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Generation of meta-rule through dynamical systems with multiple timescales: towards a theory of learning and evolution

Planned Research

Project AreaThe study on the neural dynamics for understanding communication in terms of complex hetero systems
Project/Area Number 21120004
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionThe University of Tokyo

Principal Investigator

KANEKO Kunihiko  東京大学, 総合文化研究科, 教授 (30177513)

Project Period (FY) 2009-07-23 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥49,400,000 (Direct Cost: ¥38,000,000、Indirect Cost: ¥11,400,000)
Fiscal Year 2013: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
Fiscal Year 2012: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
Fiscal Year 2011: ¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
Fiscal Year 2010: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2009: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywords力学系 / カオス的遍歴 / 可塑性 / 学習 / 進化
Research Abstract

Biological systems consists of hierarchy with different time scales.
Slow units provide a rule for faster units, while the former are changed by the latter, as seen in the relation between synapse change and neural activity in learning, or phenotypic change by the genotype in evolution. Development and adaptation also consist of such hierarchy of time scales. We study such dynamics of dynamical systems; (1)memory and learning of input-output relationship as bifurcation(2) stem cell differentiation as interaction-induced bifurcation of intra-cellular dynamical systems (3)high-dimensional adaptation dynamics (4)evolutionary correspondence between genotypic variation and phenotypic dynamics; evolution of rules of robust dynamics (5) chaotic itinerancy of fast-slow dynamics. With this study, we uncover how heterogeneous dynamical systems lead to plastic and robust generation of rules that govern the system itself, thereby providing a basis for mathematical study of biological systems

Report

(6 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (117 results)

All 2013 2012 2011 2010 2009 Other

All Journal Article (28 results) (of which Peer Reviewed: 28 results) Presentation (85 results) (of which Invited: 14 results) Book (4 results)

  • [Journal Article] The Baldwin effect under multi-peaked fitness landscapes : Phenotypic fluctuation acceleratesevolutionary rate2013

    • Author(s)
      N. Saito, S. Ishihara, and K. Kaneko
    • Journal Title

      Phys. Rev. E

      Volume: 87 Issue: 5 Pages: 52701-52701

    • DOI

      10.1103/physreve.87.052701

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Embedding Responses in Spontaneous Neural Activity Shaped through Sequential Learning2013

    • Author(s)
      Tomoki Kurikawa & Kunihiko Kaneko
    • Journal Title

      PLoS Comput Biol

      Volume: 9(3):e1002943 Issue: 3 Pages: e1002943-e1002943

    • DOI

      10.1371/journal.pcbi.1002943

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Minimal Model for Stem-Cell Differentiation2013

    • Author(s)
      Y. Goto and K. Kaneko
    • Journal Title

      Phys. Rev. E

      Volume: 88(2013) Issue: 3 Pages: 32718-32718

    • DOI

      10.1103/physreve.88.032718

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cooperative Adaptive Response in Gene Regulatory Networks with Many Degrees of Freedom2013

    • Author(s)
      Masayo Inoue, Kunihiko Kaneko
    • Journal Title

      PLos Computational Biology

      Volume: 9 Issue: 4 Pages: e1003001-e1003001

    • DOI

      10.1371/journal.pcbi.1003001

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Slow Stochastic Switching by Collective Chaos of Fast Elements2013

    • Author(s)
      H. Aoki and K. Kaneko
    • Journal Title

      Phys. Rev. Lett.

      Volume: 111 Issue: 14 Pages: 144102-144102

    • DOI

      10.1103/physrevlett.111.144102

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Epigenetic feedback regulation accelerates adaptation and evolution2013

    • Author(s)
      Chikara Furusawa and Kunihiko Kaneko
    • Journal Title

      PLoS One

      Volume: 8 Issue: 5 Pages: e61251-e61251

    • DOI

      10.1371/journal.pone.0061251

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evolution of Robustness and Plasticity under Environmental Fluctuation : Formulation in terms of Phenotypic Variances2012

    • Author(s)
      K. Kaneko
    • Journal Title

      J. Stat. Phys.

      Volume: 148 Issue: 4 Pages: 686-704

    • DOI

      10.1007/s10955-012-0563-1

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Replica symmetry breaking in an adiabatic spin-glass model of adaptive evolution2012

