• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Comprehensive analysis of lysophospholipids using model animals

Planned Research

Project AreaMachineries of bioactive lipids in homeostasis and diseases
Project/Area Number 22116004
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionTohoku University

Principal Investigator

AOKI Junken  東北大学, 薬学研究科(研究院), 教授 (20250219)

Project Period (FY) 2010-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥127,790,000 (Direct Cost: ¥98,300,000、Indirect Cost: ¥29,490,000)
Fiscal Year 2014: ¥21,190,000 (Direct Cost: ¥16,300,000、Indirect Cost: ¥4,890,000)
Fiscal Year 2013: ¥22,490,000 (Direct Cost: ¥17,300,000、Indirect Cost: ¥5,190,000)
Fiscal Year 2012: ¥26,650,000 (Direct Cost: ¥20,500,000、Indirect Cost: ¥6,150,000)
Fiscal Year 2011: ¥24,830,000 (Direct Cost: ¥19,100,000、Indirect Cost: ¥5,730,000)
Fiscal Year 2010: ¥32,630,000 (Direct Cost: ¥25,100,000、Indirect Cost: ¥7,530,000)
Keywordsリゾリン脂質 / GPCR / 産生酵素 / マウス / ゼブラフィッシュ / リゾホスファチジン酸 / LPA受容体 / 血管形成 / TALEN / リン脂質 / モデル生物 / マススペクトロメトリー / メディエーター / 受容体 / 質量分析機器
Outline of Final Research Achievements

Lysophospholipids are phospholipids that have only one acy chains. In the past two decades many GPCRs have been shown to react specifically with some of lysophospholipids. These include receptor for lysophosphatidic acid (LPA) and sphingosine 1 phosphate (S1P). In addition, specific enzymes that produce these lysophosphspholipids have been identified. Interestingly, these receptors and synthetic enzymes for lysophospholipids are highly conserved in vertebrates. Thus, in this study, to identify the patho-physiological roles of lysophospholipids, which is conserved among the wide range of vertebrates, we performed functional analyses of lysophospholipid receptors and synthetic enzymes using zebrafishes and mice as animal models. As one of the results in this study, we found new molecular mechanism underlining the embryonic blood formation mediated by LPA-degrading enzyme.

Report

(6 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (133 results)

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article (32 results) (of which Peer Reviewed: 32 results,  Open Access: 2 results,  Acknowledgement Compliant: 3 results) Presentation (100 results) (of which Invited: 8 results) Remarks (1 results)

  • [Journal Article] Possible involvement of minor lysophospholipids in the increase in plasma lysophosphatidic acid in acute coronary syndrome2015

    • Author(s)
      Kurano M, Suzuki A, Inoue A, Tokuhara Y, Kano K, Matsumoto H, Igarashi K, Ohkawa R, Nakamura K, Dohi T, Miyauchi K, Daida H, Tsukamoto K, Ikeda H, Aoki J, Yatomi Y
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 35 Issue: 2 Pages: 463

    • DOI

      10.1161/atvbaha.114.304748

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo2014

    • Author(s)
      Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J
    • Journal Title

      J. Biochem

      Volume: 155 Issue: 4 Pages: 235

    • DOI

      10.1093/jb/mvt114

    • NAID

      40020035029

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin.2014

    • Author(s)
      Shimizu Y, Morikawa Y, Okudaira S, Kimoto S, Tanaka T, Aoki J, Tokumura A.
    • Journal Title

      Am. J. Pathol.

