Stereoselective Reactions Induced by Supramolecular Catalysts

• Project Area: Precise Formation of a Catalyst Having a Specified Field for Use in Extremely Difficult Substrate Conversion Reactions
• Project/Area Number: 15H05810
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Nagoya University
• Principal Investigator: Ishihara Kazuaki 名古屋大学, 工学研究科, 教授 (40221759)
• Project Period (FY): 2015-06-29 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥43,160,000 (Direct Cost: ¥33,200,000、Indirect Cost: ¥9,960,000); Fiscal Year 2019: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2018: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2017: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2016: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2015: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
• Keywords: 有機化学 / 触媒 / 超分子化学 / 自己組織化 / 化学プロセス / 有機合成 / 酸塩基複合化学 / グリーンケミストリー

Outline of Final Research Achievements

High-performance supramoleular catalysts which can control multi-selectivities have been developed based on acid-base combination chemistry. The two representative results are as follows:
(1) Enantio- and chemoselective Strecker-type reaction was developed by using 1,1'-binaphthyl-2,2'-disulfonic acid (BINSA)-derived supramolecular metal salt catalysts.
(2) Multi-selective Diels-Alder reaction of propargyl aldehydes was developed by using supramolecular Lewis acid-assisted chiral Lewis acid (LLA) catalysts which were talormade for each reaction.

Academic Significance and Societal Importance of the Research Achievements

新規医薬品・機能有機材料の開発には有機合成化学の技術革新が必要不可欠である。この研究成果はこれまで合成が困難であった有機化合物を選択的に合成できることを実証するものであり、本研究を推進していくことで、近い将来、合成したい物質を意のままに合成できるようになることが大いに期待される。物質を意のままに合成できれば、社会に役立つ新しい機能物質の開発に繋がるはずである。同時に、製造方法の革新は地球環境負荷の低減に大いに貢献するものである。

Research Products

• [Int'l Joint Research] University of California, Berkeley(米国)
• [Int'l Joint Research] ICIQ(スペイン)
• [Journal Article] Chemoselective oxidative generation of ortho-quinone methides and tandem transformations (2020)
  • Author(s): Muhammet Uyanik, Kohei Nishioka, Ryutaro Kondo, Kazuaki Ishihara
  • Journal Title: Nat. Chem. Volume: 12 Issue: 4 Pages: 353-362
  • DOI: 10.1038/s41557-020-0433-4
  • Peer Reviewed
• [Journal Article] Radical cation-induced crossed [2 + 2] cycloaddition of electron-deficient anetholes initiated by iron(III) salt (2020)
  • Author(s): Takahiro Horibe, Kei Katagiri, Kazuaki Ishihara
  • Journal Title: Adv. Synth. Catal. Volume: 960–963 Issue: 4 Pages: 960-963
  • DOI: 10.1002/adsc.201901337
  • NAID: 120006845843
  • Peer Reviewed
• [Journal Article] Chemoselective oxidative spiroetherification and spiroamination of arenols using I+/Oxone catalysis (2020)
  • Author(s): Muhamet Uyanik, Naoto Sahara, Outa Katade, Kazuaki Ishihara
  • Journal Title: Org. Lett. Volume: 22 Issue: 2 Pages: 560-564
  • DOI: 10.1021/acs.orglett.9b04324
  • Peer Reviewed
• [Journal Article] Cationic iron(III) salt as an initiator for radical cation-induced [4 + 2] cycloaddition (2020)
  • Author(s): Takahiro Horibe, Shuhei Ohmura, Kei Katagiri, Kazuaki Ishihara
  • Journal Title: Asian J. Org. Chem. Volume: 9 Issue: 3 Pages: 395-398
  • DOI: 10.1002/ajoc.201900749
  • Peer Reviewed
• [Journal Article] Initiators for radical cation-induced [2 + 2]- and [4 + 2]-cycloadditions of electron-rich alkenes (2020)
  • Author(s): Takahiro Horibe, Kazuaki Ishihara
  • Journal Title: Chem. Lett. Volume: 49 Issue: 1 Pages: 107-113
  • DOI: 10.1246/cl.190790
  • NAID: 130007782535
  • Peer Reviewed / Open Access
• [Journal Article] Highly active chiral dilithium(I) binaphthyldisulfonate catalysts for enantio- and chemoselective Strecker-type reactions (2019)
  • Author(s): Manabu Hatano, Kosuke Nishio, Takuya Mochizuki, Keisuke Nishikawa, Kazuaki Ishihara
  • Journal Title: ACS Catal. Volume: 9 Issue: 12 Pages: 8178-8196
  • DOI: 10.1021/acscatal.9b04322
  • Peer Reviewed
• [Journal Article] Enantioselective oxidative coupling reaction of 2-naphthol derivatives catalyzed by chiral diphosphine oxide-iron(II) complexes (2019)
  • Author(s): Takahiro Horibe, Keita Nakagawa, Takashi Hazeyama, Kazuaki Takeda, Kazuaki Ishihara
  • Journal Title: Chem. Commun. Volume: 55 Issue: 91 Pages: 13677-13680
  • DOI: 10.1039/c9cc07834g
  • NAID: 120006786250
  • Peer Reviewed
• [Journal Article] Oxidation of alcohols and amines (2019)
  • Author(s): Muhammet Uyanik, Kazuaki Ishihara
  • Journal Title: Patai’s Chemistry of Functional Groups Volume: なし Pages: 261-306
  • DOI: 10.1002/9780470682531.pat0945
  • Peer Reviewed
• [Journal Article] 塩化鉄(III)を用いた芳香族ラジカルカチオンの単離と反応性 (2019)
  • Author(s): 堀部貴大，大村修平，石原一彰
  • Journal Title: ケミカルエンジニヤリング Volume: 64 Pages: 297-304
  • Peer Reviewed
• [Journal Article] ホウ素Lewis酸-キラルリン酸複合触媒を用いるマルチ選択的[2+2]/[4+2]付加環化反応 (2019)
  • Author(s): 波多野学，石原一彰
  • Journal Title: 化学工業 Volume: 70 Pages: 634-642
  • Peer Reviewed
• [Journal Article] デザイナーC2対称ジアミド型キラルヨードアレーン触媒 (2019)
  • Author(s): ウヤヌク ムハメット、石原 一彰
  • Journal Title: TCIメール Volume: 182 Pages: 2-16
  • Peer Reviewed / Open Access
• [Journal Article] Designer C2-symmetric Chiral Diamide-type Organoiodine Catalysts (2019)
  • Author(s): Muhammet Uyanik and Kazuaki Ishihara
  • Journal Title: TCIMAIL Volume: 182 Pages: 2-14
  • Peer Reviewed / Open Access
