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Regulation of Nucleo-cytoplasmic Distribution of RNAs

Planned Research

Project AreaDiversity and asymmetry achieved by RNA program
Project/Area Number 20112007
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionKyoto University

Principal Investigator

OHNO Mutsuhito  京都大学, ウイルス研究所, 教授 (80201979)

Project Period (FY) 2008 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥105,690,000 (Direct Cost: ¥81,300,000、Indirect Cost: ¥24,390,000)
Fiscal Year 2012: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2011: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2010: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2009: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2008: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
KeywordsRNA / 輸送 / 核 / 細胞質 / 識別
Research Abstract

We have shown that the tetramer of hnRNP C measures the length of the RNA polymerase II transcripts, like a molecular ruler, and classifies them into either mRNA or U snRNA according to their lengths. We have also revealed factors involved in the nuclear retention of pre-mRNAs in mammalian cells. Furthermore, we have obtained new insights in the area of RNA export.

Report

(7 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (140 results)

All 2013 2012 2011 2010 2009 2008

All Journal Article (33 results) (of which Peer Reviewed: 22 results,  Open Access: 1 results) Presentation (107 results) (of which Invited: 1 results)

  • [Journal Article] hDbr1 is a nucleocytoplasmic shuttling protein with a protein phosphatase-like motif essential for debranching activity2013

    • Author(s)
      Kataoka, N. Hagiwara, M. and Ohno, M
    • Journal Title

      Sci. Rep

      Volume: 3-1090 Issue: 1 Pages: 1090-1090

    • DOI

      10.1038/srep01090

    • NAID

      120005241441

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Size matters in RNA export2012

    • Author(s)
      Ohno, M
    • Journal Title

      RNA Biology

      Volume: 9(12) Issue: 12 Pages: 1-5

    • DOI

      10.4161/rna.22569

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: potential unusual mechanism identifies G-rich introns2012

    • Author(s)
      Sasaki-Haraguchi N, Shimada MK, Taniguchi I, Ohno M, Mayeda A
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 423(2) Issue: 2 Pages: 289-94

    • DOI

      10.1016/j.bbrc.2012.05.112

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 40S subunit dissociation and proteasome-dependent RNA degradation in nonfunctional 25S rRNA decay2012

    • Author(s)
      Fujii,K., Sakata,T., Kitabatake,M. and Ohno, M
    • Journal Title

      The EMBO Journa

      Volume: 31 Issue: 11 Pages: 2579-2589

    • DOI

      10.1038/emboj.2012.85

    • NAID

      120005122255

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export2012

    • Author(s)
      McCloskey,A. Taniguchi,I,. Shinmyozu, K, and Ohno, M
    • Journal Title

      Science

      Volume: 30 Pages: 1643-1646

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export2012

    • Author(s)
      McCloskey, A
    • Journal Title

      Science

      Volume: 335 Issue: 6076 Pages: 1643-46

    • DOI

      10.1126/science.1218469

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple factors in the early splicing complex are involved in the nuclear retention of pre-mRNAs in mammalian cells2011

    • Author(s)
      Takemura,R., Takeiwa,T,. McCloskey, A.,Taniguchi,I. and Ohno, M
    • Journal Title

      Genes Cells

      Volume: 16(10) Pages: 1035-49

    • NAID

      120005593652

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Specific Y14 domains mediate its nucleo- cytoplasmic shuttling and association with spliced mRNA2011

    • Author(s)
      Kataoka, N., Diem, M. D., Yoshida, M., Hatai, C., Dobashi, I., Dreyfuss, G., Hagiwara, M. and Ohno, M
    • Journal Title

      Sci. Rep

      Volume: 1 Issue: 1 Pages: 92-92

    • DOI

      10.1038/srep00092

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple factors in the early splicing complex are involved in the puclear retention of pre-mRNAs in mammalia cells2011

    • Author(s)
      Takemura, R
    • Journal Title

      Genes Cells

      Volume: 16(10) Pages: 1035-49

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cajal body surveillance of U snRNA export complex assembly2010

    • Author(s)
      Suzuki, T., Izumi, H. and Ohno, M
    • Journal Title

      J. Cell Biol

      Volume: 190 Issue: 4 Pages: 603-612

    • DOI

      10.1083/jcb.201004109

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cajal body surveillance of U snRNA export complex assembly.2010

    • Author(s)
      Suzuki, T., Izumi, H., Ohno, M.
    • Journal Title

      J.Cell Biol 190

      Pages: 603-612

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] RNAサーベイランス-RNA-タンパク質複合体の品質管理2010

