Development of model systems for intrinsically disordered protein and understanding of the role of fluctuation on molecular recognition and folding

• Project Area: Molecular Science of Fluctuations toward Biological Functions
• Project/Area Number: 20107006
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Nara Institute of Science and Technology
• Principal Investigator: KATAOKA Mikio 奈良先端科学技術大学院大学, 物質創成科学研究科, 教授 (30150254)
• Co-Investigator(Renkei-kenkyūsha): KAMIKUBO Hironari 奈良先端科学技術大学院大学, 物質創成科学研究科, 准教授 (20311128) ; YAMAZAKI Yoichi 奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (40332770) ; YAMAGUCHI Mariko 奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (50521738) ; SHIBA Rumi 奈良先端科学技術大学院大学, 物質創成科学研究科, 博士研究員 (70617133) ; ENDO Hitoshi 日本原子力研究開発機構, 量子ビーム応用研究部門, 研究員 (40447313)
• Project Period (FY): 2008 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥126,620,000 (Direct Cost: ¥97,400,000、Indirect Cost: ¥29,220,000); Fiscal Year 2012: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000); Fiscal Year 2011: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000); Fiscal Year 2010: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000); Fiscal Year 2009: ¥22,360,000 (Direct Cost: ¥17,200,000、Indirect Cost: ¥5,160,000); Fiscal Year 2008: ¥35,750,000 (Direct Cost: ¥27,500,000、Indirect Cost: ¥8,250,000)
• Keywords: 天然変性蛋白質 / 誘導折り畳み / 分子認識 / 変性構造 / 結晶構造解析 / Staphylococcal nuclease / 天然変性タンパク質 / FRET / X線結晶構造解析 / 核酸分解酵素 / 揺らぎ / トリプトファン三重項 / 中性子散乱 / ストップトフローCD / 黄色ブドウ球菌核酸分解酵素 / 中性子非弾性散乱 / 水和水 / 標的結合 / タンパク質動力学

Research Abstract

We created various mutants of functional proteins which do not take stable native conformations but possess enzymatic activity as well as the mutants which take native structure without enzymatic activity. The ligand-induced folding of the former mutants and the crystal structure analysis of the latter mutants brought the conclusion that fluctuations or structure dynamics facilitate the ligand recognition and that fluctuations controls the catalytic activity. We also revealed that the hydration water network via hydrogen bond encircled the protein whole molecule is essential for the control of fluctuations.

Research Products

• [Journal Article] Preferential domain orientation of HMGB2 determined by weak intramolecular interactions mediated by the interdomain linker (2013)
  • Author(s): J. Uewaki, H. Kamikubo, J. Kurita, N. Hiroguchi, H. Moriuchi, M. Yoshida, M. Kataoka, N. U.-Tate, S. Tate
  • Journal Title: Chem.Phys Volume: 419 Pages: 212-223
  • DOI: 10.1016/j.chemphys.2013.02.004
  • Peer Reviewed
• [Journal Article] Fingerprint signatures of lanthanide circularly polarized luminescence from proteins covalently labeled by a β -diketonate europium(III) chelate (2013)
  • Author(s): J.Yuasa, T. Ohno, H. Tsumatori, R. Shiba, H. Kamikubo, M. Kataoka, Y. Hasegawa, T. Kawai
  • Journal Title: Chem. Commn
  • Peer Reviewed
• [Journal Article] 働いているタンパク質の構造を実時間で見た!-次世代構造生物科学への期待 (2013)
  • Author(s): 上久保裕生,片岡幹雄
  • Journal Title: 化学 Volume: 68 Pages: 74-75
• [Journal Article] 働いているタンパク質の構造を実時間で見た！－次世代構造生物科学への期待 (2013)
  • Author(s): 上久保裕生
  • Journal Title: 化学 Volume: 68 Pages: 74-75
• [Journal Article] 1H, 13C, and 15N resonance assignment of photoactive yellow protein (2013)
  • Author(s): Trijntje J. Pool
  • Journal Title: Biomol. NMR Assign. Volume: 7 Pages: 97-100
  • Peer Reviewed
• [Journal Article] 1H, 13C, and 15N resonance assignment of photoactive yellow protein (2012)
  • Author(s): T. J. Pool, N. A. Oktaviani, H. Kamikubo, M. Kataoka, F. A. A. Mulder
  • Journal Title: Biomol. NMR Assign Volume: 7 Pages: 97-100
  • Peer Reviewed
• [Journal Article] Maintenance of the secondary structure ofhorse cytochrome c during the conversion process of monomers to oligomers byaddition of ethanol (2012)
  • Author(s): S. Hirota, M. Ueda, Y. Hayashi, S. Nagao, H. Kamikubo, M. Kataoka
  • Journal Title: J. Biochem Volume: 152 Pages: 521-529
  • Peer Reviewed
• [Journal Article] Time-resolved observation of chiral-index-selective wrapping on single-walled carbon nanotube with non-aromatic polysilane (2012)
  • Author(s): W. Chung, K. Nobusawa, H. Kamikubo, M. Kataoka, M. Fujiki, M. Naito
  • Journal Title: J. Am. Chem. Soc Volume: 135 Pages: 2374-2383
  • Peer Reviewed
• [Journal Article] Theoretical analysis of the geometrical isotope effect on the hydrogen bonds in photoactive yellow protein with multi-component density functional theory (2012)
  • Author(s): Y. Kita, H. Kamikubo, M. Kataoka, M. Tachikawa
  • Journal Title: Chem. Phys Volume: 419 Pages: 50-53
  • DOI: 10.1016/j.chemphys.2012.11.022
  • Peer Reviewed
• [Journal Article] Watching asignaling protein function in real time via100-ps time-resolved Laue crystallography (2012)
  • Author(s): F. Schotte, H. S. Cho, V. R. I. Kaila, H. Kamikubo, N. Dashdorj, E. R. Henry, T. J. Graber, R. Henning, M. Wulff, G. Hummer, M. Kataoka, P. A. Anfinrud
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 109 Pages: 19256-19261
  • Peer Reviewed
• [Journal Article] Structural basis for Arf6.MKLP1 complexformation on the Flemming bodyresponsible for cytokinesis (2012)
