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Peroxisome biogenesis and regulation

Planned Research

Project AreaProtein community: organization and maintenance of protein functions
Project/Area Number 19058011
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionKyushu University

Principal Investigator

FUJIKI Yukio  九州大学, 大学院・理学研究院, 教授 (70261237)

Co-Investigator(Kenkyū-buntansha) TAMURA Shigehiko  九州大学, 大学院・理学研究院, 准教授 (90236753)
OKUMOTO Kanji  九州大学, 大学院・理学研究院, 助教 (20363319)
Project Period (FY) 2007 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥63,500,000 (Direct Cost: ¥63,500,000)
Fiscal Year 2011: ¥12,700,000 (Direct Cost: ¥12,700,000)
Fiscal Year 2010: ¥12,700,000 (Direct Cost: ¥12,700,000)
Fiscal Year 2009: ¥12,700,000 (Direct Cost: ¥12,700,000)
Fiscal Year 2008: ¥12,700,000 (Direct Cost: ¥12,700,000)
Fiscal Year 2007: ¥12,700,000 (Direct Cost: ¥12,700,000)
Keywordsペルオキシソームの形成機構 / CHO 変異細胞 / ペルオキシン / Pex5p リサイクル / ユビキチン化 / ペルオキシソームの分裂と形態制御 / DHA / 品質管理 / ペルオキシソーム / CHO変異細胞 / Pex5p エクスポート / Tysnd1, PsLon / AAA ATPase / レドソクスポテンシャル / PPAR / ペルオキシソーム形成因子 / ペルオキシソーム欠損症 / 膜形成 / ペルオキソーム欠損症 / ペルオキシソーム膜形成 / ペルオキシソームの形機構 / ペルオキシソーム形態制御因子
Research Abstract

Our representative findings include 1) peroxisomal membrane is assembled by Pex3p, Pex16p and Pex19p; 2) in peroxisome-cytoplasmic shuttling of matrix protein transporter Pex5p, Cys-ubiquitination of Pex5p and soluble factor AWP1 are essential for the Pex5p exit.

Report

(7 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (257 results)

All 2012 2011 2010 2009 2008 2007 Other

All Journal Article (65 results) (of which Peer Reviewed: 63 results) Presentation (184 results) Book (4 results) Remarks (4 results)

  • [Journal Article] Ligand-dependent nucleo-cytoplasmic shuttling of peroxisome proliferators-activated receptors, PPARα and PPARγ2012

    • Author(s)
      Umemoto, T., and Fujiki, Y.
    • Journal Title

      Genes Cells

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Peroxisome biogenesis disorders: molecular basis for impaired peroxisomal membrane assembly2012

    • Author(s)
      Fujiki, Y., Yagita, Y., and Matsuzaki, T.
    • Journal Title

      Biochim. Biophys. Acta- Mol. Basis Dis.

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome and rhizomelic chondrodysplasia punctata2012

    • Author(s)
      Kanzawa, N., Shimozawa, N., Wanders, R.J.A., Ikeda, K., Murakami, Y., Waterham, H.R., Mukai, S., Fujita, M., Maeda, Y., Taguchi, R., Fujiki, Y., and Kinoshita, T.
    • Journal Title

      J. Lipid Res.

      Volume: 53 Pages: 653-663

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division2012

    • Author(s)
      Itoyama, A., Honsho, M., Abe, Y., Moser, A., Yoshida, Y., and Fujiki, Y.
    • Journal Title

      J. Cell Sci.

      Volume: 125 Pages: 589-602

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] AWP1/ZFAND6 functions in Pex5 export by interacting with Cys-monoubiquitinated Pex5 and Pex6 AAA ATPase2012

    • Author(s)
      Miyata, N., Okumoto, K., Noguchi, M., Mukai, S., and Fujiki, Y.
    • Journal Title

      Traffic

      Volume: 13 Pages: 168-183

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] New insights into dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p in shuttling of PTS1-receptor Pex5p during peroxisome biogenesis2012

    • Author(s)
      Fujiki, Y., Nashiro, C., Miyata, N., Tamura, S., Okumoto, K.
    • Journal Title

      Biochim. Biophys. Acta- Mol. Cell Biol.

      Volume: 1823 Pages: 145-149

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] New insights into dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p in shuttling of PTS1-receptor Pex5p during peroxisome biogenesis2012

    • Author(s)
      Fujiki, Y., et al.
    • Journal Title

      Biochimica et Biophysica Acta-Molecular Cell Research

      Volume: 1823 Issue: 1 Pages: 145-149

    • DOI

      10.1016/j.bbamcr.2011.10.012

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase2012

    • Author(s)
      Miyata N, Okumoto K, Mukai S, Noguchi M, Fujiki Y.
    • Journal Title

      Traffic

      Volume: 13 Issue: 1 Pages: 168-183

    • DOI

      10.1111/j.1600-0854.2011.01298.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division2012

    • Author(s)
      Itoyama, A., et al.
    • Journal Title

      Journal of Cell Science

      Volume: 125 Issue: 3 Pages: 589-602

    • DOI

      10.1242/jcs.087452

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome and rhizomelic chondrodysplasia punctata2012

    • Author(s)
      Kanzawa, N., et al.
    • Journal Title

      Journal of Lipid Research

      Volume: 53 Issue: 4 Pages: 653-663

    • DOI

      10.1194/jlr.m021204

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Peroxisome biogenesis disorders : molecular basis for impaired peroxisomal membrane assembly2012

    • Author(s)
      Fujiki, Y., et al.
    • Journal Title

      Biochimica et Biophysica Acta- Molecular Basis of Disease

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ligand-dependent nucleo-cytoplasmic shuttling of peroxisome proliferato rs-activated receptors, PPARα and PPARγ2012

    • Author(s)
      Umemoto, T., et al.
    • Journal Title

      Genes to Cells

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two proteases, Tysnd1 and PsLon, cooperatively regulate fatty-acid β-oxidation in the peroxisomal matrix2011

    • Author(s)
      Okumoto, K., Kametani, Y., and Fujiki, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Pages: 44367-44379

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] ペルオキシソームの形成・制御の分子基盤2011

    • Author(s)
      藤木幸夫, 糸山彰徳, 奥本寛治
    • Journal Title

      細胞工学11 月号特集「オルガネラモデリング- ベールを脱ぐ分子設計」

      Volume: 30 Pages: 1153-1159

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells2011

    • Author(s)
      Yonekawa, S., Furuno, A., Baba, T., Fujiki, Y., Ogasawara, Y., Yamamoto, A., Tagaya, M., and Tani, K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 108 Pages: 12746-12751

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cysteine- ubiquitination of peroxisome- targeting-signal type1 (PTS1)- receptor Pex5p regulates Pex5p recycling.2011

    • Author(s)
      Okumoto, K., Misono, S., Miyata, N., Matsumoto, Y., Mukai, S., and Fujiki, Y.
    • Journal Title

      Traffic

      Volume: 12 Pages: 1067-1083

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recruiting mechanism of the AAA peroxins, Pex1p and Pex6p, to Pex26p on peroxisome membrane.2011