    • Author(s)
      大野睦人
    • Journal Title

      実験医学

      Volume: Vol.28.No.16 Pages: 2611-2617

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Cajal body surveillance of U snRNA export complex assembly2010

    • Author(s)
      Suzuki, T
    • Journal Title

      J.Cell Biol

      Volume: 190:4 Pages: 603-612

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 真核生物リボソームの生合成と品質管理2010

    • Author(s)
      北畠真
    • Journal Title

      実験医学

      Volume: Vol.28.No.10 Pages: 150-155

    • Related Report
      2010 Annual Research Report
  • [Journal Article] A role for ubiquitin in the clearance of nonfunctional rRNAs2009

    • Author(s)
      Fujii, K., Sakata, T.,Kitabatake, M. and Ohno, M
    • Journal Title

      Genes Dev

      Volume: 23 Issue: 8 Pages: 963-74

    • DOI

      10.1101/gad.1775609

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functional association of the microprocessor complex with the spliceosome2009

    • Author(s)
      Kataoka, N., Fujita, M. and Ohno, M
    • Journal Title

      Mol. Cell. Biol

      Volume: 29 Issue: 12 Pages: 3243-54

    • DOI

      10.1128/mcb.00360-09

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] U1-independent pre-mRNA splicing contributes to the regulation of alternative Splicing2009

    • Author(s)
      Fukumura,K,. Taniguchi, I,. Sakamoto, H,. Ohno, M and Inoue,I
    • Journal Title

      Nucleic Acids Res

      Volume: Vol.37, No.6 Issue: 6 Pages: 1907-1914

    • DOI

      10.1093/nar/gkp050

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and characterization of postsplicing lariat-intron complexes2009

    • Author(s)
      Yoshimoto, R., Kataoka, N., Okawa, K. and Ohno,M
    • Journal Title

      Nucleic Acids Res

      Volume: 37 Issue: 3 Pages: 891-902

    • DOI

      10.1093/nar/gkn1002

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A role for ubiquitin in the clearance of nonfunctional rRNAs.2009

    • Author(s)
      Fujii, K., Sakata, T., Kitabatake, M., Ohno, M.
    • Journal Title

      Genes Dev. 23

      Pages: 963-974

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Functional association of the microprocessor complex with the spliceosome.2009

    • Author(s)
      Kataoka, N., Fujita, M., Ohno, M.
    • Journal Title

      Mol.Cell.Biol. 29

      Pages: 3243-3254

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 核-細胞質問のRNA分配制御2009

    • Author(s)
      大野睦人
    • Journal Title

      蛋白質 核酸 酵素 Vol54. No.16

      Pages: 2114-2122

    • Related Report
      2009 Annual Research Report
  • [Journal Article] イントロンの代謝機構2009

    • Author(s)
      片岡直行
    • Journal Title

      蛋白質 核酸 酵素 Vol54. No.16

      Pages: 2060-2065

    • Related Report
      2009 Annual Research Report
  • [Journal Article] リボソームRNAの品質管理2009

    • Author(s)
      北畠真
    • Journal Title

      蛋白質 核酸 酵素 Vol54. No.16

      Pages: 2195-2200

    • Related Report
      2009 Annual Research Report
  • [Journal Article] A role for ubiquitin in the clearance of nonfunctional rRNAs2009

    • Author(s)
      Fujii, K
    • Journal Title

      Genes Dev 23

      Pages: 963-974

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Functional association of the microprocessor complex with the spliceosome2009

    • Author(s)
      Kataoka, N
    • Journal Title

      Mol.Cell.Biol 29

      Pages: 3243-3254

    • Related Report
      2009 Annual Research Report
  • [Journal Article] U1-independent pre-mRNA splicing contributes to the regulation of alternative Splicing2009

    • Author(s)
      Fukumura, K
    • Journal Title

      Nucleic Acids Res Vol.37, No.6

      Pages: 1907-1914

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Isolation and characterization of postsplicing lariat-intron complexes2009

    • Author(s)
      Yoshimoto, R
    • Journal Title

      Nucleic Acids Res 37

      Pages: 891-902

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Immunoprecipitation analysis to study RNA-protein interactions in Xenopus oocytes2008

    • Author(s)
      Mabuchi, N., Masuyama, K. and Ohno, M
    • Journal Title

      Methods Mol. Biol

      Volume: 488 Pages: 257-65

    • DOI

      10.1007/978-1-60327-475-3_18

    • ISBN
      9781588294197, 9781603274753
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ATP- dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP562008

