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Multi-layer and multi-area data integration mothods for elucidating brain information dynamics

Planned Research

Project AreaBrain information dynamics underlying multi-area interconnectivity and parallel processing
Project/Area Number 17H06310
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionKyoto University

Principal Investigator

Ishii Shin  京都大学, 情報学研究科, 教授 (90294280)

Co-Investigator(Kenkyū-buntansha) 山崎 匡  電気通信大学, 大学院情報理工学研究科, 准教授 (40392162)
Project Period (FY) 2017-06-30 – 2022-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥120,640,000 (Direct Cost: ¥92,800,000、Indirect Cost: ¥27,840,000)
Fiscal Year 2021: ¥27,040,000 (Direct Cost: ¥20,800,000、Indirect Cost: ¥6,240,000)
Fiscal Year 2020: ¥27,040,000 (Direct Cost: ¥20,800,000、Indirect Cost: ¥6,240,000)
Fiscal Year 2019: ¥27,040,000 (Direct Cost: ¥20,800,000、Indirect Cost: ¥6,240,000)
Fiscal Year 2018: ¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000)
Fiscal Year 2017: ¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
Keywords脳情報動態 / カルシウムイメージング / 機能モジュール / エンコーダ / デコーダ / シミュレーション / 画像処理
Outline of Final Research Achievements

We developed a brain decoding method based on fMRI activities during human subjects were performing a decision-making task in an uncertain environment, and examined how the meta recognition is involve in the decision-making process (Katayama, et al., 2022). We examined how hierarchical inference and meta recognition crosstalked in a hierarchical decision-making task. Moreover, we elucidated brain information dynamics that parallel processes observation-based information and knowledge-based information when humans were performing a visual discrimination task.
We developed a decoding method to extract dynamically functional circuity from functional imaging data, and applied it to mice and marmosets Ca2+ imaging from their cortices. We completed functional identification of parietal visual association area of one marmoset.

Academic Significance and Societal Importance of the Research Achievements

不確実環境における意思決定ではメタ認知の関与が想定されるものの、いかに関わるのかはこれまでに明確ではなかった。本研究では、メタ認知が高まることで脳情報動態(動的な脳内表象)を明確にするということを明らかにした点で学術的意義がある。成果が評価され、2022年度のテレコム学際研究賞(奨励賞)を受賞した。
他のサブテーマはいずれも研究は完了しており、今後ハイインパクトの論文としての発表を通じて、学術的意義を謳う予定である。

Report

(6 results)
  • 2022 Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (41 results)

All 2023 2022 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (5 results) Journal Article (21 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 19 results,  Open Access: 18 results) Presentation (15 results) (of which Int'l Joint Research: 6 results,  Invited: 5 results)

  • [Int'l Joint Research] Oxford University(英国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] 深セン大学(中国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] Washinton University(米国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] University of Queensland(オーストラリア)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] University Hospital Freiburg(ドイツ)

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Local and long-distance organization of prefrontal cortex circuits in the marmoset brain2023

    • Author(s)
      Watakabe, A., Skibbe, H., Nakae, K., Abe, H., Ichinohe, N., Rachmadi, M.F., Wang, J., Takaji, M., Mizukami, H., Woodward, A., Gong, R., Hata, J., Van Essen, D.C., Okano, H., Ishii, S., Yamamori, T.
    • Journal Title

      Neuron

      Volume: -

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Deep learning-based image deconstruction method with maintained saliency2022

    • Author(s)
      Fujimoto, K., Hayashi, K., Katayama, R., Lee, S., Liang, Z., Yoshida, W., Ishii, S.
    • Journal Title

      Neural Networks

      Volume: 155 Pages: 224-241

    • DOI

      10.1016/j.neunet.2022.08.015

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Confidence modulates the decodability of scene prediction during partially-observable maze exploration in humans2022

    • Author(s)
      Katayama, R., Yoshida, Y., Ishii, S.
    • Journal Title

      Communications Biology

      Volume: 5 Issue: 1 Pages: 367-367

    • DOI

      10.1038/s42003-022-03314-y

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Tri-view two-photon microscopic image registration and deblurring with convolutional neural networks2022

    • Author(s)
      Lee Sehyung、Kume Hideaki、Urakubo Hidetoshi、Kasai Haruo、Ishii Shin
    • Journal Title

      Neural Networks

      Volume: 152 Pages: 57-69

    • DOI

      10.1016/j.neunet.2022.04.011

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Real-Time Simulation of a Cerebellar Scaffold Model on Graphics Processing Units2021

