The spectrum of sex depending on ambient temperature

• Project Area: Spectrum of the Sex: a continuity of phenotypes between female and male
• Project/Area Number: 17H06432
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Tokyo University of Science (2018-2021); Wakayama Medical University (2017)
• Principal Investigator: MIYAGAWA SHINICHI 東京理科大学, 先進工学部生命システム工学科, 准教授 (30404354)
• Co-Investigator(Kenkyū-buntansha): 山田 源 和歌山県立医科大学, 先端医学研究所, 教授 (80174712)
• Project Period (FY): 2017-06-30 – 2022-03-31
• Project Status: Completed (Fiscal Year 2021)
• Budget Amount: ¥97,500,000 (Direct Cost: ¥75,000,000、Indirect Cost: ¥22,500,000); Fiscal Year 2021: ¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000); Fiscal Year 2020: ¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000); Fiscal Year 2019: ¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000); Fiscal Year 2018: ¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000); Fiscal Year 2017: ¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
• Keywords: 性決定 / 温度 / 爬虫類 / 性分化 / 生殖腺 / 環境

Outline of Final Research Achievements

We investigated mechanism of temperature-depending sex determination (TSD) using reptiles as a model. We showed TRPs are essential for reception of environmental signals during TSD. We also showed that epigenetic modifiers and metabolic pathway of pantothenic acid may contribute to TSD at different production temperatures in males and females. These results provide novel insights towards understanding sex determination process in animals.

Academic Significance and Societal Importance of the Research Achievements

常に安定した性比を作り出すことができる遺伝的性決定に対し、温度依存的性決定では性比が天候や産卵場所など不安定な環境に依存するため、生殖戦略上、不利のようにみえる。環境に依存する性決定機構の研究は、絶えず変動する厳しい環境の中で生物が生きていくための知識を与えてくれるとともに、生態系の保全や生物多様性の保存への理解を深めるものとなる。

Research Products

• [Int'l Joint Research] University of Exeter(英国)
• [Int'l Joint Research] Norwegian University of Life Sciences(ノルウェー)
• [Int'l Joint Research] Cincinnati Children's Hospital(米国)
• [Int'l Joint Research] Exeter Univresity(英国)
• [Int'l Joint Research] University of Exeter(英国)
• [Int'l Joint Research] St Cloud State University(米国)
• [Int'l Joint Research] University of Exeter(英国)
• [Int'l Joint Research] NIH(米国)
• [Int'l Joint Research] Hospital for Sick Children(カナダ)
• [Int'l Joint Research] St. Cloud State University(米国)
• [Int'l Joint Research] University of Exeter(英国)
• [Journal Article] Effect of thyroid hormone‐disrupting chemicals on swim bladder inflation and thyroid hormone‐related gene expression in Japanese medaka and zebrafish (2022)
  • Author(s): Horie Yoshifumi、Nomura Miho、Okamoto Konori、Takahashi Chiho、Sato Tomomi、Miyagawa Shinichi、Okamura Hideo、Iguchi Taisen
  • Journal Title: Journal of Applied Toxicology Volume: － Issue: 8 Pages: 1385-1395
  • DOI: 10.1002/jat.4302
  • Peer Reviewed
• [Journal Article] Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development (2022)
  • Author(s): Toyota Kenji、Watanabe Haruna、Hirano Masashi、Abe Ryoko、Miyakawa Hitoshi、Song You、Sato Tomomi、Miyagawa Shinichi、Tollefsen Knut Erik、Yamamoto Hiroshi、Tatarazako Norihisa、Iguchi Taisen
  • Journal Title: Aquatic Toxicology Volume: 243 Pages: 106058-106058
  • DOI: 10.1016/j.aquatox.2021.106058