    • Author(s)
      Taniguchi,I. and Ohno,M
    • Journal Title

      Mol. Cell. Biol

      Volume: 28 Pages: 601-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A compartmentalized phosphorylation/ dephosphorylation system that regulates U snRNA export from the nucleu2008

    • Author(s)
      Kitao, S., Segref, A., Kast, J., Wilm, M., Mattaj, I, W. and Ohno, M
    • Journal Title

      Mol. Cell. Biol

      Volume: 28 Pages: 487-97

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP562008

    • Author(s)
      Taniguchi, I., Ohno, M.
    • Journal Title

      Mol.Cell.Biol. 28

      Pages: 601-608

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] A compartmentalized phosphorylation/ dephosphorylation system that regulates U snRNA export from the nucleu.2008

    • Author(s)
      Kitao, S., Segref, A., Kast, J., Wilm, M., Mattaj, I, W., Ohno, M.
    • Journal Title

      Mol.Cell.Biol. 28

      Pages: 487-497

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Immunoprecipitation analysis to study RNA-protein interactions in Xenopus oocytes2008

    • Author(s)
      Mabuchi, N
    • Journal Title

      Methods Mol.Biol 488

      Pages: 257-265

    • Related Report
      2008 Annual Research Report
  • [Presentation] 真核生物リボソームの品質管理2013

    • Author(s)
      北畠  真
    • Organizer
      第2回 RIBOSOME MEETING
    • Place of Presentation
      東京農工大学(府中市)
    • Year and Date
      2013-03-28
    • Related Report
      2012 Annual Research Report
  • [Presentation] Classical low-throughput analyses on RNA export from the nucleus2013

    • Author(s)
      Ohno,M
    • Organizer
      第2回 RNA and Biofunctions- ASIA Study
    • Place of Presentation
      Hotel Leopalace Hakata. Japan
    • Year and Date
      2013-01-10
    • Related Report
      2012 Final Research Report
  • [Presentation] Classical low-throughput analyses on RNA export from the nucleus2013

    • Author(s)
      Ohno, M
    • Organizer
      第2回 RNA and Biofunctions-ASIA Study
    • Place of Presentation
      ホテルレオパレス博多(福岡市)
    • Year and Date
      2013-01-10
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 真核生物リボソームの品質管理2012

    • Author(s)
      佐野 広大
    • Organizer
      平成24年度京都大学ウイルス研究所学術交流会
    • Place of Presentation
      京都大学iPS研究所CiRA講堂(京都市)
    • Year and Date
      2012-12-17
    • Related Report
      2012 Annual Research Report
  • [Presentation] hnRNP C tetramer regulates RNP formation at the cap-proximal region in mRNA export2012

    • Author(s)
      マクロースキ-亜紗子
    • Organizer
      第35回 日本分子生物学会
    • Place of Presentation
      福岡国際会議場 マリンメッセ福岡(福岡市)
    • Year and Date
      2012-12-11
    • Related Report
      2012 Annual Research Report
  • [Presentation] Nuclear RNA Binding Protein hnRNP C Measures the Length of RNA Polymerase II Transcripts and Sorts them into two RNA Categories for Nuclear Export2012

    • Author(s)
      Ohno, M
    • Organizer
      第19回東アジアシンポジウム
    • Place of Presentation
      Seoul National University (Seoul South Korea)
    • Year and Date
      2012-08-22
    • Related Report
      2012 Annual Research Report
  • [Presentation] RNAの仕分け・長いか短いか、正常か異常か2012

    • Author(s)
      大野 睦人
    • Organizer
      京都大学ウイルス研究所学術講演会
    • Place of Presentation
      芝蘭会館稲盛ホール(京都市)
    • Year and Date
      2012-07-26
    • Related Report
      2012 Annual Research Report
  • [Presentation] 真核生物リボソームの品質管理2012

    • Author(s)
      北畠 真
    • Organizer
      第14回日本RNA学会年会
    • Place of Presentation
      東北大学百周年記念会館 川内萩ホール(仙台市)
    • Year and Date
      2012-07-18
    • Related Report
      2012 Annual Research Report
  • [Presentation] hnRNP C四量体はキャップ近傍における輸送複合体形成を制御する2012

