Metabolomic analyses of omega-3 fatty acid metabolism and their physiological functions

• Project Area: Machineries of bioactive lipids in homeostasis and diseases
• Project/Area Number: 22116006
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: The Institute of Physical and Chemical Research (2014); The University of Tokyo (2010-2013)
• Principal Investigator: ARITA Makoto 独立行政法人理化学研究所, 統合生命医科学研究センター, チームリーダー (80292952)
• Project Period (FY): 2010-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥110,630,000 (Direct Cost: ¥85,100,000、Indirect Cost: ¥25,530,000); Fiscal Year 2014: ¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000); Fiscal Year 2013: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000); Fiscal Year 2012: ¥21,710,000 (Direct Cost: ¥16,700,000、Indirect Cost: ¥5,010,000); Fiscal Year 2011: ¥21,840,000 (Direct Cost: ¥16,800,000、Indirect Cost: ¥5,040,000); Fiscal Year 2010: ¥29,380,000 (Direct Cost: ¥22,600,000、Indirect Cost: ¥6,780,000)
• Keywords: 生理活性脂質 / 脂肪酸代謝 / 抗炎症作用 / メタボロミクス / 生理活性物質 / 脂質メディエーター / ω３脂肪酸 / インフルエンザウイルス感染 / 分析化学

Outline of Final Research Achievements

We established LC-MS/MS-based lipidomics system to monitor more than 500 of fatty acid metabolites simultaneously. From EPA-lipidomics, we identified potent anti-inflammatory metabolites, namely 17,18-diHEPE and 12-OH-17,18-EpETE, that belong to unique omega-3 PUFA metabolic pathway. By using omega-3 desaturase (fat-1) transgenic mouse, we identified cardioprotective function of macrophage-derived EPA metabolite 18-HEPE. Also we found dysregulated synthesis of omega-3 PUFA-derived anti-inflammatory mediator protectin D1 in eosinophils from patients with severe asthma.

Research Products

• [Journal Article] n-3 fatty acids effectively improve the reference memory-related learning ability associated with increased brain docosahexaenoic acid-derived docosanoids in aged rats. (2015)
  • Author(s): Hashimoto M, Katakura M, Tanabe Y, Al Mamun A, Inoue T, Hossain S, Arita M, Shido O.
  • Journal Title: Biochim. Biophys. Acta Volume: 1851 Issue: 2 Pages: 203-209
  • DOI: 10.1016/j.bbalip.2014.10.009
  • NAID: 120006938648
  • Peer Reviewed / Open Access
• [Journal Article] A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway. (2015)
  • Author(s): Junki Miyamoto, Taichi Mizukure, Si-Bum Park, Shigenobu Kishino, Ikuo Kimura, Kanako Hirano, Paolo Bergamo, Mauro Rossi, Takuya Suzuki, Makoto Arita, Jun Ogawa, and Soichi Tanabe
  • Journal Title: Journal of Biological Chemistry. Volume: 290 Issue: 5 Pages: 2902-2918
  • DOI: 10.1074/jbc.m114.610733
  • Peer Reviewed / Open Access
• [Journal Article] Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases (2015)
  • Author(s): Miyata J, Arita M.
  • Journal Title: Allergology International Volume: 64 Issue: 1 Pages: 27-34
  • DOI: 10.1016/j.alit.2014.08.003
  • NAID: 130004873127
  • ISSN: 1323-8930, 1440-1592
  • Peer Reviewed / Open Access
• [Journal Article] ω３脂肪酸の代謝と心臓保護作用 (2015)
  • Author(s): 有田誠
  • Journal Title: 別冊BIO Clinica Volume: 4 Pages: 99-110
• [Journal Article] 脂肪酸代謝と炎症のメタボロミクス (2015)
  • Author(s): 有田誠
  • Journal Title: 臨床免疫・アレルギー科 Volume: 63 Pages: 118-124
• [Journal Article] 18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling (2014)
  • Author(s): Endo J, Sano M, Isobe Y, Fukuda K, Kang JX, Arai H, Arita M.
  • Journal Title: J. Exp. Med. Volume: 211 Issue: 8 Pages: 1673
  • DOI: 10.1084/jem.20132011
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Identification of 14,2 (2014)
  • Author(s): Yoshiyuki Yokokura, Yosuke Isobe, Shinnosuke Matsueda, Ryo Iwamoto, Tomomi Goto, Takeshi Yoshioka, Daisuke Urabe, Masayuki Inoue, Hiroyuki Arai and Makoto Arita
  • Journal Title: the journal of biochemistry Volume: 156 Issue: 6 Pages: 315
  • DOI: 10.1093/jb/mvu044
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Eosinophils control the resolution of inflammation and draining lymph node hypertrophy through the proresolving mediators and CXCL13 pathway in mice (2014)
  • Author(s): Tani Y, Arita M, Isobe Y, Imoto Y, Segi-Nishida E, Sugimoto Y, Arai H
  • Journal Title: FASEB J Volume: 28 Issue: 9 Pages: 4036
  • DOI: 10.1096/fj.14-251132
  • Peer Reviewed / Open Access
• [Journal Article] Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis (2014)
  • Author(s): Hirahashi J, Kawahata K, Arita M, Iwamoto R, Hishikawa K, Honda M, Hamasaki Y, Tanaka M, Okubo K, Kurosawa M, Takase O, Nakakuki M, Saiga K, Suzuki K, Kawachi S, Tojo A, Seki G, Marumo T, Hayashi M, Fujita T.
  • Journal Title: Sci. Rep Volume: 4 Issue: 1 Pages: 6406-6406
  • DOI: 10.1038/srep06406
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Regulation of intestinal IgA responses by dietary palmitic acid and its metabolism. (2014)
  • Author(s): Kunisawa J, Hashimoto E, Inoue A, Nagasawa R, Suzuki Y, Ishikawa I, Shikata S, Arita M, Aoki J, Kiyono H.
  • Journal Title: J. Immunol. Volume: 193 Issue: 4 Pages: 1666-1671
  • DOI: 10.4049/jimmunol.1302944
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The arachidonic acid metabolome as conserved regulator of cholesterol metabolism. (2014)
  • Author(s): Demetz E, Schroll A, Auer K, Heim C, Patsch JR, Eller P, Theurl M, Lener D, Stanzl U, Seifert M, Haschka D, Asshoff M, Dichtl S, Nairz M, Huber E, Stadlinger M, Li X, Pallweber P, Scharnagl H, Stojakovic T, Marz W, Kleber ME, Garlaschelli K, Uboldi P, Catapano AL, Kuba K, Imai Y, Arita M, Tancevski I.
  • Journal Title: Cell Metab. Volume: 20 Issue: 5 Pages: 787-798
  • DOI: 10.1016/j.cmet.2014.09.004
  • Peer Reviewed / Open Access
• [Journal Article] Identification of novel omega-3 fatty acid-derived bioactive metabolites based on a targeted lipidomics approach (2014)
  • Author(s): Isobe Y, Arita M.