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes (2021)
  • Author(s): Kajioka Daiki、Suzuki Kentaro、Matsushita Shoko、Hino Shinjiro、Sato Tetsuya、Takada Shuji、Isono Kyoichi、Takeo Toru、Kajimoto Mizuki、Nakagata Naomi、Nakao Mitsuyoshi、Suyama Mikita、DeFalco Tony、Miyagawa Shinichi、Yamada Gen
  • Journal Title: Proceedings of the National Academy of Sciences Volume: 118 Issue: 23
  • DOI: 10.1073/pnas.2024067118
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] New frontiers of developmental endocrinology opened by researchers connecting irreversible effects of sex hormones on developing organs (2021)
  • Author(s): Iguchi Taisen、Sato Tomomi、Nakajima Tadaaki、Miyagawa Shinichi、Takasugi Noboru
  • Journal Title: Differentiation Volume: 118 Pages: 4-23
  • DOI: 10.1016/j.diff.2020.10.003
  • Peer Reviewed
• [Journal Article] Characterization of G protein‐coupled estrogen receptors in Japanese medaka, Oryzias latipes (2020)
  • Author(s): Miyaoku Kaori、Ogino Yukiko、Lange Anke、Ono Ayaka、Kobayashi Tohru、Ihara Masaru、Tanaka Hiroaki、Toyota Kenji、Akashi Hiroshi、Yamagishi Genki、Sato Tomomi、Tyler Charles R.、Iguchi Taisen、Miyagawa Shinichi
  • Journal Title: Journal of Applied Toxicology Volume: - Issue: 9 Pages: 1390-1399
  • DOI: 10.1002/jat.4130
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A newly developed genetic sex marker and its application to understanding chemically induced feminisation in roach (Rutilus rutilus) (2020)
  • Author(s): Lange Anke、Paris Josephine R.、Gharbi Karim、Cezard Timothee、Miyagawa Shinichi、Iguchi Taisen、Studholme David J.、Tyler Charles R.
  • Journal Title: Molecular Ecology Resources Volume: 20 Issue: 4 Pages: 1007-1022
  • DOI: 10.1111/1755-0998.13166
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Hedgehog signaling regulates the basement membrane remodeling during folliculogenesis in the neonatal mouse ovary (2020)
  • Author(s): Terauchi Karin J.、Miyagawa Shinichi、Iguchi Taisen、Sato Tomomi
  • Journal Title: Cell and Tissue Research Volume: 381 Issue: 3 Pages: 555-567
  • DOI: 10.1007/s00441-020-03222-9
  • Peer Reviewed
• [Journal Article] Expression dynamics of genes in the hypothalamic-pituitary-thyroid (HPT) cascade and their responses to 3,3′,5-triiodo-l-thyronine (T3) highlights potential vulnerability to thyroid-disrupting chemicals in zebrafish (Danio rerio) embryo-larvae (2020)
  • Author(s): Parsons Aoife E.、Lange Anke、Hutchinson Thomas H.、Miyagawa Shinichi、Iguchi Taisen、Kudoh Tetsuhiro、Tyler Charles R.
  • Journal Title: Aquatic Toxicology Volume: 225 Pages: 105547-105547
  • DOI: 10.1016/j.aquatox.2020.105547
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Estrogen Receptor 1 (ESR1) Agonist Induces Ovarian Differentiation and Aberrant Mullerian Duct Development in the Chinese Soft-shelled Turtle, Pelodiscus sinensis (2020)
  • Author(s): Toyota Kenji、Masuda Shoichiro、Sugita Sarina、Miyaoku Kaori、Yamagishi Genki、Akashi Hiroshi、Miyagawa Shinichi
  • Journal Title: Zoological Studies Volume: 59
  • Peer Reviewed / Open Access
• [Journal Article] Bmp4 is an essential growth factor for the initiation of genital tubercle (GT) outgrowth. (2019)
  • Author(s): Kajioka D, Suzuki K, Nakada S, Matsushita S, Miyagawa S, Takeo T, Nakagata N, Yamada G.