    • Author(s)
      Nashiro, C., Kashiwagi, A., Matsuzaki, T., Tamura, S., and Fujiki, Y.
    • Journal Title

      Traffic

      Volume: 12 Pages: 774-788

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear transport of peroxisome- proliferator activated receptor α.2011

    • Author(s)
      Iwamoto, F., Umemoto, T., Motojima, K., and Fujiki, Y.
    • Journal Title

      J. Biochem.

      Volume: 149 Pages: 311-319

    • NAID

      10030584027

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Interaction defect of the medium isoform of PTS1-receptor Pex5p with PTS2- receptor Pex7p abrogates the PTS2 protein import into peroxisomes in mammals.2011

    • Author(s)
      Honsho, M., Hashiguchi, Y., Ghaedi, K., and Fujiki Y.
    • Journal Title

      J. Biochem.

      Volume: 149 Pages: 203-210

    • NAID

      10030583515

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recruiting Mechanism of the AAA peroxins, Pex1p and Pex6p, to Pex26p on Peroxisome Membrane2011

    • Author(s)
      Nashiro, C., et al.
    • Journal Title

      Traffic

      Volume: 12 Issue: 6 Pages: 774-788

    • DOI

      10.1111/j.1600-0854.2011.01182.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cysteine-ubiquitination of peroxisome-targe ting-signal type 1 (PTS1)-receptor Pex5p regulates Pex5p recycling2011

    • Author(s)
      Okumoto, K., et al.
    • Journal Title

      Traffic

      Volume: 12 Issue: 8 Pages: 1067-1083

    • DOI

      10.1111/j.1600-0854.2011.01217.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells2011

    • Author(s)
      Yonekawa, S., et al.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 108 Issue: 31 Pages: 12746-12751

    • DOI

      10.1073/pnas.1103283108

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ペルオキシソームの形成・制御の分子基盤2011

    • Author(s)
      藤木幸夫, 他
    • Journal Title

      細胞工学11月号特集「オルガネラ・モデリング-ベールを脱ぐ分子設計図」

      Volume: 30 Pages: 1153-1159

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two proteases, Tysnd1 and PsLon, cooperatively regulate fatty-acid β-oxidation in the peroxisomal matrix2011

    • Author(s)
      Okumoto, K., et al.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 286 Issue: 52 Pages: 44367-44379

    • DOI

      10.1074/jbc.m111.285197

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction defect of the medium isoform of PTS1-receptor Pex5p with PTS2-receptor Pex7p abrogates the PTS2 protein import into peroxisomes in mammals2011

    • Author(s)
      Honsho, M., et al.
    • Journal Title

      Journal of Biochemistry

      Volume: 149 Pages: 203-210

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear transport of peroxisome-proliferator activated receptor α2011

    • Author(s)
      Iwamoto, F., et al.
    • Journal Title

      Journal of Biochemistry

      Volume: 149 Pages: 311-319

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recruiting Mechanism of the AAA peroxins, Pex1p and Pex6p, to Pex26p on peroxisome Membrane2011

    • Author(s)
      Nashiro, C., et al.
    • Journal Title

      Traffic

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ペルオキシソームの形成・制御とその障害による高次機能の破綻2010

    • Author(s)
      藤木幸夫, 宮田暖, 松園裕嗣, 松崎高志, 本庄雅則
    • Journal Title

      実験医学8 月号特集「Protein kinesis を解き明かすオルガネラの世界- 細胞機能の制御と遺伝病発症・ウイルス感染のメカニズム」

      Volume: 28 Pages: 2094-2101

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes.2010

    • Author(s)
      Yano, T., Oku, M., Akeyama, N., Itoyama, A., Yurimoto, H., Kuge, S., Fujiki, Y., and Sakai, Y.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 30 Pages: 3758-3766

    • NAID

      120002182833

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Monomerdimer transition of the consered N-terminal domain of the mammalian peroxisomal matrix protein import receptor, Pex14p.2010

    • Author(s)
      Su, J. R., Takeda, K., Tamura, S., Fujiki, Y., and Miki, K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 394 Pages: 217-221

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Posttranslational regulation of fatty Acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis.2010

    • Author(s)
      Honsho, M., Asaoku, S., and Fujiki, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 285 Pages: 8537-8542

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes2010

    • Author(s)
      Yano, T., et al.
    • Journal Title

      Molecular and Cellular Biology

      Volume: 30 Pages: 3758-3766

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ペルオキシソームの形成・制御とその障害による高次機能の破綻2010

    • Author(s)
      藤木幸夫, 他
    • Journal Title

      実験医学8月号 特集「Protein kinesisを解き明かすオルガネラの世界-細胞機能の制御と遺伝病発症・ウイルス感染のメカニズム」

      Volume: 28 Pages: 2094-2101

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Posttranslational regulation of fatty Acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis.2010

    • Author(s)
      Honsho, M., Asaoku, S., Fujiki, Y.
    • Journal Title

      J. Biol. Chem. 285(Paper of the Week)

      Pages: 8537-8542

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] monomer-dimer transition of the conserved N-terminal domain of the mammalian peroxisomal matrix protein import receptor, Pex14p2010

    • Author(s)
      Su, J.R., et al.
    • Journal Title

      Biochemical and Biophysical Research Communications 394

      Pages: 217-221

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Posttranslational regulation of fatty Acy1-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis2010

    • Author(s)
      Honsho, M., et al.
    • Journal Title

      The Journal of Biological Chemistry 285

      Pages: 8537-8542

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro import of peroxisome-targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes.2009

    • Author(s)
      Miyata, N., Hosoi, K., Mukai, S., and Fujiki, Y.
    • Journal Title

      Biochim. Biophys. Acta- Mol. Cell Res.

      Volume: 1793 Pages: 860-870

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Crystal struture of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pex14p.2009

    • Author(s)
      Su, J. R., Takeda, K., Tamura, S., Fujiki, Y., and Miki, K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 106 Pages: 417-421

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Crystal structure of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pex14p.2009

    • Author(s)
      Su, J.R., Takeda, K., Tamura, S., Fujiki, Y., Miki, K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 106

      Pages: 417-421

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] In vitro import of peroxisome-targeting signal type 2(PTS2) receptor Pex7p into peroxiosmes2009

    • Author(s)
      Miyata, N., et al.
    • Journal Title

      Biochimica et Biophysica Acta-Molecular Cell Research 1793

      Pages: 860-870

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystal structure of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pexl4p2009

    • Author(s)
      Su, J.-R., et.al.
    • Journal Title

      Proceedings of the National Academy of Sciences 106

      Pages: 417-421

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro import of peroxisome-targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes2009

    • Author(s)
      Miyata, N., et.al.
    • Journal Title

      Biochimica et Biophysica Acta - Molecular Cell Research (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The peroxisomal membrane-protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway.2008

    • Author(s)
      Matsuzaki, T., and Fujiki, Y.
    • Journal Title

      J. Cell Biol.

      Volume: 183 Pages: 1275-1286

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rcruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain.2008

    • Author(s)
      Chalupnikova, K., Lattmann, S., Selak, N., Iwamoto, F., Fujiki, Y., and Nagamine, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 283 Pages: 35186-35198

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes.2008

    • Author(s)
      Hara-Kuge, S., and Fujiki, Y.
    • Journal Title

      Exp. Cell Res.