    • Author(s)
      マクロースキ-亜紗子
    • Organizer
      第14回日本RNA学会年会
    • Place of Presentation
      東北大学百周年記念会館 川内萩ホール(仙台市)
    • Year and Date
      2012-07-18
    • Related Report
      2012 Annual Research Report
  • [Presentation] 真核生物リボソームの品質管理に関わる新たな因子の探索2012

    • Author(s)
      佐野 広大
    • Organizer
      第14回日本RNA学会年会
    • Place of Presentation
      東北大学百周年記念会館 川内萩ホール(仙台市)
    • Year and Date
      2012-07-18
    • Related Report
      2012 Annual Research Report
  • [Presentation] 機能不全リボソームRNAの分解においてたんぱく質分解経路の果たす役割2012

    • Author(s)
      北畠 真
    • Organizer
      第12回 日本蛋白質科学会年会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2012-06-20
    • Related Report
      2012 Annual Research Report
  • [Presentation] 40S Subunit Dissociation and Proteasome-dependent RNA Degradation in Nonfunctional 25S rRNA Decay2012

    • Author(s)
      Kitabatake, M
    • Organizer
      The22nd CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology,(kobe)
    • Year and Date
      2012-06-11
    • Related Report
      2012 Annual Research Report
  • [Presentation] 40S Subunit Dissociation and Proteasome-dependent RNA Degradation in Nonfunctional 25S rRNA Decay2012

    • Author(s)
      Kitabatake, M
    • Organizer
      RNA 2012 Sixteenth Annual Meeting of the RNA Society
    • Place of Presentation
      University of Michigan (Detroit, USA)
    • Year and Date
      2012-05-29
    • Related Report
      2012 Annual Research Report
  • [Presentation] 真核生物リボソームの品質管理2012

    • Author(s)
      北畠真
    • Organizer
      第1回リボソームミーアィング
    • Place of Presentation
      広島大学(広島市)
    • Year and Date
      2012-03-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 機能不全rRNAの分解においてタンパク質分解経路の果たす役割2012

    • Author(s)
      藤井耕太郎
    • Organizer
      第1回リボソームミーアィング
    • Place of Presentation
      広島大学(広島市)
    • Year and Date
      2012-03-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 機能不全リボソームの分解に関わるE3ユビキチンリガーゼ複合体の解析2012

    • Author(s)
      坂田知子
    • Organizer
      第1回リボソームミーアィング
    • Place of Presentation
      広島大学(広島市)
    • Year and Date
      2012-03-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Nuclear RNA Binding Protein hnRNP C Measures the Length of RNA Polymerase II Transcripts and Sorts them into two RNA Categories for Nuclear Export2012

    • Author(s)
      Ohno,M
    • Organizer
      第19回東アジアシンポジウム
    • Place of Presentation
      Hoam Faculty House. Seoul. South Korea
    • Related Report
      2012 Final Research Report
  • [Presentation] 40S subunit dissociation and proteasome-dependent RNA degradation in nonfunctional 25S rRNA decay2012

    • Author(s)
      Kitabatake,M
    • Organizer
      The 22nd CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology. Kobe. Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] 40S subunit dissociation and proteasome-dependent RNA degradation in nonfunctional 25S rRNA decay2012

    • Author(s)
      Kitabatake,M
    • Organizer
      RNA 2012 Sixteenth Annual Meeting of the RNA Society
    • Place of Presentation
      University of Michigan. Detroit. USA
    • Related Report
      2012 Final Research Report
  • [Presentation] HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export2012

    • Author(s)
      McCloskey,A
    • Organizer
      The 10th International Student
    • Place of Presentation
      Shiran Kaikan, Inamori Hall. Kyoto. Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export2012

    • Author(s)
      McCloskey, A
    • Organizer
      The 10th International Student
    • Place of Presentation
      芝蘭会館(京都市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] U snRNA核外輸送を促進する因子の解析2011

    • Author(s)
      和泉光人
    • Organizer
      平成23年度京都大学ウイルス研究所学術交流会
    • Place of Presentation
      京都教育文化センター(京都市)
    • Year and Date
      2011-12-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] RNAの核外輸送や品質管理におけるRNA識別2011

    • Author(s)
      大野睦人
    • Organizer
      2nd Forum in DOJIN
    • Place of Presentation
      熊本ホテルキャッスル(熊本市)
    • Year and Date
      2011-11-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] A novel activity of HIV-1 Rev protein to remodel export RNPs in directing virus-specific RNA export. Cerevisiae2011

