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Structural and functional studies for nuclear macromolecular complexes

Planned Research

Project AreaThe physicochemical field for genetic activities
Project/Area Number 20114005
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionWaseda University

Principal Investigator

KURUMIZAKA Hitoshi  早稲田大学, 理工学術院, 教授 (80300870)

Project Period (FY) 2008 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥143,260,000 (Direct Cost: ¥110,200,000、Indirect Cost: ¥33,060,000)
Fiscal Year 2012: ¥21,060,000 (Direct Cost: ¥16,200,000、Indirect Cost: ¥4,860,000)
Fiscal Year 2011: ¥21,970,000 (Direct Cost: ¥16,900,000、Indirect Cost: ¥5,070,000)
Fiscal Year 2010: ¥21,060,000 (Direct Cost: ¥16,200,000、Indirect Cost: ¥4,860,000)
Fiscal Year 2009: ¥23,140,000 (Direct Cost: ¥17,800,000、Indirect Cost: ¥5,340,000)
Fiscal Year 2008: ¥56,030,000 (Direct Cost: ¥43,100,000、Indirect Cost: ¥12,930,000)
Keywords染色体 / 遺伝子 / 蛋白質 / 高次構造 / 細胞核 / 染色体構築・機能・分配 / 遺伝情報複製・再編 / ゲノム多様性 / ゲノム進化・再編 / ゲノム機能 / 活性発現の分子機構 / 生体高分子構造・機能 / 構造活性相関 / ゲノム再編・発現・維持 / 遺伝子及び染色体 / タンパク質と酵素 / 生体分子立体構造解析及び予測 / 構造生物学 / X線結晶解析 / ヒストン / ヌクレオソーム / クロマチン / エピジェネティクス
Research Abstract

Nucleosome is the primary building block for chromatin, which packages huge genomic DNA. Histones are protein components of the nucleosome, and several non-allelic histone variants have been identified in higher eukaryotes. In this study, we determined the crystal structures of human nucleosomes, containing one of each histone H3 variants, H3.1, H3.2, H3.3, H3T, or CENP-A. We also identified novel histone variants, which promote nucleosome assembly. These findings provide important information to understand the chromatin architecture with functional nucleosome dynamics.

Report

(7 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (201 results)

All 2013 2012 2011 2010 2009 2008

All Journal Article (71 results) (of which Peer Reviewed: 71 results) Presentation (125 results) (of which Invited: 2 results) Book (5 results)

  • [Journal Article] Vertebrate Spt2 is a novel nucleolar histone chaperone that assists in ribosomal DNA transcription2013

    • Author(s)
      Osakabe A., Tachiwana H., Takaku M., Hori T., Obuse C., Kimura H., Fukagawa T., Kurumizaka H
    • Journal Title

      J. Cell Sci

      Volume: 126 Pages: 1323-1332

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Purification and characterization of the fission yeast telomere clustering factors, Bqt1 and Bqt22013

    • Author(s)
      Ichikawa Y., Kagawa W., Saito K., Chikashige Y., Haraguchi T., Hiraoka Y., Kurumizaka H
    • Journal Title

      Prot. Exp. Purif

      Volume: 88 Pages: 207-213

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gas-Phase Structure of the Histone Multimers Characterized by Ion Mobility Mass Spectrometry and Molecular Dynamics Simulation2013

    • Author(s)
      Saikusa K., Fuchigami S., Takahashi K., Asano Y., Nagadoi A., Tachiwana H., Kurumizaka H., Ikeguchi M., Nishimura Y., Akashi, S
    • Journal Title

      Anal. Chem

      Volume: 85 Pages: 4165-4171

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Current progress on structural studies of nucleosomes containing histone H3 variants2013

    • Author(s)
      Kurumizaka H., Horikoshi N., Tachiwana H., Kagawa W
    • Journal Title

      Curr. Opin. Struct. Biol

      Volume: 23 Pages: 109-115

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nap1 regulates proper CENP-B binding to nucleosomes2013

    • Author(s)
      Tachiwana H., Miya Y., Shono N., Ohzeki J., Osakabe A., Otake K., Larionov V., Earnshaw W.C., Kimura H., Masumoto H., Kurumizaka H
    • Journal Title

      Nucleic Acids Res

      Volume: 5 Pages: 2869-2880

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Purification and characterization of the fission yeast telomere clustering factors, Bqt1 and Bqt22013

    • Author(s)
      Ichikawa Y, Kagawa W, Saito K, C hikashige Y, Haraguchi T, Hiraoka Y , Kurumizaka H.
    • Journal Title

      Protein Expr Puff.

      Volume: 88 Issue: 2 Pages: 207-213

    • DOI

      10.1016/j.pep.2013.01.006

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nap1 regulates proper CENP-B binding to nucleosomes2013

    • Author(s)
      Tachiwana H, Miya Y, Shono N, Ohzeki J, Osakabe A, Otake K, Larionov V, Earnshaw WC, Kimura H, Masumoto H, Kurumizaka H
    • Journal Title

      Nucleic Acids Res

      Volume: 5 Issue: 5 Pages: 2869-2880

    • DOI

      10.1093/nar/gks1464

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair2012

    • Author(s)
      Sato K., Ishiai M., Toda K., Furukoshi S., Osakabe A., Tachiwana H., Takizawa Y., Kagawa W., Kitao H., Dohmae N., Obuse C., Kimura H., Takata M., Kurumizaka H
    • Journal Title

      EMBO J

      Volume: 31 Pages: 3524-3536

    • NAID

      120005243432

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chd2 interacts with H3.3 to determine myogenic cell fate2012

    • Author(s)
      Harada A., Okada S., Odawara J Kumamaru H., Saiwai H., Konno D., Yoshimi T., Yoshimura S., Tachibana T., Tsubota T., Kurumizaka H., Akashi K., Imbalzano A.N., Ohkawa Y
    • Journal Title

      EMBO J

      Volume: 31 Pages: 2994-3007

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural analysis of the hexasome, lacking one histone H2A/H2B dimer from the conventional nucleosome2012

    • Author(s)
      Arimura Y., Tachiwana H., Oda T., Sato M., Kurumizaka H
    • Journal Title

      Biochemistry

      Volume: 51 Pages: 3302-3309

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison between the CENP-A and histone H3 structures in nucleosomes2012