      Volume: 184 Issue: 5 Pages: 1593-1603

    • DOI

      10.1016/j.ajpath.2014.01.029

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Novel lysophosphoplipid receptors: their structure and function.2014

    • Author(s)
      Makide K, Uwamizu A, Shinjo Y, Ishiguro J, Okutani M, Inoue A, Aoki J.
    • Journal Title

      J. Lipid Res.

      Volume: 55 Issue: 10 Pages: 1986-95

    • DOI

      10.1194/jlr.r046920

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] ENPP2 contributes to adipose tissue expansion and insulin resistance in diet-induced obesity.2014

    • Author(s)
      Nishimura S, Nagasaki M, Okudaira S, Aoki J, Ohmori T, Ohkawa R, Nakamura K, Igarashi K, Yamashita H, Eto K, Uno K, Hayashi N, Kadowaki T, Komuro I, Yatomi Y, Nagai R.
    • Journal Title

      Diabetes

      Volume: 63 Issue: 12 Pages: 4154-4164

    • DOI

      10.2337/db13-1694

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function2013

    • Author(s)
      Nakamura A, Ebina-Shibuya R, Itoh-Nakadai A, Muto A, Shima H, Saigusa D, Aoki J, Ebina M, Nukiwa T, Igarashi K.
    • Journal Title

      J Exp Med.

      Volume: 210 Issue: 11 Pages: 2191

    • DOI

      10.1084/jem.20130028

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TGFα shedding assay: An accurate and versatile method for detecting GPCR activation2012

    • Author(s)
      Asuka Inoue
    • Journal Title

      Nat Methods

      Volume: 9 Issue: 10 Pages: 1021

    • DOI

      10.1038/nmeth.2172

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The β9 Loop Domain of PA-PLA(1)α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis2012

    • Author(s)
      Shinkuma S, Inoue A, Aoki J, Nishie W, Natsuga K, Ujiie H, Nomura T, Abe R, Akiyama M, Shimizu H
    • Journal Title

      The Journal of Investigative Dermatology

      Volume: (印刷中) Issue: 8 Pages: 2093-2095

    • DOI

      10.1038/jid.2012.96

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice2012

    • Author(s)
      Fukuhara S, et al
    • Journal Title

      J Clin Invest

      Volume: (In press)(未定) Issue: 4 Pages: 1416-1426

    • DOI

      10.1172/jci60746

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position2012

    • Author(s)
      Kitamura H, Makide K, Shuto A, Ikubo M, Inoue A, Suzuki K, Sato Y, Nakamura S, Otani Y, Ohwada T, Aoki J
    • Journal Title

      J Biochem

      Volume: 151 Issue: 5 Pages: 511-518

    • DOI

      10.1093/jb/mvs011

    • NAID

      10031166091

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surface loops of extracellular phospholipase A(1) determine both substrate specificity and preference for lysophospholipids2012

    • Author(s)
      Arima N, Inoue A., et al
    • Journal Title

      J Lipid Res

      Volume: 53 Issue: 3 Pages: 513-521

    • DOI

      10.1194/jlr.m022400

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of peroxisomal lipid metabolism by catalytic activity of tumor suppressor H-rev1072012

    • Author(s)
      Uyama T, Ichi I, Kono N, Inoue A, Tsuboi K, Jin XH, Araki N, Aoki J, Arai H, Ueda N
    • Journal Title

      J Biol Chem

      Volume: 287 Issue: 4 Pages: 2706

    • DOI

      10.1074/jbc.m111.267575

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification and biochemical characterization of a novel autotaxin isoform, ATXδ, with a four-amino acid deletion2012

    • Author(s)
      Hashimoto T, Okudaira S, Igarashi K, Hama K, Yatomi Y, Aoki J
    • Journal Title

      J Biochem

      Volume: 151 Issue: 1 Pages: 89

    • DOI

      10.1093/jb/mvr126

    • NAID

      10031166046

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish2011

    • Author(s)
      Yukiura H, Hama K, Nakanaga K, Tanaka M, Asaoka Y, Okudaira S, Arima N, Inoue A, Hashimoto T, Arai H, Kawahara A, Nishina H, Aoki J
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 51 Pages: 43972

    • DOI

      10.1074/jbc.m111.301093

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] LPA-producing enzyme PA-PLA <sub>1</sub> α regulates hair follicle development by modulating EGFR signalling2011

