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大集団科学による個体ー世界相互作用に基づく人間の当事者化のリアルワールド実証

Planned Research

Project AreaHuman behavioral science for subjectification ("tojisha-ka") by interaction-based & rule-/story-based understanding of the brain & the world
Project/Area Number 21H05173
Research Category

Grant-in-Aid for Transformative Research Areas (A)

Allocation TypeSingle-year Grants
Review Section Transformative Research Areas, Section (I)
Research InstitutionTokyo Metropolitan Institute of Medical Science

Principal Investigator

西田 淳志  公益財団法人東京都医学総合研究所, 社会健康医学研究センター, 社会健康医学研究センター長 (20510598)

Co-Investigator(Kenkyū-buntansha) 村井 俊哉  京都大学, 医学研究科, 教授 (30335286)
永澤 美保  麻布大学, 獣医学部, 准教授 (70533082)
Project Period (FY) 2021-09-10 – 2026-03-31
Project Status Granted (Fiscal Year 2025)
Budget Amount *help
¥333,060,000 (Direct Cost: ¥256,200,000、Indirect Cost: ¥76,860,000)
Fiscal Year 2025: ¥63,830,000 (Direct Cost: ¥49,100,000、Indirect Cost: ¥14,730,000)
Fiscal Year 2024: ¥62,920,000 (Direct Cost: ¥48,400,000、Indirect Cost: ¥14,520,000)
Fiscal Year 2023: ¥63,310,000 (Direct Cost: ¥48,700,000、Indirect Cost: ¥14,610,000)
Fiscal Year 2022: ¥63,180,000 (Direct Cost: ¥48,600,000、Indirect Cost: ¥14,580,000)
Fiscal Year 2021: ¥79,820,000 (Direct Cost: ¥61,400,000、Indirect Cost: ¥18,420,000)
Keywords思春期 / コホート / 当事者化 / 個体‐世界相互作用 / マイノリティ / 脳行動スパイラル / 社会モデル / 個体ー世界相互作用 / 大集団科学 / 個体-世界相互作用 / 個体・世界相互作用 / 思春期コホート / リアルワールド / 価値
Outline of Research at the Start

「大集団科学による個体‐世界相互作用に基づく人間の当事者化のリアルワールド実証」(略称:リアルワールド実証チーム)では、思春期に人間が世界との相互作用の中で「当事者化」していく過程とその機構、およびその長期的生涯影響について、大規模思春期コホート(N=3000)である「東京ティーンコホート」等を用いて実証的に明らかにする。ライフコース疫学者、精神医学・脳科学者、動物行動学者の密な連携によって、東京という国際的大都市において、COVID-19の大流行時代に若者が当事者としてどう世界にコミットしているのか、というリアルで切実な主題を個体-世界相互作用の観点から明らかにする。

Outline of Annual Research Achievements

「大集団科学による個体‐世界相互作用に基づく人間の当事者化のリアルワールド実証」(略称:リアルワールド実証チーム)では、思春期に人間が世界との相互作用の中で「当事者化」していく過程とその機構を明らかにすべく、引き続き「東京ティーンコホート」等の大規模調査によるデータ収集を進め、すでに収集済のデータを使用して予備的な解析を行った。領域全体での「当事者化」のコンセプトや定義、さらには「社会モデル」に関する活発な議論を踏まえて、計画班内で共通に導入した測定指標データを中心に予備解析を実施した。自らのマイノリティ性を感じている若者たちの中にも、自尊心やウェルビーイング(精神的幸福感)などが高いグループと低いグループがあり、それらを分岐させる複数の社会的要因を見出した(弱音を吐ける他者との繋がり、良い学校風土など)。思春期に妊娠・出産を経験している女性とその子供を対象としたコホート調査では、妊娠までのライフコースにおいて虐待や経済的困窮などの逆境を経験してきた女性たちが、妊娠を機に信頼できる支援者と出会い、交流を深めるプロセスのなかでウェルビーイングが回復していくことを確認した(Baba & Yamasaki et al., in submission)。高校生・大学生を対象としたオンライン調査データの分析を進め、思春期女子群において、イヌネコ飼育が家族との関わりを通してウェルビーイングを高め、マイノリティ感を低下させることも見出している(Koyasu et al., 2023)。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

新型コロナの感染拡大により開始や進捗がやや遅れていた思春期コホート調査は、新型コロナの5類移行後、その進捗ペースが早まり、当初の遅れを取り戻しているため、おおむね順調に進展していると判断した。