    • Author(s)
      Taniguchi,I
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      kyoto International Coference Cente. kyoto Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] In vivo reversal of a UV-induced lesion on mouse 28S rRNA2011

    • Author(s)
      Miyata,A
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      kyoto International Coference Cente. kyoto Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] HnRNPC1/C2 tetramer measures RNA length to ensure the proper nuclear export of messenger RNAs2011

    • Author(s)
      McCloskey,A
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      kyoto International Coference Cente. kyoto Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] Functional Decay of Nonfunctional 25S rRNA Requires Proteasome Activity2011

    • Author(s)
      Fujii,K
    • Organizer
      The 9th International Student Seminar.Kyoto
    • Place of Presentation
      Shiran Kaikan, Inamori Hall. kyoto Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] 真核生物におけるリボソームRNAの品質管理のメカニズム2011

    • Author(s)
      北畠真
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] A novel activity of HIV-1 Rev protein to remodel export RNPs in directing virus-specific RNA export2011

    • Author(s)
      Taniguchi, I
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] HnRNP Cの4量体はRNAの長さを測り、核外輸送へ向けてRNA polymerase II由来の転写産物を仕分けする2011

    • Author(s)
      マクロースキー亜紗子
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Nonfunctional rRNA decay functionally requires proteasome activity2011

    • Author(s)
      Fujii, K
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 機能不全リボソームを分解に関わるE3ユビキチンリガーゼ複合体の解析2011

    • Author(s)
      坂田知子
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Characterization of a degradation intermediate of the nonfunctional ribおsome2011

    • Author(s)
      Sakai, T
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] hnRNP Cの四量体は核外輸送に際してRNAの長さを測る2011

    • Author(s)
      大野睦人
    • Organizer
      第10回核ダイナミクス研究会
    • Place of Presentation
      クラッセホテル北広島(北広島市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス細胞内における28S rRNA上に生じた紫外線損傷の修復2011

    • Author(s)
      宮田淳美
    • Organizer
      RNAフロンティアミーティング2011
    • Place of Presentation
      あいち健康プラザ(大府市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] U snRNAの核外輸送を促進する因子の同定2011

    • Author(s)
      和泉光人
    • Organizer
      RNAフロンティアミーティング2011
    • Place of Presentation
      あいち健康プラザ(大府市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Unraveling the Molecular Mechanism of Nonfunctional 25S rRNA Decay : Proteasome-Dependent Step-wise Degradation of Mutant rRNAs in S.cerevisiae2011

    • Author(s)
      Kitabatake, M
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      Kyoto International Conference
    • Related Report
      2011 Annual Research Report
  • [Presentation] A novel activity of HIV-1 Rev protein to remodel export RNPs in directing virus-specific RNA export. Cerevisiae2011

    • Author(s)
      Taniguchi, I
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      Kyoto International Conference
    • Related Report
      2011 Annual Research Report
  • [Presentation] In vivo reversal of a UV-induced lesion on mouse 28S rRNA2011

    • Author(s)
      Miyata, A
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      Kyoto International Conference
    • Related Report
      2011 Annual Research Report
  • [Presentation] HnRNPC1/C2 tetramer measures RNA length to ensure the proper nuclear export of messenger RNAs2011

    • Author(s)
      McCloskey, A
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      Kyoto International Conference
    • Related Report
      2011 Annual Research Report
  • [Presentation] p54nrb and PSF promote Nuclear Export of Spliceosomal U snRNA precursors2011

    • Author(s)
      Izumi, H
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      Kyoto International Conference
    • Related Report
      2011 Annual Research Report
  • [Presentation] Identification of Scaffold Attachment Factor B1 (SAFB1) as a candidate factor that measures RNA length2011

    • Author(s)
      Nishio, H
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      Kyoto International Conference
    • Related Report
      2011 Annual Research Report
  • [Presentation] Xrn1 and the exosome are involved in nonfunctional 25S rRNA decay2011

    • Author(s)
      Sakai, T
    • Organizer
      2011 RNA meeting
    • Place of Presentation
      Kyoto International Conference
    • Related Report
      2011 Annual Research Report
  • [Presentation] Functional Decay of Nonfunctional 25S rRNA Requires Proteasome Activity2011

    • Author(s)
      Fujii, K
    • Organizer
      The 9th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] p54nrb and PSF promote Nuclear Export of U snRNAs2011

    • Author(s)
      Izumi, H
    • Organizer
      The 9th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都市)
    • Related Report
      2010 Annual Research Report
  • [Presentation] HnRNPC1/C2 4量体はRNA核外輸送の際にRNAの長さを測る2010