      Volume: 314 Pages: 3531-3541

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and characterization of mutant animal cell line defective in alkyl-dihydroxyacetonephosphate synthase: Localization and transport of plasmalogens.2008

    • Author(s)
      Honsho, M., Yagita, Y., Kinoshita, N., and Fujiki, Y.
    • Journal Title

      Biochim. Biophys. Acta- Mol. Cell Res.

      Volume: 1783 Pages: 1857-1865

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and characterization of novel phenotype CHO cell mutants defective in peroxisome assembly, using ICR191 as a potent mutagenic agent.2008

    • Author(s)
      Ghaedi, K., and Fujiki. Y.
    • Journal Title

      Cell Biochem. Funct.

      Volume: 26 Pages: 684-691

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the interaction between recombinant human peroxin PEX3p and PEX19p: Identification of TRP104 in Pex3p as a critical residue for the interaction.2008

    • Author(s)
      Sato, Y., Shibata, H., Nakano, H., Matsuzono, Y., Yoshinori, K., Kobayashi, Y., Fujiki, Y., Imanaka, T., and Kato, H.
    • Journal Title

      J. Biol. Chem.

      Volume: 283 Pages: 6136-6144

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p involved in shuttling of the PTS1 receptor Pex5p in peroxisome biogenesis.2008

    • Author(s)
      Fujiki, Y., Miyata, N., Matsumoto, N., and Tamura, S.
    • Journal Title

      Biochem. Soc. Trans.

      Volume: 36 Pages: 109-113

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The peroxisomal membrane-protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway.2008

    • Author(s)
      Matsuzaki, T., Fujiki, Y.
    • Journal Title

      J. Cell Biol. 183

      Pages: 1275-1286

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes.2008

    • Author(s)
      Hara-Kuge, S., Fujiki, Y.
    • Journal Title

      Exp. Cell Res. 314

      Pages: 3531-3541

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Isolation and characterization of novel phenotype CHO cell mutants defective in peroxisome assembly, using ICR191 as a potent mutagenic agent2008

    • Author(s)
      Ghaedi, G., et.al.
    • Journal Title

      Cell Biochemistry and Function 26

      Pages: 684-691

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and characterization of mutant animal cell line defective in alkyl-dihydroxyacetonephosphate synthase: Localization and transport of plasmalogens to post-Golgi compartments2008

    • Author(s)
      Honsho, M., et.al.
    • Journal Title

      Biochimica et Biophysica Acta - Molecular Cell Research 1783

      Pages: 1857-1865

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The peroxin Pexl4p is involved in LC#-dependent degradation of mammalian proxisomes2008

    • Author(s)
      Hara-Kuge, S., et.al.
    • Journal Title

      Experimental Cell Research 314

      Pages: 3531-3541

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recruitment of the RNA helicase RHAU to stress franules via a unique RNA-binding domain2008

    • Author(s)
      Chalupnikova, K., et.al.
    • Journal Title

      The Journal of Biological Chemistry 283

      Pages: 35186-35198

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The peroxisomal membrane-protein import receptor Pex3p is directly transported to peroxisomes by a novel Pexl9p- and Pex16p-dependent pathway2008

    • Author(s)
      Matsuzaki, T., et.al.
    • Journal Title

      The Journal of Cell Biology 183

      Pages: 1275-1286

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ペルオキシソームの形成機構とその破綻2008

    • Author(s)
      藤木 幸夫
    • Journal Title

      膜 33

      Pages: 9-16

    • NAID

      10020130384

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic and functional assembly of the AAA peroxins, Pexlp and Pex6P their membrane receptor Pex26p involved in stuttling of the PTS1 receptor Pex5p in peroxisome biogenesis2008

    • Author(s)
      Fujiki, Y, et. al.
    • Journal Title

      Biochemistry Society Transduction 36

      Pages: 109-113

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the interaction between recombinant human peroxin PEX3p and PEX19p: Identification of IRP 104 in Pex3p as a critical residue for the interaction2008

    • Author(s)
      Sato, Y, et. al.
    • Journal Title

      Journal of Biological Chemistry 283

      Pages: 6136-6144

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and characterization of novel phenotype CHO cell mutants defective in peroxisome assembly, using ICR 191 as a potent mutagenic agent2008

    • Author(s)
      Ghaedi, K, et. al.
    • Journal Title

      Cell Biochemistry and Function (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alterations in the molecular species of plasmalogen phospholipids and glycolipids due to peroxisomal dysfunction in Chinese hamster ovary-mutant Z65 cells by FABMS method.2007

    • Author(s)
      Saito, M., Horikawa, M., Iwamori, Y., Sakakihara, Y., Mizuguchi, M., Igarashi, T., Fujiki, Y., and Iwamori, M.
    • Journal Title

      J. Chromatogr. B

      Volume: 852 Pages: 367-373

    • NAID

      10025802331

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis.2007

    • Author(s)
      Kobayashi, S., Tanaka, A., and Fujiki, Y.
    • Journal Title

      Exp. Cell Res.

      Volume: 313 Pages: 1675-1686

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis2007

    • Author(s)
      Kobayashi, S, et. al.
    • Journal Title

      Experimental Cell Research 313

      Pages: 1675-1686

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alterations in the molecular species of plasmalogen phospholipids and glycolipids due to peroxisomal dysfunction in Chinese hamster ovary-mutant Z65 cells by FABMS method2007

    • Author(s)
      Saito, M, et. al.
    • Journal Title

      Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 852

      Pages: 367-373

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ペルオキシソームの形成・分裂形態制御およびその轄害の分子基盤2007

    • Author(s)
      藤木 幸夫
    • Journal Title

      日本応用酵素協会誌 42

      Pages: 23-33

    • Related Report
      2007 Annual Research Report
  • [Presentation] Peroxisome : Biogenesis, Homeostasis, and Peroxisome Biogenesis Disorders2012

    • Author(s)
      藤木幸夫
    • Organizer
      The 7th KOREA-JAPAN Conference on Cellular Signaling for Young Scientists
    • Place of Presentation
      Ulsan, Korea(招待講演)
    • Year and Date
      2012-02-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Peroxisome: Biogenesis, Homeostasis, and Peroxisome Biogenesis Disorders2012

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 7th KOREA-JAPAN Conference on Cellular Signaling for Young Scientists
    • Place of Presentation
      韓国ウルサン市
    • Related Report
      2011 Final Research Report
  • [Presentation] ペルオキシソームのホメオスタシス:マトリクス酵素の調節とオルガネラ分解2011

    • Author(s)
      藤木幸夫, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)(招待講演)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] PTS1レセプターPex5pのペルオキシソーム-細胞質間リサイクリングはシステイン残基のユビキチン化修飾により制御される2011

    • Author(s)
      奥本寛治, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)(招待講演)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Pex16pによるペルオキシソーム分裂機構の解析2011