    • Author(s)
      Inoue A., Arima N., et al
    • Journal Title

      EMBO J

      Volume: 30 Issue: 20 Pages: 4248

    • DOI

      10.1038/emboj.2011.296

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Serum autotaxin measurements in pregnant women : application for the differentiation of normal pregnancy and pregnancy-induced hypertension2011

    • Author(s)
      Masuda A, Fujii T, Iwasawa Y, Nakamura K, Ohkawa R, Igarashi K, Okudaira S, Ikeda H, Kozuma S, Aoki J, Yatomi Y
    • Journal Title

      Clin Chim Acta

      Volume: 412 Issue: 21-22 Pages: 1944-1950

    • DOI

      10.1016/j.cca.2011.06.039

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Specific increase in serum autotaxin activity in patients with pancreatic cancer2011

    • Author(s)
      Nakai Y, Ikeda H, Nakamura K, Kume Y, Fujishiro M, Sasahira N, Hirano K, Isayama H, Tada M, Kawabe T, Komatsu Y, Omata M, Aoki J, Koike K, Yatomi Y
    • Journal Title

      Clin Biochem

      Volume: 44 Issue: 8-9 Pages: 576-581

    • DOI

      10.1016/j.clinbiochem.2011.03.128

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autotaxin as a novel serum marker of liver fibrosis2011

    • Author(s)
      Nakagawa H, Ikeda H, Nakamura K, Ohkawa R, Masuzaki R, Tateishi R, Yoshida H, Watanabe N, Tejima K, Kume Y, Iwai T, Suzuki A, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Omata M, Igarashi K, Aoki J, Koike K, Yatomi Y
    • Journal Title

      Clin Chim Acta

      Volume: 412 Issue: 13-14 Pages: 1201-1206

    • DOI

      10.1016/j.cca.2011.03.014

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystal structure of autotaxin and insight into GPCR activation by lipid mediators2011

    • Author(s)
      Nishimasu H, et al
    • Journal Title

      Nat Struct Mol Biol

      Volume: 18 Pages: 205-212

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphati dylcholine2010

    • Author(s)
      Nagai J, et al
    • Journal Title

      Mol Pain

      Volume: 9 Pages: 78-78

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of an activity-based probe for autotaxin2010

    • Author(s)
      Cavalli S, et al
    • Journal Title

      Chembiochem

      Volume: 11 Pages: 2311-2317

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autotaxin controls caudal diencephalon-mesencephalon development in the chick2010

    • Author(s)
      Ohuchi H, et al
    • Journal Title

      Dev Dyn

      Volume: 239 Pages: 2647-2658

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunohistochemical Detection of Autotaxin (ATX)/Lysophospholipase D (lysoPLD) in Submucosal Invasive Colorectal Cancer2010

    • Author(s)
      Kazama S, et al
    • Journal Title

      J Gastrointest Cancer

      Volume: (Epub ahead)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of phosphatidylserine-specific phospholipase A(1) mRNA in human THP-1-derived macrophages2010

    • Author(s)
      Hosono H, et al
    • Journal Title

      Cell Transplant

      Volume: 19 Pages: 759-764

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Glucagon regulates intracellular distribution of adipose differentiation-related protein during triacylglycerol accumulation in the liver2010

    • Author(s)
      Takahashi K, et al
    • Journal Title

      J Lipid Res

      Volume: 51 Pages: 2571-2580

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autotaxin--an LPA producing enzyme with diverse functions2010

    • Author(s)
      Nakanaga K, et al
    • Journal Title

      J Biochem

      Volume: 148 Pages: 13-24

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biological roles of lysophosphatidic acid signaling through its production by autotaxin2010

    • Author(s)
      Okudaira S, et al
    • Journal Title

      Biochimie

      Volume: 92 Pages: 698-706

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid2010

    • Author(s)
      Hama K, et al
    • Journal Title

      Prog Lipid Res

      Volume: 49 Pages: 335-342

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis2010

    • Author(s)
      Shinkuma S, et al
    • Journal Title

      Hum Mutat

      Volume: 31 Pages: 602-610

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A(1) in human serum samples2010