  • Journal Title: Journal of Clinical Biochemistry and Nutrition Volume: 55 Issue: 2 Pages: 79-84
  • DOI: 10.3164/jcbn.14-18
  • NAID: 130004678432
  • ISSN: 0912-0009, 1880-5086
  • Peer Reviewed / Open Access
• [Journal Article] 脂肪酸代謝と炎症のメタボロミクス (2014)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ Volume: 249 Pages: 318-322
• [Journal Article] 呼吸器の脂肪酸代謝系がインフルエンザウイルス感染症から体を守る (2014)
  • Author(s): 今井由美子、有田誠
  • Journal Title: 実験医学増刊号「驚愕の代謝システム」 Volume: 32 Pages: 2389-2396
• [Journal Article] 脂肪酸代謝バランスと炎症の制御 (2014)
  • Author(s): 有田誠
  • Journal Title: 実験医学増刊号「炎症」 Volume: 32 Pages: 2796-2802
• [Journal Article] ω３系多価不飽和脂肪酸による心臓リモデリング抑制 (2014)
  • Author(s): 有田誠、遠藤仁
  • Journal Title: 循環plus Volume: 15 Pages: 7-9
• [Journal Article] Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo (2014)
  • Author(s): Taguchi A, Kawana K, Tomio K, Yamashita A, Isobe Y, Nagasaka K, Koga K, Inoue T, Nishida H, kojima S, Adachi K, Matsumoto Y, Arimoto T, Wada-Hiraike O, Oda K, kang JX, Arai H, Arita M, Osuga Y, Fujii T.
  • Journal Title: PLoS One Volume: 9 Issue: 2 Pages: e89605-e89605
  • DOI: 10.1371/journal.pone.0089605
  • Peer Reviewed
• [Journal Article] Omega-3 fatty acids protect renal functions by increasing docosahexaenoic acid-derived metabolite levels in SHR.Cg-Leprcp/NDmcr rats, a metabolic syndrome model. (2014)
  • Author(s): Katakura M, Hashimoto M, Inoue T, Al Mamun A, Tanabe Y, Iwamoto R, Arita M, Tsuchikura S, Shido O.
  • Journal Title: Molecules Volume: 15 Issue: 3 Pages: 3247-3263
  • DOI: 10.3390/molecules19033247
  • NAID: 120006901571
  • Peer Reviewed / Open Access
• [Journal Article] Combination therapy of 15-epi-lipoxin A4 with antibiotics protects mice from Escherichia coli-induced sepsis. (2014)
  • Author(s): Ueda T, Fukunaga K, Seki H, Miyata J, Arita M, Miyasho T, Obata T, Asano K, Betsuyaku T, Takeda J.
  • Journal Title: Crit Care Med Volume: 42 Issue: 4 Pages: 288-295
  • DOI: 10.1097/ccm.0000000000000162
  • Peer Reviewed
• [Journal Article] 炎症を制御する脂肪酸代謝物の包括的メタボロミクス (2014)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 248 Pages: 1199-1204
• [Journal Article] ω３脂肪酸の抗炎症作用とメタボロミクス (2014)
  • Author(s): 磯部洋輔、有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 248 Pages: 984-987
• [Journal Article] 炎症の収束に関わる脂質メディエーター (2014)
  • Author(s): 有田誠
  • Journal Title: 炎症と免疫（先端医学社） Volume: 22 Pages: 79-84
• [Journal Article] Eicosapentaenoic acid is converted via ω-3 epoxygenation to the anti-inflammatory metabolite 12-hydroxy-17,18-epoxyeicosatetraenoic acid (2013)
  • Author(s): Kubota T, Arita M, Isobe Y, Iwamoto R, Goto T, Yoshioka T, Urabe D, Inoue M, Arai H
  • Journal Title: FASEB J. Volume: 28 Issue: 2 Pages: 586
  • DOI: 10.1096/fj.13-236224
  • Peer Reviewed / Open Access
• [Journal Article] Omega-3 Polyunsaturated Fatty Acids Suppress the Cystic Lesion Formation of Peritoneal Endometriosis in Transgenic Mouse Models (2013)
  • Author(s): Tomio K, Kawana K, Taguchi A, Isobe Y, Iwamoto R, Yamashita A, Kojima S, Mori M, Nagamatsu T, Arimoto T, Oda K, Osuga Y, Taketani Y, Kang JX, Arai H, Arita M, Kozuma S, Fujii T.
  • Journal Title: PLoS One Volume: 8 Issue: 9 Pages: 2013-2013
  • DOI: 10.1371/journal.pone.0073085
  • Peer Reviewed
• [Journal Article] Increased tissue levels of omega-3 polyunsaturated fatty acids prevents pathological preterm birth (2013)
  • Author(s): Yamashita A, Kawana K, Tomio K, Taguchi A, Isobe Y, Iwamoto R, Masuda K, Furuya H, Nagamatsu T, Nagasaka K, Oda K, Wada-Hiraike O, Yamashita T, Taketani Y, Kang JX, Arai H, Arita M, Kozuma S, Fujii T.
  • Journal Title: Sci Rep Volume: 3 Issue: 1 Pages: 3113-3113
  • DOI: 10.1038/srep03113
  • Peer Reviewed
• [Journal Article] Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition (2013)
  • Author(s): Kishino S, Takeuchi M, Park S, Hirata A, Kitamura N, Kunisawa J, Kiyono H, Iwamoto R, Isobe Y, Arita M, Arai H, Ueda K, Shima J, Takahashi S, Yokozeki K, Shimizu S, Ogawa J.
  • Journal Title: Proc Natl Acad Sci USA Volume: 110 Issue: 44 Pages: 17808
  • DOI: 10.1073/pnas.1312937110
  • NAID: 120005341879
  • Peer Reviewed
• [Journal Article] Mast cell maturation is driven via a novel group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis. (2013)
  • Author(s): Taketomi, Y., Morimoto, K., Murakami, M., et al., 他30名
  • Journal Title: Nature Immunol. Volume: (印刷中) Issue: 6 Pages: 554-63
  • DOI: 10.1038/ni.2586
  • Peer Reviewed
• [Journal Article] Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators (2013)
  • Author(s): Miki Y, Yamamoto K, Taketomi Y, Sato H, Shimo K, Kobayashi T, Ishikawa Y, Ishii T, Nakanishi H, Ikeda K, Taguchi R, Kabashima K, Arita M, Arai H, Lambeau G, Bollinger JM, Hara S, Gelb MH, Murakami M.
  • Journal Title: J Exp Med. Volume: 210 Issue: 6 Pages: 1217
  • DOI: 10.1084/jem.20121887
  • Peer Reviewed
• [Journal Article] Inflammation and resolution are associated with upregulation of fatty acid beta-oxidation in zymosan-induced peritonitis. (2013)
  • Author(s): Fujieda Y, Manno A, Hayashi Y, Rhodes N, Guo L, Arita M, Bamba T, Fukusaki E.
