• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Deciphering Origin and Establishment of Japonesians mainly based on genome sequence data

Planned Research

Project AreaDeciphering Origin and Establishment of Japonesians mainly based on genome sequence data
Project/Area Number 18H05511
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionHokkaido University

Principal Investigator

Osada Naoki  北海道大学, 情報科学研究院, 准教授 (70416270)

Co-Investigator(Kenkyū-buntansha) 五條堀 淳  総合研究大学院大学, 先導科学研究科, 講師 (00506800)
河合 洋介  国立研究開発法人国立国際医療研究センター, その他部局等, 副プロジェクト長 (30435515)
藤本 明洋  東京大学, 大学院医学系研究科(医学部), 教授 (30525853)
Project Period (FY) 2018-06-29 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥49,140,000 (Direct Cost: ¥37,800,000、Indirect Cost: ¥11,340,000)
Fiscal Year 2022: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2021: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2020: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2019: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2018: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
Keywordsゲノム / 日本列島人 / ヤポネシア / 日本列島 / ヒト / 進化 / 遺伝的多様性 / 日本人 / 人口動態 / 集団遺伝学 / ヤポネシア人 / ゲノム配列
Outline of Final Research Achievements

This research project aims to develop methods for accurately estimating the history of the Yaponesians (Japanese archipelago) people using genome sequence data and to elucidate how Yaponesian people reached the Japanese archipelago, admixed, and developed by applying these methods. Focusing on four aspects: haplotypes, rare mutations, sex chromosomes, and non-SNP markers, various analyses are conducted using genome data obtained from other research projects within the project. These analyses include examining the detailed genetic structure of modern humans in the Japanese archipelago, estimating population dynamics from 1,000 years ago, and evaluating the genetic relationship between modern and ancient humans, resulting in many new findings.

Academic Significance and Societal Importance of the Research Achievements

日本列島における人類史を明らかにすることは,東アジアの島嶼地域への初期人類の移住という、世界的に見ても人類学的に非常に興味深い例として知られているだけでなく,われわれ日本人のアイデンティティにもかかわる重要な問題である.さまざまな方面からこのような研究が行われているが,近年急速に発展したゲノム情報を用いた方法は非常に有用であり,今後ますます重要性が増していくだろうと考えられる.本研究計画は、ゲノム配列解析の手法を開発・改良し,それらをプロジェクトで生み出されるデータに適用することで,日本人の祖先が辿った歴史を明らかにし,その知見を社会に還元していくという意義をもっている.

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (137 results)

All 2023 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (2 results) Journal Article (56 results) (of which Int'l Joint Research: 19 results,  Peer Reviewed: 44 results,  Open Access: 38 results) Presentation (71 results) (of which Int'l Joint Research: 17 results,  Invited: 29 results) Book (6 results) Remarks (1 results) Funded Workshop (1 results)

  • [Int'l Joint Research] University College Dublin(アイルランド)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Trinity Collage Dublin(アイルランド)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Localized assembly for long reads enables genome-wide analysis of repetitive regions at single-base resolution in human genomes2023

    • Author(s)
      Ko Ikemoto , Hinano Fujimoto , Akihiro Fujimoto
    • Journal Title

      Hum Genomics

      Volume: 9 Issue: 1 Pages: 21-21

    • DOI

      10.1186/s40246-023-00467-7

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole-genome sequencing analysis of wild house mice (<i>Mus musculus</i>) captured in Madagascar2022

    • Author(s)
      Kazumichi Fujiwara, Marie C. Ranorosoa, Satoshi D. Ohdachi, Satoru Arai, Yuki Sakuma, Hitoshi Suzuki, Naoki Osada
    • Journal Title

      Genes & Genetic Systems

      Volume: 97 Issue: 4 Pages: 193-207

    • DOI

      10.1266/ggs.22-00090

    • ISSN
      1341-7568, 1880-5779
    • Year and Date
      2022-08-01
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Insights into Mus musculus population structure across Eurasia revealed by whole-genome analysis2022

    • Author(s)
      Fujiwara K., Kawai Y., Takada T., Shiroishi T., Saitou N., Suzuki H., and Osada N
    • Journal Title

      Genome Biology and Evolution

      Volume: 14(5) Issue: 5 Pages: 1-14

    • DOI

      10.1093/gbe/evac068

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Comprehensive analysis of microsatellite polymorphisms in human populations2022

    • Author(s)
      Gochi Leo、Kawai Yosuke、Fujimoto Akihiro
    • Journal Title

      Human Genetics

      Volume: 142 Issue: 1 Pages: 45-57

    • DOI

      10.1007/s00439-022-02484-3

    • Related Report
      2022 Annual Research Report
  • [Journal Article] The NBDC-DDBJ imputation server facilitates the use of controlled access reference panel datasets in Japan2022

    • Author(s)
      Hachiya Tsuyoshi、Ishii Manabu、Kawai Yosuke、Khor Seik-Soon、Kawashima Minae、Toyo-Oka Licht、Mitsuhashi Nobutaka、Fukuda Asami、Kodama Yuichi、Fujisawa Takatomo、Tokunaga Katsushi、Takagi Toshihisa
    • Journal Title

      Human Genome Variation

      Volume: 9 Issue: 1 Pages: 48-48

    • DOI

      10.1038/s41439-022-00225-6

    • Related Report
      2022 Annual Research Report
  • [Journal Article] Phylogeographic study using nuclear genome sequences of <i>Asip</i> to infer the origins of ventral fur color variation in the house mouse <i>Mus musculus</i>2021

    • Author(s)
      Takeishi, T., Fujiwara, K., Osada, N., Mita, A., Takada, T., Shiroishi, T., and Suzuki, H.
    • Journal Title