    • Author(s)
      Nakamura K, et al
    • Journal Title

      Clin Chim Acta

      Volume: 411 Pages: 1090-1094

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evidence for De Novo Synthesis of Lysophosphatidic Acid in the Spinal Cord through Phospholipase A2 and Autotaxin in Nerve Injury-induced Neuropathic Pain2010

    • Author(s)
      Ma L, et al
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 333 Pages: 540-546

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts2010

    • Author(s)
      David M, et al
    • Journal Title

      PLoS One

      Volume: 5

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Novel Receptors for lysophosphatidylserine; their structure and function2014

    • Author(s)
      Junken Aoki
    • Organizer
      FEPS2014 (Federation of European Physiological Societies 2014)
    • Place of Presentation
      Budapest (ハンガリー)
    • Year and Date
      2014-08-26 – 2014-08-29
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] LPA3を介する迷走神経機能の解明2014

    • Author(s)
      可野 邦行、青木 淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-06 – 2014-06-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] LPP3 maintains vascular stability by negatively regulating LPA signal2014

    • Author(s)
      Junken Aoki, Hiroshi Yukiura, Kuniyuki Kano, Asuka Inoue
    • Organizer
      18th International Vascular Biology Meeting
    • Place of Presentation
      京都
    • Year and Date
      2014-04-14 – 2014-04-17
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 免疫系を制御する新たな脂質メディエーターリゾホスファチジルセリン2014

    • Author(s)
      青木淳賢
    • Organizer
      日本薬学会
    • Place of Presentation
      熊本
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 酸化リン脂質を認識するGタンパク質共役型受容体2013

    • Author(s)
      井上飛鳥
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      松島
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] New function of LPA3 receptor that regulates vagal afferent nerves activation2013

    • Author(s)
      可野邦行
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 新しいGPCR活性化測定法TGFα切断アッセイ2013

    • Author(s)
      青木淳賢
    • Organizer
      CBI学会年会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Lysophosphatidic acid in blood regulates vagal afferent nerves through LPA3 receptor2013

    • Author(s)
      Junken Aoki
    • Organizer
      FASEB SUMMER RESEARCH CONFERENCE
    • Place of Presentation
      Niseko, Hokkaido
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] アカデミック発創薬:東北大学の試み2012

    • Author(s)
      青木淳賢
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌(招待講演)
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸受容体LPA3の迷走神経を介した心・呼吸抑制作用の解析2012

    • Author(s)
      可野邦行
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたLPAシグナリングの骨形成シグナリングにおける機能解析2012

    • Author(s)
      有馬直明
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 生体内におけるリゾホスファチジルセリンの検出2012

    • Author(s)
      奥谷倫世
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血管形成におけるLPAシグナル調節機構の解析2012

    • Author(s)
      雪浦弘志, 他
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸の血管透過性亢進作用メカニズムの解明2012

    • Author(s)
      近藤朋恵, 他
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジルセリンは自己免疫性肝炎を緩解する2012

    • Author(s)
      鈴木健介, 他
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] Ectodomain shedding of TGFα as a versatile readout for GPCR activation2012

    • Author(s)
      Asuka Inoue, 他
    • Organizer
      Keystone Symposia G Protein-Coupled Receptors : Molecular Mechanisms and Novel Functional Insights
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development and characterization of TGFalpha shedding assay : a novel and powerful method to detect G12/13 signaling2012

    • Author(s)
      Jun Ishiguro, 他
    • Organizer
      Keystone Symposia G Protein-Coupled Receptors : Molecular Mechanisms and Novel Functional Insights
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] An improved method for the detection of phospholipids2012

    • Author(s)
      Keita Nakanaga, 他
    • Organizer
      The 7th KOREA-JAPAN conference on cellular signaling for young scientists
    • Place of Presentation
      Ulsan, Korea
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Mechanism of LPA-mediated vasculogenesis2012