    • Author(s)
      Ayaka Sakata, Koji Hukushima and Kunihiko Kaneko
    • Journal Title

      Europhysics Letteres

      Volume: 99 Issue: 6 Pages: 68004-68004

    • DOI

      10.1209/0295-5075/99/68004

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associative memory model with spontaneous neural activity2012

    • Author(s)
      Tomoki Kurikawa & Kunihiko Kaneko
    • Journal Title

      Europhysics Letters

      Volume: 98 Issue: 4 Pages: 48002-48002

    • DOI

      10.1209/0295-5075/98/48002

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Dynamical-Systems View of Stem Cell Biology2012

    • Author(s)
      C. Furusawa and K. Kaneko
    • Journal Title

      Science

      Volume: 338 Issue: 6104 Pages: 215-217

    • DOI

      10.1126/science.1224311

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adaptation to optimal cell growth through self-organized criticality2012

    • Author(s)
      C. Furusawa and K. Kaneko
    • Journal Title

      Phys. Rev. Lett.

      Volume: 108 Issue: 20 Pages: 208103-208103

    • DOI

      10.1103/physrevlett.108.208103

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Learning to Memorize Input-Output Mapping as Bifurcation in Neural Dynamics; Relevance of Multiple Timescales for Synapse Changes2012

    • Author(s)
      Tomoki Kurikawa
    • Journal Title

      Neural Computing and Applications

      Volume: 21 Issue: 4 Pages: 725-734

    • DOI

      10.1007/s00521-011-0650-2

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phenotypic Plasticity and Robustness: Evolutionary Stability Theory, Gene Expression Dynamics Model, and Laboratory Experiments2012

    • Author(s)
      Kunihiko Kaneko
    • Journal Title

      Evolutionary Systems Biology (Springer, ed. Orkun S. Soyer)

      Volume: * Pages: 249-278

    • DOI

      10.1007/978-1-4614-3567-9_12

    • ISBN
      9781461435662, 9781461435679
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Learning Shapes Spontaneous Activity Itinerating over Memorized States2011

    • Author(s)
      Tomoki Kurikawa, Kunihiko Kaneko
    • Journal Title

      PLoS ONE

      Volume: 6(3)-e17432 Issue: 3 Pages: e17432-e17432

    • DOI

      10.1371/journal.pone.0017432

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oscillatory Protein Expression Dynamics Endows Stem Cells with Robust DifferentiationPotential2011

    • Author(s)
      N. Suzuki, C. Furusawa, and K. Kaneko
    • Journal Title

      PLoS One

      Volume: 6 Issue: 11 Pages: e27232-e27232

    • DOI

      10.1371/journal.pone.0027232

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of stem cells and cancer cells on the basis of gene expression profile stability, plasticity and robustness2011

    • Author(s)
      K. Kaneko
    • Journal Title

      Bioessays

      Volume: 33 Issue: 6 Pages: 403-413

    • DOI

      10.1002/bies.201000153

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oscillatory Protein Expression Dynamics Endows Stem Cells with Robust Differentiation Potential2011

    • Author(s)
      Narito Suzuki, Chikara Furusawa, Kunihiko Kaneko
    • Journal Title

      PLoS One

      Volume: 6

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Learning to Memorize Input-Output Mapping as Bifurcation in Neural Dynamics ; Relevance of Multiple Timescales for Synapse Changes2011

    • Author(s)
      Tomoki Kurikawa, Kunihiko Kaneko
    • Journal Title

      Neural Computing and Applications

      Volume: (Online First)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluctuation and response in biology2011

    • Author(s)
      B.Lehner, K.Kaneko
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 68 Pages: 1005-1010

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A macroscopic relationship between fluctuation and response in biology2011

    • Author(s)
      B.Lehner, K.Kaneko
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 68 Pages: 1005-1010

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Proportionality between Variances in Gene Expression Induced by Noise and Mutation : Consequence of Evolutionary Robustness2011

    • Author(s)
      K.Kaneko
    • Journal Title

      BMC Evolutionary Biology

      Volume: 11

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Learning Shapes Spontaneous Activity Itinerating over Memorized States2011

    • Author(s)
      T.Kurikawa, K.Kaneko
    • Journal Title

      PLoS One

      Volume: 6

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamical systems modeling of continuous flash suppression2011

