| Budget Amount *help |
¥219,440,000 (Direct Cost: ¥168,800,000、Indirect Cost: ¥50,640,000)
Fiscal Year 2021: ¥40,560,000 (Direct Cost: ¥31,200,000、Indirect Cost: ¥9,360,000)
Fiscal Year 2020: ¥43,680,000 (Direct Cost: ¥33,600,000、Indirect Cost: ¥10,080,000)
Fiscal Year 2019: ¥43,680,000 (Direct Cost: ¥33,600,000、Indirect Cost: ¥10,080,000)
Fiscal Year 2018: ¥46,800,000 (Direct Cost: ¥36,000,000、Indirect Cost: ¥10,800,000)
Fiscal Year 2017: ¥44,720,000 (Direct Cost: ¥34,400,000、Indirect Cost: ¥10,320,000)
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| Outline of Final Research Achievements |
This research has led to the following outcomes: 1) this improved the technology for labeling and manipulating memory trace cell populations using Arc enhancer-promoter technology. 2) This helped create of the highest performance Ca2+ sensor, XCaMP, with enhanced Ca2+ responsiveness and linearity, which has dramatically advanced in vivo multicolor Ca2+ sensing technology; 3) This has elucidation of the significance of the CaMK-CREB-Arc pathway in in vivo physiology and pathology. All of these achievements were made possible by the development of first-in-kin experimental systems established in this grant, and have contributed greatly to advancing the field of brain information dynamics.
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