    • Author(s)
      向井悟, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] ユビキチンリガーゼP7BP1によるPTS2受容体Pex7pの品質管理機構の解明2011

    • Author(s)
      宮内康弘, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス精巣遺残体形成期におけるペルオキシソームの動態2011

    • Author(s)
      外山隆介, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソームC末アンカー蛋白質の生合成分子機構2011

    • Author(s)
      八木田悠一, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソーム分裂におけるDocosahexaenoic acidの機能解析2011

    • Author(s)
      糸山彰徳, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソーム形成因子Pex14pのリン酸化によるカタラーゼの細胞内局在化調節機構2011

    • Author(s)
      夏山竜一, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソーム膜タンパク質分裂機構の解析2011

    • Author(s)
      立道祐輝, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] A Novel Function of AWP1/ZFAND6^* Regulation of Pex5p Export by Interacting with Cys-monoubiquitinated Pex5p and AAA ATPase, Pex6p2011

    • Author(s)
      藤木幸夫, 他
    • Organizer
      2011 The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Denver, USA
    • Year and Date
      2011-12-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] P7BP1 E3 ubiquitin ligase controls the quality of PTS2 receptor, Pex7p2011

    • Author(s)
      宮内康弘, 他
    • Organizer
      2011 The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Denver, USA
    • Year and Date
      2011-12-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular Basis for Targeting of C-tail-anchored Proteins to Peroxisomes2011

    • Author(s)
      八木田悠一, 他
    • Organizer
      2011 The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Denver, USA
    • Year and Date
      2011-12-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Docosahexaenoic acid is required for peroxisomal elongation, a prerequisite for division of peroxisomes2011

    • Author(s)
      糸山彰徳, 他
    • Organizer
      2011 The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Denver, USA
    • Year and Date
      2011-12-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Novel Function of Peroxisome Targeting Signal Type-1 Receptor Pex5p in Pex14p Stability : Stucy Using a Newly Isolated Peroxisome-Deficient CHO Cell Mutant, ZPEG1012011

    • Author(s)
      夏山竜一, 他
    • Organizer
      2011 The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Denver, USA
    • Year and Date
      2011-12-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] A System to Quantify the Differential Import of Peroxisomal Matrix Protein by Measuring Fluorescence Intensity2011

    • Author(s)
      野口雅史, 他
    • Organizer
      2011 The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Denver, USA
    • Year and Date
      2011-12-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Peroxisome Homeostasis : Regulation of Plasmalogen Synthesis and Morphogenesis2011

    • Author(s)
      藤木幸夫, 他
    • Organizer
      International Symposium on New Aspects of Phospholipid Biology and Medicine 2011
    • Place of Presentation
      ザ・ルイガンズ(福岡)(招待講演)
    • Year and Date
      2011-11-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] AAA Peroxins, Pex1p and Pex6p, and Their Recruiter Pex26p Modulate the Peroxisomal Targeting Signal 1 (PTS1) Receptor Pex5p in Peroxisomal Protein Import2011

    • Author(s)
      藤木幸夫
    • Organizer
      9th International Conference on AAA Proteins
    • Place of Presentation
      熊本市国際交流会館(熊本)(招待講演)
    • Year and Date
      2011-11-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] AAA peroxins and their recruiter Pex26p modulate the peroxin interactions involved in peroxisomal protein import2011

    • Author(s)
      田村茂彦, 他
    • Organizer
      9th International Conference on AAA Proteins
    • Place of Presentation
      熊本市国際交流会館(熊本)
    • Year and Date
      2011-11-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Recruiting Mechanism of the AAA Peroxins, Pex1p and Pex6p, to Pex26d on Peroxisomal Membrane2011

    • Author(s)
      名城千香, 他
    • Organizer
      9th International Conference on AAA Proteins
    • Place of Presentation
      熊本市国際交流会館(熊本)
    • Year and Date
      2011-11-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソームの形成と障害およびホメオスタシスの分子機構2011

    • Author(s)
      藤木幸夫
    • Organizer
      千里ライフサイエンスセミナー「生命科学を支えるオルガネラ研究の新展開」
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2011-09-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソームの形成と障害およびホメオスタシス2011

    • Author(s)
      藤木幸夫
    • Organizer
      第35回蛋白質と酵素の構造と機能に関する九州シンポジウム
    • Place of Presentation
      志賀島国民休暇村(福岡)
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナンセンス変異の抑制によるペルオキシソーム障害の回復メカニズム2011

    • Author(s)
      田村茂彦, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2011-09-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソーム分解に関与するPex14およびp62の相互作用2011

    • Author(s)
      久下小百合, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2011-09-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソームのホメオスタシス:タンパク質インポートおよび形態の調節2011

    • Author(s)
      藤木幸夫, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館(京都)(招待講演)
    • Year and Date
      2011-09-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] エーテルリン脂質プラスマローゲンの生合成を制御するFatty acyl-CoA reductase 1の活性制御にはペルオキシソーム膜タンパク質が関与する2011

    • Author(s)
      本庄雅則, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 細胞全蛍光量測定によるペルオキシソームマトリクスタンパク質輸送効率測定法2011

    • Author(s)
      野口雅史, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2011-08-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソームの形成制御:細胞生物学、生理学と蛋白質科学のインターフェイス2011

    • Author(s)
      藤木幸夫
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪)(招待講演)
    • Year and Date
      2011-06-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] BN-PAGEによるペルオキシン複合体の解析2011

    • Author(s)
      田村茂彦, 他
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪)
    • Year and Date
      2011-06-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] PTS1レセプターPex5pのユビキチン化修飾によるペルオキシソームマトリクスタンパク質輸送の制御2011

    • Author(s)
      奥本寛治, 他
    • Organizer
      平成23年度日本生化学会九州支部例会
    • Place of Presentation
      久留米大学筑水会館(福岡)
    • Year and Date
      2011-05-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソーム膜上のPex26pに対するAAA-ATPaseペルオキシン、Pex1pとPex6pの局在化機構2011

    • Author(s)
      名城千香, 他
    • Organizer
      平成23年度日本生化学会九州支部例会
    • Place of Presentation
      久留米大学筑水会館(福岡)
    • Year and Date
      2011-05-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Pex14p directly interacts with LC3-II via its transmembrane domain to initiate peroxisomal degradation in mammalian cells2011

    • Author(s)
      蒋李, 他
    • Organizer
      平成23年度日本生化学会九州支部例会
    • Place of Presentation
      久留米大学筑水会館(福岡)
    • Year and Date
      2011-05-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペルオキシソームおホメオスタシス:マトリクス酵素の調節とオルガネラ分解2011

    • Author(s)
      藤木幸夫, 山下俊一, 久下小百合, 奥本寛治
    • Organizer
      第34 回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Final Research Report
  • [Presentation] AAA peroxins, Pex1p and Pex6p, and Their Recruiter Pex26p Modulate the Peroxisomal Targeting Signal 1 (PTS1) Receptor Pex5p in Peroxisomal Protein Import.2011

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 9th International Conference on AAA Proteins
    • Place of Presentation
      熊本市
    • Related Report
      2011 Final Research Report
  • [Presentation] ペルオキシソームのホメオスタシス:タンパク質インポートおよび形態の調節2011