    • Author(s)
      D.Shimaoka, K.Kaneko
    • Journal Title

      Vision Research

      Volume: 51 Pages: 521-528

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Learning Shapes Bifurcations of Neural Dynamics upon External Stimuli2010

    • Author(s)
      T.Kurikawa, K.Kaneko
    • Journal Title

      Lecture Notes in Computer Science

      Volume: 6443 Pages: 153-160

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamics.of Coupled Adatpive Elements : Bursting and Intermitteny Oscillations Generated by Frustration in the Network2010

    • Author(s)
      M.Inoue, K.Kaneko
    • Journal Title

      Phys.Rev.E

      Volume: 81

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transient process of cortical activity during Necker cube perception : from local clusters to global synchrony2010

    • Author(s)
      Daisuke Shimaoka, Keiichi Kitajo, Kunihiko Kaneko, Yoko Yamaguchi
    • Journal Title

      Nonlinear Biomedical Physics

      Volume: 4(Suppl 1)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Learning to Memorize Input-Output Mapping as Bifurcation in Neural Dynamics ; Relevance of Multiple Timescales for Synapse Changes

    • Author(s)
      T.Kurikawa, K.Kaneko
    • Journal Title

      Neural Computing and Applications

      Volume: (in press、掲載確定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of stem cells and cancer cells on the basis of gene expression profile stability, plasticity and robustness

    • Author(s)
      K.Kaneko
    • Journal Title

      Bioessays

      Volume: (in press、掲載確定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Plasticity and Robustness in Evolution : Macroscopic Theory, Model Simulations, and Laboratory Experiments -Part I&II2013

    • Author(s)
      K. Kaneko
    • Organizer
      Quantitative Laws of Genome Evolution
    • Place of Presentation
      Villa del Grumello (Como,イタリア)
    • Year and Date
      2013-07-02
    • Related Report
      2013 Final Research Report
  • [Presentation] Dynamical-Systems Perspective to Stem-cell Biology : Relevance of oscillatory gene expression dynamics and cell-cell interaction2013

    • Author(s)
      K.Kaneko
    • Organizer
      Symposium on Systems Biology of Stem Cells
    • Place of Presentation
      Beckman center (Irvine,米国)
    • Year and Date
      2013-06-10
    • Related Report
      2013 Final Research Report
  • [Presentation] 遺伝型-表現型マッピングの統計力学モデルの解析2013

    • Author(s)
      斉藤稔
    • Organizer
      第68回日本物理学会年会
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2013-03-28
    • Related Report
      2012 Annual Research Report
  • [Presentation] 触媒反応ネットワークの進化とマクロ現象論の可能性2013

    • Author(s)
      金子邦彦
    • Organizer
      第68回日本物理学会年会
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2013-03-27
    • Related Report
      2012 Annual Research Report
  • [Presentation] 酵素の取り合いを介した細胞記憶の形成2013

    • Author(s)
      畠山哲央
    • Organizer
      第68回日本物理学会年会
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2013-03-27
    • Related Report
      2012 Annual Research Report
  • [Presentation] 遺伝子ネットワークによる非周期パターン形成の仕組み及びその進化III2013

    • Author(s)
      香曽我部隆裕
    • Organizer
      第68回日本物理学会年会
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2013-03-27
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生きていることの状態論――生命システムの可塑性と安定性2013

    • Author(s)
      金子邦彦
    • Organizer
      自然科学研究機構プロジェクト 合同シンポジウム「脳神経情報の階層的研究」「機能生命科学における揺らぎと決定」
    • Place of Presentation
      自然科学研究機構・生理学研究所(愛知)
    • Year and Date
      2013-03-05
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Phenotypic #64258;uctuation accelerates evolution2013

    • Author(s)
      Nen Saito
    • Organizer
      the First Annual Winter q-bio Meeting
    • Place of Presentation
      Hilton Hawaiian Village in Waikiki(ハワイ)
    • Year and Date
      2013-02-20
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cooperative adaptive responses in gene regulatory networks with many degrees of freedom2013

    • Author(s)
      Masayo Inoue
    • Organizer
      the First Annual Winter q-bio Meeting
    • Place of Presentation
      Hilton Hawaiian Village in Waikiki(ハワイ)
    • Year and Date
      2013-02-20
    • Related Report
      2012 Annual Research Report
  • [Presentation] Homeostasis and Memory by Autonomous Regulation of Time-scales by Enzyme-limited Competition2013