      Genes & Genetic Systems

      Volume: 96 Issue: 6 Pages: 271-284

    • DOI

      10.1266/ggs.21-00075

    • ISSN
      1341-7568, 1880-5779
    • Year and Date
      2021-12-01
    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Demographic history of the brown bear (Ursus artcos) on Hokkaido Island, Japan, based on whole-genomic sequence analysis. Genome Biology and Evolution2021

    • Author(s)
      Endo, Y., Osada, N., Mano, T., and Masuda, R.
    • Journal Title

      Genome Biology and Evolution

      Volume: - Issue: 9

    • DOI

      10.1093/gbe/evab195

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] ヤポネシア人の人口・歴史推定2021

    • Author(s)
      長田直樹
    • Journal Title

      メディカル・サイエンス・ダイジェスト

      Volume: 47 Pages: 476-478

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Exploring models of human migration to the Japanese archipelago using genome-wide genetic data2021

    • Author(s)
      OSADA NAOKI、KAWAI YOSUKE
    • Journal Title

      Anthropological Science

      Volume: 129 Issue: 1 Pages: 45-58

    • DOI

      10.1537/ase.201215

    • NAID

      130008030483

    • ISSN
      0918-7960, 1348-8570
    • Related Report
      2021 Annual Research Report 2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Modern human DNA analyses with special reference to the inner dual-structure model of Yaponesian2021

    • Author(s)
      Jinam T. A., Kawai Y., and Saitou N.
    • Journal Title

      Anthropological Science

      Volume: 129 Issue: 1 Pages: 3-11

    • DOI

      10.1537/ase.201217

    • NAID

      130008030443

    • ISSN
      0918-7960, 1348-8570
    • Related Report
      2021 Annual Research Report 2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Whole genome sequencing with long-reads reveals complex structure and origin of structural variation in human genetic variations and somatic mutations in cancer.2021

    • Author(s)
      Fujimoto A, Wong JH, Yoshii Y, Akiyama S, Tanaka A, Yagi H, Shigemizu D, Nakagawa H, Mizokami M, and Shimada M.
    • Journal Title

      Genome Medicine

      Volume: 13 Issue: 1 Pages: 65-65

    • DOI

      10.1186/s13073-021-00883-1

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Characterization of intermediate-sized insertions using whole-genome sequencing data and analysis of their functional impact on gene expression2021

    • Author(s)
      Ashouri Saeideh、Wong Jing Hao、Nakagawa Hidewaki、Shimada Mihoko、Tokunaga Katsushi、Fujimoto Akihiro
    • Journal Title

      Human Genetics

      Volume: 140 Issue: 8 Pages: 1201-1216

    • DOI

      10.1007/s00439-021-02291-2

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Population dynamics in the Japanese Archipelago since the Pleistocene revealed by the complete mitochondrial genome sequences.2021

    • Author(s)
      Mizuno, F., Gojobori, J., Kumagai, M., Baba, H., Taniguchi, Y., Kondo, O., Matsushita, M., Matsushita, T., Matsuda, F., Higasa, K., Hayashi, M., Wang, L., Kurosaki, K. and Ueda, S.
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-021-91357-2

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] House mouse Mus musculus dispersal in East Eurasia inferred from 98 newly determined complete mitochondrial genome sequences.2021

    • Author(s)
      Li Y, Fujiwara K, Osada N, Kawai Y, Takada T, Kryukov AP, Abe K, Yonekawa H, Shiroishi T, Moriwaki K, Saitou N, Suzuki H
    • Journal Title

      Heredity

      Volume: 126 Issue: 1 Pages: 132-147

    • DOI

      10.1038/s41437-020-00364-y

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Genome-wide SNP data of Izumo and Makurazaki populations support inner-dual structure model for origin of Yamato people2021

    • Author(s)
      Jinam Timothy、Kawai Yosuke、Kamatani Yoichiro、Sonoda Shunro、Makisumi Kanro、Sameshima Hideya、Tokunaga Katsushi、Saitou Naruya
    • Journal Title

      Journal of Human Genetics

      Volume: - Issue: 7 Pages: 681-687

    • DOI

      10.1038/s10038-020-00898-3

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Testing sex-biased admixture origin of macaque species using autosomal and X-chromosomal genomic sequences2020

    • Author(s)
      Osada Naoki、Matsudaira Kazunari、Hamada Yuzuru、Malaivijitnond Suchinda
    • Journal Title

      Genome Biology and Evolution

      Volume: 13 Pages: 1-14

    • DOI

      10.1093/gbe/evaa209

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identification of Characteristic Genomic Markers in Human Hepatoma HuH-7 and Huh7.5.1-8 Cell Lines2020

    • Author(s)
      Kawamoto M#, Yamaji T#, Saito K, Shirasago Y, Satomura K, Endo T, Fukasawa M, Hanada K, Osada N.
    • Journal Title

      Front Genet

      Volume: 11 Pages: 546106-546106

    • DOI

      10.3389/fgene.2020.546106

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparative characterization of flavivirus production in two cell lines: Human hepatoma-derived Huh7.5.1-8 and African green monkey kidney-derived Vero2020

    • Author(s)
      Kyoko Saito, Masayoshi Fukasawa, Yoshitaka Shirasago, Ryosuke Suzuki, Naoki Osada, Toshiyuki Yamaji, Takaji Wakita, Eiji Konishi, Kentaro Hanada
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 4 Pages: e0232274-e0232274

    • DOI

      10.1371/journal.pone.0232274

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels.2020

    • Author(s)
      Higashino T, Morimoto K, Nakaoka H, Toyoda Y, Kawamura Y, Shimizu S, Nakamura T, Hosomichi K, Nakayama A, Ooyama K, Ooyama H, Shimizu T, Ueno M, Ito T, Tamura T, Naito M, Nakashima H, Kawaguchi M, Takao M, Kawai Y, Osada N, Ichida K, Yamamoto K, Suzuki H, Shinomiya N, Inoue I, Takada T, Matsuo H.
    • Journal Title

      Ann Rheum Dis.