  • Author(s): H. Makyio, M. Ohgi, T. Takei, S. Takahashi, H. Takatsu, Y. Katoh, A. Hanai, T. Ueda, Y. Kanaho, Y. Xie, H.-W. Shin, H. Kamikubo, M. Kataoka, M. Kawasaki, R. Kato, S. Wakatsuki, K. Nakayama
  • Journal Title: EMBO J Volume: 31 Pages: 2590-2603
  • Peer Reviewed
• [Journal Article] 中性子生物物理学の展開 (2012)
  • Author(s): 片岡幹雄
  • Journal Title: 波紋 Volume: 22 Pages: 132-138
  • NAID: 130007516782
• [Journal Article] Watching a signaling protein function in real time via 100-ps time-resolved Laue crystallography (2012)
  • Author(s): Friedrich Schotte
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 109 Pages: 19256-19261
  • Peer Reviewed
• [Journal Article] Maintenance of the secondary structure of horse cytochrome c during the conversion process of monomers to oligomers by addition of ethanol (2012)
  • Author(s): Shun Hirota
  • Journal Title: J. Biochem. Volume: 152 Pages: 521-529
  • Peer Reviewed
• [Journal Article] Time-resolved observation of chiral-index-selective wrapping on single-walled carbon nanotube with non-aromatic polysilane (2012)
  • Author(s): Woojung Chung
  • Journal Title: J. Am. Chem. Soc. Volume: 135 Pages: 2374-2383
  • Peer Reviewed
• [Journal Article] Comprehensive determination of protein tyrosine pKa values for photoactive yellow protein using indirect ^<13>C NMR spectroscopy (2012)
  • Author(s): N.Alia Oktaviani
  • Journal Title: Biophys.J. Volume: 102 Issue: 3 Pages: 579-586
  • DOI: 10.1016/j.bpj.2011.12.024
  • Peer Reviewed
• [Journal Article] Comprehensivedetermination of protein tyrosine pKavalues for photoactive yellow protein usingindirect 13C NMR spectroscopy (2011)
  • Author(s): N. A. Oktaviani, T. J. Pool, H. Kamikubo, J. Slager, R. M. Scheek, M. Kataoka, F. A.A. Mulder
  • Journal Title: Biophys. J Volume: 102 Pages: 579-586
  • Peer Reviewed
• [Journal Article] 生物研究における中性子 (2011)
  • Author(s): 片岡幹雄
  • Journal Title: 波紋 Volume: 21 Pages: 243-246
  • NAID: 130007516830
  • Peer Reviewed
• [Journal Article] Solvent penetration in photoactive yellow protein R52Q mutant: a theoretical study (2011)
  • Author(s): D. J. Sindhikara, N. Yoshida, M. Kataoka, F. Hirata
  • Journal Title: J. Mol. Liq Volume: 164 Pages: 120-122
  • Peer Reviewed
• [Journal Article] Changes in the hydrogen-bondnetwork around the chromophore of photoactive yellow protein in the groundand excited states (2011)
  • Author(s): M. Mizuno, H. Kamikubo, M. Kataoka, Y. Mizutani
  • Journal Title: J. Phys. Chem. B Volume: 115 Pages: 9306-9310
  • Peer Reviewed
• [Journal Article] 中性子非弾性散乱による生体高分子ダイナミックスの研究 (2011)
  • Author(s): 中川洋,片岡幹雄
  • Journal Title: 高分子 Volume: 60 Pages: 195-196
  • NAID: 10027971886
• [Journal Article] Changes in the Hydrogen-Bond Network around the Chromophore of Photoactive Yellow Protein in the Ground and Excited States (2011)
  • Author(s): Misao Mizuno, Hironari Kamikubo, Mikio Kataoka and Yasuhisa Mizutani
  • Journal Title: J. Phys. Chem. B Volume: 115 Issue: 29 Pages: 9306-9310
  • DOI: 10.1021/jp2029399
  • Peer Reviewed
• [Journal Article] Solvent penetration in photoactive yellow protein R52Q mutant : a theoretical study (2011)
  • Author(s): Daniel, J.Sindhikara
  • Journal Title: J.Mol.Liq. Volume: 164 Issue: 1-2 Pages: 120-122
  • DOI: 10.1016/j.molliq.2011.04.007
  • Peer Reviewed
• [Journal Article] 中性子弾性散乱による生体高分子ダイナミックスの研究 (2011)
  • Author(s): 中川洋, 片岡幹雄
  • Journal Title: 高分子 Volume: 60 Pages: 195-196
• [Journal Article] Systematic alanine insertion reveals the essential regions that encode structure formation and activity of dihydrofolate reductase (2011)
  • Author(s): Rumi Shiba
  • Journal Title: BIOPHYSICS Volume: 7 Pages: 1-10
  • NAID: 130000406413
  • Peer Reviewed
• [Journal Article] Systematic alanine insertion reveals the essential regions that encode structure formation and activity of dihydrofolate reductase (2010)
  • Author(s): R. Shiba, M. Umeyama, S. Tsukasa, H. Kamikubo, Y. Yamazaki, M. Yamaguchi, M.Iwakura, M. Kataoka
  • Journal Title: Biophysics Volume: 7 Pages: 1-10
  • NAID: 130000406413
  • Peer Reviewed
• [Journal Article] Percolation of hydration water as a control of protein dynamics (2010)
  • Author(s): H. Nakagawa, M. Kataoka
  • Journal Title: J. Phys. Soc. Jpn Volume: 79 Pages: 83801-83801
  • NAID: 40017245105
  • Peer Reviewed
• [Journal Article] Size-controlled aggregation of cube-shaped EuS nanocrystals with magneto-opticproperties in solution phase (2010)
  • Author(s): A. Tanaka, H. Kamikubo, M. Kataoka, Y. Hasegawa, T. Kawai
  • Journal Title: Langmuir Volume: 27 Pages: 104-108
  • Peer Reviewed
• [Journal Article] Cytochrome c polymerization by successive domain swapping at the C-terminal helix (2010)
  • Author(s): S. Hirota, Y. Hattori, S. Nagao, M.Taketa, H. Komori, H. Kamikubo, Z. Wang, I. Takahashi, S. Negi, Y. Sugiura, M. Kataoka, Y. Higuchi
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 107 Pages: 12854-12859
  • NAID: 120005716875
  • Peer Reviewed
• [Journal Article] フォトアクティブイェロープロテインの中性子結晶構造解析 (2010)
  • Author(s): 上久保裕生,山口繁生,片岡幹雄
  • Journal Title: Radioisotopes Volume: 59 Pages: 289-297
  • NAID: 10026244827
  • Peer Reviewed
• [Journal Article] Percolation of hydration water as a control of protein dynamics. (2010)
  • Author(s): H.Nakagawa, M.Kataoka.