  • Journal Title: Congenit. Anom. (Kyoto) Volume: in press Issue: 1 Pages: 0-0
  • DOI: 10.1111/cga.12326
  • NAID: 210000012752
  • Peer Reviewed
• [Journal Article] Hedgehog Signaling for Urogenital Organogenesis and Prostate Cancer: An Implication for the Epithelial?Mesenchyme Interaction (EMI) (2019)
  • Author(s): Hyuga Taiju、Alcantara Mellissa、Kajioka Daiki、Haraguchi Ryuma、Suzuki Kentaro、Miyagawa Shinichi、Kojima Yoshiyuki、Hayashi Yutaro、Yamada Gen
  • Journal Title: International Journal of Molecular Sciences Volume: 21 Issue: 1 Pages: 58-58
  • DOI: 10.3390/ijms21010058
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Regulatory roles of epithelial-mesenchymal interaction (EMI) during early and androgen dependent external genitalia development (2019)
  • Author(s): Hyuga T, Suzuki K, Acebedo AR, Hashimoto D, Kajimoto M, Miyagawa S, Enmi JI, Yoshioka Y, Yamada G.
  • Journal Title: Differentiation Volume: 110 Pages: 29-35
  • DOI: 10.1016/j.diff.2019.08.004
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The Role of Fgf Signaling on Epithelial Cell Differentiation in Mouse Vagina (2019)
  • Author(s): HIRANO YU、SUZUKI KENTARO、IGUCHI TAISEN、YAMADA GEN、MIYAGAWA SHINICHI
  • Journal Title: In Vivo Volume: 33 Issue: 5 Pages: 1499-1505
  • DOI: 10.21873/invivo.11630
  • Peer Reviewed
• [Journal Article] Diethylstilbestrol Alters the Expression of Activins in the Neonatal Mouse Ovary In Vitro (2019)
  • Author(s): OIKAWA SACHIYO、KOBAYASHI SACHIYO、MIYAGAWA SHINICHI、IGUCHI TAISEN、SATO TOMOMI
  • Journal Title: In Vivo Volume: 33 Issue: 4 Pages: 1095-1102
  • DOI: 10.21873/invivo.11578
• [Journal Article] Molecular mechanisms and tissue targets of brominated flame retardants, BDE-47 and TBBPA, in embryo-larval life stages of zebrafish (Danio rerio) (2019)
  • Author(s): Parsons Aoife、Lange Anke、Hutchinson Thomas H.、Miyagawa Shinichi、Iguchi Taisen、Kudoh Tetsuhiro、Tyler Charles R.
  • Journal Title: Aquatic Toxicology Volume: 209 Pages: 99-112
  • DOI: 10.1016/j.aquatox.2019.01.022
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice. (2019)
  • Author(s): Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G.
  • Journal Title: Commun. Biol. Volume: eCollection Issue: 1 Pages: 95-95
  • DOI: 10.1038/s42003-019-0336-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Single Nucleotide Polymorphisms of HAAO and IRX6 Genes as Risk Factors for Hypospadias. (2019)
  • Author(s): Kojima Y, Koguchi T, Mizuno K, Sato Y, Hoshi S, Hata J, Nishio H, Hashimoto D, Matsushita S, Suzuki K, Miyagawa S, Hui CC, Tanikawa C, Murakami Y, Yamada G, Hayashi Y, Matsuda K.
  • Journal Title: J Urol. Volume: 201(2) Issue: 2 Pages: 386-392
  • DOI: 10.1016/j.juro.2018.07.050
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Functional distinctions associated with the diversity of sex steroid hormone receptors ESR and AR. (2018)
  • Author(s): Ogino Y, Tohyama S, Kohno S, Toyota K, Yamada G, Yatsu R, Kobayashi T, Tatarazako N, Sato T, Matsubara H, Lange A, Tyler CR, Katsu Y, Iguchi T, Miyagawa S.
