Functional interactions between hormone-sensor and osmo-sensor in the central regulation of body fluid osmolality

• Project Area: Molecular interaction and modal shift of cellular sensors
• Project/Area Number: 18077006
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: University of Occupational and Environmental Health, Japan
• Principal Investigator: UETA Yoichi University of Occupational and Environmental Health, Japan, 医学部, 教授 (10232745)
• Co-Investigator(Kenkyū-buntansha): NAGATOMO Toshihisa 産業医科大学, 大学病院, 准教授 (50258604) ; FUJIHARA Hiroaki 徳島大学, 大学院・ヘルスバイオサイエンス部, 助教 (10369051) ; YOKOYAMA Toru 自治医科大学, 医学部, 助教 (80425321)
• Project Period (FY): 2006 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥63,800,000 (Direct Cost: ¥63,800,000); Fiscal Year 2010: ¥12,600,000 (Direct Cost: ¥12,600,000); Fiscal Year 2009: ¥12,500,000 (Direct Cost: ¥12,500,000); Fiscal Year 2008: ¥12,900,000 (Direct Cost: ¥12,900,000); Fiscal Year 2007: ¥12,900,000 (Direct Cost: ¥12,900,000); Fiscal Year 2006: ¥12,900,000 (Direct Cost: ¥12,900,000)
• Keywords: セルセンサー / 浸透圧 / バゾプレッシン / 生体リズム / 緑色蛍光タンパク / トランスジェニック動物 / 視交叉上核 / 時計遺伝子 / モーダルシフト / 生体分子 / 神経ペプチド / シチプス / TRP / GFP / ホルモン / グレリン / パッチクランプ法 / シナプス入力 / 視床下部 / アンジオテンシンII / サリューシン

Research Abstract

The purpose of the study was to examine the relationship between sensing the hormones (hormone-sensor) secreted by changes of osmolality and sensing the osmolality (osmo-sensor). In particular, we examined arginine vasopressin (AVP) system and drinking behavior. We obtained significant results as follow. (1) In in vitro brain slice preparation including the supraoptic nucleus (SON) that contain AVP neurons whole-cell patch-clamp recordings revealed effects of physiologically active substances on the excitatory and inhibitory synaptic currents in the SON. (2) Whole-cell patch-clamp recordings from an isolated single AVP-eGFP neuron revealed the electrophysiological properties. The diurnal changes of the expression of the several genes and electrophysiological properties were determined in the AVP-eGFP neurons in the suprachiasmatic nucleus that is known to be a circadian center. (3) Central effects of angiotensin II etc on drinking behavior were examined in rats.

Research Products

• [Journal Article] Possible contribution of pannexin channel to ATP-induced currents in vitro in vasopressin neurons isolated from the rat supraoptic nucleus. (2011)
  • Author(s): Ohbuchi, T., Yokoyama, T., Saito, T., Ohkubo, J., Suzuki, H., Ishikura, T., Katoh, A., Fujihara, H., Hashimoto, H., Suzuki, H., Ueta, Y.
  • Journal Title: Brain Research in press
  • Peer Reviewed
• [Journal Article] V_2 receptor-mediated autocrine role of somatodendritic release of AVP in rat vasopressin neurons under hypo-osmotic conditions. (2011)
  • Author(s): Sato, K., Numata, T., Saito, T., Ueta, Y., Okada, Y.
  • Journal Title: Science Signaling 4(157)(Cover article of the issue)
  • Peer Reviewed
• [Journal Article] Allylisothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the sipraoptic nucleus in rats. (2011)
  • Author(s): Yokoyama, T., Ohbuchi, T., Saito, T., Fujihara, H., Minami, K., Nagatomo, T., Uezono, Y., Ueta, Y.
  • Journal Title: European Journal of Pharmacology 655(1-3) Pages: 31-37
  • Peer Reviewed
• [Journal Article] Hypothalamic vasopressin response to stress and various physiological stimuli : Visualization in transgenic animal models. (2011)
  • Author(s): Ueta, Y., Dayanithi, G., Fujihara, H.
  • Journal Title: Hormones and Behavior 59(2) Pages: 221-226
  • Peer Reviewed
• [Journal Article] Highly visible expression of an oxytocin-monomeric red fluorescent protein 1 fusion gene in the hypothalamus and posterior pituitary of transgenic rats. (2011)
  • Author(s): Katoh, A.Fujihara, H.Ohbuchi, T.Onaka, T.Hashimoto, T.Kawata, M.Suzuki, H., Ueta, Y.
  • Journal Title: Endocrinology Volume: (in press)
  • Peer Reviewed
• [Journal Article] V2 receptor-mediated autocrine role of somato-dendritic release of arginine vasopressin in volume regulation of rat supraoptic vasopressin neurons under hypoosmotis conditions. (2011)
  • Author(s): Sato, K.Numata, T.Ueta, Y., Okada, Y.
  • Journal Title: Science Signaling Volume: 4(157)
  • Peer Reviewed
• [Journal Article] Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the sipraoptic nucleus in rats. (2011)
  • Author(s): Yokoyama, T.Ohbuchi, T.Saito, T.Fujihara, H.Minami, K.Nagatomo, T.Uezono, Y., Ueta, Y.
  • Journal Title: European Journal of Pharmacology Volume: 655(1-3) Pages: 31-37
  • Peer Reviewed
• [Journal Article] Hypothalamic vasopressin response to stress and various physiological stimuli : Visualization in transgenic animal models. (2011)
  • Author(s): Ueta, Y.Dayanithi, G.Fujihara, H.
  • Journal Title: Hormones and Behavior Volume: 59(2) Pages: 221-226
  • Peer Reviewed
• [Journal Article] Similar changes of hypothalamic feeding-regulating peptides mRNAs and plasma leptin levels in PTHrP-, LIF-secreting tumors-induced cachectic rats and adjuvant arthritic rats. (2011)
  • Author(s): Suzuki, H.Hashimoto, H.Kawasaki, M.Watanabe, M.Otsubo, H.Ishikura, T.Fujihara, H.Ohnishi, H.Onuma, E.Yamada-Okabe, H.Takuwa, Y.Ogata, E.Nakamura, T., Ueta, Y.
  • Journal Title: International Journal of Cancer Volume: 28(9) Pages: 2215-2223
  • Peer Reviewed
• [Journal Article] Diurnal changes of arginine vasopressin-enhanced green fluorescent protein fusion transgene expression in the rat suprachiasmatic nucleus. (2010)
  • Author(s): Maruyama, T., Ohbuchi, T., Fujihara, H., Shibata, M., Mori, K., Murphy, D., Dayanithi, G., Ueta, Y.
  • Journal Title: Peptides 31(11) Pages: 2089-2093
  • NAID: 10028237717
  • Peer Reviewed
• [Journal Article] Modulators of BK and SK channels alter electrical activity in vitro in single vasopressin neurons isolated from the rat supraoptic nucleus. (2010)
  • Author(s): Ohbuchi, T., Yokoyama, T., Saito, T., Suzuki, H., Fujihara, H., Katoh, A., Otsubo, H., Ishikura, T., Ueta, Y.
  • Journal Title: Neuroscience Letters 484(1) Pages: 26-29
  • Peer Reviewed
• [Journal Article] Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus. (2010)
  • Author(s): Ohbuchi, T., Sato, K., Suzuki, H., Okada, Y., Dayanithi, G., Murphy, D., Ueta, Y.
  • Journal Title: Journal of Physiology (London) 588(12) Pages: 2147-2162
  • Peer Reviewed
• [Journal Article] Induction of the arginine vasopressin-enhanced green fluorescent protein fusion transgene in the rat locus soerules. (2010)
  • Author(s): Todoroki, M., Ueta, Y., Fujihara, H., Otsubo, H., Shibata, M., Hashimoto, H., Kobayashi, M., Sakamoto, H., Kawata, M., Dayanithi, G., Murphy, D., Hiro, H., Takahashi, K., Nagata, S.
  • Journal Title: Stress 13(4) Pages: 281-291
  • Peer Reviewed
• [Journal Article] Centrally administered relaxin-3 induces Fos expression in the osmosensitive areas in rat brain and facilitates water intake. (2010)
  • Author(s): Otsubo, H., Onaka, T., Suzuki, H., Katoh, A., Ohbuchi, T., Todoroki, M., Kobayashi, M., Fujihara, H., Yokoyama, T., Matsumoto, T., Ueta, Y.