  • Journal Title: J.Phys.Soc.Jpn 79 Pages: 83801-83801
  • NAID: 40017245105
  • Peer Reviewed
• [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease. (2010)
  • Author(s): S.Kato, H.Kamikubo, S.Hirano, Y.Yamazaki, M.Kataoka.
  • Journal Title: Biophys.J. 98 Pages: 678-786
  • Peer Reviewed
• [Journal Article] Effect of conformational states on protein dynamical transition (2010)
  • Author(s): Hiroshi Nakagawa
  • Journal Title: Biochim.Biophys.Acta Volume: 1804 Pages: 27-33
  • Peer Reviewed
• [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease (2010)
  • Author(s): Shingo Kato
  • Journal Title: Biophys.J. Volume: 98 Pages: 678-786
  • Peer Reviewed
• [Journal Article] Self-Assembly and Enhanced Magnetic Properties of Three-dimensional Superlattice Structures Composed of Cube- and Sphere-Shaped EuS Nanocrsytals (2010)
  • Author(s): Atsushi Tanaka
  • Journal Title: Chem.Mat. Volume: 22 Pages: 1776-1781
  • Peer Reviewed
• [Journal Article] Cytochrome c polymerization by successive domain swapping at the C-terminal helix (2010)
  • Author(s): Shun Hirota
  • Journal Title: Proc.Natl.Acad.Sci.USA Volume: 107 Pages: 12854-12859
  • Peer Reviewed
• [Journal Article] Percolation of hydration water as a control of protein dynamics (2010)
  • Author(s): Hiroshi Nakagawa
  • Journal Title: J.Phys.Soc.Jpn Volume: 79 Pages: 83801-83801
  • Peer Reviewed
• [Journal Article] Size-controlled aggregation of cube-shaped EuS nanocrystals with magneto-optic properties in solution (2010)
  • Author(s): Atsushi Tanaka
  • Journal Title: Langmuir Volume: 27 Pages: 104-108
  • Peer Reviewed
• [Journal Article] フォトアクティブイェロープロテインの中性子結晶構造解析 (2010)
  • Author(s): 上久保裕生
  • Journal Title: RADIOISOTOPES Volume: 59 Pages: 289-297
  • NAID: 10026244827
• [Journal Article] Effect of conformational states on protein dynamical transition (2010)
  • Author(s): H.Nakagawa
  • Journal Title: Biochim.Biophys.Acta 1804 Pages: 27-33
  • Peer Reviewed
• [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease (2010)
  • Author(s): Shingo Kato
  • Journal Title: Biophys.J 98 Pages: 678-686
  • Peer Reviewed
• [Journal Article] Self-assembling formation and enhanced magnetic properties of three-dimensional super-lattice structures composed of cube- and sphere-shaped EuS nanocrsytals (2010)
  • Author(s): Atsushi Tanaka
  • Journal Title: Chemistry of Materials (印刷中)
  • Peer Reviewed
• [Journal Article] Effect of conformational states on protein dynamical transition (2009)
  • Author(s): H. Nakagawa, H. Kamikubo, M. Kataoka
  • Journal Title: Biochim. Biophys. Acta Volume: 1804 Pages: 27-33
  • Peer Reviewed
• [Journal Article] Self-assembly and enhanced magnetic properties of three-dimensional superlattice structures composed of cube-shaped EuS nanocrystals (2009)
  • Author(s): A. Tanaka, H. Kamikubo, Y. Doi, Y. Hinatsu, M. Kataoka, T. Kawai, Y. Hasegawa
  • Journal Title: Chem. Mater Volume: 22 Pages: 1776-1781
  • Peer Reviewed
• [Journal Article] Nonlocal interactions are responsible for tertiary structure formation in staphylococcalnuclease (2009)
  • Author(s): S. Kato, H. Kamikubo, S. Hirano, Y.Yamazaki, M. Kataoka
  • Journal Title: Biophys. J Volume: 98
  • Peer Reviewed
• [Journal Article] Self-aggregation of magnetic semiconductor EuS nanocrystals (2009)
  • Author(s): Tanaka, Y. Hasegawa, H. Kamikubo, M. Kataoka, T. Kawai
  • Journal Title: Thin Solid Films Volume: 518 Pages: 870-872
  • Peer Reviewed
• [Journal Article] Structural effects on the ultrafast photoisomerization of photoactive yellowprotein. Transient absorption spectroscopy of two point mutants (2009)
  • Author(s): P. Changenet-Barret, P. Plaza, M. M. Martin, H. Chosrowjan, S. Taniguchi, N. Mataga, Y. Imamoto, M. Kataoka
  • Journal Title: J. Phys. Chem. C Volume: 113 Pages: 11605-11613
  • Peer Reviewed
• [Journal Article] 非干渉性中性子非弾性散乱で観るタンパク質ダイナミクスの水和効果 (2009)
  • Author(s): 中川洋,片岡幹雄
  • Journal Title: 波紋 Volume: 19 Pages: 91-94
  • NAID: 130006701975
  • Peer Reviewed
• [Journal Article] Low barrier hydrogen bond in photoactive yellow protein. (2009)
  • Author(s): S.Yamaguchi, H.Kamikubo, K.Kurihara, R.Kuroki, N.Niimura, N.Shimizu, Y.Yamazaki, M.Kataoka.
