化学会 第97春季年会 (2017)
  • Place of Presentation: 慶応義塾大学日吉キャンパス（神奈川県、横浜市）
  • Year and Date: 2017-03-17
• [Presentation] 高反応性ルイス酸-塩基会合体を触媒、水素を還元剤とするアミンの還元的アルキル化 (2017)
  • Author(s): 木下拓也、星本陽一、生越専介
  • Organizer: 第44回有機典型元素化学討論会
• [Presentation] 窒素上にホスフィンオキシドを有するN-ヘテロ環状カルベンを用いたNi錯体の合成と反応性 (2017)
  • Author(s): 山内泰宏、木下拓也、星本陽一、大橋理人、生越専介
  • Organizer: 第44回有機典型元素化学討論会
• [Presentation] ホスフィンイミドを導入した新規N-ヘテロ環状カルベンの合成と反応性に関する研究 (2017)
  • Author(s): 日野上貴哉、星本陽一、生越專介
  • Organizer: 第44回有機典型元素化学討論会
• [Presentation] 遷移金属フリーかつ水素を還元剤とするアミンの触媒的還元的アルキル化 (2017)
  • Author(s): 木下拓也、星本陽一、生越專介
  • Organizer: 第10回有機触媒シンポジウム
• [Presentation] Enantioselective Desymmetrization Strategy by Oxidative Cyclization on Nickel: Expedient Access to Fused Tricyclic Scaffolds (2017)
  • Author(s): Sensuke Ogoshi, Ravindra Kumar, Yoichi Hoshimoto, Masato Ohashi
  • Organizer: The12th International Conference on Cutting-edge Organic Chemistry inAsia (ICCEOCA-12)
  • Int'l Joint Research
• [Presentation] 新規N-ヘテロ環状カルベン-ルイス酸錯体の合成と反応性に関する研究 (2017)
  • Author(s): 日野上貴哉、Hazra Sunit、星本陽一、大橋理人、生越專介
  • Organizer: 第7回CSJフェスタ2017
• [Presentation] Ni(0)触媒を用いたイミンとアルケン、一酸化炭素との [2+2+1] 不斉環化付加反応による多環式γ-ラクタム合成 (2017)
  • Author(s): 芦田慶太、David E. Scott、星本陽一、大橋理人、生越専介
  • Organizer: 第47回複素環化学討論会
• [Presentation] 0価ニッケル触媒を用いたエン－イミンと一酸化炭素との[2+2+1]不斉環化付加反応 (2017)
  • Author(s): 芦田慶太、David. E. Scott、星本陽一、大橋理人、生越専介
  • Organizer: 第64回有機金属化学討論会
• [Presentation] Transformation of Tetrafluoroethylene by Ubiquitous Metal. Isolation and Reactivity of Intermediate Complexes (2017)
  • Author(s): Sensuke Ogoshi
  • Organizer: the 19th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis(OMCOS19)
  • Int'l Joint Research
• [Presentation] Ni(0)-Catalyzed Intramolecular [2+2+1] Cycloaddition of Ene-Imines with Carbon Monoxide Leading to Polycyclic γ-Lactams (2017)
  • Author(s): Keita Ashsida, Yoichi Hoshimoto, Masato Ohashi, Sensuke Ogoshi
  • Organizer: the 19th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis(OMCOS19)
  • Int'l Joint Research
• [Presentation] Mechanistic Studies on Thermal Revival of Frustrated Lewis Pairs from Carbene-Borane Complexes (2017)
  • Author(s): Takuya Kinoshita, Sunit Hazra, Yoichi Hoshimoto, Sensuke Ogoshi
  • Organizer: The 12th International Conference of Heteroatom Chemistry(ICHAC-12)
  • Int'l Joint Research
• [Presentation] 窒素上にホスフィンイミドを有したN-ヘテロ環状カルベンとルイス酸の反応 (2016)
  • Author(s): 日野上貴哉、Hazra Sunit、星本陽一、大橋理人、生越専介
  • Organizer: 第43回有機典型元素化学討論会
  • Place of Presentation: 仙台市民会館（宮城県、仙台市）
  • Year and Date: 2016-12-09
• [Presentation] 熱刺激感応性カルベン-ボラン錯体からのFrustrated Lewis Pair発生機構研究 (2016)
  • Author(s): 木下拓也、星本陽一、大橋理人、生越専介
  • Organizer: 第43回有機典型元素化学討論会
  • Place of Presentation: 仙台市民会館（宮城県、仙台市）
  • Year and Date: 2016-12-09
