Elementary process of molecular recognition from cluster to cell
Project Area | Molecular Science for Supra Functional Systems ? Development of Advanced Methods for Exploring Elementary Process |
Project/Area Number |
19056002
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Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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Allocation Type | Single-year Grants |
Review Section |
Science and Engineering
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Research Institution | Tokyo Institute of Technology |
Principal Investigator |
FUJII Masaaki 東京工業大学, ソリューション研究機構, 教授 (60181319)
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Co-Investigator(Kenkyū-buntansha) |
SAKAI Makoto 東京工業大学, 資源化学研究所, 准教授 (60298172)
ISHIUCHI Shun-ichi 東京工業大学, 資源化学研究所, 助教 (40338257)
HASHIMOTO Kenro 首都大学東京, 理工学研究科, 准教授 (40202254)
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Co-Investigator(Renkei-kenkyūsha) |
MISAWA Kentaro 東京工業大学, 資源化学研究所, 特任助教 (10431991)
MIYAZAKI Mitsuhiko 東京工業大学, 資源化学研究所, 助教 (00378598)
|
Project Period (FY) |
2007 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥83,300,000 (Direct Cost: ¥83,300,000)
Fiscal Year 2011: ¥6,800,000 (Direct Cost: ¥6,800,000)
Fiscal Year 2010: ¥8,500,000 (Direct Cost: ¥8,500,000)
Fiscal Year 2009: ¥12,700,000 (Direct Cost: ¥12,700,000)
Fiscal Year 2008: ¥27,500,000 (Direct Cost: ¥27,500,000)
Fiscal Year 2007: ¥27,800,000 (Direct Cost: ¥27,800,000)
|
Keywords | 生体関連分子 / レーザー分光 / レーザー蒸発法 / 超音速ジェット / 赤外分光 / 時間分解分光 / 質量分析 / 液体噴霧法 / 発光分析 / 超音ジェット |
Research Abstract |
Various materials to increase the efficiency of laser desorption of nonvolatile biomolecules were explored. Gold nano particle and carbon black were concluded as the best materials. The development enables us to determine structures of catecholamines and related molecules systematically by their UV and IR spectra. Picosecond time-resolved IR spectroscopy was applied to ionization triggered water migration dynamics in acetanilide-water system. This revealed details of the dynamics of single water molecule from the molecular point of view for the first time. Vibrational sum-frequency generation and optical microscope were combined to develop an IR super-resolution microscopy. 14 times higher spatial resolution than the IR diffraction limit was achieved and internal structures of cells were successfully visualized.
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Report
(7 results)
Research Products
(202 results)
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[Journal Article] A Hybrid Data Base : Quantum Chemistry Literature Data Base II-New Concept and New Technology-2010
Author(s)
Keiko Takano, Nobuaki Koga, Toshio Matsushita, Kenro Hashimoto, Haruo Hosoya, Hidenori Matsuzawa, Umpei Nagashima, Takeshi Nishikawa, Hiroaki Wasada, Shinichi Yamaba, Masanori Tachikawa, Masahiko Hada
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Journal Title
Bulletin of the Chemical Society of Japan
Volume: 83
Pages: 660-666
Related Report
Peer Reviewed
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[Journal Article] Plugging a Molecular Wire into Photosystem I for Reconstitution of the Photoelectric Conversion System on a Gold Electrode2009
Author(s)
N.Terasaki, N.Yamamoto, T.Hiraga, Y.Yamanoi, T.Yonezawa, H.Nishihara, T.Ohmori, M.Sakai, M.Fujii, A.Tohri, M.Iwai, I.Enami, Y.Inoue, S.Yonezawa, M.Minakata
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Journal Title
Angewandte Chemie International Edition 48
Pages: 1585-1587
Related Report
Peer Reviewed
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[Journal Article] Real-time and Direct Analysis of Pollutants in Exhaust Gas Utilizing Resonance Enhanced multi-photon ionization (2)-Variations of Emissions Under Test Driving Modes?dispersed fluorescence spectroscopies2008
Author(s)
K. Misawa, J. Matsumoto, Y. Yamato, S. Mae, S. Ishiuchi, M. Fujii, K. Tanaka, T. Suzuki, S. Hayashi, H. Yamada, Y. Goto
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Journal Title
Review of Automotive Engineering 29
Pages: 123-125
Related Report
Peer Reviewed
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[Presentation] Photoionization-induced π→H isomerization of PhOH-CH4 cluster studied by REMPI, MATI and REMPI-IR spectroscopies2008
Author(s)
A. Takeda, M. Miyazaki, S. Ishi,uchi, M. Sakai, M. Fujii, A. Armentano, M. Benyezzar, X. Tong, K. Miiller-dethlefs
Organizer
Gordon Research Conference:Molecular and Ionic clusters 2008
Place of Presentation
Aussois, France
Related Report
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