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Novel and Interdisciplinary Application of Hard X-ray and Gamma-ray Detectors

Planned Research

Project AreaToward new frontiers : Encounter and synergy of state-of-the-art astronomical detectors and exotic quantum beams
Project/Area Number 18H05463
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionThe University of Tokyo

Principal Investigator

Takahashi Tadayuki  東京大学, カブリ数物連携宇宙研究機構, 教授 (50183851)

Co-Investigator(Kenkyū-buntansha) 武田 伸一郎  東京大学, カブリ数物連携宇宙研究機構, 特任助教 (80553718)
織田 忠  東京大学, カブリ数物連携宇宙研究機構, 特任助教 (10746522)
柳下 淳  東京大学, カブリ数物連携宇宙研究機構, 特任助教 (20626676)
サンペトラ オルテア  慶應義塾大学, 医学部(信濃町), 講師 (50571113)
益子 高  近畿大学, 薬学部, 研究員 (30157200)
内山 泰伸  立教大学, 人工知能科学研究科, 教授 (00435801)
能町 正治  大阪大学, 核物理研究センター, 招へい教授 (90208299)
池田 博一  国立研究開発法人宇宙航空研究開発機構, 宇宙探査イノベーションハブ, 上席研究開発員 (10132680)
Project Period (FY) 2018-06-29 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥155,480,000 (Direct Cost: ¥119,600,000、Indirect Cost: ¥35,880,000)
Fiscal Year 2022: ¥27,040,000 (Direct Cost: ¥20,800,000、Indirect Cost: ¥6,240,000)
Fiscal Year 2021: ¥34,710,000 (Direct Cost: ¥26,700,000、Indirect Cost: ¥8,010,000)
Fiscal Year 2020: ¥38,220,000 (Direct Cost: ¥29,400,000、Indirect Cost: ¥8,820,000)
Fiscal Year 2019: ¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2018: ¥31,460,000 (Direct Cost: ¥24,200,000、Indirect Cost: ¥7,260,000)
Keywordsガンマ線検出器 / CdTe / 核医学 / SPECT / コンプトンカメラ / ガンマ線イメージング / 分子イメージング
Outline of Final Research Achievements

We developed a gamma-ray imager based on the requirements of our research projects and nuclear medicine. We applied the technology based on a high-resolution CdTe imager to in vivo imaging of cancer-bearing mice. We succeeded in simultaneously visualizing the accumulation of three different RI compounds in the microstructure of the mouse pharynx with high spatial resolution. For image analysis, the analytical technique of X-ray observation of supernova remnants was applied. A wide-field imager was developed to study in vivo pharmacokinetics and successfully visualize At-211 accumulation in tumors, which could not be determined with the conventional SPECT system. We also applied our technology to non-destructive element analysis and polarization measurement in atomic physics and nuclear physics.

Academic Significance and Societal Importance of the Research Achievements

本研究で示した複数の分子プローブを優れた空間分解能で同時に可視化できる能力は、ひとつの組織の中(腫瘍、脳のみならず様々な組織)で、異なる生理機能を可視化できる可能性につながるため極めて重要な成果である。世界に先駆けて開発した高いエネルギー分解能CdTe 半導体イメージャを用いたアスタチン-211の高精度イメージングは、従来装置では検出が難しい小動物の体内の微弱なRIの集積の画像化が可能とし。がんなどの放射線内用療法における薬物動態の可視化に発展することが期待され、社会的インパクトも極めて高い。Si/CdTeコンプトンカメラの偏光観測能力を生かした新たな原子物理学、原子核物理学実験が芽生えた。

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (131 results)

All 2023 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (13 results) Journal Article (44 results) (of which Int'l Joint Research: 23 results,  Peer Reviewed: 42 results,  Open Access: 30 results) Presentation (65 results) (of which Int'l Joint Research: 26 results,  Invited: 9 results) Book (1 results) Remarks (5 results) Patent(Industrial Property Rights) (3 results)

  • [Int'l Joint Research] University of Arizona/University of Minnesota/University of California, Berkeley(米国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Queensland University(オーストラリア)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Durham University(英国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Stockholm University(スウェーデン)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] University of California, Berkeley/University of Arizona/University of Minnesota(米国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] Queensland University(オーストラリア)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] University of Queensland(オーストラリア)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Univers of Arizona(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] University of Arizona(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Queensland(オーストラリア)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] CEA/Saclay DSM(フランス)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Arizona(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Queensland University(オーストラリア)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Strong Polarization of a J=1/2 -> 1/2 Transition Arising from Unexpectedly Large Quantum Interference2023

    • Author(s)
      N Nakamura, N Numadate, S Oishi, XM Tong, X Gao, D Kato, H Odaka, T Takahashi,Y Tsuzuki, Y Uchida, H. Watanabe, S Watanabe, and H Yoneda
    • Journal Title

      Physical Review Letters

      Volume: 130 Issue: 11 Pages: 113001-113001

    • DOI

      10.1103/physrevlett.130.113001

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Gamma-ray computed tomography system with a double-sided strip detector2023

    • Author(s)
      T. Fukuchi、S. Takeda、M. Katsuragawa、G. Yabu、S. Watanabe、T. Takahashi、Y. Watanabe
    • Journal Title

      Journal of Instrumentation

      Volume: 18 Issue: 01 Pages: P01030-P01030

    • DOI

      10.1088/1748-0221/18/01/p01030

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Wide-gap CdTe strip detectors for high-resolution imaging in hard X-rays2023

    • Author(s)
      Nagasawa Shunsaku、Minami Takahiro、Watanabe Shin、Takahashi Tadayuki
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

      Volume: 1050 Pages: 168175-168175

    • DOI

      10.1016/j.nima.2023.168175

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of Nondestructive Elemental Analysis System for Hayabusa2 Samples Using Muonic X-rays2023

    • Author(s)
      Osawa Takahito、Nagasawa Shunsaku、Ninomiya Kazuhiko、Takahashi Tadayuki、Nakamura Tomoki et al.
    • Journal Title

