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Development and application of next generation metabolome analysis technologies

Planned Research

Project AreaTransomic Analysis of Metabolic Adaptation
Project/Area Number 17H06304
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionKyushu University

Principal Investigator

Takeshi Bamba  九州大学, 生体防御医学研究所, 教授 (10432444)

Co-Investigator(Kenkyū-buntansha) 山田 健一  九州大学, 薬学研究院, 教授 (60346806)
和泉 自泰  九州大学, 生体防御医学研究所, 准教授 (70622166)
相馬 悠希  九州大学, 生体防御医学研究所, 助教 (80781955)
Project Period (FY) 2017-06-30 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥162,240,000 (Direct Cost: ¥124,800,000、Indirect Cost: ¥37,440,000)
Fiscal Year 2021: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2020: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2019: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2018: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2017: ¥98,280,000 (Direct Cost: ¥75,600,000、Indirect Cost: ¥22,680,000)
Keywordsメタボローム解析 / メタボロミクス / トランスオミクス / 代謝アダプテーション
Outline of Final Research Achievements

We have been working on the development of next-generation metabolome analysis base technologies that enables quantitative metabolome analysis and contributes to metabolic adaptation analysis. We succeeded in developing a quantitative metabolome analysis system using various chromatography-mass spectrometry systems. We also developed a system for quantitative analysis of individual components by combining LC and various detectors. In addition, we developed stable isotope-labeled internal standards necessary for quantitative analysis in mass spectrometry, probes for highly sensitive quantitative analysis of trace components, and a data analysis system for quantitative metabolome analysis. We have established the basic technologies for quantitative metabolome analysis, and have conducted many applied studies of metabolic adaptation using these technologies with collaborators both inside and outside of the project.

Academic Significance and Societal Importance of the Research Achievements

本研究により定量メタボロームデータを取得することが可能になったことで,これまで困難であった詳細な代謝解析や他のオミクスとの統合解析が実施できるようになった.また,コフォート研究など継続的にメタボロームデータを蓄積し解析する場合においても,分析バッチの異なる過去のデータとの比較,統合解析が可能になった.本研究における成果は,学術分野だけでなく様々な産業においても波及効果を与えるものと思われる.今後,本研究において開発されたメタボローム解析技術によりメタボロミクスがさらなる発展をとげ,新しい代謝解析の世界を拓くことが期待される.

Report

(6 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (185 results)

All 2022 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (2 results) Journal Article (40 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 40 results,  Open Access: 22 results) Presentation (128 results) (of which Int'l Joint Research: 36 results,  Invited: 72 results) Book (8 results) Patent(Industrial Property Rights) (7 results) (of which Overseas: 1 results)

  • [Int'l Joint Research] University of Orleans(フランス)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] National Institutes of Health/Thermo Fisher Scientific/Shimadzu Scientific Instruments(米国)

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Quantitative metabolomics for dynamic metabolic engineering using stable isotope labeled internal standards mixture (SILIS).2022

    • Author(s)
      Soma Y#, Takahashi M#, Fujiwara Y, Tomiyasu N, Goto M, Hanai T, Izumi Y, Bamba T*.
    • Journal Title

      J. Biosci. Bioeng.

      Volume: 133(1) Issue: 1 Pages: 46-55

    • DOI

      10.1016/j.jbiosc.2021.09.009

    • NAID

      40022801277

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dynamic metabolic engineering of Escherichia coli improves fermentation for the production of pyruvate and its derivatives2022

    • Author(s)
      Soma Yuki、Yamaji Taiki、Hanai Taizo
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: 133 Issue: 1 Pages: 56-63

    • DOI

      10.1016/j.jbiosc.2021.09.015

    • NAID

      40022801279

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Targeting leukemia-specific dependence on the de novo purine synthesis pathway.2022

    • Author(s)
      Yamauchi T, Miyawaki K, Semba Y, Takahashi M, Izumi Y, Nogami J, Nakao F, Sugio T, Sasaki K, Pinello L, Bauer DE, Bamba T, Akashi K, Maeda T*.
    • Journal Title

      Leukemia

      Volume: 36(2) Issue: 2 Pages: 383-393

    • DOI

      10.1038/s41375-021-01369-0

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Comparative Evaluation of Plasma Metabolomic Data from Multiple Laboratories2022

    • Author(s)
      Nishiumi S#*, Izumi Y#*, Hirayama A#*, Takahashi M, Nakao M, Hata K, Saigusa D, Hishinuma E, Matsukawa N, M Tokuoka S, Kita Y, Hamano F, Okahashi N, Ikeda K, Nakanishi H, Saito K, Yokota Hirai M, Yoshida M, Oda Y, Matsuda F, Bamba T.
    • Journal Title

      Metabolites

      Volume: 12 Issue: 2 Pages: 135-135

    • DOI

      10.3390/metabo12020135

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.2022

    • Author(s)
      Mise S#, Matsumoto A#*, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, Nakayama KI*.
    • Journal Title

      Nat. Commun.

      Volume: 13(1) Issue: 1 Pages: 1071-1071

    • DOI

      10.1038/s41467-022-28677-y

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Differential effect of canagliflozin, a sodium-glucose cotransporter (SGLT2) inhibitor, on slow and fast skeletal muscles from nondiabetic mice.2022

    • Author(s)
      Otsuka H, Yokomizo H*, Nakamura S, Izumi Y, Takahashi M, Obara S, Nakao M, Ikeda Y, Sato N, Sakamoto R, Miyachi Y, Miyazawa T, Bamba T, Ogawa Y*.
    • Journal Title

      Biochem. J.

      Volume: 479(3) Issue: 3 Pages: 425-444

    • DOI

      10.1042/bcj20210700

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Investigation of supercritical fluid chromatography retention behaviors using quantitative structure-retention relationships.2022

    • Author(s)
      Si-Hung L, Izumi Y, Nakao M, Takahashi M, Bamba T*.
    • Journal Title

      Anal. Chim. Acta

      Volume: 1197 Pages: 339463-339463

    • DOI

      10.1016/j.aca.2022.339463

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells2022

    • Author(s)
      Tatsuguchi T., Uruno T., Sugiura Y., Sakata D., Izumi Y., Sakurai T., Hattori Y., Oki E., Kubota N., Nishimoto K., Oyama M., Kunimura K., Ohki T., Bamba T., Tahara H., Sakamoto M., Nakamura M., Suematsu M., Fukui Y.
    • Journal Title

      Int. Immunol.

      Volume: - Issue: 5 Pages: 277-289

    • DOI

      10.1093/intimm/dxac002

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Design of synthetic quorum sensing achieving induction timing-independent signal stabilization for dynamic metabolic engineering of E. coli.2021

    • Author(s)
      Soma Y, Takahashi M, Fujiwara Y, Shinohara T, Izumi Y, Hanai T*, Bamba T*.
    • Journal Title

      ACS Synth. Biol.

      Volume: 10(6) Issue: 6 Pages: 1384-1393

    • DOI

      10.1021/acssynbio.1c00008

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Skeletal muscle-specific Keap1 disruption modulates fatty acid utilization and enhances exercise capacity in female mice.2021

    • Author(s)
      Onoki T, Izumi Y, Takahashi M, Murakami S, Matsumaru D, Ohta N, Wati SM, Hatanaka N, Katsuoka F, Okutsu M, Yabe Y, Hagiwara Y, Kanzaki M, Bamba T, Itoi E, Motohashi H*.
    • Journal Title

      Redox Biol.

