Budget Amount *help |
¥44,330,000 (Direct Cost: ¥34,100,000、Indirect Cost: ¥10,230,000)
Fiscal Year 2020: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2019: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2018: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2017: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2016: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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Outline of Final Research Achievements |
In this study, we established an analytical platform to perform global ubiquitination and acetylation proteome analyses of human cancer cells using high-resolution nanoflow liquid chromatography-tandem mass spectrometry (nanoLC-MS/MS) system. We also developed a bioinformatical platform named 'Post Translational Modification mapper (PTMapper)' to reconstruct regulatory protein-protein interaction relations at the protein modification level towards systematic network analysis based on PTM-oriented quantitative activation data,
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