      Volume: 79(1) Issue: 1 Pages: 164-166

    • DOI

      10.1136/annrheumdis-2019-216044

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multiregional whole‐genome sequencing of hepatocellular carcinoma with nodule‐in‐nodule appearance reveals stepwise cancer evolution2020

    • Author(s)
      Takeda Haruhiko、Takai Atsushi、Kumagai Ken、Iguchi Eriko、Arasawa Soichi、Eso Yuji、Shimizu Takahiro、Ueda Yoshihide、Taura Kojiro、Uemoto Shinji、Kita Ryuichi、Haga Hironori、Marusawa Hiroyuki、Fujimoto Akihiro、Seno Hiroshi
    • Journal Title

      The Journal of Pathology

      Volume: 252 Issue: 4 Pages: 398-410

    • DOI

      10.1002/path.5533

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H2020

    • Author(s)
      Shibayama,Y., Takahashi, K., Yamaguchi, H., Yasuda, J., Yamazaki, D., Rahman, A., Fujimori, T., Fujisawa, Y., Takai, S., Furukawa, T., Nakagawa, T., Ohsaki, H., Kobara, H., Wong, J.H., Masaki, T., Yuzawa, Y., Kiyomoto, H., Yachida, S., Fujimoto, A., Nishiyama, A.
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 724-724

    • DOI

      10.1038/s42003-020-01434-x

    • NAID

      130008001357

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Whole genome sequencing analysis identifies recurrent structural alterations in esophageal squamous cell carcinoma2020

    • Author(s)
      Dutta Munmee、Nakagawa Hidewaki、Kato Hiroaki、Maejima Kazuhiro、Sasagawa Shota、Nakano Kaoru、Sasaki-Oku Aya、Fujimoto Akihiro、Mateos Ra?l Nicol?s、Patil Ashwini、Tanaka Hiroko、Miyano Satoru、Yasuda Takushi、Nakai Kenta、Fujita Masashi
    • Journal Title

      PeerJ

      Volume: 8 Pages: e9294-e9294

    • DOI

      10.7717/peerj.9294

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evolutionary History of the Risk of SNPs for Diffuse-Type Gastric Cancer in the Japanese Population2020

    • Author(s)
      Iwasaki Risa L.、Ishiya Koji、Kanzawa-Kiriyama Hideaki、Kawai Yosuke、Gojobori Jun、Satta Yoko
    • Journal Title

      Genes

      Volume: 11 Issue: 7 Pages: 775-775

    • DOI

      10.3390/genes11070775

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Do Genes Associated with Dyslexia of Chinese Characters Evolve Neutrally?2020

    • Author(s)
      Nishiyama Kumiko V.、Satta Yoko、Gojobori Jun
    • Journal Title

      Genes

      Volume: 11 Issue: 6 Pages: 658-658

    • DOI

      10.3390/genes11060658

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations.2020

    • Author(s)
      Fujita M, Yamaguchi R, Hasegawa T, Shimada S, Arihiro K, Hayashi S, Maejima K, Nakano K, Fujimoto A, Ono A, Aikata H, Ueno M, Hayami S, Tanaka H, Miyano S, Yamaue H, Chayama K, Kakimi K, Tanaka S, Imoto S, Nakagawa H.
    • Journal Title

      EBioMedicine

      Volume: 53 Pages: 102659-102659

    • DOI

      10.1016/j.ebiom.2020.102659

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Rare allele sharing in the East Asian2020

    • Author(s)
      Gojobori, J
    • Journal Title

      Archivio per l’Antropologia e la Etnologia

      Volume: CL

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types2020

    • Author(s)
      Fujimoto A*, Fujita M, Hasegawa T, Wong JH, Maejima K, Oku-Sasaki A, Nakano K, Shiraishi Y, Miyano S, Yamamoto G, Akagi K, Imoto S, and Nakagawa H
    • Journal Title

      Genome Research

      Volume: 30 Issue: 3 Pages: 334-34

    • DOI

      10.1101/gr.255026.119

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Pan-cancer analysis of whole genomes2020

    • Author(s)
      The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
    • Journal Title

      Nature

      Volume: 578 Issue: 7793 Pages: 82-93

    • DOI

      10.1038/s41586-020-1969-6

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Implications of HLA diversity among regions for bone marrow donor searches in Japan2020

    • Author(s)
      Hashimoto S, Nakajima F, Imanishi T, Kawai Y, Kato K, Kimura T, Miyata S, Takanashi M, Nishio M, Tokunaga K, Satake M
    • Journal Title

      HLA

      Volume: in press Issue: 1 Pages: 24-42

    • DOI

      10.1111/tan.13881

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 港川人のミトコンドリア DNA全塩基配列からわかること2020

    • Author(s)
      水野文月,五條堀淳
    • Journal Title

      学術の動向

      Volume: 25 Pages: 2-2

    • NAID

      130007865037

    • Related Report
      2019 Annual Research Report
  • [Journal Article] eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA2019

    • Author(s)
      Mizuno Kei、Akamatsu Shusuke、Sumiyoshi Takayuki、Wong Jing Hao、Fujita Masashi et al.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 15017-15017