  • Journal Title: Peptides 31(6) Pages: 1124-1130
  • Peer Reviewed
• [Journal Article] Electrophysiological identification of the functional presunaptic nerve terminal on an isolated single vasopressin neurone of the rat supraoptic nucleus. (2010)
  • Author(s): Ohbuchi, T., Yokoyama, T., Fujihara, H., Suzuki, H., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 22(5) Pages: 413-419
  • Peer Reviewed
• [Journal Article] TRPV1 gene deficiency attenuates miniature EPSCs potentiation induced by mannitol and angiotensin II in supraoptic magnocellular neurons. (2010)
  • Author(s): Yokoyama, T., Saito, T., Ohbuchi, T., Hashimoto, H., Suzuki, H., Otsubo, H., Fujihara, H., Nagatomo, T., Ueta, Y.
  • Journal Title: Journal of Neuroscience 30(3) Pages: 876-884
  • Peer Reviewed
• [Journal Article] Centrally administered ghrelin potently inhibits water intake induced by angiotensin II and hypovolemia in rats. (2010)
  • Author(s): Hashimoto, H., Otsubo, H., Fujihara, H., Suzuki, H., Ohbuchi, T., Yokoyama, T., Takei, Y., Ueta, Y.
  • Journal Title: The Journal of Physiological Sciences 60(1) Pages: 19-25
  • NAID: 10027711142
  • Peer Reviewed
• [Journal Article] (2010) Diurnal changes of arginine vasopressin-enhanced green fluorescent protein fusion transgene expression in the rat suprachiasmatic nucleus. (2010)
  • Author(s): Maruyama, T.Ohbuchi, T.Fujihara, H.Shibata, M.Mori, K.Murphy, D.Dayanithi, G., Ueta, Y.
  • Journal Title: Peptides Volume: 31(11) Pages: 2089-2093
  • Peer Reviewed
• [Journal Article] Modulators of BK and SK channels alter electrical activity in vitro in single vasopressin neurons isolated from the rat supraoptic nucleus. (2010)
  • Author(s): Ohbuchi, T.Yokoyama, T.Saito, T.Suzuki, H.Fujihara, H.Katoh, A.Otsubo, H.Ishikura, T., Ueta, Y.
  • Journal Title: Neuroscience Letters Volume: 484(1) Pages: 26-29
  • Peer Reviewed
• [Journal Article] Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus. (2010)
  • Author(s): Ohbuchi, T.Sato, K.Suzuki, H.Okada, Y.Dayanithi, G.Murphy, D., Ueta, Y.
  • Journal Title: Journal of Physiology (London) Volume: 588(12) Pages: 2147-2162
  • Peer Reviewed
• [Journal Article] Induction of the arginine vasopressin-enhanced green fluorescent protein fusion transgene in the rat locus soerules. (2010)
  • Author(s): Todoroki, M.Ueta, Y.Fujihara, H.Otsubo, H.Shibata, M.Hashimoto, H.Kobayashi, M.Sakamoto, H.Kawata, M.Dayanithi, G Murphy, D.Hiro, H.Takahashi, K., Nagata, S.
  • Journal Title: Stress Volume: 13(4) Pages: 281-291
  • Peer Reviewed
• [Journal Article] Centrally administered relaxin-3 induces Fos expression in the osmosensitive areas in rat brain and facilitates water intake. (2010)
  • Author(s): Otsubo, H.Onaka, T.Suzuki, H.Katoh, A.Ohbuchi, T.Todoroki, M.Kobayashi, M.Fujihara, H.Yokoyama, T.Matsumoto, T., Ueta, Y.
  • Journal Title: Peptides Volume: 31(6) Pages: 1124-1130
  • Peer Reviewed
• [Journal Article] Electrophysiological identification of the functional presunaptic nerve terminal on an isolated single vasopressin neurone of the rat supraoptic nucleus. (2010)
  • Author(s): Ohbuchi, T.Yokoyama, T.Fujihara, H.Suzuki, H., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology Volume: 22(5) Pages: 413-419
  • Peer Reviewed
• [Journal Article] Specific expression of an oxytocin-enhanced cyan fluorescent protein fusion transgene in the rat hypothalamus and posterior pituitary. (2010)
  • Author(s): Katoh, A.Fujihara, H.Ohbuchi, T.Onaka, T.Young, W.S.Dayanithi, G.Yamasaki, Y.Kawata, M.Suzuki, H.Otsubo, H.Suzuki, H.Murphy, D., Ueta, Y.
  • Journal Title: Journal of Endocrinology Volume: 204(3) Pages: 275-285
  • Peer Reviewed
• [Journal Article] TRPV1 gene deficiency attenuates miniature EPSCs potentiation induced by mannitol and angiotensin II in supraoptic magnocellular neurons. (2010)
  • Author(s): Yokoyama, T.Saito, T.Ohbuchi, T.Hashimoto, H.Suzuki, H.Otsubo, H.Fujihara, H.Nagatomo, T.Ueta, Y
  • Journal Title: Journal of Neuroscience Volume: 30(3) Pages: 876-884
  • Peer Reviewed
• [Journal Article] Centrally administered ghrelin potently inhibits water intake induced by angiotensin II and hypovolemia in rats. (2010)
  • Author(s): Y.Hashimoto, H.Otsubo, H.Fujihara, H.Suzuki, H.Ohbuchi, T.Yokoyama, T.Takei, Y.Ueta, Y
  • Journal Title: The Journal of Physiological Sciences Volume: 60(1) Pages: 19-25
  • NAID: 10027711142
  • Peer Reviewed
• [Journal Article] Centrally administered ghrelin potently inhibits water intake induced by angiotensin II and hypovolemia in rats (2010)
  • Author(s): Hashimoto, H.et al.
  • Journal Title: The Journal of Physiological Sciences 60 Pages: 19-25
  • Peer Reviewed
• [Journal Article] TRPV1 gene deficiency attenuates miniature EPSCs potentiation induced by mannitol and angiotensin II in supraoptic magnocellular neurons (2010)
  • Author(s): 横山徹 et al.
  • Journal Title: Journal of Neuroscience 30(3) Pages: 876-884
  • Peer Reviewed
• [Journal Article] Pathophysiological roles of galanin-like peptide in the hypothalamus and posterior pituitary gland (2010)
  • Author(s): Suzuki, H.et al.
  • Journal Title: Pathophysiology(Review) 17 Pages: 135-140
  • Peer Reviewed
• [Journal Article] Specific expression of an oxytocin-enhanced cyan fluorescent protein fusion transgene in the rat hypothalamus and posterior pituitary (2010)
  • Author(s): Katoh, A.et al.
  • Journal Title: Journal of Endocrinology 204 Pages: 275-285
  • Peer Reviewed
• [Journal Article] Induction of the arginine vasopressin-enhanced green fluorescent prote in fusion transgene in the rat locus coeruleus (2010)
  • Author(s): Todoroki, M.et al.
  • Journal Title: Stress (in press)
  • Peer Reviewed
• [Journal Article] Electrophysiological identification of the functional presynaptic nerve terminal on an isolated single vasopressin neurone of the rat supraoptic nucleus (2010)
  • Author(s): Ohbuchi, T.et al.
  • Journal Title: Journal of Neuroendocrinology (in press)
  • Peer Reviewed
• [Journal Article] Centrally administered relaxin-3 induces Fos expression in the osmosensitive areas in rat brain and facilitates water intake (2010)
  • Author(s): Otsubo, H.et al.
  • Journal Title: Peptides (in press)
  • Peer Reviewed
• [Journal Article] Robust upregulation of nuclear red fluorescent-tagged Fos marks neuronal activation in green fluorescent vasopressin neurons after osmotic stimulation in a double transgenic rat. (2009)
  • Author(s): Fujihara, H., Ueta, Y., Suzuki, H., Katoh, A., Ohbuchi, T., Otsubo, H., Dayanithi, G., Murphy, D.
  • Journal Title: Endocrinology 150(12) Pages: 5633-5638
  • Peer Reviewed
• [Journal Article] Ghrelin potentiates miniature excitatory postsynaptic currents in rat supraoptic magnocellular neurons. (2009)
  • Author(s): Yokoyama, T., Saito, T., Ohbuchi, T., Suzuki, H., Otsubo, H., Okamoto, T., Fujihara, H., Nagatomo, T., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology(Cover article of the issue) 21(11) Pages: 183-190
  • Peer Reviewed
• [Journal Article] Exaggerated response of a vasopressin-enhanced green fluorescent protein transgene to nociceptive stimulation in the rat. (2009)
  • Author(s): Suzuki, H., Kawasaki, M., Ohnishi, H., Otsubo, H., Ohbuchi, T., Katoh, A., Hashimoto, H., Yokoyama, T., Fujihara, H., Dayanithi, G., Murphy, D., Nakamura, T., Ueta, Y.