  • Journal Title: Proc.Natl.Acad.Sci.USA. 106 Pages: 440-444
  • Peer Reviewed
• [Journal Article] Structural effects on the ultrafast photoisomerization of photoactive yellow protein : Transient absorption spectroscopy of two point mutants (2009)
  • Author(s): Pascale Changenet-Barret
  • Journal Title: J.Phys.Chem.C. 113 Pages: 11605-11613
  • Peer Reviewed
• [Journal Article] Self-aggregation of magnetic semiconductor EuS nanocrystals (2009)
  • Author(s): Atsushi Tanaka
  • Journal Title: Thin Solid Films 518 Pages: 870-872
  • Peer Reviewed
• [Journal Article] Low barrier hydrogen bond in photoactive yellow protein (2009)
  • Author(s): Shigeo Yamaguchi
  • Journal Title: Proceedings of the National Academy of Science of USA 106 Pages: 440-444
  • Peer Reviewed
• [Journal Article] Nucleotide-dependentconformational changes and assembly of the AAA ATPase SKD1/VPS4B (2008)
  • Author(s): M. Inoue, H. Kamikubo, M. Kataoka,Ryuichi Kato, T. Yoshimori, S. Wakatsuki, M. Kawasaki
  • Journal Title: Traffic Volume: 9 Pages: 2180-2189
  • Peer Reviewed
• [Journal Article] Low-barrier hydrogen bond in photoactiveyellow protein (2008)
  • Author(s): S. Yamaguchi, H. Kamikubo, K. Kurihara, R. Kuroki, N. Niimura, N. Shimizu, Y. Yamazaki, M. Kataoka
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 106 Pages: 440-444
  • Peer Reviewed
• [Journal Article] Diverse Roles of Glycine Residues Conserved in Photoactive Yellow Proteins (2008)
  • Author(s): Yasushi Imamoto
  • Journal Title: Biophysical Journal 94 Pages: 3620-3628
  • Peer Reviewed
• [Journal Article] Role of the N-terminal region in the function of the photosynthetic bacterium transcription regulator PpsR (2008)
  • Author(s): Yoichi Yamazaki
  • Journal Title: Photochemistry and Photobiology 84 Pages: 839-844
  • Peer Reviewed
• [Journal Article] Mechanism of induced folding : Both folding before binding andbinding before folding can be realized in staphylococcal nuclease mutants (2008)
  • Author(s): Masayoshi, Onitsuka
  • Journal Title: Proteins : Structures, Functions and Bioinformatics 72 Pages: 837-847
  • Peer Reviewed
• [Journal Article] Hydration effects on low-frequency protein dynamics observed in simulated neutron scattering spectra (2008)
  • Author(s): Yasumasa Joti
  • Journal Title: Biophysical Journal 94 Pages: 4435-4443
  • Peer Reviewed
• [Journal Article] The photoreaction of the photoactive yellow protein domain in the light sensor histidine kinase Par is influenced by the C-terminal domains (2008)
  • Author(s): Hironari Kamikubo
  • Journal Title: Photochemistry and Photobiology 84 Pages: 895-902
  • Peer Reviewed
• [Journal Article] Low-temperature spectroscopy of Met100Ala mutant of photoactive yellow protein (2008)
  • Author(s): Yasushi Imamoto
  • Journal Title: Photochemistry and Photobiology 84 Pages: 970-976
  • Peer Reviewed
• [Journal Article] Interaction between N-terminal loop and β-scaffold of photoactive yellow protein (2008)
  • Author(s): Miki Harigai
  • Journal Title: Photochemistry and Photobiology 84 Pages: 1031-1037
  • Peer Reviewed
• [Journal Article] Hydration affects both harmonic and anharmonic nature of protein dynamics (2008)
  • Author(s): Hiroshi Nakagawa
  • Journal Title: Biophysical Journal 95 Pages: 2916-2923
  • Peer Reviewed
• [Journal Article] Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B (2008)
  • Author(s): Michio Inoue
  • Journal Title: Traffic 9 Pages: 2180-2189
  • Peer Reviewed
• [Presentation] イェロープロテインの光反応中の構造変化を見る (2013)
  • Author(s): 片岡幹雄
  • Organizer: 日本物理学会第68回年次大会
  • Place of Presentation: 広島県東広島市
  • Year and Date: 2013-03-26
• [Presentation] Is tertiary structure really required for specific function of a protein? (2013)
  • Author(s): 片岡幹雄
  • Organizer: American Physical Society (APS) March Meeting 2013
  • Place of Presentation: Baltimore, USA
  • Year and Date: 2013-03-22
  • Invited
• [Presentation] Is the protein tertiary structure necessary for a specific function? (2013)
  • Author(s): 片岡幹雄
  • Organizer: International Symposium on Protein Folding and its Biological Significance
  • Place of Presentation: 愛知県岡崎市
  • Year and Date: 2013-03-14
  • Invited
• [Presentation] Structure and photoreaction of photoactive yellow protein (2013)
  • Author(s): 片岡幹雄
  • Organizer: The 4th Japan-France Joint Symposium “Imaging of spatiotemporal hierarchies in living cells -An overview of dynamics from molecules to cells-“
  • Place of Presentation: 兵庫県佐用郡
  • Year and Date: 2013-01-10
  • Invited
• [Presentation] Is the protein tertiary structure necessary for a specificfunction? (2013)
  • Author(s): M. Kataoka
  • Organizer: American Physical Society (APS)March Meeting 2013
  • Place of Presentation: Baltimore, MD, USA
• [Presentation] Structure, dynamics and function of staphylococcal nuclease (2012)
  • Author(s): 片岡幹雄
  • Organizer: The 6th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 京都府京都市
  • Year and Date: 2012-12-06
  • Invited
• [Presentation] Effect of hydration on protein dynamics (2012)
  • Author(s): 片岡幹雄
  • Organizer: The 6th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 京都府京都市
  • Year and Date: 2012-12-05
• [Presentation] Protein dynamics and hydration water (2012)
  • Author(s): 片岡幹雄
  • Organizer: 10th International Conference on Quasielastic Neutron Scattering
  • Place of Presentation: 栃木県日光市
  • Year and Date: 2012-10-04
  • Invited
• [Presentation] 水和がタンパク質動力学に与える影響 (2012)
  • Author(s): 片岡幹雄
  • Organizer: 新学術領域研究合同公開シンポジウム「ゆらぎと水－生命のエネルギーと機能の分子機構を探る」
  • Place of Presentation: 大阪府大阪市
  • Year and Date: 2012-09-14
• [Presentation] Molecular Anatomy of Staphylococcal Nuclease (2012)
  • Author(s): Mikio Kataoka
  • Organizer: 4th Japan-Korea Seminar on Biomolecular Sciences : Experiments and Simulations
  • Place of Presentation: 奈良市(招待講演)
  • Year and Date: 2012-01-09
• [Presentation] Incorporation of Fluorescent Non-natural Amino Acids into Staphylococcal Nuclease for FRET Analyses of Induced Folding (2012)
  • Author(s): Mikio Kataoka
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-08
• [Presentation] Study on the Denatured Structure of Staphylococcal Nuclease by Using Tryptophan Triplet State Quenching (2012)
  • Author(s): Mariko Yamaguchi
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-08
• [Presentation] Comparison of Structural Elements between Staphylococcal Nuclease and the C-terminal Domain of Human p100 (2012)
  • Author(s): Sho Ueyanagi
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-08
• [Presentation] Attempt of Functional Modification of a Protein by Element Implantation (2012)
  • Author(s): Eri Sakai
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-08
• [Presentation] Denatured Structure of Staphylococcal Nuclease Studied by Quenching of Tryptophan Triplet State by Cysteine (2012)