    • DOI

      10.1038/s41598-019-51459-4

    • NAID

      120006734882

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan2019

    • Author(s)
      Kanzawa-Kiriyama Hideaki、Jinam Timothy A.、Kawai Yosuke、Sato Takehiro、Hosomichi Kazuyoshi、Tajima Atsushi、Adachi Noboru、Matsumura Hirofumi、Kryukov Kirill、Saitou Naruya、Shinoda Ken-Ichi
    • Journal Title

      Anthropological Science

      Volume: 127 Issue: 2 Pages: 83-108

    • DOI

      10.1537/ase.190415

    • NAID

      130007696474

    • ISSN
      0918-7960, 1348-8570
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A key metabolic gene for recurrent freshwater colonization and radiation in fishes2019

    • Author(s)
      Ishikawa Asano, Kabeya Naoki, Ikeya Koki, Kakioka Ryo, Cech Jennifer N., Osada Naoki, Leal Miguel C., Inoue Jun, Kume Manabu, Toyoda Atsushi, Tezuka Ayumi, Nagano Atsushi J., Yamasaki Yo Y., Suzuki Yuto, Kokita Tomoyuki, Takahashi Hiroshi et al.
    • Journal Title

      Science

      Volume: 364 Issue: 6443 Pages: 886-889

    • DOI

      10.1126/science.aau5656

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Genetic diversity and population structure of Glossina morsitans morsitans in the active foci of human African trypanosomiasis in Zambia and Malawi2019

    • Author(s)
      Yukiko Nakamura, Junya Yamagishi, Kyoko Hayashida, Naoki Osada, Elisha Chatanga, Cornelius Mweempwa, Kalinga Chilongo, John Chisi, Jenelisa Musaya, Ryosuke Omori, Noboru Inoue, Boniface Namangala, Chihiro Sugimoto
    • Journal Title

      PLoS Negl. Trop. Dis

      Volume: 13 Issue: 7 Pages: e0007568-e0007568

    • DOI

      10.1371/journal.pntd.0007568

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Achiasmy and sex chromosome evolution2019

    • Author(s)
      Kazuhiro Satomura, Naoki Osada, Toshinori Endo
    • Journal Title

      Ecological Genetics and Genomics

      Volume: 13 Pages: 1000046-1000046

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 日本人ゲノム解析において集団差をどう考えるか2019

    • Author(s)
      河合洋介
    • Journal Title

      IBD Research

      Volume: 13 Pages: 31-34

    • Related Report
      2019 Annual Research Report
  • [Journal Article] 東アジアの人々のゲノム多様性2019

    • Author(s)
      徳永勝士,河合洋介
    • Journal Title

      腎臓内科・泌尿器科

      Volume: 10 Pages: 561-565

    • NAID

      40022102238

    • Related Report
      2019 Annual Research Report
  • [Journal Article] ヤポネシア人の歴史の解明が医学にもたらすもの2019

    • Author(s)
      長田直樹
    • Journal Title

      実験医学

      Volume: 37 Pages: 926-929

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Clinical utility of androgen receptor gene aberrations in circulating cell-free DNA as a biomarker for treatment of castration-resistant prostate cancer2019

    • Author(s)
      Sumiyoshi Takayuki、Mizuno Kei、Yamasaki Toshinari、Miyazaki Yu、Makino Yuki、Okasho Kosuke、Li Xin、Utsunomiya Noriaki、Goto Takayuki、Kobayashi Takashi、Terada Naoki、Inoue Takahiro、Kamba Tomomi、Fujimoto Akihiro、Ogawa Osamu、Akamatsu Shusuke
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 4030-4030

    • DOI

      10.1038/s41598-019-40719-y

    • NAID

      120006709427

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan2019

    • Author(s)
      Kanzawa-Kiriyama H, Jinam TA, Kawai Y, Sato T, Hosomichi K, Tajima A, Adachi N, Matsumura H, Kryukov K, Saitou N and Shinoda K
    • Journal Title

      Anthropological Science

      Volume: -

    • NAID

      130007696474

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.332019

    • Author(s)
      Hitomi, Y. Ueno, K. Kawai, Y. Nishida, N. , Umemura, T. et al
    • Journal Title

      Sci Rep

      Volume: 9 Issue: 1 Pages: 102-102

    • DOI

      10.1038/s41598-018-36490-1

    • NAID

      120006715480

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Novel endogenous simian retroviral integrations in Vero cells: implications for quality control of a human vaccine cell substrate2018

    • Author(s)
      Sakuma Chisato、Sekizuka Tsuyoshi、Kuroda Makoto、Kasai Fumio、Saito Kyoko、Ikeda Masaki、Yamaji Toshiyuki、Osada Naoki、Hanada Kentaro
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 644-644

    • DOI

      10.1038/s41598-017-18934-2

    • NAID

      120006401475

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comprehensive phylogenomic analysis reveals a novel cluster of simian endogenous retroviral sequences in Colobinae monkeys2018

    • Author(s)
      Ikeda Masaki、Satomura Kazuhiro、Sekizuka Tsuyoshi、Hanada Kentaro、Endo Toshinori、Osada Naoki
    • Journal Title

      American Journal of Primatology

      Volume: 80 Issue: 7

    • DOI

      10.1002/ajp.22882

    • NAID

      120006643589

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole Genome Sequencing of a Vietnamese Family from a Dioxin Contamination Hotspot Reveals Novel Variants in the Son with Undiagnosed Intellectual Disability2018

    • Author(s)
      Nguyen Dang、Nguyen Hai、Nguyen Thuy、Nguyen Thi、Nakano Kaoru、Maejima Kazuhiro、Sasaki-Oku Aya、Nguyen Van、Nguyen Duy、Le Bach、Wong Jing、Tsunoda Tatsuhiko、Nakagawa Hidewaki、Fujimoto Akihiro、Nong Van
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 15 Issue: 12 Pages: 2629-2629