  • Journal Title: Journal of Neuroscience 29(42) Pages: 13182-13189
  • Peer Reviewed
• [Journal Article] Response of arginine vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamus of adjuvant-induced arthritic rats. (2009)
  • Author(s): Suzuki, H., Onaka, T., Kasai, M., Kawasaki, M., Ohnishi, H., Otsubo, H., Saito, T., Hashimoto, H., Yokoyama, T., Fujihara, H., Dayanithi, G., Murphy, D., Nakamura, T., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 21(3) Pages: 183-190
  • Peer Reviewed
• [Journal Article] Brain-derived neurotrophic factor inhibits spontaneous inhibitory postsynaptic currents in the rat supraoptic nucleus. (2009)
  • Author(s): Ohbuchi, T., Yokoyama, T., Saito, T., Hashimoto, H., Suzuki, H., Otsubo, H., Fujihara, H., Suzuki, H., Ueta, Y.
  • Journal Title: Brain Research 1258(3) Pages: 34-42
  • Peer Reviewed
• [Journal Article] Brain-derived neurotrophic factor inhibits spontaneous inhibitory postsynaptic currents in the rat supraoptic nucleus (2009)
  • Author(s): Ohbuchi, T.et al.
  • Journal Title: Brain Research 1258(3) Pages: 34-42
  • Peer Reviewed
• [Journal Article] Response of arginine vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamus of adjuvant-induced arthritic rats (2009)
  • Author(s): Suzuki, H.et al.
  • Journal Title: Journal of Neuroendocrinology 21(3) Pages: 183-190
  • Peer Reviewed
• [Journal Article] Centrally administered adrenomedullin 5 activates oxytocin-secreting neurons in the hypothalamus and elevates plasma oxytocin level in rats (2009)
  • Author(s): Otsubo H.et al.
  • Journal Title: Journal of Endocrinology 202(2) Pages: 237-247
  • Peer Reviewed
• [Journal Article] Regulatory mechanism of the arginine vasopressin-enhanced green fluorescent protein fusion gene expression in acute and chronic stress (2009)
  • Author(s): Suzuki, H.et al.
  • Journal Title: Peptides(Review) 30(9) Pages: 1763-1770
  • Peer Reviewed
• [Journal Article] Exaggerated response of a vasopressin-enhanced green fluorescent protein transgene to nociceptive stimulation in the rat (2009)
  • Author(s): Suzuki, H.et al.
  • Journal Title: Journal of Neuroscience 29(42) Pages: 13182-13189
  • Peer Reviewed
• [Journal Article] Ghrelin potentiates miniature excitatory postsynaptic currents in rat supraoptic magnocellular neurons (2009)
  • Author(s): 横山徹 et al.
  • Journal Title: Journal of Neuroendocrinology 21(11) Pages: 183-190
  • Peer Reviewed
• [Journal Article] Robust up-regulation of nuclear red fluorescent-tagged Fos marks neuronal activation in green fluorescent vasopressin neurons after osmotic stimulation in a double transgenic rat (2009)
  • Author(s): Fujihara, H.et al.
  • Journal Title: Endocrinology 150(12) Pages: 5633-5638
  • Peer Reviewed
• [Journal Article] TRPチャネルと浸透圧センシング (2009)
  • Author(s): 横山徹 et al.
  • Journal Title: 比較内分泌学 35(132) Pages: 23-28
  • NAID: 10024022482
• [Journal Article] 中枢性浸透圧調節とTRPチャネル (2009)
  • Author(s): 上田陽一 et al.
  • Journal Title: 自律神経 46(3) Pages: 186-189
  • NAID: 10025571080
• [Journal Article] Response of arginine vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamus of adjuvant-induced arthritic rats (2009)
  • Author(s): Suzuki, H. Onaka, T. Kasai, M. Kawasaki, M. Ohnishi, H. Otsubo, H. Saito, T. Hashimoto, H. Yokoyama, T. Fujihara, H. Dayanithi, G. Murphy, D. Nakamura, T. & Ueta Y.
  • Journal Title: Journal of Neuroendocrinology 21(3) Pages: 183-190
  • Peer Reviewed
• [Journal Article] Brain - derived neurotrophic factor inhibits spontaneous inhibitory postsynaptic currents in the rat supraoptic nucleus (2009)
  • Author(s): Ohbuchi, T. Yokoyama, T. Saito, T. Hashimoto, H. Suzuki, H. Otsubo, H. Fujihara, H. Suzuki, H. & Ueta, Y.
  • Journal Title: Brain Research 1258 Pages: 34-42
  • Peer Reviewed
• [Journal Article] Chronic osmotic stimuli increase salusin-β-like immunoreactivity in the rat hypothalamo-neurohypophyseal system : possible involvement of salusin-β on [Ca^<2+>]_i increase and neurohypophyseal hormone release from the axon terminals. (2008)
  • Author(s): Saito, T., Dayanithi, G., Saito, J., Onaka, T., Urabe, T., Watanabe, TX., Hashimoto, H., Yokoyama, T., Fujihara, H., Yokota, A., Nishizawa, S., Hirata, Y., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 20(2) Pages: 207-219
  • Peer Reviewed
• [Journal Article] Chronic osmotic stimuli increase salusin-β-like immunoreactivity in the rat hypothalamo-neurohypophyseal system : possible involvement of salusin- on [Ca2+]i increase and neurohypophyseal hormone release from the axon terminals (2008)
  • Author(s): Saito, T. Dayanithi, G. Saito, J. Onaka, T. Urabe, T. Watanabe, TX. Hashimoto, H. Yokoyama, T. Fujihara, H. Yokota, A. Nishizawa, S. Hirata, Y. & Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 20(2) Pages: 207-219
  • Peer Reviewed
• [Journal Article] The effects of apelin on the electrical activity of hypothalamic magnocellular vasopressin and oxytocin neurons and somato/dendritic peptide release. (2008)
  • Author(s): Tobin, A.V. Bull, P.M. Arunachalam, S. O'Carroll, A.-M. Ueta, Y. & Ludwig, M.
  • Journal Title: Endocrinology 149(12) Pages: 6136-6145
  • Peer Reviewed
• [Journal Article] Chronic osmotic stimuli increase salusin-β-like immunororeactivity in the rat hypothalamo-neurohypophyseal system : possible involvement of salusin-β on[Ca^<2+>]i increase and neurbhypophyseal hormone release from the axon terminals (2008)
  • Author(s): Saito, T. Dayanithi, G. Saito, J. Onaka, T. Urabe, T. Watanabe, TX. Hashimoto, H. Yokoyama., T. Fujihara, H. Yokota, A. Nishizawa, S. Hirata, Y. & Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 20(2) Pages: 207-219
  • Peer Reviewed
• [Journal Article] Adrenomedullin 2/intermedin-like immunoreactivity in the hypothalamus and brainstem of rats (2008)
  • Author(s): Hashimoto, H. Kitamura, K. Kawasaki, M. Saito, T. Suzuki, H. Otsubo, H. Ohbuchi, T. Yokoyama, T. Fujihara, H. Takei, Y. & Ueta. Y.
  • Journal Title: Autonomic Neuroscience : Basic and Clinical 139(1-2) Pages: 46-54
  • Peer Reviewed
• [Journal Article] Specific expression of optically active reporter gene in arginine vasopressin-secreting neurosecretory cells in the hypothalamic-neurohypophy seal system (2008)
  • Author(s): Ueta, Y. Fujihara, H. Dayanithi, G. Kawata, M. & Murphy, D.
  • Journal Title: Journal of Neuroendocrinology 20(6)(Review) Pages: 660-664
  • Peer Reviewed
• [Journal Article] The effects of apelin on the electrical activity of hypothalamic magnocellular vasopressin and oxytocin neurons and somato/dendritic peptide release (2008)
  • Author(s): Tobin, A. V. Bull, P. M. Arunachalam, S. O'Carroll, A.-M. Ueta, Y. & Ludwig, M.
  • Journal Title: Endocrinology 149(12) Pages: 6136-6145
  • Peer Reviewed
• [Journal Article] Adrenomedullin 2/ intermedin-like immunoreactivity in the hypothalamus and brainstem of rats. (2008)
  • Author(s): Hashimoto, H. Kitamura, K. Kawasaki, M. Saito, T. Suzuki, H. Otsubo, H. Ohbuchi, T. Yokoyama, T. Fujihara, H. Takei, Y. & Ueta, Y.