      Volume: 43 Pages: 101966-101966

    • DOI

      10.1016/j.redox.2021.101966

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Performance of functionalized monolithic silica capillary columns with different mesopore sizes using radical polymerization of octadecyl methacrylate.2021

    • Author(s)
      Hara T, Baron G V, Hata K, Izumi Y, Bamba T*, Desmet G*
    • Journal Title

      J. Chromatogr. A

      Volume: 1651 Pages: 462282-462282

    • DOI

      10.1016/j.chroma.2021.462282

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Interlaboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities: evaluation of multi-systems reproducibility2021

    • Author(s)
      Dispas A., et al.
    • Journal Title

      J. Pharm. Biomed. Anal.

      Volume: 203 Pages: 114206-114206

    • DOI

      10.1016/j.jpba.2021.114206

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Produced β-hydroxybutyrate after β-hydroxy-β-methylbutyrate (HMB) administration may contribute HMB function in mice.2021

    • Author(s)
      Ikeda K#, Takahashi M#, Aburaya S, Harada D, Ikeda M, Kitagawa Y, Soma Y, Izumi Y, Bamba T, Furuse M*.
    • Journal Title

      Biochem. Biophys. Rep.

      Volume: 27 Pages: 101097-101097

    • DOI

      10.1016/j.bbrep.2021.101097

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Porphyromonas gingivalis induces entero-hepatic metabolic derangements with alteration of gut microbiota in a type 2 diabetes mouse model.2021

    • Author(s)
      Kashiwagi Y#, Aburaya S#, Sugiyama N#, Narukawa Y, Sakamoto Y, Takahashi M, Uemura H, Yamashita R, Tominaga S, Hayashi S, Nozaki T, Yamada S, Izumi Y, Kashiwagi A, Bamba T, Ishihama Y, Murakami S*.
    • Journal Title

      Sci. Rep.

      Volume: 11(1) Issue: 1 Pages: 18398-18398

    • DOI

      10.1038/s41598-021-97868-2

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of kit-based metabolomics with other methodologies in a large cohort, towards establishing reference values2021

    • Author(s)
      Saigusa D*, Hishinuma E, Matsukawa N, Takahashi M, Inoue J, Tadaka S, Motoike I N, Hozawa A, Izumi Y, Bamba T, Kinoshita K, Ekroos K, Koshiba S, Yamamoto M.
    • Journal Title

      Metabolites

      Volume: 11 Issue: 10 Pages: 652-652

    • DOI

      10.3390/metabo11100652

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques.2021

    • Author(s)
      Matsuoka Y, Takahashi M, Sugiura Y, Izumi Y, Nishiyama K, Nishida M, Suematsu M, Bamba T, Yamada KI*.
    • Journal Title

      Nat. Commun.

      Volume: 12(1) Issue: 1 Pages: 6339-6339

    • DOI

      10.1038/s41467-021-26633-w

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of Change in Metabolome Caused by Comprehensive Diabetes Treatment: A Prospective Observational Study of Diabetes Inpatients with GC/MS-Based Non-Target Metabolomic Analysis2021

    • Author(s)
      Taya N., Katakami N., Omori K., Arakawa S., Watanabe H., Hosoe S., Miyashita K., Takahara M., Nishizawa H., Matsuoka T.A., Furuno M., Bamba T., Iida J., Fukusaki E., Shimomura I.
    • Journal Title

      J. Diabetes Investig.

      Volume: 12(12) Issue: 12 Pages: 2232-2241

    • DOI

      10.1111/jdi.13600

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Enzyme systems involved in glucosinolate metabolism in Companilactobacillus farciminis KB1089.2021

    • Author(s)
      Watanabe H#, Usami R#, Kishino S#, Osada K, Aoki Y, Morisaka H, Takahashi M, Izumi Y, Bamba T, Aoki W, Suganuma H, Ogawa J*.
    • Journal Title

      Sci. Rep.

      Volume: 11(1) Issue: 1 Pages: 23715-23715

    • DOI

      10.1038/s41598-021-03064-7

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Detection and structural analysis of pyrimidine-derived radicals generated on DNA using a profluorescent nitroxide probe.2021

    • Author(s)
      Yamauchi K, Matsuoka Y, Takahashi M, Izumi Y, Taniguchi Y, Kawai K, Bamba T, Yamada KI*.
    • Journal Title

      Chem. Commun.

      Volume: 58(1) Issue: 1 Pages: 56-59

    • DOI

      10.1039/d1cc04998d

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Calibration-curve-locking database for semi-quantitative metabolomics by gas chromatography/mass spectrometry.2021

    • Author(s)
      Hata K#, Soma Y#, Yamashita T, Takahashi M, Sugitate K, Serino T, Miyagawa H, Suzuki K, Yamada K, Kawamukai T, Shiota T, Izumi Y*, Bamba T*.
    • Journal Title

      Metabolites

      Volume: 11(4) Issue: 4 Pages: 207-207

    • DOI

      10.3390/metabo11040207

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An Analytical System for Single-Cell Metabolomics of Typical Mammalian Cells Based on Highly Sensitive Nano-Liquid Chromatography Tandem Mass Spectrometry2020

    • Author(s)
      Nakatani K, Izumi Y*, Hata K, Bamba T.
    • Journal Title

      Mass Spectrometry

      Volume: 9 Issue: 1 Pages: A0080-A0080

    • DOI

      10.5702/massspectrometry.A0080

    • NAID

      130007809373

    • ISSN
      2186-5116, 2187-137X
    • Year and Date
      2020-03-17
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Method for Structural Determination of Lipid-Derived Radicals2020

    • Author(s)
      Matsuoka Yuta、Izumi Yoshihiro、Takahashi Masatomo、Bamba Takeshi、Yamada Ken-ichi
    • Journal Title

      Analytical Chemistry

      Volume: - Issue: 10 Pages: 6993-7002

    • DOI

      10.1021/acs.analchem.0c00053

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel comprehensive analytical method for volatile compounds using supercritical fluid chromatography/mass spectrometry with a highly cross-linked styrene divinylbenzene polymer-based column2020

    • Author(s)
      Fujito, Y., Hayakawa, Y., Bamba, T.
    • Journal Title

      J. Chromatogr. A

      Volume: 1626 Pages: 461363-461363

    • DOI

      10.1016/j.chroma.2020.461363

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel method for polar metabolite profiling by supercritical fluid chromatography/tandem mass spectrometry.2020

    • Author(s)
      Konya Y, Izumi Y, Bamba T*.
    • Journal Title

      J. Chromatogr. A

      Volume: 1632 Pages: 461587-461587

    • DOI

      10.1016/j.chroma.2020.461587

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic metabolome analysis reveals the metabolic fate of medium-chain fatty acid in AML12 cells.2020

    • Author(s)
      Fushimi T, Izumi Y*, Takahashi M, Hata K, Murano Y, Bamba T.
    • Journal Title

      J. Agric. Food Chem.

      Volume: 68(43) Issue: 43 Pages: 11997-12010

    • DOI

      10.1021/acs.jafc.0c04723

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.2020

    • Author(s)
      Matsuda J, Takahashi A, Takabatake Y*, Sakai S, Minami S, Yamamoto T, Fujimura R, Namba-Hamano T, Yonishi H, Nakamura J, Kimura T, Kaimori J, Matsui I, Takahashi M, Nakao M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Yanagita M, Yoshimori T, Isaka Y.
    • Journal Title