      ACS Earth and Space Chemistry

      Volume: 7 Issue: 4 Pages: 699-711

    • DOI

      10.1021/acsearthspacechem.2c00303

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] MAXI?J1820+070 X-ray spectral-timing reveals the nature of the accretion flow in black hole binaries2023

    • Author(s)
      Kawamura Tenyo、Done Chris、Axelsson Magnus、Takahashi Tadayuki
    • Journal Title

      Monthly Notices of the Royal Astronomical Society

      Volume: 519 Issue: 3 Pages: 4434-4453

    • DOI

      10.1093/mnras/stad014

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Formation and evolution of carbonaceous asteroid Ryugu: Direct evidence from returned samples2023

    • Author(s)
      Nakamura T.、Matsumoto M.、Amano K.、Enokido Y.、Zolensky M. E.、Mikouchi T.、Genda H.、Tanaka S.、Zolotov M. Y.、Kurosawa K. .. Yabuta H. ... et al.
    • Journal Title

      Science

      Volume: 379 Issue: 6634 Pages: 8671-8671

    • DOI

      10.1126/science.abn8671

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dual‐targeting therapy against HER3/MET in human colorectal cancers2023

    • Author(s)
      Yamasaki Akitaka、Miyake Rikuto、Hara Yuta、Okuno Hideki、Imaida Takuya、Okita Kouki、Okazaki Shogo、Akiyama Yasutoshi、Hirotani Kenji、Endo Yuichi、Masuko Kazue、Masuko Takashi、Tomioka Yoshihisa
    • Journal Title

      Cancer Medicine

      Volume: - Issue: 8 Pages: 9684-9696

    • DOI

      10.1002/cam4.5673

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] CD98 regulates the phosphorylation of HER2 and a bispecific anti‐HER2/CD98 antibody inhibits the growth signal of human breast cancer cells2023

    • Author(s)
      Yamasaki Akitaka、Maruyama‐Takahashi Kumiko、Nishida Kento、Okazaki Shogo、Okita Kouki、Akiyama Yasutoshi、Suzuki Hideaki、Endo Yuichi、Masuko Kazue、Masuko Takashi、Tomioka Yoshihisa
    • Journal Title

      Genes to Cells

      Volume: - Issue: 5 Pages: 374-382

    • DOI

      10.1111/gtc.13016

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Example-based explainable AI and its application for remote sensing image classification2023

    • Author(s)
      Ishikawa Shin-nosuke、Todo Masato、Taki Masato、Uchiyama Yasunobu、Matsunaga Kazunari、Lin Peihsuan、Ogihara Taiki、Yasui Masao
    • Journal Title

      International Journal of Applied Earth Observation and Geoinformation

      Volume: 118 Pages: 103215-103215

    • DOI

      10.1016/j.jag.2023.103215

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 宇宙観測技術の核医学における分子イメージングへの展開2023

    • Author(s)
      柳下 淳、桂 川 美穂、武田 伸一郎、高橋 忠幸
    • Journal Title

      Isotope News

      Volume: 785 Pages: 6-10

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Pure Tungsten Collimator Manufactured Using 3D Printing Technology for the Evaluation of <sup>211</sup>At Radionuclide Therapy2022

    • Author(s)
      Fujii Hirofumi、Ohnuki Kazunobu、Takeda Shin’ichiro、Katsuragawa Miho、Yagishita Atsushi、Yabu Goro、Watanabe Shin、Takahashi Tadayuki
    • Journal Title

      RADIOISOTOPES

      Volume: 71 Issue: 2 Pages: 141-151

    • DOI

      10.3769/radioisotopes.71.141

    • ISSN
      0033-8303, 1884-4111
    • Year and Date
      2022-07-15
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Simultaneous visualization of multiple radionuclides in vivo2022

    • Author(s)
      Atsushi Yagishita, Hideaki Matsumura, Tadashi Orita, Izumi O. Umeda, et al.,
    • Journal Title

      Nature biomedical engineering

      Volume: 2022 Issue: 5 Pages: 640-647

    • DOI

      10.1038/s41551-022-00866-6

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Polarization measurement of L-shell radiative recombination x rays from highly charged bismuth ions2022

    • Author(s)
      Numadate Naoki、Oishi Shimpei、Odaka Hirokazu、Priti、Sakurai Makoto、Takahashi Tadayuki、Tsuzuki Yutaka、Uchida Yuusuke、Watanabe Hirofumi、Watanabe Shin、Yoneda Hiroki、Nakamura Nobuyuki
    • Journal Title

      Physical Review A

      Volume: 105 Issue: 2

    • DOI

      10.1103/physreva.105.023109

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Non-destructive 3D imaging method using muonic X-rays and a CdTe double-sided strip detector2022

    • Author(s)
      Chiu I-Huan、Takeda Shin’ichiro、Kajino Meito、Shinohara Atsushi、Katsuragawa Miho、Nagasawa Shunsaku、Tomaru Ryota、Yabu Goro、Takahashi Tadayuki、Watanabe Shin、Takeshita Soshi、Miyake Yasuhiro、Ninomiya Kazuhiko
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 5261-5261

    • DOI

      10.1038/s41598-022-09137-5

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A full spectral-timing model to map the accretion flow in black hole binaries: the low/hard state of MAXI J1820+0702022

    • Author(s)
      Kawamura Tenyo、Axelsson Magnus、Done Chris、Takahashi Tadayuki
    • Journal Title

      Monthly Notices of the Royal Astronomical Society

      Volume: 511 Issue: 1 Pages: 536-552

    • DOI

      10.1093/mnras/stac045

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] On the Formation of Over-ionized Plasma in Evolved Supernova Remnants2022

    • Author(s)
      Katsuragawa Miho、Lee Shiu-Hang、Odaka Hirokazu、Bamba Aya、Matsumura Hideaki、Takahashi Tadayuki
    • Journal Title

      The Astrophysical Journal

      Volume: 938 Issue: 1 Pages: 23-23

    • DOI

      10.3847/1538-4357/ac8cf9

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Study of Time Evolution of Thermal and Nonthermal Emission from an M-class Solar Flare2022