• [Presentation] 二酸化炭素からのカルボン酸-リン酸混合酸無水物の直接合成を指向したN-ヘテロ環状カルベンの活用 (2016)
  • Author(s): 浅田貴大、Sunit Hazra、星本陽一、大橋理人、生越専介
  • Organizer: 第43回有機典型元素化学討論会
  • Place of Presentation: 仙台市民会館（宮城県、仙台市）
  • Year and Date: 2016-12-08
• [Presentation] 窒素上にホスフィンイミドを導入したN-ヘテロ環状カルベンの開発 (2016)
  • Author(s): 日野上貴哉、星本陽一、大橋理人、生越専介
  • Organizer: 第6回CSJ化学フェスタ2016
  • Place of Presentation: タワーホール船橋（東京都、江戸川区）
  • Year and Date: 2016-11-16
• [Presentation] フルオロアルキル鎖とπ―ベンジル構造を有するニッケラサイクルの反応性 (2016)
  • Author(s): 上田雄大、菊嶌孝太郎、大橋理人、生越専介
  • Organizer: 第6回CSJ化学フェスタ2016
  • Place of Presentation: タワーホール船橋（東京都、江戸川区）
  • Year and Date: 2016-11-14
• [Presentation] ケイ素－フッ素間の親和性を活用した触媒的脱フッ素水素化反応 (2016)
  • Author(s): 菊嶌孝太郎、大橋理人、生越專介
  • Organizer: 第20回ケイ素化学協会シンポジウム
  • Place of Presentation: 安芸グランドホテル（広島県、廿日市市）
  • Year and Date: 2016-10-07
• [Presentation] 触媒量のフッ化物塩を用いたシリルチオフェン誘導体の分子変換反応 (2016)
  • Author(s): 菊嶌孝太郎、山内泰宏、前田恭吾、大橋理人、生越専介
  • Organizer: 第46回複素環化学討論会
  • Place of Presentation: 金沢歌劇座（石川県、金沢市）
  • Year and Date: 2016-09-27
• [Presentation] 銅触媒によるフルオロアルケンの脱フッ素ケイ素化反応 (2016)
  • Author(s): 阪口博信、菊嶌孝太郎、大橋理人、生越専介
  • Organizer: 第63回有機金属化学討論会
  • Place of Presentation: 早稲田大学西早稲田キャンパス（東京都、新宿区）
  • Year and Date: 2016-09-14
• [Presentation] Chemoselective Cross-Trimerization Reaction of Tetrafluoroethylene, Ethylene, and Aldehydes via Nickelacycle Keyintermediate (2016)
  • Author(s): Shirataki, H.; Kikushima, K.; Ohashi, M.; Ogoshi, S.
  • Organizer: the 27th International Conference on Organometallic Chemistry (ICOMC 2016)
  • Place of Presentation: Melbourne Convention and Exhibition Centre (Melborne, Australia)
  • Year and Date: 2016-07-21
  • Int'l Joint Research
• [Presentation] Direct Preparation of Carboxylic-Phosphinic Mixed Anhydride from Carbon Dioxide and N-Phosphine Oxide Substituted Imidazolylidene (2016)
  • Author(s): Asada, T.; Hoshimoto, Y.; Ogoshi, S.
  • Organizer: XXVII European Colloquium on Heterocyclic Chemistry(ECHC2016)
  • Place of Presentation: NH City Center Amsterdam (Amsterdam, The Netherlands)
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] REVIVAL OF FRUSTRATED LEWIS PAIRS FROM SHELF-STABLE CARBENE-BORANE COMPLEXES (2016)
  • Author(s): Kinoshita, T.; Hoshimoto, Y.; Ogoshi, S.
  • Organizer: XXVII European Colloquium on Heterocyclic Chemistry(ECHC2016)
  • Place of Presentation: NH City Center Amsterdam (Amsterdam, The Netherlands)
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] ニッケルと不飽和化合物だけで組み上げる有機合成 (2016)
  • Author(s): 生越專介
  • Organizer: 平成28年度 前期（春季）有機合成化学講習会
  • Place of Presentation: 日本薬学会長井記念館長井記念ホール（東京都、渋谷区）
  • Year and Date: 2016-06-15
  • Invited
• [Presentation] Ni(0)-Catalyzed Intramolecular Reductive Coupling of Aldehydes and Alkenes with Hydrosilanes (2016)
  • Author(s): Hayashi, Y.; Hoshimoto, Y.; Ohashi, M.; Ogoshi, S.