      Autophagy

      Volume: 16 Issue: 10 Pages: 1-16

    • DOI

      10.1080/15548627.2020.1712107

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lipidomic analysis of cells and extracellular vesicles from high- and low-metastatic triple-negative breast cancer.2020

    • Author(s)
      Nishida-Aoki N, Izumi Y*, Takeda H, Takahashi M, Ochiya T*, Bamba T.
    • Journal Title

      Metabolites

      Volume: 10(2) Issue: 2 Pages: 67-67

    • DOI

      10.3390/metabo10020067

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Lipid profiling of serum and lipoprotein fractions in response to pitavastatin using an animal model of familial hypercholesterolemia.2020

    • Author(s)
      Takeda H, Izumi Y*, Tamura S, Koike T, Koike Y, Shiomi M, Bamba T.
    • Journal Title

      J. Proteome Res.

      Volume: 19(3) Issue: 3 Pages: 1100-1108

    • DOI

      10.1021/acs.jproteome.9b00602

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A shift in glutamine nitrogen metabolism contributes to malignant progression of cancer.2020

    • Author(s)
      Kodama M, Oshikawa K, Shimizu H, Yoshioka S, Takahashi M, Izumi Y, Bamba T, Tateishi C, Tomonaga T, Matsumoto M*, Nakayama KI*.
    • Journal Title

      Nat. Commun.

      Volume: 11 Issue: 1 Pages: 1320-1320

    • DOI

      10.1038/s41467-020-15136-9

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Performance of small-domain monolithic silica columns in nano-liquid chromatography and comparison with commercial packed bed columns with 2 μm particles.2020

    • Author(s)
      Hara T, Izumi Y, Hata K, Baron G V, Bamba T, Desmet G*
    • Journal Title

      J. Chromatogr. A

      Volume: 1616 Pages: 460804-460804

    • DOI

      10.1016/j.chroma.2019.460804

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Identification of Plasma Inositol and Indoxyl Sulfate as Novel Biomarker Candidates for Atherosclerosis in Patients with Type 2 Diabetes. -Findings from Metabolome Analysis Using GC/MS2020

    • Author(s)
      Omori, K., Katakami, N., Arakawa, S., Yamamoto, Y., Ninomiya, H., Takahara, M., Matsuoka, TA., Tsugawa, H., Furuno, M., Bamba, T., Fukusaki, E., Shimomura, I.
    • Journal Title

      J. Atheroscler. Thromb.

      Volume: -

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of retention behavior between supercritical fluid chromatography and normal-phase high performance liquid chromatography with various stationary phases.2019

    • Author(s)
      Hirose T*, Keck D, Izumi Y, Bamba T.
    • Journal Title

      Molecules

      Volume: 24(13) Issue: 13 Pages: 2425-2425

    • DOI

      10.3390/molecules24132425

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improved quantitation of lipid classes using supercritical fluid chromatography with charged aerosol detector.2019

    • Author(s)
      Takeda H, Takahashi M, Hara T, Izumi Y, Bamba T*
    • Journal Title

      J. Lipid Res.

      Volume: 60(8) Issue: 8 Pages: 1465-1474

    • DOI

      10.1194/jlr.d094516

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inter-laboratory comparison of metabolite measurements for metabolomics data integration2019

    • Author(s)
      Izumi Yoshihiro、Matsuda Fumio、Hirayama Akiyoshi、Ikeda Kazutaka、Kita Yoshihiro、Horie Kanta、Saigusa Daisuke、Saito Kosuke、Sawada Yuji、Nakanishi Hiroki、Okahashi Nobuyuki、Takahashi Masatomo、Nakao Motonao、Hata Kosuke、Hoshi Yutaro、Morihara Motohiko、Tanabe Kazuhiro、Bamba Takeshi、Oda Yoshiya
    • Journal Title

      Metabolites

      Volume: 9 Issue: 11 Pages: 257-257

    • DOI

      10.3390/metabo9110257

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of a practical online supercritical fluid extraction-supercritical fluid chromatography/mass spectrometry system with an integrated split-flow method2019

    • Author(s)
      Sakai, M., Hayakawa, Y., Funada, Y., Ando, T., Fukusaki, E., Bamba, T.
    • Journal Title

      J. Chromatogra. A

      Volume: 1592 Pages: 161-172

    • DOI

      10.1016/j.chroma.2019.01.044

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of sequential derivatization with concurrent methods for GC/MS-based metabolomics2019

    • Author(s)
      Miyagawa, H., Bamba, T.
    • Journal Title

      J. Biosci. Bioeng.

      Volume: 127 Issue: 2 Pages: 160-168

    • DOI

      10.1016/j.jbiosc.2018.07.015

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Highly Accurate Detection and Identification Methodology of Xenobiotic Metabolites Using Stable Isotope Labeling, Data Mining Techniques, and Time-Dependent Profiling Based on LC/HRMS/MS2018

    • Author(s)
      Takahashi, M., Izumi, Y., Iwahashi, F., Nakayama, Y., Iwakoshi, M., Nakao, M., Yamato, S., Fukusaki, E., Bamba, T.
    • Journal Title

      Anal. Chem.

      Volume: 90(15) Issue: 15 Pages: 9068-9076

    • DOI

      10.1021/acs.analchem.8b01388

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Widely-targeted quantitative lipidomics method by supercritical fluid chromatography triple quadrupole mass spectrometry2018

    • Author(s)
      Takeda, H., Izumi, Y., Takahashi, M., Paxton, T., Tamura, S., Koike, T., Yu, Y., Kato, N., Nagase, K., Shiomi, M., Bamba, T.
    • Journal Title

      J. Lipid Res.

      Volume: 59 (7) Issue: 7 Pages: 1283-1293

    • DOI

      10.1194/jlr.d083014

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Harmonizing Lipidomics: NIST Interlaboratory Comparison Exercise for Lipidomics using Standard Reference Material 1950-Metabolites in Frozen Human Plasma.2017

    • Author(s)
      Bowde J A, Heckert A, Ulmer C Z, Jones C M, Koelmel J P, Izumi Y et a.
    • Journal Title

      J. Lipid Res.

      Volume: 58(12) Issue: 12 Pages: 2275-2288

    • DOI

      10.1194/jlr.m079012

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Solid-phase analytical derivatization for gas-chromatography-mass-spectrometry-based metabolomics2017

    • Author(s)
      Takeo, E., Sasano, R., Shimma, S., Bamba, T., Fukusaki, E.
    • Journal Title

      J. Biosci. Bioeng.

      Volume: 124 (6) Issue: 6 Pages: 700-706

    • DOI

      10.1016/j.jbiosc.2017.07.006

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] An analytical system for comprehensive quantitative profiling of bioactive lipids by solid phase extraction combined with LC/MS/MS2022

    • Author(s)
      Kohta Nakatani, Yoshihiro Izumi, Hironobu Umakoshi, Ayako Hidaka, Masatoshi Ogata, Yoshihiro Ogawa, Takeshi Bamba
    • Organizer
      The 30th Hot Spring Harbor International Symposium
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 新たな定量リピドーム分析システムの開発2022

    • Author(s)
      馬場 健史
    • Organizer
      株式会社久留米リサーチ・パークリピドミクスセミナー
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 持続的NFκB活性による細胞老化関連代謝変化2022