  • Journal Title: Autonomic Neuroscience: Basic and Clinical (In press)
  • Peer Reviewed
• [Journal Article] Chronic osmotic stimuli increase salusin-beta-like immunoreactivity in the rathypothalamo-neurohypophyseal system: possible involvement of salusin-beta on[Ca(2+)](i) increase and neurohypophyseal hormone release from the axon terminals. (2008)
  • Author(s): Saito, T. Dayanithi, G. Saito, J. Onaka, T. Urabe, T. Watanabe, TX. hashimoto, H. Yokoyama, T. Fujihara, H. Yokota, A. Nishizawa, S. Hirata, Y. & Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 209(2) Pages: 207-219
  • Peer Reviewed
• [Journal Article] Induction of the galanin-like peptide gene expression in the posterior pituitary gland after acute osmotic stimulus in rats. (2007)
  • Author(s): Kawasaki, M., Saito, J., Hashimoto, H., Suzuki, H., Otsubo, H., Fujihara, H., Ohnishi, H., Nakamura, T., Ueta, Y.
  • Journal Title: Neuroscience Letters 419(2) Pages: 125-130
  • Peer Reviewed
• [Journal Article] Centrally and peripherally administered ghrelin potently inhibits water intake in rats. (2007)
  • Author(s): Hashimoto, H., Fujihara, H., Kawasaki, M., Saito, T., Shibata, M., Otsubo, H., Takei, Y., Ueta, Y.
  • Journal Title: Endocrinology 148(4) Pages: 1638-1647
  • Peer Reviewed
• [Journal Article] Physiological studies of stress responses in the hypothalamus of vasopressin-enhanced green fluorescent protein transgenic rat. (2007)
  • Author(s): Shibata, M., Fujjihara, H., Suzuki, H., Ozawa, H., Kawata, M., Dayanithi, G., Murphy, D., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 19(4) Pages: 285-292
  • Peer Reviewed
• [Journal Article] Effects of the short chain sugar Acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthritic rats (2007)
  • Author(s): Kawasaki M, Onaka T, Saito J, Hashimoto H, Suzuki H, Otsubo H, Fujihara H, Okimoto N, Ohnishi H, Nakamura T, Ueta Y.
  • Journal Title: Journal of Neuroendocrinology 19(1) Pages: 54-65
  • Peer Reviewed
• [Journal Article] Centrally and peripherally administered ghrelin potently inhibits water intake in rats. (2007)
  • Author(s): Hashimoto, H. Fujihara, H. Kawasaki, M. Saito, T. Shibata, M. Otsubo, H. Takei, Y. & Ueta, Y.
  • Journal Title: Endocrinology 148(4) Pages: 1638-1647
  • Peer Reviewed
• [Journal Article] Downregulation of prolactin-releasing peptide gene expression in the hypothalamus and brainstem of diabetic rats (2007)
  • Author(s): Mera, T. Fujihara, H. Saito, J. Kawasaki, M. Hashimoto, H. Saito, T. Shibata, M. Onaka, T. Tanaka, Y. Oka, T. Tsuji, S. Ueta, Y.
  • Journal Title: Peptides 28(8) Pages: 1596-1604
  • Peer Reviewed
• [Journal Article] Induction of the galanin-like peptide gene expression in the posterior pituitary gland after acute osmotic stimulus in rats. (2007)
  • Author(s): Kawasaki, M. Saito, J. Hashimoto, H. Suzuki, H. Otsubo, H. Fujihara, H. Ohnishi, H. Nakamura, T. & Ueta, Y.
  • Journal Title: Neuroscience Letters 419(2) Pages: 125-130
  • Peer Reviewed
• [Journal Article] Adrenomedullin 2 (AM2)/intermedin is a more potent activator of hypothalamic oxytocin-secreting neurons than AM possibly through an unidentified receptor in rats. (2007)
  • Author(s): Hashimoto, H. Hyodo, S. Kawasaki, M. Otsubo, H. Yokoyama, T. Fujihara, H. Higuchi, T. Takei, Y. & Ueta, Y.
  • Journal Title: Peptides 28(5) Pages: 1104-1112
  • Peer Reviewed
• [Journal Article] Centrally and peripherally administered ghrelin potently inhibits water intake in rats. (2007)
  • Author(s): Hashimoto, H. Fujihara, H. Kawasaki, M. Saito, T. shibata, M. Otsubo, H. Takei, Y. & Ueta, Y.
  • Journal Title: Endocrinology 148(4) Pages: 1638-1647
  • Peer Reviewed
• [Journal Article] Physiological studies of stress responses in the hypothalamus of vasopressin-enhanced green fluorescent protein transgenic rat. (2007)
  • Author(s): Shibata, M. Fujjihara, H. Suzuki, H. Ozawa, H. Kawata, M. Dayanithi, G, Murphy, D. & Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 19(4) Pages: 285-292
  • Peer Reviewed
• [Journal Article] Effects of the short chain sugar acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthriticrats. (2007)
  • Author(s): Kawasaki, M. Onaka, T. Saito, J. Hashimoto, H. Suzuki, H. Otsubo, H. Fujihara, h. Okimoto, N. Ohnishi, H. Nakamura, T. & Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 19(10 Pages: 54-65
  • Peer Reviewed
• [Journal Article] アンジオテンシンIIによる後シナプス性自発電流の増強 (2007)
  • Author(s): 横山 徹、尾崎 由美、上田 陽
  • Journal Title: 生体の科学(医学書院) Pages: 224-229
• [Journal Article] GALPとその作用 (2007)
  • Author(s): 藤原 広明、上田 陽一
  • Journal Title: 内分泌・糖尿病科(科学評論社) Pages: 94-100
• [Journal Article] Exaggerated response of arginine vasopressin-enhanced green fluorescent protein fusion gene to salt loading without disturbance of body fluid homeostasis in rats. (2006)
  • Author(s): Fujio, T., Fujihara, H., Shibata, M., Yamada, S., Onaka, T., Tanaka, K., Morita, H., Dayanithi, G., Kawata, M., Murphy, D., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology(Cover article of the issue) 18(10) Pages: 776-785
  • Peer Reviewed
• [Journal Article] The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats (2006)
  • Author(s): Kawasaki, M., Yamaga, C., Onaka, T., Saito, J., Mera, T., Hashimoto, H., Fujihara, H., Okimoto, N., Ohnishi, H., Nakamura, T., Ueta, Y.
  • Journal Title: Brain Research 1086(1) Pages: 133-141
• [Journal Article] Centrally administered neuropeptide W-30 activates magnocellular neurosecretory cells in the supraoptic and paraventricular nuclei with neurosecretion in rats (2006)
  • Author(s): Kawasaki, M., Onaka, T., Nakazato, M., Saito, J., Mera, T., Hashimoto, H., Fujihara, H., Okimoto, N., Ohnishi, H., Nakamura, T., Ueta, Y.
  • Journal Title: Journal of Endocrinology 190(2) Pages: 213-223
• [Journal Article] Exaggerated response of arginine vasopressin-enhanced green fluorescent protein fusion gene to salt loading without disturbance of body fluid homeostasis in rats (2006)
  • Author(s): Fujio, T., Fujihara, H., Shibata, M., Yamada, S., Onaka, T., Tanaka, K., Morita, H., Dayanithi, G., Kawata, M., Murphy, D., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 18(10) Pages: 776-785
• [Journal Article] Effects of the short chain sugar acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthritic rats (2006)
  • Author(s): Kawasaki, M., Onaka, T., Saito, J., Hashimoto, H., Suzuki, H., Otsubo, H., Fujihara, H., Okimoto, N., Ohnishi, H., Nakamura, T., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 19(1) Pages: 54-65
• [Journal Article] Physiological studies of stress responses in the hypothalamus of vasopressin-enhanced green fluorescent protein transaenic rat (2006)
  • Author(s): Shibata, M., Fujjihara, H., Suzuki, H., Ozawa, H., Kawata, M., Dayanithi, G., Murphy, D., Ueta, Y.
  • Journal Title: Journal of Neuroendocrinology 19(4) Pages: 285-292
• [Journal Article] Centrally and peripherally administered ghrelin potently inhibits water intake in rats (2006)
  • Author(s): Hashimoto, H., Fujihara, H., Kawasaki, M., Saito, T., Shibata, M., Otsubo, H., Takei, Y., Ueta, Y.