    • Author(s)
      マクロースキー亜紗子
    • Organizer
      平成22年度京都大学ウイルス研究所学術交流会
    • Place of Presentation
      京都教育文化センター(京都市)
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] HnRNPC1/C2 tetramer measures RNA length prior to RNA export from the nucleus2010

    • Author(s)
      McCloskey,A
    • Organizer
      15th annual Meeting of the RNA Society
    • Place of Presentation
      University of Washington. Seattle USA
    • Related Report
      2012 Final Research Report
  • [Presentation] A mechanism to measure RNA length prior to RNA export from the nucleus2010

    • Author(s)
      Ohno,M
    • Organizer
      19th CDB Meeting.May 10-12, 2010
    • Place of Presentation
      RIKEN Center for Developmental biology. kobe Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] Selective Degradation of Nonfunctional Ribosomal RNAs Mediated by the Ubiquitin-proteasome System2010

    • Author(s)
      Kitabatake,M
    • Organizer
      19th CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology. kobe Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] Analysis of cis- and trans- acting Elements for Nuclear Pre-mRNA Retention2010

    • Author(s)
      Takeiwa,T
    • Organizer
      The 8th International Student Seminar
    • Place of Presentation
      kyoto, Shiran Kaikan, Inamori Hall. kyoto Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] HnRNPC1/C2 tetramer measures RNA length prior to RNA export from the nucleus.2010

    • Author(s)
      McCloskey, A., Taniguchi, I., Ohno, M.
    • Organizer
      15th annual Meeting of the RNA Society.
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] A mechanism to measure RNA length prior to RNA export from the nucleus.2010

    • Author(s)
      Ohno, M.
    • Organizer
      19th CDB Meeting.
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 真核生物における機能不全リボソームの選択的分解2010

    • Author(s)
      北畠真
    • Organizer
      第33回日本分子生物学会
    • Place of Presentation
      ポートアイランド国際展示場2号館(神戸市)
    • Related Report
      2010 Annual Research Report
  • [Presentation] A Role for Ubiquitin in the Clearance of Nonfunctional Ribosomal RNAs2010

    • Author(s)
      Kitabatake, M
    • Organizer
      第39回環境変異原学会
    • Place of Presentation
      つくば国際会議場(つくば市)
    • Related Report
      2010 Annual Research Report
  • [Presentation] リボソームの品質管理における機能不全25S rRNAの分解2010

    • Author(s)
      酒井朗恵
    • Organizer
      RNAフロンティアミーティング2010
    • Place of Presentation
      富士教育研修所(裾野市)
    • Related Report
      2010 Annual Research Report
  • [Presentation] RNAの長さを測る因子の候補SAFB1の解析2010

    • Author(s)
      西尾治幾
    • Organizer
      RNAフロンティアミーティング2010
    • Place of Presentation
      富士教育研修所(裾野市)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Selective Degradation of nonfunctional ribosomal particles2010

    • Author(s)
      北畠真
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] RNA核外輸送におけるHIV-1タンパク質Revの新規機能2010

    • Author(s)
      谷口一郎
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] HnRNPC1/C2 4量体はRNA核外輸送の際にRNAの長さを測る2010

    • Author(s)
      マクロースキー亜紗子
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 翻訳阻害剤等によるリボソーム複合体のユビキチン化の解析2010

    • Author(s)
      坂田知子
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] U snRNAの核外輸送を促進する因子の同定2010

    • Author(s)
      和泉光人
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] リボソームの品質管理における機能不全25S rRNAの分解2010

    • Author(s)
      酒井朗恵
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cis-acting RNA Elements and Trans-acting Factors for Nuclear Pre-mRNA Retention2010

    • Author(s)
      Takeiwa, T
    • Organizer
      The 17th East Asia Joint Symposium
    • Place of Presentation
      Gis National Taiwan University Convention Center (Taipei, Taiwan)
    • Related Report
      2010 Annual Research Report
  • [Presentation] A role of Cajal bodies for surveillance of export U snRNP assembly2010

    • Author(s)
      Ohno, M
    • Organizer
      2010 RNA meeting
    • Place of Presentation
      University of Washington (Seattle, USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Biochemical Purification and Characterization of Nonfunctional Mutant Ribosomes2010

    • Author(s)
      Kitabatake, M
    • Organizer
      2010 RNA meeting
    • Place of Presentation
      University of Washington (Seattle, USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] HnRNPC1/C2 tetramer measures RNA length prior to RNA export from the nucleus2010