    • Author(s)
      田畑 祥,和泉 自泰,高橋 政友,馬場 健史,岡田 眞里子
    • Organizer
      第95回 日本薬理学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 代謝特性の異なる遅筋と速筋に着目したSGLT2阻害薬の骨格筋代謝調節作用の解明2022

    • Author(s)
      横溝 久,大塚 裕子,中村 慎太郎,園田 紀之,宮澤 崇,和泉 自泰,高橋 政友,馬場 健史,小川 佳宏
    • Organizer
      第42回 日本肥満学会・第39回 日本肥満症治療学会学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] メタボロミクス技術の最新動向と今後の課題2021

    • Author(s)
      馬場 健史
    • Organizer
      新化学技術推進協会 ライフサイエンス技術部会 反応分科会 勉強会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 高感度nano-uHILIC/AEX/MS/MSによる少数細胞集団試料のメタボローム分析2021

    • Author(s)
      中谷 航太,和泉 自泰,秦 康祐,高橋 政友,内田 穣,石井 優,馬場 健史
    • Organizer
      第69回 質量分析総合討論会
    • Related Report
      2021 Annual Research Report
  • [Presentation] LC/MSを基盤とした血漿メタボローム分析法の性能評価2021

    • Author(s)
      今戸 優理,油屋 駿介,高橋 政友,中谷 航太,相馬 悠希,和泉 自泰,馬場 健史
    • Organizer
      第69回 質量分析総合討論会
    • Related Report
      2021 Annual Research Report
  • [Presentation] メタボロームデータ取得の現状と課題2021

    • Author(s)
      馬場 健史
    • Organizer
      第3回 国際活性硫黄研究会
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 質量分析を基盤とした1細胞分子フェノタイピング技術の開発2021

    • Author(s)
      馬場 健史
    • Organizer
      第28回 HAB研究機構学術年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 定量メタボロームデータ取得に向けた分析技術およびソフトウエア開発2021

    • Author(s)
      馬場 健史,中尾 素直
    • Organizer
      質量分析インフォマティクス研究会 第6回 ワークショップ
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] ナノ液体クロマトグラフィー質量分析を基盤としたシングルセル分子フェノタイプ解析2021

    • Author(s)
      和泉 自泰,馬場 健史
    • Organizer
      代謝統合オミクス 第2回 新学術計測セミナー
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Development of a widely-targeted quantitative lipidomics methodology by supercritical fluid chromatography coupled with triple quadrupole mass spectrometry2021

    • Author(s)
      Hiroaki Takeda, Yoshihiro Izumi, Masatomo Takahashi, Motonao Nakao, Takeshi Bamba
    • Organizer
      Metabolomics 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] LC/MSを基盤とした血漿メタボローム分析法の性能評価2021

    • Author(s)
      今戸 優理,油屋 駿介,高橋 政友,中谷 航太,相馬 悠希,和泉 自泰,馬場 健史
    • Organizer
      生物工学若手研究者の集い 夏のオンラインセミナー 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] β-ヒドロキシ-β-メチルブチレート (HMB) の機能解明に関する研究:ケトン体産生能の関与2021

    • Author(s)
      池田 和輝,高橋 政友,油屋 駿介,原田 大暉,池田 麻貴,北川 優芽,相馬 悠希,和泉 自泰,馬場 健史,古瀬 充宏
    • Organizer
      生物工学若手研究者の集い 夏のオンラインセミナー 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] Remote solid cancers rewire hepatic nitrogen metabolism via host nicotinamide-N- methyltransferase2021

    • Author(s)
      Rin Mizuno, Hiroaki Hojo, Masatomo Takahashi, Soshiro Kashio, Sora Enya, Motonao Nakao, Riyo Konishi, Junzo Hamanishi, Hiroshi Kawamoto, Masaki Mandai, Yutaka Suzuki, Masayuki Miura, Takeshi Bamba, Yoshihiro Izumi, Shinpei Kawaoka
    • Organizer
      6th Cancer Cachexia Conference
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 超臨界流体クロマトグラフィー/タンデム質量分析法を用いた非誘導体化アミノ酸鏡像体の超高速同時キラル分析2021

    • Author(s)
      紺屋 豊,和泉 自泰,馬場 健史
    • Organizer
      第16回 D-アミノ酸学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 超臨界流体クロマトグラフィータンデム質量分析による新規ワイドターゲットリピドーム分析システムの開発2021

    • Author(s)
      馬場 健史
    • Organizer
      第46回 日本医用マススペクトル学会年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 気相微生物反応における Methylococcus capsulatus str. Bath の代謝動態の変化2021

    • Author(s)
      石川 聖人,Chen Yan-yu,相馬 悠希,高橋 政友,和泉 自泰,馬場 健史,堀 克敏
    • Organizer
      化学工学会 第52回 秋季大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] メタボロミクスのコツ2021

    • Author(s)
      馬場 健史
    • Organizer
      第15回 メタボロームシンポジウム
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Vitamin B6 is an Oxygen-Sensitive Nutrient Shaping Macrophage Inflammatory Phenotype under Chronic Hypoxia by Suppressing Lysosomal Activity2021

    • Author(s)
      Hiroki Sekine, Akihiro Kishino, Hayato Anzawa, Yoshihiro Izumi, Masatomo Takahashi, Takeshi Bamba, Kengo Kinoshita, Hozumi Motohashi
    • Organizer
      Cold Spring Harbor Laboratory meeting
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Retention time model for chromatographic interactions investigation using supercritical fluid chromatography coupled to mass spectrometry2021

    • Author(s)
      Hung Si Le, Yoshihiro Izumi, Motonao Nakao, Masatomo Takahashi, Takeshi Bamba
    • Organizer
      69th ASMS Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ultrafast simultaneous chiral analysis of native amino acid enantiomers using supercritical fluid chromatography/tandem mass spectrometry2021

    • Author(s)
      Yutaka Konya, Yoshihiro Izumi, Takeshi Bamba
    • Organizer
      69th ASMS Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ナノ液体クロマトグラフィー質量分析を基盤としたシングルセル分子フェノタイプ解析法の開発2021

    • Author(s)
      和泉 自泰,秦 康祐,中谷 航太,山村 昌平,松本 雅記,馬場 健史
    • Organizer
      第94回 日本生化学会大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Liquid biopsyにおけるメタボローム分析技術の可能性2021

    • Author(s)
      馬場 健史
    • Organizer
      第61回 日本臨床化学会年次学術集会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Newly developed mass spectrometry-based analytical system for single-cell metabolomics and proteomics2021

    • Author(s)
      Yoshihiro Izumi, Kosuke Hata, Kohta Nakatani, Shohei Yamamura, Masaki Matsumoto, Takeshi Bamba
    • Organizer
      The 26th Symposium of Young Asian Biological Engineers’ Community
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Challenge to single-cell metabolome and proteome analyses2021

    • Author(s)
      Yoshihiro Izumi, Kohta Nakatani, Kosuke Hata, Shohei Yamamura, Masaki Matsumoto, Takeshi Bamba
    • Organizer
      第59回 日本生物物理学会年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 呼吸鎖阻害に対するがん細胞と出芽酵母の代謝アダプテーション解析2021

    • Author(s)
      澤井 茜,清家 泰介,岡橋 伸幸,和泉 自泰,馬場 健史,松田 史生
    • Organizer
      第44回 日本分子生物学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 持続的NFκBの持続的な活性化による細胞老化の誘導2021