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Bioinspired - Methods and Applications
    • Place of Presentation
      東京大学生産技術研究所(東京)
    • Year and Date
      2013-02-05
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Biological Homeostasis by Autonomous Regulation of Enzyme Concentration2012

    • Author(s)
      金子邦彦
    • Organizer
      2nd Discussion Symposium on Artificial Life and Biomimetic Functional Materials
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-12-11
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] "Plasticity and Robustness in Development and Evolution: Perspective from2012

    • Author(s)
      金子邦彦
    • Organizer
      理化学研究所 生命システム研究センター 開所記念国際シンポジウム“Towards Whole-Cell Modeling”
    • Place of Presentation
      QBiC(神戸)
    • Year and Date
      2012-11-07
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] AEIOU neuron model and columnar dynamics resulting from slow adaptation currents.2012

    • Author(s)
      David Colliaux
    • Organizer
      The NeuroComp/KEOpS’12 workshop
    • Place of Presentation
      Functional Genomics Center(フランス)
    • Year and Date
      2012-10-11
    • Related Report
      2012 Annual Research Report
  • [Presentation] 表現型ゆらぎによる進化の促進2012

    • Author(s)
      斉藤稔
    • Organizer
      研究会「理論と実験」2012
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2012-10-06
    • Related Report
      2012 Annual Research Report
  • [Presentation] 遺伝子ネットワークで制御されるパターンの進化2012

    • Author(s)
      香曽我部隆裕
    • Organizer
      研究会「理論と実験」2012
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2012-10-06
    • Related Report
      2012 Annual Research Report
  • [Presentation] ニューラルネットワークの入力による分岐構造と学習による変化2012

    • Author(s)
      栗川知己
    • Organizer
      RIMS研究集会“力学系の作る集団ダイナミクス”
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2012-09-28
    • Related Report
      2012 Annual Research Report
  • [Presentation] Spontaneous and Evoked Neural Activities Shaped through A Sequential Learning Process2012

    • Author(s)
      栗川知己
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      名古屋大学(愛知)
    • Year and Date
      2012-09-23
    • Related Report
      2012 Annual Research Report
  • [Presentation] 自律的酵素量制御による時間スケール調整;ホメオスタシスと記憶2012

    • Author(s)
      金子邦彦
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      名古屋大学(愛知)
    • Year and Date
      2012-09-22
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 遺伝子制御ネットワークによる非周期空間パターン形成の仕組み及びその進化 II2012

    • Author(s)
      香曽我部隆裕
    • Organizer
      日本物理学会 2012年秋季大会
    • Place of Presentation
      横浜国立大学(神奈川)
    • Year and Date
      2012-09-21
    • Related Report
      2012 Annual Research Report
  • [Presentation] 学習過程にそった自発・誘起活動の総空間構造の変化2012

    • Author(s)
      栗川知己
    • Organizer
      日本物理学会 2012年秋季大会
    • Place of Presentation
      横浜国立大学(神奈川)
    • Year and Date
      2012-09-21
    • Related Report
      2012 Annual Research Report
  • [Presentation] 進化の情報理論による解析2012

    • Author(s)
      斉藤稔
    • Organizer
      日本物理学会 2012年秋季大会
    • Place of Presentation
      横浜国立大学(神奈川)
    • Year and Date
      2012-09-19
    • Related Report
      2012 Annual Research Report
  • [Presentation] 大自由度遺伝子発現制御モデルにおける適応応答の制御的進化2012

    • Author(s)
      井上雅世
    • Organizer
      日本物理学会 2012年秋季大会
    • Place of Presentation
      横浜国立大学(神奈川)
    • Year and Date
      2012-09-19
    • Related Report
      2012 Annual Research Report
  • [Presentation] 多峰適応度地形上でのボールドウィン効果2012

    • Author(s)
      斉藤稔
    • Organizer
      日本数理生物学会
    • Place of Presentation
      岡山大学(岡山)
    • Year and Date
      2012-09-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] Relationship Between Spontaneous Activity And Its Response to An External Input Shaped Through Learning2012

    • Author(s)
      栗川知己
    • Organizer
      日本神経回路学会
    • Place of Presentation
      名古屋工業大学(愛知)
    • Year and Date
      2012-09-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] 大自由度遺伝子発現制御モデルにおける適応応答の制御的進化2012

