| Budget Amount *help |
¥61,750,000 (Direct Cost: ¥47,500,000、Indirect Cost: ¥14,250,000)
Fiscal Year 2012: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2011: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2010: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Fiscal Year 2009: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2008: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
|
|---|
| Research Abstract |
F1-ATPase is a rotary molecular motor which couples the hydrolysis/synthesis of ATP molecule with the rotation of internal γsubunit. We imposed an opposing external torque to find stall torque under various conditions. From the stall torque, we demonstrated that the F1-ATPase converts the free energy of ATP hydrolysis to the kinetic energy of the rotation at nearly 100 % efficiency. At far from equilibrium, by measuring the nonequilibrium fluctuation, we demonstrated that the F1-ATPase dissipates the free energy of ATP hydrolysis in the rotational degree of freedom at nearly 100 % efficiency. Furthermore, we found that these remarkable properties were well explained by the shape of driving potential and the timing of its switching.
|