    • DOI

      10.3390/ijerph15122629

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis2018

    • Author(s)
      Shigemizu Daichi、Miya Fuyuki、Akiyama Shintaro、Okuda Shujiro、Boroevich Keith A、Fujimoto Akihiro、Nakagawa Hidewaki、Ozaki Kouichi、Niida Shumpei、Kanemura Yonehiro、Okamoto Nobuhiko、Saitoh Shinji、Kato Mitsuhiro、Yamasaki Mami、Matsunaga Tatsuo、Mutai Hideki、Kosaki Kenjiro、Tsunoda Tatsuhiko
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 5608-5608

    • DOI

      10.1038/s41598-018-23978-z

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Loss-of-function mutations in Zn-finger DNA-binding domain of <i>HNF4A</i> cause aberrant transcriptional regulation in liver cancer2018

    • Author(s)
      Taniguchi Hiroaki、Fujimoto Akihiro、Kono Hidetoshi、Furuta Mayuko、Fujita Masashi、Nakagawa Hidewaki
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 40 Pages: 26144-26156

    • DOI

      10.18632/oncotarget.25456

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants.2018

    • Author(s)
      Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
    • Journal Title

      Cell Mol Gastroenterol Hepatol

      Volume: 7 Issue: 3 Pages: 515-532

    • DOI

      10.1016/j.jcmgh.2018.11.006

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn’s Disease in Japanese Individuals2018

    • Author(s)
      Kakuta Yoichi、Kawai Yosuke、Naito Takeo、Hirano Atsushi、Umeno Junji、Fuyuno Yuta、Liu Zhenqiu、Li Dalin、Nakano Takeru、Izumiyama Yasuhiro、Ichikawa Ryo、Okamoto Daisuke、et al.
    • Journal Title

      Journal of Crohn's and Colitis

      Volume: - Issue: 5 Pages: 2019-2019

    • DOI

      10.1093/ecco-jcc/jjy197

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy2018

    • Author(s)
      Latt Khun Zaw、Honda Kenjiro、Thiri Myo、Hitomi Yuki、Omae Yosuke、Sawai Hiromi、Kawai Yosuke、Teraguchi Shunsuke、Ueno Kazuko、Nagasaki Masao、Mabuchi Akihiko、Kaga Hajime、Komatsuda Atsushi、Tokunaga Katsushi、Noiri Eisei
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 15576-15576

    • DOI

      10.1038/s41598-018-33612-7

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project2018

    • Author(s)
      Yasuda Jun、et al.,
    • Journal Title

      BMC Genomics

      Volume: 19 Issue: 1 Pages: 551-551

    • DOI

      10.1186/s12864-018-4942-0

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals article2018

    • Author(s)
      Y Yamaguchi-Kabata, J Yasuda, O Tanabe, Y Suzuki, H Kawame, N Fuse, M Nagasaki, Y Kawai, K Kojima, F Katsuoka, S Saito, I Danjoh, I Motoike, R Yamashita, S Koshiba, D Saigusa, G Tamiya, S Kure, N Yaegashi, Y Kawaguchi, F Nagami, S Kuriyama, J Sugawara, N Minegishi, A Hozawa, T Takai-Igarashi, K Kinoshita, M Yamamoto.
    • Journal Title

      Journal of Human Genetics.

      Volume: 63 Issue: 2 Pages: 213

    • DOI

      10.1038/s10038-017-0347-1

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Involvement of chalcone reductase in the soybean isoflavone metabolon: identification of GmCHR5, which interacts with 2-hydroxyisoflavanone synthase2018

    • Author(s)
      Mameda Ryo、Waki Toshiyuki、Kawai Yosuke、Takahashi Seiji、Nakayama Toru
    • Journal Title

      The Plant Journal

      Volume: 96 Issue: 1 Pages: 56-74

    • DOI

      10.1111/tpj.14014

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Strong Association of the HLA-DR/DQ Locus with Childhood Steroid-Sensitive Nephrotic Syndrome in the Japanese Population.2018

    • Author(s)
      Jia X, Horinouchi T, Hitomi Y, Shono A, Khor SS, Omae Y, Kojima K, Kawai Y, Nagasaki M, Kaku Y, Okamoto T, Ohwada Y, Ohta K, Okuda Y, Fujimaru R, Hatae K, Kumagai N, Sawanobori E, Nakazato H, Ohtsuka Y, Nakanishi K, Shima Y, Tanaka R, Ashida A, Kamei K, Ishikura K, Nozu K, Tokunaga K, Iijima K
    • Journal Title

      J Am Soc Nephrol.

      Volume: 29 Issue: 8 Pages: 2189-2199

    • DOI

      10.1681/asn.2017080859

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 進化遺伝学とがんゲノム解析2018

    • Author(s)
      藤本明洋
    • Journal Title

      実験医学

      Volume: 増刊号 Pages: 105-109

    • Related Report
      2018 Annual Research Report
  • [Journal Article] ゲノムシークエンスデータの情報解析2018

    • Author(s)
      藤本明洋
    • Journal Title

      生物物理

      Volume: 58 Pages: 001-003

    • NAID

      130007378613

    • Related Report
      2018 Annual Research Report
  • [Journal Article] 肝癌の全ゲノムシークエンス解析2018

    • Author(s)
      藤本明洋
    • Journal Title

      医学のあゆみ

      Volume: 8月4日号 Pages: 399-404

    • Related Report
      2018 Annual Research Report
  • [Presentation] Hybrids meet in Japan: pattern and mode of genomic admixture between subspecies of wild house mice (Mus musculus) in East Asia2023