• [Journal Article] Regioselective Oxidative Chlorination of Arenols Using NaCl and Oxone (2019)
  • Author(s): Muhammet Uyanik, Naoto Sahara, and Kazuaki Ishihara
  • Journal Title: Eur. J. Org. Chem. Volume: - Issue: 1 Pages: 27-31
  • DOI: 10.1002/ejoc.201801063
  • NAID: 120006623814
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Enantioselective [1,3] O-to-C Rearrangement: Dearomatization of Alkyl 2-Allyloxy/benzyloxy-1/3-naphthoates Catalyzed by a Chiral π-Cu(II) Complex (2019)
  • Author(s): Lu Yao and Kazuaki Ishihara
  • Journal Title: Chem. Sci. Volume: 10 Issue: 8 Pages: 2259-2263
  • DOI: 10.1039/c8sc05601c
  • Peer Reviewed
• [Journal Article] Ammonium Hypoiodite-catalyzed Oxidative Dearomatizative Azidation of Arenols (2019)
  • Author(s): Muhammet Uyanik, Kohei Nishioka, and Kazuaki Ishihara
  • Journal Title: Chem. Lett. Volume: 48 Issue: 4 Pages: 353-356
  • DOI: 10.1246/cl.181036
  • NAID: 130007624439
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Structure and Reactivity of Aromatic Radical Cations Generated by FeCl3 (2019)
  • Author(s): Takahiro Horibe, Shuhei Ohmura, and Kazuaki Ishihara
  • Journal Title: J. Am. Chem. Soc. Volume: 141 Issue: 5 Pages: 1877-1881
  • DOI: 10.1021/jacs.8b12827
  • NAID: 120006643277
  • Peer Reviewed
• [Journal Article] ボロン酸触媒を用いるアミド縮合反応 (2018)
  • Author(s): 石原一彰
  • Journal Title: PETROTECH Volume: 41 Pages: 16-19
  • Peer Reviewed
• [Journal Article] ortho-Substituent Effect on 2,4-Bis(trifluoromethyl)phenylboronic Acid-Catalyzed Dehydrative Condensation between Carboxylic Acids and Amines (2018)
  • Author(s): Ke Wang, Yanhui Lu and Kazuaki Ishihara
  • Journal Title: Chem. Commun. Volume: 54 Issue: 43 Pages: 5410-5413
  • DOI: 10.1039/c8cc02558d
  • Peer Reviewed
• [Journal Article] Enantioselective Halo-oxy- and Halo-azacyclizations Induced by Chiral Amidophosphate Catalysts and Halo-Lewis Acids (2018)
  • Author(s): Yanhui Lu, Hidefumi Nakatsuji, Yukimasa Okumura, Lu Yao, and Kazuaki Ishihara
  • Journal Title: J. Am. Chem. Soc. Volume: 140 Issue: 19 Pages: 6039-6043
  • DOI: 10.1021/jacs.8b02607
  • Peer Reviewed
• [Journal Article] Thiourea-I2 as Lewis Base-Lewis Acid Cooperative Catalysts for Iodochlorination of Alkene with In Situ-Generated I-Cl (2018)
  • Author(s): Takahiro Horibe , Yasutaka Tsuji, and Kazuaki Ishihara
  • Journal Title: ACS Catal. Volume: 8 Issue: 7 Pages: 6362-6366
  • DOI: 10.1021/acscatal.8b01565
  • NAID: 120006529622
  • Peer Reviewed
• [Journal Article] Asymmetric Total Synthesis of (-)-Maldoxin, a Common Biosynthetic Ancestor of the Chloropupukeananin Family (2018)
  • Author(s): Takahiro Suzuki, Soichiro Watanabe, Muhammet Uyanik, Kazuaki Ishihara, Susumu Kobayashi, and Keiji Tanino
  • Journal Title: Org. Lett. Volume: 20 Issue: 13 Pages: 3919-3922
  • DOI: 10.1021/acs.orglett.8b01502
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Enantioselective Aza-Friedel-Crafts Reaction of Furan with α-Ketimino Esters Induced by a Conjugated Double Hydrogen Bond Network of Chiral Bis(phosphoric Acid) Catalysts (2018)
  • Author(s): Manabu Hatano, Haruka Okamoto, Taro Kawakami, Kohei Toh, Hidefumi Nakatsuji, Akira Sakakura and Kazuaki Ishihara
  • Journal Title: Chem. Sci. Volume: 9 Issue: 30 Pages: 6361-6367
  • DOI: 10.1039/c8sc02290a
  • Peer Reviewed / Open Access
• [Journal Article] Pentamethylcyclopentadienyl rhodium(III)-chiral disulfonate hybrid catalysis for enantioselective C-H bond functionalization (2018)
  • Author(s): Satake Shun、Kurihara Takumaru、Nishikawa Keisuke、Mochizuki Takuya、Hatano Manabu、Ishihara Kazuaki、Yoshino Tatsuhiko、Matsunaga Shigeki
  • Journal Title: Nature Catalysis Volume: 1 Issue: 8 Pages: 585-591
  • DOI: 10.1038/s41929-018-0106-5
  • NAID: 120006709286
  • Peer Reviewed
• [Journal Article] Chiral Pyrophosphoric Acid Catalysts for the para-Selective and Eanantioselective Aza-Friedel-Crafts Reaction of Phenols (2018)
  • Author(s): Haruka Okamoto, Kohei Toh, Takuya Mochizuki, Hidefumi Nakatsuji, Akira Sakakura, Manabu Hatano, Kazuaki Ishihara
  • Journal Title: Synthesis Volume: 50 Issue: 23 Pages: 4577-4590
  • DOI: 10.1055/s-0037-1610250
  • Peer Reviewed
• [Journal Article] Synthesis of 1,1′-Spirobiindane-7,7′-Disulfonic Acid and Disulfonimide: Application for Catalytic Asymmetric Aminalization (2018)
  • Author(s): Kurihara Takumaru、Satake Shun、Hatano Manabu、Ishihara Kazuaki、Yoshino Tatsuhiko、Matsunaga Shigeki
  • Journal Title: Chemistry - An Asian Journal Volume: 13 Issue: 17 Pages: 2378-2381
  • DOI: 10.1002/asia.201800341
  • NAID: 120006716317
  • Peer Reviewed
• [Journal Article] Chiral Supramolecular U-Shaped Catalysts Induce the Multiselective Diels-Alder Reaction of Propargyl Aldehyde (2018)
  • Author(s): Manabu Hatano, Tatsuhiro Sakamoto, Tomokazu Mizuno, Yuta Goto, and Kazuaki Ishihara
  • Journal Title: J. Am. Chem. Soc. Volume: 140 Issue: 47 Pages: 16253-16263
  • DOI: 10.1021/jacs.8b09974
  • Peer Reviewed
• [Journal Article] Metal-free transesterification catalyzed by tetramethylammonium methyl carbonate (2018)
  • Author(s): Manabu Hatano, Yuji Tabata, Yurikai Yoshida, Kohei Toh, Kenji Yamashita, Yoshihiro Ogura, Kazuaki Ishihara
  • Journal Title: Green Chem. Volume: 20 Issue: 6 Pages: 1193-1198
  • DOI: 10.1039/c7gc03858e
  • NAID: 120006486777
  • Peer Reviewed