  • Journal Title: J Steroid Biochem Mol Biol. Volume: 184 Pages: 38-46
  • DOI: 10.1016/j.jsbmb.2018.06.002
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Regulation of masculinization: androgen signalling for external genitalia development (2018)
  • Author(s): Matsushita Shoko、Suzuki Kentaro、Murashima Aki、Kajioka Daiki、Acebedo Alvin Resultay、Miyagawa Shinichi、Haraguchi Ryuma、Ogino Yukiko、Yamada Gen
  • Journal Title: Nature Reviews Urology Volume: 印刷中 Issue: 6 Pages: 358-368
  • DOI: 10.1038/s41585-018-0008-y
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Identification of hepatic thyroid hormone-responsive genes in neonatal rats: Potential targets for thyroid hormone-disrupting chemicals. (2018)
  • Author(s): Fujimoto N., Kitamura S., Uramaru N., Miyagawa S., Iguchi T.
  • Journal Title: Toxicology Letters Volume: 286 Pages: 48-53
  • DOI: 10.1016/j.toxlet.2018.01.005
  • Peer Reviewed / Open Access
• [Journal Article] Divergent responsiveness of two isoforms of the estrogen receptor to mixtures of contaminants of emerging concern in four vertebrates. (2018)
  • Author(s): Kohno S, Katsu Y, Cipoletti N, Wang LC, Jorgenson ZG, Miyagawa S, Schoenfuss HL.
  • Journal Title: J Appl Toxicol Volume: 38 Issue: 5 Pages: 705-713
  • DOI: 10.1002/jat.3577
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Juvenile hormone-independent function of Kruppel homolog 1 in early development of water flea Daphnia pulex (2018)
  • Author(s): Miyakawa Hitoshi、Watanabe Minae、Araki Marina、Ogino Yukiko、Miyagawa Shinichi、Iguchi Taisen
  • Journal Title: Insect Biochemistry and Molecular Biology Volume: 93 Pages: 12-18
  • DOI: 10.1016/j.ibmb.2017.12.007
  • Peer Reviewed
• [Journal Article] Regulation of masculinization: androgen signalling for external genitalia development. (2018)
  • Author(s): Matsushita S, Suzuki K, Murashima A, Kajioka D, Acebedo AR, Miyagawa S, Haraguchi R, Ogino Y, Yamada G.
  • Journal Title: Nat Rev Urol
  • Peer Reviewed
• [Journal Article] Establishment of estrogen receptor 1 (ESR1)-knockout medaka; ESR1 is dispensable for sexual development and reproduction in medaka, Oryzias latipes. (2017)
  • Author(s): Tohyama S, Ogino Y, Lange A, Myosho T, Kobayashi T, Hirano Y, Yamada G, Sato T, Tatarazako N, Tyler CR, Iguchi T, Miyagawa S.
  • Journal Title: Dev Growth Diff Volume: 59 Issue: 6 Pages: 552-561
  • DOI: 10.1111/dgd.12386
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Altered expression of Olr59, Ethe1, and Slc10a2 genes in the liver of F344 rats by neonatal thyroid hormone disruption. (2017)
  • Author(s): Matsubara K et al.
  • Journal Title: J Appl Toxicol Volume: - Issue: 9 Pages: 1030-1035
  • DOI: 10.1002/jat.3452
  • Peer Reviewed / Open Access
• [Journal Article] Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals. (2017)
  • Author(s): Lange A, Corcorana J, Miyagawa S, Iguchi T, Winter MJ, Tyler CR.
  • Journal Title: Toxicol In Vitro Volume: 41 Pages: 114-122
  • DOI: 10.1016/j.tiv.2017.02.023
  • Peer Reviewed / Int'l Joint Research
• [Presentation] マウス子宮間質細胞のエストロゲン受容体αの役割 (2021)
  • Author(s): 湊谷紗妃、妹尾衣里子、豊田賢治、宮川信一
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] マウスの外生殖器形成及び性分化疾患メカニズムの解析 (2021)
  • Author(s): 長谷川真子、内田翔、豊田賢治、宮川信一
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] マウス膣の間質細胞に発現するエストロゲン受容体1の機能解析 (2021)
  • Author(s): 妹尾衣里子、湊谷紗妃、豊田賢治、宮川信一
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] Approaches for studying endocrine disrupters acting though nuclear receptors in fish, Japanese medaka (Oryzias latipes) (2021)
  • Author(s): Miyagawa S, Iguchi T, Lange A, Tyler, CR.