    • Author(s)
      Kazumichi Fujiwara, Shunpei Kubo, Tomoki Yano, Toshinori Endo, Toyoyuki Takada, Toshihiko Shiroishi, Hitoshi Suzuki, Naoki Osada
    • Organizer
      IMGC2023
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ゲノムから探る人類と野生ハツカネズミの歴史2022

    • Author(s)
      長田直樹
    • Organizer
      日本遺伝学会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] The genetic diversity of Japanese populations inferred from the whole genome sequencing data2022

    • Author(s)
      Kawai Y., Watababe Y., Omae Y., Miyahara R., Khor SS., Noiri E. & Tokunaga, K
    • Organizer
      American Society of Human Genetics
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 全ゲノムシークエンスデータから探る日本列島人の遺伝的多様性の起源2022

    • Author(s)
      河合洋介, 大前陽輔, 野入英世, 徳永勝士
    • Organizer
      日本人類遺伝学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 現代日本列島人の地域的遺伝多様性2022

    • Author(s)
      河合洋介
    • Organizer
      日本進化学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Comprehensive analysis of microsatellite polymorphisms in human populations2022

    • Author(s)
      郷地麗央、河合洋介、藤本明洋
    • Organizer
      日本人類遺伝学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 長鎖シークエンス技術を用いたゲノム、トランスクリプトーム解析2022

    • Author(s)
      藤本明洋
    • Organizer
      日本人類遺伝学会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Whole genome and transcriptome sequencing of human cancer using long-read sequencing technology2022

    • Author(s)
      藤本明洋
    • Organizer
      4th International Conference on Vocational Innovation and Applied Science
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 長鎖シークエンス技術を用いたヒトゲノム解析2022

    • Author(s)
      藤本明洋
    • Organizer
      日本進化学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] マダガスカル産野生ハツカネズミの全ゲノム配列を用いた遺伝的背景の解明2022

    • Author(s)
      藤原一道,Marie C. Ranorosoa,大舘智志,新井智,佐久間有希,鈴木仁,長田直樹
    • Organizer
      日本遺伝学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 日本産野生ハツカネズミにおける適応進化にかかわるゲノム領域の探索2022

    • Author(s)
      久保俊平,藤原一道,遠藤俊徳,鈴木仁,長田直樹
    • Organizer
      日本遺伝学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 縮約ゲノム解析による日本産モグラ類(Mogera imaizumii, Mogera wogura)の系統地理学的解析2022

    • Author(s)
      角井建,木下豪太,原田正史,佐藤淳,郷康広,辰本将司,三橋れい子,鈴木仁,長田直樹
    • Organizer
      日本遺伝学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 集団ゲノム配列解析による東アジアにおける野生ハツカネズミの移住・混合様式の解明2022

    • Author(s)
      藤原一道,鈴木仁,長田直樹
    • Organizer
      日本進化学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] ヒグマはどのように分散し,定着したかー全ゲノム解析によるユーラシア内陸部と島嶼のヒグマの移動史ー2022

    • Author(s)
      遠藤優,長田直樹,間野勉,Alexei V. Abramov,増田隆一
    • Organizer
      日本進化学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 日本産野生ハツカネズミにおいて適応的遺伝子侵入を受けたゲノム領域の探索2022

    • Author(s)
      久保俊平,藤原一道,遠藤俊徳,鈴木仁,長田直樹
    • Organizer
      日本分子生物学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] ニホンザルの分岐年代推定および過去の集団サイズ減少がゲノムに与えた影響の考察2022

    • Author(s)
      大倉拓真,遠藤俊徳,長田直樹
    • Organizer
      日本分子生物学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 野生ハツカネズミの全ゲノム集団解析:亜種間比較と移住・混合様式の解明2022

    • Author(s)
      藤原一道,鈴木仁,長田直樹
    • Organizer
      日本分子生物学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 古代・現代人ゲノムデータをもとにしたヤポネシアへの人類移住経路の考察2021

    • Author(s)
      長田直樹
    • Organizer
      第75回日本人類学会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 現代・古代人ゲノム情報を用いた日本列島への移住経路と混合様式の推定2021

    • Author(s)
      長田直樹
    • Organizer
      日本人類遺伝学会第67回大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 現代ヤマト人のゲノムから探るヤポネシア人成立の歴史2021

    • Author(s)
      河合洋介
    • Organizer
      日本人類遺伝学会第66回大会/第28回日本遺伝子診療学会大会シンポジウム
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] ナショナルセンターバイオバンクネットワークにおける全ゲノムシークエンス解析の取り組み2021

    • Author(s)
      河合洋介
    • Organizer
      日本人類遺伝学会第66回大会/第28回日本遺伝子診療学会大会シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] ロングリードをもちいたゲノム構造解析2021

    • Author(s)
      藤本明洋
    • Organizer
      日本人類遺伝学会第66回大会/第28回日本遺伝子診療学会大会シンポジウム
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Comprehensive analysis of microsatellites polymorphism in the human population2021

    • Author(s)
      郷地麗央、河合洋介、嶋多美穂子、藤本明洋
    • Organizer
      日本人類遺伝学会第66回大会/第28回日本遺伝子診療学会大会シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] Development of a haplotype-resolved local assembly tool with nanopore data2021

    • Author(s)
      池本滉、藤本明洋
    • Organizer
      日本人類遺伝学会第66回大会/第28回日本遺伝子診療学会大会シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] The investigation of the sign of selection on genes associated with dyslexia of Chinese characters.2021