• [Journal Article] Boron Tribromide‐Assisted Chiral Phosphoric Acid Catalysts for Enantioselective [2+2] Cycloaddition (2018)
  • Author(s): Tatsuhiro Sakamoto, Takuya Mochizuki, Yuta Goto, Manabu Hatano, Kazuaki Ishihara
  • Journal Title: Chem. Asian J Volume: 13 Issue: 17 Pages: 2373-2377
  • DOI: 10.1002/asia.201800351
  • Peer Reviewed
• [Journal Article] Broensted Acid/Lewis Base Hybrid Complexes (2018)
  • Author(s): Manabu Hatano, Kazuaki Ishihara
  • Journal Title: Top. Organomet. Chem. Volume: 62 Pages: 91-120
  • DOI: 10.1007/3418_2015_143
  • ISBN: 9783319708041, 9783319708065
  • Peer Reviewed
• [Journal Article] Design of boronic acid-base complexes as reusable homogeneous catalysts in dehydrative condensations between carboxylic acids and amines (2017)
  • Author(s): Yanui Lu, Ke Wang, Kazuaki Ishihara
  • Journal Title: Asian J. Org. Chem. Volume: 6 Issue: 9 Pages: 1191-1194
  • DOI: 10.1002/ajoc.201700194
  • Peer Reviewed
• [Journal Article] Enantioselective cycloaddition of styrenes with aldimines catalyzed by a chiral magnesium potassium binaphthyldisulfonate cluster as a chiral Broensted acid catalyst (2017)
  • Author(s): Manabu Hatano, Keisuke Nishikawa, Kazuaki Ishihara
  • Journal Title: J. Am. Chem. Soc. Volume: 139 Issue: 25 Pages: 8424-8427
  • DOI: 10.1021/jacs.7b04795
  • Peer Reviewed
• [Journal Article] Enantioselective conjugate hydrocyanation of α,β-unsaturated N-acylpyrroles catalyzed by chiral lithium(I) phosphoryl phenoxide (2017)
  • Author(s): Manabu Hatano, Katsuya Yamakawa, Kazuaki Ishihara
  • Journal Title: ACS Catal. Volume: 7 Issue: 10 Pages: 6686-6690
  • DOI: 10.1021/acscatal.7b02551
  • Peer Reviewed
• [Journal Article] Chiral hypervalent organoiodine-catalyzed enantioselective oxidative spirolactonization of naphthol derivatives (2017)
  • Author(s): Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara
  • Journal Title: J. Org. Chem. Volume: 82 Issue: 22 Pages: 11946-11953
  • DOI: 10.1021/acs.joc.7b01941
  • Peer Reviewed
• [Journal Article] Selenium-Iodine Cooperative Catalyst for Chlorocyclization of Tryptamine Derivatives (2017)
  • Author(s): Horibe Takahiro、Ohmura Shuhei、Ishihara Kazuaki
  • Journal Title: Organic Letters Volume: 19 Issue: 20 Pages: 5525-5528
  • DOI: 10.1021/acs.orglett.7b02613
  • Peer Reviewed
• [Journal Article] Enantioselective Aza-Friedel-Crafts Reaction of Indoles with Ketimines Catalyzed by Chiral Potassium Binaphthyldisulfonates (2017)
  • Author(s): Manabu Hatano, Takuya Mochizuki, Keisuke Nishikawa, Kazuaki Ishihara
  • Journal Title: ACS Catal. Volume: 8 Issue: 1 Pages: 349-353
  • DOI: 10.1021/acscatal.7b03708
  • Peer Reviewed
• [Journal Article] Enantioselective synthesis of masked benzoquinones using designer chiral hypervalent organoiodine(III) catalysis (2017)
  • Author(s): Muhammet Uyanik, Niiha Sasakura, Masahiro Mizuno, Kazuaki Ishihara
  • Journal Title: ACS Catal. Volume: 7 Issue: 1 Pages: 872-876
  • DOI: 10.1021/acscatal.6b03380
  • Peer Reviewed
• [Journal Article] 4,5-Dimethyl-2-iodoxybenzenesulfonic acid-catalyzed highly site-selective oxidation of 2-substituted phenols to 1,2-quinols (2017)
  • Author(s): Muhammet Uyanik, Tatsuya Mutsuga, Kazuaki Ishihara
  • Journal Title: Angew. Chem. Int. Ed. Volume: 56 Pages: 3956-3960
  • Peer Reviewed
• [Journal Article] Ammonium hypoiodide-catalyzed peroxidative dearomatization of phenols (2017)
  • Author(s): Muhammet Uyanik, Kohei Nishioka, Kazuaki Ishihara
  • Journal Title: Heterocycles Volume: 95 Issue: 2 Pages: 1132-1147
  • DOI: 10.3987/com-16-s(s)84
  • Peer Reviewed
• [Journal Article] 酸塩基複合化学に立脚する高機能触媒の創製 (Design of High Performance Catalysts Based on Acid-Base Combination Chemistry) (2017)
  • Author(s): 石原一彰
  • Journal Title: 有機合成化学協会誌 Volume: 75 Pages: 98-110
  • Peer Reviewed
• [Journal Article] Enantioselective Diels-Alder Reaction Induced by Chiral Supramolecular Lewis Acid Catalysts Based on CN-B and PO-B Coordination Bonds (2016)
  • Author(s): Manabu Hatano, Kazushi Hayashi, Tatsuhiro Sakamoto, Yuma Makino, Kazuaki Ishihara
  • Journal Title: Synlett Volume: 27 Issue: 07 Pages: 1061-1067
  • DOI: 10.1055/s-0035-1561362
  • NAID: 120005946823
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Enantioselective Bromocyclization of 2-Gernaylphenols Induced by Chiral Phosphite-Urea Bifunctional Catalysts (2016)
  • Author(s): Yasuhiro Sawamura, Yoshihiro Ogura, Hidefumi Nakatsuji, Akira Sakakura, Kazuki Ishihara
  • Journal Title: Chem. Commun. Volume: 52 Issue: 36 Pages: 6068-6071
  • DOI: 10.1039/c6cc00229c
  • Peer Reviewed
• [Journal Article] Regioselective 1,4- and 1,6-conjugate additions of Grignard reagent-derived organozinc(II)ates to poly-conjugated esters (2016)
  • Author(s): Manabu Hatano, Mai Mizuno, Kazuaki Ishihara
  • Journal Title: Org. Lett. Volume: 18 Issue: 18 Pages: 4462-4465
  • DOI: 10.1021/acs.orglett.6b01774
  • Peer Reviewed
• [Journal Article] キラルビナフチルジスルホン酸(BINSA)を用いる精密分子設計 (2016)
  • Author(s): 波多野学、石原一彰
  • Journal Title: 化学工業 Volume: 67 Pages: 660-667
• [Journal Article] 【特集】ヨウ素触媒の開発最前線 寄稿「キラル第四級アンモニウム次亜ヨウ素酸塩触媒(Chiral Quaternary Ammonium Hypoiodite Catalysis)」 (2016)
  • Author(s): Muhammet Uyanik, 石原一彰
  • Journal Title: 月刊ファインケミカル Volume: 45 Pages: 16-24
• [Journal Article] Remote Tris(pentafluorophenyl)borane-Assisted Chiral Phosphoric Acid Catalysts for the Enantioselective Diels-Alder Reaction (2016)