  • Author(s): Toshihiro Okada
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-08
• [Presentation] The Roles of the Low Barrier Hydrogen Bond Involved in the Light Sensor Protein, Photoactive Yellow Protein (2012)
  • Author(s): Hironari Kamikubo
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-07
• [Presentation] Refinement of Function Element of Dihydrofolate Reductase by the Systematic Alanine Insertion (2012)
  • Author(s): Rumi Shiba
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-07
• [Presentation] The Role of N-terminal Region for Photoreaction of Various Photoactive Yellow Proteins (2012)
  • Author(s): Ryota Odani
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-07
• [Presentation] Geometric Restriction Facilitates LBHB Formation in Photoactive Yellow Protein (2012)
  • Author(s): Yusuke Nishiguchi
  • Organizer: The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
  • Place of Presentation: 奈良市
  • Year and Date: 2012-01-07
• [Presentation] Protein dynamics and hydration water (2012)
  • Author(s): M. Kataoka
  • Organizer: The 10th International Conference on Quasi Elastic Neutron Scattering
  • Place of Presentation: Nikko
• [Presentation] The formation and role of low barrier hydrogen bond in photoactive yellow protein (2011)
  • Author(s): Mikio Kataoka
  • Organizer: 物構研シンポジウム'11量子ビーム化学の展望
  • Place of Presentation: つくば市(招待講演)
  • Year and Date: 2011-12-07
• [Presentation] Physicochemical properties of low barrier hydrogen bonds involved in Photoactive Yellow Protein (2011)
  • Author(s): Hironari Kamikubo
  • Organizer: 1st Asia-Oceania Conference on Neutron Scattering
  • Place of Presentation: つくば市(招待講演)
  • Year and Date: 2011-11-24
• [Presentation] The roles of the low barrier hydrogen bond involved in Photoactive Yellow Protein (2011)
  • Author(s): Hironari Kamikubo
  • Organizer: 17th International Biophysics Congress (IUPAB)
  • Place of Presentation: Beijing, China
  • Year and Date: 2011-11-02
• [Presentation] Refinement of function element of dihydrofolate reductase by the systematic alanine insertion (2011)
  • Author(s): Rumi Shiba
  • Organizer: 17th International Biophysics Congress (IUPAB)
  • Place of Presentation: Beijing, China
  • Year and Date: 2011-10-31
• [Presentation] Local structural change of staphylococcal nuclease wild type and its non-native mutant with guanidine hydrochloride monitored by tryptophan triplet quenching (2011)
  • Author(s): Mariko Yamaguchi
  • Organizer: 17th International Biophysics Congress (IUPAB)
  • Place of Presentation: Beijing, China
  • Year and Date: 2011-10-31
• [Presentation] Comparison of structural elements between Staphylococcal nuclease and the C-terminal domain of Human p100 (2011)
  • Author(s): Sho Ueyanagi
  • Organizer: 17th International Biophysics Congress (IUPAB)
  • Place of Presentation: Beijing, China
  • Year and Date: 2011-10-31
• [Presentation] タンパク質動力学と水和 (2011)
  • Author(s): 片岡幹雄
  • Organizer: 日本分光学会テラヘルツ分光部会シンポジウム「テラヘルツ分光法の最先端V」～バイオテラヘルツ分光～
  • Place of Presentation: 横浜市(招待講演)
  • Year and Date: 2011-09-28
• [Presentation] Solution structure of the complex states of Rhodobacter capsulatus PYP with its binding protein (2011)
  • Author(s): Yoichi Yamazaki
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-18
• [Presentation] Analysis of low barrier hydrogen bond in Photoactive Yellow Protein, Geometric restriction facilitates LBHB formation in PYP (2011)
  • Author(s): Yusuke Nishiguchi
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-18
• [Presentation] The Role of N-terminal Region for Photoreaction of Various Photoactive Yellow Proteins (2011)
  • Author(s): Ryota Odani
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-18
• [Presentation] Development of light dependent protein activity control system by use of interaction of the Rc-PYP (2011)
  • Author(s): Shinya Setoguchi
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-18
• [Presentation] Structural Analysis of Intrinsically Disordered Protein Model using FRET (2011)
  • Author(s): Takuya Muto
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-18
• [Presentation] Attempt of functional modification of a protein by element implantation (2011)
  • Author(s): Eri Sakai
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-18
• [Presentation] Denatured Structure of Staphylococcal Nuclease Studied by Triplet State Quenching of Tryptophan by Cysteine (2011)
  • Author(s): Toshihiro Okada
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-17
• [Presentation] Cytochrome c polymerization by domain swapping (2011)
  • Author(s): Satoshi Nagao
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-17
• [Presentation] Difference in local structure between staphylococcal nuclease wild type and its non-native mutant studied by tryptophan triplet quenching (2011)
  • Author(s): Mariko Yamaguchi
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-16
• [Presentation] Classification of function element of dihydrofolate reductase by the systematic alanine insertion (2011)
  • Author(s): Rumi Shiba
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-16
• [Presentation] Comparison of structural elements between Staphylococcal nuclease and the C-terminal domain of Human p100 (2011)
  • Author(s): Sho Ueyanagi
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 姫路市
  • Year and Date: 2011-09-16
• [Presentation] Is tertiary structure required for a specific function? (2011)
  • Author(s): Mikio Kataoka
  • Organizer: Telluride Conference on Protein Dynamics 2011
  • Place of Presentation: Telluride, USA(招待講演)
  • Year and Date: 2011-08-04
• [Presentation] High resolution neutron crystallography of photoactive yellow protein-Discovery of low barrier hydrogen bond (2011)
  • Author(s): Mikio Kataoka
  • Organizer: 第3回韓日生体分子科学セミナー
  • Place of Presentation: Cheju-do, Korea(招待講演)
  • Year and Date: 2011-02-27
• [Presentation] High resolution neutron crystal structure of photoactive yellow protein : Discovery of low barrier hydrogen bond (2011)
  • Author(s): Mikio Kataoka
  • Organizer: The 7th Asian Biophysics Association (ABA) Symposium
  • Place of Presentation: New Delhi, India(招待講演)
  • Year and Date: 2011-02-02
• [Presentation] Is tertiary structure required for a specific function? (2011)
  • Author(s): M. Kataoka
  • Organizer: Telluride Science Research Center (TSRC) Workshopon Protein Dynamics 2011
  • Place of Presentation: Telluride, CO,USA
• [Presentation] High resolution neutron crystal structure of photoactive yellow protein: Discovery of low barrierhydrogen bond (2011)
  • Author(s): M. Kataoka
  • Organizer: The 7th Asian BiophysicsAssociation (ABA) Symposium
  • Place of Presentation: New Delhi,India
• [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction (2010)
  • Author(s): Mikio Kataoka