  • Organizer: 23th UK-Japan Annual Scientific Workshop on EDCs
  • Int'l Joint Research
• [Presentation] 羊膜類の糖新生酵素g6pc1の遺伝子重複とその生理学的意義の解明 (2021)
  • Author(s): 山岸弦記、朴民根、宮川信一
  • Organizer: 日本比較内分泌学会第45回大会
• [Presentation] 幼若ホルモンがズワイガニのオスらしさを決める？ (2021)
  • Author(s): 豊田賢治、山本岳男、宮川信一、井原賢、森友子、重信秀治、大平剛
  • Organizer: 日本動物学会第92回大会
• [Presentation] ニホンヤモリにおける温度感受性TRPチャネルと高温刺激に対する忌避行動の関連 (2021)
  • Author(s): 柳川紗良、赤司寛志、宮川信一
  • Organizer: 日本進化学会第23回大会
• [Presentation] 温度センサータンパク質TRP及び体温調節行動における温度感受性の相関進化 (2020)
  • Author(s): 赤司寛志、宮川信一
  • Organizer: 東京理科大学生物環境イノベーション研究部門公開シンポジウム
• [Presentation] 三次元イメージング技術を用いた総排泄腔分割の解析:発生異常メカニズムの解明に向けて (2020)
  • Author(s): 松丸大輔、村嶋亜紀、宮川信一、原田理代、山田源、中西剛
  • Organizer: フォーラム2020：衛生薬学・環境トキシコロジー
• [Presentation] 総排泄腔分割の三次元イメージング解析：発生毒性メカニズムの解明に向けて (2020)
  • Author(s): 松丸大輔、村嶋亜紀、宮川信一、原田理代、山田源、中西剛
  • Organizer: 日本薬学会第140年会
• [Presentation] Molecular mechanisms underlying temperature-dependentsex determination in reptiles (2020)
  • Author(s): Miyagawa S
  • Organizer: 第97回日本生理学会大会
  • Invited
• [Presentation] ミナミメダカを用いた環境医薬品5種に対する魚類行動影響評価 (2019)
  • Author(s): 莚平裕次、富田将基、井原賢、中田典秀、宮川信一、村田良介、長江真樹 、征矢野清
  • Organizer: 日本内分泌攪乱化学物質学会第22回研究発表会
• [Presentation] 水圏生態系に及ぼす環境医薬品の影響評価 (2019)
  • Author(s): 征矢野清、長江真樹、莚平裕次、村田良介、井原賢、中田典秀、張晗、宮川信一、宮奥香理
  • Organizer: 日本内分泌攪乱化学物質学会第22回研究発表会
• [Presentation] Elucidation of molecular mechanism underlying temperature-sensing during sex determination in alligator and turtles. (2019)
  • Author(s): Akashi H, Toyota K, Kohno S, Iguchi T, Miyagawa S
  • Organizer: 5th Biennial North American Society for Comparative Endocrinology
  • Int'l Joint Research
• [Presentation] The significance of temperature-sensing in thermoregulatory behavior in Anolis lizard. (2019)
  • Author(s): Akashi H, Toyota K, Kohno S, Iguchi T, Miyagawa S
  • Organizer: 5th Biennial North American Society for Comparative Endocrinology
  • Int'l Joint Research / Invited
• [Presentation] 温度環境に依存する爬虫類の性決定 (2019)
  • Author(s): 宮川信一
  • Organizer: 第66回日本生態学会大会
  • Invited
• [Presentation] Approaches for studying endocrine disruption and estrogen receptors in medaka (2018)
  • Author(s): Miyagawa S, Tohyama S, Ogino Y, Kobayashi T, Lange A, Tyler CR, Iguchi T
  • Organizer: 日本内分泌攪乱化学物質学会第21回研究発表会
  • Invited
• [Presentation] 環境に依存する性と生殖の研究 (2018)
  • Author(s): 宮川信一
  • Organizer: 日本比較内分泌学会第43回大会
  • Invited
• [Presentation] メダカエストロゲン受容体(Esr1)の生殖に対する機能解析 (2017)
  • Author(s): 遠山早紀、荻野由紀子、明正大純、佐藤友美、小林亨、井口泰泉、宮川信一
  • Organizer: 日本内分泌攪乱化学物質学会第20回研究発表会
• [Presentation] Time-series transcriptome approach for deciphering the male sex determining mechanisms via juvenile hormone in the water flea Daphnia pulex (2017)
  • Author(s): Toyota K, Iguchi T, Yamada G, Miyagawa S, Colbourne JK
  • Organizer: 日本内分泌攪乱化学物質学会第20回研究発表会
• [Presentation] 温度環境に依存する爬虫類の性決定システム (2017)
  • Author(s): 宮川信一、豊田賢治、谷津遼平、井口泰泉
  • Organizer: 日本比較内分泌学会第42回大会
• [Presentation] マウス膣上皮細胞の分化におけるFgfシグナルの関与 (2017)
  • Author(s): 平野優、山田源、宮川信一
  • Organizer: 日本比較内分泌学会第42回大会
• [Presentation] エストロゲン受容体1（Esr1/ERa）ノックアウトメダカの表現型解析 (2017)
  • Author(s): 遠山早紀、荻野由紀子、明正大純、佐藤友美、小林亨、井口泰泉、宮川信一
  • Organizer: 日本比較内分泌学会第42回大会
• [Presentation] 時系列トランスクリプトームから迫るミジンコの環境依存型性決定の分子機構 (2017)
  • Author(s): 豊田賢治、John K Colbourne、井口泰泉、宮川信一
  • Organizer: 日本比較内分泌学会第42回大会（
• [Presentation] メダカPPARγのクローニングと代謝異常に関する解析 (2017)
  • Author(s): 遠山早紀、明正大純、佐藤友美、井口泰泉、小林亨、宮川信一
  • Organizer: 日本動物学会第88回大会
• [Presentation] マウス膣上皮細胞増殖と分化に関するエストロゲン受容体の機能解析 (2017)
  • Author(s): 山田源、平野優、井口泰泉、宮川信一
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] 温度環境に依存する爬虫類の性決定機構 (2017)
  • Author(s): 第2回Biothermology研究会
  • Organizer: 第2回Biothermology研究会
  • Invited
• [Presentation] 魚類エストロゲン受容体のリガンド応答性の研究―進化と多様性を考慮して (2017)
  • Author(s): 宮川信一、遠山早紀、井口泰泉
  • Organizer: 第23回生物化学的測定研究会（松山）
  • Invited
• [Presentation] Approaches for studying endocrine disruption and estrogen receptor subtypes in fish (2017)
  • Author(s): Shinichi Miyagawa, Saki Tohyama, Taisen Iguchi
  • Organizer: 19th UK-Japan Annual Scientific Workshop on EDCs
  • Int'l Joint Research
• [Presentation] 温度環境に依存する爬虫類の 性決定システム (2017)
  • Author(s): 宮川信一
  • Organizer: 第2回次世代生命科学の研究会
  • Invited
• [Book] Environmental control on sex differentiation in reptiles. In: Reproductive and Developmental Strategies: the Continuity of Life. Part 2: Diversity in Sex Differentiation. (2018)
  • Author(s): Miyagawa S, Yatsu R, Iguchi T.
  • Publisher: Springer
• [Remarks] 東京理科大学宮川研究室
  • URL: https://sites.google.com/site/miyashinchi/