  • Journal Title: Endocrinology 148(4) Pages: 1638-1647
• [Presentation] 浸透圧センシングとバゾプレッシン分泌 (2010)
  • Author(s): 上田陽一
  • Organizer: 特定領域研究公開シンポジウム「細胞感覚:セルセンサーのモーダルシフト」
  • Place of Presentation: 東京
  • Year and Date: 2010-12-23
• [Presentation] Relaxin-3のラット脳室内投与による Fos 蛋白の脳内発現分布および飲水行動への影響 (2010)
  • Author(s): 大坪広樹
  • Organizer: 第20回バゾプレシン研究会
  • Place of Presentation: 慶應義塾大学病院(東京)
  • Year and Date: 2010-01-09
• [Presentation] Regulation of stress responses by peptides : New transgenic animal models. (2010)
  • Author(s): Ueta, Y.
  • Organizer: The 7^<th> International Congress of Neuroendocrinology symposium
  • Place of Presentation: Rouen, France
• [Presentation] The expression of the vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamo-pituitary system in rats : a new aspect of vasopressin dynamics. (2010)
  • Author(s): Ueta Y., Fujihara, H., Murphy, D.
  • Organizer: 14^<th> International Congress of Endocrinology
  • Place of Presentation: Kyoto, Japan
• [Presentation] Regulation of stress responses by peptides : New transgenic animal models. (2010)
  • Author(s): Ueta, Y.
  • Organizer: The 7^<th> International Congress of Neuroendocrinology symposium
  • Place of Presentation: Law Faculty, Rouen, France
• [Presentation] Physiological roles of vasopressin in the extra-hypothalamic areas. (2010)
  • Author(s): Hashimoto, H.Ludwig, M.Leng, G., Ueta, Y.
  • Organizer: The 9^<th> Korea-Japan Joint Symposium on Physiology
  • Place of Presentation: Keitenkaku, Kagoshima, Japan
• [Presentation] Diurnal changes of arginine vasopressin-enhanced green fluorescent protein fusion transgene expression in the rat suprachiasmatic nucleus. (2010)
  • Author(s): Maruyama, T.Ohbuchi, T.Fjihara, H.Shibata, M.Murphy, D.Dayanithi, G., Ueta, Y.
  • Organizer: 5^<th> International Peptide Symposium
  • Place of Presentation: Kyoto International Conference Center, Kyoto, Japan
• [Presentation] ラットバゾプレッシン産生ニューロンにおけるBKチャネルについての検討 (2010)
  • Author(s): 大淵豊明
  • Organizer: 第20回日本病態生理学会大会
  • Place of Presentation: 奈良県立医科大学厳橿会館(奈良)
• [Presentation] Relaxin-3のラット脳室内投与による Fos 蛋白の脳内発現分布および飲水行動への影響 (2010)
  • Author(s): 大坪広樹
  • Organizer: 第20回日本病態生理学会大会
  • Place of Presentation: 奈良県立医科大学厳橿会館(奈良)
• [Presentation] バゾプレッシン(AVP)-eGFPトランスジェニックラットにおける青斑核での特異的なAVP-eGFPの合成 (2010)
  • Author(s): 轟美和子
  • Organizer: 第20回日本病態生理学会大会
  • Place of Presentation: 奈良県立医科大学厳橿会館(奈良)
• [Presentation] c-fos-RFPとAVP-eGFPのダブルトランスジェニックラットの作出と浸透圧刺激に対する反応 (2010)
  • Author(s): 藤原広明
  • Organizer: 第20回日本病態生理学会大会
  • Place of Presentation: 奈良県立医科大学厳橿会館(奈良)
• [Presentation] 視索上核大細胞性神経分泌ニューロンへの興奮性シナプス入力に対するグレリンの効果はTRPV1によって調節される (2010)
  • Author(s): 横山徹
  • Organizer: 第20回日本病態生理学会大会
  • Place of Presentation: 奈良県立医科大学厳橿会館(奈良)
• [Presentation] The expression of the vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamo-pituitary system in rats : a new aspect of vasopressin dynamics (2010)
  • Author(s): 上田陽一
  • Organizer: 14^<th> International Congress of Endocrinology
  • Place of Presentation: Kyoto International Conference Center(Kyoto, Japan)
• [Presentation] TRPV1は視索上核大細胞性神経分泌ニューロンにおいて浸透圧・アンジオテシンIIの興奮性シナプス入力の調節に関与している (2009)
  • Author(s): 横山徹
  • Organizer: 第10回 Neurocardiology Workshop
  • Place of Presentation: 東京ステーションコンファレンス(東京)
  • Year and Date: 2009-07-25
• [Presentation] ラットバゾプレッシン産生ニューロンにおける Large-conductance calcium activated potassium channels(BKチャンネル)についての検討 (2009)
  • Author(s): 大淵豊明
  • Organizer: 九州脳と高血圧研究会
  • Place of Presentation: JALリゾートシーホークホテル福岡(福岡)
  • Year and Date: 2009-07-18
• [Presentation] TRPチャンネルから視た神経分泌ニューロンの物理・化学感受性 (2009)
  • Author(s): 上田陽一、横山徹
  • Organizer: 第39回日本臨床神経生理学会学術大会シンポジウム
  • Place of Presentation: 北九州
• [Presentation] 多色蛍光タンパクを発現するトランスジェニックラットの作出と浸透圧刺激に対する反応 (2009)
  • Author(s): 藤原広明、鈴木仁士、加藤明子、大坪広樹、上田陽一
  • Organizer: 第50回日本組織細胞化学会
  • Place of Presentation: 滋賀
• [Presentation] 視索上核大細胞性神経分泌細胞の浸透圧感受性におけるTRPV1の関与 (2009)
  • Author(s): 横山徹、大淵豊明、藤原広明、長友敏寿、上田陽一
  • Organizer: 第32回日本神経科学大会
  • Place of Presentation: 名古屋
• [Presentation] Relaxin-3の中枢性生理作用についての検討 (2009)
  • Author(s): 大坪広樹
  • Organizer: 第82回日本内分泌学会学術総会
  • Place of Presentation: 群馬県民会館(群馬)
• [Presentation] ラットバゾプレッシン産生ニューロンにおける酸感受性について (2009)
  • Author(s): 大淵豊明
  • Organizer: 第82回日本内分泌学会学術総会
  • Place of Presentation: 群馬県民会館(群馬)
• [Presentation] オキシトシン-eCFPトランスジェニックラットへの浸透圧負荷の検討 (2009)
  • Author(s): 加藤明子
  • Organizer: 第82回日本内分泌学会学術総会
  • Place of Presentation: 群馬県民会館(群馬)
• [Presentation] Acid-Sensing Ion Channels in Vasopressin-Secreting Neurons of The Rat Supraoptic Nucleus (2009)
  • Author(s): 大淵豊明
  • Organizer: 36^<th> International Congress of Physiological Sciences
  • Place of Presentation: Kyoto International Conference Center(Kyoto, Japan)
• [Presentation] The Autocrine Role of Arginine-Vasopressin Released from Osmosensory Neurons Under Hypoosmotic Conditions (2009)
  • Author(s): Sato, K.
