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Development of model systems for intrinsically disordered protein and understanding of the role of fluctuation on molecular recognition and folding

Planned Research

Project AreaMolecular Science of Fluctuations toward Biological Functions
Project/Area Number 20107006
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionNara Institute of Science and Technology

Principal Investigator

KATAOKA Mikio  奈良先端科学技術大学院大学, 物質創成科学研究科, 教授 (30150254)

Co-Investigator(Renkei-kenkyūsha) KAMIKUBO Hironari  奈良先端科学技術大学院大学, 物質創成科学研究科, 准教授 (20311128)
YAMAZAKI Yoichi  奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (40332770)
YAMAGUCHI Mariko  奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (50521738)
SHIBA Rumi  奈良先端科学技術大学院大学, 物質創成科学研究科, 博士研究員 (70617133)
ENDO Hitoshi  日本原子力研究開発機構, 量子ビーム応用研究部門, 研究員 (40447313)
Project Period (FY) 2008 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥126,620,000 (Direct Cost: ¥97,400,000、Indirect Cost: ¥29,220,000)
Fiscal Year 2012: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2011: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2010: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2009: ¥22,360,000 (Direct Cost: ¥17,200,000、Indirect Cost: ¥5,160,000)
Fiscal Year 2008: ¥35,750,000 (Direct Cost: ¥27,500,000、Indirect Cost: ¥8,250,000)
Keywords天然変性蛋白質 / 誘導折り畳み / 分子認識 / 変性構造 / 結晶構造解析 / Staphylococcal nuclease / 天然変性タンパク質 / FRET / X線結晶構造解析 / 核酸分解酵素 / 揺らぎ / トリプトファン三重項 / 中性子散乱 / ストップトフローCD / 黄色ブドウ球菌核酸分解酵素 / 中性子非弾性散乱 / 水和水 / 標的結合 / タンパク質動力学
Research Abstract

We created various mutants of functional proteins which do not take stable native conformations but possess enzymatic activity as well as the mutants which take native structure without enzymatic activity. The ligand-induced folding of the former mutants and the crystal structure analysis of the latter mutants brought the conclusion that fluctuations or structure dynamics facilitate the ligand recognition and that fluctuations controls the catalytic activity. We also revealed that the hydration water network via hydrogen bond encircled the protein whole molecule is essential for the control of fluctuations.

Report

(7 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (202 results)

All 2013 2012 2011 2010 2009 2008 Other

All Journal Article (63 results) (of which Peer Reviewed: 57 results) Presentation (119 results) (of which Invited: 5 results) Book (15 results) Remarks (5 results)

  • [Journal Article] Preferential domain orientation of HMGB2 determined by the weak intramolecular interactions mediated by the interdomain linker2013

    • Author(s)
      J. Uewaki, H. Kamikubo, J. Kurita, N. Hiroguchi, H. Moriuchi, M. Yoshida, M. Kataoka, N. U.-Tate, S. Tate
    • Journal Title

      Chem.Phys

      Volume: 419 Pages: 212

    • DOI

      10.1016/j.chemphys.2013.02.004

    • URL

      https://pure.teikyo.jp/en/publications/d5a2b53c-f986-4ac3-b994-d5a09681cf5f

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fingerprint signatures of lanthanide circularly polarized luminescence from proteins covalently labeled by a β -diketonate europium(III) chelate2013

    • Author(s)
      J.Yuasa, T. Ohno, H. Tsumatori, R. Shiba, H. Kamikubo, M. Kataoka, Y. Hasegawa, T. Kawai
    • Journal Title

      Chem. Commn

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 働いているタンパク質の構造を実時間で見た!-次世代構造生物科学への期待2013

    • Author(s)
      上久保裕生,片岡幹雄
    • Journal Title

      化学

      Volume: 68 Pages: 74-75

    • Related Report
      2012 Final Research Report
  • [Journal Article] 働いているタンパク質の構造を実時間で見た!-次世代構造生物科学への期待2013

    • Author(s)
      上久保裕生
    • Journal Title

      化学

      Volume: 68 Pages: 74-75

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 1H, 13C, and 15N resonance assignment of photoactive yellow protein2013

    • Author(s)
      Trijntje J. Pool
    • Journal Title

      Biomol. NMR Assign.

      Volume: 7 Pages: 97-100

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 1H, 13C, and 15N resonance assignment of photoactive yellow protein2012

    • Author(s)
      T. J. Pool, N. A. Oktaviani, H. Kamikubo, M. Kataoka, F. A. A. Mulder
    • Journal Title

      Biomol. NMR Assign

      Volume: 7 Pages: 97-100

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Maintenance of the secondary structure ofhorse cytochrome c during the conversion process of monomers to oligomers byaddition of ethanol2012

    • Author(s)
      S. Hirota, M. Ueda, Y. Hayashi, S. Nagao, H. Kamikubo, M. Kataoka
    • Journal Title

      J. Biochem

      Volume: 152 Pages: 521-529

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Time-resolved observation of chiral-index-selective wrapping on single-walled carbon nanotube with non-aromatic polysilane2012

    • Author(s)
      W. Chung, K. Nobusawa, H. Kamikubo, M. Kataoka, M. Fujiki, M. Naito
    • Journal Title

      J. Am. Chem. Soc

      Volume: 135 Pages: 2374-2383

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Theoretical analysis of the geometrical isotope effect on the hydrogen bonds in photoactive yellow protein with multi-component density functional theory2012

    • Author(s)
      Y. Kita, H. Kamikubo, M. Kataoka, M. Tachikawa
    • Journal Title