  • Journal Title: PLoS One Volume: 8 Issue: 6 Pages: e66270-e66270
  • DOI: 10.1371/journal.pone.0066270
  • Peer Reviewed
• [Journal Article] Global metabolomic analysis of heart tissue in a hamster model for dilated cardiomyopathy. (2013)
  • Author(s): Maekawa K, Hirayama A, Iwata Y, Tajima Y, Nishimaki-Mogami T, Sugawara S, Ueno N, Abe H, Ishikawa M, Murayama M, Matsuzawa Y, Nakanishi H, Ikeda K, Arita M, Taguchi R, Minamino N, Wakabayashi S, Soga T, Saito Y.
  • Journal Title: J Mol Cell Cardiol Volume: 59 Pages: 76-85
  • DOI: 10.1016/j.yjmcc.2013.02.008
  • Peer Reviewed
• [Journal Article] Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer's disease. (2013)
  • Author(s): Tajima Y, Ishikawa M, Maekawa K, Murayama M, Senoo Y, Nishimaki-Mogami T, Nakanishi H, Ikeda K, Arita M, Taguchi R, Okuno A, Mikawa R, Niida S, Takikawa O, Saito Y.
  • Journal Title: Lipids Health Dis Volume: 12 Issue: 1 Pages: 68-68
  • DOI: 10.1186/1476-511x-12-68
  • Peer Reviewed
• [Journal Article] Effects of long-term oral administration of arachidonic acid and docosahexaenoic acid on the immune functions of young rats. (2013)
  • Author(s): Juman S, Hashimoto M, Katakura M, Inoue T, Tanabe Y, Arita M, Miki T, Shido O.
  • Journal Title: Nutrients Volume: 5 Issue: 6 Pages: 1949-1961
  • DOI: 10.3390/nu5061949
  • NAID: 120007000504
  • Peer Reviewed
• [Journal Article] ω３脂肪酸代謝産物のメタボローム解析と抗炎症作用 (2013)
  • Author(s): 久保田唯史、磯部洋輔、有田誠
  • Journal Title: 血栓と循環（メディカルレビュー社） Volume: 21 Pages: 195-199
• [Journal Article] オメガ３系多価不飽和脂肪酸の代謝と抗炎症作用 (2013)
  • Author(s): 有田誠
  • Journal Title: Cardiovascular Contemporary (Medicine Rattle) Volume: 2 Pages: 32-37
• [Journal Article] リピドミクス解析のアレルギー研究への応用 (2013)
  • Author(s): 宮田純、有田誠
  • Journal Title: 実験医学増刊「病態の理解に向かうアレルギー疾患研究」（羊土社） Volume: 31 Pages: 2852-2858
• [Journal Article] 好酸球による炎症とホメオスタシスの制御 (2013)
  • Author(s): 松枝進之介、磯部洋輔、有田誠
  • Journal Title: 炎症と免疫（先端医学社） Volume: 21 Pages: 450-454
• [Journal Article] 組織炎症の制御におけるn-3/n-6系脂肪酸バランスの重要性 (2013)
  • Author(s): 松枝進之介、有田誠
  • Journal Title: 内分泌・糖尿病・代謝内科（科学評論社） Volume: 36 Pages: 485-489
• [Journal Article] 脂肪酸バランスと炎症の制御 (2013)
  • Author(s): 有田誠
  • Journal Title: 静脈経腸栄養（JSPEN） Volume: 28 Pages: 929-932
  • NAID: 130004487311
• [Journal Article] Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E3 (2013)
  • Author(s): Y Isobe, M. Arita, R. Iwamoto, D. Urabe, H. Todoroki, K. Masuda, M. Inoue and H. Arai
  • Journal Title: The Journal of Biochemistry Volume: 153 Issue: 4 Pages: 355
  • DOI: 10.1093/jb/mvs151
  • NAID: 40019622680
  • Peer Reviewed
• [Journal Article] The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza (2013)
  • Author(s): Morita M, Kuba K, Ichikawa A, Nakayama M, Katahira J, Iwamoto R, Watanebe T, Sakabe S, Daidoji T, Nakamura S, Kadowaki A, Ohto T, Nakanishi H, Taguchi R, Nakaya T, Murakami M, Yoneda Y, Arai H, Kawaoka Y, Penninger JM, Arita M, Imai Y.
  • Journal Title: Cell Volume: 153 Issue: 1 Pages: 112
  • DOI: 10.1016/j.cell.2013.02.027
  • Peer Reviewed
• [Journal Article] Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma (2013)
  • Author(s): Miyata J, Fukunaga K, Iwamoto R, Isobe Y, Niimi K, Takamiya R, Takihara T, Tomomatsu K, Suzuki Y, Oguma T, Sayama K, Arai H, Betsuyaku T, Arita M, Asano K.
  • Journal Title: J Allergy Clin Immunol Volume: 131 Issue: 2 Pages: 353
  • DOI: 10.1016/j.jaci.2012.07.048
  • Peer Reviewed
• [Journal Article] オメガ３脂肪酸の代謝と炎症の制御 (2013)
  • Author(s): 有田誠
  • Journal Title: BIOINDUSTRY（シーエムシー出版） Volume: 347 Pages: 11-17
• [Journal Article] 炎症のメタボローム解析から明らかになった好酸球の新規機能 (2013)
  • Author(s): 有田誠
  • Journal Title: 生化学（日本生化学会） Volume: 85 Pages: 97-102
  • NAID: 10031156449
• [Journal Article] 炎症の収束に関わる脂質メディエーターの新規機能 (2012)
  • Author(s): 有田誠
  • Journal Title: バイオサイエンスとインダストリー（バイオインダストリー協会） Volume: 71 Pages: 14-17
  • NAID: 10031140295
• [Journal Article] ω３/ω６脂肪酸バランスと炎症の制御 (2012)
  • Author(s): 有田誠
  • Journal Title: Surgery Frontier（メディカルレビュー社） Volume: 19 Pages: 428-430
• [Journal Article] Identification and structure determination of novel anti-inflammatory mediator resolvin E3, 17,18-dihydroxyeicosapentaenoic acid (2012)
  • Author(s): Isobe Y, * Arita M, Matsueda S, Iwamoto R, Fujihara T, Nakanishi H, Taguchi R, Masuda K, Sasaki K, Urabe D, Inoue M, Arai H
  • Journal Title: J. Biol. Chem Volume: 287 Issue: 13 Pages: 10525
  • DOI: 10.1074/jbc.m112.340612
  • Peer Reviewed
• [Journal Article] Mediator lipidomics in acute inflammation and resolution (2012)
  • Author(s): Arita M
  • Journal Title: The Journal of Biochemistry Volume: 152 Issue: 4 Pages: 313-319
  • DOI: 10.1093/jb/mvs092
  • NAID: 10031166144
  • Peer Reviewed
• [Journal Article] Emerging roles of eosinophils and eosinophil-derived lipid mediators in the resolution of inflammation (2012)
  • Author(s): Isobe Y, et al.