  • Organizer: 36^<th> International Congress of Physiological Sciences
  • Place of Presentation: Kyoto International Conference Center(Kyoto, Japan)
• [Presentation] Distribution Of Fos-Like Immunoreactivity in the Brain and Drinking Behavior after Centrally Administered Relaxin-3 in Rats (2009)
  • Author(s): 大坪広樹
  • Organizer: 36^<th> International Congress of Physiological Sciences
  • Place of Presentation: Kyoto International Conference Center(Kyoto, Japan)
• [Presentation] Green Fluorescent Vasopressin Neurons Express Nuclear Red Fluorescence after Osmotic Stimulation in a Double Transgenic Rat (2009)
  • Author(s): 藤原広明
  • Organizer: 2^<nd> School of Neuroendocrinology 2009
  • Place of Presentation: Hotel San-sui Kan(Ohita, Japan)
• [Presentation] Specific Expression of the Oxytocin-enhanced Cyan Fluorescent Protein Fusion Transgene in the Rat Hypothalamus and Posterior Pituitary (2009)
  • Author(s): 加藤明子
  • Organizer: 2^<nd> School of Neuroendocrinology 2009
  • Place of Presentation: Hotel San-sui Kan(Ohita, Japan)
• [Presentation] Physiological Role of Acid-sensing Ion Channels in the Identified Rat Hypothalamic Vasopressin Neurons of the Supraoptic Nucleus (2009)
  • Author(s): 大淵豊明
  • Organizer: 2^<nd> School of Neuroendocrinology 2009
  • Place of Presentation: Hotel San-sui Kan(Ohita, Japan)
• [Presentation] Distribution of Fos-like Immunoreactivity in the Brain and Drinking Behavior after Centrally Administered Relaxin-3 in Rats (2009)
  • Author(s): 大坪広樹
  • Organizer: 2^<nd> School of Neuroendocrinology 2009
  • Place of Presentation: Hotel San-sui Kan(Ohita, Japan)
• [Presentation] Nociceptive Stimulation Causes Exaggerated Response of Arginine Vasopressin-enhanced Green Fluorescent Protein Gene Expression in Rats (2009)
  • Author(s): 鈴木仁士
  • Organizer: 2^<nd> School of Neuroendocrinology 2009
  • Place of Presentation: Hotel San-sui Kan(Ohita, Japan)
• [Presentation] Induction of the Arginine Vasopressin-enhanced Green Fluorescent Protein Fusion Gene in the Rat Locus Coeruleus (2009)
  • Author(s): 轟美和子
  • Organizer: 2^<nd> School of Neuroendocrinology 2009
  • Place of Presentation: Hotel San-sui Kan(Ohita, Japan)
• [Presentation] TRPV1 Gene Deficiency Attenuates Miniature EPSCs Potentiation Induced by Mannitol and Angiotensin 11 in Supraoptic Magnocellular Neurons (2009)
  • Author(s): 横山徹
  • Organizer: 2^<nd> School of Neuroendocrinology 2009
  • Place of Presentation: Hotel San-sui Kan(Ohita, Japan)
• [Presentation] 下垂体後葉ホルモン研究における蛍光タンパクの応用:トランスジェニックラットによる浸透圧負荷の検討 (2009)
  • Author(s): 加藤明子
  • Organizer: 第36回日本神経内分泌学会
  • Place of Presentation: 北九州国際会議場(北九州)
• [Presentation] 急性疼痛ストレスにおけるAVPの役割:バゾプレッシン(AVP)-eGFPトランスジェニックラットを用いた検討 (2009)
  • Author(s): 鈴木仁士
  • Organizer: 第36回日本神経内分泌学会
  • Place of Presentation: 北九州国際会議場(北九州)
• [Presentation] Specific Expression of the Oxytocin-enhanced Cyan Fluorescent Protein Fusion Transgene in the Rat Hypothalamus and Posterior Pituitary (2009)
  • Author(s): 加藤明子
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] Circadian Rhythm of Vasopressin-Enhanced Green Fluorescent Protein Fusion Gene Expression in the Rat Suprachiasmatic Nucleus (2009)
  • Author(s): Maruyama, T.
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] Physiological Role of Acid-sensing Ion Channels in the Identified Rat Hypothalamic Vasopressin Neurons of the Supraoptic Nucleus (2009)
  • Author(s): 大淵豊明
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] Nociceptive Stimulation Causes Exaggerated Response of Arginine Vasopressin-enhanced Green Fluorescent Protein Gene Expression in Rat S (2009)
  • Author(s): 鈴木仁士
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] Green Fluorescent Vasopressin Neurons Express Nuclear Red Fluorescence after Osmotic Stimulation in a Double Transgenic Rat (2009)
  • Author(s): 藤原広明
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] Induction of the Arginine Vasopressin-enhanced Green Fluorescent Protein Fusion Gene in the Rat Locus Coeruleus (2009)
  • Author(s): 轟美和子
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] Centrally administered adrenomedullin 5 activates oxytocin-secreting neurons in the hypothalamus and elevates plasma oxytocin level in rats (2009)
  • Author(s): 大坪広樹
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] TRPV1 Gene Deficiency Attenuates Miniature EPSCs Potentiation Induced by Mannitol and Angiotensin 11 in Supraoptic Magnocellular Neurons (2009)
  • Author(s): 横山徹
  • Organizer: VIIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Kitakyushu International Conference Center(Kitakyushu, Japan)
• [Presentation] 視索上核大細胞性神経分泌細胞の浸透圧感受性におけるTRPV1の関与 (2009)
  • Author(s): 横山徹
  • Organizer: 第32回日本神経科学大会
  • Place of Presentation: 名古屋国際会議場(名古屋)
• [Presentation] 下垂体後葉ホルモン研究における蛍光タンパクの応用:トランスジェニックラットによる検討 (2009)
  • Author(s): 加藤明子
  • Organizer: 第50回日本組織細胞化学会
  • Place of Presentation: ピアザ淡海(滋賀)
• [Presentation] 多色蛍光タンパクを発現するトランスジェニックラットの作出と浸透圧刺激に対する反応 (2009)
  • Author(s): 藤原広明
  • Organizer: 第50回日本組織細胞化学会
  • Place of Presentation: ピアザ淡海(滋賀)
• [Presentation] 新規ペプチドアドレノメデュリン5の中枢性生理作用の検討 (2009)
  • Author(s): 大坪広樹
  • Organizer: 第50回日本組織細胞化学会
  • Place of Presentation: ピアザ淡海(滋賀)
• [Presentation] バゾプレッシン(AVP)-eGFPトランスジェニックラットを用いた急性疼痛ストレスに対するAVPの役割の検討 (2009)
  • Author(s): 鈴木仁士
  • Organizer: 第50回日本組織細胞化学会
  • Place of Presentation: ピアザ淡海(滋賀)
• [Presentation] 神経分泌細胞の同定と神経活動のイメージング (2009)
  • Author(s): 上田陽一
  • Organizer: 第62回日本自律神経学会総会ワークショップ
  • Place of Presentation: ダイワロイネットホテル和歌山(和歌山)
• [Presentation] ラットバゾプレッシン産生ニューロンにおける Large-conductance calcium activated potassium channels(BKチャネル)についての検討 (2009)
  • Author(s): 大淵豊明
  • Organizer: 第60回西日本生理学会
  • Place of Presentation: 福岡県歯科医師会館(福岡)
• [Presentation] トランスジェニックラットを用いた下垂体後葉ホルモン研究 (2009)
  • Author(s): 加藤明子
  • Organizer: 第60回西日本生理学会
  • Place of Presentation: 福岡県歯科医師会館(福岡)
• [Presentation] TRPチャンネルから視た神経分泌ニューロンの物理・化学感受性 (2009)
  • Author(s): 上田陽一
  • Organizer: 第39回日本臨床神経生理学会学術大会シンポジウム
  • Place of Presentation: 北九州国際会議場(北九州)
• [Presentation] Ghrelin potentiates miniature excitatory postsynaptic currents in supraoptic magnocellular neurons (2009)
  • Author(s): 横山徹
  • Organizer: 2009 International Symposium on Ghrelin
  • Place of Presentation: Tokyo International Forum(Tokyo, Japan)
• [Presentation] バゾプレッシンニューロンと浸透圧調節:TRPの関与 (2009)
  • Author(s): 上田陽一
  • Organizer: 第7回北海道大学脳科学研究教育センターシンポジウム
  • Place of Presentation: 北海道大学学術交流会館(札幌)
• [Presentation] TRPA1はラット視索上核大細胞性神経分泌ニューロンへの興奮性シナプス入力を促進する (2008)
  • Author(s): 横山徹、大淵豊明、藤原広明、長友敏寿、上田陽一