  • Author(s): Manabu Hatano, Hideyuki Ishihara, Yuta Goto, Kazuaki Ishihara
  • Journal Title: Synlett Volume: 27 Issue: 04 Pages: 564-570
  • DOI: 10.1055/s-0035-1560369
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Structurally defined molecular hypervalent iodine catalysts for intermolecular enantioselective reactions (2016)
  • Author(s): Stefan Haubenreisser, Thorsten H. Wöste, Claudio Martínez, Kazuaki Ishihara, Kilian Muñiz
  • Journal Title: Angew. Chem. Int. Ed. Volume: 55 Issue: 1 Pages: 413-417
  • DOI: 10.1002/anie.201507180
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Boronic Acid–DMAPO Cooperative Catalysis for Dehydrative Condensation between Carboxylic Acids and Amines (2016)
  • Author(s): Kazuaki Ishihara and Yanhui Lu
  • Journal Title: Chem. Sci. Volume: 7 Issue: 2 Pages: 1276-1280
  • DOI: 10.1039/c5sc03761a
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Enantioselective Cyanosilylation of Ketones with Lithium(I) Dicyanotrimethylsilicate(IV) Catalyzed by a Chiral Lithium(I) Phosphoryl Phenoxide (2016)
  • Author(s): Manabu Hatano, Katsuya Yamakawa, Tomoaki Kawai, Takahiro Horibe, Kazuaki Ishihara
  • Journal Title: Angew. Chem. Int. Ed. Volume: 55 Issue: 12 Pages: 4021-4025
  • DOI: 10.1002/anie.201510682
  • Peer Reviewed
• [Journal Article] 【特集】不斉合成の進展と最新研究: “リン酸の酸・塩基協奏機能を活用したホウ素Lewis酸-キラルリン酸複合高活性触媒の開発(Development of Highly Active Boron Lewis Acid-Assisted Chiral Phosphoric Acid Catalysts Based on the Cooperative Acid-Base Functions)” (2016)
  • Author(s): 波多野学、石原一彰
  • Journal Title: 月刊ファインケミカル Volume: 45 Pages: 24-32
  • Peer Reviewed
• [Journal Article] C- and N-Selective Grignard Addition Reactions of α-Aldimino Esters in the Presence or Absence of Zinc(II) Chloride: Synthetic Applications to Optically Active Azacycles (2015)
  • Author(s): Manabu Hatano, Kenji Yamashita, Kazuaki Ishihara
  • Journal Title: Org. Lett. Volume: 17 Issue: 10 Pages: 2412-2415
  • DOI: 10.1021/acs.orglett.5b00927
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Boron Tribromide-Assisted Chiral Phosphoric Acid Catalyst for a Highly Enantioselective Diels-Alder Reaction of 1,2-Dihydropyridines (2015)
  • Author(s): Manabu Hatano, Yuta Goto, Atsuto Izumiseki, Matsujiro Akakura, Kazuaki Ishihara
  • Journal Title: J. Am. Chem. Soc. Volume: 137 Issue: 42 Pages: 13472-13475
  • DOI: 10.1021/jacs.5b08693
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Enantioselective Cyano-Alkoxycarbonylation of α-Oxoesters Promoted by Brønsted Acid–Lewis Base Cooperative Catalysts (2015)
  • Author(s): Kazuaki Ishihara* and Yoshihiro Ogura
  • Journal Title: Organic Letters Volume: 17 Issue: 24 Pages: 6070-6073
  • DOI: 10.1021/acs.orglett.5b03093
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] アルキルZ 試薬：亜鉛(II)アート錯体を用いるケトン及びイミノエステルへの高効率Grignard付加反応の開発 (2015)
  • Author(s): 波多野学、石原一彰
  • Journal Title: 和光純薬時報 Volume: 83 Pages: 2-5
  • Peer Reviewed
• [Journal Article] 高機能触媒の超分子設計 (2015)
  • Author(s): 波多野学、石原一彰
  • Journal Title: 化学工業 Volume: 66 Pages: 381-388
  • NAID: 40020466231
  • Peer Reviewed
• [Journal Article] Stereoselective Electrophilic Cyclization (2015)
  • Author(s): Akira Sakakura, Kazuaki Ishihara
  • Journal Title: The Chemical Record Volume: 15 Issue: 4 Pages: 728-742
  • DOI: 10.1002/tcr.201500005
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] ハロゲン結合を利用する触媒反応の開発 (2020)
  • Author(s): 石原一彰
  • Organizer: 日本薬学会第140年会
  • Invited
• [Presentation] ヨウ素を触媒や反応剤に用いる反応開発 (2019)
  • Author(s): 石原一彰
  • Organizer: CIRICセミナー No. 2「ハロゲン結合の化学 ～ヨウ素の高度利用をめざして～」
  • Invited
• [Presentation] キラルπ-Cu(II)触媒を用いるエナンチオ選択的α-フッ素化反応 (2019)
  • Author(s): 石原一彰
  • Organizer: モレキュラーキラリティーシンポジウム2019
• [Presentation] Rational Design of High-Performance Catalysts on Acid-Base Combination Chemistry (2019)
  • Author(s): Kazuaki Ishihara
  • Organizer: Gordon Research Conference, Organic Reactions and Processes, Syntheses and Methods for Efficient and Novel Organic Reactions and Processes
  • Int'l Joint Research / Invited
• [Presentation] Green Catalysis on Esterifcation, Amidation, and Oxidation (2019)
  • Author(s): Kazuaki Ishihara
  • Organizer: TCIA 2019 Taiwan Chemistry Forum
  • Int'l Joint Research / Invited
• [Presentation] Development of highly efficient catalytic esterification, amidation, and oxidation (2019)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar (Host: Prof. Jeffrey Chi-Sheng Wu and TCIA), National Taiwan University
  • Int'l Joint Research / Invited
• [Presentation] Enantio- and site-selective α-fluorination of N-acyl-3,5-dimethylpyrazoles catalyzed by chiral π-Cu(II) complexes (2019)
  • Author(s): Kazuaki Ishihara, Kazuki Nishimura, Katsuya Yamakawa
  • Organizer: 1st International Conference of Noncovalent Interractions (ICNI)
  • Int'l Joint Research / Invited
• [Presentation] Enantio- and site-selective α-fluorination of N-acyl-3,5-dimethylpyrazoles catalyzed by chiral π-Cu(II) complexes (2019)
  • Author(s): Kazuaki Ishihara, Kazuki Nishimura, Katsuya Yamakawa
  • Organizer: HALCHEM IX
  • Int'l Joint Research / Invited
• [Presentation] 中分子酸塩基複合触媒の合理的設計 (2019)
  • Author(s): 石原一彰
  • Organizer: 学術講演会、主催：神戸大学大学院工学研究科 界面科学コロキウム、共催：名大鏡友会関西支部
  • Invited
• [Presentation] キラルπ-Cu(II)触媒によるエナンチオ選択的α-フッ素化反応 (2019)
  • Author(s): 石原一彰、西村和揮、山川勝也
