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Genes/SNPs of lipid mediators and diseases

Planned Research

Project AreaMachineries of bioactive lipids in homeostasis and diseases
Project/Area Number 22116010
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionKyushu University

Principal Investigator

YUTAKA Kiyohara  九州大学, 医学(系)研究科(研究院), 教授 (80161602)

Co-Investigator(Kenkyū-buntansha) KUBO Michiaki  理化学研究所, 総合生命医科学研究センター, 副センター長 (30442958)
NINOMIYA Toshiharu  九州大学, 大学院医学研究院, 教授 (30571765)
HATA Jun  九州大学, 大学院医学研究院, 准教授 (00448432)
Project Period (FY) 2010-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥116,610,000 (Direct Cost: ¥89,700,000、Indirect Cost: ¥26,910,000)
Fiscal Year 2014: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2013: ¥23,400,000 (Direct Cost: ¥18,000,000、Indirect Cost: ¥5,400,000)
Fiscal Year 2012: ¥24,570,000 (Direct Cost: ¥18,900,000、Indirect Cost: ¥5,670,000)
Fiscal Year 2011: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2010: ¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
Keywords脂質メディエーター / 遺伝子多型 / エイコサペンタエン酸 / アラキドン酸 / ビタミンD / 心血管病 / 悪性腫瘍 / 慢性腎臓病 / 死亡 / コホート研究 / 一塩基多型 / 一塩基遺伝子多型 / 関連遺伝子 / 生活習慣病 / 代謝性疾患 / メタボリック・シンドローム / 肥満 / 疫学研究 / 脂肪酸分面 / エイコサセン酸 / 追跡調査 / 虚血性心疾患 / メタボリックシンドローム / 脂肪酸分画 / EPA/AA濃度比 / 1,25(OH)2ビタミンD / 高感度C反応性蛋白 / 総死亡率 / 心血管病死亡率
Outline of Final Research Achievements

We examined the associations of lipid mediators or their genetic polymorphysms with common diseases in inhabitants of Hisayama Town, Fukuoka. The association study of genetic polymorphisms and common diseases revealed that a polymorphism in PLA2G3 gene was associated with serum HDL cholesterol concentration, and a polymorphism in PA-PLA1 was correlated with body mass index. The cohort study in Hisayama demonstrated that a lower ratio of serum eicosapentaenoic acid to arachidonic acid was a risk factor for the development of coronary heart disease and death from malignant tumors, and that a decreased level of serum 1,25-dihydroxy-vitamin D was associated with an increased risk of chronic kidney disease.

Report

(6 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (221 results)

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article (136 results) (of which Peer Reviewed: 133 results,  Open Access: 4 results,  Acknowledgement Compliant: 6 results) Presentation (67 results) (of which Invited: 11 results) Book (18 results)

  • [Journal Article] Trends in the Incidence and Survival of Intracerebral Hemorrhage by its Location in a Japanese Community2014

    • Author(s)
      Gotoh S, Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Fukuhara M, Ikeda F, Shikata K, Kamouchi M, Kitazono T, Kiyohara Y
    • Journal Title

      Circulation Journal

      Volume: 78 Issue: 2 Pages: 403-409

    • DOI

      10.1253/circj.CJ-13-0811

    • NAID

      130003382214

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Serum 1,25-Dihydroxyvitamin D and the Development of Kidney Dysfunction in a Japanese Community2014

    • Author(s)
      Izumaru K, Ninomiya T, Nagata M, Usui T, Yoshida D, Yonemoto K, Fukuhara M, Tsuruya K, Kitazono T, Kiyohara Y
    • Journal Title

      Circulation Journal

      Volume: 78 Issue: 3 Pages: 732-737

    • DOI

      10.1253/circj.CJ-13-0422

    • NAID

      130003382240

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Non-high-density lipoprotein cholesterol and the development of coronary heart disease and stroke subtypes in a general Japanese population: the Hisayama Study.2014

    • Author(s)
      Imamura T, Doi Y, Ninomiya T, Hata J, Nagata M, Ikeda F, Mukai N, Hirakawa Y, Yoshida D, Fukuhara M, Kitazono T, Kiyohara Y
    • Journal Title

      Atherosclerosis

      Volume: 233 Issue: 2 Pages: 343-348

    • DOI

      10.1016/j.atherosclerosis.2014.01.005

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Milk and dairy consumption and risk of dementia in an elderly Japanese population: the Hisayama Study.2014

    • Author(s)
      Ozawa M, Ohara T, Ninomiya T, Hata J, Yoshida D, Mukai N, Nagata M, Uchida K, Shirota T, Kitazono T, Kiyohara Y
    • Journal Title

      J Am Geriatr Soc

      Volume: 62 Issue: 7 Pages: 1224-1230

    • DOI

      10.1111/jgs.12887

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A Low Ankle Brachial Index is Associated with an Increased Risk of Cardiovascular Disease: The Hisayama Study2014

    • Author(s)
      Kojima I, Ninomiya T, Hata J, Fukuhara M, Hirakawa Y, Mukai N, Yoshida D, Kitazono T, Kiyohara Y
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 21 Issue: 9 Pages: 966-973

    • DOI

      10.5551/jat.22608

    • NAID

      130004690937

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Midlife and late-life handgrip strength and risk of cause-specific death in a general Japanese population: the Hisayama Study.2014

    • Author(s)
      Kishimoto H, Hata J, Ninomiya T, Nemeth H, Hirakawa Y, Yoshida D, Kumagai S, Kitazono T, Kiyohara Y
    • Journal Title

      J Epidemiol Community Health

      Volume: 68 Issue: 7 Pages: 663-668

    • DOI

      10.1136/jech-2013-203611

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Alexithymia is associated with greater risk of chronic pain and negative affect and with lower life satisfaction in a general population: the Hisayama Study.2014

    • Author(s)
      Shibata M, Ninomiya T, Jensen MP, Anno K, Yonemoto K, Makino S, Iwaki R, Yamashiro K, Yoshida T, Imada Y, Kubo C, Kiyohara Y, Sudo N, Hosoi M.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 3 Pages: e90984-e90984

    • DOI

      10.1371/journal.pone.0090984

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thresholds of various glycemic measures for diagnosing diabetes based on prevalence of retinopathy in community-dwelling Japanese subjects: the Hisayama Study.2014

    • Author(s)
      Mukai N, Yasuda M, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M, Hotta T, Koga M, Nakamura U, Kang D, Kitazono T, Kiyohara Y.
    • Journal Title

      Cardiovasc Diabetol

      Volume: 13 Issue: 1 Pages: 45-45

    • DOI

      10.1186/1475-2840-13-45

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cardiovascular disease: the Hisayama Study.2013

    • Author(s)
      Ninomiya T, Nagata M, Hata J, Hirakawa Y, Ozawa M, Yoshida D, Ohara T, Kishimoto H, Mukai N, Fukuhara M, Kitazono T, Kiyohara Y.
    • Journal Title

      Atherosclerosis

      Volume: 231 Issue: 2 Pages: 261-267

    • DOI

      10.1016/j.atherosclerosis.2013.09.023

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Haemoglobin A1c even within non-diabetic level is a predictor of cardiovascular disease in a general Japanese population: the Hisayama Study.2013

    • Author(s)
      Ikeda F, Doi Y, Ninomiya T, Hirakawa Y, Mukai N, Hata J, Shikata K, Yoshida D, Matsumoto T, Kitazono T, Kiyohara Y.
    • Journal Title