    • Author(s)
      Tachiwana H., Kagawa W., Kurumizaka H
    • Journal Title

      Nucleus

      Volume: 3 Pages: 1-6

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Current progress on structural studies of nucleosomes containing histone H3 variants2012

    • Author(s)
      Hitoshi Kurumizaka, Naoki Horikoshi, Hiroaki Tachiwana, Wataru Kagawa.
    • Journal Title

      Current Opinion Structural Biology

      Volume: 23 Issue: 1 Pages: 109-115

    • DOI

      10.1016/j.sbi.2012.10.009

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair2012

    • Author(s)
      Koichi Sato. Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka
    • Journal Title

      The EMBO Journal

      Volume: 31 Issue: 17 Pages: 3524-3536

    • DOI

      10.1038/emboj.2012.197

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chd2 interacts with H3.3 to determine myogenic cell fate2012

    • Author(s)
      Harada A, Okada S, Konno D, Odawara J, Yoshimi T, Yoshimura S, Kumamaru H, Saiwai H, Tsubota T, Kurumizaka H, Akashi K, Tachibana T, Imbalzano AN, Ohkawa Y
    • Journal Title

      EMBO J

      Volume: 31 Issue: 13 Pages: 2994-3007

    • DOI

      10.1038/emboj.2012.136

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural Analysis of the Hexasome, Lacking One Histone H2A/H2B Dimer from the Conventional Nucleosome2012

    • Author(s)
      Y.Arimura, H.Tachiwana, T.Oda, M.Sato, H.Kurumizaka
    • Journal Title

      Biochem

      Volume: 51 Issue: 15 Pages: 3302-3309

    • DOI

      10.1021/bi300129b

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural basis for the DNA binding activity of the bacterial β-propeller protein YncE2011

    • Author(s)
      Kagawa W., Sagawa T., Niki H., Kurumizaka H
    • Journal Title

      Acta Cryst

      Volume: D67 Pages: 1045-1053

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comprehensive structural analysis of mutant nucleosomes containing lysine to glutamine (KQ) substitutions in the H3 and H4 histone-fold domains2011

    • Author(s)
      Iwasaki W., Tachiwana H., Kawaguchi K., Shibata T., Kagawa W., Kurumizaka H
    • Journal Title

      Biochemistry

      Volume: 50 Pages: 7822-7832

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystal structure of the human centromeric nucleosome containing CENP-A2011

    • Author(s)
      Tachiwana H., Kagawa W., Shiga T., Osakabe A., Miya Y., Saito K., Hayashi-Takanaka Y., Oda T., Sato M., Park S.-Y., Kimura H., Kurumizaka H
    • Journal Title

      Nature

      Volume: 476 Pages: 232-235

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structures of human nucleosomes containing major histone H3 variants2011

    • Author(s)
      Tachiwana H., Osakabe A., Shiga T., Miya Y., Kimura H., Kagawa W., Kurumizaka H
    • Journal Title

      Acta Cryst

      Volume: D67 Pages: 578-583

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling2011

    • Author(s)
      Hayashi-Takanaka Y., Yamagata K., Wakayama T., Stasevich T.J., Kainuma T., Tsurimoto T., Tachibana M., Shinkai Y., Kurumizaka H., Nozaki N., Kimura H
    • Journal Title

      Nucleic Acids Res

      Volume: 39 Pages: 6475-6488

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene2011

    • Author(s)
      Horikoshi N., Tachiwana H., Saito K., Osakabe A., Sato M., Yamada M., Akashi S., Nishimura Y., Kagawa W., Kurumizaka H
    • Journal Title

      Acta Cryst

      Volume: D67 Pages: 112-118

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural basis for the DNA binding activity of the bacterial β-propeller protein YncE2011

    • Author(s)
      Kagawa, W., Sagawa, T., Niki, H., Kurumizaka, H.
    • Journal Title

      Acta Cryst., D

      Volume: D67 Issue: 12 Pages: 1045-1053

    • DOI

      10.1107/s0907444911045033

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structures of human nucleosomes containing major histone H3 variants2011

    • Author(s)
      Tachiwana H, Osakabe A, Shiga T, Miya Y, Kimura H, Kagawa W, Kurnmizaka H
    • Journal Title

      Acta Crystallogr.D Biol.Crystallogr.

      Volume: 67 Issue: 6 Pages: 578-583

    • DOI

      10.1107/s0907444911014818

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene2011

    • Author(s)
      Naoki Horikoshi, et al.
    • Journal Title

      Acta Cryst.D

      Volume: 67 Pages: 112-118

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T2010

    • Author(s)
      Tachiwana H., Kagawa W., Osakabe A., Kawaguchi K., Shiga T., Hayashi-Takanaka, Y, Kimura, H., and Kurumizaka H
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 107 Pages: 10454-10459

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Deimination stabilizes histone H2A/H2B dimers as revealed by electrospray ionization mass spectrometry2010

    • Author(s)
      Shimoyama S., Nagadoi A., Tachiwana H., Yamada M., Sato M., Kurumizaka H., Nishimura Y., Akashi S
    • Journal Title

      J. Mass Spectrom

      Volume: 45 Pages: 900-908

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nucleosome formation activity of human sNASP2010

    • Author(s)
      Osakabe A., Tachiwana H., Matsunaga T., Shiga T., Nozawa R., Obuse C., Kurumizaka H
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 11913-11921

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase.2010

    • Author(s)
      Takaku, M., Takahashi, D., Machida, S., Ueno, H., Hosoya, N., Ikawa, S., Miyagawa, K., Shibata, T., Kurumizaka, H.
    • Journal Title

      Nucleic Acids Res. 38

      Pages: 7579-7586

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T.2010

    • Author(s)
      Tachiwana, H., Kagawa, W., Osakabe, A., Kawaguchi, K., Shiga, T., Hayashi-Takanaka, Y., Kimura, H., Kurumizaka, H.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 107

      Pages: 10454-10459

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Nucleosome formation activity of human sNASP.2010

    • Author(s)
      Osakabe, A., Tachiwana, H., Matsunaga, T., Shiga, T., Nozawa, R., Obuse, C., Kurumizaka, H.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 11913-11921

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents2010

    • Author(s)
      Kazunori Yoshikiyo, et al.
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: 107 Pages: 21553-21557

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T2010

    • Author(s)
      Hiroaki Tachiwana, et al.
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: 107 Pages: 10454-10459

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deimination stabilizes histone H2A/H2B dimers as revealed by electrospray ionization mass spectrometry2010

    • Author(s)
      Shingo Shimoyama, et al.
    • Journal Title

      J.Mass Spectrom.

