| Budget Amount *help |
¥136,370,000 (Direct Cost: ¥104,900,000、Indirect Cost: ¥31,470,000)
Fiscal Year 2024: ¥23,010,000 (Direct Cost: ¥17,700,000、Indirect Cost: ¥5,310,000)
Fiscal Year 2023: ¥23,010,000 (Direct Cost: ¥17,700,000、Indirect Cost: ¥5,310,000)
Fiscal Year 2022: ¥23,010,000 (Direct Cost: ¥17,700,000、Indirect Cost: ¥5,310,000)
Fiscal Year 2021: ¥21,840,000 (Direct Cost: ¥16,800,000、Indirect Cost: ¥5,040,000)
Fiscal Year 2020: ¥45,500,000 (Direct Cost: ¥35,000,000、Indirect Cost: ¥10,500,000)
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| Outline of Final Research Achievements |
The mechanism by which the myriad complex connections between the visual areas of the cortex and their corresponding retinal coordinates are formed was unknown. We elucidated the mechanism by which these numerous and complex inter-area connections form without confusion within the brief period between birth and opening the eyes. We showed that, before interdomain connections form, a pathway connecting the retina and multiple visual areas in the cortex forms first. Information indicating the retina's location is transmitted to multiple visual areas via spontaneous activity of retinal origin that propagates along this pathway. This activity serves as a teacher signal that precisely connects locations corresponding to retinal coordinates in multiple visual areas of the cortex. This information is then used to form connections that precisely link the corresponding retinal coordinates in multiple visual areas of the cortex (Murakami et al., 2022, Nature).
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