    • Author(s)
      Kuriyama Rin、Casellato Claudia、D'Angelo Egidio、Yamazaki Tadashi
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 15 Pages: 623552-623552

    • DOI

      10.3389/fncel.2021.623552

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Deep adversarial reinforcement learning with noise compensation by auto-encoder2021

    • Author(s)
      Ohashi, K., Nakanishi, K., Sasaki, W., Yasui, Y., Ishii, S.
    • Journal Title

      IEEE Access

      Volume: - Pages: 143901-143912

    • DOI

      10.1109/access.2021.3121751

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal.2021

    • Author(s)
      Urakubo H, Yagishita S, Kasai H, Kubota Y, Ishii S
    • Journal Title

      PLoS Comput Biol

      Volume: 17 Issue: 9 Pages: e1009364-e1009364

    • DOI

      10.1371/journal.pcbi.1009364

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A meta-Q-learning approach to discriminative correlation filter based visual tracking2021

    • Author(s)
      Kubo, A., Meshgi, K., Ishii, S.
    • Journal Title

      Journal of Intelligence and Robotic Systems

      Volume: 101 Pages: 11-11

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Simulation of a human-scale cerebellar network model on the K computer2020

    • Author(s)
      Yamaura, H., Igarashi, J., Yamazaki, T.
    • Journal Title

      Frontiers in Neuroinformatics

      Volume: 14 Pages: 16-16

    • DOI

      10.3389/fninf.2020.00016

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Meta-Q-Learning Approach to Discriminative Correlation Filter based Visual Tracking2020

    • Author(s)
      Kubo Akihiro、Meshgi Kourosh、Ishii Shin
    • Journal Title

      Journal of Intelligent & Robotic Systems

      Volume: 101 Issue: 1 Pages: 1-11

    • DOI

      10.1007/s10846-020-01273-2

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity2020

    • Author(s)
      Hidetoshi Urakubo, Sho Yagishita, Haruo Kasai, Shin Ishii
    • Journal Title

      PLoS Computational Biology

      Volume: 16 Issue: 7 Pages: 1008078-1008078

    • DOI

      10.1371/journal.pcbi.1008078

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Generative and discriminative model-based approaches to microscopic image restoration and segmentation2020

    • Author(s)
      Ishii Shin、Lee Sehyung、Urakubo Hidetoshi、Kume Hideaki、Kasai Haruo
    • Journal Title

      Microscopy

      Volume: 69 Issue: 2 Pages: 79-91

    • DOI

      10.1093/jmicro/dfaa007

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] EEG-based personal identification method using unsupervised feature extraction and its robustness against intra-subject variability2020

    • Author(s)
      Nishimoto Takashi、Higashi Hiroshi、Morioka Hiroshi、Ishii Shin
    • Journal Title

      Journal of Neural Engineering

      Volume: 17 Issue: 2 Pages: 026007-026007

    • DOI

      10.1088/1741-2552/ab6d89

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] UNI-EM: An Environment for Deep Neural Network-Based Automated Segmentation of Neuronal Electron Microscopic Images2019

    • Author(s)
      Urakubo Hidetoshi、Bullmann Torsten、Kubota Yoshiyuki、Oba Shigeyuki、Ishii Shin
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 19413-19413

    • DOI

      10.1038/s41598-019-55431-0

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Constrained Deep Q-Learning Gradually Approaching Ordinary Q-Learning2019

    • Author(s)
      Shota Ohnishi, Eiji Uchibe, Yotaro Yamaguchi, Kosuke Nakanishi, Yuji Yasui, and Shin Ishii
    • Journal Title

      Frontiers in Neurorobotics

      Volume: 13

    • DOI

      10.3389/fnbot.2019.00103

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An unsupervised EEG decoding system for human emotion recognition2019

    • Author(s)
      Liang Zhen、Oba Shigeyuki、Ishii Shin
    • Journal Title

      Neural Networks

      Volume: 116 Pages: 257-268

    • DOI

      10.1016/j.neunet.2019.04.003

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Identification of animal behavioral strategies by inverse reinforcement learning.2018

    • Author(s)
      Yamaguchi S, Honda N*, Ikeda M, Tsukada Y, Nakano S, Mori I and Ishii S
    • Journal Title

      PLoS Computational Biology

      Volume: 14(5) Issue: 5 Pages: e1006122-e1006122

    • DOI

      10.1371/journal.pcbi.1006122

    • NAID

      120006469168

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Characterization of electroencephalography signals for estimating saliency features in videos2018