    • Author(s)
      井上雅世
    • Organizer
      広島大学大学院理学研究科 第4回公開シンポジウム
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2012-09-06
    • Related Report
      2012 Annual Research Report
  • [Presentation] Spontaneous and Evoked Neural Activities Shaped through A Sequential Learning Process2012

    • Author(s)
      Tomoki Kurikawa
    • Organizer
      Dynamic Brain Forum
    • Place of Presentation
      El Parador(セビリア)
    • Year and Date
      2012-09-05
    • Related Report
      2012 Annual Research Report
  • [Presentation] Characterization of stem cells and cancer cells on the basis of gene expression dynamics and robustness2012

    • Author(s)
      K. Kaneko
    • Organizer
      Sumeer school"DNA synamics and life strategies"
    • Place of Presentation
      Krogerup Hoejskole(デンマーク)
    • Year and Date
      2012-08-15
    • Related Report
      2013 Final Research Report
  • [Presentation] Biological Homeostasis: Adaptation by Catalytic Reaction Networks and Temperature Compensation in Biological Rhythm2012

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      summer school "DNA dynamics and life strategies"
    • Place of Presentation
      Krogerup Hoejskole(デンマーク)
    • Year and Date
      2012-08-15
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Characterization of stem cells and cancer cells on the basis of gene expression dynamics and robustness2012

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      summer school "DNA dynamics and life strategies"
    • Place of Presentation
      Krogerup Hoejskole(デンマーク)
    • Year and Date
      2012-08-15
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Biological Homeostasis: Adaptation by Catalytic Reaction Networks and Temperature Compensation in Biological Rhythm2012

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Dynamics Days Asia Pacific
    • Place of Presentation
      Academia Sinica(台湾)
    • Year and Date
      2012-08-07
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 学習による自発活動とその刺激に対する応答の形成2012

    • Author(s)
      栗川知己
    • Organizer
      包括脳夏のワークショップ
    • Place of Presentation
      仙台国際センター(仙台)
    • Year and Date
      2012-07-26
    • Related Report
      2012 Annual Research Report
  • [Presentation] Phenotypic fluctuations, developmental Plasticity, and environmental variation2012

    • Author(s)
      K. Kaneko
    • Organizer
      Euro Evo Devo
    • Place of Presentation
      Univ. ofLisbon (Lisbon,ポルトガル)
    • Year and Date
      2012-07-12
    • Related Report
      2013 Final Research Report
  • [Presentation] Phenotypic fluctuations, developmental plasticity, and environmental variation2012

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Euro Evo Devo
    • Place of Presentation
      University of Lisbon(ポルトガル)
    • Year and Date
      2012-07-12
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Direction of Alpha Travelling Wave Associated with Detection of Near-Threshold Stimuli2012

    • Author(s)
      Daisuke SHimaoka
    • Organizer
      Association for Scientific Study of Consciousness
    • Place of Presentation
      サセックス大学(英国)
    • Year and Date
      2012-07-04
    • Related Report
      2012 Annual Research Report
  • [Presentation] Representation of biological plasticity in terms of dynamical systems2012

    • Author(s)
      金子邦彦
    • Organizer
      International Workshop on Anomalous Statistics, Generalized Entropies, and Information Geometry
    • Place of Presentation
      奈良女子大学
    • Year and Date
      2012-03-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evolution of Robustness formulated in terms of Phenotypic Variances2012

    • Author(s)
      K. Kaneko
    • Organizer
      Workshop 3: Robustness in Biological Systems
    • Place of Presentation
      オハイオ(米国)
    • Year and Date
      2012-02-06
    • Related Report
      2013 Final Research Report
  • [Presentation] Evolution of Robustness formulated in terms of Phenotypic Variances2012

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      Workshop 3 : Robustness in Biological Systems
    • Place of Presentation
      オハイオ(米国)(招待講演)
    • Year and Date
      2012-02-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 短期記憶を持つリカレントネットワークの記憶保持と想起のダイナミクス2011

    • Author(s)
      斉藤稔
    • Organizer
      日本物理学会2011年秋季大会
    • Place of Presentation
      富山大学
    • Year and Date
      2011-09-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] inhomogeneous limit cycle2011