    • Author(s)
      Nagasawa Shunsaku、Kawate Tomoko、Narukage Noriyuki、Takahashi Tadayuki、Caspi Amir、Woods Thomas N.
    • Journal Title

      The Astrophysical Journal

      Volume: 933 Issue: 2 Pages: 173-173

    • DOI

      10.3847/1538-4357/ac7532

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] In Vitro Tumor Cell-Binding Assay to Select High-Binding Antibody and Predict Therapy Response for Personalized 64Cu-Intraperitoneal Radioimmunotherapy against Peritoneal Dissemination of Pancreatic Cancer: A Feasibility Study2022

    • Author(s)
      Hihara Fukiko、Matsumoto Hiroki、Yoshimoto Mitsuyoshi、Masuko Takashi、Endo Yuichi、Igarashi Chika、Tachibana Tomoko、Shinada Mitsuhiro、Zhang Ming-Rong、Kurosawa Gene、Sugyo Aya、Tsuji Atsushi B.、Higashi Tatsuya、Kurihara Hiroaki、Ueno Makoto、Yoshii Yukie
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 10 Pages: 5807-5807

    • DOI

      10.3390/ijms23105807

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain2022

    • Author(s)
      Hasegawa Kana et al.
    • Journal Title

      Science Translational Medicine

      Volume: 14 Issue: 632 Pages: 7706-7706

    • DOI

      10.1126/scitranslmed.aax7706

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Analysis of Target Molecules towards Anti-cancer Therapeutic Antibodies2021

    • Author(s)
      Masuko Takashi
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 141 Issue: 1 Pages: 81-92

    • DOI

      10.1248/yakushi.20-00183

    • NAID

      130007964819

    • ISSN
      0031-6903, 1347-5231
    • Year and Date
      2021-01-01
    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Amino BODIPY-Based Blue Fluorescent Probes for Aldehyde Dehydrogenase 1-Expressing Cells2021

    • Author(s)
      Yagishita Atsushi、Ueno Tasuku、Tsuchihara Katsuya、Urano Yasuteru
    • Journal Title

      Bioconjugate Chemistry

      Volume: 32 Issue: 2 Pages: 234-238

    • DOI

      10.1021/acs.bioconjchem.0c00565

    • Related Report
      2021 Annual Research Report 2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Novel method for screening functional antibody with comprehensive analysis of its immunoliposome2021

    • Author(s)
      Hamamichi Shusei、Fukuhara Takeshi、Umeda Izumi O.、Fujii Hirofumi、Hattori Nobutaka
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41598-021-84043-w

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Consensus sequence among natural transmembrane linkers for single-polypeptide chain (sc) connection of two G-Protein-coupled receptors in tandeml2021

    • Author(s)
      T. Kamiya, T. Masuko, DS. Borroto-Escuela, H. Okado, H. Nakata
    • Journal Title

      J Mol Genetics, 2021

      Volume: 13 Pages: 1-45

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Lactate Reprograms Energy and Lipid Metabolism in Glucose-Deprived Oxidative Glioma Stem Cells2021

    • Author(s)
      Minami Noriaki、Tanaka Kazuhiro、Sasayama Takashi、Kohmura Eiji、Saya Hideyuki、Sampetrean Oltea
    • Journal Title

      Metabolites

      Volume: 11 Issue: 5 Pages: 325-325

    • DOI

      10.3390/metabo11050325

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target.2021

    • Author(s)
      Hayashi N, Yamasaki A, Ueda S, Okazaki S, Ohno Y, Tanaka T, Endo Y, Tomioka Y, Masuko K, Masuko T, Sugiura R.
    • Journal Title

      Oncotarget

      Volume: 12 Issue: 13 Pages: 1256-1270

    • DOI

      10.18632/oncotarget.27981

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Altered binding avidities and improved growth inhibitory effects of novel anti-HER3 mAb against human cancers in the presence of HER1-or HER2-targeted drugs2021

    • Author(s)
      Kouki Okita, Kazuki Imai, Kazunori Kato, Reiko Sugiura, Yuichi Endo, Kazue Masuko, Yoshihisa Tomioka, Takashi Masuko
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 576 Pages: 59-65

    • DOI

      10.1016/j.bbrc.2021.08.091

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Antitumor effects of novel mAbs against cationic amino acid transporter 1 (CAT1) on human CRC with amplified CAT1 gene2021

    • Author(s)
      Okita K, Hara Y, Okura H, Hayashi H, Sasaki Y, Masuko S, Kitadai E, Masuko K, Yoshimoto S, Hayashi N, Sugiura R, Endo Y, Okazaki S, Arai S, Yoshioka T, Matsumoto T, Makino Y, Komiyama H, Sakamoto K, Masuko T.
    • Journal Title

      Cancer Sci.

      Volume: 112 Issue: 2 Pages: 563-574

    • DOI

      10.1111/cas.14741

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Automatic Detection of Occulted Hard X-Ray Flares Using Deep-Learning Methods2021

    • Author(s)
      Ishikawa Shin-nosuke、Matsumura Hideaki、Uchiyama Yasunobu、Glesener Lindsay
    • Journal Title

      Solar Physics

      Volume: 296 Issue: 2 Pages: 39-39

    • DOI

      10.1007/s11207-021-01780-x

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Development of a low-noise front-end ASIC for CdTe detectors2020

    • Author(s)
      Kawamura Tenyo、Orita Tadashi、Takeda Shin’ichiro、Watanabe Shin、Ikeda Hirokazu、Takahashi Tadayuki
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

      Volume: 982 Pages: 164575-164575

    • DOI

      10.1016/j.nima.2020.164575

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imaging and spectral performance of a 60μm pitch CdTe Double-Sided Strip Detector2020

    • Author(s)
      Furukawa Kento、Nagasawa Shunsaku、Glesener Lindsay、Katsuragawa Miho、Takeda Shin’ichiro、Watanabe Shin、Takahashi Tadayuki
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

      Volume: 978 Pages: 164378-164378

    • DOI

      10.1016/j.nima.2020.164378

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Amplification of polarization correlations in Compton scattering of hard x-ray Bell states2020