Strategy for Future Research Activity

思春期コホート調査、若年母子コホート、脳画像研究等、現在進めている大規模調査を完了に向けて進め、最終データセットを構築し、データ解析を本格化する。特に、計画班内の様々な調査に共通して導入した当事者化に関する指標とその関連要因の解析を進める。また、英国の思春期コホートとの比較研究をさらに進め、マイノリティ性を感じている若者のwell-beingに影響を与える社会要因とその日英比較についての研究を進める。

Report

(3 results)
  • 2023 Annual Research Report
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • Research Products

    (35 results)

All 2024 2023 2022 2021 Other

All Int'l Joint Research (6 results) Journal Article (21 results) (of which Int'l Joint Research: 13 results,  Peer Reviewed: 21 results,  Open Access: 19 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results) Remarks (3 results) Funded Workshop (2 results)

  • [Int'l Joint Research] King's College London/University College London/University of Bristol(英国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] New York University/Harvard Medical School(米国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] King's College London/University College London/University of Bristol(英国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] New York University(米国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Fordham University(米国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] King's College of London/University College London/University of Bristol(英国)

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Suicidal Thoughts and Trajectories of Psychopathological and Behavioral Symptoms in Adolescence.2024

    • Author(s)
      Uno A, Nagaoka D, Usami S, Yamaguchi S, Minami R, Tanaka R, Sawai Y, Okuma A, Yamasaki S, Miyashita M, Nishida A, Kasai K, Ando S.
    • Journal Title

      JAMA Network Open

      Volume: 7 Issue: 1 Pages: e2353166-e2353166

    • DOI

      10.1001/jamanetworkopen.2023.53166

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Longitudinal Relationships Between Help-Seeking Intentions and Depressive Symptoms in Adolescents2023

    • Author(s)
      Satoshi Yamaguchi, Shuntaro Ando, Mitsuhiro Miyashita, Satoshi Usami, Syudo Yamasaki, Kaori Endo, Jordan DeVylder, Daniel Stanyon, Kaori Baba, Naomi Nakajima, Junko Nimura, Miharu Nakanishi, Mariko Hiraiwa-Hasegawa, Kiyoto Kasai, Atsushi Nishida
    • Journal Title

      Journal of adolescent health

      Volume: 73(6) Issue: 6 Pages: 1061-1067

    • DOI

      10.1016/j.jadohealth.2023.06.033

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association between menopause and suicidal ideation in mothers of adolescents: A longitudinal study using data from a population-based cohort2023

    • Author(s)
      Nakanishi M, Endo K, Yamasaki S, Stanyon D, Sullivan S, Yamaguchi S, Ando S, Hiraiwa-Hasegawa M, Kasai K, Nishida A, Miyashita M.
    • Journal Title

      Journal of Affective Disorders.

      Volume: 340 Pages: 529-534

    • DOI

      10.1016/j.jad.2023.08.055

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Informal Caregiving in Adolescents from 10 to 16 Years Old: A Longitudinal Study Using Data from the Tokyo Teen Cohort2023

    • Author(s)
      Nakanishi M, Stanyon D, Richards M, Yamasaki S, Ando S, Endo K, Hosozawa M, Miyashita M, Hiraiwa-Hasegawa M, Kasai K, Nishida A.
    • Journal Title

      Internatinal Journal of Environment Research and Public Health.

      Volume: 20(15) Issue: 15 Pages: 6482-6482

    • DOI

      10.3390/ijerph20156482

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identify adolescents' help-seeking intention on suicide through self- and caregiver's assessments of psychobehavioral problems: deep clustering of the Tokyo TEEN Cohort study2023

    • Author(s)
      Nagaoka D, Uno A, Usami S, Tanaka R, Minami R, Sawai Y, Okuma A, Yamasaki S, Miyashita M, Nishida A, Kasai K, Ando S.
    • Journal Title

      Lancet Reg Health West Pac.

