| Budget Amount *help |
¥198,000,000 (Direct Cost: ¥198,000,000)
Fiscal Year 2011: ¥39,600,000 (Direct Cost: ¥39,600,000)
Fiscal Year 2010: ¥39,600,000 (Direct Cost: ¥39,600,000)
Fiscal Year 2009: ¥39,600,000 (Direct Cost: ¥39,600,000)
Fiscal Year 2008: ¥39,600,000 (Direct Cost: ¥39,600,000)
Fiscal Year 2007: ¥39,600,000 (Direct Cost: ¥39,600,000)
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| Research Abstract |
We have revealed the mechanisms of various aspects of protein transport into mitochondria, including cooperation of translocators, driving force for protein translocation, roles of multiple targeting signals in the presequence, mapping of subunit arrangements in the translocator complex, assembly of β-barrel proteins etc. We have also revealed the mechanisms of protein quality control in the ER, including roles of interactions between Mnl1 and PDI, ER retention of aberrant proteins by Yos9, roles of Hsp70 in plant sexual reproduction etc.
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