      Volume: 45 Pages: 900-908

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nucleosome formation activity of human sNASP2010

    • Author(s)
      Akihisa Osakabe, et al.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 11913-11921

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase2010

    • Author(s)
      Motoki Takaku, et al.
    • Journal Title

      Nucleic Acids Res.

      Volume: 38 Pages: 7579-7586

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination2010

    • Author(s)
      Yoshimasa Takizawa, et al.
    • Journal Title

      Nucleic Acids Res.

      Volume: 38 Pages: 5059-5074

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site2010

    • Author(s)
      Kengo Saito, et al.
    • Journal Title

      J.Biochem.

      Volume: 147 Pages: 833-842

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Holliday junction binding activity of human SPF452010

    • Author(s)
      Naoki Horikoshi, et al.
    • Journal Title

      Genes Cells

      Volume: 5 Pages: 373-383

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 発がん防御に重要な相同組換えの分子機構2010

    • Author(s)
      齋藤健吾, 他
    • Journal Title

      最新医学

      Volume: 65 Pages: 1318-1330

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] From meiosis to postmeiotic events : Uncovering the molecular roles of the meiosis-specific recombinase Dmci.2010

    • Author(s)
      Kagawa, W., Kurumizaka, H.
    • Journal Title

      FEBS J. 277

      Pages: 590-598

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamics in the transmission of genetic information : from meiosis to postmeiotic events.2010

    • Author(s)
      Kagawa, W., Kurumizaka, H.
    • Journal Title

      FEBS J. 277

      Pages: 564-564

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical analysis of the human EVL domains in homologous recombination2009

    • Author(s)
      Takaku M., Machida S., Nakayama S., Takahashi D., Kurumizaka H
    • Journal Title

      FEBS J

      Volume: 276 Pages: 5841-5848

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities2009

    • Author(s)
      Morozumi Y., Takizawa Y., Takaku M., Kurumizaka H
    • Journal Title

      Nucleic Acids Res

      Volume: 37 Pages: 4296-4307

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction2009

    • Author(s)
      Katsura M., Tsuruga T., Date O., Yoshihara T., Ishida M., Tomoda Y., Okajima M., Takaku M., Kurumizaka H., Kinomura A., Mishima H., Miyagawa K
    • Journal Title

      Nucleic Acids Res

      Volume: 37 Pages: 3959-3968

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recombination activator function of the novel RAD51- and RAD51B-binding protein, Human EVL2009

    • Author(s)
      Takaku M., Machida S., Hosoya N., Nakayama S., Takizawa Y., Sakane I., Shibata T., Miyagawa K., Kurumizaka H
    • Journal Title

      J. Biol. Chem

      Volume: 284 Pages: 14326-14336

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange2009

    • Author(s)
      Ishida T., Takizawa Y., Kainuma T., Inoue J., Mikawa T., Shibata T., Suzuki H., Tashiro S., Kurumizaka H
    • Journal Title

      Nucleic Acids Res

      Volume: 37 Pages: 3367-3376

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] c-ABL tyrosine kinase stabilizes RAD51 chromatin association2009

    • Author(s)
      Shimizu H., Popova M., Fleury F., Kobayashi M., Hayashi N., Sakane I., Kurumizaka H., Venkitaraman A.R., Takahashi M., Yamamoto KI
    • Journal Title

      Biochem. Biophys Res. Commun

      Volume: 382 Pages: 286-291

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical analysis of the human DMC1-I37N polymorphism2009

    • Author(s)
      Hikiba J., Takizawa Y., Ikawa S., Shibata T., Kurumizaka H
    • Journal Title

      FEBS J

      Volume: 276 Pages: 457-465

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities.2009

    • Author(s)
      Morozumi, Y., Takizawa, Y., Takaku, M., Kurumizaka, H.
    • Journal Title

      Nucleic Acids Res. 37

      Pages: 4296-4307

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Recombination activator function of the novel RAD51- and RAD51B-binding protein, Human EVL.2009

    • Author(s)
      Takaku, M., Machida, S., Hosoya, N., Nakayama, S., Takizawa, Y., Sakane, I., Shibata, T., Miyagawa, K., Kurumizaka, H.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 14326-14336

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] c-ABL tyrosine kinase stabilizes RAD51 chromatin association.2009

    • Author(s)
      Shimizu, H., et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 382

      Pages: 286-291

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange.2009

    • Author(s)
      Ishida, T., et al.
    • Journal Title

      Nucleic Acids Res. 37

      Pages: 3361-3376

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recambination activator function of the novel RAD51- and RAD51B-binding protein, Human EVL.2009

    • Author(s)
      Takaku, M., et al.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 14326-14336

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction.2009

    • Author(s)
      Katsura, M., et al.
    • Journal Title

      Nucleic Acids Res. 37

      Pages: 3959-3968

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities.2009

    • Author(s)
      Morozumi, Y., et al.
    • Journal Title

      Nucleic Acids Res. 37

      Pages: 4296-4307

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical analysis of the human EVL domains in homologous recombination.2009

    • Author(s)
      Takaku, M., et al.
    • Journal Title

      FEBS J. 276

      Pages: 5841-5848

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical analysis of the human DMC1-137N polymorphism.2009

    • Author(s)
      Hikiba, J., Takizawa, Y., Ikawa, S., Shibata. T. and Kurumizaka, H
    • Journal Title

      FEBS J. 276

      Pages: 457-465

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural analysis of the human Rad51 protein-DNA complex filament by tryptophan fluorescence scanning analysis: transmission of allosteric effects between ATP binding and DNA binding2008

    • Author(s)
      Renodon-Corniere A. Takizawa Y., Conilleau1 S., Tran V., Iwai S., Kurumizaka H., Takahashi M
    • Journal Title

      J. Mol. Biol

      Volume: 383 Pages: 575-578

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical analysis of the N-terminal domain of human RAD54B2008

    • Author(s)
      Sarai N., Kagawa W., Fujikawa N., Saito K., Hikiba J., Tanaka K., Miyagawa K., Kurumizaka H., Yokoayama S
    • Journal Title