    • Author(s)
      Nishiyama, K., Satta, Y. & Gojobori, J.
    • Organizer
      Cultural Evolution Society Conference
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 漢字の識字障害関連遺伝子群に対する自然選択の検定2021

    • Author(s)
      西山久美子, 颯田葉子, 五條堀淳
    • Organizer
      第75回 日本人類学会大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] ヒト東アジア集団において識字障害関連遺伝子DCDC2上に見られる自然選択の痕跡について2021

    • Author(s)
      西山久美子, 颯田葉子, 五條堀淳
    • Organizer
      日本進化学会第23回東京大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] PCA-UMAPを用いた現代および古代東アジア人の集団構造解析2021

    • Author(s)
      久保俊平, 遠藤俊徳, 長田直樹
    • Organizer
      第23回日本進化学会大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 全ゲノム配列データを用いたユーラシア産ハツカネズミMus musculusの系統解析2021

    • Author(s)
      藤原一道, 河合洋介, 森脇和郎, 高田豊行, 城石俊彦, 斎藤成也, 鈴木仁, 長田直樹
    • Organizer
      第23回日本進化学会大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Whole genome sequencing with long-reads reveals complex structure and origin of structural variation in human genetic variations and somatic mutations in cancer2021

    • Author(s)
      藤本明洋
    • Organizer
      Genome Concept Centennial Conference
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Genome-wide genetic diversity of wild house mice across Eurasia2021

    • Author(s)
      長田直樹
    • Organizer
      Genome Concept Centennial Conference
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] マカク属7種のゲノム解析による進化モデルの構築2020

    • Author(s)
      長田直樹,松平一成,濱田穣,Malaivijitnond Suchinda
    • Organizer
      第36回日本霊長類学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ゲノム配列データからヤポネシア人の起源について考える2020

    • Author(s)
      長田直樹
    • Organizer
      第22回日本進化学会オンライン大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 長鎖シークエンス技術を用いた構造多型/変異の検出とそれらの起源の推定2020

    • Author(s)
      藤本明洋
    • Organizer
      日本人類学会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Whole genome sequencing with long-reads reveals complex structure and origin of structural variation in human genetic variations and somatic mutations in cancer2020

    • Author(s)
      藤本明洋
    • Organizer
      日本人類遺伝学会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Rare allele sharing in Yaponesians and its surrounding populations2020

    • Author(s)
      五條堀淳
    • Organizer
      第22回日本進化学会オンライン大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Demographic inference of human population from haplotype sharing information. The 2019 SMBE conference2019

    • Author(s)
      Yosuke Kawai
    • Organizer
      SMBE 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Analysis of Mutations and Protein Stability on Human Mitochondrial DNA Haplogroups2019

    • Author(s)
      Kazumichi Fujiwara, Toshinori Endo, Naoki Osada
    • Organizer
      SMBE 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ハプロタイプ共有長の分布から推定する東アジア人の集団史2019

    • Author(s)
      河合洋介
    • Organizer
      日本進化学会第21回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Identification of structural variations and analysis of their functional roles2019

    • Author(s)
      藤本明洋
    • Organizer
      日本進化学会第21回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Genetic diversity of wild house mice (Mus musculus) using whole-genome sequences of multiple samples2019

    • Author(s)
      藤原一道,長田直樹,鈴木仁
    • Organizer
      日本進化学会第21回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] The negative selection pressure on autosomal recessive congenital ichthoyosis is weaker in African population2019

    • Author(s)
      東野俊英,長田直樹
    • Organizer
      日本進化学会第21回大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Temporal change of protein stability in human mitochondria during out-of-Africa migration2019

    • Author(s)
      藤原一道,里村和浩,遠藤俊徳,長田直樹
    • Organizer
      日本進化学会第21回大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Identification of structural variations and analysis of their functional roles2019

    • Author(s)
      藤本明洋
    • Organizer
      日本癌学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 長鎖シークエンス技術を用いた癌の全ゲノムシークエンス2019

    • Author(s)
      藤本明洋
    • Organizer
      日本人類遺伝学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Population Genetics2019

    • Author(s)
      Akihiro Fujimoto
    • Organizer
      InCoB
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Identification of structural variations and analysis of their functional roles2019

    • Author(s)
      Akihiro Fujimoto
    • Organizer
      InCoB
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ミトコンドリア塩基配列から推定された日本人集団特異的な有効集団サイズの増加2019

    • Author(s)
      五條堀 淳,日笠 幸一郎,松田 文彦,石谷 孔司,水野 文月,熊谷 真彦,植田 信太郎
    • Organizer
      第73回日本人類学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] ハツカネズミ(Mus musculus)亜種を用いた全ゲノム集団解析ハツカネズミ(Mus musculus)亜種を用いた全ゲノム集団解析2019

    • Author(s)
      藤原一道,河合洋介,斎藤成也,長田直樹,鈴木仁
    • Organizer
      第91回日本遺伝学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 構造異常/構造多型の検出と機能的意義の解析2019

    • Author(s)
      藤本明洋
    • Organizer
      ナノポア現場の会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 情報解析と人類遺伝学2019

    • Author(s)
      藤本明洋
    • Organizer
      遺伝統計学・夏の学校
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] がんゲノム配列決定と今後の課題 -B型・C型肝炎に由来する肝癌の全ゲノム配列解析を例に-2019

    • Author(s)
      藤本明洋
    • Organizer
      京大小児科血液腫瘍研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 「港川人骨のミトコンドリア DNA 全塩基配列からわかること」2019

    • Author(s)
      五條堀淳,水野文月
    • Organizer
      日本学術会議シンポジウム「日本旧石器人研究の発展:沖縄の現場から」
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] ヒトゲノムの多様性をどのように解析するのか2019