    • Author(s)
      McCloskey, A
    • Organizer
      2010 RNA meeting
    • Place of Presentation
      University of Washington (Seattle, USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Multistep RNA Degradation Mechanism in Nonfunctional 25S rRNA Decay2010

    • Author(s)
      Fujii, K
    • Organizer
      2010 RNA meeting
    • Place of Presentation
      University of Washington (Seattle, USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Distinct ubiquitinations of ribosomal particles caused by translation elongation inhibitors2010

    • Author(s)
      Sakata, T
    • Organizer
      2010 RNA meeting
    • Place of Presentation
      University of Washington (Seattle, USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] A mechanism to measure RNA length prior to RNA export from the nucleus2010

    • Author(s)
      Ohno, M
    • Organizer
      19th CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology (kobe, Japan)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Selective Degradation of Nonfunctional Ribosomal RNAs Mediated by the Ubiquitin-proteasome System2010

    • Author(s)
      Kitabatake, M
    • Organizer
      19th CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology (kobe, Japan)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional Decay of Nonfunctional 25S rRNA Requires Proteasome Activity2010

    • Author(s)
      Fujii, K
    • Organizer
      19th CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology (kobe, Japan)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cis-acting RNA Elements and Trans-acting Factors for Nuclear Pre-mRNA Retention2010

    • Author(s)
      Takeiwa, T
    • Organizer
      19th CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology (kobe, Japan)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Identification of a Candidate Factor that promotes Nuclear Export of U snRNAs2010

    • Author(s)
      Izumi, H
    • Organizer
      19th CDB Meeting
    • Place of Presentation
      RIKEN Center for Developmental biology (kobe, Japan)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional Decay of Nonfunctional 25S rRNA Requires Proteasome Activity2010

    • Author(s)
      Fujii, K
    • Organizer
      The 8th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Analysis of cis- and trans- acting Elements for Nuclear Pre-mRNA Retention2010

    • Author(s)
      Takeiwa, T
    • Organizer
      The 8th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identification of a Candidate Factor that promotes Nuclear Export of U snRNAs2010

    • Author(s)
      Izumi, H
    • Organizer
      The 8th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] U snRNA核外輸送におけるPHAXの新しい機能2009

    • Author(s)
      鈴木達也
    • Organizer
      第6回 京都大学ウイルス研究所学術交流会
    • Place of Presentation
      京大会館(京都市)
    • Year and Date
      2009-12-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Isolation and characterization of post-splicing lariat-intron complexes2009

    • Author(s)
      Yoshimoto, R
    • Organizer
      The 7th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都市)
    • Year and Date
      2009-03-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Selective degradation of non-functional ribosomal protein in S.cerevisiae2009

    • Author(s)
      Sakata, T
    • Organizer
      The 7th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都市)
    • Year and Date
      2009-03-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Searching for RNA Elements for Nuclear Pre-mRNA Retention2009

    • Author(s)
      Takeiwa, T
    • Organizer
      The 7th International Student Seminar
    • Place of Presentation
      芝蘭会館(京都市)
    • Year and Date
      2009-03-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Functional Decay of Nonfunctional 25S rRNA Requires Proteasome Activity2009

    • Author(s)
      Fujii,K
    • Organizer
      The 16th East Asia Joint Conference on Biomedical Research
    • Place of Presentation
      Shiran Kaikai. Kyoto Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] A role for ubiquitin in the clearance of nonfunctional rRNAs2009

    • Author(s)
      Kitabatake,M
    • Organizer
      14th annual Meeting of the RNA Society
    • Place of Presentation
      University of Wisconsin campus. USA
    • Related Report
      2012 Final Research Report
  • [Presentation] A role for ubiquitin in the clearance of nonfunctional rRNAs.2009

    • Author(s)
      Kitabatake, M., Fujii, K., Sakata, T., Ohno, M.
    • Organizer
      14th annual Meeting of the RNA Society.
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 核外輸送においてmRNAとUsnRNAを識別する機構2009

    • Author(s)
      マクロースキー亜紗子
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] HeLa細胞におけるmRNA前駆体核内保持因子の探索2009

    • Author(s)
      竹村玲子
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 機能不全rRNAの品質管理機構~ユビキチン-プロテアソーム系の関わり2009

    • Author(s)
      藤井耕太郎
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] リボソ-ムRNAの品質管理におけるユビキチンの新たな役割2009