    • Author(s)
      Caradonna Peter
    • Journal Title

      Journal of Physics Communications

      Volume: 4 Issue: 11 Pages: 115011-115011

    • DOI

      10.1088/2399-6528/abcb45

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] X-Ray Hotspots in the Northwest Shell of the Supernova Remnant RX J1713.7-39462020

    • Author(s)
      Higurashi Ryota、Tsuji Naomi、Uchiyama Yasunobu
    • Journal Title

      The Astrophysical Journal

      Volume: 899 Issue: 2 Pages: 102-102

    • DOI

      10.3847/1538-4357/ab9945

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anticancer agent synthesis designed by artificial intelligence: Pd(OAc)2-catalyzed one-pot preparation of biphenyls and its application to a concise synthesis of various diazofluorenes2020

    • Author(s)
      Takabatake Tetsuhiko、Tomita Hiroki、Okada Syo、Hayashi Natsumi、Masuko Takashi、Toyota Masahiro
    • Journal Title

      Tetrahedron Letters

      Volume: 61 Issue: 38 Pages: 152267-152267

    • DOI

      10.1016/j.tetlet.2020.152267

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Novel functional anti-HER3 monoclonal antibodies with potent anti- cancer effects on various human epithelial cancers.2020

    • Author(s)
      Okita K, Okazaki S, Uejima S, Yamada E, Kaminaka H, Kondo M, Ueda S, Tokiwa R, Iwata R, Yamasaki A, Hayashi N, Ogura D, Hirotani K, Yoshioka T, Inoue M, Masuko K, Masuko T
    • Journal Title

      Oncotarget

      Volume: 11 Issue: 1 Pages: 31-45

    • DOI

      10.18632/oncotarget.27414

    • NAID

      120006888520

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 高分解能SPECT装置を用いた中枢神経系リンパ管の 機能イメージング2020

    • Author(s)
      水間 広, 武田 伸一郎, 柳下 淳, 桂川 美穂, 大貫 和信
    • Journal Title

      Precision Medicine

      Volume: 3 Pages: 113-117

    • Related Report
      2020 Annual Research Report
  • [Journal Article] 高性能SPECTを用いた中枢神経系リンパ管の循環動態イメージングの開発2020

    • Author(s)
      水間 広, 武田 伸一郎, 柳下 淳, 桂川 美穂, 大貫 和信
    • Journal Title

      Medical Science Digest

      Volume: 46 Pages: 490-493

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Imaging of 99mTc-DMSA and 18F-FDG in humans using a Si/CdTe Compton camera2020

    • Author(s)
      Nakano Takashi、Sakai Makoto、Torikai Kota、Suzuki Yoshiyuki、Takeda Shin’ichiro、Noda Shin-ei、Yamaguchi Mitsutaka、Nagao Yuto、Kikuchi Mikiko、Odaka Hirokazu、Kamiya Tomihiro、Kawachi Naoki、Watanabe Shin、Arakawa Kazuo、Takahashi Tadayuki
    • Journal Title

      Physics in Medicine & Biology

      Volume: 65 Issue: 5 Pages: 05LT01-05LT01

    • DOI

      10.1088/1361-6560/ab33d8

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Probing entanglement in Compton interactions2019

    • Author(s)
      Caradonna Peter、Reutens David、Takahashi Tadayuki、Takeda Shin’ichiro、Vegh Viktor
    • Journal Title

      Journal of Physics Communications

      Volume: 3 Issue: 10 Pages: 105005-105005

    • DOI

      10.1088/2399-6528/ab45db

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development of 60 μm pitch CdTe double-sided strip detectors for the FOXSI-3 sounding rocket experiment2019

    • Author(s)
      Furukawa Kento、Buitrago-Casas Juan Camilo、Vievering Juliana、Hagino Kouichi、Glesener Lindsay、Athiray P.S.、Krucker S?m、Watanabe Shin、Takeda Shin’ichiro、Ishikawa Shin’nosuke、Musset Sophie、Christe Steven、Takahashi Tadayuki
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

      Volume: 924 Pages: 321-326

    • DOI

      10.1016/j.nima.2018.07.011

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The thermal-radiative wind in low-mass X-ray binary H1743-322: radiation hydrodynamic simulations2019

    • Author(s)
      Tomaru Ryota、Done Chris、Ohsuga Ken、Nomura Mariko、Takahashi Tadayuki
    • Journal Title

      Monthly Notices of the Royal Astronomical Society

      Volume: 490 Issue: 3 Pages: 3098-3111

    • DOI

      10.1093/mnras/stz2738

    • NAID

      120007132816

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] X-ray study of spatial structures in Tycho’s supernova remnant using unsupervised deep learning2019

    • Author(s)
      Iwasaki Hiroyoshi、Ichinohe Yuto、Uchiyama Yasunobu
    • Journal Title

      Monthly Notices of the Royal Astronomical Society

      Volume: 488 Issue: 3 Pages: 4106-4116

    • DOI

      10.1093/mnras/stz1990

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] NuSTAR Observations of the Supernova Remnant RX J1713.7?39462019

    • Author(s)
      Tsuji Naomi、Uchiyama Yasunobu、Aharonian Felix、Berge David、Higurashi Ryota、Krivonos Roman、Tanaka Takaaki
    • Journal Title

      The Astrophysical Journal

      Volume: 877 Issue: 2 Pages: 96-96

    • DOI

      10.3847/1538-4357/ab1b29

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Double photon emission coincidence imaging with GAGG-SiPM Compton camera2018

    • Author(s)
      Uenomachi Mizuki、Mizumachi Yuki、Yoshihara Yuri、Takahashi Hiroyuki、Shimazoe Kenji、Yabu Goro、Yoneda Hiroki、Watanabe Shin、Takeda Shin’ichiro、Orita Tadashi、Takahashi Tadayuki、Moriyama Fumiki、Sugawara Hirotaka
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

      Volume: 印刷中 Pages: 161682-161682

    • DOI

      10.1016/j.nima.2018.11.141

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inverse Compton emission from relativistic jets in binary systems2018

