| Budget Amount *help |
¥122,460,000 (Direct Cost: ¥94,200,000、Indirect Cost: ¥28,260,000)
Fiscal Year 2013: ¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2012: ¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2011: ¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2010: ¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2009: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
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| Research Abstract |
Intrinsically disordered proteins (IDPs) are those that do not adopt their unique tertiary structures under physiological condition, if isolated from their binding partners. The structural and functional information for IDPs are not adequate enough, because they have been paid attention recently. They play significant roles in the translational activation or signal transduction. Construction of qualified database is mandatory to the deep understanding of IDPs. We have developed IDEAL database using the information of UniProt and PDB as the starting point. We arranged manual-annotation procedures and devised several data-handling tools. From the November 2011, IDEAL is open to the public. Especially, it presents functional regions in disordered regions that exhibit disorder-order transition upon binding of interaction partners, as protean segments.
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