    • Author(s)
      藤木幸夫, 宮田暖, 糸山彰徳, 奥本寛治
    • Organizer
      第84 回日本生化学会大会
    • Place of Presentation
      京都市
    • Related Report
      2011 Final Research Report
  • [Presentation] ペルオキシソーム膜タンパク質過剰発現によって誘導されるペルオキシソーム分解経路2011

    • Author(s)
      山下俊一, 他
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Pexllp mediates peroxisomal proliferation in living cells2011

    • Author(s)
      吉田祐美, 他
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2011 Annual Research Report
  • [Presentation] The interaction between the transmembrane domain of Pex14p and LC3-II is inhibited by Pex5p2011

    • Author(s)
      蒋李, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館(京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Peroxisome biogenesis: membrane assembly and matrix protein import - Lessons from different species2010

    • Author(s)
      藤木幸夫
    • Organizer
      第33 回日本分子生物学会年会・第83 回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome: biogenesis and homeostasis - membrane assembly, matrix protein import, morphogenesis, and turnover2010

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      奈良市
    • Related Report
      2011 Final Research Report
  • [Presentation] 細胞内小器官ペルオキシソームの形成・障害・ホメオスタシス2010

    • Author(s)
      藤木幸夫
    • Organizer
      平成22 年度日本生化学会中国・四国支部会例会
    • Place of Presentation
      山口市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisomal import of matrix and membrane proteins2010

    • Author(s)
      Yukio Fujiki
    • Organizer
      Gordon Research Conferences: Protein transport across cell membranes
    • Place of Presentation
      米国ガルベストン市
    • Related Report
      2011 Final Research Report
  • [Presentation] 細胞内小器官ペルオキシソームの形成・制御・ホメオスタシス2010

    • Author(s)
      藤木幸夫
    • Organizer
      平成22年度日本生化学会中国・四国支部例会
    • Place of Presentation
      山口市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規ペルオキシソーム膜タンパク質TMEM135/PMP52の機能解析2010

    • Author(s)
      奥本寛治, 他
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      大阪市
    • Related Report
      2010 Annual Research Report
  • [Presentation] セミインタクト細胞を用いたペルオキシソーム移行シグナル2型(PTS2)-タンパク質の輸送機構解析2010

    • Author(s)
      向井悟, 他
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      大阪市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新たな相補性群に属するペルオキシソーム欠損性変異細胞の解析2010

    • Author(s)
      細井謙一郎, 他
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      大阪市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Peroxisome : biogenesis and homeostasis-membrane assembly, matrix protein import, morphogenesis, and turnover2010

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Restoration of peroxisome biogenesis in peroxisome-deficient cells with a nonsense suppressor compound (G418)2010

    • Author(s)
      Shigehiko Tamura, et al.
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional roles of two serine proteases, Tysnd1 and PsLon, in peroxisome matrix2010

    • Author(s)
      Kanji Okumoto, et al.
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Turnover mechanism of the PTS2 import receptor, Pex7p2010

    • Author(s)
      Yasuhiro Miyauchi, et al.
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Peroxisome degradation in mammalian cells2010

    • Author(s)
      Shun-ichi Yamashita, et al.
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Biogenesis of peroxisomal C-tail-anchored proteins2010

    • Author(s)
      Yuichi Yagita, et al.
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Docosahexaenoic acid is required for peroxisomal elongation, a prerequisite for division of peroxisomes2010

    • Author(s)
      Akinori Itoyama, et al.
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] A system to quantify the differential import of peroxisomal matrix peroteins by measuring fluorescence intensity2010

    • Author(s)
      Masafumi Noguchi, et al.
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Peroxisome biogenesis : membrane assembly and matrix protein import-Lessons from different species2010

    • Author(s)
      藤木幸夫
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] AAAペルオキシンとPex26pによって制御されるペルオキシン相互作用2010

    • Author(s)
      田村茂彦, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 多価不飽和脂肪酸を有するプラスマローゲンによるプラスマローゲン生合成調節2010

    • Author(s)
      本庄雅則, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] ペルオキシソームの形成機構:PTS2受容体Pex7pの細胞内分解機構の解明2010

    • Author(s)
      宮内康弘, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] ペルオキシソーム分解におけるp62、LC3およびPex14pのタンパク質修飾依存的相互作用2010

    • Author(s)
      久下小百合, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Lipidomics of peroxisome-deficient Chinese hamster ovary cells and fibroblasts from patients with Zellweger syndrome2010

    • Author(s)
      阿部雄一, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 哺乳類培養細胞におけるペルオキシソーム分解の検出2010

    • Author(s)
      山下俊一, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pex11p mediates peroxisomal proliferation in living cells2010

    • Author(s)
      吉田祐美, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] ペルオキシソームC末アンカー蛋白質の輸送機構2010

    • Author(s)
      八木田悠一, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Docosahexaenoic acidはペルオキシソーム分裂の初期段階である伸長化に機能する2010

    • Author(s)
      糸山彰徳, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] PTS1レセプター遺伝子PEX5欠損性新規CHO変異細胞ZPEG101の分離と解析2010

    • Author(s)
      夏山竜一, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 細胞全蛍光量測定によるペルオキシソームマトリクスタンパク質輸送効率測定法2010

    • Author(s)
      野口雅史, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 細胞内ペルオキシソーム移動へのペルオキシソーム局在性タンパク質U30BP1の役割2010

    • Author(s)
      小野立晃, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 核内受容体PPARγの核-細胞質間輸送調節による機能制御機構の解明2010

    • Author(s)
      齊藤誠, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] ペルオキシソーム形成におけるPex5p-Pex14p相互作用の定量的解析2010

    • Author(s)
      竹場亮太, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] ペルオキシソーム分裂におけるMitochondrial fission factor(Mff)の機能解析2010

    • Author(s)
      道行悟, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pexophagy in mammalian cells : the peroxin Pex14p directly interacts with LC3-II in vitro2010

    • Author(s)
      蒋李, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] ペルオキシソーム病におけるGPIアンカー生合成異常の病因的意義の解明2010

    • Author(s)
      神澤範行, 他
    • Organizer
      第33回日本分子生物学会年会・第82回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Peroxisomal import of matrix and membrane proteins.2010

    • Author(s)
      Yukio Fujiki
    • Organizer
      Gordon Research Conferences: Protein transport across cell membranes
    • Place of Presentation
      Galveston, USA
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] ペルオキシソームの創成とその制御機構2009

    • Author(s)
      藤木幸夫
    • Organizer
      第32 回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome biogenesis and its regulation: membrane assembly, matrix protein import, and morphogenesis2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      米国シアトル市
    • Related Report
      2011 Final Research Report
  • [Presentation] ペルオキシソーム形成におけるPex5p のダイナミズムとその制御システム2009