  • Organizer: International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
  • Place of Presentation: Honolulu, U.S.A.(招待講演)
  • Year and Date: 2010-12-19
• [Presentation] Fluctuation controls enzymatic activity of Staphylococcal nuclease (2010)
  • Author(s): Hironari Kamikubo
  • Organizer: The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
  • Place of Presentation: 大津市
  • Year and Date: 2010-12-01
• [Presentation] Classification of the functional element of dihydrofolate reductase by the systematic alanine insertion (2010)
  • Author(s): Rumi Shiba
  • Organizer: The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
  • Place of Presentation: 大津市
  • Year and Date: 2010-12-01
• [Presentation] FRET analysis of structural changes in staphylococcal nuclease (2010)
  • Author(s): Yusuke Kishi
  • Organizer: The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
  • Place of Presentation: 大津市
  • Year and Date: 2010-12-01
• [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix (2010)
  • Author(s): Zhonghua Wang
  • Organizer: The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
  • Place of Presentation: 大津市
  • Year and Date: 2010-12-01
• [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease (2010)
  • Author(s): Hiroki Sawada
  • Organizer: The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
  • Place of Presentation: 大津市
  • Year and Date: 2010-11-30
• [Presentation] Measurements of loop formation in the denatured state of staphylococcal nuclease (2010)
  • Author(s): Mariko Yamaguchi
  • Organizer: The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
  • Place of Presentation: 大津市
  • Year and Date: 2010-11-30
• [Presentation] 中性子非弾性散乱と分子動力学によるタンパク質の揺らぎと水和水ダイナミクスの研究 (2010)
  • Author(s): 中川洋
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪市
  • Year and Date: 2010-09-24
• [Presentation] 蛋白質機能の発現に構造は必須か? (2010)
  • Author(s): 片岡幹雄
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪市
  • Year and Date: 2010-09-23
• [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix (2010)
  • Author(s): Shun Hirota
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-22
• [Presentation] A case of EspB from enterohaemorrhagic Escherichia coli (2010)
  • Author(s): Daizo Hamada
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-22
• [Presentation] Property of a structural element of SNase-like domain in human p100 (2010)
  • Author(s): Yoko Ogawa
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-22
• [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease (2010)
  • Author(s): Hiroki Sawada
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-22
• [Presentation] FRET analysis of structural changes in Staphylococcal nuclease (2010)
  • Author(s): Yusuke Kishi
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-22
• [Presentation] The mechanism of induced folding of Staphylococcal nuclease : Folding before binding or binding before folding? (2010)
  • Author(s): Mikio Kataoka
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市(招待講演)
  • Year and Date: 2010-09-21
• [Presentation] Effects of trehalose on the structures and dynamics of lipid membrane (2010)
  • Author(s): Tomomi Masui
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-21
• [Presentation] Solution structure of the light sensor histidine kinase of Ppr comprised of the PYP and Bph domains (2010)
  • Author(s): Junko Miura
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-21
• [Presentation] Solution structural analysis of Drosophila GGA (2010)
  • Author(s): Maiko Naruse
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-21
• [Presentation] Analysis of solution state of the interaction protein of Rc-PYP (2010)
  • Author(s): Miki Hayashi
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-21
• [Presentation] The role of each residue in the fiexible Ω loop of Staphylococcal nuclease on the catalytic activity (2010)
  • Author(s): Changjun Ahn
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-21
• [Presentation] Classification of the functional element of dihydrofolate reductase (DHFR) by the systemic alanine insertion (2010)
  • Author(s): Rumi Shiba
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-21
• [Presentation] Synthesis of an artificial enzyme by implanting the functional elements of SNase (2010)
  • Author(s): Hironari Kamikubo
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-21
• [Presentation] Urea denaturation of staphylococcal nuclease monitored by tryptophan-cysteine distance (2010)
  • Author(s): Mariko Yamaguchi
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-20
• [Presentation] Substitution effects of basic residues in the photoactive yellow protein of Rhodobacter caplsulatus (2010)
  • Author(s): Yoichi Yamazaki
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-09-20
• [Presentation] Photoactive Yellow Proteinにおける発色団の機能変調 (2010)
  • Author(s): 山崎洋一
  • Organizer: 第16回日本光生物学協会年会
  • Place of Presentation: 大阪市
  • Year and Date: 2010-08-11
• [Presentation] Effect of hydration water on protein dynamics (2010)
  • Author(s): Mikio Kataoka
  • Organizer: The 4th Shanghai International Conference on Biophysics and Molecular Biology
  • Place of Presentation: Shanghai-Jiashan, China(招待講演)
  • Year and Date: 2010-08-10
• [Presentation] The effect of alanine insertion mutation for folding process (2010)
  • Author(s): Hiroki Sawada
  • Organizer: The 4th Shanghai International Conference on Biophysics and Molecular Biology
  • Place of Presentation: Shanghai-Jiashan, China
  • Year and Date: 2010-08-09
• [Presentation] Extraction of the regions encoded foldability and/or functionability from dihydrofolate reductase by the systematic alanine insertion (2010)
  • Author(s): Rumi Shiba
  • Organizer: The 4th Shanghai International Conference on Biophysics and Molecular Biology
  • Place of Presentation: Shanghai-Jiashan, China
  • Year and Date: 2010-08-09
• [Presentation] 精子由来蛋白質IZUMO,その構造と受精膜融合での役割 (2010)
  • Author(s): 萩原義久
  • Organizer: 第10回日本蛋白質科学会年会
  • Place of Presentation: 札幌市
  • Year and Date: 2010-06-18
• [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出 (2010)
  • Author(s): 芝るみ
  • Organizer: 第10回日本蛋白質科学会年会
  • Place of Presentation: 札幌市
  • Year and Date: 2010-06-16
• [Presentation] Effect of hydration on protein dynamics (2010)
  • Author(s): Mikio Kataoka
  • Organizer: Leopoldina-Symposium on the Complexity Connecting Biomolecular Structure and Solvation Dynamics
  • Place of Presentation: Bochum, Germany(招待講演)
  • Year and Date: 2010-05-26
• [Presentation] Low barrier hydrogenbond in photoactive yellow protein and itsrole in photoreaction (2010)
  • Author(s): M. Kataoka
  • Organizer: International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
  • Place of Presentation: Honolulu, U. S. A.