      Cardiovasc Diabetol

      Volume: 12 Issue: 1 Pages: 164-164

    • DOI

      10.1186/1475-2840-12-164

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study.2013

    • Author(s)
      Sekita A, Arima H, Ninomiya T, Ohara T, Doi Y, Hirakawa Y, Fukuhara M, Hata J, Yonemoto K, Ga Y, Kitazono T, Kanba S, Kiyohara Y.
    • Journal Title

      BMC Public Health

      Volume: 13 Issue: 1 Pages: 862-862

    • DOI

      10.1186/1471-2458-13-862

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.2013

    • Author(s)
      Asano K, Matsumoto T, Umeno J, Hirano A, Esaki M, Hosono N, Matsui T, Kiyohara Y, Nakamura Y, Kubo M, Kitazono T.
    • Journal Title

      Inflamm Bowel Dis

      Volume: 19 Issue: 10 Pages: 2061-2068

    • DOI

      10.1097/mib.0b013e318298118e

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Secular trends in cardiovascular disease and its risk factors in Japanese: half-century data from the Hisayama Study (1961-2009).2013

    • Author(s)
      Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Gotoh S, Fukuhara M, Ikeda F, Shikata K, Yoshida D, Yonemoto K, Kamouchi M, Kitazono T, Kiyohara Y.
    • Journal Title

      Circulation

      Volume: 128 Issue: 11 Pages: 1198-1205

    • DOI

      10.1161/circulationaha.113.002424

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gender differences in the association between metabolic syndrome and periodontal disease: the Hisayama Study.2013

    • Author(s)
      Furuta M, Shimazaki Y, Takeshita T, Shibata Y, Akifusa S, Eshima N, Kiyohara Y, Ninomiya T, Hirakawa Y, Mukai N, Nagata M, Yamashita Y.
    • Journal Title

      J Clin Periodontol

      Volume: 40 Issue: 8 Pages: 743-752

    • DOI

      10.1111/jcpe.12119

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Magnesium intake decreases type 2 diabetes risk through the improvement of insulin resistance and inflammation: the Hisayama Study.2013

    • Author(s)
      Hata A, Doi Y, Ninomiya T, Mukai N, Hirakawa Y, Hata J, Ozawa M, Uchida K, Shirota T, Kitazono T, Kiyohara Y.
    • Journal Title

      Diabet Med

      Volume: 30 Issue: 12 Pages: 1487-1494

    • DOI

      10.1111/dme.12250

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Angiopoietin-Like Protein 2 Is Associated With Chronic Kidney Disease in a General Japanese Population2013

    • Author(s)
      Usui T, Ninomiya T, Nagata M, Takahashi O, Doi Y, Hata J, Fukuhara M, Kitazono T, Oike Y, Kiyohara Y.
    • Journal Title

      Circulation Journal

      Volume: 77 Issue: 9 Pages: 2311-2317

    • DOI

      10.1253/circj.CJ-12-1548

    • NAID

      10031191759

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Temporal trends in sudden unexpected death in a general population: the Hisayama Study.2013

    • Author(s)
      Nagata M, Ninomiya T, Doi Y, Hata J, Ikeda F, Mukai N, Tsuruya K, Oda Y, Kitazono T, Kiyohara Y.
    • Journal Title

      Am Heart J

      Volume: 165 Issue: 6 Pages: 932-938

    • DOI

      10.1016/j.ahj.2013.02.028

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] White-coat and masked hypertension are associated with carotid atherosclerosis in a general population: the Hisayama Study.2013

    • Author(s)
      Fukuhara M, Arima H, Ninomiya T, Hata J, Hirakawa Y, Doi Y, Yonemoto K, Mukai N, Nagata M, Ikeda F, Matsumura K, Kitazono T, Kiyohara Y.
    • Journal Title

      Stroke

      Volume: 44 Issue: 6 Pages: 1512-1517

    • DOI

      10.1161/strokeaha.111.000704

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: results from the Hisayama Study.2013

    • Author(s)
      Nakano T, Ninomiya T, Sumiyoshi S, Onimaru M, Fujii H, Itabe H, Nakashima Y, Sueishi K, Tsuruya K, Oda Y, Kitazono T, Kiyohara Y.
    • Journal Title

      Kidney Int

      Volume: 84 Issue: 2 Pages: 373-380

    • DOI

      10.1038/ki.2013.111

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary patterns and risk of dementia in an elderly Japanese population: the Hisayama Study.2013

    • Author(s)
      Ozawa M, Ninomiya T, Ohara T, Doi Y, Uchida K, Shirota T, Yonemoto K, Kitazono T, Kiyohara Y.
    • Journal Title

      Am J Clin Nutr

      Volume: 97 Issue: 5 Pages: 1076-1082

    • DOI

      10.3945/ajcn.112.045575

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Angiopoietin-like protein 2 and risk of type 2 diabetes in a general Japanese population: the Hisayama study.2013

    • Author(s)
      Doi Y, Mukai N(5番目), et al.
    • Journal Title

      Diabetes Care

      Volume: 36 Issue: 1 Pages: 98-100

    • DOI

      10.2337/dc12-0166

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cut-off values of fasting and post-load plasma glucose and HbA1c for predicting Type 2 diabetes in community-dwelling Japanese subjects2012

    • Author(s)
      Mukai N, Fukuhara M, Kiyohara Y(最後), 他5名
    • Journal Title

      the Hisayama Study

      Volume: 29 Issue: 1 Pages: 99-106

    • DOI

      10.1111/j.1464-5491.2011.03378.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two risk score models for predicting incident type 2 diabetes in Japanese.2012

    • Author(s)
      Doi Y, Mukai N(5番目), et al.
    • Journal Title

      Diabet Med

      Volume: 29 Issue: 1 Pages: 107-114

    • DOI

      10.1111/j.1464-5491.2011.03376.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary vitamin A intake and incidence of gastric cancer in a general Japanese population : the Hisayama Study2012

    • Author(s)
      Miyazaki M, Doi Y, Ikeda F, Ninomiya T, Hata J, Uchida K, Shirota T, Matsumoto T, Iida M, Kiyohara Y
    • Journal Title

      Gastric Cancer

      Volume: 15(2) Issue: 2 Pages: 162-169

    • DOI

      10.1007/s10120-011-0092-7

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Smoking cessation improves mortality in Japanese men: the Hisayama Study.2012

    • Author(s)
      Ikeda F (1番目), et al.
    • Journal Title

      Tob Control

      Volume: 21 Issue: 4 Pages: 416-421

    • DOI

      10.1136/tc.2010.039362

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence and Causes of Functional Disability in an Elderly General Population of Japanese: The Hisayama Study2012

    • Author(s)
      Yoshida D, Fukuhara M(5番目), Kiyohara Y(最後), 他5名
    • Journal Title

      Journal of Epidemiology

      Volume: 22 Issue: 3 Pages: 222-229

    • DOI

      10.2188/jea.JE20110083

    • NAID

      10030618141

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of lower range of prehypertension on cardiovascular events in a general population2012

    • Author(s)
      Fukuhara M, Kiyohara Y(最後), 他8名
    • Journal Title

      the Hisayama Study

      Volume: 30 Issue: 5 Pages: 893-900

    • DOI

      10.1097/hjh.0b013e328351d380

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optimal cutoff value of the serum pepsinogen level for prediction of gastric cancer incidence : the Hisayama Study2012

    • Author(s)
      Shikata K., Ninomiya T., Yonemoto K., 他8名
    • Journal Title

      Scandinavian Journal of Gastroenterology

      Volume: 47(6) Issue: 6 Pages: 669-675

    • DOI

      10.3109/00365521.2012.658855

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Insulin Resistance and the Development of Cardiovascular Disease in a Japanese Community: the Hisayama Study2012

    • Author(s)
      Gotoh S. et. al.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 11 Pages: 977-985

    • DOI

      10.5551/jat.13698

    • NAID

      130004444559

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2012 Annual Research Report
  • [Journal Article] Self-reported dietary intake of potassium, calcium, and magnesium and risk of dementia in the Japanese: the Hisayama Study2012

    • Author(s)
      Ozawa, M. Ninomiya, T. Ohara, T. Hirakawa, Y. Doi, Y. Hata, J. Uchida, K. Shirota, T. Kitazono, T. Kiyohara, Y.
    • Journal Title

      J Am Geriatr Soc

      Volume: 60 Issue: 8 Pages: 1515-1520

    • DOI

      10.1111/j.1532-5415.2012.04061.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between glucose tolerance level and cancer death in a general Japanese population: the Hisayama Study.2012

    • Author(s)
      Hirakawa Y, Mukai N(3番目), et al.
    • Journal Title

      Am J Epidemiol

      Volume: 176 Issue: 10 Pages: 856-864

    • DOI

      10.1093/aje/kws178

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association study of susceptibility genes for late-onset Alzheimer’s disease in the Japanese population2012

    • Author(s)
      Ohara T (1番目), et al.
    • Journal Title

      Psychiatr Genet

      Volume: 22 Issue: 6 Pages: 290-293

    • DOI

      10.1097/ypg.0b013e3283586215

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.2012

    • Author(s)
      Hirota T
    • Journal Title

      Nat Genet

      Volume: 44 Issue: 11 Pages: 1222-6

    • DOI

      10.1038/ng.2438

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations2012

    • Author(s)
      Okada, Y. et. al.
    • Journal Title

      Nat Genet

      Volume: 44 Issue: 8 Pages: 904-909

    • DOI

      10.1038/ng.2352

    • Related Report
      2012 Annual Research Report
  • [Journal Article] A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population2012

    • Author(s)
      Shiraishi K, Kunitoh H, Daigo Y, Takahashi A, Goto K, Sakamoto H, Ohnami S, Shimada Y, Ashikawa K, Saito A, Watanabe S, Tsuta K, Kamatani N, Yoshida T, Nakamura Y, Yokota J, Kubo M, Kohno T
    • Journal Title

      Nature Genetics

      Volume: 44 Issue: 8 Pages: 900-903

    • DOI

      10.1038/ng.2353

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.2012

    • Author(s)
      Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, Aoki M, Hosono N, Kubo M, Miya F, Arai Y, Takahashi H, Shirakihara T, Nagasaki M, Shibuya T, Nakano K, Watanabe-Makino K, Tanaka H, Nakamura H, Kusuda J, Ojima H, Shimada K, Okusaka T, Ueno M, Shigekawa Y, Kawakami Y, Arihiro K, Ohdan H, Gotoh K, Ishikawa O, Ariizumi S, Yamamoto M, Yamada T, Chayama K, Kosuge T, Yamaue H, Kamatani N, Miyano S, Nakagama H, Nakamura Y, Tsunoda T, Shibata T, Nakagawa H
    • Journal Title

      Nature Genetic

      Volume: 44 Issue: 7 Pages: 760-764

    • DOI

      10.1038/ng.2291

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study identifies three new risk loci for Kawasaki disease2012

    • Author(s)
      Onouchi Y, et al
    • Journal Title

      Nat Genet

      Volume: 44 Issue: 5 Pages: 517-521

    • DOI

      10.1038/ng.2220

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population2012

    • Author(s)
      Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl EA, Kurreeman FA, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen PK, Padyukov L, Worthington J, Siminovitch KA, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M, Nakamura Y, Kamatani N, Mimori T, Plenge RM, Yamanaka H, Momohara S, Yamada R, Matsuda F, Yamamoto K.
    • Journal Title

      Nat Genet.

      Volume: (in press) Issue: 5 Pages: 511-6

    • DOI

      10.1038/ng.2231

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.2012

    • Author(s)
      Tanikawa C, Urabe Y, Matsuo K, Kubo M, Takahashi A, Ito H, Tajima K, Kamatani N, Nakamura Y, Matsuda K.
    • Journal Title

      Nat Genet.

      Volume: 44 Issue: 4 Pages: 430-434

    • DOI

      10.1038/ng.1109

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese2012

    • Author(s)
      赤松秀輔, 他
    • Journal Title

      Nature Genetics

      Volume: 44 Issue: 4 Pages: 426-429

    • DOI

      10.1038/ng.1104

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations2012

    • Author(s)
      Okada Y. et. al.
    • Journal Title

      Nat Genet

      Volume: 44 Issue: 3 Pages: 302

    • DOI

      10.1038/ng.1086

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
  • [Journal Article] A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese2012

    • Author(s)
      岡田随象
    • Journal Title

      PLoS Genetics

      Volume: (掲載確定) Issue: 1 Pages: 1002455-1002455

    • DOI

      10.1371/journal.pgen.1002455

    • NAID

      120005906866

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development and Function of Invariant Natural Killer T cells Producing TH2- and TH17-cytokines2012

    • Author(s)
      Watarai H, Sekine-Kondo E, Shigeura T, Motomura Y, Yasuda T, Satoh R, Yoshida H, Kubo M, Kawamoto H, Koseki H, Taniguchi M
    • Journal Title

      PLoS Biol

      Volume: 10 Issue: 2 Pages: e1001255-e1001255

    • DOI

      10.1371/journal.pbio.1001255

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness2012

    • Author(s)
      Sawaguchi, M.
    • Journal Title

      J.Immunol.

      Volume: 188 Issue: 4 Pages: 1809-1818

    • DOI

      10.4049/jimmunol.1101746

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients2012

    • Author(s)
      Kiyotani, K., et.al.
    • Journal Title

      Breast Cancer Res Treat

      Volume: 131(1) Issue: 1 Pages: 137-45

    • DOI

      10.1007/s10549-011-1777-7

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] N-terminal pro-brain natriuretic peptide and risk of cardiovascular events in a Japanese community2011

    • Author(s)
      Doi Y, Fukuhara M(7番目), Kiyohara Y(最後), 他6名
    • Journal Title

      the Hisayama Study

      Volume: 31 Issue: 12 Pages: 2997-3003

    • DOI

      10.1161/atvbaha.111.223669

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combined effects of smoking and hypercholesterolemia on the risk of stroke and coronary heart disease in Japanese2011

    • Author(s)
      Hata J, Fukuhara M(4番目), Kiyohara Y(最後), 他6名
    • Journal Title

      the Hisayama Study

      Volume: 31 Issue: 5 Pages: 477-484

    • DOI

      10.1159/000324392

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of Alzheimer disease pathology with abnormal lipid metabolism : the Hisayama Study2011

    • Author(s)
      Matsuzaki, T., et.al.
    • Journal Title

      Neurology

      Volume: 77(11) Issue: 11 Pages: 1068-75

    • DOI

      10.1212/wnl.0b013e31822e145d

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Glucose tolerance status and risk of dementia in the community : the Hisayama Study2011

    • Author(s)
      Ohara, T., et.al.
    • Journal Title

      Neurology

      Volume: 77(12) Issue: 12 Pages: 1126-34

    • DOI

      10.1212/wnl.0b013e31822f0435

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Apolipoprotein genotype for prediction of Alzheimer's disease in older Japanese : the Hisayama Study2011

