| Budget Amount *help |
¥54,080,000 (Direct Cost: ¥41,600,000、Indirect Cost: ¥12,480,000)
Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2012: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2011: ¥20,800,000 (Direct Cost: ¥16,000,000、Indirect Cost: ¥4,800,000)
Fiscal Year 2010: ¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
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| Outline of Final Research Achievements |
Novel elastin-like polypeptides have been developed as control molecules for the creation of fusion materials. The polypeptides consist of several functional blocks, the design of which was inspired by the domain structure of native elastin. The polypeptides form well-defined nanofibers in aqueous solution by external stimuli. The silver-binding sequence was fused to the elastin-like polypeptide to give silver nanoparticle-polypeptide nanofiber composite materials that show anti-bacterial properties. Hybrid scaffold was fabricated from the polypeptide fiber and a biocompatible polymer. As a collaborative research in the project, polymer-mediated self-assembly of inorganic nanoparticles was conducted. Unique ring-like nanostructure of silica nanoparticles was obtained in the liquid phase by using synthetic block copolymer as a mediator.
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