  • Organizer: Osaka-CCHF Joint Workshop on C-H Bond Activation
  • Place of Presentation: Hankyu Terminal Square (Osaka, Japan)
  • Year and Date: 2016-06-14
  • Int'l Joint Research
• [Presentation] 配位子の自由度制御を鍵とする感応性錯体を用いた合成反応開発 (2016)
  • Author(s): 星本陽一、生越專介
  • Organizer: 新学術領域研究「感応性化学種が拓く新物質科学」第６回公開シンポジウム
  • Place of Presentation: 広島大学東広島キャンパス（広島県、東広島市）
  • Year and Date: 2016-05-20
• [Presentation] 窒素上にホスフィンオキシドを有するN-ヘテロ環状カルベンと二酸化炭素の反応によるカルボン酸-リン酸混合酸無水物の合成 (2016)
  • Author(s): 浅田貴大、星本陽一、生越専介
  • Organizer: 新学術領域研究「感応性化学種が拓く新物質科学」第６回公開シンポジウム
  • Place of Presentation: 広島大学東広島キャンパス（広島県、東広島市）
  • Year and Date: 2016-05-20
• [Presentation] 熱刺激感応性ルイス酸・塩基錯体からのFrustrated Lewis Pair発生の制御 (2016)
  • Author(s): 木下拓也、星本陽一、生越専介
  • Organizer: 新学術領域研究「感応性化学種が拓く新物質科学」第６回公開シンポジウム
  • Place of Presentation: 広島大学東広島キャンパス（広島県、東広島市）
  • Year and Date: 2016-05-20
• [Presentation] Asymmetric Synthesis of Benzoxasiloles via η2-Aldehyde Chiral Nickel(0) Complex and Reaction Path (2016)
  • Author(s): Ogoshi, S.
  • Organizer: Pre-ISOR Symposium
  • Place of Presentation: Kyoto University (Kyoto, Japan)
  • Year and Date: 2016-04-21
  • Int'l Joint Research
• [Presentation] Asymmetric Synthesis of Benzoxasiloles via η2-Aldehyde Chiral Nickel(0) Complex and Reaction Path (2016)
  • Author(s): Ogoshi, S
  • Organizer: UK Japanese Asymmetric Catalysis Symposium
  • Place of Presentation: Ｔhe University of Manchester, UK
  • Year and Date: 2016-03-13
  • Int'l Joint Research / Invited
• [Presentation] 容積可変反応場の設計と構築 (2016)
  • Author(s): 生越 専介
  • Organizer: 新学術領域研究「精密制御反応場」第1回公開シンポジウム
  • Place of Presentation: 東京工業大学蔵前会館
  • Year and Date: 2016-01-30
• [Presentation] Transformation of tetrafluoroethylene via transition metal intermediates (2015)
  • Author(s): Ogoshi, S
  • Organizer: 2015 International Chemical Congress of Pacific Basin Societies
  • Place of Presentation: Hilton Hawaiian Village, America
  • Year and Date: 2015-12-17
  • Int'l Joint Research / Invited
• [Presentation] Nickel(0)-catalyzed transformation reactions via aza-nickelacycle intermediates (2015)
  • Author(s): Ogoshi, S
  • Organizer: 2015 International Chemical Congress of Pacific Basin Societies
  • Place of Presentation: Hilton Hawaiian Village, America
  • Year and Date: 2015-12-16
  • Int'l Joint Research / Invited
• [Presentation] 有機金属化学が可能にする合成反応設計 (2015)
  • Author(s): 生越 専介
  • Organizer: 第70回記念有機合成化学協会関東支部シンポジウム
  • Place of Presentation: 長岡工業高等専門学校
  • Year and Date: 2015-11-22
  • Invited
• [Presentation] Asymmetric Synthesis of Benzoxasiloles via η2-Aldehyde Chiral Nickel(0) Complex and Reaction Path (2015)
  • Author(s): Ogoshi, S
  • Organizer: ICCEOCA-10 / ARN-CEOCA-1
  • Place of Presentation: 85 Sky Tower Hotel, Taiwan
  • Year and Date: 2015-11-02
  • Int'l Joint Research
• [Presentation] Nickel-Catalzed Transformation of Carbonyl Compounds via Hetero-Nickelacycle Intermediates (2015)
  • Author(s): Ogoshi, S
  • Organizer: XVII Organic Chemistry Conference
  • Place of Presentation: Hotel Le Meridien, India
  • Year and Date: 2015-10-27
  • Int'l Joint Research / Invited
• [Presentation] 環状ニッケル中間体を経由する触媒反応-反応設計から機構まで (2015)
  • Author(s): 生越 専介
  • Organizer: 新学術領域 若手セミナー
  • Place of Presentation: 名古屋 金山研修センター
  • Year and Date: 2015-10-03
  • Invited
• [Presentation] Transformation of Tetrafluoroethylene via Transition Metal Intermediates (2015)
  • Author(s): Ogoshi, S
  • Organizer: SeleCa-Symposium
  • Place of Presentation: RWTH Aachen University, Germany
  • Year and Date: 2015-09-01
  • Int'l Joint Research / Invited
• [Presentation] Transformation of Tetrafluoroethylene via Transition Metal Intermediates (2015)
  • Author(s): Ogoshi, S
  • Organizer: 9th French-Japanese Seminar on Fluorine
  • Place of Presentation: The University of Nice, France
  • Year and Date: 2015-08-30
  • Int'l Joint Research / Invited
• [Book] Nickel Catalysis in Organic Synthesis (2020)
  • Author(s): Sensuke Ogoshi(ED)
  • Total Pages: 355
  • Publisher: WILEY-VCH
  • ISBN: 9783527344079