      Chem. Phys

      Volume: 419 Pages: 50-53

    • DOI

      10.1016/j.chemphys.2012.11.022

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Watching asignaling protein function in real time via100-ps time-resolved Laue crystallography2012

    • Author(s)
      F. Schotte, H. S. Cho, V. R. I. Kaila, H. Kamikubo, N. Dashdorj, E. R. Henry, T. J. Graber, R. Henning, M. Wulff, G. Hummer, M. Kataoka, P. A. Anfinrud
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109 Pages: 19256-19261

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural basis for Arf6.MKLP1 complexformation on the Flemming bodyresponsible for cytokinesis2012

    • Author(s)
      H. Makyio, M. Ohgi, T. Takei, S. Takahashi, H. Takatsu, Y. Katoh, A. Hanai, T. Ueda, Y. Kanaho, Y. Xie, H.-W. Shin, H. Kamikubo, M. Kataoka, M. Kawasaki, R. Kato, S. Wakatsuki, K. Nakayama
    • Journal Title

      EMBO J

      Volume: 31 Pages: 2590-2603

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 中性子生物物理学の展開2012

    • Author(s)
      片岡幹雄
    • Journal Title

      波紋

      Volume: 22 Pages: 132-138

    • NAID

      130007516782

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Journal Article] Watching a signaling protein function in real time via 100-ps time-resolved Laue crystallography2012

    • Author(s)
      Friedrich Schotte
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109 Pages: 19256-19261

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Maintenance of the secondary structure of horse cytochrome c during the conversion process of monomers to oligomers by addition of ethanol2012

    • Author(s)
      Shun Hirota
    • Journal Title

      J. Biochem.

      Volume: 152 Pages: 521-529

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time-resolved observation of chiral-index-selective wrapping on single-walled carbon nanotube with non-aromatic polysilane2012

    • Author(s)
      Woojung Chung
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 135 Pages: 2374-2383

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comprehensive determination of protein tyrosine pKa values for photoactive yellow protein using indirect ^<13>C NMR spectroscopy2012

    • Author(s)
      N.Alia Oktaviani
    • Journal Title

      Biophys.J.

      Volume: 102 Issue: 3 Pages: 579-586

    • DOI

      10.1016/j.bpj.2011.12.024

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comprehensivedetermination of protein tyrosine pKavalues for photoactive yellow protein usingindirect 13C NMR spectroscopy2011

    • Author(s)
      N. A. Oktaviani, T. J. Pool, H. Kamikubo, J. Slager, R. M. Scheek, M. Kataoka, F. A.A. Mulder
    • Journal Title

      Biophys. J

      Volume: 102 Pages: 579-586

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 生物研究における中性子2011

    • Author(s)
      片岡幹雄
    • Journal Title

      波紋

      Volume: 21 Pages: 243-246

    • NAID

      130007516830

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Solvent penetration in photoactive yellow protein R52Q mutant: a theoretical study2011

    • Author(s)
      D. J. Sindhikara, N. Yoshida, M. Kataoka, F. Hirata
    • Journal Title

      J. Mol. Liq

      Volume: 164 Pages: 120-122

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in the hydrogen-bondnetwork around the chromophore of photoactive yellow protein in the groundand excited states2011

    • Author(s)
      M. Mizuno, H. Kamikubo, M. Kataoka, Y. Mizutani
    • Journal Title

      J. Phys. Chem. B

      Volume: 115 Pages: 9306-9310

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 中性子非弾性散乱による生体高分子ダイナミックスの研究2011

    • Author(s)
      中川洋,片岡幹雄
    • Journal Title

      高分子

      Volume: 60 Pages: 195-196

    • NAID

      10027971886

    • Related Report
      2012 Final Research Report
  • [Journal Article] Changes in the Hydrogen-Bond Network around the Chromophore of Photoactive Yellow Protein in the Ground and Excited States2011

    • Author(s)
      Misao Mizuno, Hironari Kamikubo, Mikio Kataoka and Yasuhisa Mizutani
    • Journal Title

      J. Phys. Chem. B

      Volume: 115 Issue: 29 Pages: 9306-9310

    • DOI

      10.1021/jp2029399

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Solvent penetration in photoactive yellow protein R52Q mutant : a theoretical study2011

    • Author(s)
      Daniel, J.Sindhikara
    • Journal Title

      J.Mol.Liq.

      Volume: 164 Issue: 1-2 Pages: 120-122

    • DOI

      10.1016/j.molliq.2011.04.007

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 中性子弾性散乱による生体高分子ダイナミックスの研究2011

    • Author(s)
      中川洋, 片岡幹雄
    • Journal Title

      高分子

      Volume: 60 Pages: 195-196

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Systematic alanine insertion reveals the essential regions that encode structure formation and activity of dihydrofolate reductase2011

    • Author(s)
      Rumi Shiba
    • Journal Title

      BIOPHYSICS

      Volume: 7 Pages: 1-10

    • NAID

      130000406413

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Systematic alanine insertion reveals the essential regions that encode structure formation and activity of dihydrofolate reductase2010

    • Author(s)
      R. Shiba, M. Umeyama, S. Tsukasa, H. Kamikubo, Y. Yamazaki, M. Yamaguchi, M.Iwakura, M. Kataoka
    • Journal Title

      Biophysics

      Volume: 7 Pages: 1-10

    • NAID

      130000406413

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Percolation of hydration water as a control of protein dynamics2010

    • Author(s)
      H. Nakagawa, M. Kataoka
    • Journal Title

      J. Phys. Soc. Jpn

      Volume: 79 Pages: 83801-83801

    • NAID

      40017245105

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Size-controlled aggregation of cube-shaped EuS nanocrystals with magneto-opticproperties in solution phase2010