      Nucleic Acids Res

      Volume: 36 Pages: 5441-5450

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification of a second DNA binding site in the human Rad52 protein2008

    • Author(s)
      Kagawa W., Kagawa A., Saito K., Ikawa S., Shibata T., Kurumizaka H., Yokoyama S
    • Journal Title

      J. Biol. Chem

      Volume: 283 Pages: 24264-24273

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins2008

    • Author(s)
      Sakane I., Kamataki C., Takizawa Y., Nakashima M., Toki S., Ichikawa H., Ikawa S., Shibata T., Kurumizaka H
    • Journal Title

      Nucleic Acids Res

      Volume: 36 Pages: 4266-4276

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural and functional analyses of the DMC1-M200V polymorphism found in the human population2008

    • Author(s)
      Hikiba J., Hirota K., Kagawa W., Ikawa S., Kinebuchi T., Sakane I., Takizawa Y., Yokoyama S., Mandon-Pepin B., Nicolas A., Shibata T., Ohta K., Kurumizaka H
    • Journal Title

      Nucleic Acids Res

      Volume: 36 Pages: 4181-4190

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC-motif of the BRCA2 protein2008

    • Author(s)
      Nomme J., Takizawa Y., Martinez S., Renodon-Corniere A., Fleury F., Weigel P., Yamamoto K., Kurumizaka H., Takahashi M
    • Journal Title

      Genes Cells

      Volume: 13 Pages: 471-481

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro2008

    • Author(s)
      Tachiwana H., Osakabe A., Kimura H., Kurumizaka H
    • Journal Title

      Nucleic Acids Res

      Volume: 36 Pages: 2208-2218

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural analysis of the human Rad51 protein-DNA complex filament by tryptophan fluorescence scanning analysis : transmission of allosteric effects between ATP binding and DNA binding.2008

    • Author(s)
      Renodon-Corniere, A., et al.
    • Journal Title

      J. Mol. Biol. 383

      Pages: 575-578

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical analysis of the N-terminal domain of human RAD54B.2008

    • Author(s)
      Sarai, N., et al.
    • Journal Title

      Nucleic Acids Res. 36

      Pages: 5441-5450

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of a second DNA binding site in the human Rad52 protein2008

    • Author(s)
      Kagawa, W., et al.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 24264-24273

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins.2008

    • Author(s)
      Sakane, et al.
    • Journal Title

      Nucleic Acids Res. 36

      Pages: 4266-4276

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural and functional analyses of the DMC1-M200V polymorphism found in the human population.2008

    • Author(s)
      Hikiba, et al.
    • Journal Title

      Nucleic Acids Res. 36

      Pages: 4181-4190

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC-motif of the BRCA2 protein.2008

    • Author(s)
      Nome, J., et al.
    • Journal Title

      Genes Cells 13

      Pages: 471-481

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly pr oteins in vitro.2008

    • Author(s)
      Tachiwana, H., et al.
    • Journal Title

      Nucleic Acids Res. 36

      Pages: 2208-2218

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 動的なヌクレオソーム構造によるクロマチン制御機構2013

    • Author(s)
      胡桃坂仁志
    • Organizer
      第4回中性子小角散乱解析法研究会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] ヒストンバリアントによるヌクレオソームの構造多様性2013

    • Author(s)
      胡桃坂仁志
    • Organizer
      第1回ヒストンバリアント研究会
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Nucleosome structures during transcription and DNA repair2012

    • Author(s)
      Kurumizaka H.
    • Organizer
      The 8th 3R Symposium
    • Place of Presentation
      Awaji, Hyogo
    • Year and Date
      2012-11-25
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Structural basis for the functional versatility of human nucleosomes containing histone variants2012

    • Author(s)
      Kurumizaka H.
    • Organizer
      Telluride Workshop on Chromatin Structure and Dynamics
    • Place of Presentation
      Telluride, CO
    • Year and Date
      2012-08-06
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] セントロメアに特異的なCENP-T-W-S-Xヒストンフォールド複合体は正のスーパーコイルを導入する活性を持つ2012

    • Author(s)
      竹内康造, 西野達哉, 堀哲也, 立和名博昭, 越阪部晃永, 他
    • Organizer
      第29回染色体ワークショプ
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヘキサソームおよびH2A.Bbdを含むヌクレオソームの構造生物学的解析2012

    • Author(s)
      有村泰宏, 立和名博昭, 小田隆, 佐藤衛, 胡桃坂仁志
    • Organizer
      第29回染色体ワークショプ
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒトH2A.Z-1、H2A.Z-2を含むヌクレオソームの生化学的および構造生物学的解析2012

    • Author(s)
      堀越直樹, 立和名博昭, 香川亘, 越阪部晃永, …, 胡桃坂仁志
    • Organizer
      第29回染色体ワークショプ
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] 出芽酵母ミニ染色体におけるヌクレオソームの形成にヒトテロメア配列が及ぼす影響2012

    • Author(s)
      市川雄一, 諸橋伸行, 西村善文, 胡桃坂仁志, 清水光弘
    • Organizer
      第29回染色体ワークショプ
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] クロマチンでの相同組換えにおけるヒストンバリアント及びリンカーヒストンの影響2012

    • Author(s)
      町田晋一, 高久誉大, 小林航, 江川史郎, 江崎淳朗, …, 胡桃坂仁志
    • Organizer
      第29回染色体ワークショプ
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] クロマチン構造変換と細胞核機能におけるアクチンファミリーの寄与2012

    • Author(s)
      尾間由佳子, 中山景樹, 小西辰紀, 胡桃坂仁志, 原田昌彦
    • Organizer
      第29回染色体ワークショプ
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] CENP-Aヌクレオソームの高次クロマチン構造形成における影響2012

    • Author(s)
      立和名博昭, 堀越直樹, 松本亮平, 宮優太, 小田隆, …, 胡桃坂仁志
    • Organizer
      第29回染色体ワークショプ
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒストンとヒストンシャペロンによるクロマチンダイナミクス機構2012

    • Author(s)
      胡桃坂仁志
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] エピゲノムを担う機能的クロマチンにおけるヒストンバリアントの構造的役割2012

    • Author(s)
      胡桃坂仁志
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Nucleosome structures during transcription and DNA repair2012