    • Author(s)
      田村茂彦
    • Organizer
      第82 回日本生化学会大会
    • Place of Presentation
      神戸市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome biogenesis and Its Dysfunctions: Membrane Assembly, Matrix Protein Import, and Morphogenesis2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 4^<th> International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      札幌市
    • Related Report
      2011 Final Research Report
  • [Presentation] Degradation of Mammalian Peroxisomes2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 5^<th> International Symposium on Autophagy
    • Place of Presentation
      大津市
    • Related Report
      2011 Final Research Report
  • [Presentation] Dynamic and functional assembly of the AAA Peroxins, Pex1p and Pex6p, and their interacting partners in peroxisome biogenesis2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      8^<th> International Conference on AAA Proteins
    • Place of Presentation
      カナダトロント市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome Biogenesis: Mechanistic insights to protein import and its regulation2009

    • Author(s)
      藤木幸夫
    • Organizer
      第61 回日本細胞生物学会大会
    • Place of Presentation
      名古屋市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome biosynthesis and its regulation: membrane assembly, matrix protein import, and morphogenesis.2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      Seattle, USA
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] エーテルリン脂質プラスマローゲンの生合成調節機構2009

    • Author(s)
      本庄雅則, 他
    • Organizer
      平成21年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソームマトリクスに局在するセリンプロテアーゼTysnd1の機能解析2009

    • Author(s)
      奥本寛治, 他
    • Organizer
      平成21年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Docosahezaenoic acid(DHA)によるペルオキシソーム形態異常の回復2009

    • Author(s)
      糸山彰徳, 他
    • Organizer
      平成21年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規PEX5欠損性CHO変異細胞ZPEG101の分離と解析2009

    • Author(s)
      夏山竜一, 他
    • Organizer
      平成21年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソーム病とPex1p, Pex6p2009

    • Author(s)
      田村茂彦, 他
    • Organizer
      第9回日本蛋白質科学会年会
    • Place of Presentation
      熊本市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Peroxisome Biogenesis : Mechanistic insights to protein import and its regulation2009

    • Author(s)
      藤木幸夫, 他
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋市
    • Related Report
      2009 Annual Research Report
  • [Presentation] RING peroxin complex of Pex10p and Pex12p ubiquitinates the PTS1 receptor Pex5p and regulates its shuttling between peroxisomes and the cytosol2009

    • Author(s)
      奥本寛治, 他
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Mechanistic insights into peroxisomal protein import via peroxisome targeting signal receptors, using an in vitro translocation system2009

    • Author(s)
      宮田暖, 他
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Docosahexaenoic acid restores morphologically aberrant peroxisomes in a Pex11p-dependent manner2009

    • Author(s)
      糸山彰徳, 他
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Dynamic and functional assembly of the AAA Peroxins, Pex1p and Pex6p, and their interacting partners in peroxisome biogenesis2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      8^<th> International Conference on AAA Proteins
    • Place of Presentation
      Toronto, Canada
    • Related Report
      2009 Annual Research Report
  • [Presentation] Degradation of Mammalian Peroxisomes2009

    • Author(s)
      Yukio Fujiki, et al.
    • Organizer
      The 5^<th> International Symposium on Autophagy
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Peroxisome homeostasis in autophagy-defective cells2009

    • Author(s)
      Shun-ichi Yamashita, et al.
    • Organizer
      The 5^<th> International Symposium on Autophagy
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Peroxisome biogenesis and Its Dysfunctions : Membrane Assembly, matrix Protein Import, and Morphogenesis2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 4^<th> International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Sapporo, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソーム形成におけるPex5pのダイナミズムとその制御システム2009

    • Author(s)
      田村茂彦, 他
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸市
    • Related Report
      2009 Annual Research Report
  • [Presentation] エーテルリン脂質プラスマローゲンの生合成調節機構2009

    • Author(s)
      本庄雅則, 他
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸市
    • Related Report
      2009 Annual Research Report
  • [Presentation] P62、LC3およびPex14pの3者相互作用依存的なペルオキシソーム分解2009

    • Author(s)
      久下小百合, 他
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 細胞全蛍光量測定によるペルオキシソームマトリクスタンンパク室の膜透過輸送機構2009

    • Author(s)
      野口雅史, 他
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソームの形成:膜アセングリーとタンパク質の膜透過輸送機構2009

    • Author(s)
      藤木幸夫
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Peroxisome biogenesis and its regulation : membrane assembly, matrix protein import, and morphogenesis2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      Seattle, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Plasmalogen biosynthesis is regulated by modulating the protein level of fatty acyl-CoA reductase 1, Far1, not at a transcriptional level, in response to the cellular level of plasmalogens2009

    • Author(s)
      Masanori Honsho, et al.
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      Seattle, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] The complex of RING peroxins, Pex10p and Pex12p, ubiquitinates the PTS1 receptor Pex5p and regulates import of peroxisomal matrix proteins2009

    • Author(s)
      Kanji Okumoto, et al.
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      Seattle, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identifation of a novel cytosolic factor that regulates Pex5p export from peroxisomes2009

    • Author(s)
      Non Miyata, et al.
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      Seattle, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Docosahexaenoic acid restores morphologically aberrant peroxisomes2009

    • Author(s)
      Akinori Itoyama, et al.
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      Seattle, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] A system to quantify the import ration of peroxisomal matrix protein by measuring fluorescence intensity2009

    • Author(s)
      Masafumi Noguchi, et al.
    • Organizer
      International Meeting on Peroxisome Research
    • Place of Presentation
      Seattle, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Plasmalogen biosynthesis is regulated by modulating the protein level of fatty acyl-CoA reductase 1, Far1, not at a transcriptional level, in response to the cellular level of plasmalogens2009

    • Author(s)
      Masanori Honsho, et al.
    • Organizer
      The American Society for Cell biology 49^<th> Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソームの創成とその制御機構2009

    • Author(s)
      藤木幸夫
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] RINGペルオキシンPex10p/Pex12p複合体はPTS1レセプターPex5pのユビキチンリガーゼとして機能し、ペルオキシソームマトリクスタンパク質の輸送を制御する2009

    • Author(s)
      奥本寛治, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソーム膜形成障害生CHO細胞を用いたFis1のペルオキシソームおよびミトコンドリアへの輸送機構の解析2009

    • Author(s)
      松園裕嗣, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Peroxisome-targeting signal type 2(PTS2)-protein import in mammalian cells2009

    • Author(s)
      向井悟, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソームの形成制御機構:PTS2受容体Pex7pの細胞内分解機構と新たな機能解明2009

    • Author(s)
      宮内康弘, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 4-phenylbutyrateによるペルオキシソーム増殖の解析2009

    • Author(s)
      西野智則, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identification of a novel cytosolic factor that regulates Pex5p export from peroxisomes2009

    • Author(s)
      宮田暖, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規PEX5欠損性CHO変異細胞ZPEG101の分離と解析2009

    • Author(s)
      夏山竜一, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ナンセンス変異抑制によるペルオキシソーム欠損症患者由来線維芽細胞の障害回復2009

    • Author(s)
      中村博美, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] シャペロン用ペルオキシンタンパク質Pex19pを利用したペルオキシソーム膜タンパク質発現系の構築2009

    • Author(s)
      真津達巳, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソームの分裂・増殖に関わる因子の機能解析2009