    • Author(s)
      後藤佑介
    • Organizer
      日本物理学会2011年秋季大会
    • Place of Presentation
      富山大学
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 適応進化におけるルシャトリエ原理2011

    • Author(s)
      金子邦彦
    • Organizer
      日本物理学会2011年秋季大会
    • Place of Presentation
      富山大学
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Bifurcation-ability from Itinerant Motion Provides Biological Plasticity : Differentiation from Stem Cells and Neural Memory of2011

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      Dynamics Days Europe 2011
    • Place of Presentation
      オルデンブルク(ドイツ)(招待講演)
    • Year and Date
      2011-09-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evolution as a stochastic process2011

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      SMBE 2011
    • Place of Presentation
      京都大学(招待講演)
    • Year and Date
      2011-07-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Complex Systems Biology : exploring the logic of life through consistency principle2011

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      International Conference on Complex Systems 2011
    • Place of Presentation
      ボストン(米国)(招待講演)
    • Year and Date
      2011-06-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Designing plastic and robust systemis through evolution and learning2011

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      The 3rd International Conference on Cognitive Neurodynamics
    • Place of Presentation
      ヒルトンニセコビレッジ
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] "Memories as Bifurcations" : A simple model2011

    • Author(s)
      Tomoki KURIKAWA
    • Organizer
      The 3rd International Conference on Cognitive Neurodynamics
    • Place of Presentation
      ヒルトンニセコビレッジ
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Ongoing global phase pattern and visual signal detection2011

    • Author(s)
      Daisuke SHIMAOKA
    • Organizer
      The 3rd International Conference on Cognitive Neurodynamics
    • Place of Presentation
      ヒルトンニセコビレッジ
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 発生過程の頑健性がつくる発生砂時計モデル2011

    • Author(s)
      鴻巣暁
    • Organizer
      第67会日本物理学会年会
    • Place of Presentation
      関西学院大学
    • Year and Date
      2011-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Characterization of Stem Cells and Cancer Cells on the Basis of Gene Expression Profile Stability and Dynamics2011

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      CDB Symposium "Quantitative Developmental Biology"
    • Place of Presentation
      理化学研究所CDB
    • Year and Date
      2011-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Simple Gene Networks Models Show Cell Differentiation Behavior2011

    • Author(s)
      Yusuke Goto
    • Organizer
      CDB Symposium "Quantitative Developmental Biology"
    • Place of Presentation
      理化学研究所CDB
    • Year and Date
      2011-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evolutionary Process Maintaining the Robustness in Development Conserves the Middle Stage in Development2011

    • Author(s)
      Akira Konosu
    • Organizer
      CDB Symposium "Quantitative Developmental Biology"
    • Place of Presentation
      理化学研究所CDB
    • Year and Date
      2011-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evolution of Pattern Formation2011

    • Author(s)
      Takahiro Kohsokabe
    • Organizer
      CDB Symposium "Quantitative Developmental Biology"
    • Place of Presentation
      理化学研究所CDB
    • Year and Date
      2011-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 連想記憶の学習による自発的脳活動の形成2011

    • Author(s)
      栗川知己
    • Organizer
      第67会日本物理学会年会
    • Place of Presentation
      関西学院大学
    • Year and Date
      2011-03-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 環境適応の進化:揺らぎとルシャトリエ原理2011

    • Author(s)
      金子邦彦
    • Organizer
      第67会日本物理学会年会
    • Place of Presentation
      関西学院大学
    • Year and Date
      2011-03-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 表現型の可塑性を考慮した集団的進化ダイナミクス2011

    • Author(s)
      斉藤稔
    • Organizer
      第67会日本物理学会年会
    • Place of Presentation
      関西学院大学
    • Year and Date
      2011-03-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 表現型可塑性が種分化を促す力学系モデル2011

    • Author(s)
      後藤佑介
    • Organizer
      第67会日本物理学会年会
    • Place of Presentation
      関西学院大学
    • Year and Date
      2011-03-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 遺伝子制御ネットワークによる非周期空間パターン形成の仕組み及びその進化2011

    • Author(s)
      香曽我部隆裕
    • Organizer
      第67会日本物理学会年会
    • Place of Presentation
      関西学院大学
    • Year and Date
      2011-03-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Itinerant Dynamics in Gene Expression Implies Pluripotency2011