      Volume: 43 Pages: 100979-100979

    • DOI

      10.1016/j.lanwpc.2023.100979

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ownership of dogs and cats leads to higher levels of well-being and general trust through family involvement in late adolescence2023

    • Author(s)
      Hikari Koyasu, Sakura Ogasawara, Takefumi Kikusui & Miho Nagasawa
    • Journal Title

      Frontiers in Veterinary Science

      Volume: 10 Pages: 1220265-1220265

    • DOI

      10.3389/fvets.2023.1220265

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of the COVID-19 Pandemic on the Behavioural Tendencies of Cats and Dogs in Japan2023

    • Author(s)
      Takagi Saho、Koyasu Hikari、Hattori Madoka、Nagasawa Takumi、Maejima Michiro、Nagasawa Miho、Kikusui Takefumi、Saito Atsuko
    • Journal Title

      Animals

      Volume: 13 Issue: 13 Pages: 2217-2217

    • DOI

      10.3390/ani13132217

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The eleven-item Alcohol, Smoking and Substance Involvement Screening Test (ASSIST-11): Cross-cultural psychometric evaluation across 42 countries2023

    • Author(s)
      Lee CT, Lin CY, Fujirewa H et al
    • Journal Title

      Journal of Psychiatric Research

      Volume: 165 Pages: 16-27

    • DOI

      10.1016/j.jpsychires.2023.06.033

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Psychometric properties of the Alcohol Use Disorders Identification Test (AUDIT) across cross-cultural subgroups, genders, and sexual orientations: Findings from the International Sex Survey (ISS)2023

    • Author(s)
      Horvath Z, Fujiwara H et al
    • Journal Title

      Comprehensive Psychiatry

      Volume: 127 Pages: 1-23

    • DOI

      10.1016/j.comppsych.2023.152427

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Attributes of auditory hallucinations associated with self-harm: a prospective cohort study2023

    • Author(s)
      DeVylder J, Yamasaki S, Ando S, Miyashita M, Endo ., Baba K, Niimura J, Nakajima N, Yamaguchi S, Stanyon D, Narita Z, Schiffman J, Hiraiwa-Hasegawa M, Kasai K, Nishida A
    • Journal Title

      Schizophr Res

      Volume: 251 Pages: 30-36

    • DOI

      10.1016/j.schres.2022.12.008

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ethnoracial Variation in Risk for Psychotic Experiences2023

    • Author(s)
      DeVylder J, Anglin D, Munson MR, Nishida A, Oh H, Marsh J, Narita Z, Bareis N, Fedina L.
    • Journal Title

      Schizophrenia Bulletin.

      Volume: 49(2) Issue: 2 Pages: 385-396

    • DOI

      10.1093/schbul/sbac171

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Predictors of chronic loneliness during adolescence: a population-based cohort study2022

    • Author(s)
      Hosozawa Mariko、Cable Noriko、Yamasaki Syudo、Ando Shuntaro、Endo Kaori、Usami Satoshi、Nakanishi Miharu、Niimura Junko、Nakajima Naomi、Baba Kaori、Oikawa Nao、Stanyon Daniel、Suzuki Kazuhiro、Miyashita Mitsuhiro、Iso Hiroyasu、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
    • Journal Title

      Child and Adolescent Psychiatry and Mental Health

      Volume: 16 Issue: 1

    • DOI

      10.1186/s13034-022-00545-z

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Auditory Hallucinations and Self-Injurious Behavior in General Population Adolescents: Modeling Within-Person Effects in the Tokyo Teen Cohort2022

    • Author(s)
      Stanyon Daniel、DeVylder Jordan、Yamasaki Syudo、Yamaguchi Satoshi、Ando Shuntaro、Usami Satoshi、Endo Kaori、Miyashita Mitsuhiro、Kanata Sho、Morimoto Yuko、Hosozawa Mariko、Baba Kaori、Nakajima Naomi、Niimura Junko、Nakanishi Miharu、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
    • Journal Title

      Schizophrenia Bulletin

      Volume: 49 Issue: 2 Pages: 329

    • DOI

      10.1093/schbul/sbac155

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Maternal parenting stress from birth to 36months, maternal depressive symptoms, and physical punishment to 10-year-old children: a population-based birth cohort study2022

    • Author(s)
      Niimura Junko、Nakanishi Miharu、Yamasaki Syudo、Ando Shuntaro、Kanata Sho、Fujikawa Shinya、Morimoto Yuko、Endo Kaori、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
    • Journal Title

      Social Psychiatry and Psychiatric Epidemiology

      Volume: 57 Issue: 11 Pages: 2207

    • DOI

      10.1007/s00127-022-02319-6

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The role of bullying victimization in the pathway between autistic traits and psychotic experiences in adolescence: Data from the Tokyo Teen Cohort study2022

    • Author(s)
      Stanyon Daniel、Yamasaki Syudo、Ando Shuntaro、Endo Kaori、Nakanishi Miharu、Kiyono Tomoki、Hosozawa Mariko、Kanata Sho、Fujikawa Shinya、Morimoto Yuko、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
    • Journal Title