    • Author(s)
      Hiroshi Yukiura, 他
    • Organizer
      The 7th KOREA-JAPAN conference on cellular signaling for young scientists
    • Place of Presentation
      Ulsan, Korea
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジルセリンによる免疫抑制作用2012

    • Author(s)
      巻出久美子, 他
    • Organizer
      新学術領域若手ワークショップ
    • Place of Presentation
      東京
    • Year and Date
      2012-02-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規LysoPS受容体の同定2012

    • Author(s)
      奥谷倫世, 他
    • Organizer
      新学術領域若手ワークショップ
    • Place of Presentation
      東京
    • Year and Date
      2012-02-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] ゼブラフィッシュにおけるLPAの機能2012

    • Author(s)
      雪浦弘志, 他
    • Organizer
      新学術領域若手ワークショップ
    • Place of Presentation
      東京
    • Year and Date
      2012-02-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Immunosuppressive roles of lysophosphatidylserine in mice2011

    • Author(s)
      Kumito Makide, 他
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effects of lysophophatidylserine on lymphocytes2011

    • Author(s)
      Hajime Kitamura, 他
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸受容体LPA3を介した迷走神経活性化の解明2011

    • Author(s)
      可野邦行, 他
    • Organizer
      ファーマ・バイオフォーラム2011
    • Place of Presentation
      仙台
    • Year and Date
      2011-10-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 骨形成におけるLPAシグナリングの役割の解明2011

    • Author(s)
      板井恵理子, 他
    • Organizer
      ファーマ・バイオフォーラム2011
    • Place of Presentation
      仙台
    • Year and Date
      2011-10-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 2-アシル型リゾリン脂質の検出とその受容体活性化機構の解析2011

    • Author(s)
      首藤啓明, 他
    • Organizer
      ファーマ・バイオフォーラム2011
    • Place of Presentation
      仙台
    • Year and Date
      2011-10-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] ゼブラフィッシュ体節間血管形成におけるリゾホスファチジン酸シグナルの作用機序2011

    • Author(s)
      濱弘太郎, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 生理活性リゾリン脂質の定量系の開発と産生機構の解析2011

    • Author(s)
      井上飛鳥, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたLPAシグナリングの骨形成シグナリングにおける機能解析2011

    • Author(s)
      有馬直明, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸受容体LPA3を介した求心性迷走神経活性化作用の解析2011

    • Author(s)
      可野邦行, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジルセリンの細胞接着抑制作用2011

    • Author(s)
      北村一, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規GPCRシグナル検出法~TGFalpha切断アッセイ~の開発2011

    • Author(s)
      石黒純, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジルセリンの免疫抑制作用2011

    • Author(s)
      奥谷倫世, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 2-アシル型リゾリン脂質の検出とその受容体活性化機構の解析2011

    • Author(s)
      首藤啓明, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 骨形成におけるLPAシグナリングの役割の解明2011

    • Author(s)
      板井恵理子, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血管形成におけるLPAシグナル調節機構の解析2011

    • Author(s)
      雪浦弘志, 他
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] New aspects of autotaxin : structure and function2011

    • Author(s)
      Junken Aoki, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy(招待講演)
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] The characterization of ATX and LPA receptors in zebrafish2011

    • Author(s)
      Kotaro Hama, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] TGF-alpha ectodomain shedding underlies LPA-induced hair formation2011

    • Author(s)
      Asuka Inoue, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] LPA signaling in bone development2011

    • Author(s)
      Naoaki Arima, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Activation of vagal afferents via lysophosphatidic acid-3 receptor in mice2011

    • Author(s)
      Kuniyuki Kano, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Autotaxin-lysophosphatidic acid signaling functionally modulate sphingosine-1-phosphate signaling2011

    • Author(s)
      Keita Nakanaga, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Regulation of LPA signal in blood vessel formation2011