    • Author(s)
      Kurumizaka H
    • Organizer
      The 8th 3R Symposium
    • Place of Presentation
      兵庫
    • Related Report
      2012 Final Research Report
  • [Presentation] Structural basis for the functional versatility of human nucleosomes containing histone variants2012

    • Author(s)
      Kurumizaka H
    • Organizer
      Telluride Workshop on Chromatin Structure and Dynamics
    • Place of Presentation
      Telluride、USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Structural basis for formation of functional chromatin architecture2011

    • Author(s)
      胡桃坂仁志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜(招待講演)
    • Year and Date
      2011-12-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] The Cdt1-binding protein GRWD1 is a novel histone chaperone involved in replication licensing2011

    • Author(s)
      杉本のぞみ, 安河内周平, 渡邉心也, 清野透, 胡桃坂仁志, 藤田雅俊
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Crystal structure and biochemical property of the human centromere specific nucleosome2011

    • Author(s)
      立和名博昭, 香川亘, 志賀達也, 松本亮平, …, 胡桃坂仁志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Reconstitution and biochemical analyses of the centromere specific chromatin2011

    • Author(s)
      松本亮平, 立和名博昭, 竹田瑶弥, 胡桃坂仁志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Biochemical analyses of the formation of the centromere-specific CENP-A nucleosome bound to the CENP-B DNA-binding domain2011

    • Author(s)
      宮優太, 立和名博昭, 越坂部晃永, 胡桃坂仁志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Histone chaperone activity of a novel histone interacting factor SPT22011

    • Author(s)
      越阪部晃永, 立和名博昭, 高久誉大, 堀哲也, 小布施力史, 木村宏, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Promotion of nucleosome assembly with DNA repeat sequences associated with hereditary neurological diseases2011

    • Author(s)
      諸橋伸行, 黒川和希, 松浦徹, 立和名博昭, 志賀達也, 香川亘, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] The effect of human telomeric repeat sequences on nucleosome positioning in yeast cells2011

    • Author(s)
      市川雄一, 諸橋伸行, 西村善文, 胡桃坂仁志, 清水光弘
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] CENP-T-W-S-X複合体は、動原体タンパク質群の集合機構に重要な役割を担う2011

    • Author(s)
      竹内康造, 西野達哉, 堀哲也, Karen E.Gascoigne, 立和名博昭, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Biochemical and structural analyses of the nucleosomes in transcriptionally active region2011

    • Author(s)
      有村泰宏, 立和名博昭, 小田隆, 佐藤衛, 胡桃坂仁志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Structural analysis of human nucleosomes containing H2A.Z-1 and H2A.Z-22011

    • Author(s)
      堀越直樹, 立和名博昭, 島田桂丞, 香川亘, 原田昌彦, 胡桃坂仁志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Chd2-dependent deposition of H3.3 is crucial for Brg1 recruitment in myogenesis2011

    • Author(s)
      原田哲仁, 小田原淳, 前原一満, 吉見智彦, 吉村小緒利, 立花太郎, 他
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] STRUCTURAL AND FUNCTIONAL ANALYSES OF HUMAN NUCLEOSOMES CONTAINING TESTIS-SPECIFIC HISTONE VARIANTS2011

    • Author(s)
      H.Kurumizaka
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Cairns (Australia)(招待講演)
    • Year and Date
      2011-10-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] INSTABILITY AND STRUCTURAL PROPERTY OF A HUMAN TESTIS-SPECIFIC HISTONE H3T NUCLEOSOME2011

    • Author(s)
      H.Tachiwana, A.Osakabe, T.Shiga, W.Kagawa, H.Kurumizaka
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Cairns (Australia)
    • Year and Date
      2011-10-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] ントロメア特異的なヌクレオソームの構造・生化学・細胞生物学的解析2011

    • Author(s)
      立和名博昭, 香川亘, 志賀達也, 越阪部晃永, …, 胡桃坂仁志
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNAリピート配列が形成するヌクレオソームの構造と機能2011

    • Author(s)
      清水光弘, 諸橋伸行, 立和名博昭, 志賀達也, 香川亘, 胡桃坂仁志
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒストンバリアントによるヌクレオソーム構造の多様性と機能発現2011

    • Author(s)
      胡桃坂仁志, 立和名博昭, 香川亘, 志賀達也, 越阪部晃永, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Structural similarity and versatility of the human nucleosomes2011

    • Author(s)
      H.Kurumizaka, H.Tachiwana, W.Kagawa, A.Osakabe, T.Shiga, et al
    • Organizer
      EMBO Conference Series Chromatin and Epigenetics
    • Place of Presentation
      Heidelberg (Germany)(招待講演)
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] The structural and biochemical analyses of centromere specific nucleosome2011

    • Author(s)
      H.Tachiwana, A.Osakabe, H.Kurumizaka, W.Kagawa, T.Shiga, et al
    • Organizer
      EMBO Conference Series Chromatin and Epigenetics
    • Place of Presentation
      Heidelberg (Germany)
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Identification and functional analyses of a novel histone interacting factor, human SPT22011

    • Author(s)
      A.Osakabe, H.Tachiwana, M.Takaku, H Kurumizaka, C.Obuse, et al
    • Organizer
      EMBO Conference Series Chromatin and Epigenetics
    • Place of Presentation
      Heidelberg (Germany)
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Atomic Resolution Structures of the Human Nucleosomes Containing Histone Variants2011

    • Author(s)
      Hitoshi Kurumizaka
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan(招待講演)
    • Year and Date
      2011-01-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Roles of the N-terminal and C-terminal domains of the Rad52 protein in homologous recombination repair2011

    • Author(s)
      Wataru Kagawa, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Biochemical and cell biological analyses of a novel histone interacting factor, SPT22011

    • Author(s)
      Akihisa Osakabe, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional analyses of the Fanconi anemia protein, FANCD22011

    • Author(s)
      Koichi Sato, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] The Crystal STructure of Centromere Specific Nucleosome2011

    • Author(s)
      Hiroaki Tachiwana, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] A novel homologous recomination factor, human EVL forms single-stranded DNA catemers with a type I topoisomerase2011

    • Author(s)
      Motoki Takaku, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Regulation of Radiation-induced focus formation by SUMOylation2011

    • Author(s)
      Hiroki Shima, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] C-terminal Tail of Histone H2AX Reduces Intra-nucleosome Array Interaction2011