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Far-From-Equilibrium Dynamics
    • Place of Presentation
      京都大学
    • Year and Date
      2011-01-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] 学習による分岐構造の形成2010

    • Author(s)
      栗川知己、金子邦彦
    • Organizer
      日本物理学会 平成22年度秋季大会
    • Place of Presentation
      大阪府立大学
    • Year and Date
      2010-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 分岐としての記憶を埋め込むことにより形成される自発的神経活動の構造2010

    • Author(s)
      栗川知己
    • Organizer
      NEURO2010
    • Place of Presentation
      神戸コンベンションセンター
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Itinerant Dynamics in Gene Expression Implies Pluripotency2010

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Biological networks-Principles and Dynamics
    • Place of Presentation
      北京(中国)
    • Year and Date
      2010-07-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Spontaneous dynamics shaped through learning process with multiple timescales2010

    • Author(s)
      栗川知己、金子邦彦
    • Organizer
      脳と心のメカニズム第10回冬のワークショップ
    • Place of Presentation
      北海道・留寿都リゾート
    • Year and Date
      2010-01-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] Tansient cortical activity during Necker cube perception from local clusters to global synchrony.2009

    • Author(s)
      Shimaoka, D., Kitajo, K., Kaneko, K., Yamaguchi, Y.
    • Organizer
      Conference on Consciousness and its Measures
    • Place of Presentation
      リマソル(キプロス)
    • Year and Date
      2009-11-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 多時間スケールをもつ学習モデルとその相空間構造の変化(Learning Model with Multiple timescales and Change in a Structure of Phase Space)2009

    • Author(s)
      Tomoki Kurikawa
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      アスティとくしま
    • Year and Date
      2009-10-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] Evolution of robustness to noise and mutation in gene expression dynamics2009

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Summer School/Workshop on Steps in Evolution
    • Place of Presentation
      ブレーメン(ドイツ)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Change in structure of phase space through learning with multiple timescales.2009

    • Author(s)
      Tomoki Kurikawa, Kunihiko Kaneko
    • Organizer
      International Symposium on Complex Systems Biology
    • Place of Presentation
      東京大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] Macroscopic relationship among robustness, evolvablity, and phenotypic fluctuations2009

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      What is Evolution? Bicentennial of Charles Darwin's Birth
    • Place of Presentation
      Co-op Inn Kyoto Conference Hall
    • Related Report
      2009 Annual Research Report
  • [Presentation] Dynamical-Systems Perspective to Stem-cell Biology:Relevance of oscillatory gene expression dynamics and cell-cell interaction

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Symposium on Systems Biology of Stem Cells
    • Place of Presentation
      Beckman Center (Irvine, California, 米国)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Memories as bifurcations shaped through sequential learning

    • Author(s)
      Tomoki KURIKAWA
    • Organizer
      The 4th International Conference on Cognitive Neurodynamics
    • Place of Presentation
      Agora for Biosystems(Sigtuna, スウェーデン)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Plasticity and Robustness in Evolution: Macroscopic Theory, Model Simulations, and Laboratory Experiments - Part I.

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      Quantitative Laws of Genome Evolution
    • Place of Presentation
      Villa del Grumello(Como, イタリア)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Plasticity and Robustness in Evolution: Macroscopic Theory, Model Simulations, and Laboratory Experiments - Part II.

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      Quantitative Laws of Genome Evolution
    • Place of Presentation
      Villa del Grumello(Como, イタリア)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Complexity in Genotype-Phenotype Mapping Facilitates Evolution of Genetic Redundancy

    • Author(s)
      Nen Saito
    • Organizer
      Quantitative Laws of Genome Evolution
    • Place of Presentation
      Villa del Grumello(Como, イタリア)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 力学系的視座に基づく進化-発生対応の探究

    • Author(s)
      香曽我部隆裕
    • Organizer
      第15回 日本進化学会
    • Place of Presentation
      筑波大学(茨城県つくば市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 遺伝型-表現型マップの複雑性が遺伝的冗長性の進化を促進する

    • Author(s)
      斉藤稔
    • Organizer
      第23回 日本数理生物学会大会
    • Place of Presentation
      静岡大学(静岡県静岡市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] パターン形成力学系の進化に於ける遅い変数の持つ役割