  • Organizer: フルオラス科学研究会第12回シンポジウム（名古屋）
• [Presentation] 触媒の匠の挑戦：作れるモノから作りたいモノへ (2019)
  • Author(s): 石原一彰
  • Organizer: テクノフェア名大2019 市民公開セミナー
  • Invited
• [Presentation] 酸塩基複合化学を基盤とする高機能ハロゲン酸化触媒の設計 (2019)
  • Author(s): 石原一彰
  • Organizer: 東京工業大学セミナー
  • Invited
• [Presentation] Chiral Macrocyclic O-Shaped Catalysts for Enantioselective Addition of Lithium Acetylides to Simple Ketones (2019)
  • Author(s): Kazuaki Ishihara, Manabu Hatano, Kenji Yamashita
  • Organizer: 第4回精密制御反応場国際シンポジウム
  • Int'l Joint Research / Invited
• [Presentation] U字型キラル超分し触媒を用いるプロパルギルアルデヒドのマルチ選択的Diels-Alder反応の開発 (2019)
  • Author(s): 波多野学（石原一彰の代理）、阪本竜浩、水野智一、後藤優太、石原一彰
  • Organizer: 第6回公開シンポジウム
  • Invited
• [Presentation] Rational design of high-performace catalysts based on bcid-base combination chemistry (2019)
  • Author(s): Kazuaki Ishihara
  • Organizer: 3rd Edition of International Congress on Catalysis and Chemical Science
  • Int'l Joint Research / Invited
• [Presentation] 反応を自在にあやつる触媒づくりのはなし (2019)
  • Author(s): 石原一彰
  • Organizer: 名古屋大学オープンレクチャー2019
  • Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar (Jiangxi Normal University)
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: 2017 ACP Lectureship Award Lecture (Host: Prof. Ying Yeung Yeung, The Chinese University of Hong Kong)
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: 2017 ACP Lectureship Award Lecture (Host: Prof. Hoi Lun Kwong, City University of Hong Kong)
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: 2017 ACP Lectureship Award Lecture (Host: Ken Cham-Fai Leung, Hong Kong Baptist University)
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of Amidation and Esterification Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: 2017 ACP Lectureship Award Lecture (Host: Prof. Ying Yeung Yeung, Chinese University of Hong Kong)
  • Int'l Joint Research / Invited
• [Presentation] Cooperative System of Chiral Lewis Base Catalysts and Halo-Lewis Acids for Enantioselective Halocyclization (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: ISXB3 (3rd International Symposium on Halogen Bonding)
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of High Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: Special Organic Syntheses Lecture (Host: Prof. Scott A. Snyder)
  • Int'l Joint Research / Invited
• [Presentation] IBS-Catalyzed Oxidation of Alcohols (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: ICHIC 2018 (6th International Conference on Hypervalent Iodine Chemistry)
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: The Mini-Symposium on Boron-catalysed Amidation: from Theory to Practice at Durham University
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: Seminar (Profs. Kilian Muniz and Paolo Melchiorre)
  • Int'l Joint Research / Invited
• [Presentation] 酸塩基複合化学を基盤とする高機能触媒の設計 (2018)
  • Author(s): 石原一彰
  • Organizer: 大日本住友製薬 講演会
  • Invited
• [Presentation] B(C6F5)3を触媒に用いる立体選択的Diels-Alder反応 (2018)
  • Author(s): 石原一彰
  • Organizer: 第11回 フルオラス科学研究会
• [Presentation] 酸塩基複合化学を基盤とする高機能触媒の設計 (2018)
  • Author(s): 石原一彰
  • Organizer: 東京工業大学理工学院応用化学系 有機化学上級第五（医農薬化学）（３年生向け） ホスト：田中健教授
  • Invited
• [Presentation] 触媒をデザインして化学反応を自在に操る (2018)
  • Author(s): 石原一彰
  • Organizer: 滝学園窓口 井戸康貴（進学指導主任）
  • Invited
• [Presentation] 触媒の匠工房 (2018)
  • Author(s): 石原一彰
  • Organizer: テクノフェア名大2018
• [Presentation] かたちあるプロトン酸(H+)触媒を分子設計する (2018)
  • Author(s): 石原一彰
  • Organizer: テクノフェア名大2018
• [Presentation] Rational Design of Novel Chiral Polyprotic Acid Catalysts for Enantioselective Aza-Friedel-Crafts Reactions (2018)
  • Author(s): ○Kazuaki Ishihara, Manabu Hatano, Akira Sakakura, Haruka Okamoto, Taro Kawakami, Kohei Toh, Takuya Mochiuzki, and Hidefumi Nakatsuji
  • Organizer: ICCEOCA-13 (The 13th International Conference on Cutting-Edge Organic Chemistry in Asia)
  • Int'l Joint Research / Invited
• [Presentation] 分子を繋ぐ触媒をデザインする (2018)
  • Author(s): 石原一彰
  • Organizer: 豊西総合大学講座
  • Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: IKCOC-14 (The 14th International Kyoto Conference on New Aspects of Organic Chemistry)
  • Int'l Joint Research
• [Presentation] ボロン酸触媒を用いるカルボン酸の活性化 (2018)
  • Author(s): 石原一彰
  • Organizer: 第11回有機触媒シンポジウム
• [Presentation] ヨウ素触媒を用いる環境低負荷型酸化反応の開発 (2018)
  • Author(s): UYANIK, Muhammet（石原一彰の代理）
  • Organizer: グリーンプロセスインキュベーションコンソーシアム(GIC)平成30年度第59回研修セミナー
  • Invited
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: Peking University Seminar
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: Awarded Lecture of Nankai University Lectureship on Organic Chemistry
• [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: Tianjin University Seminar
• [Presentation] Rational Design of High-Performance Acid-Base Combined Catalysts (2018)
  • Author(s): Kazuaki Ishihara
  • Organizer: The 98th CSJ Annual Meeting
• [Presentation] 触媒の鍵穴制御による高次選択的反応の開発 (2017)
  • Author(s): 石原一彰
  • Organizer: 特別企画講演1S6-04、分子空間化学に基づく精密有機合成・機能展開、日本化学会第97春季年会
  • Place of Presentation: 慶應義塾大学、日吉キャンパス
  • Year and Date: 2017-03-16
  • Invited
• [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: Shanghai Institute of Organic Chemistry Seminar
• [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: East China Normal University Smeinar
• [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: Shanghai Jiao Tong University Seminar