    • Author(s)
      Noriyuki Suka, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Monitoring Histone Modifications in Single Cells using FabLEM (Fab-based Live Endogenous Modification Labeling)2011

    • Author(s)
      Yoko Hayashi-Takanaka, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] SLX4 links the Fanconi anemia pathway to structure-specific endonucleases, SLX1, XPF and MUS81 in interstrand crosslink repair2011

    • Author(s)
      Kimiyo N.Yamamoto, et al.
    • Organizer
      International Symposium of the Physicochemical Field for Genetic Activities
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2011-01-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] H2A.Bbdを含むヌクレオソームの生化学的解析2011

    • Author(s)
      有村泰宏, 他
    • Organizer
      第28回染色体ワークショップ
    • Place of Presentation
      加賀
    • Year and Date
      2011-01-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒストンH3バリアントCENP-Aを含むヌクレオソームのX線結晶構造解析2011

    • Author(s)
      立和名博昭, 他
    • Organizer
      第28回染色体ワークショップ
    • Place of Presentation
      加賀
    • Year and Date
      2011-01-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 出芽酵母Rad51によるD-loop形成促進のためのRad52第二DNA結合部位の機能2011

    • Author(s)
      新井直人, 他
    • Organizer
      第28回染色体ワークショップ
    • Place of Presentation
      加賀
    • Year and Date
      2011-01-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] Structural basis for formation of functional chromatin architecture2011

    • Author(s)
      Kurumizaka H
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      神奈川
    • Related Report
      2012 Final Research Report
  • [Presentation] INSTABILITY AND STRUCTURAL PROPERTY OF A HUMAN TESTIS-SPECIFIC HISTONE H3T NUCLEOSOME2011

    • Author(s)
      Kurumizaka H
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Cairns、Australia
    • Related Report
      2012 Final Research Report
  • [Presentation] ヒストンバリアントによるヌクレオソーム構造の多様性と機能発現2011

    • Author(s)
      胡桃坂仁志、立和名博昭、香川亘、志賀達也、越阪部晃永、堀越直樹、有村泰宏、宮優太、松本亮平
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Structural similarity and versatility of the human nucleosomes2011

    • Author(s)
      Kurumizaka H., Tachiwana H., Kagawa W., Osakae A., Shiga T., Miya Y., Matsumoto R
    • Organizer
      EMBO Conference Series Chromatin and Epigenetics
    • Place of Presentation
      Heidelberg、Germany
    • Related Report
      2012 Final Research Report
  • [Presentation] Atomic resolution structures of the human nucleosomes containing histone variants.2011

    • Author(s)
      Kurumizaka, H.
    • Organizer
      International Symposium on the Physcochemical Field for Genetic Activities.
    • Place of Presentation
      Awaji, Japan.
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 新規ヒストン結合因子ヒトSPT2のDNA損傷修復における機能解析2010

    • Author(s)
      越坂部晃永, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] セントロメア領域に特異的なヌクレオソームのX線結晶構造解析2010

    • Author(s)
      立和名博昭, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] NMRによるヒストンヌクレオソームコアの立体構造解析2010

    • Author(s)
      森脇義仁, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 質量分析を用いたヒストンH2A-H2Bのシトルリン化の解析2010

    • Author(s)
      浅野裕輝, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] CENP-Aターゲッティングドメインを含むH3変異体が形成するヌクレオソームのX線結晶構造解析2010

    • Author(s)
      志賀達也, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] ファンコニ貧血原因遺伝子産物FANCD2およびFANCIの複合体形成と機能解析2010

    • Author(s)
      佐藤浩一, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Chd2 interacts with H3.3 to determine cell fate in myogenesis2010

    • Author(s)
      Akihito Harada, et al.
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] DNA結合活性を有するCCANタンパク質群の機能解析2010

    • Author(s)
      竹内康造, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 酵母とヒトDNA修復タンパク質Rad52の機能ドメイン解析2010

    • Author(s)
      香川亘, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒストンバリアントを含むヌクレオソームの構造多様性と機能2010

    • Author(s)
      胡桃坂仁志, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生細胞におけるメチル化およびアセチル化修飾ヒストンの可視化2010

    • Author(s)
      林陽子, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] RAD51によるparanemic joint molecule形成過程へのtopoisomerase III αの役割2010

    • Author(s)
      高久誉大, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規RAD51組換え活性制御化合物の同定とその作用機序2010

    • Author(s)
      石田恭子, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] PSFによるDNA組換え酵素DMC1の活性化2010

    • Author(s)
      両角佑一, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 出芽酵母Rad52の第二DNA結合部位も相同組換えに必要である2010

    • Author(s)
      新井直人, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] DNA修復タンパク質RAD52の翻訳後修飾による機能制御機構の解析2010

    • Author(s)
      齋藤健吾, 他
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヌクレオソームの立体構造からみたエピジェネティクスの分子機構2010

    • Author(s)
      胡桃坂仁志
    • Organizer
      第21回フォーラム・イン・ドージン エピジェネティクスによる細胞のメタモルフォーゼ
    • Place of Presentation
      熊本(招待講演)
    • Year and Date
      2010-11-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Structual and biochemical studies of DMC1 polymorphisms in the human population2010

    • Author(s)
      Hitoshi Kurumizaka
    • Organizer
      European Genomics Meeting & European Neurodegenerative Diseases-2010-Meeting
    • Place of Presentation
      Oxford, United Kingdom(招待講演)
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒトと酵母のDNA修復タンパク質Rad52の機能比較2010

    • Author(s)
      齋藤健吾, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] ブーケ配向形成因子S.japonicas Bqt1-Bqt2複合体の生化学的解析2010

    • Author(s)
      市川雄一, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] シトルリン化タンパク質PAD4のSNP変異体の解析2010

    • Author(s)
      堀越直樹, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 低分子化合物によるRAD51依存的相同組換え反応の制御2010

    • Author(s)
      石田恭子, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Fanconi貧血原因遺伝子FANCD2及びFANCIの機能解析2010

    • Author(s)
      佐藤浩一, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒストンシャペロンsNASPの生化学的解析2010

    • Author(s)
      越坂部晃永, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] SUMO修飾システムによるRAD51核内ドメイン形成の制御2010

    • Author(s)
      島弘季, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規RAD51活性化因子GEMIN2の相同組換え修復における機能2010