    • Author(s)
      Khangulyan, D, Bosch-Ramon, V, Uchiyama, Y.
    • Journal Title

      MNRAS

      Volume: 481 Issue: 2 Pages: 1455-1468

    • DOI

      10.1093/mnras/sty2356

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] AI-Powered Metaverse: Now and Future.2023

    • Author(s)
      Yasunobu Uchiyama
    • Organizer
      Interdisciplinary Science Conference in Okinawa (ISCO 2023)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Study of performance and response of thick CdTe double-sided strip detectors for various fields2023

    • Author(s)
      Takahiro Minami, Miho Katsuragawa, Shin’ichiro Takeda, Shin Watanabe, Yutaka Tsuzuki, Tadayuki Takahashi
    • Organizer
      Interdisciplinary Science Conference in Okinawa (ISCO 2023)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Wide-Gap CdTe Double-Sided Strip Detectors for High-Resolution Imaging Spectroscopy of Solar Flares in Hard X-rays2023

    • Author(s)
      Shunsaku Nagasawa, Takahiro Minami, Shin Watanabe, Tadayuki Takahashi
    • Organizer
      Interdisciplinary Science Conference in Okinawa (ISCO 2023)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Langevin Compton Imaging: a new Bayesian-based method to visualize gamma-ray sources2023

    • Author(s)
      Yutaka Tsuzuki, Shiro Ikeda, Hiroki Yoneda, Tadayuki Takahashi
    • Organizer
      Interdisciplinary Science Conference in Okinawa (ISCO 2023)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 太陽観測ロケット実験FOXSI-4に向けたワイドギャップCdTeストリップ検出器の開発と性能評価III2023

    • Author(s)
      長澤俊作, 南喬博, 高橋忠幸, 渡辺伸, 新井翔大 et al.
    • Organizer
      日本天文学会 2023年春季年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Successful encapsulation of 90Y/111In in liposomes and their potential as radio-theranostics agents,2022

    • Author(s)
      Izumi O. Umeda, Atsushi Yagishita, Miho Katsuragawa, Shin'ichiro Takeda, Motohiro Kojima, Hirohumi Fujii, Tadayuki Takahashi,
    • Organizer
      13th Congress of the World Federation of Nuclear Medicine and Biology
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a hard X-ray camera for pharmacokinetic study in small animals2022

    • Author(s)
      Miho Katsuragawa, Atsushi Yagishita, Shin'ichiro Takeda, Takahiro Minami, Kazunobu Ohnuki, Hirohumi Fujii, Tadayuki Takahashi
    • Organizer
      13th Congress of the World Federation of Nuclear Medicine and Biology
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ultra-high-resolution multi-isotope tomography with CdTe-DSD SPECT II2022

    • Author(s)
      Shin'ichiro Takeda, Tadashi Orita, Miho Katsuragawa, Goro Yabu, Ryota Tomaru, Atsushi Yagishita, Izumi O. Umeda, Tadayuki Takahashi, Shin Watanabe, Fumiki Moriyama, Hirotaka Sugawara, Yousuke Kanayama, Hiroshi Mizuma, Kazunobu Ohnuki, Hirofumi Fujii, Lars R. Furenlid
    • Organizer
      13th Congress of the World Federation of Nuclear Medicine and Biology
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Toward new Frontiers: Encounters and synergies with state-of-the-art astronomical X-ray detectors2022

    • Author(s)
      Tadayuki Takahashi
    • Organizer
      SPIE Optics+Photonics
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] NON-DESTRUCTIVE BULK ELEMENTAL ANALYSIS FOR STONES FROM ASTEROID RYUGU2022

    • Author(s)
      K. Ninomiya, T. Osawa, T. Takahashi, K. Terada et al.
    • Organizer
      The 53rd Lunar and Planetary Science Conference
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Imaging and Spectral Performance of Wide-gap CdTe Double-Sided Strip Detectors2022

    • Author(s)
      Shunsaku Nagasawa, Takahiro Minami, Shin Watanabe, Tadayuki Takahashi
    • Organizer
      9th Conference on New Developments in Photodetection (NDIP20)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a high-sensitivity CdTe semiconductor imager with a parallel-hole collimator2022

    • Author(s)
      Miho Katsuragawa, Atsushi Yagishita, Shin'ichiro Takeda, Takahiro Minami, Kazunobu Ohnuki, Hirohumi Fujii, Tadayuki Takahashi,
    • Organizer
      9th Conference on New Developments in Photodetection (NDIP20)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of an ultra-high-resolution multi-probe CdTe SPECT2022

    • Author(s)
      Shin'ichiro Takeda, Tadashi Orita, Miho Katsuragawa, Goro Yabu, Ryota Tomaru, Atsushi Yagishita, Izumi O. Umeda, Tadayuki Takahashi, Shin Watanabe, Fumiki Moriyama, Hirotaka Sugawara, Yousuke Kanayama, Hiroshi Mizuma, Kazunobu Ohnuki, Hirofumi Fujii, Lars R. Furenlid.
    • Organizer
      9th Conference on New Developments in Photodetection (NDIP20)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Application of a Si/CdTe Compton camera for the polarization measurement of radiative recombination x-rays2022

    • Author(s)
      Yutaka Tsuzuki, Shin Watanabe, Shimpei Oishi, Nobuyuki Nakamura, Naoki Numadate, Hirokazu Odaka, Yuusuke Uchida, Hiroki Yoneda, Tadayuki Takahashi
    • Organizer
      9th Conference on New Developments in Photodetection (NDIP20)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Successful encapsulation of 90Y in liposomes with high efficiency and their application to radionuclide therapy2022

    • Author(s)
      Izumi O. Umeda,Atsushi Yagishita, Miho katsuragawa,Yuniko Hamane, Motohiro Kojima, Hirohumi Fujii, Tadayuki Takahashi
    • Organizer
      The 81th Annual Meeting of the Japansee Cancer Association
    • Related Report
      2022 Annual Research Report
  • [Presentation] Development of an in vito imaging system with A parallel-hole collimator for pharmacokinetics study2022