    • Author(s)
      田畑 祥,溝口 亜紀美,Miguel Luis A. Francisco,高橋 政友,和泉 自泰,馬場 健史,岡田 眞里子
    • Organizer
      第44回 日本分子生物学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] エクソソームの定量リピドーム解析2021

    • Author(s)
      和泉 自泰,西田 奈央,竹田 浩章,高橋 政友,落谷 孝広,馬場 健史
    • Organizer
      第3回 脂質駆動学術産業創生研究部会講演会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] メタボロミクスを活用した肝細胞における中鎖脂肪酸代謝物解析2021

    • Author(s)
      伏見 達也,和泉 自泰,高橋 政友,秦 康祐,村野 賢博,馬場 健史
    • Organizer
      第3回 脂質駆動学術産業創生研究部会講演会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Development of metabolic profiling methodologies based on supercritical fluid extraction and separation technologies2021

    • Author(s)
      Takeshi Bamba
    • Organizer
      Pacifichem 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of wide-targeted lipidomics system by using SFC-triple quadrupole MS2021

    • Author(s)
      Takeshi Bamba
    • Organizer
      9th International Singapore Lipid Symposium (iSLS 9)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ワイドターゲット定量リピドーム分析システムを用いた馬場メソッド~リピドーム分析の課題を解決!~2021

    • Author(s)
      馬場健史
    • Organizer
      Waters Webinar
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] メタボロミクスを実施する上での重要ポイント2021

    • Author(s)
      馬場健史
    • Organizer
      日本農芸化学会 2021年度大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 親水性代謝物のワイドターゲットメタボローム分析のプロトコル2021

    • Author(s)
      和泉自泰
    • Organizer
      日本農芸化学会 2021年度大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 超臨界流体クロマトグラフィーって何ができるの?2020

    • Author(s)
      馬場健史
    • Organizer
      島津Webinar
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 次世代超臨界流体抽出分離装置の開発2020

    • Author(s)
      馬場健史
    • Organizer
      日本農芸化学会 2020年度 中四国支部大会(第57回 講演会)産学連携シンポジウム
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] メタボロームデータ取得方法の現状と課題2020

    • Author(s)
      馬場健史
    • Organizer
      ゲノム創薬・創発フォーラム 第四回 シンポジウム
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] メタボローム分析の最新動向と今後の課題2020

    • Author(s)
      馬場健史
    • Organizer
      第31回 クロマトグラフィー科学会議
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] メタボロミクスの最新動向2020

    • Author(s)
      馬場健史
    • Organizer
      プラズマバイオコンソーシアム 2020年度研究会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] オートサンプラーのニードル内混合機能を活用したアミノ酸の自動蛍光誘導体化分析法の開発2020

    • Author(s)
      下平武彦,相馬悠希,品玉匠司,大城真愛,早川禎宏,和泉自泰,馬場健史
    • Organizer
      2020年度 日本フードファクター学会・日本農芸化学会西日本支部合同大会(第332回 講演会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 定量メタボローム解析の事業化に向けた取り組み2020

    • Author(s)
      馬場健史
    • Organizer
      2020年度 第5回 九州大学ベンチャーエコシステム連絡会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Development of polar metabolite profiling method by supercritical fluid chromatography/mass spectrometry2020

    • Author(s)
      Yutaka Konya, Yoshihiro Izumi, Takeshi Bamba
    • Organizer
      AOMSC 2020
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Single-run comprehensive hydrophilic metabolome analysis by unified hydrophilic-interaction/anion-exchange liquid chromatography mass spectrometry2020

    • Author(s)
      Kohta Nakatani, Yoshihiro Izumi, Masatomo Takahashi, Keita Sakurai, Michio Butsugan, Takeshi Bamba
    • Organizer
      AOMSC 2020
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] SFCの未来2020

    • Author(s)
      馬場健史
    • Organizer
      Nexera UC Prep発売記念セミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] SFCによる揮発性成分の分析2020

    • Author(s)
      藤戸由佳, 早川禎宏, 馬場健史
    • Organizer
      第5回 食品SFC懇談会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] SFCによる揮発性成分の分析2020

    • Author(s)
      藤戸由佳, 早川禎宏, 馬場健史
    • Organizer
      第20回 SFC研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Development of single-cell molecular phenotyping technologies based on mass spectrometry2020

    • Author(s)
      Takeshi Bamba
    • Organizer
      The 29th Hot Spring Harbor International Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 脂質由来ラジカル種の構造解析法2019

    • Author(s)
      松岡悠太, 和泉自泰, 高橋政友, 馬場健史, 山田健一
    • Organizer
      第67回 質量分析総合討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 新規スプリットフロー法を用いた実用SFE-SFC/MSシステムの開発2019

    • Author(s)
      酒井美穂, 早川禎宏, 舟田康裕, 安藤孝, 福崎英一郞, 馬場健史
    • Organizer
      第67回 質量分析総合討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 超臨界流体クロマトグラフィー三連四重極型質量分析によるワイドターゲット定量リピドーム分析法の開発2019

    • Author(s)
      高橋政友, 竹田浩章, 和泉自泰, 馬場健史
    • Organizer
      第67回 質量分析総合討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 親水性相互作用/陰イオン交換クロマトグラフィータンデム質量分析による次世代メタボローム分析法の開発2019

    • Author(s)
      中谷航太, 和泉自泰, 高橋政友, 櫻井恵太, 佛願道男, 馬場健史
    • Organizer
      第67回 質量分析総合討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Metabolic profiling by supercritical fluid extraction and separation2019

    • Author(s)
      Takeshi Bamba
    • Organizer
      SFC/SFE China 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Highly Accurate Detection and Identification Methodology of Xenobiotic Metabolites Using Stable Isotope Labeling, LC/HRMS/MS Analysis, and Data Mining Techniques2019

    • Author(s)
      Masatomo Takahashi, Yoshihiro Izumi, Fukumatsu Iwahashi, Yasumune Nakayama, Mitsuhiko Iwakoshi, Motonoa Nakao, Seiji Yamato, Eiichiro Fukusaki, Takeshi Bamba
    • Organizer
      67th ASMS Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Liquid-Chromatography coupled to Tandem Mass Spectrometry for 28 Bile Acids Profiling in Serum or Liver Samples2019

    • Author(s)
      Yoshihiro Izumi, Mikael Levi, Jun Watanabe, Takeshi Bamba
    • Organizer
      67th ASMS Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A Novel Mass Spectrometry-Based Analytical System for Single-Cell Proteomics and Metabolomics in Mammalian Cells2019

    • Author(s)
      Yoshihiro Izumi, Kousuke Hata, Kohta Nakatani, Takeshi Hara, Shohei Yamamura, Masaki Matsumoto, Takeshi Bamba
    • Organizer
      67th ASMS Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Large-Scale Metabolomic Analysis of Hydrophilic Metabolites Using Hydrophilic Interaction Liquid Chromatography Tandem Mass Spectrometry with a Novel Polymer-Based Amino Column2019

    • Author(s)
      Kohta Nakatani, Yoshihiro Izumi, Masatomo Takahashi, Keita Sakurai, Michio Butsugan, Takeshi Bamba
    • Organizer
      67th ASMS Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Lipidomic analysis for the prediction of cholesterol efflux capacity and atherosclerotic cardiovascular disease2019