• [Presentation] Rational Design of Chiral Broested Acid Catalysts Based on Acid-Base Combination Chemistry (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: Shanghai Institute of Materia Medica Seminar
• [Presentation] Rational Design of Chiral Boensted Acid Catalysts Based on Acid-Base Combination Chemistry (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: East China University of Science and Technology Seminar
• [Presentation] Rational Design of Chiral Broensted Acid Catalysts for Enantioselective Reactions (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: 2nd International Symposium on Precisely Designed Catalysts with Customized Scaffolding
• [Presentation] Multiselective Diels-Alder Reaction Induced by Chiral Supramolecular Lewis Acid Catalysts (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: KAIST Seminar
• [Presentation] Multiselective Diels-Alder Reaction Induced by Chiral Supramolecular Lewis Acid Catalysts (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: Sogang University Seminar
• [Presentation] Multiselective Diels&-Alder Reaction Induced by Chiral Supramolecular Lewis Acid Catalysts (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: Sungkyunkwan University Seminar
• [Presentation] エステル・アミド縮合触媒及び酸化触媒の開発 (2017)
  • Author(s): 石原一彰
  • Organizer: 第2回「有機分子触媒による高度分子変換技術」講習会
• [Presentation] Chiral Nuclophilic Amidophosphate-catalyzed Enantioselective Iodocyclization (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: 18th Tetrahedron Sympsoium Asia Edition
• [Presentation] Rational Design of Chiral Supramolecular Acid-Base Combined Catalysts (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: Institute of Microbial Chemistry Seminar
• [Presentation] ハロゲンに魅せられて：次世代触媒の研究戦略 (2017)
  • Author(s): 石原一彰
  • Organizer: あいちサイエンスフェスティバル2017「分子をつなぐキューピット！？」触媒が広げた化学の世界
• [Presentation] 触媒で化学反応を意のままに操る (2017)
  • Author(s): 石原一彰
  • Organizer: テクノ・フェア名大2017
• [Presentation] Rational Design of Tunable Chiral Broensted Acid Catalysts for Enantioselective Reactions (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: Chiral India 2017
• [Presentation] Chiral Nucleophilic Amidophosphate-catalyzed Enantioselective Iodocyclization (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: 1st Singapore Japan Germany Trilateral Symposium on Precision Synthesis & Catalysis
• [Presentation] Boronic Acid-Catalyzed Dehydrative Condensation Reaction Directed towards Peptide Synthesis (2017)
  • Author(s): Kazuaki Ishihara
  • Organizer: The 2nd M&M SYNTHECH Unit International Meeting 2017
• [Presentation] 第四級アンモニウム円触媒を用いるエステル交換反応 (2017)
  • Author(s): 石原一彰
  • Organizer: 特別講演会
  • Place of Presentation: 共栄社化学、奈良
  • Invited
• [Presentation] 強力な研究室を作るためのマネジメント (2016)
  • Author(s): 石原一彰
  • Organizer: 化学ラボラトリーマネジメント ～ブレイクをめざす情報センリャク～、CSJ化学フェスタ
  • Place of Presentation: タワーホール船堀
  • Year and Date: 2016-11-11
  • Invited
• [Presentation] Enantioselective Addition Reactions of 3-Butynoyl-1H-pyrazole Catalyzed by Chiral π-Cu(II) Complexes (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: C&FC 2016 (Catalysis and Fine Chemicals 2016)
  • Place of Presentation: Howard Civil Service International House, Taipei, Taiwan
  • Year and Date: 2016-11-10
  • Int'l Joint Research / Invited
• [Presentation] Enantioselective Addition Reactions of 3-Butynoyl-1H-pyrazole Catalyzed by Chiral π-Cu(II) Complexes (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: Chiral India 2016 (5th International Conference and Exhibition)
  • Place of Presentation: Holiday Inn, Mumbai, India
  • Year and Date: 2016-11-08
  • Int'l Joint Research / Invited
• [Presentation] I(III)-Catalyzed Enantioselective Synthesis of Masked ortho-Benzoquinones and Related Reactions (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: ICHIC 2016 (5th International Conference of Hypervalent Iodine Chemistry)
  • Place of Presentation: Eurotel Victoria, Les Diablerets, Switzerland
  • Year and Date: 2016-07-03
  • Int'l Joint Research / Invited
• [Presentation] Cooperative Activation with Chiral Lewis Base Catalysts and N-Haloimides: Catalytic Enantioselective Iodocyclization (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: 2nd International Symposium on Halogen Bonding (ISXB2)
  • Place of Presentation: Gothenburg, Sweden
  • Year and Date: 2016-06-06
  • Int'l Joint Research / Invited
• [Presentation] 有機反応を自在に操るための酸塩基複合化学 (2016)
  • Author(s): 石原一彰
  • Organizer: 特別講演会
  • Place of Presentation: 協和発酵キリン株式会社 富士リサーチパーク
  • Invited
• [Presentation] フッ素置換基を利用する触媒設計 (2016)
  • Author(s): 石原一彰
  • Organizer: 第13回フッ素相模セミナー
  • Place of Presentation: 相模中央化学研究所 大会議室、神奈川県綾瀬市
  • Invited
• [Presentation] Cooperative Activation with Chiral Lewis Base Catalysts and N-Haloimides: Catalytic Enantioselective Iodocyclization (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar
  • Place of Presentation: Stockholm University
  • Int'l Joint Research / Invited
• [Presentation] Enantioselective iodocyclization reacions induced by chiral Lewis acid-base catalysis (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar
  • Place of Presentation: Ruhr University Bochum
  • Int'l Joint Research / Invited
• [Presentation] Enantioselective iodocyclization reacions induced by chiral Lewis acid-base catalysis (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar
  • Place of Presentation: Westfalische Wilhelms-University Munster
  • Int'l Joint Research / Invited
• [Presentation] 有機反応の立体化学を触媒で自在に制御する (2016)
  • Author(s): 石原一彰
  • Organizer: 平成28年度有機合成化学協会東海支部若手研究者のためのセミナー
  • Place of Presentation: 三重大学新産業創成研究拠点セミナー室
  • Invited
• [Presentation] 分子の匠：分子を意のままにつくりたい (2016)
  • Author(s): 石原一彰
  • Organizer: 2016年度名古屋大学オープンキャンパス
  • Place of Presentation: 化学・生命工学科名古屋大学工学部1号館121講義室
  • Invited
• [Presentation] テーラーメイド触媒の設計 (2016)
  • Author(s): 石原一彰
  • Organizer: 特別講演会
  • Place of Presentation: 高知大学理学部応用理学科
  • Invited
• [Presentation] 酵素を凌駕するテーラーメイド触媒の開発を目指して (2016)
  • Author(s): 石原一彰
  • Organizer: (独)日本学術振興会創造機能化学第116委員会 東海地区講演会
  • Place of Presentation: 名古屋大学東山キャンパス理学南館大講堂（坂田・平田ホール）
  • Invited
• [Presentation] Enantioselective Addition Reactions of 3-Butynoyl-1H-pyrazole Catalyzed by Chiral π-Cu(II) Complexes (2016)
  • Author(s): Kazuaki Ishihara
  • Organizer: The 1st M&M SYNTECH Unit International Meeting 2016
  • Place of Presentation: VBL Hall, Nagoya University
  • Int'l Joint Research / Invited
• [Presentation] 酸塩基複合化学に立脚する高機能触媒の創製 (2016)
  • Author(s): 石原一彰
  • Organizer: 2015年度有機合成化学協会賞（学術的）受賞講演会
  • Place of Presentation: 如水会館スターホール
  • Invited
• [Presentation] エステル・アミド縮合触媒の開発 (2016)
  • Author(s): 石原一彰
  • Organizer: 第5回慶應義塾大学戦略的研究基盤形成支援事業シンポジウム 有機合成化学ー効率化と環境調和性ー
  • Place of Presentation: 慶應義塾大学矢上キャンパス、厚生棟大会議室
  • Invited
• [Presentation] [L-15] Enantioselective halocyclizations induced by chiral base-acid cooperarive catalysis (2015)
  • Author(s): Kazuaki Ishihara
  • Organizer: HALCHEM VII (7th International Meeting on Halogen Chemistry)
  • Place of Presentation: the Jan Dlugosz University in Czestochowa, Poland
  • Year and Date: 2015-09-03
  • Int'l Joint Research / Invited
• [Presentation] 酸塩基複合化学を鍵とするキラル金属塩触媒の設計 (2015)
  • Author(s): 石原一彰
  • Organizer: 有機合成夏期セミナー「明日の有機合成化学」
  • Place of Presentation: 有機合成化学協会関西支部主催, 大阪科学技術センター8Ｆ 中・小ホール
  • Year and Date: 2015-09-01
  • Invited
• [Presentation] [C-3] Design of Supramolecular Catalysts for the Enantio-, Diastereo-, Regio-, and Substrate-Selective Diels-Alder Reaction (2015)
  • Author(s): Kazuaki Ishihara
  • Organizer: 第 39回内藤コンファレス The chemistry of organocatalysts 「有機分子触媒の化学 」
  • Place of Presentation: シャトレーゼ ガトーキングダム サッポロ 札幌市北区東茨戸132番地
  • Year and Date: 2015-07-06
  • Int'l Joint Research / Invited
• [Presentation] ヨウ素触媒及び反応剤を用いる高選択的有機変換反応の開発 (2015)
  • Author(s): 石原一彰
  • Organizer: 第18回ヨウ素学会シンポジウム
  • Place of Presentation: 千葉大学西千葉キャンパス総合校舎
  • Invited
• [Presentation] 酸塩基複合化学を鍵とする触媒活性と選択性の制御 (2015)
  • Author(s): 石原一彰
  • Organizer: 第9回北里化学シンポジウム
  • Place of Presentation: 北里大学白金キャンパス
  • Invited
• [Presentation] O-3 アミド脱水縮合反応に有効なフッ素含有フェニルボロン酸触媒：新たな展開へ (2015)
  • Author(s): 石原一彰、魯彦会
  • Organizer: フルオラス科学研究会第8回シンポジウム
  • Place of Presentation: 清水テルサ（静岡市東部勤労者福祉センター）
• [Presentation] Rational Design of Supramolecular Acid-Base Catalysts (2015)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar
  • Place of Presentation: National Sun Yat-sen University (國立中山大學) (Host: Prof. Mi-Ju Wu), Kaohsiung, Taiwan
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of Supramolecular Acid-Base Catalysts (2015)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar
  • Place of Presentation: National Taiwan Normal University (國立師範大學) (Host: Hsyueh-Liang Wu), Taipei, Taiwa
  • Int'l Joint Research / Invited
• [Presentation] Rational Design of Supramolecular Acid-Base Catalysts (2015)
  • Author(s): Kazuaki Ishihara
  • Organizer: Organic Seminar
  • Place of Presentation: Academia Sinica (中央研究院) (Host: Rong-Jie Chein), Taipei, Taiwan
  • Int'l Joint Research / Invited
• [Presentation] 大学は人生の通過点に過ぎない。その先の夢に向かって、今すべきことを。 (2015)
  • Author(s): 石原一彰
  • Organizer: プチカー（大学・学部を知るワークショップ）
  • Place of Presentation: 愛知県立丹羽高等学校
  • Invited
• [Presentation] Rational Design of Chiral Acid-Base Combined Catalysts (2015)
  • Author(s): Kazuaki Ishihara
  • Organizer: 14th Symposium on Chemical Approach to Chirality
  • Place of Presentation: Morimoto Memorial Hall, Kagurazaka, Tokyo
  • Int'l Joint Research / Invited
• [Presentation] Boronic acid-DMAPO cooperative catalysis for dehydrative condensation of carboxylic acids with amines (2015)
  • Author(s): Kazuaki Ishihara, Yanhui Lu
  • Organizer: Recent Trends in Organocatalysis (#122) [1A], Mid-Pacific Center, Coral 4 (Hilton Hawaiian Village), Pacifichem 2015
  • Place of Presentation: Honolulu, Hawaii, USA
  • Int'l Joint Research / Invited
• [Presentation] ORGN 1172: Enantioselective iodocyclization induced by chiral base-acid cooperative catalysis (2015)
  • Author(s): Kazuaki Ishihara, Hidefumi Nakatsuji
  • Organizer: Recent Trends in Organocatalysis (#122) [1A], Mid-Pacific Center, Coral 4 (Hilton Hawaiian Village), Pacifichem 2015
  • Place of Presentation: Honolulu, Hawaii, USA
  • Int'l Joint Research / Invited
• [Presentation] ORGN 1728: Synthesis of 3,3'-Diaryl-1,1'-binaphthalene-2,2'-disulfonic Acids and Design of Chiral 3,3'-Ar2-BINSA Salt Catalysts (2015)
  • Author(s): Kazuaki Ishihara, Manabu Hatano, Keisuke Nishikawa
  • Organizer: New Organosulfur Chemistry (#436) [3A], Mid-Pacific Center, Sea Pearl Suites 3 & 4 (Hilton Hawaiian Village), Pacifichem 2015
  • Place of Presentation: Honolulu, Hawaii, USA
  • Int'l Joint Research
• [Presentation] 非共有結合性相互作用を鍵とする高機能触媒の設計 (2015)