    • Author(s)
      長田直樹
    • Organizer
      BI人材育成講座
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] ソフトウェア講習2019

    • Author(s)
      長田直樹
    • Organizer
      第3回木村資生記念進化学セミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Big data in biology: perspectives of genomic diversity studies2019

    • Author(s)
      Naoki Osada
    • Organizer
      Winter International Symposium on Big-Data, Cybersecurity and IoT
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 性による移住率の偏りをゲノムデータから推定する2018

    • Author(s)
      長田直樹
    • Organizer
      第72回日本人類学会大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ミトコンドリアDNAハプログループに注目した,ヒトミトコンドリアタンパク質複合体IVにおける突然変異とタンパク質構造安定性に関する研究2018

    • Author(s)
      藤原一道,遠藤俊徳,長田直樹
    • Organizer
      第72回日本人類学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ミトコンドリアタンパク質複合体IVでの突然変異とそのタンパク質の構造安定性が与える影響について2018

    • Author(s)
      藤原一道,遠藤俊徳,長田直樹
    • Organizer
      第90回日本遺伝学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 霊長類ミトコンドリア遺伝子における多重置換に対する自然選択2018

    • Author(s)
      里村和浩,長田直樹,遠藤俊徳
    • Organizer
      第90回日本遺伝学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Understanding the relationship among the structural and functional properties of amino acid changes to predict the effect of mutations on human beta globin gene2018

    • Author(s)
      Sangeetha Udani Ratnayake, Toshinori Endo, Naoki Osada
    • Organizer
      第90回日本遺伝学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Predicting disease causality of mutations in human beta globin gene2018

    • Author(s)
      Sangeetha Udani Ratnayake, Toshinori Endo, Naoki Osada
    • Organizer
      SMBE2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Hybrid type of nuclear and plastid DNAs suggests the hypothesis for ancient propagation of American bottle gourd (Lagenaria siceraria)2018

    • Author(s)
      Dai Watabe, Hiroshi Yuasa, Naoki Osada, Kazuhiro Satomura, Toshinori endo
    • Organizer
      SMBE2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Search for the factors related to HCV replication in the HuH-7 cell line lineages2018

    • Author(s)
      Masaki Kawamoto, Toshinori Endo, Masayoshi Fukasawa, Kentaro Hanada, Naoki Osada
    • Organizer
      SMBE2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Compensatory back mutations in mitochondrial genome of primates2018

    • Author(s)
      Kazuhiro Satomura, Naoki Osada, Toshinori Endo
    • Organizer
      SMBE2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 全ゲノム塩基配列を用いたヤポネシアとその周辺集団の解析2018

    • Author(s)
      五條堀淳
    • Organizer
      第72回日本人類学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Genome-wide genetic variation of people in Japan and its implication of demographic history2018

    • Author(s)
      Kawai Y, Mimori T, Hitomi Y, Khor SS, Gervais O, Nagasaki M and Tokunaga K
    • Organizer
      SMBE2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types2018

    • Author(s)
      藤本明洋
    • Organizer
      アメリカ人類遺伝学会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Identification of structural variations and analysis of their functional roles2018

    • Author(s)
      藤本明洋
    • Organizer
      日本分子生物学会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ヒトのゲノム配列の解析と今後の課題;ゲノム解析の基礎、がんゲノム.研究、リキッドバイオプシーの個別化医療への応用2018

    • Author(s)
      藤本明洋
    • Organizer
      薬物動態談話会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ヒト肝癌のゲノム異常の包括的解析と今後の課題2018

    • Author(s)
      藤本明洋
    • Organizer
      関西肝癌局所療法研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Book] 遺伝学の百科事典2022

    • Author(s)
      日本遺伝学会(編)
    • Total Pages
      690
    • Publisher
      丸善出版
    • ISBN
      9784621306604
    • Related Report
      2021 Annual Research Report
  • [Book] ヒトの分子遺伝学2021

    • Author(s)
      戸田 達史、井上 聡、松本 直通(編)
    • Total Pages
      904
    • Publisher
      メディカル・サイエンス・インターナショナル
    • ISBN
      9784815730321
    • Related Report
      2021 Annual Research Report
  • [Book] ヒトゲノム事典2021

    • Author(s)
      井ノ上 逸朗, 今西 規, 河村 正二, 斎藤 成也, 颯田 葉子, 田嶋 敦(編)
    • Total Pages
      448
    • Publisher
      一色出版
    • ISBN
      9784910389127
    • Related Report
      2021 Annual Research Report
  • [Book] Evolution of the Human Genome II: Human Evolution Viewed from Genomes (Evolutionary Studies)2021

    • Author(s)
      Naruya Saitou (ed)
    • Total Pages
      268
    • Publisher
      Springer
    • ISBN
      9784431569022
    • Related Report
      2021 Annual Research Report
  • [Book] 最新DNA研究が解き明かす。日本人の誕生2020

    • Author(s)
      斎藤成也、木村亮介、鈴木留美子、河合洋介、松波雅俊
    • Total Pages
      240
    • Publisher
      秀和システム
    • ISBN
      9784798060224
    • Related Report
      2020 Annual Research Report
  • [Book] 進化で読み解く バイオインフォマティクス入門2019

    • Author(s)
      長田 直樹
    • Total Pages
      232
    • Publisher
      森北出版
    • ISBN
      9784627261419
    • Related Report
      2019 Annual Research Report
  • [Remarks] ヤポネシアゲノム

    • URL

      http://www.yaponesian.jp/

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] New development of human genome diversity studies2019

    • Related Report
      2019 Annual Research Report

URL: 

Published: 2018-07-20   Modified: 2024-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi