| Budget Amount *help |
¥61,100,000 (Direct Cost: ¥47,000,000、Indirect Cost: ¥14,100,000)
Fiscal Year 2019: ¥12,870,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥2,970,000)
Fiscal Year 2018: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Fiscal Year 2017: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Fiscal Year 2016: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Fiscal Year 2015: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
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| Outline of Final Research Achievements |
We aimed to propose bio-markers for epileptic seizures and also for complex visual hallucinations that patients of dementia with Lewy bodies can see. For this purpose, we established a mathematical theory for self-organization with constraints, and neuro-feedback systems with animals, which detect circular causality between microscopic and macroscopic states of neural activity by means of interactions with environment. Based on these theoretical and experimental frameworks, we found the appearance of dynamical systems with a few degrees of freedom and reduction of fluctuations of power spectrum, which can be bio-markers of epileptic seizures. We also found abnormal synaptic learning in self-reorganization processes, which can provide a neural mechanism of network diseases.
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