    • Author(s)
      Hiroshi Yukiura, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸は体毛形成に関与する2011

    • Author(s)
      井上飛鳥, 他
    • Organizer
      日本生化学会東北支部第77回例会・シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2011-07-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸産生酵素オートタキシンの結晶構造解析2011

    • Author(s)
      奥平真一, 他
    • Organizer
      日本生化学会東北支部第77回例会・シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2011-07-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] LPAによる血管透過性亢進作用メカニズムの解明2011

    • Author(s)
      近藤朋恵, 他
    • Organizer
      日本生化学会東北支部第77回例会・シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2011-07-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規AutotaxinスプライシングアイソフォームATXδの性状解析2011

    • Author(s)
      橋本崇史, 他
    • Organizer
      日本生化学会東北支部第77回例会・シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2011-07-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] Lysophosphatidic acid signaling in zebrafish vascular formation2011

    • Author(s)
      Kotaro Hama, 他
    • Organizer
      第30回内藤コンファレンス
    • Place of Presentation
      札幌
    • Year and Date
      2011-06-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Role of lysophosphatidylserine in inflammation-associated mast cell degranulation2011

    • Author(s)
      Kumiko Makide, 他
    • Organizer
      第30回内藤コンファレンス
    • Place of Presentation
      札幌
    • Year and Date
      2011-06-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸産生酵素オートタキシンの結晶構造解析2011

    • Author(s)
      奥平真一, 他
    • Organizer
      第53回日本脂質生化学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] リゾホスファチジン酸受容体LPA3を介した求心性迷走神経活性化作用の解析2011

    • Author(s)
      可野邦行, 他
    • Organizer
      第53回日本脂質生化学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] 骨形成におけるLPAシグナリングの役割の解明2011

    • Author(s)
      板井恵理子, 他
    • Organizer
      第53回日本脂質生化学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] ホスホリパーゼA1(PLA1)により産生される2-アシル型リゾリン脂質の分離とその性状解析2011

    • Author(s)
      首藤啓明, 他
    • Organizer
      第53回日本脂質生化学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Mechanism of extracellular production of bioactive lysophospholipids using a newly developed LC-MS/MS method2011

    • Author(s)
      Asuka Inoue, 他
    • Organizer
      LIPID MAPS Annual Meeting 2011
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-05-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血管形成におけるオートタキシン-LPAシグナルの解析2011

    • Author(s)
      雪浦弘志
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡、静岡県コンベンションアーツセンター
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] モデル生物を用いたLPAシグナルの作用機序の解析2011

    • Author(s)
      濱弘太郎
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡、静岡県コンベンションアーツセンター
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] リゾホスファチジン酸受容体LPA_3を介した求心性迷走神経活性化作用の解析2011

    • Author(s)
      可野邦行
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡、静岡県コンベンションアーツセンター
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 炎症時におけるリゾホスファチジルセリン産生の変動解析2011

    • Author(s)
      奥谷倫世
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡、静岡県コンベンションアーツセンター
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規GPCRシグナル検出法-TGFα切断アッセイ-の開発2011

    • Author(s)
      石黒純
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡、静岡県コンベンションアーツセンター
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] LC-ESI-MS/MSを用いた生理活性リゾリン脂質定量系の開発2011

    • Author(s)
      井上飛鳥
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡、静岡県コンベンションアーツセンター
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたLPAシグナリングの骨形成における機能解析2010

    • Author(s)
      有馬直明
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] LC-ESI-MS/MSを用いたリゾホスファチジルセリンおよびリゾホスファチジルスレオニンの検出2010

    • Author(s)
      奥谷倫世
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胎生期骨形成におけるLPAシグナリングの役割の解明2010

    • Author(s)
      板井恵理子
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 広範なGPCRシグナルを検出する新規測定法-TGFα切断アッセイ-の開発2010

    • Author(s)
      石黒純
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] リゾホスファチジルセリンの活性化リンパ球に対する効果2010