  • Author(s): 石原一彰
  • Organizer: 日本薬学会関東支部第40回学術講演会「創薬イノベーションを支える最先端サイエンス」
  • Place of Presentation: 長井記念館長井記念ホール
  • Invited
• [Book] 有機分子触媒の開発と工業利用 (2018)
  • Author(s): 石原一彰
  • Total Pages: 330
  • Publisher: シーエムシー出版
  • ISBN: 9784781313238
• [Book] Science of Synthesis: Catalytic Oxidation in Organic Synthesis (2017)
  • Author(s): Muhammet Uyanik, Kazuaki Ishihara
  • Total Pages: 880
  • Publisher: Georg Thieme Verlag KG
• [Book] "Chapter 9: Higher Terpenes and Steroids" In "From biosynthesis to total synthesis: Strategies and tactics for natural products" (2016)
  • Author(s): Kazuaki Ishihara
  • Publisher: Wiley-VCH
• [Book] “Chapter 6. Asymmetric Oxidative Dearomatization Reaction” In "Asymmetric Dearomatization Reactions" (2016)
  • Author(s): Kazuaki Ishihara
  • Publisher: Wiley-VCH
• [Book] "Bifunctional Lewis Base Catalysis with Dual Activation of R-M and C-O (n → σ)" In “Lewis Base Catalysis in Organic Synthesis,” 3 Volumes Set (2016)
  • Author(s): Manabu Hatano, Kazuaki Ishihara
  • Publisher: Wiley-VCH
• [Book] “Lewis Acids” In "Boron Reagents in Synthesis" (2016)
  • Author(s): Manabu Hatano, Kazuaki Ishihara
  • Publisher: American Chemical Society
• [Book] 19.1.5 有機アルミニウム化合物（有機合成実験法ハンドブック 第2版（中井武編集代表）） (2015)
  • Author(s): 石原一彰
  • Total Pages: 1202
  • Publisher: 丸善出版
• [Book] Chapter 2. Alkali Metal (Li, Na, K)-based Catalysts (Sustainable Catalysis : With Non-endangered Metals, Part 1) (2015)
  • Author(s): Manabu Hatano, Kazuaki Ishihara
  • Total Pages: 816
  • Publisher: The Royal Society of Chemistry
• [Remarks] 石原研究室 - Ishihara Group
  • URL: https://www.ishihara-lab.net/
• [Remarks] 【プレスリリース】名古屋大学「ヨウ素を触媒に『キノンメチド』の実用的生成法を開発」
  • URL: http://www.nagoya-u.ac.jp/about-nu/public-relations/researchinfo/upload_images/20200330_engg1.pdf
• [Remarks] 【日本の研究】名古屋大学「ヨウ素を触媒に『キノンメチド』の実用的生成法を開発」
  • URL: https://research-er.jp/articles/view/87686
• [Remarks] 日本の研究「効率的ナノ炭素材料構築のための反応機構解明 」
  • URL: https://research-er.jp/articles/view/77222
• [Remarks] Chem-Station「100年以上未解明だった「芳香族ラジカルカチオン」の構造を解明！」
  • URL: https://www.chem-station.com/blog/2019/03/arc.html
• [Remarks] 石原一彰研究室・Ishihara Group
  • URL: https://www.ishihara-lab.net/
• [Remarks] 石原研究室
  • URL: https://www.ishihara-lab.net
• [Remarks] K. Ishihara Laboratory
  • URL: https://www.facebook.com/kishiharalab/
• [Patent(Industrial Property Rights)] カルボン酸アミド化合物の製造方法及び触媒並びにフロー製造システム (2020)
  • Inventor(s): 石原一彰，堀部貴大
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2020-022753
  • Filing Date: 2020
• [Patent(Industrial Property Rights)] カルボン酸エステル合成用触媒、およびカルボン酸エステルの製造方法 (2020)
  • Inventor(s): 石原一彰，波多野学
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2020-037262
  • Filing Date: 2020
• [Patent(Industrial Property Rights)] カルボン酸エステル合成用触媒、およびカルボン酸エステルの製造方法 (2020)
  • Inventor(s): 石原一彰，波多野学
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2020-036987
  • Filing Date: 2020
• [Patent(Industrial Property Rights)] カルボン酸エステルの製造方法及び触媒 (2017)
  • Inventor(s): 石原一彰、波多野学
  • Industrial Property Rights Holder: 名古屋大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2017-150231
  • Filing Date: 2017
• [Funded Workshop] M&M SYNTECH Unit Organic Seminar of Prof. Scott A. Snyder (The University of Chicago) (2018)
• [Funded Workshop] M&M SYNTECH Unit Organic Seminar of Prof. Qingzhi Gao (Tianjin UNiversity) (2018)
• [Funded Workshop] M&M SYNTECH Unit Organic Seminar of Dr. Yi Xiao (Bristol-Myers Squibb Company) (2018)
• [Funded Workshop] M&M SYNTECH Unit Organic Seminar of Prof. Aaron Aponick (University of Florida) (2018)
• [Funded Workshop] M&M SYNTECH Unit of Organic Seminar of Prof. Philip Mounford (University of Oxford) (2018)
• [Funded Workshop] Organic Seminar of Prof. Jeng-Liang Han (Chung Yan Christian University, Taiwan) (2017)
• [Funded Workshop] Organic Seminar of Prof. Boris J. Nachtsheim (University of Bremen) (2017)
• [Funded Workshop] Organic Seminar of Prof. David A. Nagib (Ohaio State University) (2017)
• [Funded Workshop] Organic Seminar of Prof. Shu-Li You (Shanghai Institute of Organic Chemistry) (2017)
• [Funded Workshop] Organic Seminar of Prof. Ran Homg (Shanghai Institute of Organic Chemistry) (2017)
• [Funded Workshop] Organic Seminar of Dr. Nobuyoshi Yasuda (Merck Research Labs) (2017)
• [Funded Workshop] THE 2nd M&M SYNTHECH Unit International Meeting 2017 (2017)
• [Funded Workshop] HALCHEM VIII (2017)
• [Funded Workshop] Organic Seminar of Prof. Rajeev Prabhakar (2017)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] Organic Seminar of Prof. Prahaladarao Sibi (2017)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] Organic Seminar of Prof. Zhenlei Song (2016)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] Organic Seminar of Prof. Scott E. Denmark (2016)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] Organic Seminar of Dr. Rong-Jie Chein (2016)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] Organic Seminar of Prof. Zhu-Jun Yao (2016)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] The 1st M&M SYNTHECH Unit International Meeting (2016)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] Organic Seimar of Prof. Sarah E. Reisman (USA) (2015)
  • Place of Presentation: 名古屋大学
• [Funded Workshop] Organic Seimar of Prof. Stefan M. Huber (Germany) (2015)
  • Place of Presentation: 名古屋大学