| Budget Amount *help |
¥72,410,000 (Direct Cost: ¥55,700,000、Indirect Cost: ¥16,710,000)
Fiscal Year 2014: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Fiscal Year 2013: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2012: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2011: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2010: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
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| Outline of Final Research Achievements |
We developed a 3D image registration method and a super-resolution method, and applied them to detection of synaptic structure changes during mice motor learning. We also developed a functional connectivity analysis method to identify rats’ neuron-neuron or neuron-glia networks based on functional multi-neuron calcium imaging. We found firing rate of neighboring neurons was elevated after glial activities increased. Similar functional connectivity analysis was performed on calcium imaging on fly larvae motor circuits, and we found there were neural clusters which exhibited different activity phases within larvae motor behaviors.
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