    • Author(s)
      Miho Katsuragawa, Atsushi Yagishita, Izumi O. Umeda, Hirohumi Fujii, Tadayuki Takahashi
    • Organizer
      The 81th Annual Meeting of the Japansee Cancer Association
    • Related Report
      2022 Annual Research Report
  • [Presentation] Imaging and Spectral Performance of Wide-gap CdTe Double-Sided Strip Detectorsfor FOXSI-4 Sounding Rocket Experiment2022

    • Author(s)
      Shunsaku Nagasawa, Takahiro Minami, Shin Watanabe, Tadayuki Takahashi
    • Organizer
      The 4th Workshop on Quantum Beam Imaging (QBI2022)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] First demonstration of prompt gamma-ray imaging with a CdTe Compton camera2022

    • Author(s)
      Yutaka Tsuzuki,Takahito Osawa, Shin Watanabe, Hiroki Yoneda, Shunsaku Nagasawa, Tadayuki Takahashi
    • Organizer
      The 4th Workshop on Quantum Beam Imaging (QBI2022)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Study of performance and response of thick CdTe double-sided strip detector for various fields2022

    • Author(s)
      Takahiro Minami ,Miho Katsuragawa, Shunsaku Nagasawa, Shin’ichiro Takeda, Tadayuki Takahashi, Yutaka Tsuzuki, Shin Watanabe
    • Organizer
      The 4th Workshop on Quantum Beam Imaging (QBI2022)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of an ultra-high-resolution multi-probe CdTe SPECT2022

    • Author(s)
      Shin'ichiro Takeda, Tadashi Orita, Miho Katsuragawa, Goro Yabu, Ryota Tomaru, Atsushi Yagishita, Izumi O. Umeda, Tadayuki Takahashi, Shin Watanabe, Fumiki Moriyama, Hirotaka Sugawara, Yousuke Kanayama, Hiroshi Mizuma, Kazunobu Ohnuki, Hirofumi Fujii, Lars R. Furenlid
    • Organizer
      The 4th Workshop on Quantum Beam Imaging (QBI2022)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 硬X線・ガンマ線イメージング研究 at Kavli IPMU2022

    • Author(s)
      武田伸一郎, 織田忠, 柳下淳, 桂川美穂 他
    • Organizer
      第83回応用物理学会秋季学術講演会
    • Related Report
      2022 Annual Research Report
  • [Presentation] アルファ線核医学治療のための小動物イメージングシステムの開発2022

    • Author(s)
      武田伸一郎, 織田忠, 柳下淳, 桂川美穂 他
    • Organizer
      第17回 小動物インビボイメージング研究
    • Related Report
      2022 Annual Research Report
  • [Presentation] Development of a high-sensitivity hard X-ray camera for in vivo imaging of small animals2022

    • Author(s)
      Miho Katsuragawa, Atsushi Yagishita, Shin'ichiro Takeda, Takahiro Minami, Kazunobu Ohnuki, Hirohumi Fujii, Tadayuki Takahashi
    • Organizer
      第16回日本分子イメージング学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 超高分解能の生体内マルチプローブイメージングを実現するCdTe SPECT装置の開発2022

    • Author(s)
      武田伸一郎, 織田忠, 柳下淳, 桂川美穂 他
    • Organizer
      第16回日本分子イメージング学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 酸化的リン酸化阻害剤による脳腫瘍幹細胞低酸素ニッチの制御法2022

    • Author(s)
      サンペトラ オルテア、佐谷秀行
    • Organizer
      第8回がんと代謝研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 脳腫瘍幹細胞の不均一性と治療抵抗性2022

    • Author(s)
      サンペトラ オルテア
    • Organizer
      第42回日本脳神経外科コングレス総会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 宇宙ガンマ線観測用厚型CdTe両面ストリップ検出器の性能評価及び応答の研究2022

    • Author(s)
      南 喬博、桂川美穂, 長澤俊作, 高橋忠幸, 武田伸一郎, 都築豊, 渡辺伸
    • Organizer
      日本物理学会 2022年年次大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 太陽観測ロケット実験FOXSI-4に向けたワイドギャップCdTeストリップ検出器の開発と性能評価II2022

    • Author(s)
      長澤 俊作、南 喬博, 高橋 忠幸, 渡辺 伸, 市橋 正裕, 岩田 季也, 小高 裕和, 高嶋 聡, 谷本 敦, 丹波 翼, 渡邊 泰平, 神谷 好郎, 成影 典之
    • Organizer
      日本天文学会 2022年春季年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 宇宙観測検出器と量子ビームの出会い。新たな応用への架け橋。2022

    • Author(s)
      高橋忠幸
    • Organizer
      日本物理学会 2022年年次大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 二電子性再結合X線の偏光度測定III2022

    • Author(s)
      14.中村信行, 大石晋平, 沼館直樹, 内田悠介, 小高裕和, Xiang Gao, 加藤太治, 高橋忠幸, 都築豊, Xiaomin Tong, 米田浩基, 渡辺伸, 渡邉裕文
    • Organizer
      日本物理学会第77回年次大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Wide-gap CdTe strip detectors for high-resolution imaging in hard X-rays2021

    • Author(s)
      S. Nagasawa, T. Minami, S. Watanabe, T. Takahashi
    • Organizer
      2021 IEEE NSS/MIC/RTSD
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] An application of a Si/CdTe Compton camera for the polarization measurement of hard x-rays from highly charged heavy ions2021

    • Author(s)
      Y. Tsuzuki, S. Watanabe, S. Oishi, N. Nakamura, N. Numadate, H. Odaka, Y. Uchida, H. Yoneda, and T. Takahashi,
    • Organizer
      2021 IEEE NSS/MIC/RTSD
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Production of anti-mouse sphingosine 1-phosphate receptor-4 monoclonal antibody2021

    • Author(s)
      Marika Kurosawa, Akari Kimura, Tamami Kusu, Kenji Chiba, Takashi Masuko, Hideki Yagi
    • Organizer
      日本薬学会第142回年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] CdTe SPECT を用いた担がんマウス微小リンパ節転移巣およびリンパ流路の2核種イメージング法の検証2021