  • Organizer: 第36回自律神経生理研究会
  • Place of Presentation: 東京
  • Year and Date: 2008-12-06
• [Presentation] ラットにおける中枢性体液調節:ストレス・ペプチド・浸透圧感受性 (2008)
  • Author(s): 上田陽一
  • Organizer: 第33回日本比較内分泌学会大会シンポジウム
  • Place of Presentation: 広島
  • Year and Date: 2008-12-05
• [Presentation] ラットにおける中枢性体液調節:ストレス・ペプチド・浸透圧感受性 (2008)
  • Author(s): 上田 陽一
  • Organizer: 第33回日本比較内分泌学会大会(シンポジウム)
  • Place of Presentation: 広島
  • Year and Date: 2008-12-05
• [Presentation] ラットにおける中枢性体液調節 : ストレス・ペプチド・浸透圧感受性 (2008)
  • Author(s): 上田陽一
  • Organizer: 第33回日本比較内分泌学会大会(シンポジウム)
  • Place of Presentation: 広島
  • Year and Date: 2008-12-05
• [Presentation] 中枢性浸透圧調節とTRPチャネル (2008)
  • Author(s): 上田陽一
  • Organizer: 第61回日本自律神経学会総会シンポジウム
  • Place of Presentation: 横浜
• [Presentation] ラット視索上核大細胞性神経分泌ニューロンへのシナプス入力におけるTRPA1の役割:電気生理学的検討 (2008)
  • Author(s): 横山徹、大淵豊明、藤原広明、長友敏寿、上田陽一
  • Organizer: 第35回日本神経内分泌学会
  • Place of Presentation: 東京
• [Presentation] 浸透圧センサーとバゾプレッシン分泌 (2008)
  • Author(s): 上田陽一
  • Organizer: 第26回内分泌代謝学サマーセミナー
  • Place of Presentation: 名古屋
• [Presentation] 神経分泌細胞における浸透圧およびペプチドセンシングメカニズム (2008)
  • Author(s): 上田陽一、横山徹
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
• [Presentation] TRPチャネルと中枢性浸透圧調節 (2008)
  • Author(s): 上田陽一
  • Organizer: 第81回日本内分泌学会学術総会シンポジウム
  • Place of Presentation: 青森
• [Presentation] ラット視索上核大細胞性神経分泌ニューロンへの興奮性シナプス入力に対するグレリンの効果 (2008)
  • Author(s): 横山徹、齋藤健、大淵豊明、橋本弘史、鈴木仁士、大坪広樹、藤原広明、長友敏寿、上田陽一
  • Organizer: 第85回日本生理学会大会
  • Place of Presentation: 東京
• [Presentation] 遺伝子改変動物による下垂体後葉ホルモン研究の新展開 (2008)
  • Author(s): 上田陽一
  • Organizer: 第85回日本生理学会大会シンポジウム
  • Place of Presentation: 東京
• [Presentation] ストレスにおけるラット視床下部-下垂体後葉系のバゾプレッシンeGFP融合遺伝子発現と病態生理学的意義 (2008)
  • Author(s): 上田陽一、鈴木仁士
  • Organizer: 第17回日本病態生理学会大会シンポジウム
  • Place of Presentation: 神戸
• [Presentation] 中枢性浸透圧調節とTRPチャネル (2008)
  • Author(s): 上田 陽一
  • Organizer: 第61回日本自律神経学会総会(シンポジウム)
  • Place of Presentation: 横浜
• [Presentation] TRPチャネルと中枢性浸透圧調節 (2008)
  • Author(s): 上田 陽一
  • Organizer: 第81回日本内分泌学会学術総会(シンポジウム)
  • Place of Presentation: 青森
• [Presentation] Effects of centrally administered ghrelin and TRPV4 agonist on drinking behavior in rats (2008)
  • Author(s): Ueta, Y. Hashimoto, H. & Takei, Y.
  • Organizer: ENDO 08(The Endocrine Society's 90th Annual Meeting)
  • Place of Presentation: San Francisco, U.S.A.
• [Presentation] Response of arginine vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamus of formalin-induced nociceptive stimulated rats (2008)
  • Author(s): Suzuki, H. Kawasaki, M. Ohnishi, H. Otsubo, H. Yokoyama, T. Fujihara, H. Dayanithi, G. Murphy, D. Nakamura, T. & Ueta. Y.
  • Organizer: The 3^<rd> Asian Pain Symposium
  • Place of Presentation: Fukuoka, Japan
• [Presentation] Pain sensor TRPV1 facilities excitatory synaptic inputs to the magnocellular neurons in the supraoptic nucleus of rat (2008)
  • Author(s): Yokoyama, T. Okamoto, T. Minami, K. & Ueta, Y.
  • Organizer: The 3^<rd> Asian Pain Symposium
  • Place of Presentation: Fukuoka, Japan
• [Presentation] Effects of formalin-induced nociceptive stimulation in the hypothalamus of arginine vasopressin-enhanced green fluorescent protein transgen is rats (2008)
  • Author(s): Suzuki, H. T. Yokoyama, T. Fujihara, H. & Ueta. Y.
  • Organizer: Society for Neuroscience Annual Meeting
  • Place of Presentation: Washington DC, USA
• [Presentation] ラット視索上核大細胞性神経分泌ニューロンへの興奮性シナプス入力に対するアンジオテンシンIIおよびグレリンの影響 (2008)
  • Author(s): 横山徹、齋藤健、大淵豊明、橋本弘史、鈴木仁士、大坪広樹、上田陽一
  • Organizer: 第81回日本内分泌学会学術総会
  • Place of Presentation: 青森
• [Presentation] ラットバゾプレッシン産生ニューロンにおける酸感受性についての電気生理学的検討 (2008)
  • Author(s): 大淵豊明、横山徹、齋藤健、上田陽一
  • Organizer: 第35回日本神経内分泌学会
  • Place of Presentation: 東京
• [Presentation] ラット視索上核大細胞性神経分泌ニューロンへのシナプス入力におけるTRPA1の役割 : 電気生理学的検討 (2008)
  • Author(s): 横山徹、大淵豊明、藤原広明、長友敏寿、上田陽一
  • Organizer: 第35回日本神経内分泌学会
  • Place of Presentation: 東京
• [Presentation] バゾプレッシン-eGFPトランスジェニックラットにおける青斑核ノルアドレナリンニューロンでの特異的なeGFP蛍光の発現 (2008)
  • Author(s): 轟美和子、大坪広樹、柴田美雅、藤原広明、David Murphy、永田頌史、上田陽一
  • Organizer: 第35回日本神経内分泌学会
  • Place of Presentation: 東京
• [Presentation] ラット視交叉上核におけるバゾプレッシン-eGFP融合 (2008)
  • Author(s): 丸山崇、藤原広明、柴田美雅、David Murphy、上田陽一
  • Organizer: 第35回日本神経内分泌学会
  • Place of Presentation: 東京
• [Presentation] サリューシンβの中枢性浸透圧調節への関与 (2007)
  • Author(s): 斎藤 健、渡邊 卓司、卜部 倫子、橋本 弘史、藤原 広明、横山 徹、尾仲 達史、平田 結喜雄、上田 陽一
  • Organizer: 第35回自律神経生理研究会
  • Place of Presentation: 東京
  • Year and Date: 2007-12-01
• [Presentation] ラット視索上核神経分泌ニューロンでの抑制性シナプス後電流における浸透圧感受性 (2007)
  • Author(s): 大淵 豊明、斎藤 健、横山 徹、鈴木 秀明、上田 陽一
  • Organizer: 第35回自律神経生理研究会
  • Place of Presentation: 東京
  • Year and Date: 2007-12-01
• [Presentation] バゾプレッシン-eGFPラットの視交叉上核におけるサーカディアンリズムと時差ぼけモデルの検討 (2007)
  • Author(s): 藤原 広明、丸山 崇、上田 陽一
  • Organizer: 第25回産業医科大学学会総会
  • Place of Presentation: 北九州
  • Year and Date: 2007-10-05
• [Presentation] GFP monitoring in vitro in the posterior pituitary of arginine vasopresssin-eGFP transgenic rat. (2007)
  • Author(s): Fujihara, H. Saito, T. Dayanithi, G. Yao, S. Murphy, D. Paton, J. & Ueta, Y.
  • Organizer: Satellite Symposium of the 5th Congress of the International Society for Autonomic Neuroscience(ISAN 2007)
  • Place of Presentation: Wakayama, Japan
  • Year and Date: 2007-10-03
• [Presentation] アジュバント関節炎におけるバゾプレッシン(AVP)の役割:AVP-eGFPトランスジェニックラットを用いた検討 (2007)
  • Author(s): 鈴木 仁人、尾仲 達史、笹井 聖仙、川崎 展、大西 英生、大坪 広樹、藤原 広明、Govindan Dayanithi、David Murphy、中村 利孝、上田 陽一
  • Organizer: 第7回目本内分泌学会九州地方会
  • Place of Presentation: 福岡
  • Year and Date: 2007-09-01
• [Presentation] TRPと浸透圧感受性 (2007)
  • Author(s): 横山 徹
  • Organizer: 第9回産業生理セミナー
  • Place of Presentation: 北九州
  • Year and Date: 2007-08-25
• [Presentation] ラットの中枢および末梢に投与したグレリンの飲水への影響 (2007)
  • Author(s): 橋本 弘史、藤原 広明、川崎 展、柴田 美雅、斎藤 健、大坪 広樹、竹井 祥郎、上田 陽
  • Organizer: 第3回環帯生理学プレコングレス
  • Place of Presentation: 大阪
  • Year and Date: 2007-03-19
• [Presentation] 上田 陽一バゾプレッシン(AVP)-eGFPトランスジェニックラットを用'いた視床下部におけるAVP-eGF発現変化の定量化:ストレス負荷時での検討 (2007)
  • Author(s): 柴田 美雅、藤原 広明、小澤 一史、河田 光博、Govindan Dayanithi、David Murphy
  • Organizer: 第17回バゾプレシン研究会
  • Place of Presentation: 東京
  • Year and Date: 2007-01-06
• [Presentation] バゾプレッシンとオキシトシン;ストレスと生殖の視点から (2007)
  • Author(s): 上田陽一
  • Organizer: 第100回日本繁殖生物学会大会、第12回日本生殖内分泌学会学術集会合同大会ジョイントシンポジウム
  • Place of Presentation: 東京
• [Presentation] The expression of the arginine vasopressin-enhanced green fluorescent protein fusion gene in the transgenic rat brain. (2007)
  • Author(s): Ueta, Y., Matsui, A., Fujihara, H., Sakamoto, F., Kawata, M., Dayanithi, G., Murphy, D.
