| Budget Amount *help |
¥33,150,000 (Direct Cost: ¥25,500,000、Indirect Cost: ¥7,650,000)
Fiscal Year 2013: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2012: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2009: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Outline of Final Research Achievements |
Highly strained cyclic acetylenes, Sondheimer-Wong diynes having various substituents on their benzene rings could be synthesized by one-pot treatment of the corresponding formylsulfones with diethyl chlorophosphate/lithium hexamethyldisilazide (LiHMDS) and lithium diisopropylamide (LDA). When a mixture of two types of formylsulfones bearing different substituents were subjected to this protocol, the unsymmetrically substituted Sondheimer-Wong diynes could be synthesized in a stepwise manner; the isolation of hetero-coupling vinylsulfone intermediates followed by their treatment with LDA. The UV-vis absorption spectra and cyclic voltammetries of the substituted Sondheimer-Wong diynes were recorded. The electronic effect of substituents on the diynes was investigated in their click reaction and nucleophilic and electrophilic additions.
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