| Budget Amount *help |
¥33,300,000 (Direct Cost: ¥33,300,000)
Fiscal Year 2011: ¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2010: ¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2009: ¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2008: ¥10,000,000 (Direct Cost: ¥10,000,000)
Fiscal Year 2007: ¥13,400,000 (Direct Cost: ¥13,400,000)
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| Research Abstract |
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry allows us to know molecular weight of compounds. Although sample preparation and operation of instruments are quite easy compared with other soft ionization methods, there are several drawbacks at the same time. In the study, we investigated desorption and ionization mechanisms by spectroscopic methods, and we developed useful techniques to overcome such drawbacks in MALDI.
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