      Schizophrenia Research

      Volume: 239 Pages: 111

    • DOI

      10.1016/j.schres.2021.11.015

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Psychotic experiences predict subsequent loneliness among adolescents: A population-based birth cohort study2022

    • Author(s)
      Endo Kaori、Yamasaki Syudo、Nakanishi Miharu、DeVylder Jordan、Usami Satoshi、Morimoto Yuko、Stanyon Daniel、Suzuki Kazuhiro、Miyashita Mitsuhiro、Arai Makoto、Fujikawa Shinya、Kanata Sho、Ando Shuntaro、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
    • Journal Title

      Schizophrenia Research

      Volume: 239 Pages: 123

    • DOI

      10.1016/j.schres.2021.11.031

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Migration and psychotic experiences in the Tokyo Teen Cohort2022

    • Author(s)
      DeVylder Jordan、Endo Kaori、Yamasaki Syudo、Ando Shuntaro、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
    • Journal Title

      Journal of Migration and Health

      Volume: 5 Pages: 100078-100078

    • DOI

      10.1016/j.jmh.2022.100078

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Life habits and mental health: behavioural addiction, health benefits of daily habits, and the reward system.2022

    • Author(s)
      *Fujiwara H, Tsurumi K, Shibata M, Kobayashi K, Miyagi T, Ueno T, Oishi N, Murai T.
    • Journal Title

      Front. Psychiatry.

      Volume: 27 Pages: 813507-813507

    • DOI

      10.3389/fpsyt.2022.813507

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Japanese version of the Generalized Problematic Internet Use Scale 2 (GPIUS2): Psychometric evaluation and analysis of the theoretical model2022

    • Author(s)
      Yoshimura Sayaka、Shibata Mami、Kyuragi Yusuke、Kobayashi Kei、Aki Morio、Murai Toshiya、Fujiwara Hironobu
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 11 Pages: e0273895-e0273895

    • DOI

      10.1371/journal.pone.0273895

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Lower help-seeking intentions mediate subsequent depressive symptoms among adolescents with high autistic traits: a population-based cohort study2021

    • Author(s)
      Hosozawa Mariko、Yamasaki Syudo、Ando Shuntaro、Endo Kaori、Morimoto Yuko、Kanata Sho、Fujikawa Shinya、Cable Noriko、Iso Hiroyasu、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
    • Journal Title

      European Child and Adolescent Psychiatry

      Volume: 32 Issue: 4 Pages: 621

    • DOI

      10.1007/s00787-021-01895-3

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Structural brain changes in severe and enduring anorexia nervosa: A multimodal magnetic resonance imaging study of gray matter volume, cortical thickness, and white matter integrity2021

    • Author(s)
      Mishima Ryo、Isobe Masanori、Noda Tomomi、Tose Keima、Kawabata Michiko、Noma Shun'ichi、Murai Toshiya
    • Journal Title

      Psychiatry Research: Neuroimaging

      Volume: 318 Pages: 111393-111393

    • DOI

      10.1016/j.pscychresns.2021.111393

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Presentation] Longitudinal Relationships Between Help-Seeking Intentions and Depressive Symptoms in Adolescents2023

    • Author(s)
      Miyashita M, Nishida A
    • Organizer
      Children of the noughties: a conference to celebrate 21 years of the Millennium Cohort Study (London)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ライフコースアプローチによる心の健康づくり. 日・英大規模出生コホート研究の経験から.2022

    • Author(s)
      西田 淳志
    • Organizer
      第19回日本うつ病学会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] イヌはなぜ ヒトの「最良の友」になったのか2022

    • Author(s)
      永澤 美保
    • Organizer
      第46回日本比較内分泌学会大会
    • Related Report
      2022 Annual Research Report
  • [Remarks] 東京ティーンコホート

    • URL

      http://ttcp.umin.jp/

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report 2021 Annual Research Report
  • [Remarks] REACH cohort

    • URL

      https://www.thereachstudy.com/

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report
  • [Remarks] 東京都医学総合研究所社会健康医学研究センター

    • URL

      https://mentalhealth-unit.jp/

    • Related Report
      2021 Annual Research Report
  • [Funded Workshop] Social Determinants of Mental Health 20242024

    • Related Report
      2023 Annual Research Report
  • [Funded Workshop] Early Detection and Social Intervention for Psychosis and Suicide2023

    • Related Report
      2022 Annual Research Report

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Published: 2021-10-22   Modified: 2025-06-20  

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