    • Author(s)
      劉丹, 他
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Peroxisomal import of matrix and membrane proteins2009

    • Author(s)
      Yukio Fujiki
    • Organizer
      Gordon Research Conferences : Protein transport across cell membranes
    • Place of Presentation
      Galveston, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Newly identified Chinese hamster ovary cell mutants defective in peroxisome assembly represent one novel complementation group in mammals2009

    • Author(s)
      Kenichiro Hosoi, et al.
    • Organizer
      Gordon Research Conferences : Protein transport across cell membranes
    • Place of Presentation
      Galveston, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペルオキシソームの生合成:膜アセンブリーとマトリックスタンパク質輸送の分子基盤2008

    • Author(s)
      藤木幸夫
    • Organizer
      第31 回日本分子生物学会年会・第81 回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2011 Final Research Report
  • [Presentation] Roles of AAA peroxins and Pex26p in peroxisome biogenesis2008

    • Author(s)
      Shigehiko Tamura
    • Organizer
      Frontier of Organelle Dynamics and Protein Functions
    • Place of Presentation
      名古屋市
    • Related Report
      2011 Final Research Report
  • [Presentation] エーテルリン脂質プラスマローゲンの細胞内分布と輸送機構2008

    • Author(s)
      本庄雅則, 他
    • Organizer
      平成20年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソーム移行シグナル1型レセプターPex5pのドミナントネガティブ変異体の機能解析2008

    • Author(s)
      奥本寛治, 他
    • Organizer
      平成20年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソーム膜欠損性変異細胞を利用したペルオキシソーム膜生合成のメカニズム解析2008

    • Author(s)
      松園裕嗣, 他
    • Organizer
      平成20年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2008 Annual Research Report
  • [Presentation] AAA-ATPaseペルオキシンPexlpとPex6pのペルオキシソーム局在化機構2008

    • Author(s)
      名城千香, 他
    • Organizer
      平成20年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2008 Annual Research Report
  • [Presentation] FRB-FKBP二量体化システムを用いたペルオキシソームへのオリゴマータンパク質輸送の新規解析法2008

    • Author(s)
      野口雅史, 他
    • Organizer
      平成20年度日本生化学会九州支部例会
    • Place of Presentation
      福岡市
    • Related Report
      2008 Annual Research Report
  • [Presentation] AAA peroxins modulate the peroxin interactions in peroxisomal protein import2008

    • Author(s)
      田村茂彦, 他
    • Organizer
      第60回日本細胞生物学会大会
    • Place of Presentation
      横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Peroxisomal localization of a tail-anchored protein, Fatty acyl-CoA reductase2008

    • Author(s)
      本庄雅則, 他
    • Organizer
      第60回日本細胞生物学会大会
    • Place of Presentation
      横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Pex26p recruits Pexlp and Pex6p to peroxisomes in an ATP-dependent manner2008

    • Author(s)
      名城千香, 他
    • Organizer
      第60回日本細胞生物学会大会
    • Place of Presentation
      横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Novel method for peroxisomal import of oligomeric proteins using FRB and FKBP dimerization system2008

    • Author(s)
      野口雅史, 他
    • Organizer
      第60回日本細胞生物学会大会
    • Place of Presentation
      横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Peroxisome : Biogenesis, Biogenesis Disorders, Pathogenic Genes, and Restoration of Dysfunctions2008

    • Author(s)
      Yukio Fujiki
    • Organizer
      The 6^<th> Annual Congress of IDDST 2008
    • Place of Presentation
      Beijing, China
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソームの生合成 : 膜アセンブリーとマトリックスタンパク質輸送の分子基盤2008

    • Author(s)
      藤木幸夫
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] AAAペルオキシンPexlpによるペルオキシン相互作用の制御2008

    • Author(s)
      田村茂彦, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] プラスマローゲン合成を担うfatty acyl-CoArecuctase 1の機能制御2008

    • Author(s)
      本庄雅則, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソームマトリクスに局在する2種のセリンプロテアーゼ、PsLonとTysnd1の生理機能解析2008

    • Author(s)
      奥本寛治, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソーム膜形成障害性CHO細胞pex19ZP119を用いたペルオキシソーム膜タンパク質輸送および生合成機構の解明2008

    • Author(s)
      松園裕嗣, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソーム分裂・増殖因子Pexllpα-結合タンパク質の同定と解析2008

    • Author(s)
      向井悟, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会台同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] p62DLC3-およびPex14p-依存的ペルオキシソーム分解に関与する2008

    • Author(s)
      久下小百合, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソームの形成制御機構 : PTS2受容体Pex7pの細胞内分解機構と新たな機能の解明2008

    • Author(s)
      宮内康弘, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] In vitroインポート系を用いたペルオキシソームマトリクスタンパク質及びペルオキシソームターゲティングシグナル(PTS)受容体の分子機構の解析2008

    • Author(s)
      宮田暖, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Docosahexaenoic acid (DHA)によるペルオキシソーム形態異常の回復2008

    • Author(s)
      糸山彰徳, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ペルオキシソーム形成因子Pex26p欠損性CRO変異細胞とその障害の分子メカニズム2008

    • Author(s)
      肥和野康文, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 細胞内プラスマローゲン量に応答したfattyacyl-CoA reductase 1の分解に必要なドメインの探索2008

    • Author(s)
      福本恵子, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Crystal structure of the conserved N-terminal domain of Pexl4p2008

    • Author(s)
      蘇建栄, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Peroxisome Membrane Biogenesis : The Peroxisomal Membrane Transport Receptor Pex3p is Directly Inported Via Pexl6p in a Pexl9p-Dependent Manner2008

    • Author(s)
      Yukio Fujiki, et al.
    • Organizer
      The American Society for Cell Biology 48^<th> Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] Etherphospolipids, Plasmalogens are Transported via an ATP-dependent and Non-vesicular Pathway : Study with Plasmalogen deficient CHO Cell Mutant2008

    • Author(s)
      Yuichi Yagita, et al.
    • Organizer
      The American Society for Cell Biology 48th Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] Peroxisome Biogenesis and Dysfunction: Membrane Assembly, Matrix Protein Import, Morphogenesis, and Peroxisome Biogenesis Disorders2007

    • Author(s)
      藤木幸夫
    • Organizer
      第30 回日本分子生物学会年会・第80 回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Final Research Report
  • [Presentation] Dynamic and Functional Assembly of the AAA Peroxins, Pex1p and Pex6p, and Their Membrane Receptor Pex26p in Peroxisome Biogenesis2007

    • Author(s)
      Yukio Fujiki, Naomi Matsumoto, Shigehiko Tamura
    • Organizer
      The 7^<th> International AAA Proteins Conference
    • Place of Presentation
      イギリスサイレンセスター市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome Biogenesis: Matrix Protein Import, Membrane Assembly, Morphogenesis, and Peroxisome Assembly Disorders2007

    • Author(s)
      Yukio Fujiki
    • Organizer
      Gordon Research Conferences: Protein transport across cell membranes
    • Place of Presentation
      イタリアバルガ市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome Biogenesis: Membrane Assembly, Matrix Protein Import, Morphogenesis, and Peroxisome Assembly Disorders2007