  • Journal Title: Frontiers in Immunology Volume: 3
  • DOI: 10.3389/fimmu.2012.00270
  • Peer Reviewed
• [Journal Article] Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice (2011)
  • Author(s): Yamada T, et al
  • Journal Title: The FASEB Journal Volume: 25 Pages: 561-568
  • Peer Reviewed
• [Journal Article] Total synthesis and bioactivities of two proposed structures of maresin (2011)
  • Author(s): Sasaki K, et al
  • Journal Title: Chem Asian Journal Volume: 6 Pages: 534-543
  • Peer Reviewed
• [Journal Article] ω3系脂肪酸の代謝と抗炎症作用 (2011)
  • Author(s): 有田誠
  • Journal Title: アンチエイジング医学 Volume: 7 Pages: 506-510
• [Journal Article] 炎症の収束における脂質メディエーター代謝系のダイナミックな変化とその機能的役割 (2011)
  • Author(s): 有田誠
  • Journal Title: 実験医学増刊号「慢性炎症」 Volume: 29 Pages: 1524-1528
• [Journal Article] 炎症と動脈硬化、脂質メディエーター (2011)
  • Author(s): 遠藤仁、有田誠
  • Journal Title: 日本臨床 Volume: 69 Pages: 34-38
• [Journal Article] Transgenic restoration of long chain omega-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high fat-fed mice (2010)
  • Author(s): White PJ, et al
  • Journal Title: Diabetes Volume: 59 Pages: 3066-3073
  • Peer Reviewed
• [Journal Article] Resolvins as regulators of the immune system (2010)
  • Author(s): Seki H, et al
  • Journal Title: The Scientific World Journal Volume: 10 Pages: 818-831
  • Peer Reviewed
• [Journal Article] 炎症反応を制御する抗炎症性脂質メディエーター (2010)
  • Author(s): 有田誠
  • Journal Title: 実験医学増刊号「分子から個体へと深化する脂質生物学」 Volume: 28 Pages: 3401-3408
• [Journal Article] 血小板内皮細胞相互作用と脂質メディエーター (2010)
  • Author(s): 遠藤仁、有田誠
  • Journal Title: 血栓と循環 Volume: 18 Pages: 135-139
• [Presentation] オメガ３脂肪酸の抗炎症作用についての包括的メタボローム解析 (2015)
  • Author(s): 磯部洋輔、有田誠
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学（兵庫県神戸市）
  • Year and Date: 2015-03-26
  • Invited
• [Presentation] 新規脂質メディエーターによる炎症制御 (2015)
  • Author(s): 有田誠
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学（兵庫県神戸市）
  • Year and Date: 2015-03-26
  • Invited
• [Presentation] 脂肪酸メタボロミクスと炎症の制御 (2015)
  • Author(s): 有田誠
  • Organizer: 第９回レドックス・ライフイノベーションシンポジウム
  • Place of Presentation: 理化学研究所横浜キャンパス（神奈川県横浜市）
  • Year and Date: 2015-03-12
  • Invited
• [Presentation] Genetic and lipidomic approach for anti-inflammatory functions of omega-3 polyunsaturated fatty acids (2015)
  • Author(s): Makoto Arita
  • Organizer: PLM2015
  • Place of Presentation: 京王プラザホテル（東京都新宿区）
  • Year and Date: 2015-02-10
  • Invited
• [Presentation] Lipidomic approach to uncover anti-inflammatory mechanisms by omega-3 polyunsaturated fatty acids (2015)
  • Author(s): Makoto Arita
  • Organizer: BK Symposium
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2015-02-05
  • Invited
• [Presentation] オメガ３脂肪酸の代謝と抗炎症作用のメタボロミクス (2015)
  • Author(s): 有田誠
  • Organizer: 第５回日本生物工学会学際的脂質創生研究部会
  • Place of Presentation: 京都大学理学部セミナーハウス（京都府京都市）
  • Year and Date: 2015-01-23
  • Invited
• [Presentation] 腸内細菌と脂肪酸代謝のメタボロミクス (2015)
  • Author(s): 有田誠
  • Organizer: 第５回腸内細菌脂質代謝研究会
  • Place of Presentation: 京都大学農学部（京都府京都市）
  • Year and Date: 2015-01-22
  • Invited
• [Presentation] 脂肪酸代謝と病態・バイオロジー（量から質へ） (2014)
  • Author(s): 有田誠
  • Organizer: 第７回MetS Associated Cancer研究会
  • Place of Presentation: 国際ホテル宇部（山口県宇部市）
  • Year and Date: 2014-12-16
  • Invited
• [Presentation] オメガ３脂肪酸の分子栄養学 (2014)
  • Author(s): 有田誠
  • Organizer: 第４回脂質栄養セミナー
  • Place of Presentation: 麻布大学（神奈川県相模原市）
  • Year and Date: 2014-11-29
  • Invited
• [Presentation] 脂肪酸代謝バランスと炎症性疾患の制御 (2014)
  • Author(s): 有田誠
  • Organizer: 第１３回ホスファチジルセリン研究会
  • Place of Presentation: 東京海洋大学（東京都港区）
  • Year and Date: 2014-11-07
  • Invited
• [Presentation] Genetic and lipidomic approach to uncover cardioprotective mechanisms by omega-3 polyunsaturated fatty acids (2014)
  • Author(s): Makoto Arita
  • Organizer: 5th European Workshop on Lipid Mediators
  • Place of Presentation: Istanbul, Turkey
  • Year and Date: 2014-10-23
• [Presentation] n-3系脂肪酸の代謝と炎症性疾患の制御についてのメタボローム解析 (2014)
  • Author(s): 有田誠
  • Organizer: 第８７回日本生化学会
  • Place of Presentation: 京都国際会館（京都府京都市）
  • Year and Date: 2014-10-15
  • Invited
• [Presentation] n-3系多価不飽和脂肪酸による心臓リモデリング抑制機構の解析 (2014)
  • Author(s): 有田誠
  • Organizer: 心血管膜輸送研究会2014
  • Place of Presentation: 岡崎統合バイオサイエンスセンター（愛知県岡崎市）
  • Year and Date: 2014-09-04
  • Invited
• [Presentation] 脂肪酸の質の違いと病態・バイオロジー (2014)