    • Author(s)
      3.柳下 淳, 大貫 和信, 武田 伸一郎, 桂川 美穂, 織田 忠, 梅田 泉, サンペトラ オルテア, 藤井 博史, 高橋 忠幸
    • Organizer
      第23回SNNS研究会学術集会(岐阜)
    • Related Report
      2021 Annual Research Report
  • [Presentation] 太陽観測ロケット実験FOXSI-4に向けたワイドギャップCdTeストリップ検出器の開発と性能評価2021

    • Author(s)
      長澤俊作, 南 喬博, 高橋忠幸, 渡辺伸
    • Organizer
      日本天文学会2021年秋季年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 様々な領域への応用を目指した高効率CdTe 両面ストリップ検出器の性能評価2021

    • Author(s)
      南 喬博, 渡辺 伸, 武田 伸一郎, 桂川 美穂, 高橋 忠幸, 邱 奕寰
    • Organizer
      第82回応用物理学会秋季学術講演会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 負ミュオンによる非破壊イメージングに向けた2mm厚CdTe半導体3次元検出器の開発2021

    • Author(s)
      邱 奕寰,二宮和彦, 武田伸一郎ほか
    • Organizer
      日本放射化学会第65回討論会,
    • Related Report
      2021 Annual Research Report
  • [Presentation] Complex formation of 186Re with various lipophilic ligands for radio-theranostics in comparison with 99mTc2021

    • Author(s)
      Izumi O. Umeda and Hirofumi Fujii
    • Organizer
      第80回日本癌学会学術総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Rhenium-186の錯体形成に関する諸検討2021

    • Author(s)
      梅田 泉、永田みどり、天﨑茜、大貫和信、柳下 淳、桂川美穂、織田忠、武田伸一郎、羽場宏光、藤井博史、高橋忠幸
    • Organizer
      第61回日本核医学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 抗HER1, HER2分子標的薬との併用による、抗HER3抗体の親和性と癌細胞増殖阻害効果の増強2021

    • Author(s)
      沖田 鋼季, 杉浦麗子、山﨑晶貴、加藤和則、遠藤雄一、益子 高
    • Organizer
      第80回日本癌学会学術総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 標的分子の内在化と分解を誘導するモノクローナル抗体の評価:抗がん二重特異性抗体の開発に向けて2021

    • Author(s)
      山﨑晶貴、西田健人、沖田鋼季、石渡俊行、遠藤雄一、富岡佳久、益子 高
    • Organizer
      第80回日本癌学会学術総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 様々な領域への応用をめざした高効率テルル化カドミウム半導体両面ストリップ検出器の開発2021

    • Author(s)
      南喬博, 渡辺 伸, 武田伸一郎, 桂川美穂, 高橋忠幸, 邱奕寰
    • Organizer
      日本物理学会第76回年次大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] CdTe 検出器を用いた負ミュオンによる非破壊三次元イメージング法の開発2021

    • Author(s)
      邱奕寰, 梶野芽都, 篠原厚, 二宮和彦, 武田伸一郎, 桂川美穂, 都丸亮太, 長澤俊作, 藪悟郎, 南喬博, 高橋忠幸, 渡辺伸
    • Organizer
      日本物理学会第76回年次大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 111In-DOTA/90Y-DOTA封入リポソームによるradio-theranosticsの試み2021

    • Author(s)
      梅田 泉、永田みどり、天﨑 茜、大貫和信、柳下 淳、武田伸一郎、桂川美穂、藤井博史、高橋忠幸.
    • Organizer
      日本薬学会第141年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] New development of negative muon experiments using the latest detector technology for space X-ray and γ-ray observations2020

    • Author(s)
      Tadayuki Takahashi
    • Organizer
      J-PARC/MUSE 成果報告会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 宇宙X線ガンマ線検出技術を用いた新たな負ミュオン 実験の展開。原子物理から高精度3D非破壊元素分析まで。2020

    • Author(s)
      高橋 忠幸
    • Organizer
      新学術領域研究「宇宙観測検出器と量子ビームの出会い。新たな応用への架け橋。」 領域研究会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 生体内(in vivo)イメージングのためのCdTe半導体イメージャの開発2020

    • Author(s)
      桂川 美穂
    • Organizer
      新学術領域研究「宇宙観測検出器と量子ビームの出会い。新たな応用への架け橋。」 領域研究会
    • Related Report
      2020 Annual Research Report
  • [Presentation] At-211 分布可視化のための高感度 CdTe 半導体イメージャの開発2020

    • Author(s)
      桂川美穂、武田伸一郎、峰 海里、藪 悟郎、柳下 淳、梅田 泉、高橋忠幸、 渡辺 伸、大貫和信、藤井博史
    • Organizer
      第15回日本分子イメージング学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 111In/90Y封入リポソームを用いたradio-theranostic2020

    • Author(s)
      梅田 泉、角田 瞳、永田みどり、大貫和信、柳下 淳、武田伸一郎、藤井博史、高橋忠幸
    • Organizer
      第60回日本核医学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Interdisciplinary activities for cancer research based on advanced technology of in vivo gamma-ray imaging2019

    • Author(s)
      Tadayuki Takahashi
    • Organizer
      PACIFIC2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of a Low-Noise Front-end ASIC for CdTe Detectors, International Symposium on the Development and Application of Semiconductor Tracking Detectors (HSTD12)2019

    • Author(s)
      T. Kawamura, T. Orita, S. Takeda, Shin Watanabe, Hirokazu Ikeda, Tadayuki Takahashi
    • Organizer
      International Symposium on the Development and Application of Semiconductor Tracking Detectors (HSTD12)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Imaging and spectral performance of a 60 μm pitch CdTe double-sided strip detector2019

    • Author(s)
      S. Nagasawa, K. Furukawa,, L. Glesener, M. Katsuragawa, S. Takeda, S. Watanabe, T. Takahashi
    • Organizer
      nternational Symposium on the Development and Application of Semiconductor Tracking Detectors (HSTD12)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of CdTe Hybrid Pixel ASIC for Hard X-ray Imaging2019

