| Budget Amount *help |
¥132,210,000 (Direct Cost: ¥101,700,000、Indirect Cost: ¥30,510,000)
Fiscal Year 2022: ¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Fiscal Year 2021: ¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Fiscal Year 2020: ¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Fiscal Year 2019: ¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Fiscal Year 2018: ¥28,730,000 (Direct Cost: ¥22,100,000、Indirect Cost: ¥6,630,000)
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| Outline of Final Research Achievements |
Chromatin and nuclear structures undergo drastic changes during the transition from mitosis to meiosis. Global organization of the nucleus and local structures of chromatin are major factors that determine chromatin potential. In this study, using fission yeast as a model organism, we have analyzed the nuclear organization and chromatin structures during mitosis and meiosis. Specifically, we focused on (1) interaction with nuclear membranes, (2) interaction with noncoding RNA, and (3) histone modification. We elucidated the mechanism of alteration of nuclear and chromatin structures during the transition from mitosis to meiosis.
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