    • Author(s)
      Ohara, T., et.al.
    • Journal Title

      J Am Geriatr Soc

      Volume: 59(6) Issue: 6 Pages: 1074-9

    • DOI

      10.1111/j.1532-5415.2011.03405.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Albuminuria as a risk factor for peripheral arterial disease in a general population: the Hisayama Study2011

    • Author(s)
      Usui, T., et.al.
    • Journal Title

      J Atheroscler Thromb

      Volume: 18(8) Pages: 705-12

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] White blood cell count and risk of gastric cancer incidence in a general Japanese population : the Hisayama Study2011

    • Author(s)
      Iida, M., et.al.
    • Journal Title

      Am J Epidemiol

      Volume: 175(6) Issue: 6 Pages: 504-10

    • DOI

      10.1093/aje/kwr345

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effectiveness of the salivary occult blood test as a screening method for periodontal status2011

    • Author(s)
      Shimazaki, Y., et.al.
    • Journal Title

      J Periodontol

      Volume: 82(4) Issue: 4 Pages: 581-7

    • DOI

      10.1902/jop.2010.100304

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nine-year incidence and risk factors for retinal vein occlusion in a general Japanese population : the Hisayama Study2011

    • Author(s)
      Arakawa, S., et.al.
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 52(8) Issue: 8 Pages: 5905-9

    • DOI

      10.1167/iovs.11-7775

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High serum bilirubin levels and diabetic retinopathy : the Hisayama Study2011

    • Author(s)
      Yasuda, M., et.al.
    • Journal Title

      Ophthalmology

      Volume: 118(7) Issue: 7 Pages: 1423-8

    • DOI

      10.1016/j.ophtha.2010.12.009

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common variant s in a novel gene, FONG on chromosome 2q33. 1 confer risk of osteoporosis in Japanese2011

    • Author(s)
      Kou I, Takahashi A, Urano T, Fukui N, Ito H, Ozaki K, Tanaka T, Hosoi T, Shiraki M, Inoue S, Nakamura Y, Kamatani N, Kubo M, Mori S, Ikegawa S
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 5 Pages: e19641-e19641

    • DOI

      10.1371/journal.pone.0019641

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis : case-control studies2011

    • Author(s)
      Hirota, T., et.al.
    • Journal Title

      PLoS One

      Volume: 6(11) Issue: 11 Pages: e26987-e26987

    • DOI

      10.1371/journal.pone.0026987

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of nine novel loci associated with white blood cell subtypes in a Japanese population2011

    • Author(s)
      岡田随象
    • Journal Title

      PLoS Genetics

      Volume: 7 Issue: 6 Pages: e1002067-e1002067

    • DOI

      10.1371/journal.pgen.1002067

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple loci are associated with white blood cell phenotypes2011

    • Author(s)
      Nalls, M.A., et.al.
    • Journal Title

      PLoS Genet

      Volume: 7(6) Issue: 6 Pages: e1002113-e1002113

    • DOI

      10.1371/journal.pgen.1002113

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells2011

    • Author(s)
      Motomura, Y., et al
    • Journal Title

      Nature Immunology

      Volume: 12 Issue: 5 Pages: 450-459

    • DOI

      10.1038/ni.2020

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis2011

    • Author(s)
      Takahashi, Y., et.al.
    • Journal Title

      Nat Genet

      Volume: 43(12) Issue: 12 Pages: 1237-40

    • DOI

      10.1038/ng.974

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers2011

    • Author(s)
      Miki D, Ochi H, Hayes CN, Abe H, Yoshima T, Aikata H, Ikeda K, KumadaH, Toyota J, Morizono T, Tsunoda T, Kubo M, Nakamura Y, Kamatani N, Chayama K
    • Journal Title

      Nat Genet

      Volume: 43 Issue: 8 Pages: 797-800

    • DOI

      10.1038/ng.876

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population2011

    • Author(s)
      Hirota, T., et.al.
    • Journal Title

      Nat Genet

      Volume: 43(9) Issue: 9 Pages: 893-6

    • DOI

      10.1038/ng.887

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population2011

    • Author(s)
      Arakawa, S., et.al.
    • Journal Title

      Nat Genet

      Volume: 43(10) Issue: 10 Pages: 1001-4

    • DOI

      10.1038/ng.938

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state2011

    • Author(s)
      Abe H, Hayes CN, Ochi H, Tsuge M, Miki D, Hiraga N, Imamura M, Takahashi S, Kubo M, Nakamura Y, Kamatani N, Chayama K
    • Journal Title

      J Med Virol

      Volume: 83 Issue: 9 Pages: 1597-1607

    • DOI

      10.1002/jmv.22158

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IL28 variationaffects expression of interferonstimulated genes and peg-interferonand ribavirin the rapy2011

    • Author(s)
      Abe H, Hayes CN, Ochi H, Maekawa T, Tsuge M, Miki D, Mitsui F, Hiraga N, Imamura M, Takahashi S, Kubo M, Nakamura Y, Chayama K
    • Journal Title

      J Hepatol

      Volume: 54 Issue: 6 Pages: 1094-1101

    • DOI

      10.1016/j.jhep.2010.09.019

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IL-28B predicts response to chronic hepatitis Ctherapy-fine-mapping and replication study in Asian populations2011

    • Author(s)
      Ochi H, Maekawa T, Abe H, Hayashida Y, Nakano R, Imamura M, Hiraga N, Kawakami Y, Aimitsu S, Kao JH, Kubo M, Tsunoda T, Kumada H, Nakamura Y, HayesCN, Chayama K
    • Journal Title

      J Gen Virol

      Volume: 92 Issue: 5 Pages: 1071-1081

    • DOI

      10.1099/vir.0.029124-0

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis2011

    • Author(s)
      Umeno, J., et.al.
    • Journal Title

      Inflamm Bowel Dis

      Volume: 17(12) Issue: 12 Pages: 2407-15

    • DOI

      10.1002/ibd.21651

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies HLA-A^*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population2011

    • Author(s)
      Ozeki T, et al
    • Journal Title

      Hum Mol Genet

      Volume: 20 Issue: 5 Pages: 1034-41

    • DOI

      10.1093/hmg/ddq537

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus2011

    • Author(s)
      Okada, Y., et.al.
    • Journal Title

      Hum Mol Genet

      Volume: 20(6) Issue: 6 Pages: 1224-31

    • DOI

      10.1093/hmg/ddq551

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.2011

    • Author(s)
      Iida A
    • Journal Title

      Hum Mol Genet

      Volume: 20 Issue: 18 Pages: 3684-3692

    • DOI

      10.1093/hmg/ddr268

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PlatinumCNV : a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data2011

    • Author(s)
      Kumasaka, N., et.al.
    • Journal Title

      Genet Epidemiol

      Volume: 35(8) Issue: 8 Pages: 831-44

    • DOI

      10.1002/gepi.20633

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study on bipolar disorder in the Bulgarian population2011

    • Author(s)
      Yosifova, A., et.al.
    • Journal Title

      Genes Brain Behav

      Volume: 10(7) Issue: 7 Pages: 789-97

    • DOI

      10.1111/j.1601-183x.2011.00721.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Body mass index and stroke incidence in a Japanese community : the Hisayama Study.2011

    • Author(s)
      Yonemoto K, et al.
    • Journal Title

      Hypertens Res

      Volume: 34 Pages: 274-279

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combined effects of smoking and hypercholesterolemia on the risk of stroke and coronary heart disease in Japanese : the Hisayama Study.2011

    • Author(s)
      Hata J, et al.
    • Journal Title

      Neurology

      Volume: 31 Pages: 477-484

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combined Effects of Smoking and Hypercholesterolemia on the Risk of Stroke and Coronary Heart Disease in Japanese : the Hisayama Study.2011

    • Author(s)
      Hata J, et al
    • Journal Title

      Cerebrovasc Dis

      Volume: 31 Pages: 477-484

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Insulin resistance is associated with the pathology of Alzheimer disease : the Hisayama Study.2011

    • Author(s)
      Yonemoto K, et al
    • Journal Title

      Hypertens Res

      Volume: 34 Pages: 274-279

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.2011

    • Author(s)
      Okada Y, et al
    • Journal Title

      Hum Mol Genet

      Volume: 20 Pages: 1224-1231

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.2011

    • Author(s)
      Ozeki T, et al
    • Journal Title

      Hum Mol Genet

      Volume: 20 Pages: 1034-1041

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.2011

    • Author(s)
      Kawaoka T, et al
    • Journal Title

      J Hepatol

      Volume: 54 Pages: 408-414

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.2011

    • Author(s)
      Aoki A, et al
    • Journal Title

      J Hum Genet

      Volume: 56 Pages: 47-51

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.2011

    • Author(s)
      Kochi Y, et al
    • Journal Title

      Ann Rheum Dis

      Volume: 70 Pages: 512-515

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.2011

    • Author(s)
      Chung S, et al
    • Journal Title

      Cancer Sci

      Volume: 102 Pages: 245-252

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effectiveness of the salivary occult blood test as a screening method for periodontal status.2011

    • Author(s)
      Shimazaki Y, et al.
    • Journal Title

      J Periodontol

      Volume: 82 Pages: 581-587

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Population attributable numbers and fractions of deaths due to smoking a pooled analysis of 180,000 Japanese.2011

    • Author(s)
      Murakami Y, et al
    • Journal Title

      Prev Med

      Volume: 52 Pages: 764-770

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prevention of type 2 diabetes in a primary healthcare setting : Three-year results of lifestyle intervention in Japanese subjects with impaired glucose tolerance.2011

    • Author(s)
      Sakane N, et al
    • Journal Title

      BMC Public Health

      Volume: 11 Pages: 40-40

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circulating resistin is increased with decreasing renal function in a general Japanese population : the Hisayama Study.2010

    • Author(s)
      Kawamura R, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 25 Pages: 3236-3240

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.2010

    • Author(s)
      Matsushita T, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 19 Pages: 1137-1146

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.2010

    • Author(s)
      Matsushita T, et al
    • Journal Title

      J Hum Genet

      Volume: 20 Pages: 473-476

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The, effect of metabolic syndrome defined by various criteria on the development of ischemic stroke subtypes in a general Japanese population.2010

    • Author(s)
      Hata J, et al
    • Journal Title

      Atherosclerosis

      Volume: 210 Pages: 249-255

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Trends in the prevalence of chronic kidney disease and its risk factors in a general Japanese population : the Hisayama Study.2010

    • Author(s)
      Nagata M, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 25 Pages: 2557-2564

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] QT interval prolongation and the risks of stroke and coronary heart disease in a general Japanese population : the Hisayama Study.2010

    • Author(s)
      Maebuchi D, et al.
    • Journal Title

      Hypertens Res

      Volume: 33 Pages: 916-921

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Trends in prevalence of Alzheimer's disease and vascular dementia in a Japanese community : the Hisayama Study.2010

    • Author(s)
      Sekita A, et al.
    • Journal Title

      Acta Psychiatr Scand

      Volume: 122 Pages: 319-325

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Variation in TP63 is associated with lung adenocarcinoma suscepti-bility in Japanese and Korean populations.2010

    • Author(s)
      Miki D, et al
    • Journal Title

      Nat Genet

      Volume: 42 Pages: 893-896

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.2010

    • Author(s)
      Fujimoto A, et al
    • Journal Title

      Nat Genet

      Volume: 42 Pages: 931-936

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.2010

    • Author(s)
      Yoon KA, et al
    • Journal Title

      Hum Mol Genet

      Volume: 20 Pages: 4948-54

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.2010

    • Author(s)
      Ingle JN, et al
    • Journal Title

      J Clin Oncol

      Volume: 28 Pages: 4674-4682

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.2010

    • Author(s)
      Cha PC, et al
    • Journal Title

      Hum Mol Genet

      Volume: 19 Pages: 4735-4744

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.2010

    • Author(s)
      Yamauchi T, et al
    • Journal Title

      Nat Genet

      Volume: 42 Pages: 864-868

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression.2010

    • Author(s)
      Akamatsu S, et al
    • Journal Title

      Hum Mol Genet

      Volume: 19 Pages: 4265-4272

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.2010

    • Author(s)
      Nakashima M, et al
    • Journal Title

      Nat Genet

      Volume: 42 Pages: 768-771

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study of pancreatic cancer in Japanese population.2010

    • Author(s)
      Low SK, et al
    • Journal Title

      PLoS One

      Volume: 5

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of new HLA-B*3505 genotyping method using Invader assay.2010

    • Author(s)
      Hosono N, et al
    • Journal Title

      Pharmacogenet Genomics

      Volume: 20 Pages: 630-633

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.2010

    • Author(s)
      Takata R, et al
    • Journal Title

      Nat Genet

      Volume: 42 Pages: 751-754

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic polymorphisms in the Organic Cation Transporter 1, OCT1, in Chinese and Japanese populations, exhibit altered function.2010

    • Author(s)
      Chen L, et al
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 335 Pages: 42-50

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ITPA polymorphism affects Ribavirin-induced anemia and outcome of therapy-a genome-wide study of Japanese HCV patients.2010

    • Author(s)
      Ochi H, et al
    • Journal Title

      Gastroenterology

      Volume: 139 Pages: 1190-1197

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.2010

    • Author(s)
      Koriyama H, et al
    • Journal Title

      J Atheroscler Thromb

      Volume: 17 Pages: 1054-1062

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.2010

    • Author(s)
      Uno S, et al
    • Journal Title

      Nat Genet

      Volume: 42 Pages: 707-710

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.2010

    • Author(s)
      Abe H, et al
    • Journal Title

      J Hepatol

      Volume: 53 Pages: 439-443

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lessons for pharmacogenomics studies : association study between CYP2D6 genotype and tamoxifen response.2010

    • Author(s)
      Kiyotani K, et al
    • Journal Title

      Pharmacogenet Genomics

      Volume: 20 Pages: 565-568

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes.2010

    • Author(s)
      Kumasaka N, et al
    • Journal Title

      J Hum Genet

      Volume: 55 Pages: 525-533

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Making a haplotype catalog with estimated frequencies based on SNP homozygotes.2010

    • Author(s)
      Yamaguchi-Kabata Y, et al
    • Journal Title

      J Hum Genet

      Volume: 55 Pages: 500-506

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.2010

    • Author(s)
      Okada Y, et al
    • Journal Title

      Ann Rheum Dis

      Volume: 69 Pages: 1569-1570

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.2010

    • Author(s)
      Kochi Y, et al
    • Journal Title

      Nat Genet

      Volume: 42 Pages: 515-519

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.2010

    • Author(s)
      Ramamoorthy A, et al
    • Journal Title

      Pharmacogenet Genomics

      Volume: 20 Pages: 451-454

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.2010

    • Author(s)
      Prescott NJ, et al
    • Journal Title

      Hum Mol Genet

      Volume: 19 Pages: 1828-1839

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study in 19,633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.2010

    • Author(s)
      Okada Y, et al
    • Journal Title

      Hum Mol Genet

      Volume: 19 Pages: 2303-2312

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.2010

    • Author(s)
      Okada Y, et al
    • Journal Title

      Hum Mol Genet

      Volume: 19 Pages: 2079-2085

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence and systemic risk factors of retinal vein occlusion in a general Japanese population : the Hisayama Study.2010

    • Author(s)
      Yasuda M, et al.
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 51 Pages: 3205-3209

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Integration of data from NIPPON DATA80/90 and National Nutrition Survey in Japan : for cohort studies of representative Japanese on nutrition2010

    • Author(s)
      Okuda N, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Total energy intake and intake of three major nutrients by body mass index in Japan : NIPPON DATA80 and NIPPON DATA90.2010

    • Author(s)
      Yoshita K, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary salt intake and blood pressure in a representative Japanese population : baseline analyses of NIPPON DATA80.2010

    • Author(s)
      Miura K, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Variation in TP63 is associated with lung adenocarcinoma suscepti-bility in Japanese and Korean populations.2010

    • Author(s)
      Miki D, et al
    • Journal Title

      J Epidemiol

      Volume: 20 Pages: 893-896

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Protein intakes and serum albumin levels in a Japanese general population : NIPPON DATA90.2010

    • Author(s)
      Watanabe M, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between protein intake and renal function in a Japanese general population : NIPPON DATA90.2010

    • Author(s)
      Higashiyama A, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fatty acids intakes and serum lipid profiles : NIPPON DATA90 and the national nutrition monitoring.2010

    • Author(s)
      Nakamura Y, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Calcium intake and associated factors in a general Japanese population : baseline data of NIPPON DATA80/90 and the National Nutrition Survey.2010

    • Author(s)
      Higashiguchi M, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Iron intake and associated factors in general Japanese population : NIPPON DATA80, NIPPON DATA90 and national nutrition monitoring.2010

    • Author(s)
      Turin TC, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary intake of potassium and associated dietary factors among representative samples of Japanese general population : NIPPON DATA 80/90.2010

    • Author(s)
      Turin TC, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between food group intake and serum total cholesterol in the Japanese population : NIPPON DATA 80/90.2010

    • Author(s)
      Kondo I, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of the National Nutritional Survey in Japan estimated individual-based nutritional data and NIPPON DATA80 food frequency questionnaires.2010

    • Author(s)
      Nakamura Y, et al
    • Journal Title

      J Epidemiol

      Volume: 20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Population attributable fraction of smoking and metabolic syndrome on cardiovascular disease mortality in Japan : a 15-year follow up of NIPPON DATA90.2010

    • Author(s)
      Takashima N, et al
    • Journal Title

      NBMC Public Health

      Volume: 3 Pages: 306-306

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality : an individual participant meta-analysis.2010

    • Author(s)
      Emerging Risk Factors Collaboration, et al
    • Journal Title

      Lancet

      Volume: 375 Pages: 132-140

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease : a collaborative meta-analysis of 102 prospective studies.2010

    • Author(s)
      Emerging Risk Factors Collaboration
    • Journal Title

      Lancet

      Volume: 375 Pages: 2215-2222

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Insulin resistance is associated with the pathology of Alzheimer disease : the Hisayama Study.2010

    • Author(s)
      Matsuzaki T, et al
    • Journal Title

      Neurology

      Volume: 75 Pages: 764-770

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies.2010

    • Author(s)
      Emerging Risk Factors Collaboration
    • Journal Title

      Int J Epidemiol

      Volume: 39 Pages: 1345-1359

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 広島宣言特別企画シンポジウム:予防(シンポジウム)2015

    • Author(s)
      清原 裕
    • Organizer
      第40回日本脳卒中学会総会
    • Place of Presentation
      広島市
    • Year and Date
      2015-03-26
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Association between the ratio of serum EPA to AA and cause-specific mortality in a general Japanese population: the Hisayama Study2015

    • Author(s)
      Nagata M, Ninomiya T, Hata J, Kiyohara Y
    • Organizer
      6th International Conference on Phosphlipase A2 and Lipid Mediators
    • Place of Presentation
      東京都
    • Year and Date
      2015-02-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 変貌する日本人の生活習慣病の現状と課題:久山町研究(特別講演)2014

    • Author(s)
      清原 裕
    • Organizer
      第61回日本臨床検査医学会学術集会
    • Place of Presentation
      福岡市
    • Year and Date
      2014-11-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 糖尿病と癌に関する臨床疫学のエビデンス(特別講演)2014

    • Author(s)
      清原 裕
    • Organizer
      第3回日本くすりと糖尿病学会学術集会
    • Place of Presentation
      福岡市
    • Year and Date
      2014-11-03
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 日本人の生活習慣病と循環器病(教育講演)2014

    • Author(s)
      清原 裕
    • Organizer
      第21回日本未病システム学会学術総会
    • Place of Presentation
      豊中市
    • Year and Date
      2014-11-01
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 肥満症と心血管病(シンポジウム)2014

    • Author(s)
      清原 裕
    • Organizer
      第35回日本肥満学会
    • Place of Presentation
      宮崎市
    • Year and Date
      2014-10-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 久山町研究―継続と発展の歴史(特別企画)2014

    • Author(s)
      清原 裕
    • Organizer
      第62回日本心臓病学会学術集会
    • Place of Presentation
      仙台市
    • Year and Date
      2014-09-27
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 生活習慣病と認知症:久山町研究(記念講演)2014

    • Author(s)
      清原 裕
    • Organizer
      第55回日本人間ドック学会学術大会
    • Place of Presentation
      福岡市
    • Year and Date
      2014-09-04
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 血管性認知症の最先端2012

    • Author(s)
      清原 裕
    • Organizer
      第31回日本認知症学会学術集会
    • Place of Presentation
      筑波氏
    • Year and Date
      2012-10-26
    • Related Report
      2012 Annual Research Report
  • [Presentation] 肥満症と動脈硬化2012

    • Author(s)
      清原 裕
    • Organizer
      第33回日本肥満学会
    • Place of Presentation
      京都市
    • Year and Date
      2012-10-11
    • Related Report
      2012 Annual Research Report
  • [Presentation] 疫学的エビデンスに基づいた提言2012

    • Author(s)
      清原 裕
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2012-09-20
    • Related Report
      2012 Annual Research Report
  • [Presentation] 糖尿病と認知症:久山町研究2012

    • Author(s)
      清原 裕
    • Organizer
      第2回日本認知症予防学会学術集会
    • Place of Presentation
      北九州市
    • Year and Date
      2012-09-09
    • Related Report
      2012 Annual Research Report
  • [Presentation] 心血管病の時代的変遷と今日の課題:久山町研究2012

    • Author(s)
      清原 裕
    • Organizer
      第18回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      埼玉市
    • Year and Date
      2012-07-14
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヘリコバクター感染症と胃癌のコホート研究2012

    • Author(s)
      清原 裕
    • Organizer
      第18回日本ヘリコバクター学会学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2012-06-29
    • Related Report
      2012 Annual Research Report
  • [Presentation] 地域住民における高血圧の実態:久山町研究の最新情報より2012

    • Author(s)
      清原 裕
    • Organizer
      日本高血圧学会第1回日本臨床高血圧フォーラム
    • Place of Presentation
      豊中市
    • Year and Date
      2012-05-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脳卒中発症予防のためのrisk管理~best medical treatment を目指して~2012

    • Author(s)
      清原 裕
    • Organizer
      第37回日本脳卒中学会総会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-04-27
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生活習慣病の危険因子:久山町研究2011

    • Author(s)
      清原裕
    • Organizer
      第18回日本未病システム学会学術総会
    • Place of Presentation
      名古屋市(招待講演)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 糖尿病と認知症の疫学:久山町研究2011

    • Author(s)
      清原裕
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京都(招待講演)
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高血圧とメタボリックシンドロームの疫学2011

    • Author(s)
      清原裕
    • Organizer
      第34回日本高血圧学会総会
    • Place of Presentation
      宇都宮市(招待講演)
    • Year and Date
      2011-10-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 変貌する日本人の生活習慣病の現状と課題:久山町研究2011

    • Author(s)
      清原裕
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京都(招待講演)
    • Year and Date
      2011-10-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 日本人におけるエビデンス構築の意義:Hisayama Studyを通して2011

    • Author(s)
      清原裕
    • Organizer
      第54回日本歯周病学会秋季学術大会
    • Place of Presentation
      下関市(招待講演)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Secular trends in hypertension and risk of stroke : the Hisayama Study2011

    • Author(s)
      Kiyohara Y
    • Organizer
      第43回日本動脈硬化学会総会
    • Place of Presentation
      札幌市(招待講演)
    • Year and Date
      2011-07-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高齢者における脳血管疾患を考慮した脂質管理2011

    • Author(s)
      清原裕
    • Organizer
      第27回日本老年学会総会
    • Place of Presentation
      東京都(招待講演)
    • Year and Date
      2011-06-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 変貌する心血管病の現状と課題:久山町研究2011

    • Author(s)
      清原裕
    • Organizer
      第47回日本循環器病予防学会・日本循環器管理研究協議会総会
    • Place of Presentation
      福岡市(招待講演)
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 認知症のコホート研究:久山町研究2011

    • Author(s)
      清原裕
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋市(招待講演)
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] コホート研究の実践:久山町研究2011

    • Author(s)
      清原裕
    • Organizer
      第39回日本血管外科学会学術総会
    • Place of Presentation
      沖縄県宜野湾市(招待講演)
    • Year and Date
      2011-04-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 日本人の心血管病のリスクを考える:久山町研究2011

    • Author(s)
      清原裕
    • Organizer
      第39回日本血管外科学会学術総会
    • Place of Presentation
      沖縄県宜野湾市(招待講演)
    • Year and Date
      2011-04-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 糖尿病と動脈硬化:久山町研究2011

    • Author(s)
      土井康文, 他
    • Organizer
      第45回糖尿病学の進歩
    • Place of Presentation
      福岡市
    • Year and Date
      2011-02-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域一般住民における余暇時の身体活動量と死亡の関係:久山町研究2011

    • Author(s)
      岸本裕代, 他
    • Organizer
      第21回日本疫学会学術総会
    • Place of Presentation
      札幌市
    • Year and Date
      2011-01-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 将来の胃癌発症予測のための血清ペプシノゲンのカットオフ値の検討:久山町研究2011

    • Author(s)
      志方健太郎, 他
    • Organizer
      第21回日本疫学会学術総会
    • Place of Presentation
      札幌市
    • Year and Date
      2011-01-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Albuminuria as a risk factor for peripheral arterial disease in a general japanese population : the Hisayama Study.2010

    • Author(s)
      Usui T, et al
    • Organizer
      The 43rd annual meeting and scientific exposition of american society of nephrology
    • Place of Presentation
      Denver, USA
    • Year and Date
      2010-11-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Proteinuria and kidney function independently predict cardiovascular outcomes : pooled analysis of 7 cohort studies2010

    • Author(s)
      Nagata M, et al
    • Organizer
      The 43rd annual meeting and scientific exposition of american society of nephrology
    • Place of Presentation
      Denver, USA
    • Year and Date
      2010-11-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 日本人の生活習慣病の実態と課題:久山町研究2010

    • Author(s)
      清原裕
    • Organizer
      第3回日本健康医療学会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域での保健活動による高血圧管理の取り組み:久山町研究と保健活動をとおして2010

    • Author(s)
      角森輝美, 他
    • Organizer
      第33回日本高血圧学会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-10-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高齢者社会における高血圧管理のあり方:久山町研究2010

    • Author(s)
      二宮利治, 他
    • Organizer
      第33回日本高血圧学会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-10-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 将来の胃癌発症予測のための血清ペプシノゲン値のカットオフ値の検討:久山町研究2010

    • Author(s)
      志方健太郎, 他
    • Organizer
      第52回日本消化器病学会大会2010
    • Place of Presentation
      横浜市
    • Year and Date
      2010-10-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肝機能障害が糖尿病および心血管病の発症に及ぼす影響2010

    • Author(s)
      土井康文, 他
    • Organizer
      第14回日本肝臓学会大会JDDW2010
    • Place of Presentation
      横浜市
    • Year and Date
      2010-10-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] Impact of midlife and late-life blood pressure on the development of dementia in Japanese elderly : the Hisayama Study.2010

    • Author(s)
      Ninomiya T, et al
    • Organizer
      The 23rd scientific meeting of the international society of hypertention
    • Place of Presentation
      Vancouver Canada
    • Year and Date
      2010-09-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] The impact of blood pressure on cardiovascular events in a general population : the Hisayama Study.2010

    • Author(s)
      Fukuhara M, et al
    • Organizer
      The 23rd scientific meeting of the international society of hypertention
    • Place of Presentation
      Vancouver Canada
    • Year and Date
      2010-09-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 日本人の生活習慣病の実態と課題:久山町研究2010

    • Author(s)
      清原裕
    • Organizer
      第36回福岡県栄養改善学会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域コホート研究:久山町研究2010

    • Author(s)
      岸本裕代, 他
    • Organizer
      第65回日本体力医学会大会
    • Place of Presentation
      千葉市
    • Year and Date
      2010-09-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新たなバイオマーカーと虚血性心疾患の発症リスク:久山町研究2010

    • Author(s)
      土井康文, 他
    • Organizer
      第58回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] High serum bilirubin levels and diabetic retinopathy : the Hisayama Study.2010

    • Author(s)
      Yasuda M, et al
    • Organizer
      The third joint meeting of China-Korea-Japan ophthalmologists
    • Place of Presentation
      Beijing China
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] Prevalence of myopic macular degeneration in a Japanese population : the Hisayama Study.2010

    • Author(s)
      Asakuma T, et al
    • Organizer
      The third joint meeting of China-Korea-Japan ophthalmologists
    • Place of Presentation
      Beijing China
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 栄養と生活習慣病:久山町研究2010

    • Author(s)
      清原裕
    • Organizer
      第57回日本栄養改善学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] Impact of smoking on the development of stroke and coronary heart disease in a general Japanese population : the Hisayama Study.2010

    • Author(s)
      Hata J, et al
    • Organizer
      Stroke society of Australasia 21st annual scientific meeting
    • Place of Presentation
      Melborne, Australia
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] NT-proBNPと心血管病の発症リスク2010

    • Author(s)
      土井康文, 他
    • Organizer
      第51回日本人間ドック学会学術大会
    • Place of Presentation
      旭川
    • Year and Date
      2010-08-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Impact of kidney disease and blood pressure on the development of cardiovascular disease : results from the Japan Arteriosclerosis Longitudinal Study.2010

    • Author(s)
      Ninomiya T, et al
    • Organizer
      International academy of cardiology 15th world congress on heart disease annual scientific sessions 2010
    • Place of Presentation
      Vancouver, B.C., Canada
    • Year and Date
      2010-07-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域住民における耐糖能レベルが認知症発症におよぼす影響:久山町研究2010

    • Author(s)
      小原知之, 他
    • Organizer
      第52回日本老年医学会学術集会・総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 認知症の疫学調査:久山町研究2010

    • Author(s)
      清原裕
    • Organizer
      第25回日本老年精神医学会
    • Place of Presentation
      熊本
    • Year and Date
      2010-06-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域高齢者における日常生活動作障害の現状と原因疾患:久山町研究2010

    • Author(s)
      吉田大悟, 他
    • Organizer
      第52回日本老年医学会学術集会・総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 久山町研究におけるCKDの最新知見2010

    • Author(s)
      清原裕
    • Organizer
      第53回日本腎臓病学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 腎機能低下および蛋白尿が心血管病死に及ぼす影響:EPOCH-JAPAN研究2010

    • Author(s)
      永田雅治, 他
    • Organizer
      第53回日本腎臓病学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肝機能障害が糖尿病および心血管病の発症に及ぼす影響2010

    • Author(s)
      土井康文, 他
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 一般住民におけるメタボリックシンドロームの診断基準と慢性腎臓病発症の関係:久山町研究2010

    • Author(s)
      永田雅治, 他
    • Organizer
      第46回日本循環器病予防学会・日本循環器管理研究協議会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域一般住民における糖尿病発症に対する空腹時および糖負荷後2時間血糖値のカットオフ値の検討:久山町研究2010

    • Author(s)
      向井直子, 他
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域一般住民における血中レジスチンと慢性腎臓病(CKD)の関係:久山町研究2010

    • Author(s)
      川村良一, 他
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域住民におけるHbA1cレベルが悪性腫瘍死におよぼす影響:久山町研究2010

    • Author(s)
      平川洋一郎, 他
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肝機能障害が糖尿病および心血管病の発症に及ぼす影響2010

    • Author(s)
      土井康文, 他
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形市
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地域住民における糖尿病・耐糖能異常が認知症発症におよぼす影響:久山町研究2010

    • Author(s)
      小原知之, 他
    • Organizer
      第106回日本精神神経学会
    • Place of Presentation
      広島市
    • Year and Date
      2010-05-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 久山町研究を基盤とした脳梗塞のゲノムワイド関連研究2010

    • Author(s)
      秦淳, 他
    • Organizer
      第80回日本衛生学会学術総会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-05-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 急増する代謝性疾患が脳梗塞発症に及ぼす影響:久山町研究2010

    • Author(s)
      土井康文, 他
    • Organizer
      第35回日本脳卒中学会総会
    • Place of Presentation
      盛岡市
    • Year and Date
      2010-04-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 慢性疼痛と失感情症は一般住民の生活満足度を低下させる:久山町疫学研究2010

    • Author(s)
      柴田舞欧, 他
    • Organizer
      第40回日本慢性疼痛学会
    • Place of Presentation
      東京
    • Year and Date
      2010-02-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 糖尿病と癌-久山町研究から.糖尿病学会と癌学会の合同シンポジウム(シンポジウム)

    • Author(s)
      清原 裕
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 日本人の生活習慣病の時代的変遷~半世紀に及ぶ久山町からのメッセージ~(特別講演)

    • Author(s)
      清原 裕
    • Organizer
      第9回日本食品免疫学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 循環器疾患発症リスクと検査値の未病域:久山町研究.未病ガイドライン(シンポジウム)

    • Author(s)
      清原 裕
    • Organizer
      第20回日本未病システム学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 我が国の循環器疾患とリスク因子の時代変遷.(モーニングレクチャー)

    • Author(s)
      清原 裕
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] アクチュアル脳・神経疾患の臨床 脳血管障害の治療最前線(分担執筆)2014

    • Author(s)
      清原 裕
    • Total Pages
      7
    • Publisher
      中山書店
    • Related Report
      2014 Annual Research Report
  • [Book] 臨床研究のススメ.5.コホート研究─久山町スタディの最近の成果─2014

    • Author(s)
      清原 裕
    • Total Pages
      6
    • Publisher
      最新医学社
    • Related Report
      2013 Annual Research Report
  • [Book] 脳神経外科診療プラクティス 1 脳血管障害の急性期マネジメント.II 臨床医に必要な脳血管障害の基礎知識.5.脳血管障害の疫学と高齢化社会における課題2014

    • Author(s)
      清原 裕
    • Total Pages
      5
    • Publisher
      光文堂
    • Related Report
      2013 Annual Research Report
  • [Book] 高血圧診療のすべて.I 疫学,遺伝.日本人の心血管リスク因子の変遷2013

    • Author(s)
      清原 裕
    • Total Pages
      4
    • Publisher
      診断と治療社
    • Related Report
      2013 Annual Research Report
  • [Book] "脳とこころのプライマリケア.第2巻 知能の衰え.II章 総論.認知症の疫学2013

    • Author(s)
      清原 裕
    • Total Pages
      13
    • Publisher
      シナジー
    • Related Report
      2013 Annual Research Report
  • [Book] 第Ⅱ章 循環器予防医学総論. 1.マクロからみた疫学的予防医学. エビデンスに基づく循環器病予防医学-慢性心不全を防ぐ予防戦略とは?-2012

    • Author(s)
      清原 裕、他
    • Total Pages
      9
    • Publisher
      南山堂
    • Related Report
      2012 Annual Research Report
  • [Book] 脳血管障害の分類, 疫学. Question1.疫学データに基づく脳卒中の動向と危険因子の推移について教えてください. 脳卒中診療 こんなときどうするQA第2版2012

    • Author(s)
      清原 裕、他
    • Total Pages
      4
    • Publisher
      中外医学社
    • Related Report
      2012 Annual Research Report
  • [Book] 3章 疾患の疫学. 3.コホート研究:久山町研究. カラー版 内科学.2012

    • Author(s)
      清原 裕、他
    • Total Pages
      5
    • Publisher
      西村書店
    • Related Report
      2012 Annual Research Report
  • [Book] Visual糖尿病臨床のすべて2011

    • Author(s)
      平川洋一郎, 他
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report
  • [Book] 糖尿病学20112011

    • Author(s)
      向井直子, 他
    • Publisher
      診断と治療社
    • Related Report
      2011 Annual Research Report
  • [Book] 高血圧ナビゲーター2011

    • Author(s)
      清原裕, 他
    • Publisher
      メディカルレビュー社
    • Related Report
      2011 Annual Research Report
  • [Book] すべてがわかる最新糖尿病2011

    • Author(s)
      清原裕, 他
    • Publisher
      照林社
    • Related Report
      2011 Annual Research Report
  • [Book] 脳卒中の定義・分類・疫学脳卒中の最新疫学2010

    • Author(s)
      後藤誠司・清原裕
    • Total Pages
      300
    • Publisher
      最新医学社
    • Related Report
      2010 Annual Research Report
  • [Book] 糖尿病大血管障害2010

    • Author(s)
      向井直子, 清原裕
    • Publisher
      南江堂
    • Related Report
      2010 Annual Research Report
  • [Book] コメディカル・研修医・一般臨床医のための糖尿病治療ハンドブック2010

    • Author(s)
      清原裕
    • Publisher
      医学出版
    • Related Report
      2010 Annual Research Report
  • [Book] 心血管リスクとしてのCKD2010

    • Author(s)
      碓井知子、清原裕
    • Publisher
      中山書店
    • Related Report
      2010 Annual Research Report
  • [Book] 脳血管障害の臨床疫学2010

    • Author(s)
      清原裕
    • Publisher
      西村書店
    • Related Report
      2010 Annual Research Report
  • [Book] 脳卒中の最新疫学2010

    • Author(s)
      清原裕
    • Publisher
      最新医学社
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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