  • Author(s): 有田誠
  • Organizer: 日本脂質栄養学会第２３回大会
  • Place of Presentation: 東京国際交流館（東京都江東区）
  • Year and Date: 2014-08-29
  • Invited
• [Presentation] 脂肪酸代謝バランスによる心疾患制御の分子メカニズムの解析 (2014)
  • Author(s): 有田誠
  • Organizer: 第１５回AB Conference
  • Place of Presentation: 横浜ベイシェラトンホテル（神奈川県横浜市）
  • Year and Date: 2014-08-02
  • Invited
• [Presentation] n-3系脂肪酸の代謝と心血管保護作用についてのメタボローム研究 (2014)
  • Author(s): 有田誠
  • Organizer: 第４６回日本動脈硬化学会総会
  • Place of Presentation: 京王プラザホテル（東京都新宿区）
  • Year and Date: 2014-07-10
  • Invited
• [Presentation] Genetic and lipidomic approach for the anti-inflammatory properties of omega-3 fatty acid (2014)
  • Author(s): Makoto Arita
  • Organizer: 55th International Conference on the Bioscience of Lipids
  • Place of Presentation: Aberdeen, Scotland
  • Year and Date: 2014-06-24
  • Invited
• [Presentation] Mediator lipidomics approach to understand the roles of fatty acid metabolism in controlling inflammation and tissue homeostasis (2014)
  • Author(s): Makoto Arita
  • Organizer: 18th Annual Meeting of Intestinal Microbiology
  • Place of Presentation: 伊藤国際学術研究センター（東京都文京区）
  • Year and Date: 2014-06-12
  • Invited
• [Presentation] n-3系脂肪酸はなぜ体に良いか (2014)
  • Author(s): 有田誠
  • Organizer: 第１４回抗加齢医学会総会
  • Place of Presentation: 大阪国際会議場（大阪府大阪市）
  • Year and Date: 2014-06-08
  • Invited
• [Presentation] オメガ３系脂肪酸と炎症性疾患の制御 (2014)
  • Author(s): 有田誠
  • Organizer: 第５６回日本脂質生化学会
  • Place of Presentation: 近畿大学東大阪キャンパス（大阪府東大阪市）
  • Year and Date: 2014-06-07
  • Invited
• [Presentation] 脂肪酸代謝と炎症のメタボロミクス (2014)
  • Author(s): 有田誠
  • Organizer: 第６回分子骨格筋代謝研究会
  • Place of Presentation: 京都大学人間・環境学研究科（京都府京都市）
  • Year and Date: 2014-05-18
  • Invited
• [Presentation] Identification of 17,18-diHEPE as a novel EPA-derived anti-inflammatory lipid mediator (2013)
  • Author(s): Yosuke Isobe, Makoto Arita, Shinnosuke Matsueda, Hiroki Nakanishi, Ryo Taguchi, Daisuke Urabe, Masayuki Inoue, Hiroyuki Arai
  • Organizer: Faseb SRC: Lysophospholipid and Other Related Medaitors-From Bench to Clinic
  • Place of Presentation: 北海道、ニセコ
• [Presentation] ω3系脂肪酸の代謝と抗炎症作用についてのメタボローム解析 (2012)
  • Author(s): 有田誠
  • Organizer: 第10回日本機能性食品医用学会
  • Place of Presentation: 東京(招待講演)
  • Year and Date: 2012-12-16
• [Presentation] Emerging role of eosinophils and eos inophil-derived lipid mediators in controlling inflammation and resolution. (2012)
  • Author(s): Makoto Arita
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡(招待講演)
  • Year and Date: 2012-12-14
• [Presentation] Emerging roles of lipid mediators in the resolution of inflammation (2012)
  • Author(s): Makoto Arita
  • Organizer: 日本免疫学会2012
  • Place of Presentation: 神戸(招待講演)
  • Year and Date: 2012-12-06
• [Presentation] 炎症の収束機構と脂肪酸代謝 (2012)
  • Author(s): 有田誠
  • Organizer: 第20回旭川心不全研究会
  • Place of Presentation: 北海道(招待講演)
  • Year and Date: 2012-10-12
• [Presentation] Lipid mediator metabolism in the resolution of inf lammation and potential drug development. (2012)
  • Author(s): Makoto Arita
  • Organizer: KSAP2012
  • Place of Presentation: Korea(招待講演)
  • Year and Date: 2012-10-05
• [Presentation] Emerging role of eosinophils and eos inophil-derived lipid mediators in acute inflammation and resolution. (2012)
  • Author(s): Makoto Arita
  • Organizer: 4th European Workshop on Lipid Mediators
  • Place of Presentation: Paris, France
  • Year and Date: 2012-09-27
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解析 (2012)
  • Author(s): 有田誠
  • Organizer: 第3回Molecular Cardiovascular Conference II
  • Place of Presentation: 北海道(招待講演)
  • Year and Date: 2012-09-07
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解析 (2012)
  • Author(s): 有田誠
  • Organizer: レドックスライフイノベーション
  • Place of Presentation: 栃木(招待講演)
  • Year and Date: 2012-08-24
• [Presentation] 炎症の収束における好酸球の新規機能 (2012)
  • Author(s): 有田誠
  • Organizer: 千里ライフサイエンスセミナー
  • Place of Presentation: 大阪(招待講演)
  • Year and Date: 2012-07-27
• [Presentation] Mediator Lipidomics in Inflammation Research (2012)
  • Author(s): Makoto Arita
  • Organizer: The 1st international symposium on Lipid Mediators
  • Place of Presentation: 福岡(招待講演)
  • Year and Date: 2012-06-06
• [Presentation] Identification of 17, 18-diHEPE as a novel EPA-derived anti-inflammatory lipid mediator (2012)
  • Author(s): Isobe Y., et al.