    • Author(s)
      Masatsune Ogura, Hiroaki Takeda, Yoshihiro Izumi, Mika Hori, Kota Matsuki, Masashi Yamamoto, Takeshi Bamba, Mariko Harada-Shiba
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Novel analytical method for global metabolomic analysis by hydrophilic interaction/anion-exchange liquid chromatography tandem mass spectrometry2019

    • Author(s)
      Kohta Nakatani, Yoshihiro Izumi, Masatomo Takahashi, Keita Sakurai, Michio Butsugan, Takeshi Bamba
    • Organizer
      15th Annual Conference of the Metabolomics Society (Metabolomics 2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] シングルセル分子フェノタイプ解析に向けた基盤技術の創生2019

    • Author(s)
      和泉自泰, 松本雅記, 山村昌平, 馬場健史
    • Organizer
      日本プロテオーム学会2019年大会 第70回日本電気泳動学会総会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 次世代メタボローム分析法:親水性相互作用/陰イオン交換クロマトグラフィータンデム質量分析の開発2019

    • Author(s)
      中谷航太, 和泉自泰, 高橋政友, 櫻井恵太, 佛願道男, 馬場健史
    • Organizer
      日本プロテオーム学会2019年大会 第70回日本電気泳動学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 1細胞マルチ分子フェノタイピング技術の開発2019

    • Author(s)
      馬場健史, 和泉自泰
    • Organizer
      京都バイオ計測センター・京都大学ナノハブ拠点連携シンポジウム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 超臨界流体クロマトグラフィーの基礎2019

    • Author(s)
      馬場健史
    • Organizer
      第19回 SFC研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Basic Understanding SFC and SFE2019

    • Author(s)
      Takeshi Bamba
    • Organizer
      Food Analysis Workshop 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of metabolomics technologies by using SFC and SFE2019

    • Author(s)
      Takeshi Bamba
    • Organizer
      Food Analysis Workshop 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 超臨界流体の利用によって広がる新たな分離分析技術の可能性2019

    • Author(s)
      馬場健史
    • Organizer
      JASIS 2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] 質量分析を基盤としたシングルセル分子フェノタイプ解析2019

    • Author(s)
      和泉自泰, 馬場健史
    • Organizer
      第71回 日本生物工学会大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 親水性相互作用/陰イオン交換クロマトグラフィータンデム質量分析による親水性代謝物の一斉分析法の開発2019

    • Author(s)
      中谷航太, 和泉自泰, 高橋政友, 櫻井恵太, 佛願道男, 馬場健史
    • Organizer
      第71回 日本生物工学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 次世代定量メタボローム解析に資する安定同位体標識内部標準品群調製法の開発2019

    • Author(s)
      相馬悠希, 藤原由梨, 高橋政友, 後藤麻衣子, 下平武彦, 池田明夏里, 寺内勉, 和泉自泰, 馬場健史
    • Organizer
      第71回 日本生物工学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 1細胞分子フェノタイプ解析に向けた基盤技術の創生2019

    • Author(s)
      和泉自泰, 馬場健史
    • Organizer
      Single Cellome Co-Innovators’Consortium 第1回 オープンフォーラム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Development of next generation metabolome analytical technologies for trans-omics2019

    • Author(s)
      Takeshi Bamba
    • Organizer
      The 57th Annual Meeting of the Biophysical Society of Japan
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of polar metabolite profiling method by supercritical fluid chromatography/mass spectrometry2019

    • Author(s)
      Yutaka Konya, Yoshihiro Izumi, Takeshi Bamba
    • Organizer
      SFC 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Unified HILIC/AEX/MS/MSによる新規メタボローム分析法の開発2019

    • Author(s)
      和泉自泰, 中谷航太, 櫻井恵太, 佛願道男, 馬場健史
    • Organizer
      第13回 メタボロームシンポジウム
    • Related Report
      2019 Annual Research Report
  • [Presentation] トランスオミクスに向けた定量メタボローム分析技術の開発2019

    • Author(s)
      馬場健史
    • Organizer
      第180回 東京脂質談話会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 最新の分離分析技術とその有効括用-分析をうまく使いこなすためには-2019

    • Author(s)
      馬場健史
    • Organizer
      株式会社久留米科学機器 新技術説明会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] メタボロミクスの技術2019

    • Author(s)
      馬場健史
    • Organizer
      第44回 質量分析講習会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 超臨界流体を用いた脂質プロファイリング2019

    • Author(s)
      馬場健史
    • Organizer
      第19回 基準油脂分析試験法セミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Development of metabolic profiling methodologies by supercritical fluid technologies2019

    • Author(s)
      Takeshi Bamba
    • Organizer
      Okinawa Analytical Instrument Network Meeting 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Exploring column performance of monolithic silica capillary columns and its application in nano-LC2019

    • Author(s)
      Takeshi Hara, Kosuke Hata, Yoshihiro Izumi, Gino.V. Baron, Takeshi Bamba and Gert Desmet
    • Organizer
      HPLC 2019 Kyoto
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] これからはじめるメタボロミクス~メタボロミクス解析を有効活用するためには2019

    • Author(s)
      馬場健史
    • Organizer
      第42回 日本分子生物学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Development of single-cell molecular phenotyping technologies based on mass spectrometry.2019

    • Author(s)
      Takeshi Bamba
    • Organizer
      第42回 日本分子生物学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Unified HILIC/AEX/MS/MSによる次世代メタボローム分析法の開発2019

    • Author(s)
      和泉自泰, 中谷航太, 高橋政友, 櫻井恵太, 佛願道男, 馬場健史
    • Organizer
      第30回 クロマトグラフィー科学会議
    • Related Report
      2019 Annual Research Report
  • [Presentation] メタボロミクス有効活用のためには2019

    • Author(s)
      馬場 健史
    • Organizer
      第24回 創薬育薬産学官連携セミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 脂質ラジカルの可視化と構造解析技術開発2019

    • Author(s)
      山田 健一
    • Organizer
      第30回ビタミンE研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] メタボローム分析におけるコロナ検出器の活用法2019

    • Author(s)
      和泉 自泰
    • Organizer
      Thermo Fisher SCIENTIFICコロナフォーラム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] トランスオミクスに向けた次世代メタボローム分析技術の開発2019

    • Author(s)
      馬場 健史
    • Organizer
      第143回 臨床化学セミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] メタボローム分析の最新動向と今後の課題2019

    • Author(s)
      馬場 健史
    • Organizer
      第10回 JBFシンポジウム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Development of next generation metabolome analysis technologies2019

    • Author(s)
      Takeshi Bamba
    • Organizer
      OIST seminar
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 代謝プロファイリングにおける超臨界流体クロマトグラフィーの可能性2019

    • Author(s)
      馬場 健史
    • Organizer
      ダイセルカラム分析スキル向上セミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 定量における課題について2018

    • Author(s)
      和泉 自泰
    • Organizer
      メタボロミクスワークショップ in九大
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] SFC-QqQMSを用いた新規リピドーム解析システム2018

    • Author(s)
      馬場 健史
    • Organizer
      第4回 SFC懇話会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 絶対定量メタボローム解析の実用化に向けた安定同位体内部標準群のバイオプロダクション2018

    • Author(s)
      藤原 由梨,相馬 悠希,高橋 政友,和泉 自泰,馬場 健史
    • Organizer
      第25回 日本生物工学会 九州支部鹿児島大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 技術セミナー:メタボローム解析2018