    • Author(s)
      北村一
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] PLA1型リゾリン脂質産生酵素の受容体活性化機構の解析2010

    • Author(s)
      首藤啓明
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] LPA_3を介した降圧・徐脈作用機構の解明2010

    • Author(s)
      可野邦行
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肺・腎線維化における生理活性脂質リゾホスファチジン酸の役割2010

    • Author(s)
      奥平真一
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] モデル生物を用いたLPAシグナルの作用機序の解析2010

    • Author(s)
      濱弘太郎
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 炎症反応のマスト細胞活性化におけるリゾホスファチジルセリンの役割2010

    • Author(s)
      巻出久美子
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血管形成におけるオートタキシン-LPAシグナルの解析2010

    • Author(s)
      雪浦弘志
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] ATX-LPAシグナルによるS1Pシグナルの抑制2010

    • Author(s)
      中永景太
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規AutotaxinスプライシングアイソフォームATXΦの性状解析2010

    • Author(s)
      橋本崇史
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] リゾホスファチジン酸受容体LPA_3特異的アゴニストによる気管収縮作用の解析2010

    • Author(s)
      近藤朋恵
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫、神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肺・腎線維化における生理活性脂質リゾホスファチジン酸の役割2010

    • Author(s)
      奥平真一
    • Organizer
      第32回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      富山、富山国際会議場
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] NPP6の肝臓における発現解析2010

    • Author(s)
      山本泰生
    • Organizer
      第49回日本薬学会東北支部大会
    • Place of Presentation
      福島、奥羽大学
    • Year and Date
      2010-10-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肺・腎線維化における生理活性脂質リゾホスファチジン酸の役割2010

    • Author(s)
      奥平真一
    • Organizer
      第49回日本薬学会東北支部大会
    • Place of Presentation
      福島、奥羽大学
    • Year and Date
      2010-10-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] LC-ESI-MS/MSを用いたリゾホスファチジルセリンの検出2010

    • Author(s)
      奥谷倫世
    • Organizer
      第49回日本薬学会東北支部大会
    • Place of Presentation
      福島、奥羽大学
    • Year and Date
      2010-10-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] ホスファチジルセリン特異的ホスホリパーゼA1の病理的機能の解明2010

    • Author(s)
      佐藤侑介
    • Organizer
      第49回日本薬学会東北支部大会
    • Place of Presentation
      福島、奥羽大学
    • Year and Date
      2010-10-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] TGFα切断アッセイを用いたオーファンGPCRのリガンドスクリーニング2010

    • Author(s)
      石黒純
    • Organizer
      第9回次世代を担う若手ファーマ・バイオフォーラム2010
    • Place of Presentation
      京都、京都大学大学院薬学研究科
    • Year and Date
      2010-10-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] LPS受容体P2Y10の同定と細胞接着における機能2010

    • Author(s)
      北村一
    • Organizer
      第9回次世代を担う若手ファーマ・バイオフォーラム2010
    • Place of Presentation
      京都、京都大学大学院薬学研究科
    • Year and Date
      2010-10-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血管形成におけるオートタキシン-LPAシグナルの解析2010

    • Author(s)
      雪浦弘志
    • Organizer
      第9回次世代を担う若手ファーマ・バイオフォーラム2010
    • Place of Presentation
      京都、京都大学大学院薬学研究科
    • Year and Date
      2010-10-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたLPAシグナリングの骨形成における機能解析2010

    • Author(s)
      有馬直明
    • Organizer
      第16回小型魚類研究会
    • Place of Presentation
      埼玉、プラザイースト
    • Year and Date
      2010-09-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いた生理活性脂質の機能解析2010

    • Author(s)
      中永景太
    • Organizer
      第16回小型魚類研究会
    • Place of Presentation
      埼玉、プラザイースト
    • Year and Date
      2010-09-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血管形成におけるオートタキシン-LPAシグナルの解析2010