    • Author(s)
      Liang Zhen、Hamada Yasuyuki、Oba Shigeyuki、Ishii Shin
    • Journal Title

      Neural Networks

      Volume: 105 Pages: 52-64

    • DOI

      10.1016/j.neunet.2018.04.013

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Zero-shot fMRI decoding with three-dimensional registration based on diffusion tensor imaging2018

    • Author(s)
      Fuchigami, T., Shikauchi, Y., Nakae, K., Shikauchi, M., Ogawa, T., & Ishii, S
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 12342-12342

    • DOI

      10.1038/s41598-018-30676-3

    • NAID

      120006652973

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Computational Methods for Estimating Molecular System from Membrane Potential Recordings in Nerve Growth Cone2018

    • Author(s)
      Yamada, T., Nishiyama, M., Oba, S., Jimbo, H. C., Ikeda, K., Ishii, S., Hong, K., & Sakumura, Y
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1

    • DOI

      10.1038/s41598-018-22506-3

    • NAID

      120006532087

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Inverse tissue mechanics of cell monolayer expansion2018

    • Author(s)
      Kondo Yohei、Aoki Kazuhiro、Ishii Shin
    • Journal Title

      PLOS Computational Biology

      Volume: 14 Issue: 3 Pages: e1006029-e1006029

    • DOI

      10.1371/journal.pcbi.1006029

    • NAID

      120006466609

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Online motion synthesis framework using a simple mass model based on predictive coding2019

    • Author(s)
      Jaepyung Hwang,Shin Ishii,Shigeyuki Oba
    • Organizer
      SIGGRAPH Eurographics Symposium on Computer Animation
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Decoding the scene prediction and its confidence during maze exploration.2019

    • Author(s)
      Katayama, R., Yoshida, W., & Ishii, S.
    • Organizer
      第19回脳と心のメカニズム冬のワークショップ
    • Related Report
      2018 Annual Research Report
  • [Presentation] Artificial intelligence methods for identification of large-scale brain structures.2019

    • Author(s)
      Ishii, S.
    • Organizer
      International Symposium of Brain/MINDS
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Inherent feature connection (I-Con) Map for linking emotion detection: an EEG study.2018

    • Author(s)
      Liang, Z., Oba, S., & Ishii, S.
    • Organizer
      32nd Human Computer Interaction Conference (BHCI 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Reproducing the cognitive function with the robustness against the brain structure and with the efficient learning algorithm.2018

    • Author(s)
      Fujita, Y., & Ishii, S.
    • Organizer
      Computational Neuroscience 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Deep Q-network regularized by adversarial examples.2018

    • Author(s)
      Sasaki, W., Yasui, Y., Nakanishi, K., & Ishii, S.
    • Organizer
      The 28th Annual Conference of the Japanese Neural Network Society
    • Related Report
      2018 Annual Research Report
  • [Presentation] Machine learning-based methods for large-scale neural imaging data2018

    • Author(s)
      Ishii, S
    • Organizer
      International Symposium on Brain Information Dynamics
    • Related Report
      2017 Annual Research Report
  • [Presentation] Individual identification by resting-state EEG using common dictionary learning2017

    • Author(s)
      Nishimoto, T., Morioka, H., & Ishii, S
    • Organizer
      Artificial Neural Networks and Machine Learning - ICANN 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Estimation of the change of agent’s behavioral strategy using state-action history2017

    • Author(s)
      Uchida, S., Oba, S., & Ishii, S
    • Organizer
      Artificial Neural Networks and Machine Learning - ICANN 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Data-driven mimicking neural encoding/decoding systems2017

    • Author(s)
      Ishii, S
    • Organizer
      CRCNS 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Decoding neural decision making2017

    • Author(s)
      Ishii, S
    • Organizer
      Okinawa Computational Neuroscience Course 2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Artificial Intelligence and Connectomics2017

    • Author(s)
      Ishii, S
    • Organizer
      Neuroscience 2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] データベースに基づくブレインマシンインタフェース2017

    • Author(s)
      石井 信
    • Organizer
      電子情報通信学会音声研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 脳イメージングデータ解析のAIの応用と脳機能から学ぶAIの開発2017

    • Author(s)
      石井 信
    • Organizer
      第一回ヒト脳イメージング研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Artificial intelligence and neuroinformatics2017

    • Author(s)
      Ishii, S
    • Organizer
      Advances in Neuroinformatics 2017
    • Related Report
      2017 Annual Research Report
    • Invited

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Published: 2017-07-04   Modified: 2024-01-30  

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