    • Author(s)
      A. Tanaka, H. Kamikubo, M. Kataoka, Y. Hasegawa, T. Kawai
    • Journal Title

      Langmuir

      Volume: 27 Pages: 104-108

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      S. Hirota, Y. Hattori, S. Nagao, M.Taketa, H. Komori, H. Kamikubo, Z. Wang, I. Takahashi, S. Negi, Y. Sugiura, M. Kataoka, Y. Higuchi
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 107 Pages: 12854-12859

    • NAID

      120005716875

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] フォトアクティブイェロープロテインの中性子結晶構造解析2010

    • Author(s)
      上久保裕生,山口繁生,片岡幹雄
    • Journal Title

      Radioisotopes

      Volume: 59 Pages: 289-297

    • NAID

      10026244827

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Percolation of hydration water as a control of protein dynamics.2010

    • Author(s)
      H.Nakagawa, M.Kataoka.
    • Journal Title

      J.Phys.Soc.Jpn 79

      Pages: 83801-83801

    • NAID

      40017245105

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease.2010

    • Author(s)
      S.Kato, H.Kamikubo, S.Hirano, Y.Yamazaki, M.Kataoka.
    • Journal Title

      Biophys.J. 98

      Pages: 678-786

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Effect of conformational states on protein dynamical transition2010

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      Biochim.Biophys.Acta

      Volume: 1804 Pages: 27-33

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease2010

    • Author(s)
      Shingo Kato
    • Journal Title

      Biophys.J.

      Volume: 98 Pages: 678-786

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-Assembly and Enhanced Magnetic Properties of Three-dimensional Superlattice Structures Composed of Cube- and Sphere-Shaped EuS Nanocrsytals2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Chem.Mat.

      Volume: 22 Pages: 1776-1781

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Shun Hirota
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: 107 Pages: 12854-12859

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Percolation of hydration water as a control of protein dynamics2010

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      J.Phys.Soc.Jpn

      Volume: 79 Pages: 83801-83801

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Size-controlled aggregation of cube-shaped EuS nanocrystals with magneto-optic properties in solution2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Langmuir

      Volume: 27 Pages: 104-108

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] フォトアクティブイェロープロテインの中性子結晶構造解析2010

    • Author(s)
      上久保裕生
    • Journal Title

      RADIOISOTOPES

      Volume: 59 Pages: 289-297

    • NAID

      10026244827

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Effect of conformational states on protein dynamical transition2010

    • Author(s)
      H.Nakagawa
    • Journal Title

      Biochim.Biophys.Acta 1804

      Pages: 27-33

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease2010

    • Author(s)
      Shingo Kato
    • Journal Title

      Biophys.J 98

      Pages: 678-686

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-assembling formation and enhanced magnetic properties of three-dimensional super-lattice structures composed of cube- and sphere-shaped EuS nanocrsytals2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Chemistry of Materials (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of conformational states on protein dynamical transition2009

    • Author(s)
      H. Nakagawa, H. Kamikubo, M. Kataoka
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1804 Pages: 27-33

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Self-assembly and enhanced magnetic properties of three-dimensional superlattice structures composed of cube-shaped EuS nanocrystals2009

    • Author(s)
      A. Tanaka, H. Kamikubo, Y. Doi, Y. Hinatsu, M. Kataoka, T. Kawai, Y. Hasegawa
    • Journal Title

      Chem. Mater

      Volume: 22 Pages: 1776-1781

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nonlocal interactions are responsible for tertiary structure formation in staphylococcalnuclease2009

    • Author(s)
      S. Kato, H. Kamikubo, S. Hirano, Y.Yamazaki, M. Kataoka
    • Journal Title

      Biophys. J

      Volume: 98

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Self-aggregation of magnetic semiconductor EuS nanocrystals2009

    • Author(s)
      Tanaka, Y. Hasegawa, H. Kamikubo, M. Kataoka, T. Kawai
    • Journal Title

      Thin Solid Films

      Volume: 518 Pages: 870-872

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural effects on the ultrafast photoisomerization of photoactive yellowprotein. Transient absorption spectroscopy of two point mutants2009

    • Author(s)
      P. Changenet-Barret, P. Plaza, M. M. Martin, H. Chosrowjan, S. Taniguchi, N. Mataga, Y. Imamoto, M. Kataoka
    • Journal Title

      J. Phys. Chem. C

      Volume: 113 Pages: 11605-11613

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 非干渉性中性子非弾性散乱で観るタンパク質ダイナミクスの水和効果2009

    • Author(s)
      中川洋,片岡幹雄
    • Journal Title

      波紋

      Volume: 19 Pages: 91-94

    • NAID

      130006701975

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Low barrier hydrogen bond in photoactive yellow protein.2009

    • Author(s)
      S.Yamaguchi, H.Kamikubo, K.Kurihara, R.Kuroki, N.Niimura, N.Shimizu, Y.Yamazaki, M.Kataoka.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 106

      Pages: 440-444

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Structural effects on the ultrafast photoisomerization of photoactive yellow protein : Transient absorption spectroscopy of two point mutants2009

    • Author(s)
      Pascale Changenet-Barret
    • Journal Title

      J.Phys.Chem.C. 113

      Pages: 11605-11613

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-aggregation of magnetic semiconductor EuS nanocrystals2009

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Thin Solid Films 518

      Pages: 870-872

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low barrier hydrogen bond in photoactive yellow protein2009