    • Author(s)
      和泉 自泰
    • Organizer
      新学術領域研究:代謝統合オミクス(代謝アダプテーションのトランスオミクス解析)第1回 若手合宿
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] SFC/MS/MSによるワイドターゲット定量リピドミクス分析2018

    • Author(s)
      和泉 自泰
    • Organizer
      Waters MSフォーラム 2018
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 次世代型 PAL RTC によるメタボロミクス自動前処理システムの開発2018

    • Author(s)
      和泉 自泰
    • Organizer
      第12回 メタボロームシンポジウム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Potential of supercritical fluid extraction and separation technologies in metabolic profiling2018

    • Author(s)
      Takeshi Bamba
    • Organizer
      SFC2018 12th International Conference on Packed-Column SFC
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 細胞培養における代謝解析ツールとしてのメタボロミクス2018

    • Author(s)
      馬場 健史,和泉 自泰
    • Organizer
      第70回 日本生物工学会大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 質量分析のダイナミックレンジ拡張技術の開発とメタボロミクスへの応用2018

    • Author(s)
      中山 泰宗,和泉 自泰,長濱 一弘,松岡 正佳,馬場 健史
    • Organizer
      第70回 日本生物工学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] トランスオミクスに向けた定量メタボローム分析技術の開発2018

    • Author(s)
      馬場 健史
    • Organizer
      第16回 レドックス・ライフイノベーションシンポジウム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Development of metabolomics methodologies and their applications2018

    • Author(s)
      Takeshi Bamba
    • Organizer
      Workshop on Nature Farming and Organic Agriculture
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 先端分析機器を用いたメタボロミクス解析の展望メタボローム解析の要素技術と効果的な利用法2018

    • Author(s)
      馬場 健史
    • Organizer
      食品・環境分析セミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] メタボロミクス有効活用のためにはメタボロミクスの技術をちゃんと理解して使いこなそう!2018

    • Author(s)
      馬場 健史
    • Organizer
      メタボロミクスセミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] メタボロミクスにおける超臨界流体クロマトグラフィーの可能性2018

    • Author(s)
      馬場 健史
    • Organizer
      第13回 アジレントメタボロミクスセミナー 2018
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 脂質代謝の理解を目指した生体脂質分子の一斉定量分析系の構築2018

    • Author(s)
      竹田 浩章,和泉 自泰,Thanai Paxton,田村 翔平,小池 智也,Ying Yu,加藤 紀子,長瀬 勝敏,塩見 雅志,馬場 健史
    • Organizer
      第5回 日本ウサギバイオサイエンス研究会学術集会・WHHLMIウサギ研究発表会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Development of GC/MS based quantitative metabolome analysis methodology by Calibration-Curve-Locking database2018

    • Author(s)
      Kosuke Hata, Yuki Soma, Toshiyuki Yamashita, Masatomo Takahashi, Kuniyo Sugitate, Takeshi Serino, Hiromi Miyagawa, Kenichi Suzuki, Kayoko Yamada, Takatomo Kawamukai, Teruhisa Shiota, Yoshihiro Izumi, Takeshi Bamba
    • Organizer
      13th Annual Conference of the Metabolomics Society (Metabolomics 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Inter-laboratory comparison of metabolite measurements for metabolomics data integration2018

    • Author(s)
      Yoshihiro Izumi, Fumio Matsuda, Akiyoshi Hirayama, Kazutaka Ikeda, Yoshihiro Kita, Kanta Horie, Takeshi Bamba, Yoshiya Oda
    • Organizer
      66th Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a practical SFE-SFC/MS system with a novel split-flow method2018

    • Author(s)
      Miho Sakai, Yoshihiro Hayakawa, Yasuhiro Funada, Takashi Ando, Eiichiro Fukusaki, Takeshi Bamba
    • Organizer
      66th Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] トランスオミクスに資する次世代メタボローム解析技術の開発2018

    • Author(s)
      馬場 健史
    • Organizer
      日本質量分析学会・日本プロテオーム学会 2018 合同大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] メタボロミクスデータの統合に向けた代謝物相対定量値の実験室間比較2018

    • Author(s)
      和泉 自泰,松田 史生,平山 明由,池田 和貴,北 芳博,堀江 勘太,馬場 健史,小田 吉哉
    • Organizer
      日本質量分析学会・日本プロテオーム学会 2018 合同大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 高分解能質量分析を基盤とした外因性化学物質に由来する代謝物の探索手法の開発2018

    • Author(s)
      高橋 政友,和泉 自泰,岩橋 福松,中山 泰宗,岩越 光彦,中尾 素直,大和 誠司,福崎 英一郎,馬場 健史
    • Organizer
      日本質量分析学会・日本プロテオーム学会 2018 合同大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] メタボローム解析における自動サンプル前処理法開発の現状2018

    • Author(s)
      馬場 健史,塩田 晃久
    • Organizer
      日本質量分析学会・日本プロテオーム学会 2018 合同大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 次世代メタボローム解析技術の開発2018

    • Author(s)
      馬場 健史
    • Organizer
      質量分析オープンイノベーション協働ユニットキックオフシンポジウム・蛋白研セミナー”質量分析の未来”
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] メタボロミクスによるマルチマーカープロファイリングの可能性2018

    • Author(s)
      馬場 健史
    • Organizer
      第85回 バイオ研究・ビジネス最前線
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Development of metabolic profiling methodologies by supercritical fluid chromatography/mass spectrometry2018

    • Author(s)
      Takeshi Bamba
    • Organizer
      KEY Forum 2018, Stem Cell Traits and Developmental Systems
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of next generation metabolome analysis technologies for trans-omics2017

    • Author(s)
      Takeshi Bamba
    • Organizer
      The 1st International Symposium for Trans-Omics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 次世代メタボローム解析に向けた新たなクロマトグラフィー質量分析技術の開発2017

    • Author(s)
      和泉 自泰,馬場 健史
    • Organizer
      第28回 クロマトグラフィー科学会議
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 超臨界流体クロマトグラフィー三連四重極型質量分析によるワイドターゲット定量リピドミクス分析法の開発2017

    • Author(s)
      和泉 自泰,竹田 浩章,高橋 政友,Thanai Paxton,加藤 紀子,堀江 真之介,長瀬 勝敏,馬場 健史
    • Organizer
      第11回 メタボロームシンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 新規Calibration-Curve-Locking Databaseを用いたガスクロマトグラフィー質量分析によるメタボローム解析2017

    • Author(s)
      相馬 悠希,山下 俊幸,秦 康祐,高橋 政友,杉立 久仁代,芹野 武,宮川 浩美,鈴木 健一,川向 孝知,塩田 晃久,山田 佳代子,和泉 自泰,馬場 健史
    • Organizer
      第11回 メタボロームシンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] メタボローム解析に資する次世代型多機能オートサンプラー/前処理ロボットによる自動サンプル前処理法の開発2017

    • Author(s)
      相馬 悠希,山下 俊幸,高橋 政友,秦 康祐,川向 孝知,塩田 晃久,山田 佳代子,宮川 浩美,鈴木 健一,杉立 久仁代,芹野 武,和泉 自泰,馬場 健史
    • Organizer
      第11回 メタボロームシンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] イオンクロマトグラフィー高分解能質量分析による動物培養細胞のメタボローム解析2017