    • Author(s)
      藤木幸夫
    • Organizer
      第40 回日本発生生物学会・第59 回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2011 Final Research Report
  • [Presentation] Peroxisome Biogenesis: Membrane Assembly, Matrix Protein Import, Morphogenesis, and Peroxisome Assembly Disorders2007

    • Author(s)
      藤木 幸夫
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Purification and characterization of the AAA peroxins, Pexlp and Pex6p2007

    • Author(s)
      田村 茂彦, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Isolation of plasmalogen-deficient cells2007

    • Author(s)
      本庄 雅則, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Novel function of peroisome targeting signal type-1 receptor Pex5p in Pex14p stability: stusy using a newly isolated peroxisome-deficient CHO mutant, ZPEG1012007

    • Author(s)
      奥本 寛治, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Degradation of peroxisomes in mammalian cells2007

    • Author(s)
      久下 小百合, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] The peroxisomal membrane transport receptor Pex3p is imported via Pex16p in a Pex19p-dependent manner2007

    • Author(s)
      松崎 高志, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Molecular mechanisms of import of peroxisome-targeting signal type 2(PTS2)-proteins by PTS2 receptor Pex7p and PTS1 receptor Pex5pL2007

    • Author(s)
      向井 悟, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Peroxisome biogenesis: Roles of clofibrate-inducible, novel rat PEX19 splicing variant2007

    • Author(s)
      木下 尚彦, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Pex19p functions as a chaperone and transports newly synthesized peroxisome membrane proteins in peroxisome biogenesis2007

    • Author(s)
      松園 裕嗣, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] The peroxin Pex26p: Domain mapping and Pex1p and Pex6p- regulated interaction with Pex14p2007

    • Author(s)
      松元 奈緒美, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis2007

    • Author(s)
      小林 慎太, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Mechanisms of targeting to peroxisomes of the AAA peroxins, Pex1p and Pex6p2007

    • Author(s)
      名城 千香, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] In vitro import of peroxisome targeting signal type 2(PTS2) receptor Pex7p into peroxisomes2007

    • Author(s)
      細井 謙一郎, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Establishing a model culture system for studying neuronal dysfunction in Zellweger syndrome2007

    • Author(s)
      藤原 一志郎, 他
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Peroxisome Biogenesis: Matrix Protein Import, Membrane Assembly, Morphogenesis, and Peroxisome Assembly Disorders2007

    • Author(s)
      Yukio, Fujiki
    • Organizer
      Gordon Research Conferences: Protein transport across cell membranes
    • Place of Presentation
      Barga, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] Dynamic and Functional Assembly of the AAA Peroxins, Pex1p and Pex6p, and Their Membrane Receptor Pex26p in Peroxisome Biogenesis2007

    • Author(s)
      Yukio, Fujiki, et. al.
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      Cirencester, UK
    • Related Report
      2007 Annual Research Report
  • [Presentation] Construction and Characterization of a Dominant-Negative Mutant of Peroxisome Targeting Signal Type-1 Receptor Pex5p2007

    • Author(s)
      Kanji, Okumoto, et. al.
    • Organizer
      The American Society for Cell Biology 47 th Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] Peroxisome Biogenesis and Dysfunctin: Membrane Assembly, Matrix Protein Import, Morphogenesis, and Peroxisome Biogenesis Disorders2007

    • Author(s)
      藤木 幸夫
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] AAAペルオキシンPexlpの細胞内局在およびN末端領域の機能解析2007

    • Author(s)
      田村 茂彦, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] プラスマローゲン合成を担うfatty acyl-CoA reductaseの機能解析2007

    • Author(s)
      本庄 雅則, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] ペルオキシソーム移行シグナル1型レセプターPex5pのドミナントネガティブ変異体を用いたペルオキシソームマトリクスタンパク質輸送機構の解析2007

    • Author(s)
      奥本 寛治, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] ペルオキシゾーム分解機構の解明2007

    • Author(s)
      久下 小百合, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] 培養肝細胞Faoを用いたペルオキシソーム分裂・増殖の分子機構解明2007

    • Author(s)
      向井 悟, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] ペルオキシソームの生合成:新規なクロフィブレート誘導性PEX19スプライシングバリアントの役割2007

    • Author(s)
      木下 尚彦, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] ペルオキシソーム膜欠損性CHO細胞pex19ZP119を用いたペルオキシソーム膜生合成機構の解明2007

    • Author(s)
      松園 裕嗣, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] AAA-ATPaseペルオキシンPex1pとPex6pの局在化の分子機構2007

    • Author(s)
      名城 千香, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] PTS2受容体Pex7pの輸送分子機構2007

    • Author(s)
      細井 謙一郎, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Fatty acyl-CoA reductase の細胞内局在および配向性2007

    • Author(s)
      麻奥 俊介, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] ペルオキシソーム増殖の分子機構:4-Phenyl butyrateを用いた解析2007

    • Author(s)
      上川 夏代, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] ペルオキシソーム局在型Lonプロテアーゼの生理機能解析2007

    • Author(s)
      亀谷 紫, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] 神経形成異常を呈するZellweger症候群のモデル培養細胞系の確立と形態学的検討2007

    • Author(s)
      川口 怜子, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] LC3-II-Pex14p間相互作用の分子機構2007

    • Author(s)
      西村 枝里子, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] ペルオキシソームおよびミトコンドリア分裂制御因子ダイナミン様タンパク質1(Dynamin-Like Protein 1)の機能領域解析2007

    • Author(s)
      山本 泰三, 他
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Book] "Peroxisome Biogenesis Disorders" In : Encyclopedia of the Life Sciences2011

    • Author(s)
      Yukio Fujiki
    • Publisher
      John Wiley & Sons(on line)
    • Related Report
      2011 Annual Research Report
  • [Book] 生物薬科学実験講座5 細胞の構造とオルガネラ 第2章オルガネラ形成機構の研究法「ペルオキシソーム形成機構の研究法」pp.148-171, 大熊勝治/中西義信 編2010

    • Author(s)
      藤木幸夫
    • Publisher
      廣川書店
    • Related Report
      2011 Final Research Report
  • [Book] 大熊勝治/中西義信編生物薬科学実験講座5細胞の構造とオルガネラ第2章オルガネラ形成機構の研究法「ペルオキシソーム形成機構の研究法」148-1712010

    • Author(s)
      藤木幸夫
    • Total Pages
      271
    • Publisher
      廣川書店
    • Related Report
      2009 Annual Research Report
  • [Book] 小児科診療Vol.72増刊号小児の疾患群「Zellweger症候群」364-3652009

    • Author(s)
      藤木幸夫
    • Total Pages
      511
    • Publisher
      診断と治療社
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.biology.kyushu-u.ac.jp/~taisha/

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.biology.kyushu-u.ac.jp/~taisha/

    • Related Report
      2009 Self-evaluation Report
  • [Remarks]

    • URL

      http://www.biology.kyushu-u.ac.jp/~taisha/

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.biology.kyushu-u.ac.jp/~taisha/

    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2018-03-28  

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