    • Author(s)
      T. Orita, T. Kawamura, K. Mine, S. Takeda, S. Watanabe, H. Ikeda, T. Takahashi
    • Organizer
      International Symposium on the Development and Application of Semiconductor Tracking Detectors (HSTD12)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 超高分解能 CdTe-SPECT 試作機によるマルチプローブ生体イメージングへの展開2019

    • Author(s)
      柳下淳,武田伸一郎,織田忠,桂川美穂,藪悟郎,河村天陽,高橋忠幸,渡辺伸,水間広,金山洋介, 大貫和信,梅田泉,藤井博史
    • Organizer
      日本分子イメージング学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 超高分解能マルチプローブCdTe SPECT装置の開発2019

    • Author(s)
      武田伸一郎、織田忠、柳下淳、桂川美穂、都丸亮太、薮悟郎、高橋忠幸、渡辺伸、水間広、金山洋介、菅原寛孝、森山文基、大貫和信、梅田泉、藤井博史
    • Organizer
      日本分子イメージング学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] CdTe検出器を用いた硬X線イメージング研究2019

    • Author(s)
      武田伸一郎
    • Organizer
      The 2nd Workshop on Quantum Beam Imaging
    • Related Report
      2019 Annual Research Report
  • [Presentation] ラジオセラノスティック製剤を目指した放射性リポソーム2019

    • Author(s)
      梅田 泉,森田智子,浜根友仁子,大貫和信,柳下淳,武田伸一郎,高橋忠幸,藤井博史
    • Organizer
      第59回日本核医学会(松山),
    • Related Report
      2019 Annual Research Report
  • [Presentation] Si/CdTeコンプトンカメラの原子物理実験における偏光測定への応用2019

    • Author(s)
      都築豊, 渡辺伸, 大石晋平, 沼館直樹, 櫻井誠, 渡邉裕文, 中村信行, 内田悠介, 米田浩基, 小高裕和, 高橋 忠幸
    • Organizer
      原子衝突学会第44回年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 8-アミノBODIPYを用いた青色ALDH1蛍光プローブの開発2019

    • Author(s)
      柳下淳,上野匡,梅田泉,土原一哉,浦野泰照
    • Organizer
      日本薬学会第140年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 脳腫瘍幹細胞の低酸素応答と放射線抵抗性の克服2019

    • Author(s)
      サンペトラ オルテア,小池 直義,佐谷 秀行
    • Organizer
      日本放射線腫瘍学会第32回学術大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Toward a new frontier for in-vivo cancer researches, at Kavli IPMU2019

    • Author(s)
      Shin'ichiro Takeda
    • Organizer
      Interdisciplinary approach of applying cutting-edge technologies at the frontier of cancer research
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 高分解能ガンマ線3次元イメージングを目指したCdTe SPECT装置の検出器応答の研究2019

    • Author(s)
      薮 悟朗
    • Organizer
      応用物理学会春季学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Study of 3D image reconstruction using a Si/CdTe semiconductor Compton Camera2018

    • Author(s)
      Goro Yabu
    • Organizer
      the 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Novel and interdisciplinary application of space hard X-ray and gamma-ray detectors2018

    • Author(s)
      Tadayuki Takahashi
    • Organizer
      The 1st Workshop on Quantum Beam Imaging
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Development of a front-end ASIC for CdTe Hybrid Pixel Detector2018

    • Author(s)
      Tadashi Orita
    • Organizer
      International Workshop on Semiconductor Pixel Detectors for Particles and Imaging (PIXEL 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Book] 宇宙物理学ハンドブック2020

    • Author(s)
      高原文郎、家正則、小玉英雄、高橋忠幸
    • Total Pages
      912
    • Publisher
      朝倉書店
    • ISBN
      9784254131277
    • Related Report
      2019 Annual Research Report
  • [Remarks] 宇宙硬エックス線・ガンマ線検出テクノロジーの異分野への展開

    • URL

      https://member.ipmu.jp/SpaceTech_to_QuantumBeam/planned-research/c01/

    • Related Report
      2022 Annual Research Report 2021 Annual Research Report
  • [Remarks] 宇宙観測検出器と量子ビームの出会い。新たな応用への架け橋。

    • URL

      https://member.ipmu.jp/SpaceTech_to_QuantumBeam/planned-research/c01/

    • Related Report
      2020 Annual Research Report 2018 Annual Research Report
  • [Remarks] ガンマ線イメージングの医学応用

    • URL

      https://www.ipmu.jp/en/research-activities/research-program/Gamma-ray_Imaging

    • Related Report
      2020 Annual Research Report
  • [Remarks] C01 宇宙硬エックス線・ガンマ線検出テクノロジーの異分野への展開

    • URL

      https://member.ipmu.jp/SpaceTech_to_QuantumBeam/planned-research/c01/index.html

    • Related Report
      2019 Annual Research Report
  • [Remarks] ガンマ線イメージングの医学応用

    • URL

      https://www.ipmu.jp/ja/research-activities/research-program/Gamma-ray_Imaging

    • Related Report
      2019 Annual Research Report
  • [Patent(Industrial Property Rights)] Aldehyde dehydrogenase detecting blue fluorescent probe2020

    • Inventor(s)
      柳下 淳
    • Industrial Property Rights Holder
      柳下 淳
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Related Report
      2020 Annual Research Report
  • [Patent(Industrial Property Rights)] Time width signal processing method of radiation signal and its application to ASIC2020

    • Inventor(s)
      織田 忠
    • Industrial Property Rights Holder
      織田 忠
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-115866
    • Filing Date
      2020
    • Related Report
      2020 Annual Research Report
  • [Patent(Industrial Property Rights)] アルデヒドロゲナーゼ1A1検出用青色蛍光プローブ2019

    • Inventor(s)
      柳下 淳
    • Industrial Property Rights Holder
      柳下 淳
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-014846
    • Filing Date
      2019
    • Related Report
      2019 Annual Research Report

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Published: 2018-07-20   Modified: 2024-01-30  

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