    • Author(s)
      和泉 自泰,高橋 政友,鈴木 隆弘,押川 清孝,秦 康祐,中谷 航太, 木村 元一,高原 健太郎,松本 雅記,馬場 健史
    • Organizer
      第11回 メタボロームシンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] メタボロミクスとマトリックス効果2017

    • Author(s)
      和泉 自泰
    • Organizer
      第9回 LC/MSワークショップ
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Metabolic profiling by supercritcal fluid extraction and separation technologies2017

    • Author(s)
      Takeshi Bamba
    • Organizer
      The NJ-ACS Mass Spectrometry Discussion Group October Monthly meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 次世代型多機能オートサンプラー/前処理ロボットによるメタボロミクスに資する自動前処理法の構築2017

    • Author(s)
      相馬 悠希,山下 俊幸,高橋 政友,秦 康祐,川向 孝知,塩田 晃久,山田 佳代子,宮川 浩美,鈴木 健一,杉立 久仁代,芹野 武,和泉 自泰,馬場 健史
    • Organizer
      第69回 日本生物工学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] GC/MSによるメタボローム解析に資する新規Calibration-Curve-Locking Databaseの構築2017

    • Author(s)
      相馬 悠希,山下 俊幸,秦 康祐,高橋 政友,杉立 久仁代,芹野 武,宮川 浩美,鈴木 健一,川向 孝知,塩田 晃久,山田 佳代子,和泉 自泰,馬場 健史
    • Organizer
      第69回 日本生物工学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 定量メタボローム解析のためのGC/MS Calibration-Curve-Locking Databaseの構築2017

    • Author(s)
      馬場 健史
    • Organizer
      第69回 日本生物工学会大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 超臨界流体クロマトグラフィーを用いた代謝物分析2017

    • Author(s)
      馬場 健史
    • Organizer
      第158回 質量分析関西談話会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 定量メタボローム解析のためのGC/MSデータベース構築2017

    • Author(s)
      馬場 健史
    • Organizer
      第12回 アジレントメタボロミクスセミナー 2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Opening a New Chapter in Metabolic Profiling by Supercritical Fluid Extraction and Separation Technologies2017

    • Author(s)
      Takeshi Bamba
    • Organizer
      SFC Asia 2017, 11th International Conference on Packed-Column SFC
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Book] 先端の分析法 第2版2022

    • Author(s)
      富安 範行,馬場 健史
    • Total Pages
      1072
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860437374
    • Related Report
      2021 Annual Research Report
  • [Book] オメガ3脂肪酸の技術と市場2021

    • Author(s)
      竹田浩章,和泉自泰,馬場健史
    • Total Pages
      202
    • Publisher
      シーエムシー出版
    • ISBN
      9784781316048
    • Related Report
      2021 Annual Research Report
  • [Book] 実験医学2021年7月号2021

    • Author(s)
      松本雅記,馬場健史
    • Total Pages
      129
    • Publisher
      羊土社
    • ISBN
      9784758125451
    • Related Report
      2021 Annual Research Report
  • [Book] 食品分野におけるメタボリックプロファイリング2021

    • Author(s)
      馬場 健史
    • Total Pages
      326
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860437442
    • Related Report
      2021 Annual Research Report
  • [Book] メタボロミクス実践ガイド~サンプル調製からデータ解析まで、あなたに合った実験デザインと達人テクニック2021

    • Author(s)
      馬場健史,平山明由,松田史生,津川裕司
    • Total Pages
      334
    • Publisher
      羊土社
    • ISBN
      9784758122511
    • Related Report
      2020 Annual Research Report
  • [Book] 脂質解析ハンドブック~脂質分子の正しい理解と取扱い・データ取得の技術2019

    • Author(s)
      池田和貴, 馬場健史
    • Total Pages
      310
    • Publisher
      羊土社
    • ISBN
      9784758122412
    • Related Report
      2019 Annual Research Report
  • [Book] バイオイノベーションに向けて~バイオテクノロジーの新技術からの新しい視点~ 第3章分析の視点から,4.リピドミクスの展開2019

    • Author(s)
      和泉自泰,馬場健史(分担執筆)
    • Total Pages
      258
    • Publisher
      シーエムシー出版
    • ISBN
      9784781314112
    • Related Report
      2018 Annual Research Report
  • [Book] Lipidomics2017

    • Author(s)
      Yamada, T., Bamba, T.
    • Total Pages
      260
    • Publisher
      Humana Press
    • ISBN
      9781493969449
    • Related Report
      2017 Annual Research Report
  • [Patent(Industrial Property Rights)] 解析システム、解析方法及びプログラム2020

    • Inventor(s)
      馬場健史,中尾素直
    • Industrial Property Rights Holder
      馬場健史,中尾素直
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-174413
    • Filing Date
      2020
    • Related Report
      2020 Annual Research Report
  • [Patent(Industrial Property Rights)] 分析支援装置、分析支援方法、分析支援プログラムおよび分析システム2020

    • Inventor(s)
      藤戸由佳,酒井美穂,馬場健史
    • Industrial Property Rights Holder
      藤戸由佳,酒井美穂,馬場健史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-126551
    • Filing Date
      2020
    • Related Report
      2020 Annual Research Report
  • [Patent(Industrial Property Rights)] 質量分析用標識組成物、代謝物の定量分析法、及び代謝物の動態解析法2019

    • Inventor(s)
      脇村明夏里, 寺内勉, 馬場健史, 和泉自泰, 他4名
    • Industrial Property Rights Holder
      脇村明夏里, 寺内勉, 馬場健史, 和泉自泰, 他4名
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-090121
    • Filing Date
      2019
    • Related Report
      2019 Annual Research Report
  • [Patent(Industrial Property Rights)] メタボローム分析用分離材及びメタボローム分析用カラム2019

    • Inventor(s)
      櫻井惠太, 佛願道男, 馬場健史, 和泉自泰, 中谷航太
    • Industrial Property Rights Holder
      櫻井惠太, 佛願道男, 馬場健史, 和泉自泰, 中谷航太
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Related Report
      2019 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 脂質プロファイリングシステム、脂質プロファイリング方法、及び脂質プロファイリングプログラム2019

    • Inventor(s)
      馬場 健史,中尾 素直,和泉 自泰
    • Industrial Property Rights Holder
      国立大学法人九州大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-033302
    • Filing Date
      2019
    • Related Report
      2018 Annual Research Report
  • [Patent(Industrial Property Rights)] メタボローム分析用分離材およびメタボローム分析用カラム2018

    • Inventor(s)
      櫻井 惠太,佛願 道男,馬場 健史,和泉 自泰,中谷 航太
    • Industrial Property Rights Holder
      日立化成テクノサービス株式会社,国立大学法人九州大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-210643
    • Filing Date
      2018
    • Related Report
      2018 Annual Research Report
  • [Patent(Industrial Property Rights)] 標識代謝物の製造方法、代謝物の定量方法、及び標識代謝物製造キット2017

    • Inventor(s)
      寺内 勉,脇村 明夏里,馬場 健史,和泉 自泰,相馬 悠希
    • Industrial Property Rights Holder
      大陽日酸株式会社,国立大学法人九州大学
    • Industrial Property Rights Type
      特許
    • Patent Publication Number
      2019-024326
    • Filing Date
      2017
    • Acquisition Date
      2019
    • Related Report
      2018 Annual Research Report

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Published: 2017-07-04   Modified: 2024-12-25  

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