|Budget Amount *help
¥95,810,000 (Direct Cost : ¥73,700,000、Indirect Cost : ¥22,110,000)
Fiscal Year 2014 : ¥15,470,000 (Direct Cost : ¥11,900,000、Indirect Cost : ¥3,570,000)
Fiscal Year 2013 : ¥16,250,000 (Direct Cost : ¥12,500,000、Indirect Cost : ¥3,750,000)
Fiscal Year 2012 : ¥21,320,000 (Direct Cost : ¥16,400,000、Indirect Cost : ¥4,920,000)
Fiscal Year 2011 : ¥21,060,000 (Direct Cost : ¥16,200,000、Indirect Cost : ¥4,860,000)
Fiscal Year 2010 : ¥21,710,000 (Direct Cost : ¥16,700,000、Indirect Cost : ¥5,010,000)
|Outline of Final Research Achievements
In this research area, we have developed neuro-imaging, gene-knock-in in human iPSCs, and rapid neuro-differentiation technologies. Using these technologies, we generated and analyzed ALS motor neurons and found novel pathogenesis (Sci Transl Med 2012). Also, we generated cortical neurons and astrocytes from Alzheimer’s patients, and found a new direction of medicine (Cell Stem Cell 2013). Furthermore, we showed the potential of human iPSCs as a cellular resource for ALS transplantation therapy (Stem Cell Reports 2014).
We have promoted collaborative works with other members in this area by sharing our technology.