  • Organizer: VIIth World Congress on Neurohypophysial Hormones
  • Place of Presentation: Regensburg, Germany
• [Presentation] Response of arginine-enhanced green fluorescent protein fusion gene in the hypothalamus of adjuvant-induced arthritic rats. (2007)
  • Author(s): Suzuki, H. Onaka, T. Kasai, M. Kawasaki, M. Ohnishi, H. Otsubo, H. Fujihara, H. Nakamura, T. Dayanithi, G. Murphy, D. & ueta, Y.
  • Organizer: Society for Neuroscience 36th Annual Meeting
  • Place of Presentation: San Diego, California
• [Presentation] Salusin-β evoked the neurohypophyseal hormone release from the neurohypophysis. (2007)
  • Author(s): Saito, T. Dayanithi, G. Watanabe, T.X. Urabe, T. Hashimoto, H. Suzuki, H. Yokoyama, T. Fujihara, H. Onaka, T. Hirata, Y. & Ueta, Y.
  • Organizer: Society for Neuroscience 36th Annual Meeting
  • Place of Presentation: San Diego, California
• [Presentation] Osmosensitivity in the synaptic inputs to the magnocellular neurosecretory cells in the supraoptic nucleus of rat. (2007)
  • Author(s): Yokoyama, T. Saito, T. Fujihara, H. & ueta, Y.
  • Organizer: Society for Neuroscience 36th Annual Meeting
  • Place of Presentation: San Diego, California
• [Presentation] Effects of acute light-phase advance on the gene expressions of galanin, arginine vasopressin-enhanced green fluorescent protein, Per 1 and Per 2 in the rat hyothalamus. (2007)
  • Author(s): Fujihara, H. Maruyama, T. Sei, H. Nishino, S. Dayanithi, G. Murphy, D. & Ueta, Y.
  • Organizer: Society for Neuroscience 36th Annual Meeting
  • Place of Presentation: San Diego, California
• [Presentation] ラット視床下部-下垂体後葉系におけるsalusin-β様免疫染色性の生理学的検討 (2007)
  • Author(s): 齋藤 健、渡邊 卓司、卜部 倫子、橋本 弘史、藤原 広明、大坪 広樹、横山 徹、平田 結 喜緒、上田 陽一
  • Organizer: 第17回日本病態生理学会大会
  • Place of Presentation: 沖縄
• [Presentation] 急性浸透圧刺激時のラット下垂体後葉におけるガラニン様ペプチド遺伝発現 (2007)
  • Author(s): 川崎 展、斎藤 淳、橋本 弘史、鈴木 仁士、大坪 広樹、藤原 広明、上田 陽一
  • Organizer: 第84回日本生理学会
  • Place of Presentation: 大阪
• [Presentation] サリューシンーβはラット下垂体後葉からの後葉ホルモン分泌を刺激する (2007)
  • Author(s): 斎藤 健、Govindan Dayanithi、渡邊 卓司、卜部 倫子、橋本 弘史、藤原 広明、尾仲 達史、平田 結喜緒、上田 陽一
  • Organizer: 第84回日本生理学会
  • Place of Presentation: 大阪
• [Presentation] バゾプレッシン-eGFPトランスジェニックラットの下垂体後葉におけるin Vitro eGFP蛍光連続測定の試み (2007)
  • Author(s): 藤原 広明、Yao Song、Paton Julian、上田 陽一
  • Organizer: 第84回日本生理学会
  • Place of Presentation: 大阪
• [Presentation] アドレノメデュリン2の神経内分泌系への作用のアドレノメデュリンとの比較 (2007)
  • Author(s): 橋本 弘史、兵藤 晋、川崎 展、斎藤 健、大坪 広樹、藤原 広明、樋口 隆、竹井 祥郎、上田 腸一
  • Organizer: 第84回日本生理学会
  • Place of Presentation: 大阪
• [Presentation] ラット視索上聴神経分泌ニューロンへのシナプス入力 (2007)
  • Author(s): 上田 陽一、横山 徹
  • Organizer: 第4回NEFRE
  • Place of Presentation: 千葉
• [Presentation] バゾプレッシンーeGFPトランスジェニックラットにおけるGFP発現細胞の脳内分布についての検討 (2007)
  • Author(s): 上田 陽一、松井 亜弓、藤原 広明、坂本 浩隆、河田 光博、Murphy David
  • Organizer: 第34回日本神経内分泌学会
  • Place of Presentation: 前橋
• [Presentation] ラット脳内におけるアドレノメデュリン2の局在と中枢性オキシトシン分泌作用における特異的受容体の検討 (2007)
  • Author(s): 橋本 弘史、兵藤 晋、藤原 広明、樋口 隆、北村 和雄、竹井 祥郎、上田 陽一
  • Organizer: 第34回日本神経内分泌学会
  • Place of Presentation: 前橋
• [Presentation] ラット視索上核大細胞性神経分泌細胞におけるシナプス入力の浸透圧感受性の検討 (2007)
  • Author(s): 横山 徹、斎藤 健、藤原 広明、上田 陽一
  • Organizer: 第30回目本神経科学大会
  • Place of Presentation: 横浜
• [Presentation] バゾプレッシン(AVP)-GFPトランスジェニックラットを用いたアジュバント関節炎におけるAVPの役割の検討 (2007)
  • Author(s): 鈴木 仁士、尾仲 達史、笹井 聖仙、川崎 展、大西 英生、藤原 広明、Covindan Dayanithi、David Murphy、中村 利孝、上田 陽一
  • Organizer: 第58回西日本生理学会
  • Place of Presentation: 福岡
• [Presentation] バゾプレッシンとオキシトシン;ストレスと生殖の視点から、第100回日本繁殖生物学会大会 (2007)
  • Author(s): 上田 陽一
  • Organizer: 第12回日本生殖内分泌学会学術集会合同大会
  • Place of Presentation: 東京
• [Presentation] ラット下垂体後葉系におけるサリューシンβの産生/局在と作用機序 (2007)
  • Author(s): 斎藤 健、渡邊 卓司、卜部 倫子、橋本 弘史、藤原 広明、横山 徹、尾仲 達史、平田 結喜雄、上田 陽一
  • Organizer: 第11回目本心血管内分泌代謝学会学術総会
  • Place of Presentation: 東京
• [Presentation] バゾプレッシンニューロン研究の今:遺伝子改変動物を用いた研究 (2006)
  • Author(s): 上田陽一
  • Organizer: 第16回神経科学の基礎と臨床
  • Place of Presentation: 大阪
  • Year and Date: 2006-12-16
• [Presentation] 新規循環関連ペプチドと下垂体後葉系 (2006)
  • Author(s): 上田陽一
  • Organizer: 第29回日本神経科学大会シンポジウム
  • Place of Presentation: 京都
• [Book] Central Mechanisms of Cardiovascular Regulation (2007)
  • Author(s): Ueta, Y. Fujihara, H. & Yokoyama, T.
  • Publisher: Transworld Research Network( Editors: Kubo, T. & Kuwaki, T.)
• [Book] 最新自律神経学 (2007)
  • Author(s): 上田 陽一
  • Publisher: 新興医学出版社(宇尾野公義・入来正や監修)
• [Remarks]
  • URL: http://www.nips.ac.jp/cellsensor/NL16.html
• [Remarks] ホームページ
  • URL: http://www.nips.ac.jp/cellsensor/NL_1_6.html