    • Author(s)
      高久誉大, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒストンバリアントH3Tを含むヌクレオソームの構造解析および生化学的解析2010

    • Author(s)
      立和名博昭, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Rad52タンパク質のDNA positive supercoiling活性の役割2010

    • Author(s)
      香川亘, 他
    • Organizer
      第9回核ダイナミクス研究会
    • Place of Presentation
      伊豆
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒストンバリアントを含むヌクレオソームの構造多様性と機能2010

    • Author(s)
      胡桃坂仁志、立和名博昭、香川亘、志賀達也、越阪部晃永、林(高中)陽子、木村宏
    • Organizer
      Biochemistry and Molecular Biology 2010
    • Place of Presentation
      兵庫
    • Related Report
      2012 Final Research Report
  • [Presentation] ヌクレオソームの立体構造からみたエピジェネティクスの分子機構2010

    • Author(s)
      胡桃坂仁志
    • Organizer
      第21回フォーラム・イン・ドージン エピジェネティクスによる細胞のメタモルフォーゼ
    • Place of Presentation
      熊本
    • Related Report
      2012 Final Research Report
  • [Presentation] 高等動物のセントロメアクロマチン構造2010

    • Author(s)
      堀哲也, 立和名博昭, 越坂部晃永, 志賀達也, 香川亘, 胡桃坂仁志
    • Organizer
      第27回染色体ワークショップ
    • Place of Presentation
      御殿場高原ホテルB.U
    • Related Report
      2009 Annual Research Report
  • [Presentation] セントロメァ特異的なCENP-Aヌクレオソームの生化学的解析2010

    • Author(s)
      立和名博昭, 川口紘一郎, 越坂部晃永, 志賀達也, 香川亘, 胡桃坂仁志
    • Organizer
      第27回染色体ワークショップ
    • Place of Presentation
      御殿場高原ホテルB.U
    • Related Report
      2009 Annual Research Report
  • [Presentation] SPTY2D1のヒストン結合および機能解析2010

    • Author(s)
      越坂部晃永, et al.
    • Organizer
      第27回染色体ワークショップ
    • Place of Presentation
      御殿場高原ホテルB.U
    • Related Report
      2009 Annual Research Report
  • [Presentation] 相同DNA組換えにおける2種の相同DNA対合蛋白質の役割分担2010

    • Author(s)
      柴田武彦, et al.
    • Organizer
      第27回染色体ワークショップ
    • Place of Presentation
      御殿場高原ホテルB.U
    • Related Report
      2009 Annual Research Report
  • [Presentation] ブーケ配向形成因子S.japonicus Bqt1-Bqt2複合体の精製および機能解析2010

    • Author(s)
      市川雄一, 香川亘, 近重祐次, 平野泰弘, 原口徳子, 平岡泰, 胡桃坂仁志
    • Organizer
      第27回染色体ワークショップ
    • Place of Presentation
      御殿場高原ホテルB.U
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒトSPF45の相同組換えにおける機能解析2010

    • Author(s)
      堀越直樹, 両角佑一, 高久誉大, 胡桃坂仁志
    • Organizer
      第27回染色体ワークショップ
    • Place of Presentation
      御殿場高原ホテルB.U
    • Related Report
      2009 Annual Research Report
  • [Presentation] 精巣特異的に高発現するH3バリアントH3tを含むヌクレオソームの構造解析2009

    • Author(s)
      立和名博昭、川口紘一郎、越阪部晃永、香川亘、横山茂之、胡桃坂仁志
    • Organizer
      第26回染色体ワークショップ
    • Place of Presentation
      姫路
    • Year and Date
      2009-01-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] ピストンH3バリアントと相互作用する因子群の同定および生化学的解析2009

    • Author(s)
      越阪部晃永、他
    • Organizer
      第26回染色体ワークショップ
    • Place of Presentation
      姫路
    • Year and Date
      2009-01-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Fanconi貧血原因遺伝子FANCD2の機能解析2009

    • Author(s)
      佐藤浩一、他
    • Organizer
      第26回染色体ワークショップ
    • Place of Presentation
      姫路
    • Year and Date
      2009-01-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] クロマチンの基盤構造であるヌクレオソームの機能・構造解析2009

    • Author(s)
      胡桃坂仁志、立和名博昭、越阪部晃永、川口紘一郎、香川亘
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      神奈川
    • Related Report
      2012 Final Research Report
  • [Presentation] Stractual and functional analyses of the nucleosome containing a testis-specific histone variant, human H3T2009

    • Author(s)
      Kurumizaka H
    • Organizer
      The EMBO Conference on Meiosis (1st)
    • Place of Presentation
      Avignon、France
    • Related Report
      2012 Final Research Report
  • [Presentation] リコンビナントヒストンによるin vitroヌクレオソーム再構築2009

    • Author(s)
      胡桃坂仁志
    • Organizer
      第8回核ダイナミクス研究会
    • Place of Presentation
      静岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Rad52の立体構造に基づく相同組換え反応機構の解析2009

    • Author(s)
      香川亘, 斉藤健吾, 胡桃坂仁志
    • Organizer
      第8回核ダイナミクス研究会
    • Place of Presentation
      ラフォーレ修善寺
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒトSUMO化Rad52の生化学的および物理化学的解析2009

    • Author(s)
      斉藤健吾, 香川亘, 胡桃坂仁志
    • Organizer
      第8回核ダイナミクス研究会
    • Place of Presentation
      ラフォーレ修善寺
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規RAD51相互作用タンパク質PSFの相同組換えにおける機能2009

    • Author(s)
      両角佑一, 滝沢由政, 高久誉大, 胡桃坂仁志
    • Organizer
      第8回核ダイナミクス研究会
    • Place of Presentation
      ラフォーレ修善寺
    • Related Report
      2009 Annual Research Report
  • [Presentation] リコンピナントヒストンによるin vitroヌクレオソーム再構築2009

    • Author(s)
      胡桃坂仁志
    • Organizer
      第8回核ダイナミクス研究会
    • Place of Presentation
      ラフォーレ修善寺
    • Related Report
      2009 Annual Research Report
  • [Presentation] Stractual and funotional analyses of the nucleosome containing a testis-specific histone variant, human H3T2009