  • Organizer: Lipid MAPS annual meeting 2012
  • Place of Presentation: San Diego, USA
  • Year and Date: 2012-05-07
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解析 (2012)
  • Author(s): 有田誠
  • Organizer: 日本分子生物学会春季シンポジウム
  • Place of Presentation: 山梨(招待講演)
  • Year and Date: 2012-04-25
• [Presentation] Mediator lipidomics in inflammation and related diseases (2012)
  • Author(s): Makoto Arita
  • Organizer: 韓国薬学会
  • Place of Presentation: Jeju, Korea(招待講演)
  • Year and Date: 2012-04-20
• [Presentation] Mediator L ipidomics in Inflammat ion Research (2011)
  • Author(s): 有田誠
  • Organizer: 第19回日本血管生物医学会学術集会
  • Place of Presentation: 東京(招待講演)
  • Year and Date: 2011-12-10
• [Presentation] Mediator Lipidomics in Inflammation Research (2011)
  • Author(s): 有田誠
  • Organizer: 第19回日本血管生物医学会学術集会
  • Place of Presentation: 東京ステーションコンファレンス
  • Year and Date: 2011-12-10
• [Presentation] 炎症の収束に関わる脂質メディエーターの代謝と網羅的解析 (2011)
  • Author(s): 有田誠
  • Organizer: 第50回日本鼻科学会総会
  • Place of Presentation: 岡山(招待講演)
  • Year and Date: 2011-12-02
• [Presentation] 炎症の制御に関わる脂肪酸代謝物の包括的メタボローム解析 (2011)
  • Author(s): 有田誠
  • Organizer: 第50回日本鼻科学会
  • Place of Presentation: 岡山コンベンションセンター
  • Year and Date: 2011-12-02
• [Presentation] Arachidonic acid metabolites are regulatory signals for neural stem cell proliferation and differentiation (2011)
  • Author(s): Makoto Arita
  • Organizer: 5th Congress of the Internat ional Society of Nutrigenetics/Nutrigenomics
  • Place of Presentation: Beijing, China(招待講演)
  • Year and Date: 2011-11-17
• [Presentation] Mediator Lipidomics in Inflammation Research (2011)
  • Author(s): Makoto Arita
  • Organizer: 理研RCAI Seminar Series 2011
  • Place of Presentation: 横浜市、神奈川県
  • Year and Date: 2011-11-16
• [Presentation] Arachidonic acid metabolites are regulatory signals for neural stem cell proliferation and differentiation (2011)
  • Author(s): Makoto Arita
  • Organizer: 5th Congress of the International Society of Nutrigenetics/Nutrigenomics
  • Place of Presentation: Beijing, China
  • Year and Date: 2011-10-17
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解析 (2011)
  • Author(s): 有田誠
  • Organizer: 第6回メタボロームシンポジウム
  • Place of Presentation: 大阪(招待講演)
  • Year and Date: 2011-10-13
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解析 (2011)
  • Author(s): 有田誠
  • Organizer: 第6回メタボロームシンポジウム
  • Place of Presentation: 大阪大学
  • Year and Date: 2011-10-13
• [Presentation] Mediator Lipidomics:炎症を制御する細胞と脂質メディエーターのメタボロミクス (2011)
  • Author(s): 有田誠
  • Organizer: 国立医薬品食品衛生研究所セミナー
  • Place of Presentation: 国立医薬品食品衛生研究所(東京都)
  • Year and Date: 2011-10-06
• [Presentation] 脂肪酸由来の生理活性物質と炎症の制御 (2011)
  • Author(s): 有田誠
  • Organizer: 第2回機能油脂懇話会
  • Place of Presentation: 霧島国際音楽ホールみやまコンセール(鹿児島県)
  • Year and Date: 2011-10-01
• [Presentation] Novel role of eosinophils in controlling the resolution of acute inflammation by producing pro-resolving lipid mediators (2011)
  • Author(s): Makoto Arita
  • Organizer: 12th International Conference of bioactive Lipids in Cancer, Inflammlation and Related Diseases
  • Place of Presentation: Seattle, USA
  • Year and Date: 2011-09-21
• [Presentation] Novel role of eosinophils in controlling the resolution of acute inflammation by producing pro-resolving lipid mediators (2011)
  • Author(s): Makoto Arita
  • Organizer: 12th International Conference of Bioactive Lipids
  • Place of Presentation: Seattle, USA
  • Year and Date: 2011-09-21
• [Presentation] Eosinophils contribute to the resolution of acute peritonitis through the 12/15-lipoxygenase pathway (2011)
  • Author(s): Makoto Arita
  • Organizer: 10th World Congress on Inflamation
  • Place of Presentation: Paris, France
  • Year and Date: 2011-06-28
• [Presentation] Eosinophils contribute to the resolution of acute peritonitis through 12/15-lipoxygenase pathway (2011)
  • Author(s): Makoto Arita
  • Organizer: 10th World Congress of Inflammation
  • Place of Presentation: Paris, France
  • Year and Date: 2011-06-28
• [Presentation] Eosinophils promote resolution of acute peritonitis by producing 12/15-lipoxygenase-derived lipid mediators in mice (2011)
  • Author(s): Makoto Arita
  • Organizer: 7th Symposium for the International Eosinophil Society
  • Place of Presentation: Quebec, Canada
  • Year and Date: 2011-06-24
• [Presentation] Eosinophils promote resolution of acute peritonitis by producing 12/15-lipoxygenase-derived mediators in mice (2011)
  • Author(s): Makoto Arita
  • Organizer: Eosinophils 2011
  • Place of Presentation: Quebec, Canada
  • Year and Date: 2011-06-24
• [Presentation] 炎症を制御する脂肪酸代謝物の包括的メタボローム解析 (2011)
  • Author(s): 有田誠
  • Organizer: 第53回日本脂質生化学会
  • Place of Presentation: 東京(招待講演)
  • Year and Date: 2011-05-13
• [Presentation] 炎症を制御する脂肪酸代謝物の包括的メタボローム解析 (2011)
  • Author(s): 有田誠
  • Organizer: 第53回日本脂質生化学会
  • Place of Presentation: ホテルガーデンパレス(東京都)
  • Year and Date: 2011-05-13
• [Presentation] Eosinophils contribute to the resolution of acute peritonitis by producing pro-resolving lipid mediators (2011)
  • Author(s): Makoto Arita
  • Organizer: LIPID MAPS Annual Meeting 2011
  • Place of Presentation: La Jolla, USA
  • Year and Date: 2011-05-02
• [Presentation] 脂肪酸代謝と炎症のメタボロミクス (2011)
  • Author(s): 有田誠
  • Organizer: 第4回FANTASY
  • Place of Presentation: 東京都
  • Year and Date: 2011-02-06
• [Presentation] Eosinophils contribute to the resolution of acute peritonitis by producing pro-resolving mediators (2011)