    • Author(s)
      Shigeo Yamaguchi
    • Journal Title

      Proceedings of the National Academy of Science of USA 106

      Pages: 440-444

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nucleotide-dependentconformational changes and assembly of the AAA ATPase SKD1/VPS4B2008

    • Author(s)
      M. Inoue, H. Kamikubo, M. Kataoka,Ryuichi Kato, T. Yoshimori, S. Wakatsuki, M. Kawasaki
    • Journal Title

      Traffic

      Volume: 9 Pages: 2180-2189

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Low-barrier hydrogen bond in photoactiveyellow protein2008

    • Author(s)
      S. Yamaguchi, H. Kamikubo, K. Kurihara, R. Kuroki, N. Niimura, N. Shimizu, Y. Yamazaki, M. Kataoka
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 106 Pages: 440-444

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diverse Roles of Glycine Residues Conserved in Photoactive Yellow Proteins2008

    • Author(s)
      Yasushi Imamoto
    • Journal Title

      Biophysical Journal 94

      Pages: 3620-3628

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of the N-terminal region in the function of the photosynthetic bacterium transcription regulator PpsR2008

    • Author(s)
      Yoichi Yamazaki
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 839-844

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanism of induced folding : Both folding before binding andbinding before folding can be realized in staphylococcal nuclease mutants2008

    • Author(s)
      Masayoshi, Onitsuka
    • Journal Title

      Proteins : Structures, Functions and Bioinformatics 72

      Pages: 837-847

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hydration effects on low-frequency protein dynamics observed in simulated neutron scattering spectra2008

    • Author(s)
      Yasumasa Joti
    • Journal Title

      Biophysical Journal 94

      Pages: 4435-4443

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The photoreaction of the photoactive yellow protein domain in the light sensor histidine kinase Par is influenced by the C-terminal domains2008

    • Author(s)
      Hironari Kamikubo
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 895-902

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low-temperature spectroscopy of Met100Ala mutant of photoactive yellow protein2008

    • Author(s)
      Yasushi Imamoto
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 970-976

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction between N-terminal loop and β-scaffold of photoactive yellow protein2008

    • Author(s)
      Miki Harigai
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 1031-1037

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hydration affects both harmonic and anharmonic nature of protein dynamics2008

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      Biophysical Journal 95

      Pages: 2916-2923

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B2008

    • Author(s)
      Michio Inoue
    • Journal Title

      Traffic 9

      Pages: 2180-2189

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] イェロープロテインの光反応中の構造変化を見る2013

    • Author(s)
      片岡幹雄
    • Organizer
      日本物理学会第68回年次大会
    • Place of Presentation
      広島県東広島市
    • Year and Date
      2013-03-26
    • Related Report
      2012 Annual Research Report
  • [Presentation] Is tertiary structure really required for specific function of a protein?2013

    • Author(s)
      片岡幹雄
    • Organizer
      American Physical Society (APS) March Meeting 2013
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2013-03-22
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Is the protein tertiary structure necessary for a specific function?2013

    • Author(s)
      片岡幹雄
    • Organizer
      International Symposium on Protein Folding and its Biological Significance
    • Place of Presentation
      愛知県岡崎市
    • Year and Date
      2013-03-14
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Structure and photoreaction of photoactive yellow protein2013

    • Author(s)
      片岡幹雄
    • Organizer
      The 4th Japan-France Joint Symposium “Imaging of spatiotemporal hierarchies in living cells -An overview of dynamics from molecules to cells-“
    • Place of Presentation
      兵庫県佐用郡
    • Year and Date
      2013-01-10
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Is the protein tertiary structure necessary for a specificfunction?2013

    • Author(s)
      M. Kataoka
    • Organizer
      American Physical Society (APS)March Meeting 2013
    • Place of Presentation
      Baltimore, MD, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Structure, dynamics and function of staphylococcal nuclease2012

    • Author(s)
      片岡幹雄
    • Organizer
      The 6th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      京都府京都市
    • Year and Date
      2012-12-06
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Effect of hydration on protein dynamics2012

    • Author(s)
      片岡幹雄
    • Organizer
      The 6th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      京都府京都市
    • Year and Date
      2012-12-05
    • Related Report
      2012 Annual Research Report
  • [Presentation] Protein dynamics and hydration water2012

    • Author(s)
      片岡幹雄
    • Organizer
      10th International Conference on Quasielastic Neutron Scattering
    • Place of Presentation
      栃木県日光市
    • Year and Date
      2012-10-04
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 水和がタンパク質動力学に与える影響2012

    • Author(s)
      片岡幹雄
    • Organizer
      新学術領域研究合同公開シンポジウム「ゆらぎと水-生命のエネルギーと機能の分子機構を探る」
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2012-09-14
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular Anatomy of Staphylococcal Nuclease2012

    • Author(s)
      Mikio Kataoka
    • Organizer
      4th Japan-Korea Seminar on Biomolecular Sciences : Experiments and Simulations
    • Place of Presentation
      奈良市(招待講演)
    • Year and Date
      2012-01-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Incorporation of Fluorescent Non-natural Amino Acids into Staphylococcal Nuclease for FRET Analyses of Induced Folding2012

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Study on the Denatured Structure of Staphylococcal Nuclease by Using Tryptophan Triplet State Quenching2012

    • Author(s)
      Mariko Yamaguchi
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Comparison of Structural Elements between Staphylococcal Nuclease and the C-terminal Domain of Human p1002012

    • Author(s)
      Sho Ueyanagi
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Attempt of Functional Modification of a Protein by Element Implantation2012

    • Author(s)
      Eri Sakai
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Denatured Structure of Staphylococcal Nuclease Studied by Quenching of Tryptophan Triplet State by Cysteine2012