    • Author(s)
      北畠真
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] mRNA前駆体の核内保持に必要なシス配列の探索2009

    • Author(s)
      竹岩俊彦
    • Organizer
      RNAフロンティアミーティング2009
    • Place of Presentation
      IPC生産性国際交流センター(神奈川県三浦郡)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional Decay of Nonfunctional 25S rRNA Requires Proteasome Activity2009

    • Author(s)
      Fujii, K
    • Organizer
      The 16th East Asia Joint Conference on Biomedical Research
    • Place of Presentation
      芝蘭会館(京都市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] A role for ubiquitin in the clearance of nonfunctional rRNAs2009

    • Author(s)
      Kitabatake, M
    • Organizer
      Ribosome Synthesis Meeting
    • Place of Presentation
      Kolpinghaus (Germany)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Selective degradation of nonfunctional ribosomal protein in S.cerevisiae2009

    • Author(s)
      Sakata, T
    • Organizer
      Ribosome Synthesis Meeting
    • Place of Presentation
      Kolpinghaus (Germany)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional association of the Microprocessor complex with spliceosome2009

    • Author(s)
      Kataoka, N
    • Organizer
      Eukaryotic mRNA processing
    • Place of Presentation
      Cold Spring Harbor (USA)
    • Related Report
      2009 Annual Research Report
  • [Presentation] A role for ubiquitin in the clearance of nonfunctional rRNAs2009

    • Author(s)
      Kitabatake, M
    • Organizer
      Fourteenth annual Meeting of the RNA Society 2009
    • Place of Presentation
      ウイスコンシン大学マディソン校(USA)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional Decay of Nonfunctional 25S rRNA Requires Proteasome Activity2009

    • Author(s)
      Fujii, K
    • Organizer
      Fourteenth annual Meeting of the RNA Society 2009
    • Place of Presentation
      ウイスコンシン大学マディソン校(USA)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 機能不全リボソームの品質管理におけるユビキチンの新機能2008

    • Author(s)
      藤井耕太郎
    • Organizer
      第7回 京都大学ウイルス研究所学術交流会
    • Place of Presentation
      京大会館(京都市)
    • Year and Date
      2008-12-22
    • Related Report
      2008 Annual Research Report
  • [Presentation] Role of purine-rich exonic splicing enhancers in nuclear retention of pre-mRNAs2008

    • Author(s)
      谷口一郎
    • Organizer
      第21回 内藤コンファレンス
    • Place of Presentation
      大泉高原八ヶ岳ロイヤルホテル(山梨県北杜市)
    • Year and Date
      2008-06-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Regulations of nucleo- cytoplasmic RNA distribution2008

    • Author(s)
      Ohno,M
    • Organizer
      NAIST Global COE Symposium on Cell Signaling
    • Place of Presentation
      Nara Institute of Science and Technology. Nara Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] Regulations of nucleocytoplasmic RNA distribution.2008

    • Author(s)
      Ohno, M.
    • Organizer
      NAIST Global COE Symposium on Cell Signaling.
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Nuclear Retention Mechanisms for Pre-mRNAs2008

    • Author(s)
      大野睦人
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] RNA核外輸送におけるHIV-1タンパク質Revの新規機能2008

    • Author(s)
      谷口一郎
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 核外輸送においてUsnRNAとmRNAを識別する機構2008

    • Author(s)
      マクロースキー亜沙子
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] HeLa細胞におけるmRNA前駆体核内係留因子の探索2008

    • Author(s)
      竹村玲子
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 出芽酵母における機能不全リボソーム蛋白質の選択的分解2008

    • Author(s)
      坂田知子
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] mRNA前駆体の核内繋留に必要なシス配列の探索2008

    • Author(s)
      竹岩俊彦
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Regulations of nucleo-cytoplasmic RNA distribution2008

    • Author(s)
      Ohno, M
    • Organizer
      NAIST Global COE Symposium on Cell Signaling
    • Place of Presentation
      奈良先端科学技術大学(奈良市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] RNAの細胞内分配制御2008

    • Author(s)
      大野睦人
    • Organizer
      蛋白質研究所セミナー
    • Place of Presentation
      大阪大学蛋白質研究所(大阪市)
    • Related Report
      2008 Annual Research Report
  • [Presentation] U snRNA核外輸送におけるPHAXの新しい機能2008

    • Author(s)
      鈴木達也
    • Organizer
      第10回日本RNA学会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2018-03-28  

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