  • Author(s): Makoto Arita
  • Organizer: TNF 2011
  • Place of Presentation: 淡路夢舞台国際会議場(兵庫県)
• [Presentation] Eosinophils contribute to the resolution of acute peritonitis by producing pro-resolving lipid mediators (2011)
  • Author(s): Makoto Arita
  • Organizer: LIPID MAPS 2011
  • Place of Presentation: La Jolla, USA
• [Presentation] Metabolomics of polyunsaturated fatty acid-derived mediators in controling inflammatory responses (2010)
  • Author(s): Makoto Arita
  • Organizer: 東京大学GCOE retreat
  • Place of Presentation: 幕張
  • Year and Date: 2010-12-11
• [Presentation] Metabolomics of polyunsaturated fatty acid-derived mediators in inflammation and resolution (2010)
  • Author(s): Makoto Arita
  • Organizer: BMB2010
  • Place of Presentation: 神戸ポートアイランド(兵庫県)
  • Year and Date: 2010-12-10
• [Presentation] Metabolomics of polyunsaturated fatty acid-derived lipid mediators in controling inflammation and resolution (2010)
  • Author(s): Makoto Arita
  • Organizer: RIKEN Symposium
  • Place of Presentation: 理化学研究所(埼玉県)
  • Year and Date: 2010-11-24
• [Presentation] Functional lipidomics of polyunsaturated fatty acid-derived mediators in inflammation and resolution (2010)
  • Author(s): Makoto Arita
  • Organizer: PSWC2010
  • Place of Presentation: New Orleans、USA
  • Year and Date: 2010-11-17
• [Presentation] 脂質メディエーターと炎症反応の収束 (2010)
  • Author(s): 有田誠
  • Organizer: Forum on Allergy in Nagoya
  • Place of Presentation: 名古屋
  • Year and Date: 2010-10-09
• [Presentation] 炎症を抑制する脂肪酸代謝物の包括的メタボローム解析 (2010)
  • Author(s): 有田誠
  • Organizer: 第13回炎症と循環器疾患研究会
  • Place of Presentation: 東京
  • Year and Date: 2010-07-23
• [Presentation] Metabolomic analysis of polyunsaturated fatty acid-derived mediators in inflammation (2010)
  • Author(s): Makoto Arita
  • Organizer: The 27th Naito Conference
  • Place of Presentation: シャトレーゼ ガトーキングダム サッポロ(北海道)
  • Year and Date: 2010-06-30
• [Presentation] 炎症を制御する脂肪酸代謝物のメタボローム研究 (2010)
  • Author(s): 有田誠
  • Organizer: 臨床アレルギー研究会
  • Place of Presentation: 富国生命ビル(東京都)
  • Year and Date: 2010-06-12
• [Presentation] 炎症を制御する脂質メディエーターの代謝と網羅的解析 (2010)
  • Author(s): 有田誠
  • Organizer: 第17回TVMフォーラム
  • Place of Presentation: 城山観光ホテル(鹿児島県)
  • Year and Date: 2010-04-22
• [Presentation] 炎症を制御する脂肪酸代謝物のメタボロミクス (2010)
  • Author(s): 有田誠
  • Organizer: The 2nd Brainstorm Medical Conference
  • Place of Presentation: 東京
  • Year and Date: 2010-04-17
• [Presentation] エイコサペンタエン酸由来の抗炎症性代謝物Resolvin E3の新規同定
  • Author(s): 磯部 洋輔, 有田 誠, 中西 広樹, 田口 良, 占部 大介, 井上 将行, 新井 洋由
  • Organizer: 日本ビタミン学会第65回大会
  • Place of Presentation: 東京都、一橋講堂
• [Presentation] 炎症を制御する細胞と脂質メディエーターのメタボローム解析
  • Author(s): 有田誠
  • Organizer: 第55回日本脂質生化学会
  • Place of Presentation: 宮城県、松島大観荘
  • Invited
• [Presentation] エイコサペンタエン酸の抗炎症作用についての包括的メタボローム解析
  • Author(s): 磯部 洋輔, 久保田 唯史, 岩本 涼, 有田 誠, 新井 洋由
  • Organizer: 第55回日本脂質生化学会
  • Place of Presentation: 宮城県、松島大観荘
• [Presentation] Eosinophils control the resolution of inflammation through the 12/15-lipoxygenase pathway
  • Author(s): Makoto Arita
  • Organizer: 9th Biennial Symposium of International Eosinophil Society
  • Place of Presentation: Oxford, UK
• [Presentation] Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma
  • Author(s): Jun Miyata, Koichi Fukunaga, Koichiro Asano, Makoto Arita
  • Organizer: 9th Biennial Symposium of International Eosinophil Society
  • Place of Presentation: Oxford, UK
• [Presentation] Mediator Lipidomics: 炎症を制御する細胞と脂質メディエーターのメタボロミクス
  • Author(s): 有田誠
  • Organizer: 第26回バイオメディカル分析科学シンポジウム
  • Place of Presentation: 東京都、昭和大学
  • Invited
• [Presentation] Emerging roles of eosinophils and eosinophil-derived lipid mediators in the resolution of acute inflammation
  • Author(s): Makoto Arita
  • Organizer: 15th International Congress of Immunology
  • Place of Presentation: Milan, Italy
• [Presentation] Emerging roles of eosinophils in the resolution of inflammation
  • Author(s): Makoto Arita
  • Organizer: 第86回日本生化学会大会
  • Place of Presentation: 神奈川県、パシフィコ横浜
  • Invited
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解明
  • Author(s): 有田誠
  • Organizer: ERATO/さきがけ共催シンポジウム 『先端メタボロミクスを駆使して展開する新しい代謝生物学』
  • Place of Presentation: 東京都、慶應大学医学部
  • Invited
• [Presentation] Mediator Lipidomics: 炎症を制御する細胞と脂質メディエーターのメタボロミクス
  • Author(s): 有田誠
  • Organizer: 第８回メタボロームシンポジウム
  • Place of Presentation: 福岡県、九州大学医学部百年講堂
  • Invited
• [Presentation] Emerging roles of eosinophils and eosinophil-derived lipid mediators in controlling inflammation and resolution
  • Author(s): Makoto Arita
  • Organizer: 13th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
  • Place of Presentation: San Juan, Puerto Rico
  • Invited
• [Presentation] 第三世代の脂質メディエーター：ω３脂肪酸と炎症抑制
  • Author(s): 有田誠
  • Organizer: 第３回都医学研シンポジウム
  • Place of Presentation: 東京都、津田ホール
  • Invited
• [Presentation] 炎症収束の制御における脂肪酸代謝系の役割
  • Author(s): 有田誠
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 兵庫県、神戸コンベンションセンター
  • Invited
• [Presentation] 脂肪酸メタボロミクスと病態・バイオロジー（量から質へ）
  • Author(s): 有田誠
  • Organizer: 第１回JFAS
  • Place of Presentation: 東京都、AKIBA HALL
  • Invited
• [Presentation] Emerging roles of lipid mediators in controlling inflammation and resolution
  • Author(s): Makoto Arita
  • Organizer: Symposium of Lipid Biology Division, Korea Society of Molecular and Cellular Biology
  • Place of Presentation: Busan, Korea
  • Invited
• [Presentation] n-3系脂肪酸の代謝と抗炎症作用についてのメタボローム解析