• [Presentation] Effect of hydration water on protein dynamics (2010)
  • Author(s): M. Kataoka
  • Organizer: The 4th Shangai International Conference on Biophysics and Molecular Biology(2010SICBM)
  • Place of Presentation: Shanghai-Jiashan, China
• [Presentation] Effect of hydration on protein dynamics (2010)
  • Author(s): M. Kataoka
  • Organizer: Leopoldina-Symposium on the ComplexityConnecting Biomolecular Structure and Solvation Dynamics
  • Place of Presentation: Bochum, Germany
• [Presentation] Effect of hydration on protein dynamics. (2010)
  • Author(s): M.Kataoka.
  • Organizer: Leopoldina-Symposium on the Complexity Connecting Biomolecular Structure and Solvation Dynamics.
  • Place of Presentation: Bochum, Germany
• [Presentation] Structure and photoreaction of photoactive yellow protein : Direct observation of low barrier hydrogen bond and its roles (2009)
  • Author(s): Mikio Kataoka
  • Organizer: ATI International Forum 2009, "Protein Structure Determination and Applications"
  • Place of Presentation: 東海
  • Year and Date: 2009-03-09
• [Presentation] Mechanism of Induced Folding of Staphylococcal Nuclease : Implication to Natively Unfolding Protein (2009)
  • Author(s): Mikio Kataoka
  • Organizer: The 6th Asian Biophysics Association (ABA) Symposium
  • Place of Presentation: 香港(中国)
  • Year and Date: 2009-01-12
• [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction (2009)
  • Author(s): M. Kataoka
  • Organizer: Telluride Science Research Center (TSRC) Workshop on Protein Dynamics 2009
  • Place of Presentation: Telluride, CO, USA
• [Presentation] タンパク質動力学に対する水和の効果 (2009)
  • Author(s): 片岡幹雄
  • Organizer: 第9回日本蛋白質科学会年会
  • Place of Presentation: 熊本
• [Presentation] イェロープロテインの低障壁水素結合の形成とその役割 (2009)
  • Author(s): 片岡幹雄
  • Organizer: 第36回生体分子化学討論会
  • Place of Presentation: 札幌
• [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction (2009)
  • Author(s): Mikio Kataoka
  • Organizer: Telluride Science Research Center (TSRC) Work shop on Protein Dynamics 2009
  • Place of Presentation: テルライド(アメリカ)
• [Presentation] Effect of Hydration Water on Protein Dynamics (2009)
  • Author(s): Mikio Kataoka
  • Organizer: The 3rd UT Horiba International Symposium on Hydrogen and water in condensed matter physics
  • Place of Presentation: 千葉
• [Presentation] Photoactive Yellow Proteinの低障壁水素結合 (2009)
  • Author(s): 山口繁生
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] 中性子非弾性散乱で蛋白質の熱揺らぎを測る (2009)
  • Author(s): 片岡幹雄
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] Rc-PYPと相互作用タンパク質を用いた酵素活性の光制御系の作製 (2009)
  • Author(s): 久保晴政
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] Rhodobacter capsulatus由来PYPの相互作用様式の解析 (2009)
  • Author(s): 山崎洋一
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] Rc-PYPの低温分光 (2009)
  • Author(s): 濱口祐也
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] キメラを用いたPhotoactive Yellow Proteinの研究 (2009)
  • Author(s): 松本啓佑
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] Staphylococcal nucleaseアラニン挿入変異体の結晶学的研究 (2009)
  • Author(s): 吉岡紘志
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] エレメント置換による蛋白質の機能獲得の試み (2009)
  • Author(s): 小賀坂彰浩
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] アゾベンゼンを用いた構造エレメントのモジュレーション (2009)
  • Author(s): 齊藤謙介
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] 誘導折り畳み反応のΦ値解析:スタフィロコッカルヌクレアーゼ変異体の誘導折り畳み反応におけるリガンド結合の役割 (2009)
  • Author(s): 鬼塚正義
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] 電子常磁性共鳴分光法による天然変性Staphylococcal nuclease変異体の構造解析 (2009)
  • Author(s): 澤田宏起
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現および構造形成領域の抽出 (2009)
  • Author(s): 芝るみ
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] 網羅的アラニン挿入変異解析によるHuman p100 SNase様ドメインの構造形成に関わる領域の抽出 (2009)
  • Author(s): 小川洋子
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] 蛋白質の調和運動と非調和運動に対する水和効果 (2009)
  • Author(s): 中川洋
  • Organizer: 第47回日本生物物理学会年会
  • Place of Presentation: 徳島
• [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction (2009)
  • Author(s): Mikio Kataoka
  • Organizer: The 1st NCTU-NAIST workshop on "Molecular/Nano Science"
  • Place of Presentation: 新竹(台湾)
• [Presentation] 中性子結晶構造解析による蛋白質中の「低障壁」水素結合の発見 (2009)
  • Author(s): 上久保裕生
  • Organizer: 第9回日本中性子科学会年会
  • Place of Presentation: 茨城
• [Presentation] 蛋白質動力学転移における水和水の構造とダイナミクス (2008)
  • Author(s): 中川洋
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-05
• [Presentation] 光受容タンパク質AppAの分子内相互作用機構 (2008)
  • Author(s): 中西勇人
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-05
• [Presentation] Human p100のSNase様ドメインの折れ畳み能 (2008)
  • Author(s): 米田知可子
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-04
• [Presentation] 網羅的アラニン挿入変異解析法によるジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出 (2008)
  • Author(s): 芝るみ
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-04
• [Presentation] 拡散係数変化によるPYPの光反応における構造変化の起源の検討 (2008)
  • Author(s): Javaid Shahbaz Khan
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-04
• [Presentation] Photoactive yellow proteinの構造および機能エレメントの同定 (2008)
  • Author(s): 山田好輝
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-04
• [Presentation] 核酸分解酵素におけるループの揺らぎと機能の関係 (2008)
  • Author(s): 田所成文
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] L1M08が担うStaphylgcoccal Nucleaseの折り畳寿における役割の解明 (2008)
  • Author(s): 中垣礼寧
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] アラニン挿入変異がキネティクスに与える影響 (2008)
  • Author(s): 澤田宏起
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] Rhodobacter capsulatus由来PYPの複合体状態における分光学的特長 (2008)
  • Author(s): 山崎洋一
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] 光センサー型ヒスチジンキナーゼPYPドメインの光反応に対するC末端ドメインの影響 (2008)
  • Author(s): 上久保裕生
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] Rc-PYPにおけるN末端部位の役割 (2008)
  • Author(s): 太田成人
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] Photoactive Yellow Protein中の2種のshort hydrogen bondの直接観察 (2008)
  • Author(s): 山口繁生
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] Effect of hydration water on protein dynamics (2008)
  • Author(s): Mikio Kataoka
  • Organizer: 150th Anniversary of Japan-France Relation-ship Workshop on Water & Cell Physiology
  • Place of Presentation: 京都
  • Year and Date: 2008-11-26
• [Presentation] Effect of hydration on the glass-like transition of protein (2008)
  • Author(s): Mikio Kataoka
  • Organizer: Japan-France Bilateral Joint Seminar 2008 "Fron tiers of Glassy Physics"
  • Place of Presentation: 京都
  • Year and Date: 2008-11-19
• [Presentation] Protein Dynamics and Structure Studied by Neutron Scattering (2008)
  • Author(s): Mikio Kataoka
  • Organizer: Asia Science Seminar on "Frontier Science at High-Intensity Proton Accelerators"
  • Place of Presentation: 北京(中国)
  • Year and Date: 2008-10-21
• [Presentation] Effect of hydration and conformational state on protein dynamics (2008)
  • Author(s): Maio Kataoka
  • Organizer: Workshop Biomolecular Dynamics and Protein-Water Interactions
  • Place of Presentation: ミュンヘン(ドイツ)
  • Year and Date: 2008-09-25
• [Presentation] Staphylococcal nucleaseの誘導折り畳み機構 (2008)
  • Author(s): 片岡幹雄
  • Organizer: 第8回日本蛋白質科学会年会
  • Place of Presentation: 東京
  • Year and Date: 2008-06-10
• [Book] 生体分子の動きを探る－揺らぎと生体機能－ (2013)
  • Author(s): 片岡幹雄
  • Publisher: 化学同人
• [Book] ひかりエネルギー革命-グリーンフォトニクス-(NAISTグリーンフォトニクス研究チーム編著) (2012)
  • Author(s): 片岡幹雄
  • Publisher: 化学同人,京都
• [Book] ひかりエネルギー革命－グリーンフォトニクス－ (2012)
  • Author(s): 片岡幹雄
  • Total Pages: 121
  • Publisher: 化学同人
• [Book] Neutrons in Soft Matter (Eds.T. Imae, T. Kanaya, M.Furusaka, N. Torikai) (2011)
  • Author(s): M. Kataoka, H. Nakagawa
  • Publisher: John Wiley, NewJersey
• [Book] Water, The Forgotten Biological Molecule(eds.by Denis Le Bihan and Hidenao Fukuyama) (2011)
  • Author(s): M.Kataoka, H.Nakagawa.
  • Publisher: Pan Stanford Publishing (Singapore)
• [Book] Water, The Forgotten Biological Molecule (2011)
  • Author(s): Mikio Kataoka
  • Publisher: Pan Stanford Publishing
• [Book] 揺らぎと生体機能(MedicalBio 10月別冊) (2011)
  • Author(s): 片岡幹雄
  • Publisher: オーム社
• [Book] 光ナノ科学への招待 (2011)
  • Author(s): 片岡幹雄
  • Publisher: 化学同人
• [Book] Neutrons in Soft Matter (2011)
  • Author(s): Mikio Kataoka
  • Publisher: John Wiley
• [Book] 揺らぎと生体機能 (MedicalBio 10月別冊)(寺嶋正秀監修) (2010)
  • Author(s): 片岡幹雄
  • Publisher: オーム社,東京
• [Book] 光ナノ科学への招待(長谷川靖哉、細川陽一郎、中嶋琢也編) (2010)
  • Author(s): 片岡幹雄
  • Publisher: 化学同人,京都
• [Book] Water, The Forgotten Biological Molecule (Eds. D. LeBihan, H. Fukuyama) (2010)
  • Author(s): M. Kataoka, H. Nakagawa
  • Publisher: Pan Stanford Publishing, Singapore
• [Book] Protein dynamics studied by neutron incoherent scattering (2010)
  • Author(s): Mikio Kataoka
  • Publisher: John Wiley(in press)
• [Book] Water andBiomolecules (Eds. K. Kuwajima, Y. Goto, F.Hirata, M. Kataoka, M. Terazima) (2009)
  • Author(s): M. Kataoka, H. Kamikubo
  • Publisher: Springer-Verlag, Berlin
• [Book] 光科学研究の最前線 2(「光科学研究の最前線 2」編集委員会編 (2009)
  • Author(s): 片岡幹雄
  • Total Pages: 208
  • Publisher: 強光子場科学研究懇談会,東京
• [Remarks] (1)光センサータンパク質の構造変化を世界最高レベルの分解能で可視化することに成功(MSN産経ニュース「ベテラン記者のデイリーコラム・坂口至徳の科学の現場を歩く」2012年11月6日、日刊工業新聞 2012年11月7日、日経新聞 2012年11月27日)
• [Remarks] (2)日本中性科学会第 9回学会賞を受賞(科学新聞 2011年11月18日)
• [Remarks] (3) M. Terazima, M. Kataoka and R. Ueoka, "Molecular Science of Fluctuations toward Biological Functions",(Science, 333, 1329. 2011年9月2日)
• [Remarks] (4)タンパク質動力学に対する水和水の役割を解明(科学新聞 2010年8月6日、日経産業新聞 2010年8月16日、日刊工業新聞 2010年8月23日)
• [Remarks] (5)世界で初めてタンパク質に低障壁水素結合を発見(時事通信 2008年12月30日、産経新聞2008年12月31日、奈良日日新聞2009年1月5日、日刊工業新聞2009年1月6日、フジサンケイビジネスアイ2009年1月6日、科学新聞 2009年1月16日)