    • Author(s)
      胡桃坂仁志, 立和名博昭, 香川亘, 越坂部晃永, 川口紘一郎, 志賀達也
    • Organizer
      The EMBO Conference on Meiosis(1st)
    • Place of Presentation
      Isle sur la Sorgue/France
    • Related Report
      2009 Annual Research Report
  • [Presentation] 相同DNA組換えにおける天然変性領域の機能2009

    • Author(s)
      柴田武彦, 新井直人, 凌楓, 番川亘, 胡桃坂仁志, 井上仁, 新宮良宣, 美川務
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Related Report
      2009 Annual Research Report
  • [Presentation] シトルリン化によるヒストンH2A/H2Bの構造変化2009

    • Author(s)
      下山真吾, et al.
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒストンバリアントH3tを含むヌクレオソームの立体構造とその機能解析2009

    • Author(s)
      立和名博昭, et al.
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fanconi貧血原因遺伝子産物FANCD2のヌクレオソーム形成活性2009

    • Author(s)
      佐藤浩一, et al.
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規RAD51結合タンパク質EVLの機能解析2009

    • Author(s)
      高久誉大, 町田晋一, 細谷紀子, 宮川清, 胡桃坂仁志
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Related Report
      2009 Annual Research Report
  • [Presentation] クロマチンの基盤構造であるヌクレオソームの機能・構造解析2009

    • Author(s)
      胡桃坂仁志, 立和名博昭, 越坂部晃永, 川口紘一郎, 香川亘
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      バシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] Structural feature of the CENP-A nucleosome in the vertebrate centromere2009

    • Author(s)
      堀哲也, et al.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] ブーケ配向形成因子S.japonicus Byt1-Bqt2複合体の大量精製および生化学的解析2009

    • Author(s)
      市川雄一, 香川亘, 近重祐次, 原口徳子, 平岡泰, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fanconi貧血原因遺伝子FANCD2およびFANCIの生化学的機能解析2009

    • Author(s)
      佐藤浩一, et al.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] セントロメア特異的H3バリアントCENP-Aを含むヌクレオソームの構造解析2009

    • Author(s)
      立和名博昭, 香川亘, 志賀達也, 川口紘一郎, 越坂部晃永, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] セントロメアDNA結合タンパク質CENP-T/CENP-W複合体の生化学的解析2009

    • Author(s)
      竹内康造, 堀哲也, 立和名博昭, 越坂部晃永, 胡桃坂仁志, 深川竜郎
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] 出芽酵母におけるヒト由来ヒストンH3バリアントの発現と機能解析2009

    • Author(s)
      早川新一, 諸橋伸行, 立和名博昭, 胡桃坂仁志, 清水光弘
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシコィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト相同組換えタンパク質DMC1と相互作用する新規タンパク質PLEKHF1の生化学的機能解析2009

    • Author(s)
      岩下紗美香, 高久誉大, 引場樹里, 滝沢由政, 小布施力史, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] GEMIN2によるRAD51組換え活性の制御2009

    • Author(s)
      高久誉大, 滝沢由政, 辻田幹, 石田恭子, 両角佑―, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒトRAD51と相互作用する新規タンパク質PSFの機能解析2009

    • Author(s)
      両角佑一, 滝沢由政, 高久誉大, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] 出芽酵母Rad52-Rad51複合体によるD-loop形成におけるRAD52の二本鎖DNAへの結合の影書D-loop形成においてRad52は二本鎖DNAの結合に働く2009

    • Author(s)
      新井直人, 香川亘, 美川務, 胡桃坂仁志, 柴田武彦
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] DNA配列を改変したヌクレオソーム複合体の生産技術開発2009

    • Author(s)
      若森昌聡, et al.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規ヒストン結合因子SPTY2D1の機能解析2009

    • Author(s)
      越坂部晃永, 野澤竜介. 立和名博昭, 小布施力史, 深川竜郎, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] 大腸菌染色体分配に関わる候補因子MigP(YncE)の構造生物学的解析2009

    • Author(s)
      香川亘, 佐川智彦, 仁木宏典, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] HP1とPOGZの生化学的および構造生物学的解析2009

    • Author(s)
      島田桂丞, 立和名博昭, 越坂部晃永, 野澤竜介, 小布施力史, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] RAD51と相互作用するSMN-GEMIN2複合体の生化学的解析2009

    • Author(s)
      辻田幹, 高久誉大, 滝沢由政, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] DNA修復タンパク質RAD52のヒトと酵母における機能比較2009

    • Author(s)
      斉藤健吾, 香川亘, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規相同組換え修復タンパク質ヒトSPF45の生化学的解析2009

    • Author(s)
      堀越直樹, 両角佑一, 高久誉大, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] 低分子化合物を用いた組換え修復タンパク質RAD51の活性制御2009

    • Author(s)
      海沼嵩, 石田巷子, 柴田武彦, 胡桃坂仁志
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] ゲノム配列情報の安定維持と多様化に重要な相同組換え因子群の機能解析2008

    • Author(s)
      胡桃坂仁志
    • Organizer
      Biochemistry and Molecular Biology 2008
    • Place of Presentation
      兵庫
    • Related Report
      2012 Final Research Report
  • [Book] SPring-8 Research Frontiers2011

    • Author(s)
      Tachiwana H., Kagawa W., Kurumizaka H
    • Publisher
      ROKKO Publishing & Sale Co.
    • Related Report
      2012 Final Research Report
  • [Book] 実験医学別冊 目的別で選べる核酸実験の原理とプロトコール2011

    • Author(s)
      平尾一郎、胡桃坂仁志 編
    • Publisher
      羊土社
    • Related Report
      2012 Final Research Report
  • [Book] 最新医学 第65巻/6月増刊号 発がん防御に重要な相同組換えの分子機構2010

    • Author(s)
      齊藤健吾、香川亘、胡桃坂仁志
    • Publisher
      最新医学社
    • Related Report
      2012 Final Research Report
  • [Book] 発がん防御に重要な相同組換えの分子機構、乳癌-基礎と臨床の架け橋-2010

    • Author(s)
      齊藤健吾、香川亘、胡桃坂仁志
    • Publisher
      最新医学社
    • Related Report
      2010 Self-evaluation Report
  • [Book] 実験医学2009

    • Author(s)
      立和名博昭、胡桃坂仁志
    • Total Pages
      7
    • Publisher
      羊土社
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2018-03-28  

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