    • Author(s)
      雪浦弘志
    • Organizer
      第16回小型魚類研究会
    • Place of Presentation
      埼玉、プラザイースト
    • Year and Date
      2010-09-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Roles of Autotaxin in Pulmonary Fibrosis2010

    • Author(s)
      奥平真一
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Kobe Port Island
    • Year and Date
      2010-08-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Roles of Autotaxin in Pulmonary Fibrosis2010

    • Author(s)
      奥平真一
    • Organizer
      The 27th Naito Conference on Menmbrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      Sapporo, CHATERAISE Gateaux Kingdom SAPPORO
    • Year and Date
      2010-06-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] Lysophosphatidic acid plays a critical role in hair follicle formation through TGF-alpha release and EGFR transactivation2010

    • Author(s)
      井上飛鳥
    • Organizer
      The 27th Naito Conference on Menmbrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      Sapporo, CHATERAISE Gateaux Kingdom SAPPORO
    • Year and Date
      2010-06-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      青木淳賢
    • Organizer
      International Vascular Biology Meeting 2010
    • Place of Presentation
      Los Angels, CA, USA
    • Year and Date
      2010-06-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] The functional interaction between lysophosphatidic acid and sphingosin e-1-phosphate signaling in heart morphogenesis in zebrafish2010

    • Author(s)
      濱弘太郎
    • Organizer
      9th international conference on zebrafish development and genetics
    • Place of Presentation
      Madison, WI, USA
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] LC-ESI-MS/MSを用いたリゾリン脂質定量系の開発2010

    • Author(s)
      井上飛鳥
    • Organizer
      第52回日本脂質生化学会
    • Place of Presentation
      群馬、秋森旅館
    • Year and Date
      2010-06-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 様々な線維症におけるオートタキシンの寄与の解析2010

    • Author(s)
      奥平真一
    • Organizer
      第52回日本脂質生化学会
    • Place of Presentation
      群馬、秋森旅館
    • Year and Date
      2010-06-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] ATX-LPAシグナルによるSIPシグナル抑制2010

    • Author(s)
      中永景太
    • Organizer
      第52回日本脂質生化学会
    • Place of Presentation
      群馬、秋森旅館
    • Year and Date
      2010-06-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] オートタキシントランスジェニックマウスの解析2010

    • Author(s)
      雪浦弘志
    • Organizer
      第52回日本脂質生化学会
    • Place of Presentation
      群馬、秋森旅館
    • Year and Date
      2010-06-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] TGFα切断アッセイによるGPCRシグナルの検出2010

    • Author(s)
      石黒純
    • Organizer
      第52回日本脂質生化学会
    • Place of Presentation
      群馬、秋森旅館
    • Year and Date
      2010-06-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Lysophosphatidic acid plays a critical role in hair follicle formation through TGFa release and EGFR transactivation2010

    • Author(s)
      井上飛鳥
    • Organizer
      Keystone Symposia Bioactive Lipids : Biochemistry and Diseases (D2)
    • Place of Presentation
      Kyoto, Westin Miyako Kyoto
    • Year and Date
      2010-06-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      青木淳賢
    • Organizer
      Keystone Symposia Bioactive Lipids : Biochemistry and Diseases (D2)
    • Place of Presentation
      Kyoto, Westin Miyako Kyoto
    • Year and Date
      2010-06-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肺線維症におけるリゾホスファチジン酸産生酵素オートタキシンの機能解析2010

    • Author(s)
      奥平真一
    • Organizer
      第76回日本生化学会東北支部例会
    • Place of Presentation
      福島、コラッセふくしま
    • Year and Date
      2010-05-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] TGFα切断アッセイによるG12/13シグナルの検出2010

    • Author(s)
      石黒純
    • Organizer
      第7回GPCR研究会
    • Place of Presentation
      東京、日本科学未来館みらいCANホール
    • Year and Date
      2010-05-07
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.pharm.tohoku.ac.jp/~seika/H21/index.html

    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi