| Budget Amount *help |
¥94,000,000 (Direct Cost: ¥94,000,000)
Fiscal Year 2010: ¥18,800,000 (Direct Cost: ¥18,800,000)
Fiscal Year 2009: ¥18,800,000 (Direct Cost: ¥18,800,000)
Fiscal Year 2008: ¥18,800,000 (Direct Cost: ¥18,800,000)
Fiscal Year 2007: ¥18,800,000 (Direct Cost: ¥18,800,000)
Fiscal Year 2006: ¥18,800,000 (Direct Cost: ¥18,800,000)
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| Research Abstract |
The purpose of this study is to understand the molecular mechanism of the replication and pathogenesis of an important human pathogen, herpes simplex virus (HSV). The present studies have revealed the novel functions and roles of HSV gene products. Moreover, cellular proteins, INSM1 and tankylase 1 have been shown to play important roles in the replication of HSV. These observations were useful for developing vaccines and oncolytic viruses.
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