  • Author(s): 有田誠
  • Organizer: JSPEN2014
  • Place of Presentation: 神奈川県、パシフィコ横浜
  • Invited
• [Presentation] 炎症を制御する脂肪酸代謝のメタボロミクス
  • Author(s): 有田誠
  • Organizer: 腸内細菌脂質代謝研究会
  • Place of Presentation: 京都府、京都大学益川ホール
  • Invited
• [Presentation] ω3系脂肪酸の代謝と抗炎症作用
  • Author(s): 有田誠
  • Organizer: 第35回Osaka Diabetes Forum
  • Place of Presentation: 大阪府、ホテルグランヴィア大阪
  • Invited
• [Presentation] 炎症の収束に関わる細胞と脂質マシナリー
  • Author(s): 有田誠、谷友香子、磯部洋輔、新井洋由
  • Organizer: 第134回日本薬学会
  • Place of Presentation: 熊本県、熊本大学
  • Invited
• [Presentation] ω３系脂肪酸の代謝と抗炎症作用のメタボローム解析
  • Author(s): 有田誠、磯部洋輔、遠藤仁、新井洋由
  • Organizer: 第134回日本薬学会
  • Place of Presentation: 熊本県、熊本大学
  • Invited
• [Presentation] オメガ3脂肪酸由来の活性代謝物の構造と機能
  • Author(s): 磯部洋輔、有田誠
  • Organizer: 日本農芸化学会2014年度大会
  • Place of Presentation: 東京都、明治大学生田キャンパス
  • Invited
• [Presentation] Mediator lipidomics in inflammation and related diseases
  • Author(s): Makoto Arita
  • Organizer: Annual meeting of the Pharmaceutical Society of Korea
  • Place of Presentation: Jeju, Korea
  • Invited
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解析
  • Author(s): 有田誠
  • Organizer: 日本分子生物学会第12回春季シンポジウム
  • Place of Presentation: 山梨県、石和温泉
  • Invited
• [Presentation] Mediator lipidomics in inflammation research
  • Author(s): Makoto Arita
  • Organizer: The 1st International Symposium in Lipid Mediators
  • Place of Presentation: 福岡県、九州大学
• [Presentation] 炎症の収束における好酸球の新規機能
  • Author(s): 有田誠
  • Organizer: 千里ライフサイエンスセミナー
  • Place of Presentation: 大阪府、千里ライフサイエンスセンター
  • Invited
• [Presentation] 脂質メタボロミクスによる炎症の制御機構の解析
  • Author(s): 有田誠
  • Organizer: レドックスライフイノベーション
  • Place of Presentation: 栃木県、那須オオシマフォーラム
  • Invited
• [Presentation] 脂肪酸代謝と炎症のメタボロミクス
  • Author(s): 有田誠
  • Organizer: 第３回Molecular Cardiovascular Conference
  • Place of Presentation: 北海道、キロロ
  • Invited
• [Presentation] Emerging role of eosinophils and eosinophil-derived lipid mediators in acute inflammation and resolution
  • Author(s): Makoto Arita
  • Organizer: 4th European Workshop on Lipid Mediators
  • Place of Presentation: Paris, France
• [Presentation] Lipid mediator metabolism in the resolution of inflammation and potential drug development
  • Author(s): Makoto Arita
  • Organizer: KSAP2012
  • Place of Presentation: Kangwon, Korea
  • Invited
• [Presentation] Mediator lipidomics in inflammation research
  • Author(s): Makoto Arita
  • Organizer: JAFoS
  • Place of Presentation: Irvine, USA
  • Invited
• [Presentation] Emerging roles of lipid mediators in the resolution of inflmmation
  • Author(s): Makoto Arita
  • Organizer: 日本免疫学会2012
  • Place of Presentation: 兵庫県、神戸コンベンションセンター
  • Invited
• [Presentation] Emerging role of eosinophils and eosinophil-derived lipid mediators in controlling inflammation and resolution
  • Author(s): Makoto Arita
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡県、福岡国際会議場
  • Invited
• [Presentation] ω３系脂肪酸の代謝と抗炎症作用についてのメタボローム解析
  • Author(s): 有田誠
  • Organizer: 第10回日本機能性食品医用学会
  • Place of Presentation: 東京都、東京慈恵医科大学
  • Invited
• [Presentation] Emerging role of eosinophils and eosinophil-derived lipid mediators in controlling inflammation and resolution
  • Author(s): Makoto Arita
  • Organizer: The 2nd Ochanomizu Atherosclerosis Forum
  • Place of Presentation: 東京都、御茶ノ水
  • Invited
• [Presentation] Emerging roles of eosinophil-derived lipid mediators in controlling inflammation and resolution
  • Author(s): Makoto Arita
  • Organizer: JST-CREST International Symposium, Frontiers in Immunology and Inflammation
  • Place of Presentation: 東京都、一橋記念講堂
• [Book] 医用質量分析ガイドブック (2014)
  • Author(s): 有田誠、池田和貴
  • Total Pages: 6
  • Publisher: 診断と治療社
• [Book] 「最新生理活性脂質研究-実験手法、基礎的知識とその応用-」遺伝子医学MOOK 24号 (2013)
  • Author(s): 磯部洋輔、岩本涼、有田誠
  • Total Pages: 5
  • Publisher: メディカル ドゥ社
• [Book] そうだったんだ脂肪酸（循環器疾患との深い関係） (2013)
  • Author(s): 遠藤仁、有田誠
  • Total Pages: 7
  • Publisher: 文光堂
• [Book] Lipidomics (2012)
  • Author(s): Arita M, Iwamoto R, Isobe Y
  • Total Pages: 8
  • Publisher: WILEY-VCH
• [Book] 実験医学2月号 (2012)
  • Author(s): 有田誠編
  • Total Pages: 48
  • Publisher: 羊土社
• [Book] Lipidomics (2012)
  • Author(s): Arita M., et al. (Ekroos Ed.)
  • Total Pages: 336
  • Publisher: WILEY-VCH
• [Book] 試料分析講座:脂質分析 (2011)
  • Author(s): 有田誠, ら, 日本分析化学会編
  • Total Pages: 223
  • Publisher: 丸善出版株式会社
• [Remarks] 理化学研究所統合生命医科学研究センターメタボローム研究チーム
  • URL: http://www.ims.riken.jp/labo/53/index_j.html
• [Remarks]
  • URL: http://www.f.u-tokyo.ac.jp/~eisei/jp/Home.html
• [Patent(Industrial Property Rights)] アレルギー性疾患の予防または治療のための医薬組成物 (2013)
  • Inventor(s): 國澤純、清野宏、有田誠
  • Industrial Property Rights Holder: 東京大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2013-081548
  • Filing Date: 2013-04-19
• [Patent(Industrial Property Rights)] インフルエンザウイルス感染症の治療におけるプロテクチンD1の有効性 (2013)
  • Inventor(s): 今井由美子、久場敬司、有田誠、Josef Penninger
  • Industrial Property Rights Holder: 秋田大学、東京大学、IMBA
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2013-044813
  • Filing Date: 2013-03-06
• [Patent(Industrial Property Rights)] オメガ3脂肪酸由来の新規抗炎症性代謝物 (2010)
  • Inventor(s): 有田誠、新井洋由、磯部洋輔、久保田唯史
  • Industrial Property Rights Holder: 東京大学
  • Industrial Property Number: 2010-184473
  • Filing Date: 2010-08-19
• [Patent(Industrial Property Rights)] 光学活性な新規抗炎症性代謝物 (2010)
  • Inventor(s): 有田誠、井上将行、占部大介、増田功司、新井洋由
  • Industrial Property Rights Holder: 東京大学
  • Industrial Property Number: 2010-188939
  • Filing Date: 2010-08-25