    • Author(s)
      香曽我部貴裕
    • Organizer
      日本物理学会2013年秋季大会
    • Place of Presentation
      徳島大学(徳島県徳島市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] レプリカ法を用いたネットワーク上のチューリングパターンの解析

    • Author(s)
      斉藤稔
    • Organizer
      日本物理学会2013年秋季大会
    • Place of Presentation
      徳島大学(徳島県徳島市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 環境変動と表現型変動を考慮した進化のモデル

    • Author(s)
      斉藤稔
    • Organizer
      日本物理学会2013年秋季大会
    • Place of Presentation
      徳島大学(徳島県徳島市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 少数性転移による反応フロースイッチ機構

    • Author(s)
      斉藤稔
    • Organizer
      研究会「理論と実験」2013
    • Place of Presentation
      広島大学(広島県東広島市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dynamical-Systems view of Plasticity and Robustness: In Development and Evolution

    • Author(s)
      Kunihiko Kaneko
    • Organizer
      Symposium on Complex Biodynamics and Networks
    • Place of Presentation
      慶應義塾大学(山形県鶴岡市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dynamical Systems with Time-scale Interference for a Theory of Biological Plasticity and Robustness

    • Author(s)
      金子邦彦
    • Organizer
      The 3rd International Symposium on Innovative Mathematical Modelling
    • Place of Presentation
      東京大学、生産技術研究所(東京都目黒区)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 少数性転移による反応フロースイッチ

    • Author(s)
      斉藤稔
    • Organizer
      定量生物学の会 第六回年会
    • Place of Presentation
      大阪大学(大阪府吹田市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dynamical systems theory for robustness and plasticity in cell differentiation

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      Workshop on “Complex Systems Theory and Cancer Biology
    • Place of Presentation
      the Tempe Mission Palms Resort Hotel (Tempe, Arizona, 米国)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Autonomous regulation of biological time by catalytic reaction dynamics

    • Author(s)
      Kunihiko KANEKO
    • Organizer
      Beyond Centre Workshop on the Physics of Living Matter
    • Place of Presentation
      the Tempe Mission Palms Resort Hotel (Tempe, Arizona, 米国)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 多時間スケールの階層構造を持つリカレントニューラルネットワークの学習則

    • Author(s)
      松元叡一
    • Organizer
      日本物理学会 第69回年次大会
    • Place of Presentation
      東海大学(神奈川県平塚市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 分岐から見る進化 発生対応とその崩れ

    • Author(s)
      香曽我部隆裕
    • Organizer
      日本物理学会 第69回年次大会
    • Place of Presentation
      東海大学(神奈川県平塚市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 定常成長細胞のマクロ現象論:全成分にわたる共通応答関係

    • Author(s)
      金子邦彦
    • Organizer
      日本物理学会 第69回年次大会
    • Place of Presentation
      東海大学(神奈川県平塚市)
    • Related Report
      2013 Annual Research Report
  • [Book] Advances in Cognitive Neurodynamics III ("Memories as Bifurcations": A Simple Model.)2013

    • Author(s)
      Tomoki Kurikawa and Kunihiko Kaneko
    • Total Pages
      600
    • Publisher
      Springer
    • Related Report
      2013 Annual Research Report
  • [Book] Advances in Cognitive Neurodynamics III (Ongoing Global Phase Pattern and Visual Signal Detection.)2013

    • Author(s)
      Daisuke Shimaoka, Keiichi Kitajo, Kunihiko Kaneko, Yoko Yamaguchi
    • Total Pages
      600
    • Publisher
      Springer
    • Related Report
      2013 Annual Research Report
  • [Book] Advances in Cognitive Neurodynamics III (Balancing Robustness with Plasticity Through Evolution and Learning)2013

    • Author(s)
      Kunihiko Kaneko
    • Total Pages
      600
    • Publisher
      Springer
    • Related Report
      2013 Annual Research Report
  • [Book] "Phenotypic Plasticity and Robustness : Evolutionary Stability Theory, Gene Expression Dynamics Model, and Laboratory Experiments "Evolutionary Systems Biology2012

    • Author(s)
      K. Kaneko(ed. O. Soyer)
    • Publisher
      Springer
    • Related Report
      2013 Final Research Report

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Published: 2009-04-01   Modified: 2018-03-28  

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