    • Author(s)
      Toshihiro Okada
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] The Roles of the Low Barrier Hydrogen Bond Involved in the Light Sensor Protein, Photoactive Yellow Protein2012

    • Author(s)
      Hironari Kamikubo
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Refinement of Function Element of Dihydrofolate Reductase by the Systematic Alanine Insertion2012

    • Author(s)
      Rumi Shiba
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] The Role of N-terminal Region for Photoreaction of Various Photoactive Yellow Proteins2012

    • Author(s)
      Ryota Odani
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Geometric Restriction Facilitates LBHB Formation in Photoactive Yellow Protein2012

    • Author(s)
      Yusuke Nishiguchi
    • Organizer
      The 5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
    • Place of Presentation
      奈良市
    • Year and Date
      2012-01-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Protein dynamics and hydration water2012

    • Author(s)
      M. Kataoka
    • Organizer
      The 10th International Conference on Quasi Elastic Neutron Scattering
    • Place of Presentation
      Nikko
    • Related Report
      2012 Final Research Report
  • [Presentation] The formation and role of low barrier hydrogen bond in photoactive yellow protein2011

    • Author(s)
      Mikio Kataoka
    • Organizer
      物構研シンポジウム'11量子ビーム化学の展望
    • Place of Presentation
      つくば市(招待講演)
    • Year and Date
      2011-12-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Physicochemical properties of low barrier hydrogen bonds involved in Photoactive Yellow Protein2011

    • Author(s)
      Hironari Kamikubo
    • Organizer
      1st Asia-Oceania Conference on Neutron Scattering
    • Place of Presentation
      つくば市(招待講演)
    • Year and Date
      2011-11-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] The roles of the low barrier hydrogen bond involved in Photoactive Yellow Protein2011

    • Author(s)
      Hironari Kamikubo
    • Organizer
      17th International Biophysics Congress (IUPAB)
    • Place of Presentation
      Beijing, China
    • Year and Date
      2011-11-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] Refinement of function element of dihydrofolate reductase by the systematic alanine insertion2011

    • Author(s)
      Rumi Shiba
    • Organizer
      17th International Biophysics Congress (IUPAB)
    • Place of Presentation
      Beijing, China
    • Year and Date
      2011-10-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] Local structural change of staphylococcal nuclease wild type and its non-native mutant with guanidine hydrochloride monitored by tryptophan triplet quenching2011

    • Author(s)
      Mariko Yamaguchi
    • Organizer
      17th International Biophysics Congress (IUPAB)
    • Place of Presentation
      Beijing, China
    • Year and Date
      2011-10-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] Comparison of structural elements between Staphylococcal nuclease and the C-terminal domain of Human p1002011

    • Author(s)
      Sho Ueyanagi
    • Organizer
      17th International Biophysics Congress (IUPAB)
    • Place of Presentation
      Beijing, China
    • Year and Date
      2011-10-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] タンパク質動力学と水和2011

    • Author(s)
      片岡幹雄
    • Organizer
      日本分光学会テラヘルツ分光部会シンポジウム「テラヘルツ分光法の最先端V」~バイオテラヘルツ分光~
    • Place of Presentation
      横浜市(招待講演)
    • Year and Date
      2011-09-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Solution structure of the complex states of Rhodobacter capsulatus PYP with its binding protein2011

    • Author(s)
      Yoichi Yamazaki
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Analysis of low barrier hydrogen bond in Photoactive Yellow Protein, Geometric restriction facilitates LBHB formation in PYP2011

    • Author(s)
      Yusuke Nishiguchi
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] The Role of N-terminal Region for Photoreaction of Various Photoactive Yellow Proteins2011

    • Author(s)
      Ryota Odani
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of light dependent protein activity control system by use of interaction of the Rc-PYP2011

    • Author(s)
      Shinya Setoguchi
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Structural Analysis of Intrinsically Disordered Protein Model using FRET2011

    • Author(s)
      Takuya Muto
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Attempt of functional modification of a protein by element implantation2011

    • Author(s)
      Eri Sakai
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Denatured Structure of Staphylococcal Nuclease Studied by Triplet State Quenching of Tryptophan by Cysteine2011

    • Author(s)
      Toshihiro Okada
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Cytochrome c polymerization by domain swapping2011

    • Author(s)
      Satoshi Nagao
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Difference in local structure between staphylococcal nuclease wild type and its non-native mutant studied by tryptophan triplet quenching2011

    • Author(s)
      Mariko Yamaguchi
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Classification of function element of dihydrofolate reductase by the systematic alanine insertion2011

    • Author(s)
      Rumi Shiba
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Comparison of structural elements between Staphylococcal nuclease and the C-terminal domain of Human p1002011

    • Author(s)
      Sho Ueyanagi
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Is tertiary structure required for a specific function?2011

    • Author(s)
      Mikio Kataoka
    • Organizer
      Telluride Conference on Protein Dynamics 2011
    • Place of Presentation
      Telluride, USA(招待講演)
    • Year and Date
      2011-08-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] High resolution neutron crystallography of photoactive yellow protein-Discovery of low barrier hydrogen bond2011

    • Author(s)
      Mikio Kataoka
    • Organizer
      第3回韓日生体分子科学セミナー
    • Place of Presentation
      Cheju-do, Korea(招待講演)
    • Year and Date
      2011-02-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] High resolution neutron crystal structure of photoactive yellow protein : Discovery of low barrier hydrogen bond2011

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 7th Asian Biophysics Association (ABA) Symposium
    • Place of Presentation
      New Delhi, India(招待講演)
    • Year and Date
      2011-02-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Is tertiary structure required for a specific function?2011

    • Author(s)
      M. Kataoka
    • Organizer
      Telluride Science Research Center (TSRC) Workshopon Protein Dynamics 2011
    • Place of Presentation
      Telluride, CO,USA
    • Related Report
      2012 Final Research Report
  • [Presentation] High resolution neutron crystal structure of photoactive yellow protein: Discovery of low barrierhydrogen bond2011

    • Author(s)
      M. Kataoka
    • Organizer
      The 7th Asian BiophysicsAssociation (ABA) Symposium
    • Place of Presentation
      New Delhi,India
    • Related Report
      2012 Final Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, U.S.A.(招待講演)
    • Year and Date
      2010-12-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Fluctuation controls enzymatic activity of Staphylococcal nuclease2010

    • Author(s)
      Hironari Kamikubo
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津市
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase by the systematic alanine insertion2010

    • Author(s)
      Rumi Shiba
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津市
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] FRET analysis of structural changes in staphylococcal nuclease2010

    • Author(s)
      Yusuke Kishi
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津市
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Zhonghua Wang
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津市
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease2010

    • Author(s)
      Hiroki Sawada
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津市
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Measurements of loop formation in the denatured state of staphylococcal nuclease2010

    • Author(s)
      Mariko Yamaguchi
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津市
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 中性子非弾性散乱と分子動力学によるタンパク質の揺らぎと水和水ダイナミクスの研究2010

    • Author(s)
      中川洋
    • Organizer
      日本物理学会2010年秋季大会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛋白質機能の発現に構造は必須か?2010

    • Author(s)
      片岡幹雄
    • Organizer
      日本物理学会2010年秋季大会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-09-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Shun Hirota
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] A case of EspB from enterohaemorrhagic Escherichia coli2010

    • Author(s)
      Daizo Hamada
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Property of a structural element of SNase-like domain in human p1002010

    • Author(s)
      Yoko Ogawa
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease2010

    • Author(s)
      Hiroki Sawada
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] FRET analysis of structural changes in Staphylococcal nuclease2010

    • Author(s)
      Yusuke Kishi
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] The mechanism of induced folding of Staphylococcal nuclease : Folding before binding or binding before folding?2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市(招待講演)
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effects of trehalose on the structures and dynamics of lipid membrane2010

    • Author(s)
      Tomomi Masui
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Solution structure of the light sensor histidine kinase of Ppr comprised of the PYP and Bph domains2010

    • Author(s)
      Junko Miura
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Solution structural analysis of Drosophila GGA2010

    • Author(s)
      Maiko Naruse
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Analysis of solution state of the interaction protein of Rc-PYP2010

    • Author(s)
      Miki Hayashi
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] The role of each residue in the fiexible Ω loop of Staphylococcal nuclease on the catalytic activity2010

    • Author(s)
      Changjun Ahn
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase (DHFR) by the systemic alanine insertion2010

    • Author(s)
      Rumi Shiba
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of an artificial enzyme by implanting the functional elements of SNase2010

    • Author(s)
      Hironari Kamikubo
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Urea denaturation of staphylococcal nuclease monitored by tryptophan-cysteine distance2010

    • Author(s)
      Mariko Yamaguchi
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Substitution effects of basic residues in the photoactive yellow protein of Rhodobacter caplsulatus2010

    • Author(s)
      Yoichi Yamazaki
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Photoactive Yellow Proteinにおける発色団の機能変調2010

    • Author(s)
      山崎洋一
    • Organizer
      第16回日本光生物学協会年会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-08-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of hydration water on protein dynamics2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China(招待講演)
    • Year and Date
      2010-08-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] The effect of alanine insertion mutation for folding process2010

    • Author(s)
      Hiroki Sawada
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Year and Date
      2010-08-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Extraction of the regions encoded foldability and/or functionability from dihydrofolate reductase by the systematic alanine insertion2010

    • Author(s)
      Rumi Shiba
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Year and Date
      2010-08-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 精子由来蛋白質IZUMO,その構造と受精膜融合での役割2010

    • Author(s)
      萩原義久
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌市
    • Year and Date
      2010-06-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出2010

    • Author(s)
      芝るみ
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌市
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of hydration on protein dynamics2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      Leopoldina-Symposium on the Complexity Connecting Biomolecular Structure and Solvation Dynamics
    • Place of Presentation
      Bochum, Germany(招待講演)
    • Year and Date
      2010-05-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Low barrier hydrogenbond in photoactive yellow protein and itsrole in photoreaction2010

    • Author(s)
      M. Kataoka
    • Organizer
      International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, U. S. A.
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of hydration water on protein dynamics2010

    • Author(s)
      M. Kataoka
    • Organizer
      The 4th Shangai International Conference on Biophysics and Molecular Biology(2010SICBM)
    • Place of Presentation
      Shanghai-Jiashan, China
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of hydration on protein dynamics2010

    • Author(s)
      M. Kataoka
    • Organizer
      Leopoldina-Symposium on the ComplexityConnecting Biomolecular Structure and Solvation Dynamics
    • Place of Presentation
      Bochum, Germany
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of hydration on protein dynamics.2010

    • Author(s)
      M.Kataoka.
    • Organizer
      Leopoldina-Symposium on the Complexity Connecting Biomolecular Structure and Solvation Dynamics.
    • Place of Presentation
      Bochum, Germany
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Structure and photoreaction of photoactive yellow protein : Direct observation of low barrier hydrogen bond and its roles2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      ATI International Forum 2009, "Protein Structure Determination and Applications"
    • Place of Presentation
      東海
    • Year and Date
      2009-03-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] Mechanism of Induced Folding of Staphylococcal Nuclease : Implication to Natively Unfolding Protein2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 6th Asian Biophysics Association (ABA) Symposium
    • Place of Presentation
      香港(中国)
    • Year and Date
      2009-01-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2009

    • Author(s)
      M. Kataoka
    • Organizer
      Telluride Science Research Center (TSRC) Workshop on Protein Dynamics 2009
    • Place of Presentation
      Telluride, CO, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] タンパク質動力学に対する水和の効果2009

    • Author(s)
      片岡幹雄
    • Organizer
      第9回日本蛋白質科学会年会
    • Place of Presentation
      熊本
    • Related Report
      2009 Annual Research Report
  • [Presentation] イェロープロテインの低障壁水素結合の形成とその役割2009

    • Author(s)
      片岡幹雄
    • Organizer
      第36回生体分子化学討論会
    • Place of Presentation
      札幌
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      Telluride Science Research Center (TSRC) Work shop on Protein Dynamics 2009
    • Place of Presentation
      テルライド(アメリカ)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of Hydration Water on Protein Dynamics2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 3rd UT Horiba International Symposium on Hydrogen and water in condensed matter physics
    • Place of Presentation
      千葉
    • Related Report
      2009 Annual Research Report
  • [Presentation] Photoactive Yellow Proteinの低障壁水素結合2009

    • Author(s)
      山口繁生
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 中性子非弾性散乱で蛋白質の熱揺らぎを測る2009

    • Author(s)
      片岡幹雄
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rc-PYPと相互作用タンパク質を用いた酵素活性の光制御系の作製2009

    • Author(s)
      久保晴政
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rhodobacter capsulatus由来PYPの相互作用様式の解析2009

    • Author(s)
      山崎洋一
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rc-PYPの低温分光2009

    • Author(s)
      濱口祐也
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] キメラを用いたPhotoactive Yellow Proteinの研究2009

    • Author(s)
      松本啓佑
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Staphylococcal nucleaseアラニン挿入変異体の結晶学的研究2009

    • Author(s)
      吉岡紘志
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] エレメント置換による蛋白質の機能獲得の試み2009

    • Author(s)
      小賀坂彰浩
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] アゾベンゼンを用いた構造エレメントのモジュレーション2009

    • Author(s)
      齊藤謙介
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 誘導折り畳み反応のΦ値解析:スタフィロコッカルヌクレアーゼ変異体の誘導折り畳み反応におけるリガンド結合の役割2009

    • Author(s)
      鬼塚正義
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 電子常磁性共鳴分光法による天然変性Staphylococcal nuclease変異体の構造解析2009

    • Author(s)
      澤田宏起
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現および構造形成領域の抽出2009

    • Author(s)
      芝るみ
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析によるHuman p100 SNase様ドメインの構造形成に関わる領域の抽出2009

    • Author(s)
      小川洋子
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 蛋白質の調和運動と非調和運動に対する水和効果2009

    • Author(s)
      中川洋
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 1st NCTU-NAIST workshop on "Molecular/Nano Science"
    • Place of Presentation
      新竹(台湾)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 中性子結晶構造解析による蛋白質中の「低障壁」水素結合の発見2009

    • Author(s)
      上久保裕生
    • Organizer
      第9回日本中性子科学会年会
    • Place of Presentation
      茨城
    • Related Report
      2009 Annual Research Report
  • [Presentation] 蛋白質動力学転移における水和水の構造とダイナミクス2008

    • Author(s)
      中川洋
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] 光受容タンパク質AppAの分子内相互作用機構2008

    • Author(s)
      中西勇人
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] Human p100のSNase様ドメインの折れ畳み能2008

    • Author(s)
      米田知可子
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法によるジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出2008

    • Author(s)
      芝るみ
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 拡散係数変化によるPYPの光反応における構造変化の起源の検討2008

    • Author(s)
      Javaid Shahbaz Khan
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] Photoactive yellow proteinの構造および機能エレメントの同定2008

    • Author(s)
      山田好輝
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 核酸分解酵素におけるループの揺らぎと機能の関係2008

    • Author(s)
      田所成文
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] L1M08が担うStaphylgcoccal Nucleaseの折り畳寿における役割の解明2008

    • Author(s)
      中垣礼寧
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] アラニン挿入変異がキネティクスに与える影響2008

    • Author(s)
      澤田宏起
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Rhodobacter capsulatus由来PYPの複合体状態における分光学的特長2008

    • Author(s)
      山崎洋一
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] 光センサー型ヒスチジンキナーゼPYPドメインの光反応に対するC末端ドメインの影響2008

    • Author(s)
      上久保裕生
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Rc-PYPにおけるN末端部位の役割2008

    • Author(s)
      太田成人
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Photoactive Yellow Protein中の2種のshort hydrogen bondの直接観察2008

    • Author(s)
      山口繁生
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of hydration water on protein dynamics2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      150th Anniversary of Japan-France Relation-ship Workshop on Water & Cell Physiology
    • Place of Presentation
      京都
    • Year and Date
      2008-11-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of hydration on the glass-like transition of protein2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      Japan-France Bilateral Joint Seminar 2008 "Fron tiers of Glassy Physics"
    • Place of Presentation
      京都
    • Year and Date
      2008-11-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Protein Dynamics and Structure Studied by Neutron Scattering2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      Asia Science Seminar on "Frontier Science at High-Intensity Proton Accelerators"
    • Place of Presentation
      北京(中国)
    • Year and Date
      2008-10-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of hydration and conformational state on protein dynamics2008

    • Author(s)
      Maio Kataoka
    • Organizer
      Workshop Biomolecular Dynamics and Protein-Water Interactions
    • Place of Presentation
      ミュンヘン(ドイツ)
    • Year and Date
      2008-09-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] Staphylococcal nucleaseの誘導折り畳み機構2008

    • Author(s)
      片岡幹雄
    • Organizer
      第8回日本蛋白質科学会年会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-10
    • Related Report
      2008 Annual Research Report
  • [Book] 生体分子の動きを探る-揺らぎと生体機能-2013

    • Author(s)
      片岡幹雄
    • Publisher
      化学同人
    • Related Report
      2012 Annual Research Report
  • [Book] ひかりエネルギー革命-グリーンフォトニクス-(NAISTグリーンフォトニクス研究チーム編著)2012

    • Author(s)
      片岡幹雄
    • Publisher
      化学同人,京都
    • Related Report
      2012 Final Research Report
  • [Book] ひかりエネルギー革命-グリーンフォトニクス-2012

    • Author(s)
      片岡幹雄
    • Total Pages
      121
    • Publisher
      化学同人
    • Related Report
      2012 Annual Research Report
  • [Book] Neutrons in Soft Matter (Eds.T. Imae, T. Kanaya, M.Furusaka, N. Torikai)2011

    • Author(s)
      M. Kataoka, H. Nakagawa
    • Publisher
      John Wiley, NewJersey
    • Related Report
      2012 Final Research Report
  • [Book] Water, The Forgotten Biological Molecule(eds.by Denis Le Bihan and Hidenao Fukuyama)2011

    • Author(s)
      M.Kataoka, H.Nakagawa.
    • Publisher
      Pan Stanford Publishing (Singapore)
    • Related Report
      2010 Self-evaluation Report
  • [Book] Water, The Forgotten Biological Molecule2011

    • Author(s)
      Mikio Kataoka
    • Publisher
      Pan Stanford Publishing
    • Related Report
      2010 Annual Research Report
  • [Book] 揺らぎと生体機能(MedicalBio 10月別冊)2011

    • Author(s)
      片岡幹雄
    • Publisher
      オーム社
    • Related Report
      2010 Annual Research Report
  • [Book] 光ナノ科学への招待2011

    • Author(s)
      片岡幹雄
    • Publisher
      化学同人
    • Related Report
      2010 Annual Research Report
  • [Book] Neutrons in Soft Matter2011

    • Author(s)
      Mikio Kataoka
    • Publisher
      John Wiley
    • Related Report
      2010 Annual Research Report
  • [Book] 揺らぎと生体機能 (MedicalBio 10月別冊)(寺嶋正秀監修)2010

    • Author(s)
      片岡幹雄
    • Publisher
      オーム社,東京
    • Related Report
      2012 Final Research Report
  • [Book] 光ナノ科学への招待(長谷川靖哉、細川陽一郎、中嶋琢也編)2010

    • Author(s)
      片岡幹雄
    • Publisher
      化学同人,京都
    • Related Report
      2012 Final Research Report
  • [Book] Water, The Forgotten Biological Molecule (Eds. D. LeBihan, H. Fukuyama)2010

    • Author(s)
      M. Kataoka, H. Nakagawa
    • Publisher
      Pan Stanford Publishing, Singapore
    • Related Report
      2012 Final Research Report
  • [Book] Protein dynamics studied by neutron incoherent scattering2010

    • Author(s)
      Mikio Kataoka
    • Publisher
      John Wiley(in press)
    • Related Report
      2009 Annual Research Report
  • [Book] Water andBiomolecules (Eds. K. Kuwajima, Y. Goto, F.Hirata, M. Kataoka, M. Terazima)2009

    • Author(s)
      M. Kataoka, H. Kamikubo
    • Publisher
      Springer-Verlag, Berlin
    • Related Report
      2012 Final Research Report
  • [Book] 光科学研究の最前線 2(「光科学研究の最前線 2」編集委員会編2009

    • Author(s)
      片岡幹雄
    • Total Pages
      208
    • Publisher
      強光子場科学研究懇談会,東京
    • Related Report
      2012 Final Research Report
  • [Remarks] (1)光センサータンパク質の構造変化を世界最高レベルの分解能で可視化することに成功(MSN産経ニュース「ベテラン記者のデイリーコラム・坂口至徳の科学の現場を歩く」2012年11月6日、日刊工業新聞 2012年11月7日、日経新聞 2012年11月27日)

    • Related Report
      2012 Final Research Report
  • [Remarks] (2)日本中性科学会第 9回学会賞を受賞(科学新聞 2011年11月18日)

    • Related Report
      2012 Final Research Report
  • [Remarks] (3) M. Terazima, M. Kataoka and R. Ueoka, "Molecular Science of Fluctuations toward Biological Functions",(Science, 333, 1329. 2011年9月2日)

    • Related Report
      2012 Final Research Report
  • [Remarks] (4)タンパク質動力学に対する水和水の役割を解明(科学新聞 2010年8月6日、日経産業新聞 2010年8月16日、日刊工業新聞 2010年8月23日)

    • Related Report
      2012 Final Research Report
  • [Remarks] (5)世界で初めてタンパク質に低障壁水素結合を発見(時事通信 2008年12月30日、産経新聞2008年12月31日、奈良日日新聞2009年1月5日、日刊工業新聞2009年1月6日、フジサンケイビジネスアイ2009年1月6日、科学新聞 2009年1月16日)

    • Related Report
      2012 Final Research Report

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Published: 2008-04-01   Modified: 2018-03-28  

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